Alternaria-derived serine protease activity drives IL-33-mediated asthma exacerbations

Journal of Allergy and Clinical Immunology

Volumn 134, Issue 3, 2014, Pages

  Snelgrove, Robert J ^a   Gregory, Lisa G ^a   Peiró, Teresa ^a   Akthar, Samia ^a   Campbell, Gaynor A ^a   Walker, Simone A ^a   Lloyd, Clare M ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

allergic airway disease; Alternaria alternata; asthma exacerbation; IL 33; protease

Indexed keywords

ADENOSINE TRIPHOSPHATE; INTERLEUKIN 13; INTERLEUKIN 1BETA; INTERLEUKIN 33; INTERLEUKIN 5; LACTATE DEHYDROGENASE; PROTEINASE ACTIVATED RECEPTOR 2; SERINE PROTEINASE; FUNGAL PROTEIN; HOUSE DUST ALLERGEN; IL1RL1 PROTEIN, MOUSE; IL33 PROTEIN, MOUSE; INTERLEUKIN DERIVATIVE; INTERLEUKIN RECEPTOR;

ALTERNARIA ALTERNATA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTHMA; CELL DAMAGE; CELL INFILTRATION; CELL LOSS; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOKINE RESPONSE; DANDER; DERMATOPHAGOIDES; DISEASE EXACERBATION; ENZYME ACTIVITY; EOSINOPHIL; FEMALE; IN VITRO STUDY; INFLAMMATORY CELL; LUNG FUNCTION; MACROPHAGE; MOUSE; NEUTROPHIL; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ALTERNARIA; ALTERNARIOSIS; ANIMAL; BAGG ALBINO MOUSE; DISEASE COURSE; DISEASE MODEL; GENETICS; HUMAN; HYPERSENSITIVITY; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; MICROBIOLOGY; PYROGLYPHIDAE;

ADENOSINE TRIPHOSPHATE; ALTERNARIA; ALTERNARIOSIS; ANIMALS; ANTIGENS, DERMATOPHAGOIDES; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; FEMALE; FUNGAL PROTEINS; HUMANS; HYPERSENSITIVITY; INTERLEUKIN-33; INTERLEUKINS; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; PYROGLYPHIDAE; RECEPTOR, PAR-2; RECEPTORS, INTERLEUKIN; SERINE PROTEASES; SIGNAL TRANSDUCTION;

EID: 84905968184     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2014.02.002     Document Type: Article

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