-
1
-
-
0024408824
-
Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones
-
Fiorentino DF, Bond MW, Mosmann TR. Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J Exp Med. 1989;170:2081-95.
-
(1989)
J Exp Med
, vol.170
, pp. 2081-2095
-
-
Fiorentino, D.F.1
Bond, M.W.2
Mosmann, T.R.3
-
2
-
-
34249678457
-
T(H)1 cells control themselves by producing interleukin-10
-
O'Garra A, Vieira P. T(H)1 cells control themselves by producing interleukin-10. Nat Rev Immunol. 2007;7:425-8.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 425-428
-
-
O'Garra, A.1
Vieira, P.2
-
3
-
-
0027521572
-
Interleukin-10-deficient mice develop chronic enterocolitis
-
Kuhn R, Lohler J, Rennick D, Rajewsky K, Muller W. Interleukin-10-deficient mice develop chronic enterocolitis. Cell. 1993;75:263-74.
-
(1993)
Cell
, vol.75
, pp. 263-274
-
-
Kuhn, R.1
Lohler, J.2
Rennick, D.3
Rajewsky, K.4
Muller, W.5
-
4
-
-
84958539762
-
IL-10 in humans: lessons from the gut, IL-10/IL-10 receptor deficiencies, and IL-10 polymorphisms
-
Engelhardt KR, Grimbacher B. IL-10 in humans: lessons from the gut, IL-10/IL-10 receptor deficiencies, and IL-10 polymorphisms. Curr Top Microbiol Immunol. 2014;380:1-18.
-
(2014)
Curr Top Microbiol Immunol
, vol.380
, pp. 1-18
-
-
Engelhardt, K.R.1
Grimbacher, B.2
-
6
-
-
77649184739
-
The regulation of IL-10 production by immune cells
-
Saraiva M, O'Garra A. The regulation of IL-10 production by immune cells. Nat Rev Immunol. 2010;10:170-81.
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 170-181
-
-
Saraiva, M.1
O'Garra, A.2
-
7
-
-
84930927235
-
The therapeutic potential of interleukin-10 in neuroimmune diseases
-
Kwilasz AJ, Grace PM, Serbedzija P, Maier SF, Watkins LR. The therapeutic potential of interleukin-10 in neuroimmune diseases. Neuropharmacology. 2015;96:55-69.
-
(2015)
Neuropharmacology
, vol.96
, pp. 55-69
-
-
Kwilasz, A.J.1
Grace, P.M.2
Serbedzija, P.3
Maier, S.F.4
Watkins, L.R.5
-
8
-
-
40549113336
-
Mucosal IL-10 and TGF-beta play crucial roles in preventing LPS-driven, IFN-gamma-mediated epithelial damage in human colon explants
-
Jarry A, Bossard C, Bou-Hanna C, Masson D, Espaze E, Denis MG, Laboisse CL. Mucosal IL-10 and TGF-beta play crucial roles in preventing LPS-driven, IFN-gamma-mediated epithelial damage in human colon explants. J Clin Invest. 2008;118:1132-42.
-
(2008)
J Clin Invest
, vol.118
, pp. 1132-1142
-
-
Jarry, A.1
Bossard, C.2
Bou-Hanna, C.3
Masson, D.4
Espaze, E.5
Denis, M.G.6
Laboisse, C.L.7
-
10
-
-
66449130960
-
Regulation of innate immune responses in the brain
-
Rivest S. Regulation of innate immune responses in the brain. Nat Rev Immunol. 2009;9:429-39.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 429-439
-
-
Rivest, S.1
-
11
-
-
84876784407
-
Innate immunity in the CNS: redefining the relationship between the CNS and Its environment
-
Lampron A, Elali A, Rivest S. Innate immunity in the CNS: redefining the relationship between the CNS and Its environment. Neuron. 2013;78:214-32.
-
(2013)
Neuron
, vol.78
, pp. 214-232
-
-
Lampron, A.1
Elali, A.2
Rivest, S.3
-
12
-
-
84936871460
-
Structural and functional features of central nervous system lymphatic vessels
-
Louveau A, Smirnov I, Keyes TJ, Eccles JD, Rouhani SJ, Peske JD, Derecki NC, Castle D, Mandell JW, Lee KS, et al. Structural and functional features of central nervous system lymphatic vessels. Nature. 2015;523:337-41.
-
(2015)
Nature
, vol.523
, pp. 337-341
-
-
Louveau, A.1
Smirnov, I.2
Keyes, T.J.3
Eccles, J.D.4
Rouhani, S.J.5
Peske, J.D.6
Derecki, N.C.7
Castle, D.8
Mandell, J.W.9
Lee, K.S.10
-
13
-
-
84942469639
-
A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules
-
Aspelund A, Antila S, Proulx ST, Karlsen TV, Karaman S, Detmar M, Wiig H, Alitalo K. A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules. J Exp Med. 2015;212:991-9.
-
(2015)
J Exp Med
, vol.212
, pp. 991-999
-
-
Aspelund, A.1
Antila, S.2
Proulx, S.T.3
Karlsen, T.V.4
Karaman, S.5
Detmar, M.6
Wiig, H.7
Alitalo, K.8
-
14
-
-
70449529633
-
The blood-brain barrier and immune function and dysfunction
-
Banks WA, Erickson MA. The blood-brain barrier and immune function and dysfunction. Neurobiol Dis. 2010;37:26-32.
-
(2010)
Neurobiol Dis
, vol.37
, pp. 26-32
-
-
Banks, W.A.1
Erickson, M.A.2
-
15
-
-
84925441813
-
Control of adaptive immunity by the innate immune system
-
Iwasaki A, Medzhitov R. Control of adaptive immunity by the innate immune system. Nat Immunol. 2015;16:343-53.
-
(2015)
Nat Immunol
, vol.16
, pp. 343-353
-
-
Iwasaki, A.1
Medzhitov, R.2
-
16
-
-
77950343791
-
Pattern recognition receptors and inflammation
-
Takeuchi O, Akira S. Pattern recognition receptors and inflammation. Cell. 2010;140:805-20.
-
(2010)
Cell
, vol.140
, pp. 805-820
-
-
Takeuchi, O.1
Akira, S.2
-
17
-
-
34548358816
-
Toll-like receptors modulate adult hippocampal neurogenesis
-
Rolls A, Shechter R, London A, Ziv Y, Ronen A, Levy R, Schwartz M. Toll-like receptors modulate adult hippocampal neurogenesis. Nat Cell Biol. 2007;9:1081-8.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 1081-1088
-
-
Rolls, A.1
Shechter, R.2
London, A.3
Ziv, Y.4
Ronen, A.5
Levy, R.6
Schwartz, M.7
-
18
-
-
77953831096
-
TLR2 activation inhibits embryonic neural progenitor cell proliferation
-
Okun E, Griffioen KJ, Son TG, Lee JH, Roberts NJ, Mughal MR, Hutchison E, Cheng A, Arumugam TV, Lathia JD, et al. TLR2 activation inhibits embryonic neural progenitor cell proliferation. J Neurochem. 2010;114:462-74.
-
(2010)
J Neurochem
, vol.114
, pp. 462-474
-
-
Okun, E.1
Griffioen, K.J.2
Son, T.G.3
Lee, J.H.4
Roberts, N.J.5
Mughal, M.R.6
Hutchison, E.7
Cheng, A.8
Arumugam, T.V.9
Lathia, J.D.10
-
19
-
-
77957255968
-
Toll-like receptor 3 inhibits memory retention and constrains adult hippocampal neurogenesis
-
Okun E, Griffioen K, Barak B, Roberts NJ, Castro K, Pita MA, Cheng A, Mughal MR, Wan R, Ashery U, Mattson MP. Toll-like receptor 3 inhibits memory retention and constrains adult hippocampal neurogenesis. Proc Natl Acad Sci U S A. 2010;107:15625-30.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 15625-15630
-
-
Okun, E.1
Griffioen, K.2
Barak, B.3
Roberts, N.J.4
Castro, K.5
Pita, M.A.6
Cheng, A.7
Mughal, M.R.8
Wan, R.9
Ashery, U.10
Mattson, M.P.11
-
20
-
-
84862649049
-
Toll-like receptor (TLR) and inflammasome actions in the central nervous system
-
Hanamsagar R, Hanke ML, Kielian T. Toll-like receptor (TLR) and inflammasome actions in the central nervous system. Trends Immunol. 2012;33:333-42.
-
(2012)
Trends Immunol
, vol.33
, pp. 333-342
-
-
Hanamsagar, R.1
Hanke, M.L.2
Kielian, T.3
-
21
-
-
84960388165
-
Microglial physiology and pathophysiology: insights from genome-wide transcriptional profiling
-
Crotti A, Ransohoff RM. Microglial physiology and pathophysiology: insights from genome-wide transcriptional profiling. Immunity. 2016;44:505-15.
-
(2016)
Immunity
, vol.44
, pp. 505-515
-
-
Crotti, A.1
Ransohoff, R.M.2
-
22
-
-
78149360132
-
Fate mapping analysis reveals that adult microglia derive from primitive macrophages
-
Ginhoux F, Greter M, Leboeuf M, Nandi S, See P, Gokhan S, Mehler MF, Conway SJ, Ng LG, Stanley ER, et al. Fate mapping analysis reveals that adult microglia derive from primitive macrophages. Science. 2010;330:841-5.
-
(2010)
Science
, vol.330
, pp. 841-845
-
-
Ginhoux, F.1
Greter, M.2
Leboeuf, M.3
Nandi, S.4
See, P.5
Gokhan, S.6
Mehler, M.F.7
Conway, S.J.8
Ng, L.G.9
Stanley, E.R.10
-
23
-
-
84875892857
-
Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways
-
Kierdorf K, Erny D, Goldmann T, Sander V, Schulz C, Perdiguero EG, Wieghofer P, Heinrich A, Riemke P, Holscher C, et al. Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways. Nat Neurosci. 2013;16:273-80.
-
(2013)
Nat Neurosci
, vol.16
, pp. 273-280
-
-
Kierdorf, K.1
Erny, D.2
Goldmann, T.3
Sander, V.4
Schulz, C.5
Perdiguero, E.G.6
Wieghofer, P.7
Heinrich, A.8
Riemke, P.9
Holscher, C.10
-
24
-
-
84892493826
-
Cell fate control in the developing central nervous system
-
Guerout N, Li X, Barnabe-Heider F. Cell fate control in the developing central nervous system. Exp Cell Res. 2014;321:77-83.
-
(2014)
Exp Cell Res
, vol.321
, pp. 77-83
-
-
Guerout, N.1
Li, X.2
Barnabe-Heider, F.3
-
25
-
-
36448994709
-
Local self-renewal can sustain CNS microglia maintenance and function throughout adult life
-
Ajami B, Bennett JL, Krieger C, Tetzlaff W, Rossi FM. Local self-renewal can sustain CNS microglia maintenance and function throughout adult life. Nat Neurosci. 2007;10:1538-43.
-
(2007)
Nat Neurosci
, vol.10
, pp. 1538-1543
-
-
Ajami, B.1
Bennett, J.L.2
Krieger, C.3
Tetzlaff, W.4
Rossi, F.M.5
-
26
-
-
84905116959
-
Differential roles of microglia and monocytes in the inflamed central nervous system
-
Yamasaki R, Lu H, Butovsky O, Ohno N, Rietsch AM, Cialic R, Wu PM, Doykan CE, Lin J, Cotleur AC, et al. Differential roles of microglia and monocytes in the inflamed central nervous system. J Exp Med. 2014;211:1533-49.
-
(2014)
J Exp Med
, vol.211
, pp. 1533-1549
-
-
Yamasaki, R.1
Lu, H.2
Butovsky, O.3
Ohno, N.4
Rietsch, A.M.5
Cialic, R.6
Wu, P.M.7
Doykan, C.E.8
Lin, J.9
Cotleur, A.C.10
-
27
-
-
84893579839
-
Innate and adaptive immune responses in neurodegeneration and repair
-
Amor S, Woodroofe MN. Innate and adaptive immune responses in neurodegeneration and repair. Immunology. 2014;141:287-91.
-
(2014)
Immunology
, vol.141
, pp. 287-291
-
-
Amor, S.1
Woodroofe, M.N.2
-
28
-
-
80355143546
-
Microglial cell origin and phenotypes in health and disease
-
Saijo K, Glass CK. Microglial cell origin and phenotypes in health and disease. Nat Rev Immunol. 2011;11:775-87.
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 775-787
-
-
Saijo, K.1
Glass, C.K.2
-
29
-
-
84953353921
-
Microglial toll-like receptors and Alzheimer's disease
-
Su F, Bai F, Zhou H, Zhang Z. Microglial toll-like receptors and Alzheimer's disease. Brain Behav Immun. 2016;52:187-98.
-
(2016)
Brain Behav Immun
, vol.52
, pp. 187-198
-
-
Su, F.1
Bai, F.2
Zhou, H.3
Zhang, Z.4
-
30
-
-
84899062441
-
Inflammation in neurodegenerative diseases-an update
-
Amor S, Peferoen LA, Vogel DY, Breur M, van der Valk P, Baker D, van Noort JM. Inflammation in neurodegenerative diseases-an update. Immunology. 2014;142:151-66.
-
(2014)
Immunology
, vol.142
, pp. 151-166
-
-
Amor, S.1
Peferoen, L.A.2
Vogel, D.Y.3
Breur, M.4
Valk, P.5
Baker, D.6
Noort, J.M.7
-
31
-
-
84983032256
-
The relation between alpha-synuclein and microglia in Parkinson's disease: recent developments
-
Sanchez-Guajardo V, Tentillier N, Romero-Ramos M. The relation between alpha-synuclein and microglia in Parkinson's disease: recent developments. Neuroscience. 2015;302:47-58.
-
(2015)
Neuroscience
, vol.302
, pp. 47-58
-
-
Sanchez-Guajardo, V.1
Tentillier, N.2
Romero-Ramos, M.3
-
32
-
-
78650518775
-
Cognitive deficits in experimental autoimmune encephalomyelitis: neuroinflammation and synaptic degeneration
-
Mandolesi G, Grasselli G, Musumeci G, Centonze D. Cognitive deficits in experimental autoimmune encephalomyelitis: neuroinflammation and synaptic degeneration. Neurol Sci. 2010;31:S255-9.
-
(2010)
Neurol Sci
, vol.31
, pp. S255-S259
-
-
Mandolesi, G.1
Grasselli, G.2
Musumeci, G.3
Centonze, D.4
-
33
-
-
33847099936
-
Astrocytes are active players in cerebral innate immunity
-
Farina C, Aloisi F, Meinl E. Astrocytes are active players in cerebral innate immunity. Trends Immunol. 2007;28:138-45.
-
(2007)
Trends Immunol
, vol.28
, pp. 138-145
-
-
Farina, C.1
Aloisi, F.2
Meinl, E.3
-
34
-
-
25444498280
-
TLR signaling tailors innate immune responses in human microglia and astrocytes
-
Jack CS, Arbour N, Manusow J, Montgrain V, Blain M, McCrea E, Shapiro A, Antel JP. TLR signaling tailors innate immune responses in human microglia and astrocytes. J Immunol. 2005;175:4320-30.
-
(2005)
J Immunol
, vol.175
, pp. 4320-4330
-
-
Jack, C.S.1
Arbour, N.2
Manusow, J.3
Montgrain, V.4
Blain, M.5
McCrea, E.6
Shapiro, A.7
Antel, J.P.8
-
35
-
-
0036841178
-
Broad expression of Toll-like receptors in the human central nervous system
-
Bsibsi M, Ravid R, Gveric D, van Noort JM. Broad expression of Toll-like receptors in the human central nervous system. J Neuropathol Exp Neurol. 2002;61:1013-21.
-
(2002)
J Neuropathol Exp Neurol
, vol.61
, pp. 1013-1021
-
-
Bsibsi, M.1
Ravid, R.2
Gveric, D.3
Noort, J.M.4
-
36
-
-
35348860696
-
Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits
-
Tang SC, Arumugam TV, Xu X, Cheng A, Mughal MR, Jo DG, Lathia JD, Siler DA, Chigurupati S, Ouyang X, et al. Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits. Proc Natl Acad Sci U S A. 2007;104:13798-803.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 13798-13803
-
-
Tang, S.C.1
Arumugam, T.V.2
Xu, X.3
Cheng, A.4
Mughal, M.R.5
Jo, D.G.6
Lathia, J.D.7
Siler, D.A.8
Chigurupati, S.9
Ouyang, X.10
-
37
-
-
33750601026
-
The innate immune facet of brain: human neurons express TLR-3 and sense viral dsRNA
-
Lafon M, Megret F, Lafage M, Prehaud C. The innate immune facet of brain: human neurons express TLR-3 and sense viral dsRNA. J Mol Neurosci. 2006;29:185-94.
-
(2006)
J Mol Neurosci
, vol.29
, pp. 185-194
-
-
Lafon, M.1
Megret, F.2
Lafage, M.3
Prehaud, C.4
-
38
-
-
84882329201
-
An evolving new paradigm: endothelial cells-conditional innate immune cells
-
Mai J, Virtue A, Shen J, Wang H, Yang XF. An evolving new paradigm: endothelial cells-conditional innate immune cells. J Hematol Oncol. 2013;6:61.
-
(2013)
J Hematol Oncol
, vol.6
, pp. 61
-
-
Mai, J.1
Virtue, A.2
Shen, J.3
Wang, H.4
Yang, X.F.5
-
39
-
-
33745700364
-
Understanding and exploiting the endogenous interleukin-10/STAT3-mediated anti-inflammatory response
-
Murray PJ. Understanding and exploiting the endogenous interleukin-10/STAT3-mediated anti-inflammatory response. Curr Opin Pharmacol. 2006;6:379-86.
-
(2006)
Curr Opin Pharmacol
, vol.6
, pp. 379-386
-
-
Murray, P.J.1
-
41
-
-
0036430203
-
Expression and regulation of interleukin-10 and interleukin-10 receptor in rat astroglial and microglial cells
-
Ledeboer A, Breve JJ, Wierinckx A, van der Jagt S, Bristow AF, Leysen JE, Tilders FJ, Van Dam AM. Expression and regulation of interleukin-10 and interleukin-10 receptor in rat astroglial and microglial cells. Eur J Neurosci. 2002;16:1175-85.
-
(2002)
Eur J Neurosci
, vol.16
, pp. 1175-1185
-
-
Ledeboer, A.1
Breve, J.J.2
Wierinckx, A.3
Jagt, S.4
Bristow, A.F.5
Leysen, J.E.6
Tilders, F.J.7
Dam, A.M.8
-
42
-
-
9244260503
-
Attenuation of astroglial reactivity by interleukin-10
-
Balasingam V, Yong VW. Attenuation of astroglial reactivity by interleukin-10. J Neurosci. 1996;16:2945-55.
-
(1996)
J Neurosci
, vol.16
, pp. 2945-2955
-
-
Balasingam, V.1
Yong, V.W.2
-
43
-
-
84898027883
-
TGFbeta produced by IL-10 redirected astrocytes attenuates microglial activation
-
Norden DM, Fenn AM, Dugan A, Godbout JP. TGFbeta produced by IL-10 redirected astrocytes attenuates microglial activation. Glia. 2014;62:881-95.
-
(2014)
Glia
, vol.62
, pp. 881-895
-
-
Norden, D.M.1
Fenn, A.M.2
Dugan, A.3
Godbout, J.P.4
-
44
-
-
68949212050
-
Interleukin-10 provides direct trophic support to neurons
-
Zhou Z, Peng X, Insolera R, Fink DJ, Mata M. Interleukin-10 provides direct trophic support to neurons. J Neurochem. 2009;110:1617-27.
-
(2009)
J Neurochem
, vol.110
, pp. 1617-1627
-
-
Zhou, Z.1
Peng, X.2
Insolera, R.3
Fink, D.J.4
Mata, M.5
-
45
-
-
70349730234
-
IL-10 promotes neuronal survival following spinal cord injury
-
Zhou Z, Peng X, Insolera R, Fink DJ, Mata M. IL-10 promotes neuronal survival following spinal cord injury. Exp Neurol. 2009;220:183-90.
-
(2009)
Exp Neurol
, vol.220
, pp. 183-190
-
-
Zhou, Z.1
Peng, X.2
Insolera, R.3
Fink, D.J.4
Mata, M.5
-
46
-
-
84925114381
-
IL-10 regulates adult neurogenesis by modulating ERK and STAT3 activity
-
Pereira L, Font-Nieves M, Van den Haute C, Baekelandt V, Planas AM, Pozas E. IL-10 regulates adult neurogenesis by modulating ERK and STAT3 activity. Front Cell Neurosci. 2015;9:57.
-
(2015)
Front Cell Neurosci
, vol.9
, pp. 57
-
-
Pereira, L.1
Font-Nieves, M.2
Haute, C.3
Baekelandt, V.4
Planas, A.M.5
Pozas, E.6
-
47
-
-
84885460123
-
Interleukin-10 regulates progenitor differentiation and modulates neurogenesis in adult brain
-
Perez-Asensio FJ, Perpina U, Planas AM, Pozas E. Interleukin-10 regulates progenitor differentiation and modulates neurogenesis in adult brain. J Cell Sci. 2013;126:4208-19.
-
(2013)
J Cell Sci
, vol.126
, pp. 4208-4219
-
-
Perez-Asensio, F.J.1
Perpina, U.2
Planas, A.M.3
Pozas, E.4
-
48
-
-
2942612995
-
Wallerian degeneration after crush or chronic constriction injury of rodent sciatic nerve is associated with a depletion of endoneurial interleukin-10 protein
-
George A, Kleinschnitz C, Zelenka M, Brinkhoff J, Stoll G, Sommer C. Wallerian degeneration after crush or chronic constriction injury of rodent sciatic nerve is associated with a depletion of endoneurial interleukin-10 protein. Exp Neurol. 2004;188:187-91.
-
(2004)
Exp Neurol
, vol.188
, pp. 187-191
-
-
George, A.1
Kleinschnitz, C.2
Zelenka, M.3
Brinkhoff, J.4
Stoll, G.5
Sommer, C.6
-
49
-
-
78751522947
-
Disease protection and interleukin-10 induction by endogenous interferon-beta in multiple sclerosis?
-
Hesse D, Krakauer M, Lund H, Sondergaard HB, Limborg SJ, Sorensen PS, Sellebjerg F. Disease protection and interleukin-10 induction by endogenous interferon-beta in multiple sclerosis? Eur J Neurol. 2011;18:266-72.
-
(2011)
Eur J Neurol
, vol.18
, pp. 266-272
-
-
Hesse, D.1
Krakauer, M.2
Lund, H.3
Sondergaard, H.B.4
Limborg, S.J.5
Sorensen, P.S.6
Sellebjerg, F.7
-
50
-
-
0032975730
-
Decreased interleukin-10 and increased interleukin-12p40 mRNA are associated with disease activity and characterize different disease stages in multiple sclerosis
-
van Boxel-Dezaire AH, Hoff SC, van Oosten BW, Verweij CL, Drager AM, Ader HJ, van Houwelingen JC, Barkhof F, Polman CH, Nagelkerken L. Decreased interleukin-10 and increased interleukin-12p40 mRNA are associated with disease activity and characterize different disease stages in multiple sclerosis. Ann Neurol. 1999;45:695-703.
-
(1999)
Ann Neurol
, vol.45
, pp. 695-703
-
-
Boxel-Dezaire, A.H.1
Hoff, S.C.2
Oosten, B.W.3
Verweij, C.L.4
Drager, A.M.5
Ader, H.J.6
Houwelingen, J.C.7
Barkhof, F.8
Polman, C.H.9
Nagelkerken, L.10
-
51
-
-
84863717973
-
AAV serotype 2/1-mediated gene delivery of anti-inflammatory interleukin-10 enhances neurogenesis and cognitive function in APP+PS1 mice
-
Kiyota T, Ingraham KL, Swan RJ, Jacobsen MT, Andrews SJ, Ikezu T. AAV serotype 2/1-mediated gene delivery of anti-inflammatory interleukin-10 enhances neurogenesis and cognitive function in APP+PS1 mice. Gene Ther. 2012;19:724-33.
-
(2012)
Gene Ther
, vol.19
, pp. 724-733
-
-
Kiyota, T.1
Ingraham, K.L.2
Swan, R.J.3
Jacobsen, M.T.4
Andrews, S.J.5
Ikezu, T.6
-
52
-
-
34247157292
-
Interleukin-10 protects against inflammation-mediated degeneration of dopaminergic neurons in substantia nigra
-
Arimoto T, Choi DY, Lu X, Liu M, Nguyen XV, Zheng N, Stewart CA, Kim HC, Bing G. Interleukin-10 protects against inflammation-mediated degeneration of dopaminergic neurons in substantia nigra. Neurobiol Aging. 2007;28:894-906.
-
(2007)
Neurobiol Aging
, vol.28
, pp. 894-906
-
-
Arimoto, T.1
Choi, D.Y.2
Lu, X.3
Liu, M.4
Nguyen, X.V.5
Zheng, N.6
Stewart, C.A.7
Kim, H.C.8
Bing, G.9
-
54
-
-
84960448094
-
Microglial P2Y12 is necessary for synaptic plasticity in mouse visual cortex
-
Sipe GO, Lowery RL, Tremblay ME, Kelly EA, Lamantia CE, Majewska AK. Microglial P2Y12 is necessary for synaptic plasticity in mouse visual cortex. Nat Commun. 2016;7:10905.
-
(2016)
Nat Commun
, vol.7
, pp. 10905
-
-
Sipe, G.O.1
Lowery, R.L.2
Tremblay, M.E.3
Kelly, E.A.4
Lamantia, C.E.5
Majewska, A.K.6
-
55
-
-
80052633284
-
Synaptic pruning by microglia is necessary for normal brain development
-
Paolicelli RC, Bolasco G, Pagani F, Maggi L, Scianni M, Panzanelli P, Giustetto M, Ferreira TA, Guiducci E, Dumas L, et al. Synaptic pruning by microglia is necessary for normal brain development. Science. 2011;333:1456-8.
-
(2011)
Science
, vol.333
, pp. 1456-1458
-
-
Paolicelli, R.C.1
Bolasco, G.2
Pagani, F.3
Maggi, L.4
Scianni, M.5
Panzanelli, P.6
Giustetto, M.7
Ferreira, T.A.8
Guiducci, E.9
Dumas, L.10
-
56
-
-
67650485985
-
Alternative activation of macrophages: an immunologic functional perspective
-
Martinez FO, Helming L, Gordon S. Alternative activation of macrophages: an immunologic functional perspective. Annu Rev Immunol. 2009;27:451-83.
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 451-483
-
-
Martinez, F.O.1
Helming, L.2
Gordon, S.3
-
57
-
-
84909987977
-
Microglia and inflammation: conspiracy, controversy or control?
-
Fernandes A, Miller-Fleming L, Pais TF. Microglia and inflammation: conspiracy, controversy or control? Cell Mol Life Sci. 2014;71:3969-85.
-
(2014)
Cell Mol Life Sci
, vol.71
, pp. 3969-3985
-
-
Fernandes, A.1
Miller-Fleming, L.2
Pais, T.F.3
-
58
-
-
84941421076
-
Diversity and plasticity of microglial cells in psychiatric and neurological disorders
-
Nakagawa Y, Chiba K. Diversity and plasticity of microglial cells in psychiatric and neurological disorders. Pharmacol Ther. 2015;154:21-35.
-
(2015)
Pharmacol Ther
, vol.154
, pp. 21-35
-
-
Nakagawa, Y.1
Chiba, K.2
-
59
-
-
84958106930
-
Differential roles of M1 and M2 microglia in neurodegenerative diseases
-
Tang Y, Le W. Differential roles of M1 and M2 microglia in neurodegenerative diseases. Mol Neurobiol. 2016;53:1181-94.
-
(2016)
Mol Neurobiol
, vol.53
, pp. 1181-1194
-
-
Tang, Y.1
Le, W.2
-
60
-
-
84931272233
-
Microglial activation as a compelling target for treating acute traumatic brain injury
-
Chio CC, Lin MT, Chang CP. Microglial activation as a compelling target for treating acute traumatic brain injury. Curr Med Chem. 2015;22:759-70.
-
(2015)
Curr Med Chem
, vol.22
, pp. 759-770
-
-
Chio, C.C.1
Lin, M.T.2
Chang, C.P.3
-
61
-
-
84928675725
-
Rational modulation of the innate immune system for neuroprotection in ischemic stroke
-
Amantea D, Micieli G, Tassorelli C, Cuartero MI, Ballesteros I, Certo M, Moro MA, Lizasoain I, Bagetta G. Rational modulation of the innate immune system for neuroprotection in ischemic stroke. Front Neurosci. 2015;9:147.
-
(2015)
Front Neurosci
, vol.9
, pp. 147
-
-
Amantea, D.1
Micieli, G.2
Tassorelli, C.3
Cuartero, M.I.4
Ballesteros, I.5
Certo, M.6
Moro, M.A.7
Lizasoain, I.8
Bagetta, G.9
-
62
-
-
84883454794
-
M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination
-
Miron VE, Boyd A, Zhao JW, Yuen TJ, Ruckh JM, Shadrach JL, van Wijngaarden P, Wagers AJ, Williams A, Franklin RJ, ffrench-Constant C. M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination. Nat Neurosci. 2013;16:1211-8.
-
(2013)
Nat Neurosci
, vol.16
, pp. 1211-1218
-
-
Miron, V.E.1
Boyd, A.2
Zhao, J.W.3
Yuen, T.J.4
Ruckh, J.M.5
Shadrach, J.L.6
Wijngaarden, P.7
Wagers, A.J.8
Williams, A.9
Franklin, R.J.10
ffrench-Constant, C.11
-
63
-
-
84974540858
-
Regulatory T cells ameliorate intracerebral hemorrhage-induced inflammatory injury by modulating microglia/macrophage polarization through the IL-10/GSK3beta/PTEN axis
-
Zhou K, Zhong Q, Wang YC, Xiong XY, Meng ZY, Zhao T, Zhu WY, Liao MF, Wu LR, Yang YR, et al. Regulatory T cells ameliorate intracerebral hemorrhage-induced inflammatory injury by modulating microglia/macrophage polarization through the IL-10/GSK3beta/PTEN axis. J Cereb Blood Flow Metab. 2016.
-
(2016)
J Cereb Blood Flow Metab
-
-
Zhou, K.1
Zhong, Q.2
Wang, Y.C.3
Xiong, X.Y.4
Meng, Z.Y.5
Zhao, T.6
Zhu, W.Y.7
Liao, M.F.8
Wu, L.R.9
Yang, Y.R.10
-
64
-
-
84938286568
-
Alternatively activated microglia and macrophages in the central nervous system
-
Franco R, Fernandez-Suarez D. Alternatively activated microglia and macrophages in the central nervous system. Prog Neurobiol. 2015;131:65-86.
-
(2015)
Prog Neurobiol
, vol.131
, pp. 65-86
-
-
Franco, R.1
Fernandez-Suarez, D.2
-
65
-
-
84977514700
-
IL-10-dependent Tr1 cells attenuate astrocyte activation and ameliorate chronic central nervous system inflammation
-
Mayo L, Cunha AP, Madi A, Beynon V, Yang Z, Alvarez JI, Prat A, Sobel RA, Kobzik L, Lassmann H, et al. IL-10-dependent Tr1 cells attenuate astrocyte activation and ameliorate chronic central nervous system inflammation. Brain. 2016;139:1939-57.
-
(2016)
Brain
, vol.139
, pp. 1939-1957
-
-
Mayo, L.1
Cunha, A.P.2
Madi, A.3
Beynon, V.4
Yang, Z.5
Alvarez, J.I.6
Prat, A.7
Sobel, R.A.8
Kobzik, L.9
Lassmann, H.10
-
66
-
-
84975057131
-
Role of regulatory b cells in neuroimmunologic disorders
-
Han J, Sun L, Fan X, Wang Z, Cheng Y, Zhu J, Jin T. Role of regulatory b cells in neuroimmunologic disorders. J Neurosci Res. 2016;94:693-701.
-
(2016)
J Neurosci Res
, vol.94
, pp. 693-701
-
-
Han, J.1
Sun, L.2
Fan, X.3
Wang, Z.4
Cheng, Y.5
Zhu, J.6
Jin, T.7
-
67
-
-
84930177232
-
Interleukin-10 paradox: a potent immunoregulatory cytokine that has been difficult to harness for immunotherapy
-
Saxena A, Khosraviani S, Noel S, Mohan D, Donner T, Hamad AR. Interleukin-10 paradox: a potent immunoregulatory cytokine that has been difficult to harness for immunotherapy. Cytokine. 2015;74:27-34.
-
(2015)
Cytokine
, vol.74
, pp. 27-34
-
-
Saxena, A.1
Khosraviani, S.2
Noel, S.3
Mohan, D.4
Donner, T.5
Hamad, A.R.6
-
68
-
-
0035159581
-
Central nervous system expression of IL-10 inhibits autoimmune encephalomyelitis
-
Cua DJ, Hutchins B, LaFace DM, Stohlman SA, Coffman RL. Central nervous system expression of IL-10 inhibits autoimmune encephalomyelitis. J Immunol. 2001;166:602-8.
-
(2001)
J Immunol
, vol.166
, pp. 602-608
-
-
Cua, D.J.1
Hutchins, B.2
LaFace, D.M.3
Stohlman, S.A.4
Coffman, R.L.5
-
69
-
-
0035869309
-
Different therapeutic outcomes in experimental allergic encephalomyelitis dependent upon the mode of delivery of IL-10: a comparison of the effects of protein, adenoviral or retroviral IL-10 delivery into the central nervous system
-
Croxford JL, Feldmann M, Chernajovsky Y, Baker D. Different therapeutic outcomes in experimental allergic encephalomyelitis dependent upon the mode of delivery of IL-10: a comparison of the effects of protein, adenoviral or retroviral IL-10 delivery into the central nervous system. J Immunol. 2001;166:4124-30.
-
(2001)
J Immunol
, vol.166
, pp. 4124-4130
-
-
Croxford, J.L.1
Feldmann, M.2
Chernajovsky, Y.3
Baker, D.4
-
70
-
-
84889095882
-
IL-10 deficiency exacerbates the brain inflammatory response to permanent ischemia without preventing resolution of the lesion
-
Perez-de Puig I, Miro F, Salas-Perdomo A, Bonfill-Teixidor E, Ferrer-Ferrer M, Marquez-Kisinousky L, Planas AM. IL-10 deficiency exacerbates the brain inflammatory response to permanent ischemia without preventing resolution of the lesion. J Cereb Blood Flow Metab. 2013;33:1955-66.
-
(2013)
J Cereb Blood Flow Metab
, vol.33
, pp. 1955-1966
-
-
Perez-de Puig, I.1
Miro, F.2
Salas-Perdomo, A.3
Bonfill-Teixidor, E.4
Ferrer-Ferrer, M.5
Marquez-Kisinousky, L.6
Planas, A.M.7
-
71
-
-
84902476451
-
The influence of AAV2-mediated gene transfer of human IL-10 on neurodegeneration and immune response in a murine model of Parkinson's disease
-
Joniec-Maciejak I, Ciesielska A, Wawer A, Sznejder-Pacholek A, Schwenkgrub J, Cudna A, Hadaczek P, Bankiewicz KS, Czlonkowska A, Czlonkowski A. The influence of AAV2-mediated gene transfer of human IL-10 on neurodegeneration and immune response in a murine model of Parkinson's disease. Pharmacol Rep. 2014;66:660-9.
-
(2014)
Pharmacol Rep
, vol.66
, pp. 660-669
-
-
Joniec-Maciejak, I.1
Ciesielska, A.2
Wawer, A.3
Sznejder-Pacholek, A.4
Schwenkgrub, J.5
Cudna, A.6
Hadaczek, P.7
Bankiewicz, K.S.8
Czlonkowska, A.9
Czlonkowski, A.10
-
72
-
-
65249119363
-
Powerful beneficial effects of macrophage colony-stimulating factor on beta-amyloid deposition and cognitive impairment in Alzheimer's disease
-
Boissonneault V, Filali M, Lessard M, Relton J, Wong G, Rivest S. Powerful beneficial effects of macrophage colony-stimulating factor on beta-amyloid deposition and cognitive impairment in Alzheimer's disease. Brain. 2009;132:1078-92.
-
(2009)
Brain
, vol.132
, pp. 1078-1092
-
-
Boissonneault, V.1
Filali, M.2
Lessard, M.3
Relton, J.4
Wong, G.5
Rivest, S.6
-
73
-
-
77954495173
-
IFN-gamma promotes complement expression and attenuates amyloid plaque deposition in amyloid beta precursor protein transgenic mice
-
Chakrabarty P, Ceballos-Diaz C, Beccard A, Janus C, Dickson D, Golde TE, Das P. IFN-gamma promotes complement expression and attenuates amyloid plaque deposition in amyloid beta precursor protein transgenic mice. J Immunol. 2010;184:5333-43.
-
(2010)
J Immunol
, vol.184
, pp. 5333-5343
-
-
Chakrabarty, P.1
Ceballos-Diaz, C.2
Beccard, A.3
Janus, C.4
Dickson, D.5
Golde, T.E.6
Das, P.7
-
74
-
-
79951551206
-
Hippocampal expression of murine TNFalpha results in attenuation of amyloid deposition in vivo
-
Chakrabarty P, Herring A, Ceballos-Diaz C, Das P, Golde TE. Hippocampal expression of murine TNFalpha results in attenuation of amyloid deposition in vivo. Mol Neurodegener. 2011;6:16.
-
(2011)
Mol Neurodegener
, vol.6
, pp. 16
-
-
Chakrabarty, P.1
Herring, A.2
Ceballos-Diaz, C.3
Das, P.4
Golde, T.E.5
-
75
-
-
34147115541
-
Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease
-
El Khoury J, Toft M, Hickman SE, Means TK, Terada K, Geula C, Luster AD. Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease. Nat Med. 2007;13:432-8.
-
(2007)
Nat Med
, vol.13
, pp. 432-438
-
-
Khoury, J.1
Toft, M.2
Hickman, S.E.3
Means, T.K.4
Terada, K.5
Geula, C.6
Luster, A.D.7
-
76
-
-
34247502763
-
Microglial activation is required for Abeta clearance after intracranial injection of lipopolysaccharide in APP transgenic mice
-
Herber DL, Mercer M, Roth LM, Symmonds K, Maloney J, Wilson N, Freeman MJ, Morgan D, Gordon MN. Microglial activation is required for Abeta clearance after intracranial injection of lipopolysaccharide in APP transgenic mice. J Neuroimmune Pharmacol. 2007;2:222-31.
-
(2007)
J Neuroimmune Pharmacol
, vol.2
, pp. 222-231
-
-
Herber, D.L.1
Mercer, M.2
Roth, L.M.3
Symmonds, K.4
Maloney, J.5
Wilson, N.6
Freeman, M.J.7
Morgan, D.8
Gordon, M.N.9
-
77
-
-
79955775349
-
CC chemokine receptor 2 deficiency aggravates cognitive impairments and amyloid pathology in a transgenic mouse model of Alzheimer's disease
-
Naert G, Rivest S. CC chemokine receptor 2 deficiency aggravates cognitive impairments and amyloid pathology in a transgenic mouse model of Alzheimer's disease. J Neurosci. 2011;31:6208-20.
-
(2011)
J Neurosci
, vol.31
, pp. 6208-6220
-
-
Naert, G.1
Rivest, S.2
-
78
-
-
34249899174
-
Sustained hippocampal IL-1 beta overexpression mediates chronic neuroinflammation and ameliorates Alzheimer plaque pathology
-
Shaftel SS, Kyrkanides S, Olschowka JA, Miller JN, Johnson RE, O'Banion MK. Sustained hippocampal IL-1 beta overexpression mediates chronic neuroinflammation and ameliorates Alzheimer plaque pathology. J Clin Invest. 2007;117:1595-604.
-
(2007)
J Clin Invest
, vol.117
, pp. 1595-1604
-
-
Shaftel, S.S.1
Kyrkanides, S.2
Olschowka, J.A.3
Miller, J.N.4
Johnson, R.E.5
O'Banion, M.K.6
-
79
-
-
84922064574
-
IL-10 alters immunoproteostasis in APP mice, increasing plaque burden and worsening cognitive behavior
-
Chakrabarty P, Li A, Ceballos-Diaz C, Eddy JA, Funk CC, Moore B, DiNunno N, Rosario AM, Cruz PE, Verbeeck C, et al. IL-10 alters immunoproteostasis in APP mice, increasing plaque burden and worsening cognitive behavior. Neuron. 2015;85:519-33.
-
(2015)
Neuron
, vol.85
, pp. 519-533
-
-
Chakrabarty, P.1
Li, A.2
Ceballos-Diaz, C.3
Eddy, J.A.4
Funk, C.C.5
Moore, B.6
DiNunno, N.7
Rosario, A.M.8
Cruz, P.E.9
Verbeeck, C.10
-
80
-
-
84922026428
-
Il10 deficiency rebalances innate immunity to mitigate Alzheimer-like pathology
-
Guillot-Sestier MV, Doty KR, Gate D, Rodriguez Jr J, Leung BP, Rezai-Zadeh K, Town T. Il10 deficiency rebalances innate immunity to mitigate Alzheimer-like pathology. Neuron. 2015;85:534-48.
-
(2015)
Neuron
, vol.85
, pp. 534-548
-
-
Guillot-Sestier, M.V.1
Doty, K.R.2
Gate, D.3
Rodriguez, J.4
Leung, B.P.5
Rezai-Zadeh, K.6
Town, T.7
-
81
-
-
78951484585
-
Lipopolysaccharide-stimulated interleukin-10 release from neonatal spinal cord microglia is potentiated by glutamate
-
Werry EL, Liu GJ, Lovelace MD, Nagarajah R, Hickie IB, Bennett MR. Lipopolysaccharide-stimulated interleukin-10 release from neonatal spinal cord microglia is potentiated by glutamate. Neuroscience. 2011;175:93-103.
-
(2011)
Neuroscience
, vol.175
, pp. 93-103
-
-
Werry, E.L.1
Liu, G.J.2
Lovelace, M.D.3
Nagarajah, R.4
Hickie, I.B.5
Bennett, M.R.6
-
82
-
-
68249159584
-
Glycogen synthase kinase-3 negatively regulates anti-inflammatory interleukin-10 for lipopolysaccharide-induced iNOS/NO biosynthesis and RANTES production in microglial cells
-
Huang WC, Lin YS, Wang CY, Tsai CC, Tseng HC, Chen CL, Lu PJ, Chen PS, Qian L, Hong JS, Lin CF. Glycogen synthase kinase-3 negatively regulates anti-inflammatory interleukin-10 for lipopolysaccharide-induced iNOS/NO biosynthesis and RANTES production in microglial cells. Immunology. 2009;128:e275-86.
-
(2009)
Immunology
, vol.128
-
-
Huang, W.C.1
Lin, Y.S.2
Wang, C.Y.3
Tsai, C.C.4
Tseng, H.C.5
Chen, C.L.6
Lu, P.J.7
Chen, P.S.8
Qian, L.9
Hong, J.S.10
Lin, C.F.11
-
83
-
-
4644232615
-
Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs
-
Olson JK, Miller SD. Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs. J Immunol. 2004;173:3916-24.
-
(2004)
J Immunol
, vol.173
, pp. 3916-3924
-
-
Olson, J.K.1
Miller, S.D.2
-
85
-
-
84855402336
-
Adenosine augments IL-10 production by microglial cells through an A2B adenosine receptor-mediated process
-
Koscso B, Csoka B, Selmeczy Z, Himer L, Pacher P, Virag L, Hasko G. Adenosine augments IL-10 production by microglial cells through an A2B adenosine receptor-mediated process. J Immunol. 2012;188:445-53.
-
(2012)
J Immunol
, vol.188
, pp. 445-453
-
-
Koscso, B.1
Csoka, B.2
Selmeczy, Z.3
Himer, L.4
Pacher, P.5
Virag, L.6
Hasko, G.7
-
86
-
-
2442718746
-
Interleukin-10 expression in lipopolysaccharide-activated microglia is mediated by extracellular ATP in an autocrine fashion
-
Seo DR, Kim KY, Lee YB. Interleukin-10 expression in lipopolysaccharide-activated microglia is mediated by extracellular ATP in an autocrine fashion. Neuroreport. 2004;15:1157-61.
-
(2004)
Neuroreport
, vol.15
, pp. 1157-1161
-
-
Seo, D.R.1
Kim, K.Y.2
Lee, Y.B.3
-
87
-
-
40449083110
-
Cross talk between P2 purinergic receptors modulates extracellular ATP-mediated interleukin-10 production in rat microglial cells
-
Seo DR, Kim SY, Kim KY, Lee HG, Moon JH, Lee JS, Lee SH, Kim SU, Lee YB. Cross talk between P2 purinergic receptors modulates extracellular ATP-mediated interleukin-10 production in rat microglial cells. Exp Mol Med. 2008;40:19-26.
-
(2008)
Exp Mol Med
, vol.40
, pp. 19-26
-
-
Seo, D.R.1
Kim, S.Y.2
Kim, K.Y.3
Lee, H.G.4
Moon, J.H.5
Lee, J.S.6
Lee, S.H.7
Kim, S.U.8
Lee, Y.B.9
-
88
-
-
0033564234
-
Opposite effects of interferon-gamma and prostaglandin E2 on tumor necrosis factor and interleukin-10 production in microglia: a regulatory loop controlling microglia pro- and anti-inflammatory activities
-
Aloisi F, De Simone R, Columba-Cabezas S, Levi G. Opposite effects of interferon-gamma and prostaglandin E2 on tumor necrosis factor and interleukin-10 production in microglia: a regulatory loop controlling microglia pro- and anti-inflammatory activities. J Neurosci Res. 1999;56:571-80.
-
(1999)
J Neurosci Res
, vol.56
, pp. 571-580
-
-
Aloisi, F.1
Simone, R.2
Columba-Cabezas, S.3
Levi, G.4
-
89
-
-
84923197617
-
Benfotiamine attenuates inflammatory response in LPS stimulated BV-2 microglia
-
Bozic I, Savic D, Laketa D, Bjelobaba I, Milenkovic I, Pekovic S, Nedeljkovic N, Lavrnja I. Benfotiamine attenuates inflammatory response in LPS stimulated BV-2 microglia. PLoS One. 2015;10:e0118372.
-
(2015)
PLoS One
, vol.10
-
-
Bozic, I.1
Savic, D.2
Laketa, D.3
Bjelobaba, I.4
Milenkovic, I.5
Pekovic, S.6
Nedeljkovic, N.7
Lavrnja, I.8
-
90
-
-
84893323756
-
Mycoepoxydiene inhibits activation of BV2 microglia stimulated by lipopolysaccharide through suppressing NF-kappaB, ERK 1/2 and toll-like receptor pathways
-
Su X, Chen Q, Chen W, Chen T, Li W, Li Y, Dou X, Zhang Y, Shen Y, Wu H, Yu C. Mycoepoxydiene inhibits activation of BV2 microglia stimulated by lipopolysaccharide through suppressing NF-kappaB, ERK 1/2 and toll-like receptor pathways. Int Immunopharmacol. 2014;19:88-93.
-
(2014)
Int Immunopharmacol
, vol.19
, pp. 88-93
-
-
Su, X.1
Chen, Q.2
Chen, W.3
Chen, T.4
Li, W.5
Li, Y.6
Dou, X.7
Zhang, Y.8
Shen, Y.9
Wu, H.10
Yu, C.11
-
91
-
-
73149113054
-
Anandamide enhances IL-10 production in activated microglia by targeting CB(2) receptors: roles of ERK1/2, JNK, and NF-kappaB
-
Correa F, Hernangomez M, Mestre L, Loria F, Spagnolo A, Docagne F, Di Marzo V, Guaza C. Anandamide enhances IL-10 production in activated microglia by targeting CB(2) receptors: roles of ERK1/2, JNK, and NF-kappaB. Glia. 2010;58:135-47.
-
(2010)
Glia
, vol.58
, pp. 135-147
-
-
Correa, F.1
Hernangomez, M.2
Mestre, L.3
Loria, F.4
Spagnolo, A.5
Docagne, F.6
Marzo, V.7
Guaza, C.8
-
92
-
-
3042513502
-
A new anti-inflammatory agent KL-1037 represses proinflammatory cytokine and inducible nitric oxide synthase (iNOS) gene expression in activated microglia
-
Kim WK, Jang PG, Woo MS, Han IO, Piao HZ, Lee K, Lee H, Joh TH, Kim HS. A new anti-inflammatory agent KL-1037 represses proinflammatory cytokine and inducible nitric oxide synthase (iNOS) gene expression in activated microglia. Neuropharmacology. 2004;47:243-52.
-
(2004)
Neuropharmacology
, vol.47
, pp. 243-252
-
-
Kim, W.K.1
Jang, P.G.2
Woo, M.S.3
Han, I.O.4
Piao, H.Z.5
Lee, K.6
Lee, H.7
Joh, T.H.8
Kim, H.S.9
-
93
-
-
77956615515
-
Activation of TNF receptor 2 in microglia promotes induction of anti-inflammatory pathways
-
Veroni C, Gabriele L, Canini I, Castiello L, Coccia E, Remoli ME, Columba-Cabezas S, Arico E, Aloisi F, Agresti C. Activation of TNF receptor 2 in microglia promotes induction of anti-inflammatory pathways. Mol Cell Neurosci. 2010;45:234-44.
-
(2010)
Mol Cell Neurosci
, vol.45
, pp. 234-244
-
-
Veroni, C.1
Gabriele, L.2
Canini, I.3
Castiello, L.4
Coccia, E.5
Remoli, M.E.6
Columba-Cabezas, S.7
Arico, E.8
Aloisi, F.9
Agresti, C.10
-
94
-
-
84881060258
-
ifn-gamma-dependent secretion of IL-10 from Th1 cells and microglia/macrophages contributes to functional recovery after spinal cord injury
-
Ishii H, Tanabe S, Ueno M, Kubo T, Kayama H, Serada S, Fujimoto M, Takeda K, Naka T, Yamashita T. ifn-gamma-dependent secretion of IL-10 from Th1 cells and microglia/macrophages contributes to functional recovery after spinal cord injury. Cell Death Dis. 2013;4:e710.
-
(2013)
Cell Death Dis
, vol.4
-
-
Ishii, H.1
Tanabe, S.2
Ueno, M.3
Kubo, T.4
Kayama, H.5
Serada, S.6
Fujimoto, M.7
Takeda, K.8
Naka, T.9
Yamashita, T.10
-
95
-
-
79955662810
-
Glatiramer acetate modulates TNF-alpha and IL-10 secretion in microglia and promotes their phagocytic activity
-
Pul R, Moharregh-Khiabani D, Skuljec J, Skripuletz T, Garde N, Voss EV, Stangel M. Glatiramer acetate modulates TNF-alpha and IL-10 secretion in microglia and promotes their phagocytic activity. J Neuroimmune Pharmacol. 2011;6:381-8.
-
(2011)
J Neuroimmune Pharmacol
, vol.6
, pp. 381-388
-
-
Pul, R.1
Moharregh-Khiabani, D.2
Skuljec, J.3
Skripuletz, T.4
Garde, N.5
Voss, E.V.6
Stangel, M.7
-
96
-
-
84908318166
-
Resveratrol induces the expression of interleukin-10 and brain-derived neurotrophic factor in BV2 microglia under hypoxia
-
Song J, Cheon SY, Jung W, Lee WT, Lee JE. Resveratrol induces the expression of interleukin-10 and brain-derived neurotrophic factor in BV2 microglia under hypoxia. Int J Mol Sci. 2014;15:15512-29.
-
(2014)
Int J Mol Sci
, vol.15
, pp. 15512-15529
-
-
Song, J.1
Cheon, S.Y.2
Jung, W.3
Lee, W.T.4
Lee, J.E.5
-
97
-
-
32344437590
-
TLR3-mediated signal induces proinflammatory cytokine and chemokine gene expression in astrocytes: differential signaling mechanisms of TLR3-induced IP-10 and IL-8 gene expression
-
Park C, Lee S, Cho IH, Lee HK, Kim D, Choi SY, Oh SB, Park K, Kim JS, Lee SJ. TLR3-mediated signal induces proinflammatory cytokine and chemokine gene expression in astrocytes: differential signaling mechanisms of TLR3-induced IP-10 and IL-8 gene expression. Glia. 2006;53:248-56.
-
(2006)
Glia
, vol.53
, pp. 248-256
-
-
Park, C.1
Lee, S.2
Cho, I.H.3
Lee, H.K.4
Kim, D.5
Choi, S.Y.6
Oh, S.B.7
Park, K.8
Kim, J.S.9
Lee, S.J.10
-
98
-
-
33646000807
-
Murine glia express the immunosuppressive cytokine, interleukin-10, following exposure to Borrelia burgdorferi or Neisseria meningitidis
-
Rasley A, Tranguch SL, Rati DM, Marriott I. Murine glia express the immunosuppressive cytokine, interleukin-10, following exposure to Borrelia burgdorferi or Neisseria meningitidis. Glia. 2006;53:583-92.
-
(2006)
Glia
, vol.53
, pp. 583-592
-
-
Rasley, A.1
Tranguch, S.L.2
Rati, D.M.3
Marriott, I.4
-
99
-
-
0034008833
-
HIV-1 envelope protein gp41 modulates expression of interleukin-10 and chemokine receptors on monocytes, astrocytes and neurones
-
Speth C, Joebstl B, Barcova M, Dierich MP. HIV-1 envelope protein gp41 modulates expression of interleukin-10 and chemokine receptors on monocytes, astrocytes and neurones. AIDS. 2000;14:629-36.
-
(2000)
AIDS
, vol.14
, pp. 629-636
-
-
Speth, C.1
Joebstl, B.2
Barcova, M.3
Dierich, M.P.4
-
100
-
-
20444434592
-
Modulation of the cytokine network in human adult astrocytes by human herpesvirus-6A
-
Meeuwsen S, Persoon-Deen C, Bsibsi M, Bajramovic JJ, Ravid R, De Bolle L, van Noort JM. Modulation of the cytokine network in human adult astrocytes by human herpesvirus-6A. J Neuroimmunol. 2005;164:37-47.
-
(2005)
J Neuroimmunol
, vol.164
, pp. 37-47
-
-
Meeuwsen, S.1
Persoon-Deen, C.2
Bsibsi, M.3
Bajramovic, J.J.4
Ravid, R.5
Bolle, L.6
Noort, J.M.7
-
101
-
-
27744562724
-
Involvement of TLR4/type I IL-1 receptor signaling in the induction of inflammatory mediators and cell death induced by ethanol in cultured astrocytes
-
Blanco AM, Valles SL, Pascual M, Guerri C. Involvement of TLR4/type I IL-1 receptor signaling in the induction of inflammatory mediators and cell death induced by ethanol in cultured astrocytes. J Immunol. 2005;175:6893-9.
-
(2005)
J Immunol
, vol.175
, pp. 6893-6899
-
-
Blanco, A.M.1
Valles, S.L.2
Pascual, M.3
Guerri, C.4
-
102
-
-
61349193143
-
Peripheral lipopolysaccharide (LPS) challenge promotes microglial hyperactivity in aged mice that is associated with exaggerated induction of both pro-inflammatory IL-1beta and anti-inflammatory IL-10 cytokines
-
Henry CJ, Huang Y, Wynne AM, Godbout JP. Peripheral lipopolysaccharide (LPS) challenge promotes microglial hyperactivity in aged mice that is associated with exaggerated induction of both pro-inflammatory IL-1beta and anti-inflammatory IL-10 cytokines. Brain Behav Immun. 2009;23:309-17.
-
(2009)
Brain Behav Immun
, vol.23
, pp. 309-317
-
-
Henry, C.J.1
Huang, Y.2
Wynne, A.M.3
Godbout, J.P.4
-
103
-
-
84861989218
-
Lipopolysaccharide-induced interleukin (IL)-4 receptor-alpha expression and corresponding sensitivity to the M2 promoting effects of IL-4 are impaired in microglia of aged mice
-
Fenn AM, Henry CJ, Huang Y, Dugan A, Godbout JP. Lipopolysaccharide-induced interleukin (IL)-4 receptor-alpha expression and corresponding sensitivity to the M2 promoting effects of IL-4 are impaired in microglia of aged mice. Brain Behav Immun. 2012;26:766-77.
-
(2012)
Brain Behav Immun
, vol.26
, pp. 766-777
-
-
Fenn, A.M.1
Henry, C.J.2
Huang, Y.3
Dugan, A.4
Godbout, J.P.5
-
104
-
-
65349085510
-
Interleukin-10 and interleukin-10 receptor-I are upregulated in glial cells after an excitotoxic injury to the postnatal rat brain
-
Gonzalez P, Burgaya F, Acarin L, Peluffo H, Castellano B, Gonzalez B. Interleukin-10 and interleukin-10 receptor-I are upregulated in glial cells after an excitotoxic injury to the postnatal rat brain. J Neuropathol Exp Neurol. 2009;68:391-403.
-
(2009)
J Neuropathol Exp Neurol
, vol.68
, pp. 391-403
-
-
Gonzalez, P.1
Burgaya, F.2
Acarin, L.3
Peluffo, H.4
Castellano, B.5
Gonzalez, B.6
-
106
-
-
0036544764
-
Cellular localization and expression patterns of interleukin-10, interleukin-4, and their receptors in multiple sclerosis lesions
-
Hulshof S, Montagne L, De Groot CJ, Van Der Valk P. Cellular localization and expression patterns of interleukin-10, interleukin-4, and their receptors in multiple sclerosis lesions. Glia. 2002;38:24-35.
-
(2002)
Glia
, vol.38
, pp. 24-35
-
-
Hulshof, S.1
Montagne, L.2
Groot, C.J.3
Valk, P.4
-
107
-
-
0037333298
-
Regional and temporal expression patterns of interleukin-10, interleukin-10 receptor and adhesion molecules in the rat spinal cord during chronic relapsing EAE
-
Ledeboer A, Wierinckx A, Bol JG, Floris S, Renardel de Lavalette C, De Vries HE, van den Berg TK, Dijkstra CD, Tilders FJ, Van Dam AM. Regional and temporal expression patterns of interleukin-10, interleukin-10 receptor and adhesion molecules in the rat spinal cord during chronic relapsing EAE. J Neuroimmunol. 2003;136:94-103.
-
(2003)
J Neuroimmunol
, vol.136
, pp. 94-103
-
-
Ledeboer, A.1
Wierinckx, A.2
Bol, J.G.3
Floris, S.4
Renardel de Lavalette, C.5
Vries, H.E.6
Berg, T.K.7
Dijkstra, C.D.8
Tilders, F.J.9
Van Dam, A.M.10
-
108
-
-
0031944696
-
Time course and cellular localization of interleukin-10 mRNA and protein expression in autoimmune inflammation of the rat central nervous system
-
Jander S, Pohl J, D'Urso D, Gillen C, Stoll G. Time course and cellular localization of interleukin-10 mRNA and protein expression in autoimmune inflammation of the rat central nervous system. Am J Pathol. 1998;152:975-82.
-
(1998)
Am J Pathol
, vol.152
, pp. 975-982
-
-
Jander, S.1
Pohl, J.2
D'Urso, D.3
Gillen, C.4
Stoll, G.5
-
109
-
-
84880038556
-
High interleukin-10 expression within the central nervous system may be important for initiation of recovery of Dark Agouti rats from experimental autoimmune encephalomyelitis
-
Blazevski J, Petkovic F, Momcilovic M, Jevtic B, Miljkovic D, Mostarica SM. High interleukin-10 expression within the central nervous system may be important for initiation of recovery of Dark Agouti rats from experimental autoimmune encephalomyelitis. Immunobiology. 2013;218:1192-9.
-
(2013)
Immunobiology
, vol.218
, pp. 1192-1199
-
-
Blazevski, J.1
Petkovic, F.2
Momcilovic, M.3
Jevtic, B.4
Miljkovic, D.5
Mostarica, S.M.6
-
110
-
-
0030703663
-
Gene expression of IL-10 in relationship to TNF-alpha, IL-1beta and IL-2 in the rat brain following middle cerebral artery occlusion
-
Zhai QH, Futrell N, Chen FJ. Gene expression of IL-10 in relationship to TNF-alpha, IL-1beta and IL-2 in the rat brain following middle cerebral artery occlusion. J Neurol Sci. 1997;152:119-24.
-
(1997)
J Neurol Sci
, vol.152
, pp. 119-124
-
-
Zhai, Q.H.1
Futrell, N.2
Chen, F.J.3
-
111
-
-
33646083015
-
The effect of traumatic brain injury upon the concentration and expression of interleukin-1beta and interleukin-10 in the rat
-
Kamm K, Vanderkolk W, Lawrence C, Jonker M, Davis AT. The effect of traumatic brain injury upon the concentration and expression of interleukin-1beta and interleukin-10 in the rat. J Trauma. 2006;60:152-7.
-
(2006)
J Trauma
, vol.60
, pp. 152-157
-
-
Kamm, K.1
Vanderkolk, W.2
Lawrence, C.3
Jonker, M.4
Davis, A.T.5
-
112
-
-
0035831189
-
Beta-amyloid-induced glial expression of both pro- and anti-inflammatory cytokines in cerebral cortex of aged transgenic Tg2576 mice with Alzheimer plaque pathology
-
Apelt J, Schliebs R. Beta-amyloid-induced glial expression of both pro- and anti-inflammatory cytokines in cerebral cortex of aged transgenic Tg2576 mice with Alzheimer plaque pathology. Brain Res. 2001;894:21-30.
-
(2001)
Brain Res
, vol.894
, pp. 21-30
-
-
Apelt, J.1
Schliebs, R.2
-
113
-
-
64549093797
-
Circulating interleukin-10 and interleukin-12 in Parkinson's disease
-
Rentzos M, Nikolaou C, Andreadou E, Paraskevas GP, Rombos A, Zoga M, Tsoutsou A, Boufidou F, Kapaki E, Vassilopoulos D. Circulating interleukin-10 and interleukin-12 in Parkinson's disease. Acta Neurol Scand. 2009;119:332-7.
-
(2009)
Acta Neurol Scand
, vol.119
, pp. 332-337
-
-
Rentzos, M.1
Nikolaou, C.2
Andreadou, E.3
Paraskevas, G.P.4
Rombos, A.5
Zoga, M.6
Tsoutsou, A.7
Boufidou, F.8
Kapaki, E.9
Vassilopoulos, D.10
-
114
-
-
45849105153
-
Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease
-
Jin JJ, Kim HD, Maxwell JA, Li L, Fukuchi K. Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease. J Neuroinflammation. 2008;5:23.
-
(2008)
J Neuroinflammation
, vol.5
, pp. 23
-
-
Jin, J.J.1
Kim, H.D.2
Maxwell, J.A.3
Li, L.4
Fukuchi, K.5
-
115
-
-
84878115912
-
Neuroprotective effect of atorvastatin involves suppression of TNF-alpha and upregulation of IL-10 in a rat model of intracerebral hemorrhage
-
Ewen T, Qiuting L, Chaogang T, Tao T, Jun W, Liming T, Guanghong X. Neuroprotective effect of atorvastatin involves suppression of TNF-alpha and upregulation of IL-10 in a rat model of intracerebral hemorrhage. Cell Biochem Biophys. 2013;66:337-46.
-
(2013)
Cell Biochem Biophys
, vol.66
, pp. 337-346
-
-
Ewen, T.1
Qiuting, L.2
Chaogang, T.3
Tao, T.4
Jun, W.5
Liming, T.6
Guanghong, X.7
-
116
-
-
84906934110
-
Neuroimmune regulation of microglial activity involved in neuroinflammation and neurodegenerative diseases
-
Gonzalez H, Elgueta D, Montoya A, Pacheco R. Neuroimmune regulation of microglial activity involved in neuroinflammation and neurodegenerative diseases. J Neuroimmunol. 2014;274:1-13.
-
(2014)
J Neuroimmunol
, vol.274
, pp. 1-13
-
-
Gonzalez, H.1
Elgueta, D.2
Montoya, A.3
Pacheco, R.4
-
117
-
-
84962295744
-
Chromatin remodeling effects on enhancer activity
-
Garcia-Gonzalez E, Escamilla-Del-Arenal M, Arzate-Mejia R, Recillas-Targa F. Chromatin remodeling effects on enhancer activity. Cell Mol Life Sci. 2016;73(15):2897-910.
-
(2016)
Cell Mol Life Sci
, vol.73
, Issue.15
, pp. 2897-2910
-
-
Garcia-Gonzalez, E.1
Escamilla-Del-Arenal, M.2
Arzate-Mejia, R.3
Recillas-Targa, F.4
-
118
-
-
0035839136
-
Translating the histone code
-
Jenuwein T, Allis CD. Translating the histone code. Science. 2001;293:1074-80.
-
(2001)
Science
, vol.293
, pp. 1074-1080
-
-
Jenuwein, T.1
Allis, C.D.2
-
119
-
-
83055169214
-
Early-life experience decreases drug-induced reinstatement of morphine CPP in adulthood via microglial-specific epigenetic programming of anti-inflammatory IL-10 expression
-
Schwarz JM, Hutchinson MR, Bilbo SD. Early-life experience decreases drug-induced reinstatement of morphine CPP in adulthood via microglial-specific epigenetic programming of anti-inflammatory IL-10 expression. J Neurosci. 2011;31:17835-47.
-
(2011)
J Neurosci
, vol.31
, pp. 17835-17847
-
-
Schwarz, J.M.1
Hutchinson, M.R.2
Bilbo, S.D.3
-
120
-
-
79954937143
-
The endocannabinoid anandamide downregulates IL-23 and IL-12 subunits in a viral model of multiple sclerosis: evidence for a cross-talk between IL-12p70/IL-23 axis and IL-10 in microglial cells
-
Correa F, Hernangomez-Herrero M, Mestre L, Loria F, Docagne F, Guaza C. The endocannabinoid anandamide downregulates IL-23 and IL-12 subunits in a viral model of multiple sclerosis: evidence for a cross-talk between IL-12p70/IL-23 axis and IL-10 in microglial cells. Brain Behav Immun. 2011;25:736-49.
-
(2011)
Brain Behav Immun
, vol.25
, pp. 736-749
-
-
Correa, F.1
Hernangomez-Herrero, M.2
Mestre, L.3
Loria, F.4
Docagne, F.5
Guaza, C.6
-
121
-
-
80054902517
-
Differential roles of PKA and Epac on the production of cytokines in the endotoxin-stimulated primary cultured microglia
-
Liu J, Zhao X, Cao J, Xue Q, Feng X, Liu X, Zhang F, Yu B. Differential roles of PKA and Epac on the production of cytokines in the endotoxin-stimulated primary cultured microglia. J Mol Neurosci. 2011;45:186-93.
-
(2011)
J Mol Neurosci
, vol.45
, pp. 186-193
-
-
Liu, J.1
Zhao, X.2
Cao, J.3
Xue, Q.4
Feng, X.5
Liu, X.6
Zhang, F.7
Yu, B.8
-
122
-
-
59349083363
-
Alterations of Fc gamma receptor I and Toll-like receptor 4 mediate the antiinflammatory actions of microglia and astrocytes after adrenaline-induced blood-brain barrier opening in rats
-
Li YN, Qin XJ, Kuang F, Wu R, Duan XL, Ju G, Wang BR. Alterations of Fc gamma receptor I and Toll-like receptor 4 mediate the antiinflammatory actions of microglia and astrocytes after adrenaline-induced blood-brain barrier opening in rats. J Neurosci Res. 2008;86:3556-65.
-
(2008)
J Neurosci Res
, vol.86
, pp. 3556-3565
-
-
Li, Y.N.1
Qin, X.J.2
Kuang, F.3
Wu, R.4
Duan, X.L.5
Ju, G.6
Wang, B.R.7
-
123
-
-
84924225509
-
Transcription factor myocyte enhancer factor 2D regulates interleukin-10 production in microglia to protect neuronal cells from inflammation-induced death
-
Yang S, Gao L, Lu F, Wang B, Gao F, Zhu G, Cai Z, Lai J, Yang Q. Transcription factor myocyte enhancer factor 2D regulates interleukin-10 production in microglia to protect neuronal cells from inflammation-induced death. J Neuroinflammation. 2015;12:33.
-
(2015)
J Neuroinflammation
, vol.12
, pp. 33
-
-
Yang, S.1
Gao, L.2
Lu, F.3
Wang, B.4
Gao, F.5
Zhu, G.6
Cai, Z.7
Lai, J.8
Yang, Q.9
-
124
-
-
84875781795
-
Post-transcriptional regulatory networks in immunity
-
Ivanov P, Anderson P. Post-transcriptional regulatory networks in immunity. Immunol Rev. 2013;253:253-72.
-
(2013)
Immunol Rev
, vol.253
, pp. 253-272
-
-
Ivanov, P.1
Anderson, P.2
-
125
-
-
84876551248
-
PNA-based microRNA inhibitors elicit anti-inflammatory effects in microglia cells
-
Brown PN, Yin H. PNA-based microRNA inhibitors elicit anti-inflammatory effects in microglia cells. Chem Commun (Camb). 2013;49:4415-7.
-
(2013)
Chem Commun (Camb)
, vol.49
, pp. 4415-4417
-
-
Brown, P.N.1
Yin, H.2
-
126
-
-
84879604742
-
Evidence for miR-181 involvement in neuroinflammatory responses of astrocytes
-
Hutchison ER, Kawamoto EM, Taub DD, Lal A, Abdelmohsen K, Zhang Y, Wood 3rd WH, Lehrmann E, Camandola S, Becker KG, et al. Evidence for miR-181 involvement in neuroinflammatory responses of astrocytes. Glia. 2013;61:1018-28.
-
(2013)
Glia
, vol.61
, pp. 1018-1028
-
-
Hutchison, E.R.1
Kawamoto, E.M.2
Taub, D.D.3
Lal, A.4
Abdelmohsen, K.5
Zhang, Y.6
Wood, W.H.7
Lehrmann, E.8
Camandola, S.9
Becker, K.G.10
-
127
-
-
84866494960
-
GSK-3 mediates the release of IL-1beta, TNF-alpha and IL-10 from cortical glia
-
Green HF, Nolan YM. GSK-3 mediates the release of IL-1beta, TNF-alpha and IL-10 from cortical glia. Neurochem Int. 2012;61:666-71.
-
(2012)
Neurochem Int
, vol.61
, pp. 666-671
-
-
Green, H.F.1
Nolan, Y.M.2
-
128
-
-
84948845931
-
Glycogen synthase kinase 3 is part of the molecular machinery regulating the adaptive response to LPS stimulation in microglial cells
-
Ajmone-Cat MA, D'Urso MC, di Blasio G, Brignone MS, De Simone R, Minghetti L. Glycogen synthase kinase 3 is part of the molecular machinery regulating the adaptive response to LPS stimulation in microglial cells. Brain Behav Immun. 2016;55:225-35.
-
(2016)
Brain Behav Immun
, vol.55
, pp. 225-235
-
-
Ajmone-Cat, M.A.1
D'Urso, M.C.2
Blasio, G.3
Brignone, M.S.4
Simone, R.5
Minghetti, L.6
|