Early-life experience decreases drug-induced reinstatement of morphine CPP in adulthood via microglial-specific epigenetic programming of anti-inflammatory IL-10 expression

Journal of Neuroscience

Volumn 31, Issue 49, 2011, Pages 17835-17847

  Schwarz, Jaclyn M ^a   Hutchinson, Mark R ^b   Bilbo, Staci D ^a  

^a DUKE UNIVERSITY   (United States)

^b UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; CORTICOSTERONE; FRACTALKINE; GLIAL FIBRILLARY ACIDIC PROTEIN; IBUDILAST; INTERLEUKIN 10; INTERLEUKIN 1BETA; MORPHINE; NALOXONE;

ADULTHOOD; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COLORIMETRY; CONTINUOUS INFUSION; CONTROLLED STUDY; EARLY LIFE STRESS; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION; HOT PLATE TEST; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MICROGLIA; MICROSCOPY; NONHUMAN; NUCLEUS ACCUMBENS; PLACE PREFERENCE; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; ANTIGENS, CD11B; CHROMATOGRAPHY, LIQUID; CONDITIONING, OPERANT; CORTICOSTERONE; DRUG-SEEKING BEHAVIOR; EPIGENOMICS; EXTINCTION, PSYCHOLOGICAL; FEMALE; GENE EXPRESSION REGULATION; GLIAL FIBRILLARY ACIDIC PROTEIN; HANDLING (PSYCHOLOGY); IMMUNOPRECIPITATION; INTERLEUKIN-10; LIFE CHANGE EVENTS; MALE; MASS SPECTROMETRY; MICROGLIA; MICROINJECTIONS; MORPHINE; NALOXONE; NARCOTIC ANTAGONISTS; NARCOTICS; NUCLEUS ACCUMBENS; RATS; RATS, SPRAGUE-DAWLEY; REINFORCEMENT (PSYCHOLOGY);

EID: 83055169214     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3297-11.2011     Document Type: Article

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