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Volumn 56, Issue 6, 1999, Pages 571-580

Opposite effects of interferon-γ and prostaglandin E2 on tumor necrosis factor and interleukin-10 production in microglia: A regulatory loop controlling microglia pro- and anti-inflammatory activities

Author keywords

Central nervous system; Cytokines; Glia; Inflammation; Prostanoids

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; ISOPRENALINE; LIPOPOLYSACCHARIDE; MESSENGER RNA; PROSTAGLANDIN E2; PROSTAGLANDIN RECEPTOR; RECOMBINANT CYTOKINE; RECOMBINANT GAMMA INTERFERON; RECOMBINANT INTERLEUKIN 10; RECOMBINANT TUMOR NECROSIS FACTOR;

EID: 0033564234     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19990615)56:6<571::AID-JNR3>3.0.CO;2-P     Document Type: Article
Times cited : (123)

References (56)
  • 1
    • 0031571317 scopus 로고    scopus 로고
    • IL-12 production by central nervous system microglia is inhibited by astrocytes
    • Aloisi F, Penna, G, Cerase J, Menèndez Iglesias B, Adorini L. 1997. IL-12 production by central nervous system microglia is inhibited by astrocytes. J Immunol 159:1604-1612.
    • (1997) J Immunol , vol.159 , pp. 1604-1612
    • Aloisi, F.1    Penna, G.2    Cerase, J.3    Menèndez Iglesias, B.4    Adorini, L.5
  • 2
    • 0032524997 scopus 로고    scopus 로고
    • Microglia are more efficient than astrocytes in antigen processing and in Th1 but not Th2 cell activation
    • Aloisi F, Ria F, Penna G, Adorini L. 1998. Microglia are more efficient than astrocytes in antigen processing and in Th1 but not Th2 cell activation. J Immunol 160:4671-4680.
    • (1998) J Immunol , vol.160 , pp. 4671-4680
    • Aloisi, F.1    Ria, F.2    Penna, G.3    Adorini, L.4
  • 3
    • 9244260503 scopus 로고    scopus 로고
    • Attenuation of astroglial reactivity by interleukin-10
    • Balasingam V, Yong VW. 1996. Attenuation of astroglial reactivity by interleukin-10. J Neurosci 16:2945-2955.
    • (1996) J Neurosci , vol.16 , pp. 2945-2955
    • Balasingam, V.1    Yong, V.W.2
  • 4
    • 0030663981 scopus 로고    scopus 로고
    • Cytokines: Influence on glial cell gene expression and function
    • Benveniste EN. 1997. Cytokines: influence on glial cell gene expression and function. Chem Immunol 69:31-75.
    • (1997) Chem Immunol , vol.69 , pp. 31-75
    • Benveniste, E.N.1
  • 5
    • 0032193696 scopus 로고    scopus 로고
    • IL-10 is critical in the regulation of autoimune encephalomyelitis as demonstrated by studies of IL-10- and IL-4-deficient and transgenic mice
    • Bettelli E, Das MP, Howard ED, Weiner HL, Sobel RA, Kuchroo VK. 1998. IL-10 is critical in the regulation of autoimune encephalomyelitis as demonstrated by studies of IL-10-and IL-4-deficient and transgenic mice. J Immunol 161:3299-3306.
    • (1998) J Immunol , vol.161 , pp. 3299-3306
    • Bettelli, E.1    Das, M.P.2    Howard, E.D.3    Weiner, H.L.4    Sobel, R.A.5    Kuchroo, V.K.6
  • 7
    • 0027248910 scopus 로고
    • Modulation of macrophage function by transforming growth factorβ, interleukin-4, and interleukin-10
    • Bogdan C, Nathan C. 1993. Modulation of macrophage function by transforming growth factorβ, interleukin-4, and interleukin-10. Ann NY Acad Sci 685:713-739.
    • (1993) Ann NY Acad Sci , vol.685 , pp. 713-739
    • Bogdan, C.1    Nathan, C.2
  • 8
    • 0031596838 scopus 로고    scopus 로고
    • Prostaglandin E2 and 4-aminopyridine prevent the lipopolysaccharide-induced outwardly rectifying potassium current and interleukin-1 beta production in cultured rat microglia
    • Caggiano AO, Kraig RP. 1998. Prostaglandin E2 and 4-aminopyridine prevent the lipopolysaccharide-induced outwardly rectifying potassium current and interleukin-1 beta production in cultured rat microglia. J Neurochem 70:2357-2368.
    • (1998) J Neurochem , vol.70 , pp. 2357-2368
    • Caggiano, A.O.1    Kraig, R.P.2
  • 9
    • 0026738695 scopus 로고
    • Activated microglia mediate neuronal cell injury via a nitric oxide mechanism
    • Chao CC, Hu S, Molitor TW, Shaskan EG, Peterson PK. 1992. Activated microglia mediate neuronal cell injury via a nitric oxide mechanism. J Immunol 149:2736-2741.
    • (1992) J Immunol , vol.149 , pp. 2736-2741
    • Chao, C.C.1    Hu, S.2    Molitor, T.W.3    Shaskan, E.G.4    Peterson, P.K.5
  • 10
    • 0029078126 scopus 로고
    • Tumor necrosis factor-alpha production by human fetal microglial cells: Regulation by other cytokines
    • Chao CC, Hu S, Sheng WS, Peterson PK. 1995. Tumor necrosis factor-alpha production by human fetal microglial cells: regulation by other cytokines. Dev Neurosci 17:97-105.
    • (1995) Dev Neurosci , vol.17 , pp. 97-105
    • Chao, C.C.1    Hu, S.2    Sheng, W.S.3    Peterson, P.K.4
  • 11
    • 0018639079 scopus 로고
    • Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
    • Chirgwin M, Przybyla AE, Mac Donald RJ, Rutter WT. 1979. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 18:5294-5299.
    • (1979) Biochemistry , vol.18 , pp. 5294-5299
    • Chirgwin, M.1    Przybyla, A.E.2    Mac Donald, R.J.3    Rutter, W.T.4
  • 12
    • 0028658439 scopus 로고
    • Induction of superoxide anion and nitric oxide production in cultured microglia
    • Colton CA, Snell J, Chernyshev O, Gilbert DL. 1994. Induction of superoxide anion and nitric oxide production in cultured microglia. Ann NY Acad Sci 738:54-63.
    • (1994) Ann NY Acad Sci , vol.738 , pp. 54-63
    • Colton, C.A.1    Snell, J.2    Chernyshev, O.3    Gilbert, D.L.4
  • 13
    • 0028006939 scopus 로고
    • Extracellular human T-cell lymphotropic virus type i tax protein induces cytokine production in adult human microglial cells
    • Dhib-Jalbut S, Hoffman PM, Yamabe T, Sun D, Xia J, Eisenberg H, Bergey G, Ruscetti FW. 1994. Extracellular human T-cell lymphotropic virus type I tax protein induces cytokine production in adult human microglial cells. Ann Neurol 36:787-790.
    • (1994) Ann Neurol , vol.36 , pp. 787-790
    • Dhib-Jalbut, S.1    Hoffman, P.M.2    Yamabe, T.3    Sun, D.4    Xia, J.5    Eisenberg, H.6    Bergey, G.7    Ruscetti, F.W.8
  • 14
    • 0028316917 scopus 로고
    • Interferon γ upregulates its own expression in mouse peritoneal macrophages
    • Di Marzio P, Puddu P, Conti L, Belardelli F, Gessani S. 1994. Interferon γ upregulates its own expression in mouse peritoneal macrophages. J Exp Med 179:1731-1736.
    • (1994) J Exp Med , vol.179 , pp. 1731-1736
    • Di Marzio, P.1    Puddu, P.2    Conti, L.3    Belardelli, F.4    Gessani, S.5
  • 15
  • 16
    • 0029112744 scopus 로고
    • Inhibition of IL-10 expression by IFN-γ up-regulates transcription of TNF-α in human monocytes
    • Donnelly RP, Freeman SL, Hayes MP. 1995. Inhibition of IL-10 expression by IFN-γ up-regulates transcription of TNF-α in human monocytes. J Immunol 155:1420-1427.
    • (1995) J Immunol , vol.155 , pp. 1420-1427
    • Donnelly, R.P.1    Freeman, S.L.2    Hayes, M.P.3
  • 18
    • 0023618311 scopus 로고
    • Antigen presentation and tumor cytotoxicity by interferon-γ-treated microglial cells
    • Frei K, Siepl C, Groscurth P, Bodmer S, Schwerdel C, Fontana A. 1987. Antigen presentation and tumor cytotoxicity by interferon-γ-treated microglial cells. Eur J Immunol 17:1271-1278.
    • (1987) Eur J Immunol , vol.17 , pp. 1271-1278
    • Frei, K.1    Siepl, C.2    Groscurth, P.3    Bodmer, S.4    Schwerdel, C.5    Fontana, A.6
  • 19
    • 0028215961 scopus 로고
    • Antigen presentation in the central nervous system. The inhibitory effect of IL-10 on MHC class II expression and cytokine production depends on the inducing signals and the type of cell analyzed
    • Frei K, Lins H, Schwerdel C, Fontana A. 1994. Antigen presentation in the central nervous system. The inhibitory effect of IL-10 on MHC class II expression and cytokine production depends on the inducing signals and the type of cell analyzed. J Immunol 152:2720-2728.
    • (1994) J Immunol , vol.152 , pp. 2720-2728
    • Frei, K.1    Lins, H.2    Schwerdel, C.3    Fontana, A.4
  • 20
    • 0026574086 scopus 로고
    • Potential role of prostaglandins and leukotrienes in multiple sclerosis and experimental allergic encephalomyelitis
    • Fretland DJ. 1992. Potential role of prostaglandins and leukotrienes in multiple sclerosis and experimental allergic encephalomyelitis. Prostaglandins Leukotrienes Essential Fatty Acids 45:249-257.
    • (1992) Prostaglandins Leukotrienes Essential Fatty Acids , vol.45 , pp. 249-257
    • Fretland, D.J.1
  • 21
    • 0001352432 scopus 로고
    • Microglia and diseases of the nervous system
    • Giulian D. 1992. Microglia and diseases of the nervous system. Curr Neurol 12:23-54.
    • (1992) Curr Neurol , vol.12 , pp. 23-54
    • Giulian, D.1
  • 23
    • 0025860963 scopus 로고
    • Modulation of interleukin-1 and tumor necrosis factor expression by β-adrenergic agonists in mouse ameboid microglial cells
    • Hetier E, Ayala J, Bousseau A, Prochiantz A. 1991. Modulation of interleukin-1 and tumor necrosis factor expression by β-adrenergic agonists in mouse ameboid microglial cells. Exp Brain Res 86:407-413.
    • (1991) Exp Brain Res , vol.86 , pp. 407-413
    • Hetier, E.1    Ayala, J.2    Bousseau, A.3    Prochiantz, A.4
  • 24
    • 0028806468 scopus 로고
    • Cytokine production in the central nervous system of Lewis rats with experimental autoimmune encephalomyelitis: Dynamics of mRNA expression for interleukin-10, interleukin-12, tumor necrosis factor α and tumor necrosis factor β
    • Issazadeh S, Ljungdahl Å, Hojeberg B, Mustafa M, Olsson T. 1995. Cytokine production in the central nervous system of Lewis rats with experimental autoimmune encephalomyelitis: dynamics of mRNA expression for interleukin-10, interleukin-12, tumor necrosis factor α and tumor necrosis factor β. J Neuroimmunol 61:205-212.
    • (1995) J Neuroimmunol , vol.61 , pp. 205-212
    • Issazadeh, S.1    Ljungdahl, Å.2    Hojeberg, B.3    Mustafa, M.4    Olsson, T.5
  • 25
    • 0031944696 scopus 로고    scopus 로고
    • Time course and cellular localization of interleukin-10 mRNA and protein expresion in autoimmune inflammation of the rat central nervous system
    • Jander S, Pohl J, D'Urso D, Gillen C, Stoll G. 1998. Time course and cellular localization of interleukin-10 mRNA and protein expresion in autoimmune inflammation of the rat central nervous system. Am J Pathol 152:975-982.
    • (1998) Am J Pathol , vol.152 , pp. 975-982
    • Jander, S.1    Pohl, J.2    D'Urso, D.3    Gillen, C.4    Stoll, G.5
  • 26
    • 0023938335 scopus 로고
    • The adenylate cyclase-cAMP-protein kinase a pathway and regulation of the immune response
    • Kammer GM. 1988. The adenylate cyclase-cAMP-protein kinase A pathway and regulation of the immune response. Immunol Today 9:222-229.
    • (1988) Immunol Today , vol.9 , pp. 222-229
    • Kammer, G.M.1
  • 27
    • 0026707402 scopus 로고
    • Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery
    • Kennedy MK, Torrance DS, Picha KS, Mohler KM. 1992. Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery. J Immunol 149:2496-2505.
    • (1992) J Immunol , vol.149 , pp. 2496-2505
    • Kennedy, M.K.1    Torrance, D.S.2    Picha, K.S.3    Mohler, K.M.4
  • 28
    • 0026713026 scopus 로고
    • Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor β, inlerleukin 4, and prostaglandin E expression in the brain
    • Khoury SJ, Hancock WW, Weiner HL. 1994. Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor β, inlerleukin 4, and prostaglandin E expression in the brain. J Exp Med 176:1355-1364.
    • (1994) J Exp Med , vol.176 , pp. 1355-1364
    • Khoury, S.J.1    Hancock, W.W.2    Weiner, H.L.3
  • 29
    • 0038917435 scopus 로고    scopus 로고
    • Critical points of tumor necrosis factor action in central nervous system autoimmune inflammation defined by gene targeting
    • Körner H, Riminton DS, Strickland DH, Lemckert FA, Pollard JD, Sedgwick JD. 1997. Critical points of tumor necrosis factor action in central nervous system autoimmune inflammation defined by gene targeting. J Exp Med 186:1585-1590.
    • (1997) J Exp Med , vol.186 , pp. 1585-1590
    • Körner, H.1    Riminton, D.S.2    Strickland, D.H.3    Lemckert, F.A.4    Pollard, J.D.5    Sedgwick, J.D.6
  • 30
    • 0030222037 scopus 로고    scopus 로고
    • Microglia: A sensor for pathological events in the CNS
    • Kreutzberg GW. 1996. Microglia: a sensor for pathological events in the CNS. Trends Neurosci 19:312-318.
    • (1996) Trends Neurosci , vol.19 , pp. 312-318
    • Kreutzberg, G.W.1
  • 31
    • 0031054724 scopus 로고    scopus 로고
    • Cellular signaling roles of TGF beta, TNF alpha and beta APP in brain injury responses and Alzheimer's disease
    • Mattson MP, Barger SW, Furukawa K, Bruce AJ, Wyss-Coray T, Mark RJ, Mucke L. 1997. Cellular signaling roles of TGF beta, TNF alpha and beta APP in brain injury responses and Alzheimer's disease. Brain Res Rev 23:47-61.
    • (1997) Brain Res Rev , vol.23 , pp. 47-61
    • Mattson, M.P.1    Barger, S.W.2    Furukawa, K.3    Bruce, A.J.4    Wyss-Coray, T.5    Mark, R.J.6    Mucke, L.7
  • 33
    • 0030221758 scopus 로고    scopus 로고
    • Cytokines in inflammatory brain lesions: Helpful and harmful
    • Merrill JE, Benveniste EN. 1996. Cytokines in inflammatory brain lesions: helpful and harmful. Trends Neurosci 19:331-338.
    • (1996) Trends Neurosci , vol.19 , pp. 331-338
    • Merrill, J.E.1    Benveniste, E.N.2
  • 34
    • 0031985513 scopus 로고    scopus 로고
    • Microglia as effector cells in brain damage and repair: Focus on prostanoids and nitric oxide
    • Minghetti L, Levi G. 1998. Microglia as effector cells in brain damage and repair: focus on prostanoids and nitric oxide. Progr Neurobiol 54:99-125.
    • (1998) Progr Neurobiol , vol.54 , pp. 99-125
    • Minghetti, L.1    Levi, G.2
  • 35
    • 0029961125 scopus 로고    scopus 로고
    • Interferon-γ and nitric oxide down-regulate lipopolysaccharide-induced prostanoid production in cultured rat microglial cells by inhibiting cyclooxygenase-2 expression
    • Minghetti L, Polazzi E, Nicolini A, Créminon C, Levi G. 1996. Interferon-γ and nitric oxide down-regulate lipopolysaccharide-induced prostanoid production in cultured rat microglial cells by inhibiting cyclooxygenase-2 expression. J Neurochem 66:1963-1970.
    • (1996) J Neurochem , vol.66 , pp. 1963-1970
    • Minghetti, L.1    Polazzi, E.2    Nicolini, A.3    Créminon, C.4    Levi, G.5
  • 36
    • 0030994412 scopus 로고    scopus 로고
    • Up-regulation of cyclooxygenase-2 expression in cultured microglia by prostaglandin-E2, cyclic AMP and non-steroidal anti-inflammatory drugs
    • Minghetti L, Polazzi E, Nicolini A, Créminon C, Levi G. 1997. Up-regulation of cyclooxygenase-2 expression in cultured microglia by prostaglandin-E2, cyclic AMP and non-steroidal anti-inflammatory drugs. Eur J Neurosci 9:934-940.
    • (1997) Eur J Neurosci , vol.9 , pp. 934-940
    • Minghetti, L.1    Polazzi, E.2    Nicolini, A.3    Créminon, C.4    Levi, G.5
  • 38
    • 0027324733 scopus 로고
    • Detection of in vivo expression of interleukin-10 using a semi-quantitative polymerase chain reaction method in Schistosoma mansoni infected mice
    • Murphy E, Hieny S, Sher A, O'Garra A. 1993. Detection of in vivo expression of interleukin-10 using a semi-quantitative polymerase chain reaction method in Schistosoma mansoni infected mice. J Immunol Methods 162:211-223.
    • (1993) J Immunol Methods , vol.162 , pp. 211-223
    • Murphy, E.1    Hieny, S.2    Sher, A.3    O'Garra, A.4
  • 39
    • 0032510798 scopus 로고    scopus 로고
    • Neurotrophins inhibit major histocompatibility class II inducibility of microglia: Involvement of the p75 neurotrophin receptor
    • Neumann H, Misgeld T, Matsumuro K, Wekerle H. 1998. Neurotrophins inhibit major histocompatibility class II inducibility of microglia: involvement of the p75 neurotrophin receptor. Proc Natl Acad Sci USA 95:5779-5784.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 5779-5784
    • Neumann, H.1    Misgeld, T.2    Matsumuro, K.3    Wekerle, H.4
  • 40
    • 0028990468 scopus 로고
    • Critical influences of the cytokine orchestration on the outcome of myelin antigen-specific T-cell autoimmunity in experimental autoimmune encephalomyelitis and multiple sclerosis
    • Olsson T. 1995. Critical influences of the cytokine orchestration on the outcome of myelin antigen-specific T-cell autoimmunity in experimental autoimmune encephalomyelitis and multiple sclerosis. Immunol Rev 144:245-268.
    • (1995) Immunol Rev , vol.144 , pp. 245-268
    • Olsson, T.1
  • 41
    • 0029310632 scopus 로고    scopus 로고
    • Interferon-γ and lipopolysaccharide reduce cAMP responses in cultured glial cells: Reversal by a type IV phosphodiesterase inhibitor
    • Patrizio M, Costa T, Levi G. 1996. Interferon-γ and lipopolysaccharide reduce cAMP responses in cultured glial cells: reversal by a type IV phosphodiesterase inhibitor. Glia 14:94-100.
    • (1996) Glia , vol.14 , pp. 94-100
    • Patrizio, M.1    Costa, T.2    Levi, G.3
  • 42
    • 0028957419 scopus 로고
    • Up-regulation of monocytic IL-10 by tumor necrosis factor-alpha and cAMP elevating drugs
    • Platzer C, Meizel C, Vogt K, Platzer M, Volk HD. 1995. Up-regulation of monocytic IL-10 by tumor necrosis factor-alpha and cAMP elevating drugs. Int Immunol 7:517-523.
    • (1995) Int Immunol , vol.7 , pp. 517-523
    • Platzer, C.1    Meizel, C.2    Vogt, K.3    Platzer, M.4    Volk, H.D.5
  • 44
    • 0027940530 scopus 로고
    • Prostaglandins and inhibitors of arachidonate metabolism suppress experimental allergic encephalomyelitis
    • Reder AT, Thapar M, Sapugay AM, Jensen M. 1994. Prostaglandins and inhibitors of arachidonate metabolism suppress experimental allergic encephalomyelitis. J Neuroimmunol 54:117-127.
    • (1994) J Neuroimmunol , vol.54 , pp. 117-127
    • Reder, A.T.1    Thapar, M.2    Sapugay, A.M.3    Jensen, M.4
  • 45
    • 0028983573 scopus 로고
    • TNF-α expression by resident microglia and infiltrating leukocytes in the central nervous system of mice with experimental allergic encephalomyelitis
    • Renno T, Krakowski M, Piccirillo C, Jia-you L, Owens T. 1995. TNF-α expression by resident microglia and infiltrating leukocytes in the central nervous system of mice with experimental allergic encephalomyelitis. J Immunol 154:944-953.
    • (1995) J Immunol , vol.154 , pp. 944-953
    • Renno, T.1    Krakowski, M.2    Piccirillo, C.3    Jia-You, L.4    Owens, T.5
  • 46
    • 0028245010 scopus 로고
    • IL-10 prevents experimental allergic encephalomyelitis in rats
    • Rott O, Fleische B, Cash E. 1994. IL-10 prevents experimental allergic encephalomyelitis in rats. Eur J Immunol 24:1434-1440.
    • (1994) Eur J Immunol , vol.24 , pp. 1434-1440
    • Rott, O.1    Fleische, B.2    Cash, E.3
  • 47
    • 0029153012 scopus 로고
    • Tumor necrosis factor alpha upregulates microglial cell production of IL-10 in vitro
    • Sheng WS, Hu S, Kravitz FH, Peterson PK, Chao CC. 1995. Tumor necrosis factor alpha upregulates microglial cell production of IL-10 in vitro. Clin Diag Lab Immunol 2:604-608.
    • (1995) Clin Diag Lab Immunol , vol.2 , pp. 604-608
    • Sheng, W.S.1    Hu, S.2    Kravitz, F.H.3    Peterson, P.K.4    Chao, C.C.5
  • 49
    • 0024199439 scopus 로고
    • Functional plasticity of microglia: A review
    • Streit WJ, Graeber MB, Kreutzberg GW. 1988. Functional plasticity of microglia: a review. Glia 1:301-307.
    • (1988) Glia , vol.1 , pp. 301-307
    • Streit, W.J.1    Graeber, M.B.2    Kreutzberg, G.W.3
  • 50
    • 0031043631 scopus 로고    scopus 로고
    • Competitive PCR quantification of pro- and anti-inflammatory cytokine mRNA in the central nervous system during autoimmune encephalomyelitis
    • Tanuma N, Kojima T, Shin T, Aikawa Y, Kohji T, Ishihara Y, Matsumoto Y. 1997. Competitive PCR quantification of pro-and anti-inflammatory cytokine mRNA in the central nervous system during autoimmune encephalomyelitis. J Neuroimmunol 73:197-206.
    • (1997) J Neuroimmunol , vol.73 , pp. 197-206
    • Tanuma, N.1    Kojima, T.2    Shin, T.3    Aikawa, Y.4    Kohji, T.5    Ishihara, Y.6    Matsumoto, Y.7
  • 53
    • 0026969308 scopus 로고
    • Prostaglandins as modulators rather than mediators of inflammation
    • Weissmann G. 1993. Prostaglandins as modulators rather than mediators of inflammation. J Lipid Mediators 6:275-286.
    • (1993) J Lipid Mediators , vol.6 , pp. 275-286
    • Weissmann, G.1
  • 54
    • 0028960035 scopus 로고
    • Cytokines and murine autoimmune encephalomyelitis: Inhibition or enhancement of disease with antibodies to select cytokines, or by delivery of exogenous cytokines using a recombinant vaccinia virus system
    • Willenborg DO, Fordham SA, Cowden WB, Ramshaw IA. 1995. Cytokines and murine autoimmune encephalomyelitis: inhibition or enhancement of disease with antibodies to select cytokines, or by delivery of exogenous cytokines using a recombinant vaccinia virus system. Scand J Immunol 41:31-41.
    • (1995) Scand J Immunol , vol.41 , pp. 31-41
    • Willenborg, D.O.1    Fordham, S.A.2    Cowden, W.B.3    Ramshaw, I.A.4
  • 56
    • 0028988291 scopus 로고
    • 2, cholera toxin and 8-bromo-cyclic AMP on lipopolysaccharide-induced gene expression of cytokines in human macrophages
    • 2, cholera toxin and 8-bromo-cyclic AMP on lipopolysaccharide-induced gene expression of cytokines in human macrophages. Immunology 84:446-452.
    • (1995) Immunology , vol.84 , pp. 446-452
    • Zhong, W.W.1    Burke, P.A.2    Drotar, M.E.3    Chavali, S.R.4    Forse, R.A.5


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