Differential roles of PKA and Epac on the production of cytokines in the endotoxin-stimulated primary cultured microglia

Journal of Molecular Neuroscience

Volumn 45, Issue 2, 2011, Pages 186-193

  Liu, Jian ^a   Zhao, Xin ^a   Cao, Jianping ^b   Xue, Qingsheng ^a   Feng, Xiaomei ^a   Liu, Xuesheng ^a   Zhang, Fujun ^a   Yu, Buwei ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b PLA 455th Hospital   (China)

Author keywords

cAMP responsive guanine nucleotide exchange factor; Glycogen synthase kinase 3 ; Microglia; Mitogen activated protein kinases p38; Protein kinase A

Indexed keywords

8 (4 CHLOROPHENYLTHIO) 2 O METHYLADENOSINE 3,5 CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DERIVATIVE; CYCLIC AMP RESPONSIVE GUANINE NUCLEOTIDE EXCHANGE FACTOR; ENDOTOXIN; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; GLYCOGEN SYNTHASE KINASE 3BETA; GUANINE NUCLEOTIDE EXCHANGE FACTOR; INTERLEUKIN 10; INTERLEUKIN 1BETA; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; N6 BENZOYLADENOSINE 3,5 CYCLIC AMP; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE REPRESSION; GENETIC TRANSCRIPTION; MICROGLIA; NERVE CELL CULTURE; NONHUMAN; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; CELLS, CULTURED; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENDOTOXINS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; INTERLEUKIN-10; INTERLEUKIN-1BETA; MICROGLIA; RATS; RATS, SPRAGUE-DAWLEY; TUMOR NECROSIS FACTOR-ALPHA;

RATTUS;

EID: 80054902517     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-010-9426-x     Document Type: Article

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