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Volumn 2, Issue 2, 2007, Pages 222-231

Microglial activation is required for Aβ clearance after intracranial injection of lipopolysaccharide in APP transgenic mice

Author keywords

CD45; Complement receptor 3; Dexamethasone; Fc receptor; Macrosialin (CD68); Scavenger receptor class A

Indexed keywords

AMYLOID BETA PROTEIN; AUTACOID; LIPOPOLYSACCHARIDE;

EID: 34247502763     PISSN: 15571890     EISSN: 15571904     Source Type: Journal    
DOI: 10.1007/s11481-007-9069-z     Document Type: Article
Times cited : (122)

References (36)
  • 4
    • 0030038809 scopus 로고    scopus 로고
    • Scavenging of Alzheimer's amyloid beta-protein by microglia in culture
    • Ard MD, Cole GM, Wei J, Mehrle AP, Fratkin JD (1996) Scavenging of Alzheimer's amyloid beta-protein by microglia in culture. J Neurosci Res 43:190-202
    • (1996) J Neurosci Res , vol.43 , pp. 190-202
    • Ard, M.D.1    Cole, G.M.2    Wei, J.3    Mehrle, A.P.4    Fratkin, J.D.5
  • 5
    • 0035936009 scopus 로고    scopus 로고
    • Do nonsteroidal antiinflammatory drugs reduce the risk of Alzheimer's disease?
    • Breitner JC, Zandi PP (2001) Do nonsteroidal antiinflammatory drugs reduce the risk of Alzheimer's disease? N Engl J Med 345:1567-1568
    • (2001) N Engl J Med , vol.345 , pp. 1567-1568
    • Breitner, J.C.1    Zandi, P.P.2
  • 6
    • 0035696328 scopus 로고    scopus 로고
    • Intrahippocampal LPS injections reduce Abeta load in APP+PS1 transgenic mice
    • DiCarlo G, Wilcock D, Henderson D, Gordon M, Morgan D (2001) Intrahippocampal LPS injections reduce Abeta load in APP+PS1 transgenic mice. Neurobiol Aging 22:1007-1012
    • (2001) Neurobiol Aging , vol.22 , pp. 1007-1012
    • DiCarlo, G.1    Wilcock, D.2    Henderson, D.3    Gordon, M.4    Morgan, D.5
  • 8
    • 0030722556 scopus 로고    scopus 로고
    • Exaggerated astrocyte reactivity after nigrostriatal deafferentation in the aged rat
    • Gordon MN, Schreier WA, Ou X, Holcomb LA, Morgan DG (1997) Exaggerated astrocyte reactivity after nigrostriatal deafferentation in the aged rat, J Comp Neurol 388:106-119
    • (1997) J Comp Neurol , vol.388 , pp. 106-119
    • Gordon, M.N.1    Schreier, W.A.2    Ou, X.3    Holcomb, L.A.4    Morgan, D.G.5
  • 9
    • 33748253471 scopus 로고    scopus 로고
    • Glucocorticoids increase amyloid-beta and tau pathology in a mouse model of Alzheimer's disease
    • Green KN, Billings LM, Roozendaal B, McGaugh J, LaFerla FM (2006) Glucocorticoids increase amyloid-beta and tau pathology in a mouse model of Alzheimer's disease. J Neurosci 26:9047-9056
    • (2006) J Neurosci , vol.26 , pp. 9047-9056
    • Green, K.N.1    Billings, L.M.2    Roozendaal, B.3    McGaugh, J.4    LaFerla, F.M.5
  • 11
    • 5044222305 scopus 로고    scopus 로고
    • Time-dependent reduction in Aβ levels after intracranial LPS administration in APP transgenic mice
    • Herber DL, Roth LM, Wilson D, Wilson N, Mason JE, Morgan D, Gordon MN (2004) Time-dependent reduction in Aβ levels after intracranial LPS administration in APP transgenic mice. Exp Neurol 190:245-253
    • (2004) Exp Neurol , vol.190 , pp. 245-253
    • Herber, D.L.1    Roth, L.M.2    Wilson, D.3    Wilson, N.4    Mason, J.E.5    Morgan, D.6    Gordon, M.N.7
  • 12
    • 33644508018 scopus 로고    scopus 로고
    • Diverse microglial responses after intrahippocampal administration of lipopolysaccharide
    • Herber DL, Maloney JL, Roth LM, Freeman MJ, Morgan D, Gordon MN (2006) Diverse microglial responses after intrahippocampal administration of lipopolysaccharide. Glia 55:382-391
    • (2006) Glia , vol.55 , pp. 382-391
    • Herber, D.L.1    Maloney, J.L.2    Roth, L.M.3    Freeman, M.J.4    Morgan, D.5    Gordon, M.N.6
  • 14
    • 0036847848 scopus 로고    scopus 로고
    • Scavenger receptors in neurobiology and neuropathology: Their role on microglia and other cells of the nervous system
    • Husemann J, Loike JD, Anankov R, Febbraio M, Silverstein SC (2002) Scavenger receptors in neurobiology and neuropathology: their role on microglia and other cells of the nervous system. Glia 40:195-205
    • (2002) Glia , vol.40 , pp. 195-205
    • Husemann, J.1    Loike, J.D.2    Anankov, R.3    Febbraio, M.4    Silverstein, S.C.5
  • 15
    • 0037088914 scopus 로고    scopus 로고
    • Microglial activation and β-amyloid deposit reduction caused by a nitric oxide-releasing nonsteroidal anti-inflammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice
    • Jantzen PT, Connor KE, DiCarlo G, Wenk GL, Wallace JL, Rojiani AM, Coppola D, Morgan D, Gordon MN (2002) Microglial activation and β-amyloid deposit reduction caused by a nitric oxide-releasing nonsteroidal anti-inflammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice. J Neurosci 22:2246-2254
    • (2002) J Neurosci , vol.22 , pp. 2246-2254
    • Jantzen, P.T.1    Connor, K.E.2    DiCarlo, G.3    Wenk, G.L.4    Wallace, J.L.5    Rojiani, A.M.6    Coppola, D.7    Morgan, D.8    Gordon, M.N.9
  • 16
    • 0026717731 scopus 로고
    • Regulation of pinocytosis in murine macrophages by colony-stimulating factors and other agents
    • Knight KR, Vairo G, Hamilton JA (1992) Regulation of pinocytosis in murine macrophages by colony-stimulating factors and other agents. J Leukoc Biol 51:350-359
    • (1992) J Leukoc Biol , vol.51 , pp. 350-359
    • Knight, K.R.1    Vairo, G.2    Hamilton, J.A.3
  • 17
    • 7744235869 scopus 로고    scopus 로고
    • Microglial phagocytosis of fibrillar β-amyloid through a β1 integrin-dependent mechanism
    • Koenigsknecht J, Landreth G (2004) Microglial phagocytosis of fibrillar β-amyloid through a β1 integrin-dependent mechanism. J Neurosci 24:9838-9846
    • (2004) J Neurosci , vol.24 , pp. 9838-9846
    • Koenigsknecht, J.1    Landreth, G.2
  • 19
    • 11844255779 scopus 로고    scopus 로고
    • Bone-marrow-derived cells contribute to the recruitment of microglial cells in response to beta-amyloid deposition in APP/PS1 double transgenic Alzheimer mice
    • Malm TM, Koistinaho M, Parepalo M, Vatanen T, Ooka A, Karlsson S, Koistinaho J (2005) Bone-marrow-derived cells contribute to the recruitment of microglial cells in response to beta-amyloid deposition in APP/PS1 double transgenic Alzheimer mice. Neurobiol Dis 18:134-142
    • (2005) Neurobiol Dis , vol.18 , pp. 134-142
    • Malm, T.M.1    Koistinaho, M.2    Parepalo, M.3    Vatanen, T.4    Ooka, A.5    Karlsson, S.6    Koistinaho, J.7
  • 20
    • 34247507424 scopus 로고    scopus 로고
    • Mandrekar SD, Jiang Q, Reed-Geahan E, Landreth GA (2007) Microglia mediate the clearance of soluble amyloid beta through pinocytic mechanisms. Program number 270.8, Society for Neuroscience, 2006 Online
    • Mandrekar SD, Jiang Q, Reed-Geahan E, Landreth GA (2007) Microglia mediate the clearance of soluble amyloid beta through pinocytic mechanisms. Program number 270.8, Society for Neuroscience, 2006 Online
  • 21
    • 24644438615 scopus 로고    scopus 로고
    • Dynamic complexity of the microglial activation response in transgenic models of amyloid deposition: Implications for Alzheimer therapeutics
    • Morgan D, Gordon MN, Tan J, Wilcock D, Rojiani A (2005) Dynamic complexity of the microglial activation response in transgenic models of amyloid deposition: implications for Alzheimer therapeutics. J Neuropathol Exp Neurol 64:743-753
    • (2005) J Neuropathol Exp Neurol , vol.64 , pp. 743-753
    • Morgan, D.1    Gordon, M.N.2    Tan, J.3    Wilcock, D.4    Rojiani, A.5
  • 22
    • 0038722154 scopus 로고    scopus 로고
    • Glucocorticoids play a fundamental role in protecting the brain during innate immune response
    • Nadeau S, Rivest S (2003) Glucocorticoids play a fundamental role in protecting the brain during innate immune response. J Neurosci 23:5536-5544
    • (2003) J Neurosci , vol.23 , pp. 5536-5544
    • Nadeau, S.1    Rivest, S.2
  • 23
    • 4744370253 scopus 로고    scopus 로고
    • Signal transduction by the lipopolysaccharide receptor, Toll-like receptor-4
    • Palsson-McDermott EM, O'Neill LA (2004) Signal transduction by the lipopolysaccharide receptor, Toll-like receptor-4, Immunology 113:153-162
    • (2004) Immunology , vol.113 , pp. 153-162
    • Palsson-McDermott, E.M.1    O'Neill, L.A.2
  • 24
    • 0035794989 scopus 로고    scopus 로고
    • Dexamethasone inhibits the antigen presentation of dendritic cells in MHC class II pathway
    • Pan J, Ju D, Wang Q, Zhang M, Xia D, Zhang L, Yu H, Cao X (2001) Dexamethasone inhibits the antigen presentation of dendritic cells in MHC class II pathway. J Immunol Lett 76:153-161
    • (2001) J Immunol Lett , vol.76 , pp. 153-161
    • Pan, J.1    Ju, D.2    Wang, Q.3    Zhang, M.4    Xia, D.5    Zhang, L.6    Yu, H.7    Cao, X.8
  • 25
    • 0035726544 scopus 로고    scopus 로고
    • Neuroinflammation-induced acceleration of amyloid deposition in the APPV717F transgenic mouse
    • Qiao X, Cummins DJ, Paul SM (2001) Neuroinflammation-induced acceleration of amyloid deposition in the APPV717F transgenic mouse. Eur J Neurosci 14:474-482
    • (2001) Eur J Neurosci , vol.14 , pp. 474-482
    • Qiao, X.1    Cummins, D.J.2    Paul, S.M.3
  • 26
    • 0037376760 scopus 로고    scopus 로고
    • Inflammation and cerebral amyloidosis are disconnected in an animal model of Alzheimer's disease
    • Quinn J, Montine T, Morrow J, Woodward WR, Kulhanek D, Eckenstein F (2003) Inflammation and cerebral amyloidosis are disconnected in an animal model of Alzheimer's disease. J Neuroimmunol 137:32-41
    • (2003) J Neuroimmunol , vol.137 , pp. 32-41
    • Quinn, J.1    Montine, T.2    Morrow, J.3    Woodward, W.R.4    Kulhanek, D.5    Eckenstein, F.6
  • 29
    • 0042835437 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced-neuroinflammation increases intracellular accumulation of amyloid precursor protein and amyloid beta peptide in APPswe transgenic mice
    • Sheng JG, Bora SH, Xu G, Borchelt DR, Price DL, Koliatsos VE (2003) Lipopolysaccharide-induced-neuroinflammation increases intracellular accumulation of amyloid precursor protein and amyloid beta peptide in APPswe transgenic mice. Neurobiol Dis 14:133-145
    • (2003) Neurobiol Dis , vol.14 , pp. 133-145
    • Sheng, J.G.1    Bora, S.H.2    Xu, G.3    Borchelt, D.R.4    Price, D.L.5    Koliatsos, V.E.6
  • 30
    • 0035704245 scopus 로고    scopus 로고
    • Endogenous brain cytokine mRNA and inflammatory responses to lipopolysaccharide are elevated in the Tg2576 transgenic mouse model of Alzheimer's disease
    • Sly LM, Krzesicki RF, Brashler JR, Buhl AE, McKinley DD, Carter DB, Chin JE (2001) Endogenous brain cytokine mRNA and inflammatory responses to lipopolysaccharide are elevated in the Tg2576 transgenic mouse model of Alzheimer's disease. Brain Res Bull 56:581-588
    • (2001) Brain Res Bull , vol.56 , pp. 581-588
    • Sly, L.M.1    Krzesicki, R.F.2    Brashler, J.R.3    Buhl, A.E.4    McKinley, D.D.5    Carter, D.B.6    Chin, J.E.7
  • 31
    • 0038291979 scopus 로고    scopus 로고
    • IL-10 and glucocorticoids inhibit Abeta(1-42)- and lipopolysaccharide-induced pro-inflammatory cytokine and chemokine induction in the central nervous system
    • Szczepanik AM, Ringheim GE (2003) IL-10 and glucocorticoids inhibit Abeta(1-42)- and lipopolysaccharide-induced pro-inflammatory cytokine and chemokine induction in the central nervous system, J Alzheimers Dis 5:105-117
    • (2003) J Alzheimers Dis , vol.5 , pp. 105-117
    • Szczepanik, A.M.1    Ringheim, G.E.2
  • 32
    • 0031149325 scopus 로고    scopus 로고
    • Glucocorticoid- and mineralocorticoid receptors in microglial cells: The two receptors mediate differential effects of corticosteroids
    • Tanaka J, Fujita H, Matsuda S, Toku K, Sakanaka M, Maeda N (1997) Glucocorticoid- and mineralocorticoid receptors in microglial cells: the two receptors mediate differential effects of corticosteroids. Glia 20:23-27
    • (1997) Glia , vol.20 , pp. 23-27
    • Tanaka, J.1    Fujita, H.2    Matsuda, S.3    Toku, K.4    Sakanaka, M.5    Maeda, N.6
  • 34
    • 0037531198 scopus 로고    scopus 로고
    • Intracranially administered anti-Aβ antibodies reduce β-amyloid deposition by mechanisms independent of and associated with microglial activation
    • Wilcock DM, DiCarlo G, Henderson D, Jackson J, Clarke K, Ugen KE, Gordon MN, Morgan D (2003) Intracranially administered anti-Aβ antibodies reduce β-amyloid deposition by mechanisms independent of and associated with microglial activation. J Neurosci 213:3745-3751
    • (2003) J Neurosci , vol.213 , pp. 3745-3751
    • Wilcock, D.M.1    DiCarlo, G.2    Henderson, D.3    Jackson, J.4    Clarke, K.5    Ugen, K.E.6    Gordon, M.N.7    Morgan, D.8
  • 35
    • 1642497601 scopus 로고    scopus 로고
    • Microglial activation facilitates Abeta plaque removal following intracranial anti-Abeta antibody administration
    • Wilcock DM, Munireddy SK, Rosenthal A, Ugen KE, Gordon MN, Morgan D (2004) Microglial activation facilitates Abeta plaque removal following intracranial anti-Abeta antibody administration. Neurobiol Dis 15:11-20
    • (2004) Neurobiol Dis , vol.15 , pp. 11-20
    • Wilcock, D.M.1    Munireddy, S.K.2    Rosenthal, A.3    Ugen, K.E.4    Gordon, M.N.5    Morgan, D.6
  • 36
    • 0032957398 scopus 로고    scopus 로고
    • Dexamethasone selectively suppresses microglial trophic responses to hippocampal deafferentation
    • Woods AG, Poulsen FR, Gall CM (1999) Dexamethasone selectively suppresses microglial trophic responses to hippocampal deafferentation. Neuroscience 91:1277-1289
    • (1999) Neuroscience , vol.91 , pp. 1277-1289
    • Woods, A.G.1    Poulsen, F.R.2    Gall, C.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.