Mycoepoxydiene inhibits activation of BV2 microglia stimulated by lipopolysaccharide through suppressing NF-κB, ERK 1/2 and toll-like receptor pathways

International Immunopharmacology

Volumn 19, Issue 1, 2014, Pages 88-93

  Su, Xinhui ^a   Chen, Qiang ^b   Chen, Wenbo ^b   Chen, Tenghui ^b   Li, Wenjiao ^b   Li, Yang ^b   Dou, Xiaofeng ^a   Zhang, Yafei ^a   Shen, Yuemao ^c   Wu, Hua ^a   Yu, Chundong ^b  

^a THE FIRST AFFILIATED HOSPITAL OF XIAMEN UNIVERSITY   (China)

^b XIAMEN UNIVERSITY   (China)

^c SHANDONG UNIVERSITY   (China)

Author keywords

Microglia; Mitogen activated protein kinase; Mycoepoxydiene; NF B; Pro inflammatory mediators; Toll like receptor

Indexed keywords

GAMMA INTERFERON; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MYCOEPOXYDIENE; NITRIC OXIDE; POLYKETIDE; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 4; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CYTOTOXICITY; DEGENERATIVE DISEASE; DEGRADATION; MEDIATOR; MICROGLIA; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL;

MICROGLIA; MITOGEN-ACTIVATED PROTEIN KINASE; MYCOEPOXYDIENE; NF-ΚB; PRO-INFLAMMATORY MEDIATORS; TOLL-LIKE RECEPTOR;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BRIDGED COMPOUNDS; CELL LINE; CELL SURVIVAL; CYTOKINES; LIPOPOLYSACCHARIDES; MICE; MICROGLIA; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NF-KAPPA B; NITRIC OXIDE; PYRONES; TOLL-LIKE RECEPTOR 4;

EID: 84893323756     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2014.01.004     Document Type: Article

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