메뉴 건너뛰기




Volumn 28, Issue 6, 2007, Pages 894-906

Interleukin-10 protects against inflammation-mediated degeneration of dopaminergic neurons in substantia nigra

Author keywords

Apoptosis; Dopaminergic neuron; Inflammation; Interleukin 10 (IL 10); Lipopolysaccharide (LPS); Microglia; Neurodegeneration; Parkinson's disease (PD)

Indexed keywords

CASPASE 3; CYTOKINE; FAS ANTIGEN; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2; RECOMBINANT INTERLEUKIN 10; RIBONUCLEASE; TUMOR NECROSIS FACTOR ALPHA;

EID: 34247157292     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2006.04.011     Document Type: Article
Times cited : (120)

References (83)
  • 2
    • 0037330339 scopus 로고    scopus 로고
    • Up-regulation of inducible nitric oxide synthase in the substantia nigra by lipopolysaccharide causes microglial activation and neurodegeneration
    • Arimoto T., and Bing G. Up-regulation of inducible nitric oxide synthase in the substantia nigra by lipopolysaccharide causes microglial activation and neurodegeneration. Neurobiol Dis 12 1 (2003) 35-45
    • (2003) Neurobiol Dis , vol.12 , Issue.1 , pp. 35-45
    • Arimoto, T.1    Bing, G.2
  • 3
    • 0035341472 scopus 로고    scopus 로고
    • Interleukin-10 prevents glutamate-mediated cerebellar granule cell death by blocking caspase-3-like activity
    • Bachis A., Colangelo A.M., Vicini S., Doe P.P., De Bernardi M.A., Brooker G., et al. Interleukin-10 prevents glutamate-mediated cerebellar granule cell death by blocking caspase-3-like activity. J Neurosci 21 9 (2001) 3104-3112
    • (2001) J Neurosci , vol.21 , Issue.9 , pp. 3104-3112
    • Bachis, A.1    Colangelo, A.M.2    Vicini, S.3    Doe, P.P.4    De Bernardi, M.A.5    Brooker, G.6
  • 4
    • 0029592005 scopus 로고
    • Activation of the inducible form of nitric oxide synthase in the brains of patients with multiple sclerosis
    • Bagasra O., Michaels F.H., Zheng Y.M., Bobroski L.E., Spitsin S.V., Fu Z.F., et al. Activation of the inducible form of nitric oxide synthase in the brains of patients with multiple sclerosis. Proc Natl Acad Sci USA 92 26 (1995) 12041-12045
    • (1995) Proc Natl Acad Sci USA , vol.92 , Issue.26 , pp. 12041-12045
    • Bagasra, O.1    Michaels, F.H.2    Zheng, Y.M.3    Bobroski, L.E.4    Spitsin, S.V.5    Fu, Z.F.6
  • 5
    • 0029874138 scopus 로고    scopus 로고
    • The NF-kappa B and I kappa B proteins: new discoveries and insights
    • Baldwin Jr. A.S. The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu Rev Immunol 14 (1996) 649-683
    • (1996) Annu Rev Immunol , vol.14 , pp. 649-683
    • Baldwin Jr., A.S.1
  • 6
    • 0029781523 scopus 로고    scopus 로고
    • Regulation of CD14 expression on human adult central nervous system-derived microglia
    • Becher B., Fedorowicz V., and Antel J.P. Regulation of CD14 expression on human adult central nervous system-derived microglia. J Neurosci Res 45 4 (1996) 375-381
    • (1996) J Neurosci Res , vol.45 , Issue.4 , pp. 375-381
    • Becher, B.1    Fedorowicz, V.2    Antel, J.P.3
  • 7
    • 26044452149 scopus 로고    scopus 로고
    • Microglia mediated dopaminergic cell death in the substantia nigra: a new animal model for Parkinson's disease
    • Bing G., Lu X., Zheng N., Jin L., Qi Y., and Kim H.-C. Microglia mediated dopaminergic cell death in the substantia nigra: a new animal model for Parkinson's disease. Neurosci Abstr 24 (1998) 44
    • (1998) Neurosci Abstr , vol.24 , pp. 44
    • Bing, G.1    Lu, X.2    Zheng, N.3    Jin, L.4    Qi, Y.5    Kim, H.-C.6
  • 8
    • 0028364696 scopus 로고
    • Immunocytochemical analysis of tumor necrosis factor and its receptors in Parkinson's disease
    • Boka G., Anglade P., Wallach D., Javoy-Agid F., Agid Y., and Hirsch E.C. Immunocytochemical analysis of tumor necrosis factor and its receptors in Parkinson's disease. Neurosci Lett 172 1-2 (1994) 151-154
    • (1994) Neurosci Lett , vol.172 , Issue.1-2 , pp. 151-154
    • Boka, G.1    Anglade, P.2    Wallach, D.3    Javoy-Agid, F.4    Agid, Y.5    Hirsch, E.C.6
  • 9
    • 0028867452 scopus 로고
    • Glia-dependent neurotoxicity and neuroprotection in mesencephalic cultures
    • Bronstein D.M., Perez-Otano I., Sun V., Mullis Sawin S.B., Chan J., Wu G.C., et al. Glia-dependent neurotoxicity and neuroprotection in mesencephalic cultures. Brain Res 704 1 (1995) 112-126
    • (1995) Brain Res , vol.704 , Issue.1 , pp. 112-126
    • Bronstein, D.M.1    Perez-Otano, I.2    Sun, V.3    Mullis Sawin, S.B.4    Chan, J.5    Wu, G.C.6
  • 11
    • 0031881687 scopus 로고    scopus 로고
    • Lipopolysaccharide intranigral injection induces inflammatory reaction and damage in nigrostriatal dopaminergic system
    • Castano A., Herrera A.J., Cano J., and Machado A. Lipopolysaccharide intranigral injection induces inflammatory reaction and damage in nigrostriatal dopaminergic system. J Neurochem 70 4 (1998) 1584-1592
    • (1998) J Neurochem , vol.70 , Issue.4 , pp. 1584-1592
    • Castano, A.1    Herrera, A.J.2    Cano, J.3    Machado, A.4
  • 12
    • 0026738695 scopus 로고
    • Activated microglia mediate neuronal cell injury via a nitric oxide mechanism
    • Chao C.C., Hu S., Molitor T.W., Shaskan E.G., and Peterson P.K. Activated microglia mediate neuronal cell injury via a nitric oxide mechanism. J Immunol 149 8 (1992) 2736-2741
    • (1992) J Immunol , vol.149 , Issue.8 , pp. 2736-2741
    • Chao, C.C.1    Hu, S.2    Molitor, T.W.3    Shaskan, E.G.4    Peterson, P.K.5
  • 13
    • 0029078126 scopus 로고
    • Tumor necrosis factor-alpha production by human fetal microglial cells: regulation by other cytokines
    • Chao C.C., Hu S., Sheng W.S., and Peterson P.K. Tumor necrosis factor-alpha production by human fetal microglial cells: regulation by other cytokines. Dev Neurosci 17 2 (1995) 97-105
    • (1995) Dev Neurosci , vol.17 , Issue.2 , pp. 97-105
    • Chao, C.C.1    Hu, S.2    Sheng, W.S.3    Peterson, P.K.4
  • 14
    • 0037383434 scopus 로고    scopus 로고
    • CXCL10 production from cytomegalovirus-stimulated microglia is regulated by both human and viral interleukin-10
    • Cheeran M.C., Hu S., Sheng W.S., Peterson P.K., and Lokensgard J.R. CXCL10 production from cytomegalovirus-stimulated microglia is regulated by both human and viral interleukin-10. J Virol 77 8 (2003) 4502-4515
    • (2003) J Virol , vol.77 , Issue.8 , pp. 4502-4515
    • Cheeran, M.C.1    Hu, S.2    Sheng, W.S.3    Peterson, P.K.4    Lokensgard, J.R.5
  • 15
    • 0035116226 scopus 로고    scopus 로고
    • Dopaminergic cell death induced by MPP(+), oxidant and specific neurotoxicants shares the common molecular mechanism
    • Chun H.S., Gibson G.E., DeGiorgio L.A., Zhang H., Kidd V.J., and Son J.H. Dopaminergic cell death induced by MPP(+), oxidant and specific neurotoxicants shares the common molecular mechanism. J Neurochem 76 4 (2001) 1010-1021
    • (2001) J Neurochem , vol.76 , Issue.4 , pp. 1010-1021
    • Chun, H.S.1    Gibson, G.E.2    DeGiorgio, L.A.3    Zhang, H.4    Kidd, V.J.5    Son, J.H.6
  • 16
    • 0027354484 scopus 로고
    • Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease
    • Dickson D.W., Lee S.C., Mattiace L.A., Yen S.H., and Brosnan C. Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease. Glia 7 1 (1993) 75-83
    • (1993) Glia , vol.7 , Issue.1 , pp. 75-83
    • Dickson, D.W.1    Lee, S.C.2    Mattiace, L.A.3    Yen, S.H.4    Brosnan, C.5
  • 17
    • 0032837804 scopus 로고    scopus 로고
    • Postischemic hypothermia and IL-10 treatment provide long-lasting neuroprotection of CA1 hippocampus following transient global ischemia in rats
    • Dietrich W.D., Busto R., and Bethea J.R. Postischemic hypothermia and IL-10 treatment provide long-lasting neuroprotection of CA1 hippocampus following transient global ischemia in rats. Exp Neurol 158 2 (1999) 444-450
    • (1999) Exp Neurol , vol.158 , Issue.2 , pp. 444-450
    • Dietrich, W.D.1    Busto, R.2    Bethea, J.R.3
  • 18
    • 0030945446 scopus 로고    scopus 로고
    • Inducible nitric-oxide synthase and nitric oxide production in human fetal astrocytes and microglia. A kinetic analysis
    • Ding M., St Pierre B.A., Parkinson J.F., Medberry P., Wong J.L., Rogers N.E., et al. Inducible nitric-oxide synthase and nitric oxide production in human fetal astrocytes and microglia. A kinetic analysis. J Biol Chem 272 17 (1997) 11327-11335
    • (1997) J Biol Chem , vol.272 , Issue.17 , pp. 11327-11335
    • Ding, M.1    St Pierre, B.A.2    Parkinson, J.F.3    Medberry, P.4    Wong, J.L.5    Rogers, N.E.6
  • 20
    • 0028124916 scopus 로고
    • Nitric oxide synthase activity is elevated in brain microvessels in Alzheimer's disease
    • Dorheim M.A., Tracey W.R., Pollock J.S., and Grammas P. Nitric oxide synthase activity is elevated in brain microvessels in Alzheimer's disease. Biochem Biophys Res Commun 205 1 (1994) 659-665
    • (1994) Biochem Biophys Res Commun , vol.205 , Issue.1 , pp. 659-665
    • Dorheim, M.A.1    Tracey, W.R.2    Pollock, J.S.3    Grammas, P.4
  • 21
    • 0032169015 scopus 로고    scopus 로고
    • Regulation by endogenous interleukin-10 of the expression of nitric oxide synthase induced after ligation of CD23 in human macrophages
    • Dugas N., Palacios-Calender M., Dugas B., Riveros-Moreno V., Delfraissy J.F., Kolb J.P., et al. Regulation by endogenous interleukin-10 of the expression of nitric oxide synthase induced after ligation of CD23 in human macrophages. Cytokine 10 9 (1998) 680-689
    • (1998) Cytokine , vol.10 , Issue.9 , pp. 680-689
    • Dugas, N.1    Palacios-Calender, M.2    Dugas, B.3    Riveros-Moreno, V.4    Delfraissy, J.F.5    Kolb, J.P.6
  • 22
    • 0029978182 scopus 로고    scopus 로고
    • Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis
    • Enari M., Talanian R.V., Wong W.W., and Nagata S. Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis. Nature 380 6576 (1996) 723-726
    • (1996) Nature , vol.380 , Issue.6576 , pp. 723-726
    • Enari, M.1    Talanian, R.V.2    Wong, W.W.3    Nagata, S.4
  • 24
    • 0033608739 scopus 로고    scopus 로고
    • Increased nitrotyrosine immunoreactivity in substantia nigra neurons in MPTP treated baboons is blocked by inhibition of neuronal nitric oxide synthase
    • Ferrante R.J., Hantraye P., Brouillet E., and Beal M.F. Increased nitrotyrosine immunoreactivity in substantia nigra neurons in MPTP treated baboons is blocked by inhibition of neuronal nitric oxide synthase. Brain Res 823 1-2 (1999) 177-182
    • (1999) Brain Res , vol.823 , Issue.1-2 , pp. 177-182
    • Ferrante, R.J.1    Hantraye, P.2    Brouillet, E.3    Beal, M.F.4
  • 25
    • 0037189042 scopus 로고    scopus 로고
    • Interleukin-10 reverses acute detrimental effects of endotoxin-induced inflammation on perinatal cerebral hypoxia-ischemia
    • Froen J.F., Munkeby B.H., Stray-Pedersen B., and Saugstad O.D. Interleukin-10 reverses acute detrimental effects of endotoxin-induced inflammation on perinatal cerebral hypoxia-ischemia. Brain Res 942 1-2 (2002) 87-94
    • (2002) Brain Res , vol.942 , Issue.1-2 , pp. 87-94
    • Froen, J.F.1    Munkeby, B.H.2    Stray-Pedersen, B.3    Saugstad, O.D.4
  • 26
    • 0029664477 scopus 로고    scopus 로고
    • CD14 mediate endotoxin induction of nitric oxide synthase in cultured brain glial cells
    • Galea E., Reis D.J., Fox E.S., Xu H., and Feinstein D.L. CD14 mediate endotoxin induction of nitric oxide synthase in cultured brain glial cells. J Neuroimmunol 64 1 (1996) 19-28
    • (1996) J Neuroimmunol , vol.64 , Issue.1 , pp. 19-28
    • Galea, E.1    Reis, D.J.2    Fox, E.S.3    Xu, H.4    Feinstein, D.L.5
  • 27
    • 0032943113 scopus 로고    scopus 로고
    • Chemokines and chemokine receptors in CNS pathology
    • Glabinski A.R., and Ransohoff R.M. Chemokines and chemokine receptors in CNS pathology. J Neurovirol 5 1 (1999) 3-12
    • (1999) J Neurovirol , vol.5 , Issue.1 , pp. 3-12
    • Glabinski, A.R.1    Ransohoff, R.M.2
  • 28
    • 0033378329 scopus 로고    scopus 로고
    • Sentries at the gate: chemokines and the blood-brain barrier
    • Glabinski A.R., and Ransohoff R.M. Sentries at the gate: chemokines and the blood-brain barrier. J Neurovirol 5 6 (1999) 623-634
    • (1999) J Neurovirol , vol.5 , Issue.6 , pp. 623-634
    • Glabinski, A.R.1    Ransohoff, R.M.2
  • 29
    • 0033930743 scopus 로고    scopus 로고
    • Interleukin-10 modulates neuronal threshold of vulnerability to ischaemic damage
    • Grilli M., Barbieri I., Basudev H., Brusa R., Casati C., Lozza G., et al. Interleukin-10 modulates neuronal threshold of vulnerability to ischaemic damage. Eur J Neurosci 12 7 (2000) 2265-2272
    • (2000) Eur J Neurosci , vol.12 , Issue.7 , pp. 2265-2272
    • Grilli, M.1    Barbieri, I.2    Basudev, H.3    Brusa, R.4    Casati, C.5    Lozza, G.6
  • 30
    • 0032875348 scopus 로고    scopus 로고
    • Vascular effects of lipopolysaccharide are enhanced in interleukin-10-deficient mice
    • [discussion 5-6]
    • Gunnett C.A., Berg D.J., Faraci F.M., and Feuerstein G. Vascular effects of lipopolysaccharide are enhanced in interleukin-10-deficient mice. Stroke 30 10 (1999) 2191-2195 [discussion 5-6]
    • (1999) Stroke , vol.30 , Issue.10 , pp. 2191-2195
    • Gunnett, C.A.1    Berg, D.J.2    Faraci, F.M.3    Feuerstein, G.4
  • 31
    • 0027276870 scopus 로고
    • Ciliary neurotrophic factor prevents degeneration of adult rat substantia nigra dopaminergic neurons in vivo
    • Hagg T., and Varon S. Ciliary neurotrophic factor prevents degeneration of adult rat substantia nigra dopaminergic neurons in vivo. Proc Natl Acad Sci USA 90 13 (1993) 6315-6319
    • (1993) Proc Natl Acad Sci USA , vol.90 , Issue.13 , pp. 6315-6319
    • Hagg, T.1    Varon, S.2
  • 32
    • 84975751684 scopus 로고
    • Complex I inhibitors induce dose-dependent apoptosis in PC12 cells: relevance to Parkinson's disease
    • Hartley A., Stone J.M., Heron C., Cooper J.M., and Schapira A.H. Complex I inhibitors induce dose-dependent apoptosis in PC12 cells: relevance to Parkinson's disease. J Neurochem 63 5 (1994) 1987-1990
    • (1994) J Neurochem , vol.63 , Issue.5 , pp. 1987-1990
    • Hartley, A.1    Stone, J.M.2    Heron, C.3    Cooper, J.M.4    Schapira, A.H.5
  • 33
    • 0037154136 scopus 로고    scopus 로고
    • FADD: a link between TNF family receptors and caspases in Parkinson's disease
    • Hartmann A., Mouatt-Prigent A., Faucheux B.A., Agid Y., and Hirsch E.C. FADD: a link between TNF family receptors and caspases in Parkinson's disease. Neurology 58 2 (2002) 308-310
    • (2002) Neurology , vol.58 , Issue.2 , pp. 308-310
    • Hartmann, A.1    Mouatt-Prigent, A.2    Faucheux, B.A.3    Agid, Y.4    Hirsch, E.C.5
  • 34
    • 0035800589 scopus 로고    scopus 로고
    • Minocycline inhibits microglial activation and protects nigral cells after 6-hydroxydopamine injection into mouse striatum
    • He Y., Appel S., and Le W. Minocycline inhibits microglial activation and protects nigral cells after 6-hydroxydopamine injection into mouse striatum. Brain Res 909 1-2 (2001) 187-193
    • (2001) Brain Res , vol.909 , Issue.1-2 , pp. 187-193
    • He, Y.1    Appel, S.2    Le, W.3
  • 35
    • 0033835748 scopus 로고    scopus 로고
    • The single intranigral injection of LPS as a new model for studying the selective effects of inflammatory reactions on dopaminergic system
    • Herrera A.J., Castano A., Venero J.L., Cano J., and Machado A. The single intranigral injection of LPS as a new model for studying the selective effects of inflammatory reactions on dopaminergic system. Neurobiol Dis 7 4 (2000) 429-447
    • (2000) Neurobiol Dis , vol.7 , Issue.4 , pp. 429-447
    • Herrera, A.J.1    Castano, A.2    Venero, J.L.3    Cano, J.4    Machado, A.5
  • 37
    • 0029140838 scopus 로고
    • Cytokine modulation of murine microglial cell superoxide production
    • Hu S., Sheng W.S., Peterson P.K., and Chao C.C. Cytokine modulation of murine microglial cell superoxide production. Glia 13 1 (1995) 45-50
    • (1995) Glia , vol.13 , Issue.1 , pp. 45-50
    • Hu, S.1    Sheng, W.S.2    Peterson, P.K.3    Chao, C.C.4
  • 39
    • 0032146801 scopus 로고    scopus 로고
    • Induction of human immunodeficiency virus type 1 replication in human glial cells after proinflammatory cytokines stimulation: effect of IFNgamma, IL1beta, and TNFalpha on differentiation and chemokine production in glial cells
    • Janabi N., Di Stefano M., Wallon C., Hery C., Chiodi F., and Tardieu M. Induction of human immunodeficiency virus type 1 replication in human glial cells after proinflammatory cytokines stimulation: effect of IFNgamma, IL1beta, and TNFalpha on differentiation and chemokine production in glial cells. Glia 23 4 (1998) 304-315
    • (1998) Glia , vol.23 , Issue.4 , pp. 304-315
    • Janabi, N.1    Di Stefano, M.2    Wallon, C.3    Hery, C.4    Chiodi, F.5    Tardieu, M.6
  • 40
    • 0034663061 scopus 로고    scopus 로고
    • Regional difference in susceptibility to lipopolysaccharide-induced neurotoxicity in the rat brain: role of microglia
    • Kim W.G., Mohney R.P., Wilson B., Jeohn G.H., Liu B., and Hong J.S. Regional difference in susceptibility to lipopolysaccharide-induced neurotoxicity in the rat brain: role of microglia. J Neurosci 20 16 (2000) 6309-6316
    • (2000) J Neurosci , vol.20 , Issue.16 , pp. 6309-6316
    • Kim, W.G.1    Mohney, R.P.2    Wilson, B.3    Jeohn, G.H.4    Liu, B.5    Hong, J.S.6
  • 41
    • 0031738971 scopus 로고    scopus 로고
    • DNA fragmentation in human substantia nigra: apoptosis or perimortem effect?
    • Kingsbury A.E., Mardsen C.D., and Foster O.J. DNA fragmentation in human substantia nigra: apoptosis or perimortem effect?. Mov Disord 13 6 (1998) 877-884
    • (1998) Mov Disord , vol.13 , Issue.6 , pp. 877-884
    • Kingsbury, A.E.1    Mardsen, C.D.2    Foster, O.J.3
  • 42
    • 0031713714 scopus 로고    scopus 로고
    • Interleukin-10 improves outcome and alters proinflammatory cytokine expression after experimental traumatic brain injury
    • Knoblach S.M., and Faden A.I. Interleukin-10 improves outcome and alters proinflammatory cytokine expression after experimental traumatic brain injury. Exp Neurol 153 1 (1998) 143-151
    • (1998) Exp Neurol , vol.153 , Issue.1 , pp. 143-151
    • Knoblach, S.M.1    Faden, A.I.2
  • 43
    • 17044373214 scopus 로고    scopus 로고
    • Interleukin-10 inhibits endotoxin-induced pro-inflammatory cytokines in microglial cell cultures
    • Kremlev S.G., and Palmer C. Interleukin-10 inhibits endotoxin-induced pro-inflammatory cytokines in microglial cell cultures. J Neuroimmunol 162 1-2 (2005) 71-80
    • (2005) J Neuroimmunol , vol.162 , Issue.1-2 , pp. 71-80
    • Kremlev, S.G.1    Palmer, C.2
  • 44
    • 1542396688 scopus 로고    scopus 로고
    • Differential expression of chemokines and chemokine receptors during microglial activation and inhibition
    • Kremlev S.G., Roberts R.L., and Palmer C. Differential expression of chemokines and chemokine receptors during microglial activation and inhibition. J Neuroimmunol 149 1-2 (2004) 1-9
    • (2004) J Neuroimmunol , vol.149 , Issue.1-2 , pp. 1-9
    • Kremlev, S.G.1    Roberts, R.L.2    Palmer, C.3
  • 45
    • 0025220976 scopus 로고
    • Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain
    • Lawson L.J., Perry V.H., Dri P., and Gordon S. Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain. Neuroscience 39 1 (1990) 151-170
    • (1990) Neuroscience , vol.39 , Issue.1 , pp. 151-170
    • Lawson, L.J.1    Perry, V.H.2    Dri, P.3    Gordon, S.4
  • 46
    • 0034032594 scopus 로고    scopus 로고
    • Interleukin-10, interleukin-4, and transforming growth factor-beta differentially regulate lipopolysaccharide-induced production of pro-inflammatory cytokines and nitric oxide in co-cultures of rat astroglial and microglial cells
    • Ledeboer A., Breve J.J., Poole S., Tilders F.J., and Van Dam A.M. Interleukin-10, interleukin-4, and transforming growth factor-beta differentially regulate lipopolysaccharide-induced production of pro-inflammatory cytokines and nitric oxide in co-cultures of rat astroglial and microglial cells. Glia 30 2 (2000) 134-142
    • (2000) Glia , vol.30 , Issue.2 , pp. 134-142
    • Ledeboer, A.1    Breve, J.J.2    Poole, S.3    Tilders, F.J.4    Van Dam, A.M.5
  • 48
    • 0027298505 scopus 로고
    • Cytokine production by human fetal microglia and astrocytes. Differential induction by lipopolysaccharide and IL-1 beta
    • Lee S.C., Liu W., Dickson D.W., Brosnan C.F., and Berman J.W. Cytokine production by human fetal microglia and astrocytes. Differential induction by lipopolysaccharide and IL-1 beta. J Immunol 150 7 (1993) 2659-2667
    • (1993) J Immunol , vol.150 , Issue.7 , pp. 2659-2667
    • Lee, S.C.1    Liu, W.2    Dickson, D.W.3    Brosnan, C.F.4    Berman, J.W.5
  • 49
    • 0027450149 scopus 로고
    • The possible contribution of microglia and macrophages to delayed neuronal death after ischemia
    • Lees G.J. The possible contribution of microglia and macrophages to delayed neuronal death after ischemia. J Neurol Sci 114 2 (1993) 119-122
    • (1993) J Neurol Sci , vol.114 , Issue.2 , pp. 119-122
    • Lees, G.J.1
  • 50
    • 0034015558 scopus 로고    scopus 로고
    • Naloxone protects rat dopaminergic neurons against inflammatory damage through inhibition of microglia activation and superoxide generation
    • Liu B., Du L., and Hong J.S. Naloxone protects rat dopaminergic neurons against inflammatory damage through inhibition of microglia activation and superoxide generation. J Pharmacol Exp Ther 293 2 (2000) 607-617
    • (2000) J Pharmacol Exp Ther , vol.293 , Issue.2 , pp. 607-617
    • Liu, B.1    Du, L.2    Hong, J.S.3
  • 51
    • 0029956457 scopus 로고    scopus 로고
    • Regulation of microglial activation by TGF-beta, IL-10, and CSF-1
    • Lodge P.A., and Sriram S. Regulation of microglial activation by TGF-beta, IL-10, and CSF-1. J Leukoc Biol 60 4 (1996) 502-508
    • (1996) J Leukoc Biol , vol.60 , Issue.4 , pp. 502-508
    • Lodge, P.A.1    Sriram, S.2
  • 52
    • 0034008991 scopus 로고    scopus 로고
    • Naloxone prevents microglia-induced degeneration of dopaminergic substantia nigra neurons in adult rats
    • Lu X., Bing G., and Hagg T. Naloxone prevents microglia-induced degeneration of dopaminergic substantia nigra neurons in adult rats. Neuroscience 97 2 (2000) 285-291
    • (2000) Neuroscience , vol.97 , Issue.2 , pp. 285-291
    • Lu, X.1    Bing, G.2    Hagg, T.3
  • 53
    • 4644250845 scopus 로고    scopus 로고
    • Interleukin-10 attenuates production of HSV-induced inflammatory mediators by human microglia
    • Marques C.P., Hu S., Sheng W., Cheeran M.C., Cox D., and Lokensgard J.R. Interleukin-10 attenuates production of HSV-induced inflammatory mediators by human microglia. Glia 47 4 (2004) 358-366
    • (2004) Glia , vol.47 , Issue.4 , pp. 358-366
    • Marques, C.P.1    Hu, S.2    Sheng, W.3    Cheeran, M.C.4    Cox, D.5    Lokensgard, J.R.6
  • 54
    • 0029003760 scopus 로고
    • Eicosanoids are produced by microglia, not by astrocytes, in rat glial cell cultures
    • Matsuo M., Hamasaki Y., Fujiyama F., and Miyazaki S. Eicosanoids are produced by microglia, not by astrocytes, in rat glial cell cultures. Brain Res 685 1-2 (1995) 201-204
    • (1995) Brain Res , vol.685 , Issue.1-2 , pp. 201-204
    • Matsuo, M.1    Hamasaki, Y.2    Fujiyama, F.3    Miyazaki, S.4
  • 55
    • 0023740773 scopus 로고
    • Rate of cell death in Parkinsonism indicates active neuropathological process
    • McGeer P.L., Itagaki S., Akiyama H., and McGeer E.G. Rate of cell death in Parkinsonism indicates active neuropathological process. Ann Neurol 24 4 (1988) 574-576
    • (1988) Ann Neurol , vol.24 , Issue.4 , pp. 574-576
    • McGeer, P.L.1    Itagaki, S.2    Akiyama, H.3    McGeer, E.G.4
  • 56
    • 0023789193 scopus 로고
    • Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains
    • McGeer P.L., Itagaki S., Boyes B.E., and McGeer E.G. Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains. Neurology 38 8 (1988) 1285-1291
    • (1988) Neurology , vol.38 , Issue.8 , pp. 1285-1291
    • McGeer, P.L.1    Itagaki, S.2    Boyes, B.E.3    McGeer, E.G.4
  • 57
    • 0037436514 scopus 로고    scopus 로고
    • Effects of interleukin-10 on neonatal excitotoxic brain lesions in mice
    • Mesples B., Plaisant F., and Gressens P. Effects of interleukin-10 on neonatal excitotoxic brain lesions in mice. Brain Res Dev Brain Res 141 1-2 (2003) 25-32
    • (2003) Brain Res Dev Brain Res , vol.141 , Issue.1-2 , pp. 25-32
    • Mesples, B.1    Plaisant, F.2    Gressens, P.3
  • 58
    • 0028805463 scopus 로고
    • Induction of prostanoid biosynthesis by bacterial lipopolysaccharide and isoproterenol in rat microglial cultures
    • Minghetti L., and Levi G. Induction of prostanoid biosynthesis by bacterial lipopolysaccharide and isoproterenol in rat microglial cultures. J Neurochem 65 6 (1995) 2690-2698
    • (1995) J Neurochem , vol.65 , Issue.6 , pp. 2690-2698
    • Minghetti, L.1    Levi, G.2
  • 59
    • 0028222824 scopus 로고
    • Apoptosis is induced by 1-methyl-4-phenylpyridinium ion (MPP+) in ventral mesencephalic-striatal co-culture in rat
    • Mochizuki H., Nakamura N., Nishi K., and Mizuno Y. Apoptosis is induced by 1-methyl-4-phenylpyridinium ion (MPP+) in ventral mesencephalic-striatal co-culture in rat. Neurosci Lett 170 1 (1994) 191-194
    • (1994) Neurosci Lett , vol.170 , Issue.1 , pp. 191-194
    • Mochizuki, H.1    Nakamura, N.2    Nishi, K.3    Mizuno, Y.4
  • 60
    • 0030595986 scopus 로고    scopus 로고
    • The soluble form of Fas molecule is elevated in Parkinsonian brain tissues
    • Mogi M., Harada M., Kondo T., Mizuno Y., Narabayashi H., Riederer P., et al. The soluble form of Fas molecule is elevated in Parkinsonian brain tissues. Neurosci Lett 220 3 (1996) 195-198
    • (1996) Neurosci Lett , vol.220 , Issue.3 , pp. 195-198
    • Mogi, M.1    Harada, M.2    Kondo, T.3    Mizuno, Y.4    Narabayashi, H.5    Riederer, P.6
  • 61
    • 0028171374 scopus 로고
    • Interleukin-1 beta, interleukin-6, epidermal growth factor and transforming growth factor-alpha are elevated in the brain from Parkinsonian patients
    • Mogi M., Harada M., Kondo T., Riederer P., Inagaki H., Minami M., et al. Interleukin-1 beta, interleukin-6, epidermal growth factor and transforming growth factor-alpha are elevated in the brain from Parkinsonian patients. Neurosci Lett 180 2 (1994) 147-150
    • (1994) Neurosci Lett , vol.180 , Issue.2 , pp. 147-150
    • Mogi, M.1    Harada, M.2    Kondo, T.3    Riederer, P.4    Inagaki, H.5    Minami, M.6
  • 62
    • 0028178281 scopus 로고
    • Tumor necrosis factor-alpha (TNF-alpha) increases both in the brain and in the cerebrospinal fluid from Parkinsonian patients
    • Mogi M., Harada M., Riederer P., Narabayashi H., Fujita K., and Nagatsu T. Tumor necrosis factor-alpha (TNF-alpha) increases both in the brain and in the cerebrospinal fluid from Parkinsonian patients. Neurosci Lett 165 1-2 (1994) 208-210
    • (1994) Neurosci Lett , vol.165 , Issue.1-2 , pp. 208-210
    • Mogi, M.1    Harada, M.2    Riederer, P.3    Narabayashi, H.4    Fujita, K.5    Nagatsu, T.6
  • 63
    • 0035136359 scopus 로고    scopus 로고
    • Actions of exogenous and endogenous IL-10 on glial responses to bacterial LPS/cytokines
    • Molina-Holgado F., Grencis R., and Rothwell N.J. Actions of exogenous and endogenous IL-10 on glial responses to bacterial LPS/cytokines. Glia 33 2 (2001) 97-106
    • (2001) Glia , vol.33 , Issue.2 , pp. 97-106
    • Molina-Holgado, F.1    Grencis, R.2    Rothwell, N.J.3
  • 65
    • 0034525420 scopus 로고    scopus 로고
    • Changes in cytokines and neurotrophins in Parkinson's disease
    • Nagatsu T., Mogi M., Ichinose H., and Togari A. Changes in cytokines and neurotrophins in Parkinson's disease. J Neural Transm Suppl 60 (2000) 277-290
    • (2000) J Neural Transm Suppl , vol.60 , pp. 277-290
    • Nagatsu, T.1    Mogi, M.2    Ichinose, H.3    Togari, A.4
  • 66
    • 0031775603 scopus 로고    scopus 로고
    • Caspases mediate 6-hydroxydopamine-induced apoptosis but not necrosis in PC12 cells
    • Ochu E.E., Rothwell N.J., and Waters C.M. Caspases mediate 6-hydroxydopamine-induced apoptosis but not necrosis in PC12 cells. J Neurochem 70 6 (1998) 2637-2640
    • (1998) J Neurochem , vol.70 , Issue.6 , pp. 2637-2640
    • Ochu, E.E.1    Rothwell, N.J.2    Waters, C.M.3
  • 67
    • 0031980366 scopus 로고    scopus 로고
    • Long-term effect of VVI pacing on atrial and ventricular function in patients with sick sinus syndrome
    • Paxinos G., Katritsis D., Kakouros S., Toutouzas P., and Camm A.J. Long-term effect of VVI pacing on atrial and ventricular function in patients with sick sinus syndrome. Pacing Clin Electrophysiol 21 4 Pt 1 (1998) 728-734
    • (1998) Pacing Clin Electrophysiol , vol.21 , Issue.4 PART 1 , pp. 728-734
    • Paxinos, G.1    Katritsis, D.2    Kakouros, S.3    Toutouzas, P.4    Camm, A.J.5
  • 68
    • 0031024047 scopus 로고    scopus 로고
    • Differential production of and migratory response to beta chemokines by human microglia and astrocytes
    • Peterson P.K., Hu S., Salak-Johnson J., Molitor T.W., and Chao C.C. Differential production of and migratory response to beta chemokines by human microglia and astrocytes. J Infect Dis 175 2 (1997) 478-481
    • (1997) J Infect Dis , vol.175 , Issue.2 , pp. 478-481
    • Peterson, P.K.1    Hu, S.2    Salak-Johnson, J.3    Molitor, T.W.4    Chao, C.C.5
  • 69
    • 0028860616 scopus 로고
    • Evidence of apoptotic cell death after experimental traumatic brain injury in the rat
    • Rink A., Fung K.M., Trojanowski J.Q., Lee V.M., Neugebauer E., and McIntosh T.K. Evidence of apoptotic cell death after experimental traumatic brain injury in the rat. Am J Pathol 147 6 (1995) 1575-1583
    • (1995) Am J Pathol , vol.147 , Issue.6 , pp. 1575-1583
    • Rink, A.1    Fung, K.M.2    Trojanowski, J.Q.3    Lee, V.M.4    Neugebauer, E.5    McIntosh, T.K.6
  • 71
    • 0032996810 scopus 로고    scopus 로고
    • Interleukin-10 inhibits both production of cytokines and expression of cytokine receptors in microglia
    • Sawada M., Suzumura A., Hosoya H., Marunouchi T., and Nagatsu T. Interleukin-10 inhibits both production of cytokines and expression of cytokine receptors in microglia. J Neurochem 72 4 (1999) 1466-1471
    • (1999) J Neurochem , vol.72 , Issue.4 , pp. 1466-1471
    • Sawada, M.1    Suzumura, A.2    Hosoya, H.3    Marunouchi, T.4    Nagatsu, T.5
  • 72
    • 0014280029 scopus 로고
    • Cerebral atrophy in Parkinsonism
    • Selby G. Cerebral atrophy in Parkinsonism. J Neurol Sci 6 3 (1968) 517-559
    • (1968) J Neurol Sci , vol.6 , Issue.3 , pp. 517-559
    • Selby, G.1
  • 73
    • 0029153012 scopus 로고
    • Tumor necrosis factor alpha upregulates human microglial cell production of interleukin-10 in vitro
    • Sheng W.S., Hu S., Kravitz F.H., Peterson P.K., and Chao C.C. Tumor necrosis factor alpha upregulates human microglial cell production of interleukin-10 in vitro. Clin Diagn Lab Immunol 2 5 (1995) 604-608
    • (1995) Clin Diagn Lab Immunol , vol.2 , Issue.5 , pp. 604-608
    • Sheng, W.S.1    Hu, S.2    Kravitz, F.H.3    Peterson, P.K.4    Chao, C.C.5
  • 74
    • 0026643708 scopus 로고
    • Reactive microglia/macrophages phagocytose amyloid precursor protein produced by neurons following neural damage
    • Shigematsu K., McGeer P.L., Walker D.G., Ishii T., and McGeer E.G. Reactive microglia/macrophages phagocytose amyloid precursor protein produced by neurons following neural damage. J Neurosci Res 31 3 (1992) 443-453
    • (1992) J Neurosci Res , vol.31 , Issue.3 , pp. 443-453
    • Shigematsu, K.1    McGeer, P.L.2    Walker, D.G.3    Ishii, T.4    McGeer, E.G.5
  • 75
    • 0031969578 scopus 로고    scopus 로고
    • TUNEL-positive cells in the substantia nigra of C57BL/6 mice after a single bolus of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
    • [discussion 53]
    • Spooren W.P., Gentsch C., and Wiessner C. TUNEL-positive cells in the substantia nigra of C57BL/6 mice after a single bolus of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Neuroscience 85 2 (1998) 649-651 [discussion 53]
    • (1998) Neuroscience , vol.85 , Issue.2 , pp. 649-651
    • Spooren, W.P.1    Gentsch, C.2    Wiessner, C.3
  • 76
    • 0034615555 scopus 로고    scopus 로고
    • Caspases-controlling intracellular signals by protease zymogen activation
    • Stennicke H.R., and Salvesen G.S. Caspases-controlling intracellular signals by protease zymogen activation. Biochim Biophys Acta 1477 1-2 (2000) 299-306
    • (2000) Biochim Biophys Acta , vol.1477 , Issue.1-2 , pp. 299-306
    • Stennicke, H.R.1    Salvesen, G.S.2
  • 77
    • 0032531980 scopus 로고    scopus 로고
    • Involvement of caspase-like proteinases in apoptosis of neuronal PC12 cells and primary cultured microglia induced by 6-hydroxydopamine
    • Takai N., Nakanishi H., Tanabe K., Nishioku T., Sugiyama T., Fujiwara M., et al. Involvement of caspase-like proteinases in apoptosis of neuronal PC12 cells and primary cultured microglia induced by 6-hydroxydopamine. J Neurosci Res 54 2 (1998) 214-222
    • (1998) J Neurosci Res , vol.54 , Issue.2 , pp. 214-222
    • Takai, N.1    Nakanishi, H.2    Tanabe, K.3    Nishioku, T.4    Sugiyama, T.5    Fujiwara, M.6
  • 78
    • 0030888286 scopus 로고    scopus 로고
    • In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining
    • Tatton N.A., and Kish S.J. In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining. Neuroscience 77 4 (1997) 1037-1048
    • (1997) Neuroscience , vol.77 , Issue.4 , pp. 1037-1048
    • Tatton, N.A.1    Kish, S.J.2
  • 79
    • 0031696403 scopus 로고    scopus 로고
    • A fluorescent double-labeling method to detect and confirm apoptotic nuclei in Parkinson's disease
    • Tatton N.A., Maclean-Fraser A., Tatton W.G., Perl D.P., and Olanow C.W. A fluorescent double-labeling method to detect and confirm apoptotic nuclei in Parkinson's disease. Ann Neurol 44 3 Suppl. 1 (1998) S142-S148
    • (1998) Ann Neurol , vol.44 , Issue.3 SUPPL. 1
    • Tatton, N.A.1    Maclean-Fraser, A.2    Tatton, W.G.3    Perl, D.P.4    Olanow, C.W.5
  • 80
    • 0028965644 scopus 로고
    • Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin
    • Ulevitch R.J., and Tobias P.S. Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin. Annu Rev Immunol 13 (1995) 437-457
    • (1995) Annu Rev Immunol , vol.13 , pp. 437-457
    • Ulevitch, R.J.1    Tobias, P.S.2
  • 82
    • 0030641754 scopus 로고    scopus 로고
    • Understanding Parkinson's disease
    • Youdim M.B., and Riederer P. Understanding Parkinson's disease. Sci Am 276 1 (1997) 52-59
    • (1997) Sci Am , vol.276 , Issue.1 , pp. 52-59
    • Youdim, M.B.1    Riederer, P.2
  • 83
    • 0035795058 scopus 로고    scopus 로고
    • Expression of inducible nitric oxide synthase, interleukin-1 and caspase-1 in HIV-1 encephalitis
    • Zhao M.L., Kim M.O., Morgello S., and Lee S.C. Expression of inducible nitric oxide synthase, interleukin-1 and caspase-1 in HIV-1 encephalitis. J Neuroimmunol 115 1-2 (2001) 182-191
    • (2001) J Neuroimmunol , vol.115 , Issue.1-2 , pp. 182-191
    • Zhao, M.L.1    Kim, M.O.2    Morgello, S.3    Lee, S.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.