-
1
-
-
0030038809
-
Scavenging of Alzheimer's amyloid beta-protein by microglia in culture
-
Ard MD, Cole GM, Wei J, Mehrle AP, Fratkin JD. Scavenging of Alzheimer's amyloid beta-protein by microglia in culture. J Neurosci Res 1996; 43: 190-202.
-
(1996)
J Neurosci Res
, vol.43
, pp. 190-202
-
-
Ard, M.D.1
Cole, G.M.2
Wei, J.3
Mehrle, A.P.4
Fratkin, J.D.5
-
2
-
-
0033527637
-
Uptake, degradation, and release of fibrillar and soluble forms of Alzheimer's amyloid beta-peptide by microglial cells
-
Chung H, Brazil MI, Soe TT, Maxfield FR. Uptake, degradation, and release of fibrillar and soluble forms of Alzheimer's amyloid beta-peptide by microglial cells. J Biol Chem 1999; 274: 32301-8.
-
(1999)
J Biol Chem
, vol.274
, pp. 32301-32308
-
-
Chung, H.1
Brazil, M.I.2
Soe, T.T.3
Maxfield, F.R.4
-
3
-
-
0029803744
-
Evidence that the 42- and 40-amino acid forms of amyloid beta protein are generated from the beta-amyloid precursor protein by different protease activities
-
Citron M, Diehl TS, Gordon G, Biere AL, Seubert P, Selkoe DJ. Evidence that the 42- and 40-amino acid forms of amyloid beta protein are generated from the beta-amyloid precursor protein by different protease activities. Proc Natl Acad Sci USA 1996; 93: 13170-5.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 13170-13175
-
-
Citron, M.1
Diehl, T.S.2
Gordon, G.3
Biere, A.L.4
Seubert, P.5
Selkoe, D.J.6
-
4
-
-
33947621993
-
Assessing nest building in mice
-
Deacon RM. Assessing nest building in mice. Nat Protoc 2006; 1: 1117-9.
-
(2006)
Nat Protoc
, vol.1
, pp. 1117-1119
-
-
Deacon, R.M.1
-
5
-
-
0023809230
-
Alzheimer's disease. A double-labeling immunohistochemical study of senile plaques
-
Dickson DW, Farlo J, Davies P, Crystal H, Fuld P, Yen SH. Alzheimer's disease. A double-labeling immunohistochemical study of senile plaques. Am J Pathol 1988; 132: 86-101.
-
(1988)
Am J Pathol
, vol.132
, pp. 86-101
-
-
Dickson, D.W.1
Farlo, J.2
Davies, P.3
Crystal, H.4
Fuld, P.5
Yen, S.H.6
-
6
-
-
34147115541
-
Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease
-
El Khoury J, Toft M, Hickman SE, Means TK, Terada K, Geula C, et al. Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease. Nat Med 2007; 13: 432-8.
-
(2007)
Nat Med
, vol.13
, pp. 432-438
-
-
El Khoury, J.1
Toft, M.2
Hickman, S.E.3
Means, T.K.4
Terada, K.5
Geula, C.6
-
7
-
-
0031974406
-
Microglial response to amyloid plaques in APPsw transgenic mice
-
Frautschy SA, Yang F, Irrizarry M, Hyman B, Saido TC, Hsiao K, et al. Microglial response to amyloid plaques in APPsw transgenic mice. Am J Pathol 1998; 152: 307-17.
-
(1998)
Am J Pathol
, vol.152
, pp. 307-317
-
-
Frautschy, S.A.1
Yang, F.2
Irrizarry, M.3
Hyman, B.4
Saido, T.C.5
Hsiao, K.6
-
8
-
-
0029811105
-
Specific domains of beta-amyloid from Alzheimer plaque elicit neuron killing in human microglia
-
Giulian D, Haverkamp LJ, Yu JH, Karshin W, Tom D, Li J, et al. Specific domains of beta-amyloid from Alzheimer plaque elicit neuron killing in human microglia. J Neurosci 1996; 16: 6021-37.
-
(1996)
J Neurosci
, vol.16
, pp. 6021-6037
-
-
Giulian, D.1
Haverkamp, L.J.2
Yu, J.H.3
Karshin, W.4
Tom, D.5
Li, J.6
-
9
-
-
0024211168
-
Colony-stimulating factors as promoters of ameboid microglia
-
Giulian D, Ingeman JE. Colony-stimulating factors as promoters of ameboid microglia. J Neurosci 1988; 8: 4707-17.
-
(1988)
J Neurosci
, vol.8
, pp. 4707-4717
-
-
Giulian, D.1
Ingeman, J.E.2
-
10
-
-
0024573330
-
Demonstration of microglial cells in and around senile (neuritic) plaques in the Alzheimer brain. An immunohistochem-ical study using a novel monoclonal antibody
-
Haga S, Akai K, Ishii T. Demonstration of microglial cells in and around senile (neuritic) plaques in the Alzheimer brain. An immunohistochem-ical study using a novel monoclonal antibody. Acta Neuropathol 1989; 77: 569-75.
-
(1989)
Acta Neuropathol
, vol.77
, pp. 569-575
-
-
Haga, S.1
Akai, K.2
Ishii, T.3
-
11
-
-
46249090513
-
Colony-stimulating factors in inflammation and autoimmu-nity
-
Hamilton JA. Colony-stimulating factors in inflammation and autoimmu-nity. Nat Rev Immunol 2008; 8: 533-44.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 533-544
-
-
Hamilton, J.A.1
-
12
-
-
21544468846
-
Treatment with an amyloid-beta antibody ameliorates plaque load, learning deficits, and hippocampal long-term potentiation in a mouse model of Alzheimer's disease
-
Hartman RE, Izumi Y, Bales KR, Paul SM, Wozniak DF, Holtzman DM. Treatment with an amyloid-beta antibody ameliorates plaque load, learning deficits, and hippocampal long-term potentiation in a mouse model of Alzheimer's disease. J Neurosci 2005; 25: 6213-20.
-
(2005)
J Neurosci
, vol.25
, pp. 6213-6220
-
-
Hartman, R.E.1
Izumi, Y.2
Bales, K.R.3
Paul, S.M.4
Wozniak, D.F.5
Holtzman, D.M.6
-
13
-
-
0024436506
-
Relationship of microglia and astrocytes to amyloid deposits of Alzheimer disease
-
Itagaki S, McGeer PL, Akiyama H, Zhu S, Selkoe D. Relationship of microglia and astrocytes to amyloid deposits of Alzheimer disease. J Neuroimmunol 1989; 24: 173-82.
-
(1989)
J Neuroimmunol
, vol.24
, pp. 173-182
-
-
Itagaki, S.1
McGeer, P.L.2
Akiyama, H.3
Zhu, S.4
Selkoe, D.5
-
14
-
-
25444495866
-
Microglia in health and disease
-
Kim SU, de Vellis J. Microglia in health and disease. J Neurosci Res 2005; 81: 302-13.
-
(2005)
J Neurosci Res
, vol.81
, pp. 302-313
-
-
Kim, S.U.1
de Vellis, J.2
-
15
-
-
33645038471
-
A specific amyloid-beta protein assembly in the brain impairs memory
-
Lesne S, Koh MT, Kotilinek L, Kayed R, Glabe CG, Yang A, et al. A specific amyloid-beta protein assembly in the brain impairs memory. Nature 2006; 440: 352-7.
-
(2006)
Nature
, vol.440
, pp. 352-357
-
-
Lesne, S.1
Koh, M.T.2
Kotilinek, L.3
Kayed, R.4
Glabe, C.G.5
Yang, A.6
-
16
-
-
23444448277
-
LPS receptor (CD14): A receptor for phagocytosis of Alzheimer's amyloid peptide
-
Liu Y, Walter S, Stagi M, Cherny D, Letiembre M, Schulz-Schaeffer W, et al. LPS receptor (CD14): a receptor for phagocytosis of Alzheimer's amyloid peptide. Brain 2005; 128: 1778-89.
-
(2005)
Brain
, vol.128
, pp. 1778-1789
-
-
Liu, Y.1
Walter, S.2
Stagi, M.3
Cherny, D.4
Letiembre, M.5
Schulz-Schaeffer, W.6
-
17
-
-
34247264399
-
Activation of microglia acidifies lysosomes and leads to degradation of Alzheimer amyloid fibrils
-
Majumdar A, Cruz D, Asamoah N, Buxbaum A, Sohar I, Lobel P, et al. Activation of microglia acidifies lysosomes and leads to degradation of Alzheimer amyloid fibrils. Mol Biol Cell 2007; 18: 1490-6.
-
(2007)
Mol Biol Cell
, vol.18
, pp. 1490-1496
-
-
Majumdar, A.1
Cruz, D.2
Asamoah, N.3
Buxbaum, A.4
Sohar, I.5
Lobel, P.6
-
18
-
-
11844255779
-
Bone-marrow-derived cells contribute to the recruitment of microglial cells in response to beta-amyloid deposition in APP/PS1 double transgenic Alzheimer mice
-
Malm TM, Koistinaho M, Parepalo M, Vatanen T, Ooka A, Karlsson S, et al. Bone-marrow-derived cells contribute to the recruitment of microglial cells in response to beta-amyloid deposition in APP/PS1 double transgenic Alzheimer mice. Neurobiol Dis 2005; 18: 134-42.
-
(2005)
Neurobiol Dis
, vol.18
, pp. 134-142
-
-
Malm, T.M.1
Koistinaho, M.2
Parepalo, M.3
Vatanen, T.4
Ooka, A.5
Karlsson, S.6
-
19
-
-
3943092621
-
Pathways towards and away from Alzheimer's disease
-
Mattson MP. Pathways towards and away from Alzheimer's disease. Nature 2004; 430: 631-9.
-
(2004)
Nature
, vol.430
, pp. 631-639
-
-
Mattson, M.P.1
-
20
-
-
0035839643
-
Overexpression of macrophage colony-stimulating factor receptor on microglial cells induces an inflammatory response
-
Mitrasinovic OM, Perez GV, Zhao F, Lee YL, Poon C, Murphy GM Jr. Overexpression of macrophage colony-stimulating factor receptor on microglial cells induces an inflammatory response. J Biol Chem 2001; 276: 30142-9.
-
(2001)
J Biol Chem
, vol.276
, pp. 30142-30149
-
-
Mitrasinovic, O.M.1
Perez, G.V.2
Zhao, F.3
Lee, Y.L.4
Poon, C.5
Murphy Jr., G.M.6
-
21
-
-
0242268945
-
Immunotherapeutic approaches to Alzheimer's disease
-
Monsonego A, Weiner HL. Immunotherapeutic approaches to Alzheimer's disease. Science 2003; 302: 834-8.
-
(2003)
Science
, vol.302
, pp. 834-838
-
-
Monsonego, A.1
Weiner, H.L.2
-
22
-
-
84984755327
-
A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease
-
Morgan D, Diamond DM, Gottschall PE, Ugen KE, Dickey C, Hardy J, et al. A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease. Nature 2000; 408: 982-5.
-
(2000)
Nature
, vol.408
, pp. 982-985
-
-
Morgan, D.1
Diamond, D.M.2
Gottschall, P.E.3
Ugen, K.E.4
Dickey, C.5
Hardy, J.6
-
23
-
-
3542996239
-
Macrophage colony-stimulating factor augments beta-amyloid-induced interleukin-1, interleukin-6, and nitric oxide production by microglial cells
-
Murphy GM Jr, Yang L, Cordell B. Macrophage colony-stimulating factor augments beta-amyloid-induced interleukin-1, interleukin-6, and nitric oxide production by microglial cells. J Biol Chem 1998; 273: 20967-71.
-
(1998)
J Biol Chem
, vol.273
, pp. 20967-20971
-
-
Murphy Jr, G.M.1
Yang, L.2
Cordell, B.3
-
24
-
-
0034492957
-
Expression of macrophage colony-stimulating factor receptor is increased in the AbetaPP(V717F) transgenic mouse model of Alzheimer's disease
-
Murphy GM Jr, Zhao F, Yang L, Cordell B. Expression of macrophage colony-stimulating factor receptor is increased in the AbetaPP(V717F) transgenic mouse model of Alzheimer's disease. Am J Pathol 2000; 157: 895-904.
-
(2000)
Am J Pathol
, vol.157
, pp. 895-904
-
-
Murphy Jr, G.M.1
Zhao, F.2
Yang, L.3
Cordell, B.4
-
25
-
-
0036518997
-
Innate immunity: The missing link in neuroprotection and neurodegeneration?
-
Nguyen MD, Julien JP, Rivest S. Innate immunity: the missing link in neuroprotection and neurodegeneration? Nat Rev Neurosci 2002; 3: 216-27.
-
(2002)
Nat Rev Neurosci
, vol.3
, pp. 216-227
-
-
Nguyen, M.D.1
Julien, J.P.2
Rivest, S.3
-
26
-
-
0037393454
-
Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: A case report
-
Nicoll JA, Wilkinson D, Holmes C, Steart P, Markham H, Weller RO. Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report. Nat Med 2003; 9: 448-52.
-
(2003)
Nat Med
, vol.9
, pp. 448-452
-
-
Nicoll, J.A.1
Wilkinson, D.2
Holmes, C.3
Steart, P.4
Markham, H.5
Weller, R.O.6
-
27
-
-
0030664076
-
Slow degradation of aggregates of the Alzheimer's disease amyloid beta-protein by microglial cells
-
Paresce DM, Chung H, Maxfield FR. Slow degradation of aggregates of the Alzheimer's disease amyloid beta-protein by microglial cells. J Biol Chem 1997; 272: 29390-7.
-
(1997)
J Biol Chem
, vol.272
, pp. 29390-29397
-
-
Paresce, D.M.1
Chung, H.2
Maxfield, F.R.3
-
28
-
-
0026470167
-
MHC class II-positive micro-glia in human brain: Association with Alzheimer lesions
-
Perlmutter LS, Scott SA, Barron E, Chui HC. MHC class II-positive micro-glia in human brain: association with Alzheimer lesions. J Neurosci Res 1992; 33: 549-58.
-
(1992)
J Neurosci Res
, vol.33
, pp. 549-558
-
-
Perlmutter, L.S.1
Scott, S.A.2
Barron, E.3
Chui, H.C.4
-
29
-
-
35948933394
-
Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins
-
Ray S, Britschgi M, Herbert C, Takeda-Uchimura Y, Boxer A, Blennow K, et al. Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins. Nat Med 2007; 13: 1359-62.
-
(2007)
Nat Med
, vol.13
, pp. 1359-1362
-
-
Ray, S.1
Britschgi, M.2
Herbert, C.3
Takeda-Uchimura, Y.4
Boxer, A.5
Blennow, K.6
-
30
-
-
45949106077
-
Toll-like receptor 2 acts as a natural innate immune receptor to clear amyloid beta 1-42 and delay the cognitive decline in a mouse model of Alzheimer's disease
-
Richard KL, Filali M, Prefontaine P, Rivest S. Toll-like receptor 2 acts as a natural innate immune receptor to clear amyloid beta 1-42 and delay the cognitive decline in a mouse model of Alzheimer's disease. J Neurosci 2008; 28: 5784-93.
-
(2008)
J Neurosci
, vol.28
, pp. 5784-5793
-
-
Richard, K.L.1
Filali, M.2
Prefontaine, P.3
Rivest, S.4
-
31
-
-
0031255352
-
Behavioral and functional analysis of mouse phenotype: SHIRPA, a proposed protocol for comprehensive phenotype assessment
-
Rogers DC, Fisher EM, Brown SD, Peters J, Hunter AJ, Martin JE. Behavioral and functional analysis of mouse phenotype: SHIRPA, a proposed protocol for comprehensive phenotype assessment. Mamm Genome 1997; 8: 711-13.
-
(1997)
Mamm Genome
, vol.8
, pp. 711-713
-
-
Rogers, D.C.1
Fisher, E.M.2
Brown, S.D.3
Peters, J.4
Hunter, A.J.5
Martin, J.E.6
-
32
-
-
0034814056
-
Microglial chemotaxis, activation, and phagocytosis of amyloid beta-peptide as linked phenomena in Alzheimer's disease
-
Rogers J, Lue LF. Microglial chemotaxis, activation, and phagocytosis of amyloid beta-peptide as linked phenomena in Alzheimer's disease. Neurochem Int 2001; 39: 333-40.
-
(2001)
Neurochem Int
, vol.39
, pp. 333-340
-
-
Rogers, J.1
Lue, L.F.2
-
33
-
-
0036849021
-
Microglia and inflammatory mechanisms in the clearance of amyloid beta peptide
-
Rogers J, Strohmeyer R, Kovelowski CJ, Li R. Microglia and inflammatory mechanisms in the clearance of amyloid beta peptide. Glia 2002; 40: 260-9.
-
(2002)
Glia
, vol.40
, pp. 260-269
-
-
Rogers, J.1
Strohmeyer, R.2
Kovelowski, C.J.3
Li, R.4
-
34
-
-
0035933106
-
Developmental plasticity of CNS micro-glia
-
Santambrogio L, Belyanskaya SL, Fischer FR, Cipriani B, Brosnan CF, Ricciardi-Castagnoli P, et al. Developmental plasticity of CNS micro-glia. Proc Natl Acad Sci USA 2001; 98: 6295-300.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 6295-6300
-
-
Santambrogio, L.1
Belyanskaya, S.L.2
Fischer, F.R.3
Cipriani, B.4
Brosnan, C.F.5
Ricciardi-Castagnoli, P.6
-
35
-
-
0035066332
-
Alzheimer's disease: Genes, proteins, and therapy
-
Selkoe DJ. Alzheimer's disease: genes, proteins, and therapy. Physiol Rev 2001; 81: 741-66.
-
(2001)
Physiol Rev
, vol.81
, pp. 741-766
-
-
Selkoe, D.J.1
-
36
-
-
0030757323
-
Neuritic plaque evolution in Alzheimer's disease is accompanied by transition of activated microglia from primed to enlarged to phagocytic forms
-
Sheng JG, Mrak RE, Griffin WS. Neuritic plaque evolution in Alzheimer's disease is accompanied by transition of activated microglia from primed to enlarged to phagocytic forms. Acta Neuropathol 1997; 94: 1-5.
-
(1997)
Acta Neuropathol
, vol.94
, pp. 1-5
-
-
Sheng, J.G.1
Mrak, R.E.2
Griffin, W.S.3
-
37
-
-
32344440522
-
Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease
-
Simard AR, Soulet D, Gowing G, Julien JP, Rivest S. Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease. Neuron 2006; 49: 489-502.
-
(2006)
Neuron
, vol.49
, pp. 489-502
-
-
Simard, A.R.1
Soulet, D.2
Gowing, G.3
Julien, J.P.4
Rivest, S.5
-
38
-
-
30644480429
-
Tumor necrosis factor alpha but not interleukin 1 beta mediates neuroprotection in response to acute nitric oxide exci-totoxicity
-
Turrin NP, Rivest S. Tumor necrosis factor alpha but not interleukin 1 beta mediates neuroprotection in response to acute nitric oxide exci-totoxicity. J Neurosci 2006; 26: 143-51.
-
(2006)
J Neurosci
, vol.26
, pp. 143-151
-
-
Turrin, N.P.1
Rivest, S.2
-
39
-
-
25444505871
-
Investigations with cultured human microglia on pathogenic mechanisms of Alzheimer's disease and other neurodegen-erative diseases
-
Walker DG, Lue LF. Investigations with cultured human microglia on pathogenic mechanisms of Alzheimer's disease and other neurodegen-erative diseases. J Neurosci Res 2005; 81: 412-25.
-
(2005)
J Neurosci Res
, vol.81
, pp. 412-425
-
-
Walker, D.G.1
Lue, L.F.2
-
40
-
-
4444323422
-
Cells of monocyte/microglial lineage are involved in both microvessel amyloidosis and fibrillar plaque formation in APPsw tg mice
-
Wegiel J, Imaki H, Wang KC, Rubenstein R. Cells of monocyte/microglial lineage are involved in both microvessel amyloidosis and fibrillar plaque formation in APPsw tg mice. Brain Res 2004; 1022: 19-29.
-
(2004)
Brain Res
, vol.1022
, pp. 19-29
-
-
Wegiel, J.1
Imaki, H.2
Wang, K.C.3
Rubenstein, R.4
-
41
-
-
0035054886
-
The role of microglial cells and astrocytes in fibrillar plaque evolution in transgenic APP(SW) mice
-
Wegiel J, Wang KC, Imaki H, Rubenstein R, Wronska A, Osuchowski M, et al. The role of microglial cells and astrocytes in fibrillar plaque evolution in transgenic APP(SW) mice. Neurobiol Aging 2001; 22: 49-61.
-
(2001)
Neurobiol Aging
, vol.22
, pp. 49-61
-
-
Wegiel, J.1
Wang, K.C.2
Imaki, H.3
Rubenstein, R.4
Wronska, A.5
Osuchowski, M.6
-
42
-
-
0038790267
-
Origin and turnover of microglial cells in fibrillar plaques of APPsw transgenic mice
-
Wegiel J, Imaki H, Wang KC, Wronska A, Osuchowski M, Rubenstein R. Origin and turnover of microglial cells in fibrillar plaques of APPsw transgenic mice. Acta Neuropathol 2003; 105: 393-402.
-
(2003)
Acta Neuropathol
, vol.105
, pp. 393-402
-
-
Wegiel, J.1
Imaki, H.2
Wang, K.C.3
Wronska, A.4
Osuchowski, M.5
Rubenstein, R.6
|