메뉴 건너뛰기




Volumn 174, Issue 11, 2017, Pages 1378-1394

Potential role of bioactive peptides in prevention and treatment of chronic diseases: a narrative review

Author keywords

[No Author keywords available]

Indexed keywords

OCTAPEPTIDE; PEPTIDE DERIVATIVE; PEPTIDE;

EID: 84990048315     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.13608     Document Type: Review
Times cited : (266)

References (129)
  • 1
    • 73249119117 scopus 로고    scopus 로고
    • Casein-derived tripeptide, Val-Pro-Pro (VPP), modulates monocyte adhesion to vascular endothelium
    • Aihara K, Ishii H, Yoshida M (2009). Casein-derived tripeptide, Val-Pro-Pro (VPP), modulates monocyte adhesion to vascular endothelium. J Atheroscler Thromb 16: 594–603.
    • (2009) J Atheroscler Thromb , vol.16 , pp. 594-603
    • Aihara, K.1    Ishii, H.2    Yoshida, M.3
  • 9
    • 84928492349 scopus 로고    scopus 로고
    • Antihypertensive peptides from food proteins. Annu
    • Aluko RE (2015). Antihypertensive peptides from food proteins. Annu. Rev Food Sci Technol 6: 235–262.
    • (2015) Rev Food Sci Technol , vol.6 , pp. 235-262
    • Aluko, R.E.1
  • 10
    • 0031060389 scopus 로고    scopus 로고
    • Cytotoxic peptides hemiasterlin, hemiasterlin A and hemiasterlin B induce mitotic arrest and abnormal spindle formation
    • Anderson HJ, Coleman JE, Andersen RJ, Roberge M (1997). Cytotoxic peptides hemiasterlin, hemiasterlin A and hemiasterlin B induce mitotic arrest and abnormal spindle formation. Cancer Chemother Pharmacol 39: 223–226.
    • (1997) Cancer Chemother Pharmacol , vol.39 , pp. 223-226
    • Anderson, H.J.1    Coleman, J.E.2    Andersen, R.J.3    Roberge, M.4
  • 12
    • 0034044285 scopus 로고    scopus 로고
    • Antitumorigenic effects of several food proteins in a rat model with colon cancer and their reverse correlation with plasma bile acid concentration
    • Azuma N, Suda H, Iwasaki H, Yamagata N, Saeki T, Kanamoto R et al. (2000). Antitumorigenic effects of several food proteins in a rat model with colon cancer and their reverse correlation with plasma bile acid concentration. J Nutr Sci Vitaminol 46: 91–96.
    • (2000) J Nutr Sci Vitaminol , vol.46 , pp. 91-96
    • Azuma, N.1    Suda, H.2    Iwasaki, H.3    Yamagata, N.4    Saeki, T.5    Kanamoto, R.6
  • 13
    • 0025352537 scopus 로고
    • Dolastatin 10, a powerful cytostatic peptide derived from a marine animal. Inhibition of tubulin polymerization mediated through the vinca alkaloid binding domain
    • Bai R, Pettit GR, Hamel E (1990). Dolastatin 10, a powerful cytostatic peptide derived from a marine animal. Inhibition of tubulin polymerization mediated through the vinca alkaloid binding domain. Biochem Pharmacol 39: 1941–1949.
    • (1990) Biochem Pharmacol , vol.39 , pp. 1941-1949
    • Bai, R.1    Pettit, G.R.2    Hamel, E.3
  • 14
    • 84940453782 scopus 로고    scopus 로고
    • Bioactive peptides of animal origin: a review
    • Bhat ZF, Kumar S, Bhat HF (2015). Bioactive peptides of animal origin: a review. J Food Sci Technol 52: 5377–5392.
    • (2015) J Food Sci Technol , vol.52 , pp. 5377-5392
    • Bhat, Z.F.1    Kumar, S.2    Bhat, H.F.3
  • 17
    • 84960971302 scopus 로고    scopus 로고
    • Nutraceuticals with clinically detectable blood pressure lowering effect: a review of available randomized clinical trials and their meta-analyses
    • Borghi C, Cicero AF (2016). Nutraceuticals with clinically detectable blood pressure lowering effect: a review of available randomized clinical trials and their meta-analyses. Br J Clin Pharmacol. doi:10.1111/bcp.12902.
    • (2016) Br J Clin Pharmacol
    • Borghi, C.1    Cicero, A.F.2
  • 18
    • 84963846238 scopus 로고    scopus 로고
    • Soy protein compared with milk protein in a western diet increases gut microbial diversity and reduces serum lipids in golden Syrian hamsters
    • Butteiger DN, Hibberd AA, McGraw NJ, Napawan N, Hall-Porter JM, Krul ES (2016). Soy protein compared with milk protein in a western diet increases gut microbial diversity and reduces serum lipids in golden Syrian hamsters. J Nutr 146: 697–705.
    • (2016) J Nutr , vol.146 , pp. 697-705
    • Butteiger, D.N.1    Hibberd, A.A.2    McGraw, N.J.3    Napawan, N.4    Hall-Porter, J.M.5    Krul, E.S.6
  • 19
    • 84867090699 scopus 로고    scopus 로고
    • RGD-peptide lunasin inhibits Akt-mediated NF-κB activation in human macrophages through interaction with the αVβ3 integrin
    • Cam A, de Mejia EG (2012). RGD-peptide lunasin inhibits Akt-mediated NF-κB activation in human macrophages through interaction with the αVβ3 integrin. Mol Nutr Food Res 56: 1569–1581.
    • (2012) Mol Nutr Food Res , vol.56 , pp. 1569-1581
    • Cam, A.1    de Mejia, E.G.2
  • 20
    • 84893724700 scopus 로고    scopus 로고
    • Food-derived bioactive peptides on inflammation and oxidative stress
    • Chakrabarti S, Jahandideh F, Wu J (2014). Food-derived bioactive peptides on inflammation and oxidative stress. Biomed Res Int 2014: 608979.
    • (2014) Biomed Res Int , vol.2014 , pp. 608979
    • Chakrabarti, S.1    Jahandideh, F.2    Wu, J.3
  • 22
    • 22844434892 scopus 로고    scopus 로고
    • Bowman-Birk inhibitor abates proteasome function and suppresses the proliferation of MCF7 breast cancer cells through accumulation of MAP kinase phosphatase-1
    • Chen YW, Huang SC, Lin-Shiau SY, Lin JK (2005). Bowman-Birk inhibitor abates proteasome function and suppresses the proliferation of MCF7 breast cancer cells through accumulation of MAP kinase phosphatase-1. Carcinogenesis 26: 1296–1306.
    • (2005) Carcinogenesis , vol.26 , pp. 1296-1306
    • Chen, Y.W.1    Huang, S.C.2    Lin-Shiau, S.Y.3    Lin, J.K.4
  • 23
    • 84938318652 scopus 로고    scopus 로고
    • Marine peptides: bioactivities and applications
    • Cheung RC, Ng TB, Wong JH (2015). Marine peptides: bioactivities and applications. Mar Drugs 13: 4006–4043.
    • (2015) Mar Drugs , vol.13 , pp. 4006-4043
    • Cheung, R.C.1    Ng, T.B.2    Wong, J.H.3
  • 24
    • 38049025210 scopus 로고    scopus 로고
    • Cholesterol lowering mechanism of soybean protein hydrolysate
    • Cho SJ, Juillerat MA, Lee CH (2007). Cholesterol lowering mechanism of soybean protein hydrolysate. J Agric Food Chem 55: 10599–10604.
    • (2007) J Agric Food Chem , vol.55 , pp. 10599-10604
    • Cho, S.J.1    Juillerat, M.A.2    Lee, C.H.3
  • 25
    • 84940465204 scopus 로고    scopus 로고
    • Nutraceuticals and blood pressure control: results from clinical trials and meta-analyses
    • Cicero AF, Colletti A (2015a). Nutraceuticals and blood pressure control: results from clinical trials and meta-analyses. High Blood Press Cardiovasc Prev 22: 203–213.
    • (2015) High Blood Press Cardiovasc Prev , vol.22 , pp. 203-213
    • Cicero, A.F.1    Colletti, A.2
  • 26
    • 84982180019 scopus 로고    scopus 로고
    • Combinations of phytomedicines with different lipid lowering activity for dyslipidemia management: the available clinical data
    • Nov 10
    • Cicero AF, Colletti A (2015b). Combinations of phytomedicines with different lipid lowering activity for dyslipidemia management: the available clinical data. Phytomedicine Nov 10. pii: S0944-7113(15)00330-X. doi:10.1016/j.phymed.2015.10.011.
    • (2015) Phytomedicine
    • Cicero, A.F.1    Colletti, A.2
  • 27
    • 79959288378 scopus 로고    scopus 로고
    • Blood pressure lowering effect of lactotripeptides assumed as functional foods: a meta-analysis of current available clinical trials
    • Cicero AF, Gerocarni B, Laghi L, Borghi C (2011a). Blood pressure lowering effect of lactotripeptides assumed as functional foods: a meta-analysis of current available clinical trials. J Hum Hypertens 25: 425–436.
    • (2011) J Hum Hypertens , vol.25 , pp. 425-436
    • Cicero, A.F.1    Gerocarni, B.2    Laghi, L.3    Borghi, C.4
  • 28
    • 80052507804 scopus 로고    scopus 로고
    • Lactotripeptides effect on office and 24-h ambulatory blood pressure, blood pressure stress response, pulse wave velocity and cardiac output in patients with high-normal blood pressure or first-degree hypertension: a randomized double-blind clinical trial
    • Cicero AF, Rosticci M, Gerocarni B, Bacchelli S, Veronesi M, Strocchi E et al. (2011b). Lactotripeptides effect on office and 24-h ambulatory blood pressure, blood pressure stress response, pulse wave velocity and cardiac output in patients with high-normal blood pressure or first-degree hypertension: a randomized double-blind clinical trial. Hypertens Res 34: 1035–1040.
    • (2011) Hypertens Res , vol.34 , pp. 1035-1040
    • Cicero, A.F.1    Rosticci, M.2    Gerocarni, B.3    Bacchelli, S.4    Veronesi, M.5    Strocchi, E.6
  • 29
    • 84876557415 scopus 로고    scopus 로고
    • Do the lactotripeptides isoleucine–proline–proline and valine–proline–proline reduce systolic blood pressure in European subjects? A meta-analysis of randomized controlled trials
    • Cicero AF, Aubin F, Azais-Braesco V, Borghi C (2013). Do the lactotripeptides isoleucine–proline–proline and valine–proline–proline reduce systolic blood pressure in European subjects? A meta-analysis of randomized controlled trials. Am J Hypertens 26: 442–449.
    • (2013) Am J Hypertens , vol.26 , pp. 442-449
    • Cicero, A.F.1    Aubin, F.2    Azais-Braesco, V.3    Borghi, C.4
  • 30
    • 84961789009 scopus 로고    scopus 로고
    • Effect of lactotripeptides (isoleucine-proline-proline/valine-proline-proline) on blood pressure and arterial stiffness changes in subjects with suboptimal blood pressure control and metabolic syndrome: A double-blind, randomized, crossover clinical trial
    • Cicero AF, Colletti A, Rosticci M, Cagnati M, Urso R, Giovannini M et al. (2016). Effect of lactotripeptides (isoleucine-proline-proline/valine-proline-proline) on blood pressure and arterial stiffness changes in subjects with suboptimal blood pressure control and metabolic syndrome: A double-blind, randomized, crossover clinical trial. Metab Syndr Relat Disord 14: 161–166.
    • (2016) Metab Syndr Relat Disord , vol.14 , pp. 161-166
    • Cicero, A.F.1    Colletti, A.2    Rosticci, M.3    Cagnati, M.4    Urso, R.5    Giovannini, M.6
  • 32
    • 0033197916 scopus 로고    scopus 로고
    • Lactoferrin inhibits G1 cyclin-dependent kinases during growth arrest of human breast carcinoma cells
    • Damiens E, Yazidi I, Mazurier J, Duthile I, Spik G, Boilly-Marer Y (1999). Lactoferrin inhibits G1 cyclin-dependent kinases during growth arrest of human breast carcinoma cells. J Cell Biochem 74: 486–498.
    • (1999) J Cell Biochem , vol.74 , pp. 486-498
    • Damiens, E.1    Yazidi, I.2    Mazurier, J.3    Duthile, I.4    Spik, G.5    Boilly-Marer, Y.6
  • 33
    • 77957604071 scopus 로고    scopus 로고
    • The role of nutraceutical proteins and peptides in apoptosis, angiogenesis, and metastasis of cancer cells
    • de Mejía EG, Dia VP (2010). The role of nutraceutical proteins and peptides in apoptosis, angiogenesis, and metastasis of cancer cells. Cancer Metast Rev 29: 511–528.
    • (2010) Cancer Metast Rev , vol.29 , pp. 511-528
    • de Mejía, E.G.1    Dia, V.P.2
  • 34
    • 77649321216 scopus 로고    scopus 로고
    • Lunasin, with an arginine-glycine-aspartic acid motif, causes apoptosis to L1210 leukemia cells by activation of caspase-3
    • de Mejia EG, Wang W, Dia VP (2010). Lunasin, with an arginine-glycine-aspartic acid motif, causes apoptosis to L1210 leukemia cells by activation of caspase-3. Mol Nutr Food Res 54: 406–414.
    • (2010) Mol Nutr Food Res , vol.54 , pp. 406-414
    • de Mejia, E.G.1    Wang, W.2    Dia, V.P.3
  • 35
    • 84883742239 scopus 로고    scopus 로고
    • Lactotransferrin acts as a tumor suppressor in nasopharyngeal carcinoma by repressing AKT through multiple mechanisms
    • Deng M, Zhang W, Tang H, Ye Q, Liao Q, Zhou Y et al. (2013). Lactotransferrin acts as a tumor suppressor in nasopharyngeal carcinoma by repressing AKT through multiple mechanisms. Oncogene 32: 4273–4283.
    • (2013) Oncogene , vol.32 , pp. 4273-4283
    • Deng, M.1    Zhang, W.2    Tang, H.3    Ye, Q.4    Liao, Q.5    Zhou, Y.6
  • 36
    • 82655173826 scopus 로고    scopus 로고
    • Lunasin potentiates the effect of oxaliplatin preventing outgrowth of colon cancer metastasis, binds to α5β1 integrin and suppresses FAK/ERK/NF-κB signaling
    • Dia VP, de Mejia EG (2011). Lunasin potentiates the effect of oxaliplatin preventing outgrowth of colon cancer metastasis, binds to α5β1 integrin and suppresses FAK/ERK/NF-κB signaling. Cancer Lett 313: 167–180.
    • (2011) Cancer Lett , vol.313 , pp. 167-180
    • Dia, V.P.1    de Mejia, E.G.2
  • 37
    • 77953622693 scopus 로고    scopus 로고
    • Lunasin promotes apoptosis in human colon cancer cells by mitochondrial pathway activation and induction of nuclear clusterin expression
    • Dia VP, Mejia EG (2010). Lunasin promotes apoptosis in human colon cancer cells by mitochondrial pathway activation and induction of nuclear clusterin expression. Cancer Lett 295: 44–53.
    • (2010) Cancer Lett , vol.295 , pp. 44-53
    • Dia, V.P.1    Mejia, E.G.2
  • 38
    • 58149522343 scopus 로고    scopus 로고
    • Isolation, purification and characterization of lunasin from defatted soybean flour and in vitro evaluation of its antinflammatory activity
    • Dia VP, Wang W, Oh VL, de Lumen BO, de Meja EG (2009). Isolation, purification and characterization of lunasin from defatted soybean flour and in vitro evaluation of its antinflammatory activity. Food Chem 114: 108–115.
    • (2009) Food Chem , vol.114 , pp. 108-115
    • Dia, V.P.1    Wang, W.2    Oh, V.L.3    de Lumen, B.O.4    de Meja, E.G.5
  • 39
    • 84884642795 scopus 로고    scopus 로고
    • Effect of probiotic fermented milk on blood pressure: a meta-analysis of randomised controlled trials
    • Dong JY, Szeto IM, Makinen K, Gao Q, Wang J, Qin LQ et al. (2013). Effect of probiotic fermented milk on blood pressure: a meta-analysis of randomised controlled trials. Br J Nutr 110: 1188–1194.
    • (2013) Br J Nutr , vol.110 , pp. 1188-1194
    • Dong, J.Y.1    Szeto, I.M.2    Makinen, K.3    Gao, Q.4    Wang, J.5    Qin, L.Q.6
  • 40
    • 33646572566 scopus 로고    scopus 로고
    • Immunomodulating capacity of commercial fish protein hydrolysate for diet supplementation
    • Duarte J, Vinderola G, Ritz B, Perdigon G, Matar C (2006). Immunomodulating capacity of commercial fish protein hydrolysate for diet supplementation. Immunobiology 211: 341–350.
    • (2006) Immunobiology , vol.211 , pp. 341-350
    • Duarte, J.1    Vinderola, G.2    Ritz, B.3    Perdigon, G.4    Matar, C.5
  • 43
    • 3042781436 scopus 로고    scopus 로고
    • Aplidine induces the mitochondrial apoptotic pathway via oxidative stress-mediated JNK and p38 activation and protein kinase C delta
    • García-Fernández LF, Losada A, Alcaide V, Alvarez AM, Cuadrado A, González L et al. (2002). Aplidine induces the mitochondrial apoptotic pathway via oxidative stress-mediated JNK and p38 activation and protein kinase C delta. Oncogene 21: 7533–7544.
    • (2002) Oncogene , vol.21 , pp. 7533-7544
    • García-Fernández, L.F.1    Losada, A.2    Alcaide, V.3    Alvarez, A.M.4    Cuadrado, A.5    González, L.6
  • 44
    • 84892638582 scopus 로고    scopus 로고
    • Antioxidant activity and protective effects of peptide lunasin against oxidative stress in intestinal Caco-2 cells
    • Garcia-Nebot MJ, Recio I, Hernandez-Ledesma B (2014). Antioxidant activity and protective effects of peptide lunasin against oxidative stress in intestinal Caco-2 cells. Food Chem Toxicol 65: 155–161.
    • (2014) Food Chem Toxicol , vol.65 , pp. 155-161
    • Garcia-Nebot, M.J.1    Recio, I.2    Hernandez-Ledesma, B.3
  • 45
    • 84901949675 scopus 로고    scopus 로고
    • Tumor homing peptides as molecular probes for cancer therapeutics, diagnostics and theranostics
    • Gautam A, Kapoor P, Chaudhary K, Kumar R, Raghava GP (2014). Tumor homing peptides as molecular probes for cancer therapeutics, diagnostics and theranostics. Curr Med Chem 21: 2367–2391.
    • (2014) Curr Med Chem , vol.21 , pp. 2367-2391
    • Gautam, A.1    Kapoor, P.2    Chaudhary, K.3    Kumar, R.4    Raghava, G.P.5
  • 46
    • 0030017920 scopus 로고    scopus 로고
    • Isolation of acid peptide fractions from a fish protein hydrolysate with strong stimulatory effect on Atlantic salmon (Salmo salar) head kidney leucocytes
    • Gildberg A, Bøgwald J, Johansen A, Stenberg E (1996). Isolation of acid peptide fractions from a fish protein hydrolysate with strong stimulatory effect on Atlantic salmon (Salmo salar) head kidney leucocytes. Comp Biochem Physiol B Biochem Mol Biol 114: 97–101.
    • (1996) Comp Biochem Physiol B Biochem Mol Biol , vol.114 , pp. 97-101
    • Gildberg, A.1    Bøgwald, J.2    Johansen, A.3    Stenberg, E.4
  • 47
    • 77956698814 scopus 로고    scopus 로고
    • Antioxidant activity of fish sauces including puffer (Lagocephalus wheeleri) fish sauce measured by the oxygen radical absorbance capacity method
    • Harada K, Maeda T, Hasegawa Y, Tokunaga T, Tamura Y, Koizumi T (2010). Antioxidant activity of fish sauces including puffer (Lagocephalus wheeleri) fish sauce measured by the oxygen radical absorbance capacity method. Mol Med Rep 3: 663–668.
    • (2010) Mol Med Rep , vol.3 , pp. 663-668
    • Harada, K.1    Maeda, T.2    Hasegawa, Y.3    Tokunaga, T.4    Tamura, Y.5    Koizumi, T.6
  • 48
    • 34147123803 scopus 로고    scopus 로고
    • Food-derived peptides with biological activity: from research to food applications
    • Hartmann R, Meisel H (2007). Food-derived peptides with biological activity: from research to food applications. Curr Opin Biotechnol 18: 163–169.
    • (2007) Curr Opin Biotechnol , vol.18 , pp. 163-169
    • Hartmann, R.1    Meisel, H.2
  • 49
    • 0032213421 scopus 로고    scopus 로고
    • Identification of a phosphopeptide in bovine alpha s1-casein digest as a factor influencing proliferation and immunoglobulin production in lymphocyte cultures
    • Hata I, Higashiyama S, Otani H (1998). Identification of a phosphopeptide in bovine alpha s1-casein digest as a factor influencing proliferation and immunoglobulin production in lymphocyte cultures. J Dairy Res 65: 569–578.
    • (1998) J Dairy Res , vol.65 , pp. 569-578
    • Hata, I.1    Higashiyama, S.2    Otani, H.3
  • 50
    • 0030605961 scopus 로고    scopus 로고
    • Antiproliferative and receptor binding properties of α- and β-casomorphins in the T47D human breast cancer cell line
    • Hatzoglou A, Bakogeorgou E, Hatzoglou CM, Martin P, Castanas E (1996). Antiproliferative and receptor binding properties of α- and β-casomorphins in the T47D human breast cancer cell line. Eur J Pharmacol 310: 217–223.
    • (1996) Eur J Pharmacol , vol.310 , pp. 217-223
    • Hatzoglou, A.1    Bakogeorgou, E.2    Hatzoglou, C.M.3    Martin, P.4    Castanas, E.5
  • 51
    • 85017430385 scopus 로고    scopus 로고
    • Chemopreventive role of food-derived proteins and peptides: a review
    • Hernandez-Ledesma B, Hsieh CC (2015). Chemopreventive role of food-derived proteins and peptides: a review. Crit Rev Food Sci Nutr. doi:10.1080/10408398.2015.1057632.
    • (2015) Crit Rev Food Sci Nutr
    • Hernandez-Ledesma, B.1    Hsieh, C.C.2
  • 52
    • 70449697863 scopus 로고    scopus 로고
    • Antioxidant and anti-inflammatory properties of cancer preventive peptide lunasin in RAW 264.7 macrophages
    • Hernandez-Ledesma B, Hsieh CC, de Lumen BO (2009). Antioxidant and anti-inflammatory properties of cancer preventive peptide lunasin in RAW 264.7 macrophages. Biochem Biophys Res Commun 390: 803–808.
    • (2009) Biochem Biophys Res Commun , vol.390 , pp. 803-808
    • Hernandez-Ledesma, B.1    Hsieh, C.C.2    de Lumen, B.O.3
  • 55
    • 0034081886 scopus 로고    scopus 로고
    • A possible new role for the anti-ageing peptide carnosine
    • Hipkiss AR, Brownson C (2000). A possible new role for the anti-ageing peptide carnosine. Cell Mol Life Sci 7: 747–753.
    • (2000) Cell Mol Life Sci , vol.7 , pp. 747-753
    • Hipkiss, A.R.1    Brownson, C.2
  • 56
    • 80054109587 scopus 로고    scopus 로고
    • Differential effects of dietary protein sources on postprandial low-grade inflammation after a single high fat meal in obese non-diabetic subjects
    • Holmer-Jensen J, Karhu T, Mortensen LS, Pedersen SB, Herzig KH, Hermansen K (2011). Differential effects of dietary protein sources on postprandial low-grade inflammation after a single high fat meal in obese non-diabetic subjects. Nutr J 10: 115.
    • (2011) Nutr J , vol.10 , pp. 115
    • Holmer-Jensen, J.1    Karhu, T.2    Mortensen, L.S.3    Pedersen, S.B.4    Herzig, K.H.5    Hermansen, K.6
  • 58
    • 84884277476 scopus 로고    scopus 로고
    • The role of nutrition, nutraceuticals, vitamins, antioxidants, and minerals in the prevention and treatment of hypertension
    • Houston MC (2013). The role of nutrition, nutraceuticals, vitamins, antioxidants, and minerals in the prevention and treatment of hypertension. Altern Ther Health Med 19 (Suppl. 1): 32–49.
    • (2013) Altern Ther Health Med , vol.19 , pp. 32-49
    • Houston, M.C.1
  • 59
    • 78149379509 scopus 로고    scopus 로고
    • Soybean peptide lunasin suppresses in vitro and in vivo 7,12-dimethylbenz[a]anthracene-induced tumorigenesis
    • Hsieh CC, Hernández-Ledesma B, de Lumen BO (2010). Soybean peptide lunasin suppresses in vitro and in vivo 7,12-dimethylbenz[a]anthracene-induced tumorigenesis. J Food Sci 75: H311–H316.
    • (2010) J Food Sci , vol.75 , pp. H311-H316
    • Hsieh, C.C.1    Hernández-Ledesma, B.2    de Lumen, B.O.3
  • 60
    • 78650679271 scopus 로고    scopus 로고
    • Antiproliferative activity of peptides prepared from enzymatic hydrolysates of tuna dark muscle on human breast cancer cell line MCF-7
    • Hsu KC, Li-Chan ECY, Jao CL (2011). Antiproliferative activity of peptides prepared from enzymatic hydrolysates of tuna dark muscle on human breast cancer cell line MCF-7. Food Chem 126: 617–622.
    • (2011) Food Chem , vol.126 , pp. 617-622
    • Hsu, K.C.1    Li-Chan, E.C.Y.2    Jao, C.L.3
  • 61
    • 84871784275 scopus 로고    scopus 로고
    • Antitumor effect of a polypeptide fraction from Arca subcrenata in vitro and in vivo
    • Hu X, Song L, Huang L, Zheng Q, Yu R (2012). Antitumor effect of a polypeptide fraction from Arca subcrenata in vitro and in vivo. Mar Drugs 10: 2782–2794.
    • (2012) Mar Drugs , vol.10 , pp. 2782-2794
    • Hu, X.1    Song, L.2    Huang, L.3    Zheng, Q.4    Yu, R.5
  • 62
    • 75449100518 scopus 로고    scopus 로고
    • Hydroxyproline-containing dipeptides and tripeptides quantified at high concentration in human blood after oral administration of gelatin hydrolysate
    • Ichikawa S, Morifuji M, Ohara H, Matsumoto H, Takeuchi Y, Sato K (2010). Hydroxyproline-containing dipeptides and tripeptides quantified at high concentration in human blood after oral administration of gelatin hydrolysate. Int J Food Sci Nutr 61: 52–60.
    • (2010) Int J Food Sci Nutr , vol.61 , pp. 52-60
    • Ichikawa, S.1    Morifuji, M.2    Ohara, H.3    Matsumoto, H.4    Takeuchi, Y.5    Sato, K.6
  • 63
    • 23844442461 scopus 로고    scopus 로고
    • Identification of food-derived collagen peptides in human blood after oral ingestion of gelatin hydrolysates
    • Iwai K, Hasegawa T, Taguchi Y, Morimatsu F, Sato K, Nakamura Y et al. (2005). Identification of food-derived collagen peptides in human blood after oral ingestion of gelatin hydrolysates. J Agric Food Chem 53: 6531–6536.
    • (2005) J Agric Food Chem , vol.53 , pp. 6531-6536
    • Iwai, K.1    Hasegawa, T.2    Taguchi, Y.3    Morimatsu, F.4    Sato, K.5    Nakamura, Y.6
  • 64
    • 35448968595 scopus 로고    scopus 로고
    • Antimicrobial and human cancer cell cytotoxic effect of synthetic angiotensin-converting enzyme (ACE) inhibitory peptides
    • Jang A, Jo C, Kang KS, Lee M (2008). Antimicrobial and human cancer cell cytotoxic effect of synthetic angiotensin-converting enzyme (ACE) inhibitory peptides. Food Chem 107: 327–336.
    • (2008) Food Chem , vol.107 , pp. 327-336
    • Jang, A.1    Jo, C.2    Kang, K.S.3    Lee, M.4
  • 65
    • 78249282622 scopus 로고    scopus 로고
    • Lunasin is prevalent in barley and is bioavailable and bioactive in in vivo and in vitro studies
    • Jeong HJ, Jeong JB, Hsieh CC, Hernàndez-Ledesma B, de Lumen BO (2010). Lunasin is prevalent in barley and is bioavailable and bioactive in in vivo and in vitro studies. Nutr Cancer 62: 1113–1119.
    • (2010) Nutr Cancer , vol.62 , pp. 1113-1119
    • Jeong, H.J.1    Jeong, J.B.2    Hsieh, C.C.3    Hernàndez-Ledesma, B.4    de Lumen, B.O.5
  • 66
    • 0037048768 scopus 로고    scopus 로고
    • Barley lunasin suppresses ras-induced colony formation and inhibits acetylation in mammalian cells
    • Jeong HJ, Lam Y, de Lumen BO (2002). Barley lunasin suppresses ras-induced colony formation and inhibits acetylation in mammalian cells. J Agric Food Chem 50: 5903–5908.
    • (2002) J Agric Food Chem , vol.50 , pp. 5903-5908
    • Jeong, H.J.1    Lam, Y.2    de Lumen, B.O.3
  • 67
    • 77955659706 scopus 로고    scopus 로고
    • Human cancer cell proliferation inhibition by a pentapeptide isolated and characterized from ricebran
    • Kannan A, Hettiarachchy NS, Lay JO, Liyanage R (2010). Human cancer cell proliferation inhibition by a pentapeptide isolated and characterized from ricebran. Peptides 31: 1629–1634.
    • (2010) Peptides , vol.31 , pp. 1629-1634
    • Kannan, A.1    Hettiarachchy, N.S.2    Lay, J.O.3    Liyanage, R.4
  • 68
    • 0038058742 scopus 로고    scopus 로고
    • Bioactive proteins and peptides from food sources. Applications of bioprocesses used in isolation and recovery
    • Kitts DD, Weiler K (2003). Bioactive proteins and peptides from food sources. Applications of bioprocesses used in isolation and recovery. Curr Pharm Des 9: 1309–1323.
    • (2003) Curr Pharm Des , vol.9 , pp. 1309-1323
    • Kitts, D.D.1    Weiler, K.2
  • 69
    • 0030041615 scopus 로고    scopus 로고
    • Antibacterial and immunostimulating casein-derived substances from milk: casecidin, isracidin peptides
    • Lahov E, Regelson W (1996). Antibacterial and immunostimulating casein-derived substances from milk: casecidin, isracidin peptides. Food Chem Toxicol 34: 131–145.
    • (1996) Food Chem Toxicol , vol.34 , pp. 131-145
    • Lahov, E.1    Regelson, W.2
  • 70
    • 84905566952 scopus 로고    scopus 로고
    • Lupin peptides lower low-density lipoprotein (LDL) cholesterol through an up-regulation of the LDL receptor/sterol regulatory element binding protein 2 (SREBP2) pathway at HepG2 cell line
    • Lammi C, Zanoni C, Scigliuolo GM, D'Amato A, Arnoldi A (2014). Lupin peptides lower low-density lipoprotein (LDL) cholesterol through an up-regulation of the LDL receptor/sterol regulatory element binding protein 2 (SREBP2) pathway at HepG2 cell line. J Agric Food Chem 62: 7151–7159.
    • (2014) J Agric Food Chem , vol.62 , pp. 7151-7159
    • Lammi, C.1    Zanoni, C.2    Scigliuolo, G.M.3    D'Amato, A.4    Arnoldi, A.5
  • 71
    • 84861201786 scopus 로고    scopus 로고
    • Effect of soy isoflavones on blood pressure: a meta-analysis of randomized controlled trials
    • Liu XX, Li SH, Chen JZ, Sun K, Wang XJ, Wang XG et al. (2012). Effect of soy isoflavones on blood pressure: a meta-analysis of randomized controlled trials. Nutr Metab Cardiovasc Dis 22: 463–470.
    • (2012) Nutr Metab Cardiovasc Dis , vol.22 , pp. 463-470
    • Liu, X.X.1    Li, S.H.2    Chen, J.Z.3    Sun, K.4    Wang, X.J.5    Wang, X.G.6
  • 72
    • 84925343564 scopus 로고    scopus 로고
    • Potential health benefits of lunasin: a multifaceted soy-derived bioactive peptide
    • Lule VK, Garg S, Pophaly SD, Hitesh, Tomar SK (2015). Potential health benefits of lunasin: a multifaceted soy-derived bioactive peptide. J Food Sci 80: R485–R494.
    • (2015) J Food Sci , vol.80 , pp. R485-R494
    • Lule, V.K.1    Garg, S.2    Pophaly, S.D.3    Hitesh4    Tomar, S.K.5
  • 73
    • 84873175341 scopus 로고    scopus 로고
    • Isolation and purification of a peptide from Bullacta exarata and its impaction of apoptosis on prostate cancer cell
    • Ma J, Huang F, Lin H, Wang X (2013). Isolation and purification of a peptide from Bullacta exarata and its impaction of apoptosis on prostate cancer cell. Mar Drugs 11: 266–273.
    • (2013) Mar Drugs , vol.11 , pp. 266-273
    • Ma, J.1    Huang, F.2    Lin, H.3    Wang, X.4
  • 74
    • 64849084974 scopus 로고    scopus 로고
    • Active Chinese mistletoe lectin-55 enhances colon cancer surveillance through regulating innate and adaptive immune responses
    • Ma YH, Cheng WZ, Gong F, Ma AL, Yu QW, Zhang JY et al. (2008). Active Chinese mistletoe lectin-55 enhances colon cancer surveillance through regulating innate and adaptive immune responses. World J Gastroenterol 14: 5274–5281.
    • (2008) World J Gastroenterol , vol.14 , pp. 5274-5281
    • Ma, Y.H.1    Cheng, W.Z.2    Gong, F.3    Ma, A.L.4    Yu, Q.W.5    Zhang, J.Y.6
  • 75
    • 33746842648 scopus 로고    scopus 로고
    • Cationic antimicrobial peptides as novel cytotoxic agents for cancer treatment
    • Mader JS, Hoskin DW (2006). Cationic antimicrobial peptides as novel cytotoxic agents for cancer treatment. Expert Opin Investig Drugs 15: 933–946.
    • (2006) Expert Opin Investig Drugs , vol.15 , pp. 933-946
    • Mader, J.S.1    Hoskin, D.W.2
  • 76
    • 84896691651 scopus 로고    scopus 로고
    • Egg-derived tri-peptide IRW exerts antihypertensive effects in spontaneously hypertensive rats
    • Majumder K, Chakrabarti S, Morton JS, Panahi S, Kaufman S, Davidge ST et al. (2013). Egg-derived tri-peptide IRW exerts antihypertensive effects in spontaneously hypertensive rats. PLoS One 8: e82829.
    • (2013) PLoS One , vol.8
    • Majumder, K.1    Chakrabarti, S.2    Morton, J.S.3    Panahi, S.4    Kaufman, S.5    Davidge, S.T.6
  • 77
    • 84959449385 scopus 로고    scopus 로고
    • The potential of food protein-derived anti-inflammatory peptides against various chronic inflammatory diseases
    • Majumder K, Mine Y, Wu J (2016). The potential of food protein-derived anti-inflammatory peptides against various chronic inflammatory diseases. J Sci Food Agric 96: 2303–2311.
    • (2016) J Sci Food Agric , vol.96 , pp. 2303-2311
    • Majumder, K.1    Mine, Y.2    Wu, J.3
  • 78
    • 84910123375 scopus 로고    scopus 로고
    • Bioactive peptides in cereals and legumes: agronomical, biochemical and clinical aspects
    • Malaguti M, Dinelli G, Leoncini E, Bregola V, Bosi S, Cicero AF et al. (2014). Bioactive peptides in cereals and legumes: agronomical, biochemical and clinical aspects. Int J Mol Sci 15: 21120–21135.
    • (2014) Int J Mol Sci , vol.15 , pp. 21120-21135
    • Malaguti, M.1    Dinelli, G.2    Leoncini, E.3    Bregola, V.4    Bosi, S.5    Cicero, A.F.6
  • 79
  • 80
    • 0035876208 scopus 로고    scopus 로고
    • Effects of Bowman-Birk inhibitorconcentrate (BBIC) in patients with benign prostatic hyperplasia
    • Malkowicz SB, McKenna WG, Vaughn DJ, Wan XS, Propert KJ, Rockwell K et al. (2001). Effects of Bowman-Birk inhibitorconcentrate (BBIC) in patients with benign prostatic hyperplasia. Prostate 48: 16–28.
    • (2001) Prostate , vol.48 , pp. 16-28
    • Malkowicz, S.B.1    McKenna, W.G.2    Vaughn, D.J.3    Wan, X.S.4    Propert, K.J.5    Rockwell, K.6
  • 81
    • 84977514840 scopus 로고    scopus 로고
    • Milk-derived bioactive peptides and their health promoting effects: a potential role in atherosclerosis
    • Marcone S, Belton O, Fitzgerald DJ (2016). Milk-derived bioactive peptides and their health promoting effects: a potential role in atherosclerosis. Br J Clin Pharmacol. doi:10.1111/bcp.13002.
    • (2016) Br J Clin Pharmacol
    • Marcone, S.1    Belton, O.2    Fitzgerald, D.J.3
  • 83
    • 83355175422 scopus 로고    scopus 로고
    • Soy protein supports cardiovascular health by downregulating hydroxymethylglutaryl-coenzyme A reductase and sterol regulatory element-binding protein-2 and increasing antioxidant enzyme activity in rats with dextran sodium sulfate-induced mild systemic inflammation
    • Marsh TG, Straub RK, Villalobos F, Hong MY (2011). Soy protein supports cardiovascular health by downregulating hydroxymethylglutaryl-coenzyme A reductase and sterol regulatory element-binding protein-2 and increasing antioxidant enzyme activity in rats with dextran sodium sulfate-induced mild systemic inflammation. Nutr Res 31: 922–928.
    • (2011) Nutr Res , vol.31 , pp. 922-928
    • Marsh, T.G.1    Straub, R.K.2    Villalobos, F.3    Hong, M.Y.4
  • 84
    • 0242467926 scopus 로고    scopus 로고
    • Isolation and characterization of angiotensin I-converting enzyme inhibitory peptides from wheat gliadin hydrolysate
    • Motoi H, Kodama T (2003). Isolation and characterization of angiotensin I-converting enzyme inhibitory peptides from wheat gliadin hydrolysate. Nahrung 47: 354–358.
    • (2003) Nahrung , vol.47 , pp. 354-358
    • Motoi, H.1    Kodama, T.2
  • 85
    • 84938282126 scopus 로고    scopus 로고
    • A review of extraction and analysis of bioactives in oat and barley and scope for use of novel food processing technologies
    • Nirupama G, Mohammad B, Hossain DKR, Nigel PB (2015). A review of extraction and analysis of bioactives in oat and barley and scope for use of novel food processing technologies. Molecules 20: 10884–10909.
    • (2015) Molecules , vol.20 , pp. 10884-10909
    • Nirupama, G.1    Mohammad, B.2    Hossain, D.K.R.3    Nigel, P.B.4
  • 86
    • 84940380637 scopus 로고    scopus 로고
    • Bioactive properties of milk proteins in humans: a review
    • Nongonierma AB, FitzGerald RJ (2015). Bioactive properties of milk proteins in humans: a review. Peptides 73: 20–34.
    • (2015) Peptides , vol.73 , pp. 20-34
    • Nongonierma, A.B.1    FitzGerald, R.J.2
  • 87
    • 3342928851 scopus 로고    scopus 로고
    • The antimicrobial activity of lactoferrin: current status and perspectives
    • Orsi N (2004). The antimicrobial activity of lactoferrin: current status and perspectives. Biometals 17: 189–196.
    • (2004) Biometals , vol.17 , pp. 189-196
    • Orsi, N.1
  • 88
    • 84934444542 scopus 로고    scopus 로고
    • Peptide-based drug design: here and now
    • Otvos L Jr (2008). Peptide-based drug design: here and now. Methods Mol Biol 494: 1–8.
    • (2008) Methods Mol Biol , vol.494 , pp. 1-8
    • Otvos, L.1
  • 89
    • 27144441748 scopus 로고    scopus 로고
    • Contents and bioactivities of lunasin, bowman-birk inhibitor, and isoflavones in soybean seed
    • Park JH, Jeong HJ, de Lumen BO (2005a). Contents and bioactivities of lunasin, bowman-birk inhibitor, and isoflavones in soybean seed. J Agric Food Chem 53: 7686–7690.
    • (2005) J Agric Food Chem , vol.53 , pp. 7686-7690
    • Park, J.H.1    Jeong, H.J.2    de Lumen, B.O.3
  • 90
    • 33644631847 scopus 로고    scopus 로고
    • Isolation and identification of peptides from soy 11S-globulin with hypocholesterolemic activity
    • Park VV, Koo MS, Kasymova TD, Kwon DY (2005b). Isolation and identification of peptides from soy 11S-globulin with hypocholesterolemic activity. Chem Nat Comp 41: 710–714.
    • (2005) Chem Nat Comp , vol.41 , pp. 710-714
    • Park, V.V.1    Koo, M.S.2    Kasymova, T.D.3    Kwon, D.Y.4
  • 91
    • 84862320290 scopus 로고    scopus 로고
    • Casein phosphopeptides modulate proliferation and apoptosis in HT-29 cell line through their interaction with voltage-operated L-type calcium channels
    • Perego S, Cosentino S, Fiorilli A, Tettamanti G, Ferraretto A (2012). Casein phosphopeptides modulate proliferation and apoptosis in HT-29 cell line through their interaction with voltage-operated L-type calcium channels. J Nutr Biochem 23: 808–816.
    • (2012) J Nutr Biochem , vol.23 , pp. 808-816
    • Perego, S.1    Cosentino, S.2    Fiorilli, A.3    Tettamanti, G.4    Ferraretto, A.5
  • 92
    • 33748319573 scopus 로고    scopus 로고
    • Antioxidative peptides derived from milk proteins
    • Pihlanto A (2006). Antioxidative peptides derived from milk proteins. Int Dairy J 16: 1306–1314.
    • (2006) Int Dairy J , vol.16 , pp. 1306-1314
    • Pihlanto, A.1
  • 93
    • 0034633086 scopus 로고    scopus 로고
    • Bioactive peptides derived from bovine whey proteins: opioid and ace-inhibitory peptides
    • Pihlanto-Leppälä A (2000). Bioactive peptides derived from bovine whey proteins: opioid and ace-inhibitory peptides. Trends Food Sci Technol 11: 347–356.
    • (2000) Trends Food Sci Technol , vol.11 , pp. 347-356
    • Pihlanto-Leppälä, A.1
  • 94
    • 77951270043 scopus 로고    scopus 로고
    • Amino acid composition and antioxidant properties of pea seed (Pisum sativumL.) enzymatic protein hydrolysate fractions
    • Pownall TL, Udenigwe CC, Aluko RE (2010). Amino acid composition and antioxidant properties of pea seed (Pisum sativumL.) enzymatic protein hydrolysate fractions. J Agric Food Chem 58: 4712–4718.
    • (2010) J Agric Food Chem , vol.58 , pp. 4712-4718
    • Pownall, T.L.1    Udenigwe, C.C.2    Aluko, R.E.3
  • 95
    • 84928492349 scopus 로고    scopus 로고
    • Antihypertensive Peptides from Food Proteins
    • Rotimi EA (2015). Antihypertensive Peptides from Food Proteins. Annu Rev Food Sci Technol 6: 235–262.
    • (2015) Annu Rev Food Sci Technol , vol.6 , pp. 235-262
    • Rotimi, E.A.1
  • 96
    • 84868123294 scopus 로고    scopus 로고
    • Food proteins as a source of bioactive peptides with diverse functions
    • Rutherfurd-Markwick KJ (2012). Food proteins as a source of bioactive peptides with diverse functions. Br J Nutr 108 (Suppl. 2): S149–S157.
    • (2012) Br J Nutr , vol.108 , pp. S149-S157
    • Rutherfurd-Markwick, K.J.1
  • 97
    • 34347344821 scopus 로고    scopus 로고
    • Negative growth control of osteosarcoma cell by Bowman-Birk protease inhibitor from soybean; involvement of connexin 43
    • Saito T, Sato H, Virgona N, Hagiwara H, Kashiwagi K, Suzuki K et al. (2007). Negative growth control of osteosarcoma cell by Bowman-Birk protease inhibitor from soybean; involvement of connexin 43. Cancer Lett 253: 249–257.
    • (2007) Cancer Lett , vol.253 , pp. 249-257
    • Saito, T.1    Sato, H.2    Virgona, N.3    Hagiwara, H.4    Kashiwagi, K.5    Suzuki, K.6
  • 98
    • 84879754818 scopus 로고    scopus 로고
    • Identification of a hepatoprotective peptide in wheat gluten hydrolysate against D-galactosamine-induced acute hepatitis in rats
    • Sato K, Egashira Y, Ono S, Mochizuki S, Shimmura Y, Suzuki Y et al. (2013). Identification of a hepatoprotective peptide in wheat gluten hydrolysate against D-galactosamine-induced acute hepatitis in rats. J Agric Food Chem 61: 6304–6310.
    • (2013) J Agric Food Chem , vol.61 , pp. 6304-6310
    • Sato, K.1    Egashira, Y.2    Ono, S.3    Mochizuki, S.4    Shimmura, Y.5    Suzuki, Y.6
  • 99
    • 0024351114 scopus 로고
    • Reduction of B16 melanoma metastases by oral administration of egg-whitelysozyme
    • Sava G (1989). Reduction of B16 melanoma metastases by oral administration of egg-whitelysozyme. Cancer Chemother Pharmacol 25: 221–222.
    • (1989) Cancer Chemother Pharmacol , vol.25 , pp. 221-222
    • Sava, G.1
  • 100
    • 0029622438 scopus 로고
    • Lysozyme stimulates lymphocyte response to ConA and IL-2 and potentiates 5-fluorouracil action on advanced carcinomas
    • Sava G, Pacor S, Dasic G, Bergamo A (1995). Lysozyme stimulates lymphocyte response to ConA and IL-2 and potentiates 5-fluorouracil action on advanced carcinomas. Anticancer Res 15: 1883–1888.
    • (1995) Anticancer Res , vol.15 , pp. 1883-1888
    • Sava, G.1    Pacor, S.2    Dasic, G.3    Bergamo, A.4
  • 101
    • 71749100398 scopus 로고    scopus 로고
    • Cationic amphiphilic peptides with cancer-selective toxicity
    • Schweizer F (2009). Cationic amphiphilic peptides with cancer-selective toxicity. Eur J Pharmacol 625: 190–194.
    • (2009) Eur J Pharmacol , vol.625 , pp. 190-194
    • Schweizer, F.1
  • 102
    • 43049176801 scopus 로고    scopus 로고
    • Molecular mechanisms of mistletoe plant extract-induced apoptosis in acute lymphoblastic leukemia in vivo and in vitro
    • Seifert G, Jesse P, Laengler A, Reindl T, Lüth M, Lobitz S et al. (2008). Molecular mechanisms of mistletoe plant extract-induced apoptosis in acute lymphoblastic leukemia in vivo and in vitro. Cancer Lett 264: 218–228.
    • (2008) Cancer Lett , vol.264 , pp. 218-228
    • Seifert, G.1    Jesse, P.2    Laengler, A.3    Reindl, T.4    Lüth, M.5    Lobitz, S.6
  • 103
    • 59849104535 scopus 로고    scopus 로고
    • Effect of prolyl-hydroxyproline (Pro–Hyp), a food-derived collagen peptide in human blood, on growth of fibroblasts from mouse skin
    • Shigemura Y, Iwai K, Morimatsu F, Iwamoto T, Mori T, Oda C et al. (2009). Effect of prolyl-hydroxyproline (Pro–Hyp), a food-derived collagen peptide in human blood, on growth of fibroblasts from mouse skin. J Agric Food Chem 57: 444–449.
    • (2009) J Agric Food Chem , vol.57 , pp. 444-449
    • Shigemura, Y.1    Iwai, K.2    Morimatsu, F.3    Iwamoto, T.4    Mori, T.5    Oda, C.6
  • 105
    • 84942988778 scopus 로고    scopus 로고
    • Nutraceuticals for blood pressure control
    • Sirtori CR, Arnoldi A, Cicero AF (2015). Nutraceuticals for blood pressure control. Ann Med 47: 447–456.
    • (2015) Ann Med , vol.47 , pp. 447-456
    • Sirtori, C.R.1    Arnoldi, A.2    Cicero, A.F.3
  • 106
    • 84863798036 scopus 로고    scopus 로고
    • Hypocholesterolaemic effects of lupin protein and pea protein/fibre combinations in moderately hypercholesterolaemic individuals
    • Sirtori CR, Triolo M, Bosisio R, Bondioli A, Calabresi L, De Vergori V et al. (2012). Hypocholesterolaemic effects of lupin protein and pea protein/fibre combinations in moderately hypercholesterolaemic individuals. Br J Nutr 107: 1176–1183.
    • (2012) Br J Nutr , vol.107 , pp. 1176-1183
    • Sirtori, C.R.1    Triolo, M.2    Bosisio, R.3    Bondioli, A.4    Calabresi, L.5    De Vergori, V.6
  • 107
    • 84976865494 scopus 로고    scopus 로고
    • The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands
    • Southan C, Sharman JL, Benson HE, Faccenda E, Pawson AJ, Alexander SP et al. (2016). The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. Nucl Acids Res 44: D1054–D1068.
    • (2016) Nucl Acids Res , vol.44 , pp. D1054-D1068
    • Southan, C.1    Sharman, J.L.2    Benson, H.E.3    Faccenda, E.4    Pawson, A.J.5    Alexander, S.P.6
  • 108
    • 84899959826 scopus 로고    scopus 로고
    • Effects of an anticarcinogenic Bowman-Birk protease inhibitor on purified 20S proteasome and MCF-7 breast cancer cells
    • Souza Lda C, Camargo R, Demasi M, Santana JM, de Sá CM, de Freitas SM (2014). Effects of an anticarcinogenic Bowman-Birk protease inhibitor on purified 20S proteasome and MCF-7 breast cancer cells. PLoS One 9: e86600.
    • (2014) PLoS One , vol.9
    • Souza Lda, C.1    Camargo, R.2    Demasi, M.3    Santana, J.M.4    de Sá, C.M.5    de Freitas, S.M.6
  • 109
    • 84870666521 scopus 로고    scopus 로고
    • Iron-saturated bovine lactoferrin improves the chemotherapeutic effects of tamoxifen in the treatment of basal-like breast cancer in mice
    • Sun X, Jiang R, Przepiorski A, Reddy S, Palmano KP, Krissansen GW (2012). Iron-saturated bovine lactoferrin improves the chemotherapeutic effects of tamoxifen in the treatment of basal-like breast cancer in mice. BMC Cancer 12: 591.
    • (2012) BMC Cancer , vol.12 , pp. 591
    • Sun, X.1    Jiang, R.2    Przepiorski, A.3    Reddy, S.4    Palmano, K.P.5    Krissansen, G.W.6
  • 110
    • 24744463417 scopus 로고    scopus 로고
    • Restoration of connexin 43 by Bowman-Birk protease inhibitor in M5076 bearing mice
    • Suzuki K, Yano T, Sadzuka Y, Sugiyama T, Seki T, Asano R (2005). Restoration of connexin 43 by Bowman-Birk protease inhibitor in M5076 bearing mice. Oncol Rep 13: 1247–1250.
    • (2005) Oncol Rep , vol.13 , pp. 1247-1250
    • Suzuki, K.1    Yano, T.2    Sadzuka, Y.3    Sugiyama, T.4    Seki, T.5    Asano, R.6
  • 111
    • 0038396397 scopus 로고    scopus 로고
    • Opioid receptor ligands derived from food proteins
    • Teschemacher H (2003). Opioid receptor ligands derived from food proteins. Curr Pharm Des 9: 1331–1344.
    • (2003) Curr Pharm Des , vol.9 , pp. 1331-1344
    • Teschemacher, H.1
  • 112
    • 84885390747 scopus 로고    scopus 로고
    • Cancer treatment using peptides: current therapies and future prospects
    • Thundimadathil J (2012). Cancer treatment using peptides: current therapies and future prospects. J Amino Acids 2012: 967347.
    • (2012) J Amino Acids , vol.2012 , pp. 967347
    • Thundimadathil, J.1
  • 113
    • 84894934931 scopus 로고    scopus 로고
    • The mechanisms by which pardaxin, a natural cationic antimicrobial peptide, targets the endoplasmic reticulum and induces c-FOS
    • Ting CH, Huang HN, Huang TC, Wu CJ, Chen JY (2014). The mechanisms by which pardaxin, a natural cationic antimicrobial peptide, targets the endoplasmic reticulum and induces c-FOS. Biomaterials 35: 3627–3640.
    • (2014) Biomaterials , vol.35 , pp. 3627-3640
    • Ting, C.H.1    Huang, H.N.2    Huang, T.C.3    Wu, C.J.4    Chen, J.Y.5
  • 114
    • 84941022986 scopus 로고    scopus 로고
    • Soya products and serum lipids: a meta-analysis of randomised controlled trials
    • Tokede OA, Onabanjo TA, Yansane A, Gaziano JM, Djoussé L (2015). Soya products and serum lipids: a meta-analysis of randomised controlled trials. Br J Nutr 114: 831–843.
    • (2015) Br J Nutr , vol.114 , pp. 831-843
    • Tokede, O.A.1    Onabanjo, T.A.2    Yansane, A.3    Gaziano, J.M.4    Djoussé, L.5
  • 116
    • 84856032752 scopus 로고    scopus 로고
    • Food protein-derived bioactive peptides: production, processing, and potential health benefits
    • Udenigwe CC, Aluko RE (2012). Food protein-derived bioactive peptides: production, processing, and potential health benefits. J Food Sci 77: R11–R24.
    • (2012) J Food Sci , vol.77 , pp. R11-R24
    • Udenigwe, C.C.1    Aluko, R.E.2
  • 118
    • 3242882447 scopus 로고    scopus 로고
    • Oral lactoferrin inhibits growth of established tumors and potentiates conventional chemotherapy
    • Varadhachary A, Wolf JS, Petrak K, O'Malley BW Jr, Spadaro M, Curcio C et al. (2004). Oral lactoferrin inhibits growth of established tumors and potentiates conventional chemotherapy. Int J Cancer 111: 398–403.
    • (2004) Int J Cancer , vol.111 , pp. 398-403
    • Varadhachary, A.1    Wolf, J.S.2    Petrak, K.3    O'Malley, B.W.4    Spadaro, M.5    Curcio, C.6
  • 120
    • 33947319293 scopus 로고    scopus 로고
    • Antioxidant properties of papain hydrolysates of wheat gluten in different oxidation systems
    • Wang J, Zhao M, Zhao Q, Jiang Y (2007). Antioxidant properties of papain hydrolysates of wheat gluten in different oxidation systems. Food Chem 101: 1658–1663.
    • (2007) Food Chem , vol.101 , pp. 1658-1663
    • Wang, J.1    Zhao, M.2    Zhao, Q.3    Jiang, Y.4
  • 121
    • 77649230546 scopus 로고    scopus 로고
    • Oyster (Crassostrea gigas) hydrolysates produced on a plant scale have antitumor activity and immunostimulating effects in BALB/c mice
    • Wang YK, He HL, Wang GF, Wu H, Zhou BC, Chen XL et al. (2010). Oyster (Crassostrea gigas) hydrolysates produced on a plant scale have antitumor activity and immunostimulating effects in BALB/c mice. Mar Drugs 8: 255–268.
    • (2010) Mar Drugs , vol.8 , pp. 255-268
    • Wang, Y.K.1    He, H.L.2    Wang, G.F.3    Wu, H.4    Zhou, B.C.5    Chen, X.L.6
  • 122
    • 0001255351 scopus 로고    scopus 로고
    • Antitumor effects of pronase-treated fragments, glycopeptides, from ovomucin in hen egg white in a double grafted tumor system
    • Watanabe K, Tsuge Y, Shimoyamada M, Ogama N, Ebina T (1998). Antitumor effects of pronase-treated fragments, glycopeptides, from ovomucin in hen egg white in a double grafted tumor system. J Agric Food Chem 46: 3033–3038.
    • (1998) J Agric Food Chem , vol.46 , pp. 3033-3038
    • Watanabe, K.1    Tsuge, Y.2    Shimoyamada, M.3    Ogama, N.4    Ebina, T.5
  • 123
    • 84939124523 scopus 로고    scopus 로고
    • Cheese whey: A potential resource to transform into bioprotein, functional/nutritional proteins and bioactive peptides
    • Yadav JS, Yan S, Pilli S, Kumar L, Tyagi RD, Surampalli RY (2015). Cheese whey: A potential resource to transform into bioprotein, functional/nutritional proteins and bioactive peptides. Biotechnol Adv 33 (6 Pt 1): 756–774.
    • (2015) Biotechnol Adv , vol.33 , Issue.6 , pp. 756-774
    • Yadav, J.S.1    Yan, S.2    Pilli, S.3    Kumar, L.4    Tyagi, R.D.5    Surampalli, R.Y.6
  • 124
    • 0842309109 scopus 로고    scopus 로고
    • Beta-lactotensin and neurotensin rapidly reduce serum cholesterol via NT2 receptor
    • Yamauchi R, Ohinata K, Yoshikawa M (2003). Beta-lactotensin and neurotensin rapidly reduce serum cholesterol via NT2 receptor. Peptides 24: 1955–1961.
    • (2003) Peptides , vol.24 , pp. 1955-1961
    • Yamauchi, R.1    Ohinata, K.2    Yoshikawa, M.3
  • 125
    • 53949124119 scopus 로고    scopus 로고
    • Immunomodulatory effects of marine oligopeptide preparation from chum salmon (Oncorhynchus keta) in mice
    • Yang Y, Zhang Z, Pei X, Han H, Wang J, Wang L et al. (2009). Immunomodulatory effects of marine oligopeptide preparation from chum salmon (Oncorhynchus keta) in mice. Food Chem 113: 464–470.
    • (2009) Food Chem , vol.113 , pp. 464-470
    • Yang, Y.1    Zhang, Z.2    Pei, X.3    Han, H.4    Wang, J.5    Wang, L.6
  • 126
    • 0030940982 scopus 로고    scopus 로고
    • Bovine lactoferrin and lactoferricin, a peptide derived from bovine lactoferrin, inhibit tumor metastasis in mice
    • Yoo YC, Watanabe S, Watanabe R, Hata K, Shimazaki K, Azuma I (1997). Bovine lactoferrin and lactoferricin, a peptide derived from bovine lactoferrin, inhibit tumor metastasis in mice. Jpn J Cancer Res 88: 184–190.
    • (1997) Jpn J Cancer Res , vol.88 , pp. 184-190
    • Yoo, Y.C.1    Watanabe, S.2    Watanabe, R.3    Hata, K.4    Shimazaki, K.5    Azuma, I.6
  • 127
    • 84946564598 scopus 로고    scopus 로고
    • Bioactive peptides derived from natural proteins with respect to diversity of their receptors and physiological effects
    • Yoshikawa M (2015). Bioactive peptides derived from natural proteins with respect to diversity of their receptors and physiological effects. Peptides 72: 208–225.
    • (2015) Peptides , vol.72 , pp. 208-225
    • Yoshikawa, M.1
  • 128
    • 84873925016 scopus 로고    scopus 로고
    • Prevention of cardiovascular disease guided by total risk estimations--challenges and opportunities for practical implementation: highlights of a cardiovascular clinical trialists (CVCT) workshop of the ESC working group on cardiovascular pharmacology and drug therapy. ESC working group on cardiovascular pharmacology and drug therapy
    • Zannad F, Dallongeville J, Macfadyen RJ, Ruilope LM, Wilhelmsen L, De Backer G et al. (2012). Prevention of cardiovascular disease guided by total risk estimations--challenges and opportunities for practical implementation: highlights of a cardiovascular clinical trialists (CVCT) workshop of the ESC working group on cardiovascular pharmacology and drug therapy. ESC working group on cardiovascular pharmacology and drug therapy. Eur J Prev Cardiol 19: 1454–1464.
    • (2012) Eur J Prev Cardiol , vol.19 , pp. 1454-1464
    • Zannad, F.1    Dallongeville, J.2    Macfadyen, R.J.3    Ruilope, L.M.4    Wilhelmsen, L.5    De Backer, G.6
  • 129
    • 84920146075 scopus 로고    scopus 로고
    • Reniochalistatins A-E, cyclic peptides from the marine sponge Reniochalina stalagmitis
    • Zhan KX, Jiao WH, Yang F, Li J, Wang SP, Li YS et al. (2014). Reniochalistatins A-E, cyclic peptides from the marine sponge Reniochalina stalagmitis. J Nat Prod 77: 2678–2684.
    • (2014) J Nat Prod , vol.77 , pp. 2678-2684
    • Zhan, K.X.1    Jiao, W.H.2    Yang, F.3    Li, J.4    Wang, S.P.5    Li, Y.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.