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Volumn 6, Issue 11, 2015, Pages

Role of necroptosis in the pathogenesis of solid organ injury

Author keywords

[No Author keywords available]

Indexed keywords

MLKL INHIBITOR; NECROSTATIN 1; PROTEIN; PROTEIN DERIVATIVE; PROTEIN INHIBITOR; RIP 1 INHIBITOR; RIPK3 INHIBITOR; UNCLASSIFIED DRUG;

EID: 84989911652     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2015.316     Document Type: Review
Times cited : (113)

References (112)
  • 3
    • 84897088275 scopus 로고    scopus 로고
    • Activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis
    • Newton K, Dugger DL, Wickliffe KE, Kapoor N, de Almagro MC, Vucic D et al. Activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis. Science 2014; 343: 1357-1360.
    • (2014) Science , vol.343 , pp. 1357-1360
    • Newton, K.1    Dugger, D.L.2    Wickliffe, K.E.3    Kapoor, N.4    De Almagro, M.C.5    Vucic, D.6
  • 4
    • 84862907788 scopus 로고    scopus 로고
    • Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase
    • Sun L, Wang H, Wang Z, He S, Chen S, Liao D et al. Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase. Cell 2012; 148: 213-227.
    • (2012) Cell , vol.148 , pp. 213-227
    • Sun, L.1    Wang, H.2    Wang, Z.3    He, S.4    Chen, S.5    Liao, D.6
  • 5
    • 84904322380 scopus 로고    scopus 로고
    • RIP3, a kinase promoting necroptotic cell death, mediates adverse remodelling after myocardial infarction
    • Luedde M, Lutz M, Carter N, Sosna J, Jacoby C, Vucur M et al. RIP3, a kinase promoting necroptotic cell death, mediates adverse remodelling after myocardial infarction. Cardiovasc Res 2014; 103: 206-216.
    • (2014) Cardiovasc Res , vol.103 , pp. 206-216
    • Luedde, M.1    Lutz, M.2    Carter, N.3    Sosna, J.4    Jacoby, C.5    Vucur, M.6
  • 6
    • 50249132439 scopus 로고    scopus 로고
    • Necrostatin-1 reduces histopathology and improves functional outcome after controlled cortical impact in mice
    • You Z, Savitz SI, Yang J, Degterev A, Yuan J, Cuny GD et al. Necrostatin-1 reduces histopathology and improves functional outcome after controlled cortical impact in mice. J Cereb Blood Flow Metab 2008; 28: 1564-1573.
    • (2008) J Cereb Blood Flow Metab , vol.28 , pp. 1564-1573
    • You, Z.1    Savitz, S.I.2    Yang, J.3    Degterev, A.4    Yuan, J.5    Cuny, G.D.6
  • 8
    • 84904562812 scopus 로고    scopus 로고
    • RIPK3-mediated necroptosis regulates cardiac allograft rejection
    • Pavlosky A, Lau A, Su Y, Lian D, Huang X, Yin Z et al. RIPK3-mediated necroptosis regulates cardiac allograft rejection. Am J Transplant 2014; 14: 1778-1790.
    • (2014) Am J Transplant , vol.14 , pp. 1778-1790
    • Pavlosky, A.1    Lau, A.2    Su, Y.3    Lian, D.4    Huang, X.5    Yin, Z.6
  • 9
    • 84886796430 scopus 로고    scopus 로고
    • RIPK3-mediated necroptosis promotes donor kidney inflammatory injury and reduces allograft survival
    • Lau A, Wang S, Jiang J, Haig A, Pavlosky A, Linkermann A et al. RIPK3-mediated necroptosis promotes donor kidney inflammatory injury and reduces allograft survival. Am J Transplant 2013; 13: 2805-2818.
    • (2013) Am J Transplant , vol.13 , pp. 2805-2818
    • Lau, A.1    Wang, S.2    Jiang, J.3    Haig, A.4    Pavlosky, A.5    Linkermann, A.6
  • 10
    • 67650638892 scopus 로고    scopus 로고
    • RIP kinases at the crossroads of cell death and survival
    • Declercq W, Vanden Berghe T, Vandenabeele P. RIP kinases at the crossroads of cell death and survival. Cell 2009; 138: 229-232.
    • (2009) Cell , vol.138 , pp. 229-232
    • Declercq, W.1    Vanden Berghe, T.2    Vandenabeele, P.3
  • 11
    • 0036781052 scopus 로고    scopus 로고
    • NF-kappaB regulation in the immune system
    • Li Q, Verma IM. NF-kappaB regulation in the immune system. Nat Rev Immunol 2002; 2: 725-734.
    • (2002) Nat Rev Immunol , vol.2 , pp. 725-734
    • Li, Q.1    Verma, I.M.2
  • 13
    • 79952623655 scopus 로고    scopus 로고
    • CIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3- dependent reactive oxygen species production
    • Vanlangenakker N, Vanden Berghe T, Bogaert P, Laukens B, Zobel K, Deshayes K et al. cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3- dependent reactive oxygen species production. Cell Death Differ 2011; 18: 656-665.
    • (2011) Cell Death Differ , vol.18 , pp. 656-665
    • Vanlangenakker, N.1    Vanden Berghe, T.2    Bogaert, P.3    Laukens, B.4    Zobel, K.5    Deshayes, K.6
  • 14
    • 57649181391 scopus 로고    scopus 로고
    • Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway
    • Hitomi J, Christofferson DE, Ng A, Yao J, Degterev A, Xavier RJ et al. Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway. Cell 2008; 135: 1311-1323.
    • (2008) Cell , vol.135 , pp. 1311-1323
    • Hitomi, J.1    Christofferson, D.E.2    Ng, A.3    Yao, J.4    Degterev, A.5    Xavier, R.J.6
  • 15
    • 84884823502 scopus 로고    scopus 로고
    • CYLD deubiquitinates RIP1 in the TNFalpha-induced necrosome to facilitate kinase activation and programmed necrosis
    • Moquin DM, McQuade T, Chan FK. CYLD deubiquitinates RIP1 in the TNFalpha-induced necrosome to facilitate kinase activation and programmed necrosis. PLoS One 2013; 8: E76841.
    • (2013) PLoS One , vol.8 , pp. e76841
    • Moquin, D.M.1    McQuade, T.2    Chan, F.K.3
  • 16
    • 84989885436 scopus 로고    scopus 로고
    • Cellular IAP proteins and LUBAC differentially regulate necrosome-associated RIP1 ubiquitination
    • de Almagro MC, Goncharov T, Newton K, Vucic D. Cellular IAP proteins and LUBAC differentially regulate necrosome-associated RIP1 ubiquitination. Cell Death Dis 2015; 6: E1800.
    • (2015) Cell Death Dis , vol.6 , pp. e1800
    • De Almagro, M.C.1    Goncharov, T.2    Newton, K.3    Vucic, D.4
  • 18
    • 84864240409 scopus 로고    scopus 로고
    • The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis
    • Li J, McQuade T, Siemer AB, Napetschnig J, Moriwaki K, Hsiao YS et al. The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis. Cell 2012; 150: 339-350.
    • (2012) Cell , vol.150 , pp. 339-350
    • Li, J.1    McQuade, T.2    Siemer, A.B.3    Napetschnig, J.4    Moriwaki, K.5    Hsiao, Y.S.6
  • 19
    • 84891343566 scopus 로고    scopus 로고
    • Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis
    • Cai Z, Jitkaew S, Zhao J, Chiang HC, Choksi S, Liu J et al. Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis. Nat Cell Biol 2014; 16: 55-65.
    • (2014) Nat Cell Biol , vol.16 , pp. 55-65
    • Cai, Z.1    Jitkaew, S.2    Zhao, J.3    Chiang, H.C.4    Choksi, S.5    Liu, J.6
  • 21
    • 84894024528 scopus 로고    scopus 로고
    • TAK1 kinase switches cell fate from apoptosis to necrosis following TNF stimulation
    • Morioka S, Broglie P, Omori E, Ikeda Y, Takaesu G, Matsumoto K et al. TAK1 kinase switches cell fate from apoptosis to necrosis following TNF stimulation. J Cell Biol 2014; 204: 607-623.
    • (2014) J Cell Biol , vol.204 , pp. 607-623
    • Morioka, S.1    Broglie, P.2    Omori, E.3    Ikeda, Y.4    Takaesu, G.5    Matsumoto, K.6
  • 22
    • 84873033324 scopus 로고    scopus 로고
    • TAK1 is essential for osteoclast differentiation and is an important modulator of cell death by apoptosis and necroptosis
    • Lamothe B, Lai Y, Xie M, Schneider MD, Darnay BG. TAK1 is essential for osteoclast differentiation and is an important modulator of cell death by apoptosis and necroptosis. Mol Cell Biol 2013; 33: 582-595.
    • (2013) Mol Cell Biol , vol.33 , pp. 582-595
    • Lamothe, B.1    Lai, Y.2    Xie, M.3    Schneider, M.D.4    Darnay, B.G.5
  • 23
    • 84927628304 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress induces ligand-independent TNFR1-mediated necroptosis in L929 cells
    • Saveljeva S, Mc Laughlin SL, Vandenabeele P, Samali A, Bertrand MJ. Endoplasmic reticulum stress induces ligand-independent TNFR1-mediated necroptosis in L929 cells. Cell Death Dis 2015; 6: E1587.
    • (2015) Cell Death Dis , vol.6 , pp. e1587
    • Saveljeva, S.1    Mc Laughlin, S.L.2    Vandenabeele, P.3    Samali, A.4    Bertrand, M.J.5
  • 24
    • 77951251430 scopus 로고    scopus 로고
    • Necroptosis as an alternative form of programmed cell death
    • Christofferson DE, Yuan J. Necroptosis as an alternative form of programmed cell death. Curr Opin Cell Biol 2010; 22: 263-268.
    • (2010) Curr Opin Cell Biol , vol.22 , pp. 263-268
    • Christofferson, D.E.1    Yuan, J.2
  • 26
    • 84907197966 scopus 로고    scopus 로고
    • RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis
    • Takahashi N, Vereecke L, Bertrand MJ, Duprez L, Berger SB, Divert T et al. RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis. Nature 2014; 513: 95-99.
    • (2014) Nature , vol.513 , pp. 95-99
    • Takahashi, N.1    Vereecke, L.2    Bertrand, M.J.3    Duprez, L.4    Berger, S.B.5    Divert, T.6
  • 27
  • 28
    • 84859299752 scopus 로고    scopus 로고
    • Rip1 (receptor-interacting protein kinase 1) mediates necroptosis and contributes to renal ischemia/reperfusion injury
    • Linkermann A, Brasen JH, Himmerkus N, Liu S, Huber TB, Kunzendorf U et al. Rip1 (receptor-interacting protein kinase 1) mediates necroptosis and contributes to renal ischemia/reperfusion injury. Kidney Int 2012; 81: 751-761.
    • (2012) Kidney Int , vol.81 , pp. 751-761
    • Linkermann, A.1    Brasen, J.H.2    Himmerkus, N.3    Liu, S.4    Huber, T.B.5    Kunzendorf, U.6
  • 29
    • 84901422731 scopus 로고    scopus 로고
    • RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis
    • Rickard JA, O'Donnell JA, Evans JM, Lalaoui N, Poh AR, Rogers T et al. RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis. Cell 2014; 157: 1175-1188.
    • (2014) Cell , vol.157 , pp. 1175-1188
    • Rickard, J.A.1    O'Donnell, J.A.2    Evans, J.M.3    Lalaoui, N.4    Poh, A.R.5    Rogers, T.6
  • 30
    • 84907833409 scopus 로고    scopus 로고
    • Hematopoietic RIPK1 deficiency results in bone marrow failure caused by apoptosis and RIPK3-mediated necroptosis
    • Roderick JE, Hermance N, Zelic M, Simmons MJ, Polykratis A, Pasparakis M et al. Hematopoietic RIPK1 deficiency results in bone marrow failure caused by apoptosis and RIPK3-mediated necroptosis. Proc Natl Acad Sci USA 2014; 111: 14436-14441.
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. 14436-14441
    • Roderick, J.E.1    Hermance, N.2    Zelic, M.3    Simmons, M.J.4    Polykratis, A.5    Pasparakis, M.6
  • 31
    • 84923880478 scopus 로고    scopus 로고
    • Inflammatory outcomes of apoptosis, necrosis and necroptosis
    • Davidovich P, Kearney CJ, Martin SJ. Inflammatory outcomes of apoptosis, necrosis and necroptosis. Biol Chem 2014; 395: 1163-1171.
    • (2014) Biol Chem , vol.395 , pp. 1163-1171
    • Davidovich, P.1    Kearney, C.J.2    Martin, S.J.3
  • 32
    • 84922602504 scopus 로고    scopus 로고
    • Necroptosis and its role in inflammation
    • Pasparakis M, Vandenabeele P. Necroptosis and its role in inflammation. Nature 2015; 517: 311-320.
    • (2015) Nature , vol.517 , pp. 311-320
    • Pasparakis, M.1    Vandenabeele, P.2
  • 33
    • 17144376810 scopus 로고    scopus 로고
    • High-mobility group box 1 protein (HMGB1): Nuclear weapon in the immune arsenal
    • Lotze MT, Tracey KJ. High-mobility group box 1 protein (HMGB1): Nuclear weapon in the immune arsenal. Nat Rev Immunol 2005; 5: 331-342.
    • (2005) Nat Rev Immunol , vol.5 , pp. 331-342
    • Lotze, M.T.1    Tracey, K.J.2
  • 34
    • 84874263775 scopus 로고    scopus 로고
    • Necroptosis: The release of damageassociated molecular patterns and its physiological relevance
    • Kaczmarek A, Vandenabeele P, Krysko DV. Necroptosis: The release of damageassociated molecular patterns and its physiological relevance. Immunity 2013; 38: 209-223.
    • (2013) Immunity , vol.38 , pp. 209-223
    • Kaczmarek, A.1    Vandenabeele, P.2    Krysko, D.V.3
  • 36
    • 84866151892 scopus 로고    scopus 로고
    • Programmed necrosis: A prominent mechanism of cell death following neonatal brain injury
    • Chavez-Valdez R, Martin LJ, Northington FJ. Programmed necrosis: A prominent mechanism of cell death following neonatal brain injury. Neurol Res Int 2012; 2012: 257563.
    • (2012) Neurol Res Int , vol.2012 , pp. 257563
    • Chavez-Valdez, R.1    Martin, L.J.2    Northington, F.J.3
  • 38
    • 33644840693 scopus 로고    scopus 로고
    • Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury
    • Degterev A, Huang Z, Boyce M, Li Y, Jagtap P, Mizushima N et al. Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat Chem Biol 2005; 1: 112-119.
    • (2005) Nat Chem Biol , vol.1 , pp. 112-119
    • Degterev, A.1    Huang, Z.2    Boyce, M.3    Li, Y.4    Jagtap, P.5    Mizushima, N.6
  • 41
    • 84895508213 scopus 로고    scopus 로고
    • Necroptosis drives motor neuron death in models of both sporadic and familial ALS
    • Re DB, Le Verche V, Yu C, Amoroso MW, Politi KA, Phani S et al. Necroptosis drives motor neuron death in models of both sporadic and familial ALS. Neuron 2014; 81: 1001-1008.
    • (2014) Neuron , vol.81 , pp. 1001-1008
    • Re, D.B.1    Le Verche, V.2    Yu, C.3    Amoroso, M.W.4    Politi, K.A.5    Phani, S.6
  • 42
    • 36248933743 scopus 로고    scopus 로고
    • Necrostatin-1 protects against glutamate-induced glutathione depletion and caspase-independent cell death in HT-22 cells
    • Xu X, Chua CC, Kong J, Kostrzewa RM, Kumaraguru U, Hamdy RC et al. Necrostatin-1 protects against glutamate-induced glutathione depletion and caspase-independent cell death in HT-22 cells. J Neurochem 2007; 103: 2004-2014.
    • (2007) J Neurochem , vol.103 , pp. 2004-2014
    • Xu, X.1    Chua, C.C.2    Kong, J.3    Kostrzewa, R.M.4    Kumaraguru, U.5    Hamdy, R.C.6
  • 43
    • 84954358195 scopus 로고    scopus 로고
    • Necroptosis contributes to the NMDA-induced excitotoxicity in rat's cultured cortical neurons
    • Li Y, Yang X, Ma C, Qiao J, Zhang C. Necroptosis contributes to the NMDA-induced excitotoxicity in rat's cultured cortical neurons. Neurosci Lett 2008; 447: 120-123.
    • (2008) Neurosci Lett , vol.447 , pp. 120-123
    • Li, Y.1    Yang, X.2    Ma, C.3    Qiao, J.4    Zhang, C.5
  • 44
    • 79960111702 scopus 로고    scopus 로고
    • 24(S)-hydroxycholesterol induces neuronal cell death through necroptosis, a form of programmed necrosis
    • Yamanaka K, Saito Y, Yamamori T, Urano Y, Noguchi N. 24(S)-hydroxycholesterol induces neuronal cell death through necroptosis, a form of programmed necrosis. J Biol Chem 2011; 286: 24666-24673.
    • (2011) J Biol Chem , vol.286 , pp. 24666-24673
    • Yamanaka, K.1    Saito, Y.2    Yamamori, T.3    Urano, Y.4    Noguchi, N.5
  • 45
    • 0034904940 scopus 로고    scopus 로고
    • Neurotoxicity of 24-hydroxycholesterol, an important cholesterol elimination product of the brain, may be prevented by Vitamin E and estradiol-17beta
    • Kolsch H, Ludwig M, Lutjohann D, Rao ML. Neurotoxicity of 24-hydroxycholesterol, an important cholesterol elimination product of the brain, may be prevented by vitamin E and estradiol-17beta. J Neural Transm 2001; 108: 475-488.
    • (2001) J Neural Transm , vol.108 , pp. 475-488
    • Kolsch, H.1    Ludwig, M.2    Lutjohann, D.3    Rao, M.L.4
  • 46
    • 84861501372 scopus 로고    scopus 로고
    • Markers of cholesterol metabolism in the brain show stronger associations with cerebrovascular disease than Alzheimer's disease
    • Hughes TM, Kuller LH, Lopez OL, Becker JT, Evans RW, Sutton-Tyrrell K et al. Markers of cholesterol metabolism in the brain show stronger associations with cerebrovascular disease than Alzheimer's disease. J Alzheimers Dis 2012; 30: 53-61.
    • (2012) J Alzheimers Dis , vol.30 , pp. 53-61
    • Hughes, T.M.1    Kuller, L.H.2    Lopez, O.L.3    Becker, J.T.4    Evans, R.W.5    Sutton-Tyrrell, K.6
  • 47
    • 84891771031 scopus 로고    scopus 로고
    • Induction of apoptosis and necroptosis by 24(S)-hydroxycholesterol is dependent on activity of acyl-CoA: Cholesterol acyltransferase 1
    • Yamanaka K, Urano Y, Takabe W, Saito Y, Noguchi N. Induction of apoptosis and necroptosis by 24(S)-hydroxycholesterol is dependent on activity of acyl-CoA: Cholesterol acyltransferase 1. Cell Death Dis 2014; 5: E990.
    • (2014) Cell Death Dis , vol.5 , pp. e990
    • Yamanaka, K.1    Urano, Y.2    Takabe, W.3    Saito, Y.4    Noguchi, N.5
  • 48
  • 49
    • 84892608467 scopus 로고    scopus 로고
    • Cellular inhibitor of apoptosis protein cIAP2 protects against pulmonary tissue necrosis during influenza virus infection to promote host survival
    • Rodrigue-Gervais IG, Labbe K, Dagenais M, Dupaul-Chicoine J, Champagne C, Morizot A et al. Cellular inhibitor of apoptosis protein cIAP2 protects against pulmonary tissue necrosis during influenza virus infection to promote host survival. Cell Host Microbe 2014; 15: 23-35.
    • (2014) Cell Host Microbe , vol.15 , pp. 23-35
    • Rodrigue-Gervais, I.G.1    Labbe, K.2    Dagenais, M.3    Dupaul-Chicoine, J.4    Champagne, C.5    Morizot, A.6
  • 50
    • 84921284050 scopus 로고    scopus 로고
    • Liver-resident macrophage necroptosis orchestrates type 1 microbicidal inflammation and type-2-mediated tissue repair during bacterial infection
    • Bleriot C, Dupuis T, Jouvion G, Eberl G, Disson O, Lecuit M. Liver-resident macrophage necroptosis orchestrates type 1 microbicidal inflammation and type-2-mediated tissue repair during bacterial infection. Immunity 2015; 42: 145-158.
    • (2015) Immunity , vol.42 , pp. 145-158
    • Bleriot, C.1    Dupuis, T.2    Jouvion, G.3    Eberl, G.4    Disson, O.5    Lecuit, M.6
  • 51
    • 84887896349 scopus 로고    scopus 로고
    • Ultrastructural pathology of rat lung injury induced by ischemic acute kidney injury
    • Zang D, Shao Y, Li X. Ultrastructural pathology of rat lung injury induced by ischemic acute kidney injury. Ultrastruct Pathol 2013; 37: 433-439.
    • (2013) Ultrastruct Pathol , vol.37 , pp. 433-439
    • Zang, D.1    Shao, Y.2    Li, X.3
  • 52
    • 84926469754 scopus 로고    scopus 로고
    • Necroptosis and parthanatos are involved in remote lung injury after receiving ischemic renal allografts in rats
    • Zhao H, Ning J, Lemaire A, Koumpa FS, Sun JJ, Fung A et al. Necroptosis and parthanatos are involved in remote lung injury after receiving ischemic renal allografts in rats. Kidney Int 2014; 87: 738-748.
    • (2014) Kidney Int , vol.87 , pp. 738-748
    • Zhao, H.1    Ning, J.2    Lemaire, A.3    Koumpa, F.S.4    Sun, J.J.5    Fung, A.6
  • 54
    • 84888438277 scopus 로고    scopus 로고
    • Widespread mitochondrial depletion via mitophagy does not compromise necroptosis
    • Tait SW, Oberst A, Quarato G, Milasta S, Haller M, Wang R et al. Widespread mitochondrial depletion via mitophagy does not compromise necroptosis. Cell Rep 2013; 5: 878-885.
    • (2013) Cell Rep , vol.5 , pp. 878-885
    • Tait, S.W.1    Oberst, A.2    Quarato, G.3    Milasta, S.4    Haller, M.5    Wang, R.6
  • 55
    • 84916211940 scopus 로고    scopus 로고
    • Red blood cells induce necroptosis of lung endothelial cells and increase susceptibility to lung inflammation
    • Qing DY, Conegliano D, Shashaty MG, Seo J, Reilly JP, Worthen GS et al. Red blood cells induce necroptosis of lung endothelial cells and increase susceptibility to lung inflammation. Am J Respir Crit Care Med 2014; 190: 1243-1254.
    • (2014) Am J Respir Crit Care Med , vol.190 , pp. 1243-1254
    • Qing, D.Y.1    Conegliano, D.2    Shashaty, M.G.3    Seo, J.4    Reilly, J.P.5    Worthen, G.S.6
  • 56
    • 84946094907 scopus 로고    scopus 로고
    • A role for tubular necroptosis in cisplatin-induced AKI
    • e-pub ahead of print 18 March 2015
    • Xu Y, Ma H, Shao J, Wu J, Zhou L, Zhang Z et al. A Role for Tubular Necroptosis in Cisplatin-Induced AKI. J Am Soc Nephrol 2015; e-pub ahead of print 18 March 2015.
    • (2015) J Am Soc Nephrol
    • Xu, Y.1    Ma, H.2    Shao, J.3    Wu, J.4    Zhou, L.5    Zhang, Z.6
  • 61
    • 84899576786 scopus 로고    scopus 로고
    • Combination of necroptosis and apoptosis inhibition enhances cardioprotection against myocardial ischemiareperfusion injury
    • Koshinuma S, Miyamae M, Kaneda K, Kotani J, Figueredo VM. Combination of necroptosis and apoptosis inhibition enhances cardioprotection against myocardial ischemiareperfusion injury. J Anesth 2014; 28: 235-241.
    • (2014) J Anesth , vol.28 , pp. 235-241
    • Koshinuma, S.1    Miyamae, M.2    Kaneda, K.3    Kotani, J.4    Figueredo, V.M.5
  • 62
    • 84860584135 scopus 로고    scopus 로고
    • Inhibition of RIP1-dependent necrosis prevents adverse cardiac remodeling after myocardial ischemia-reperfusion in vivo
    • Oerlemans MI, Liu J, Arslan F, den Ouden K, van Middelaar BJ, Doevendans PA et al. Inhibition of RIP1-dependent necrosis prevents adverse cardiac remodeling after myocardial ischemia-reperfusion in vivo. Basic Res Cardiol 2012; 107: 270.
    • (2012) Basic Res Cardiol , vol.107 , pp. 270
    • Oerlemans, M.I.1    Liu, J.2    Arslan, F.3    Den Ouden, K.4    Van Middelaar, B.J.5    Doevendans, P.A.6
  • 63
    • 84873152891 scopus 로고    scopus 로고
    • A role of RIP3-mediated macrophage necrosis in atherosclerosis development
    • Lin J, Li H, Yang M, Ren J, Huang Z, Han F et al. A role of RIP3-mediated macrophage necrosis in atherosclerosis development. Cell Rep 2013; 3: 200-210.
    • (2013) Cell Rep , vol.3 , pp. 200-210
    • Lin, J.1    Li, H.2    Yang, M.3    Ren, J.4    Huang, Z.5    Han, F.6
  • 64
    • 84907210946 scopus 로고    scopus 로고
    • RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis
    • Dannappel M, Vlantis K, Kumari S, Polykratis A, Kim C, Wachsmuth L et al. RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis. Nature 2014; 513: 90-94.
    • (2014) Nature , vol.513 , pp. 90-94
    • Dannappel, M.1    Vlantis, K.2    Kumari, S.3    Polykratis, A.4    Kim, C.5    Wachsmuth, L.6
  • 65
    • 84893726744 scopus 로고    scopus 로고
    • Necroptosis is active in children with inflammatory bowel disease and contributes to heighten intestinal inflammation
    • Pierdomenico M, Negroni A, Stronati L, Vitali R, Prete E, Bertin J et al. Necroptosis is active in children with inflammatory bowel disease and contributes to heighten intestinal inflammation. Am J Gastroenterol 2014; 109: 279-287.
    • (2014) Am J Gastroenterol , vol.109 , pp. 279-287
    • Pierdomenico, M.1    Negroni, A.2    Stronati, L.3    Vitali, R.4    Prete, E.5    Bertin, J.6
  • 68
    • 80052845560 scopus 로고    scopus 로고
    • Caspase-8 regulates TNF-αlpha-induced epithelial necroptosis and terminal ileitis
    • Gunther C, Martini E, Wittkopf N, Amann K, Weigmann B, Neumann H et al. Caspase-8 regulates TNF-αlpha-induced epithelial necroptosis and terminal ileitis. Nature 2011; 477: 335-339.
    • (2011) Nature , vol.477 , pp. 335-339
    • Gunther, C.1    Martini, E.2    Wittkopf, N.3    Amann, K.4    Weigmann, B.5    Neumann, H.6
  • 69
    • 84863784919 scopus 로고    scopus 로고
    • Inhibition of apoptosis protects mice from ethanol-mediated acceleration of early markers of CCl4-induced fibrosis but not steatosis or inflammation
    • Roychowdhury S, Chiang DJ, Mandal P, McMullen MR, Liu X, Cohen JI et al. Inhibition of apoptosis protects mice from ethanol-mediated acceleration of early markers of CCl4-induced fibrosis but not steatosis or inflammation. Alcohol Clin Exp Res 2012; 36: 1139-1147.
    • (2012) Alcohol Clin Exp Res , vol.36 , pp. 1139-1147
    • Roychowdhury, S.1    Chiang, D.J.2    Mandal, P.3    McMullen, M.R.4    Liu, X.5    Cohen, J.I.6
  • 71
    • 84919465499 scopus 로고    scopus 로고
    • Cell death and cell death responses in liver disease: Mechanisms and clinical relevance
    • Luedde T, Kaplowitz N, Schwabe RF. Cell death and cell death responses in liver disease: Mechanisms and clinical relevance. Gastroenterology 2014; 147: 765-783 e764.
    • (2014) Gastroenterology , vol.147 , pp. 765-783e764
    • Luedde, T.1    Kaplowitz, N.2    Schwabe, R.F.3
  • 72
    • 84907751865 scopus 로고    scopus 로고
    • Necrostatin-1 protects against reactive oxygen species (ROS)-induced hepatotoxicity in acetaminopheninduced acute liver failure
    • Takemoto K, Hatano E, Iwaisako K, Takeiri M, Noma N, Ohmae S et al. Necrostatin-1 protects against reactive oxygen species (ROS)-induced hepatotoxicity in acetaminopheninduced acute liver failure. FEBS Open Bio 2014; 4: 777-787.
    • (2014) FEBS Open Bio , vol.4 , pp. 777-787
    • Takemoto, K.1    Hatano, E.2    Iwaisako, K.3    Takeiri, M.4    Noma, N.5    Ohmae, S.6
  • 73
    • 84946824966 scopus 로고    scopus 로고
    • Acetaminophen/paracetamol: A history of errors, failures and false decisions
    • Brune K, Renner B, Tiegs G. Acetaminophen/paracetamol: A history of errors, failures and false decisions. Eur J Pain 2014; 19: 953-965.
    • (2014) Eur J Pain , vol.19 , pp. 953-965
    • Brune, K.1    Renner, B.2    Tiegs, G.3
  • 74
    • 61849117309 scopus 로고    scopus 로고
    • Human basophils and eosinophils are the direct target leukocytes of the novel IL-1 family member IL-33
    • Pecaric-Petkovic T, Didichenko SA, Kaempfer S, Spiegl N, Dahinden CA. Human basophils and eosinophils are the direct target leukocytes of the novel IL-1 family member IL-33. Blood 2009; 113: 1526-1534.
    • (2009) Blood , vol.113 , pp. 1526-1534
    • Pecaric-Petkovic, T.1    Didichenko, S.A.2    Kaempfer, S.3    Spiegl, N.4    Dahinden, C.A.5
  • 75
    • 84907217921 scopus 로고    scopus 로고
    • Hepatitis C virus-induced hepatocyte cell death and protection by inhibition of apoptosis
    • Lim EJ, El Khobar K, Chin R, Earnest-Silveira L, Angus PW, Bock CT et al. Hepatitis C virus-induced hepatocyte cell death and protection by inhibition of apoptosis. J Gen Virol 2014; 95(Pt 10): 2204-2215.
    • (2014) J Gen Virol , vol.95 , pp. 2204-2215
    • Lim, E.J.1    El Khobar, K.2    Chin, R.3    Earnest-Silveira, L.4    Angus, P.W.5    Bock, C.T.6
  • 76
    • 84899019365 scopus 로고    scopus 로고
    • Hepatocyte necroptosis induced by ischemic acute kidney injury in rats
    • Bao C, Shao Y, Li X. Hepatocyte necroptosis induced by ischemic acute kidney injury in rats. Ultrastruct Pathol 2014; 38: 217-223.
    • (2014) Ultrastruct Pathol , vol.38 , pp. 217-223
    • Bao, C.1    Shao, Y.2    Li, X.3
  • 77
    • 66749183275 scopus 로고    scopus 로고
    • Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-αlpha
    • He S, Wang L, Miao L, Wang T, Du F, Zhao L et al. Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-αlpha. Cell 2009; 137: 1100-1111.
    • (2009) Cell , vol.137 , pp. 1100-1111
    • He, S.1    Wang, L.2    Miao, L.3    Wang, T.4    Du, F.5    Zhao, L.6
  • 78
    • 67650812332 scopus 로고    scopus 로고
    • RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis
    • Zhang DW, Shao J, Lin J, Zhang N, Lu BJ, Lin SC et al. RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. Science 2009; 325: 332-336.
    • (2009) Science , vol.325 , pp. 332-336
    • Zhang, D.W.1    Shao, J.2    Lin, J.3    Zhang, N.4    Lu, B.J.5    Lin, S.C.6
  • 79
    • 84862175306 scopus 로고    scopus 로고
    • Dichotomy between RIP1- and RIP3-mediated necroptosis in tumor necrosis factor-alphainduced shock
    • Linkermann A, Brasen JH, De Zen F, Weinlich R, Schwendener RA, Green DR et al. Dichotomy between RIP1- and RIP3-mediated necroptosis in tumor necrosis factor-alphainduced shock. Mol Med 2012; 18: 577-586.
    • (2012) Mol Med , vol.18 , pp. 577-586
    • Linkermann, A.1    Brasen, J.H.2    De Zen, F.3    Weinlich, R.4    Schwendener, R.A.5    Green, D.R.6
  • 80
    • 84881184694 scopus 로고    scopus 로고
    • Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis
    • Wu J, Huang Z, Ren J, Zhang Z, He P, Li Y et al. Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis. Cell Res 2013; 23: 994-1006.
    • (2013) Cell Res , vol.23 , pp. 994-1006
    • Wu, J.1    Huang, Z.2    Ren, J.3    Zhang, Z.4    He, P.5    Li, Y.6
  • 81
    • 84908128377 scopus 로고    scopus 로고
    • The necroptosis adaptor RIPK3 promotes injury-induced cytokine expression and tissue repair
    • Moriwaki K, Balaji S, McQuade T, Malhotra N, Kang J, Chan FK. The necroptosis adaptor RIPK3 promotes injury-induced cytokine expression and tissue repair. Immunity 2014; 41: 567-578.
    • (2014) Immunity , vol.41 , pp. 567-578
    • Moriwaki, K.1    Balaji, S.2    McQuade, T.3    Malhotra, N.4    Kang, J.5    Chan, F.K.6
  • 83
    • 84869024586 scopus 로고    scopus 로고
    • New components of the necroptotic pathway
    • Zhou Z, Han V, Han J. New components of the necroptotic pathway. Protein Cell 2012; 3: 811-817.
    • (2012) Protein Cell , vol.3 , pp. 811-817
    • Zhou, Z.1    Han, V.2    Han, J.3
  • 84
    • 78650718758 scopus 로고    scopus 로고
    • Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis
    • Trichonas G, Murakami Y, Thanos A, Morizane Y, Kayama M, Debouck CM et al. Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis. Proc Natl Acad Sci USA 2010; 107: 21695-21700.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 21695-21700
    • Trichonas, G.1    Murakami, Y.2    Thanos, A.3    Morizane, Y.4    Kayama, M.5    Debouck, C.M.6
  • 85
    • 76749109832 scopus 로고    scopus 로고
    • RIP1's function in NF-kappaB activation: From master actor to onlooker
    • Bertrand MJ, Vandenabeele P. RIP1's function in NF-kappaB activation: From master actor to onlooker. Cell Death Differ 2010; 17: 379-380.
    • (2010) Cell Death Differ , vol.17 , pp. 379-380
    • Bertrand, M.J.1    Vandenabeele, P.2
  • 86
    • 84870570760 scopus 로고    scopus 로고
    • Necrostatin-1 analogues: Critical issues on the specificity, activity and in vivo use in experimental disease models
    • Takahashi N, Duprez L, Grootjans S, Cauwels A, Nerinckx W, DuHadaway JB et al. Necrostatin-1 analogues: Critical issues on the specificity, activity and in vivo use in experimental disease models. Cell Death Dis 2012; 3: E437.
    • (2012) Cell Death Dis , vol.3 , pp. e437
    • Takahashi, N.1    Duprez, L.2    Grootjans, S.3    Cauwels, A.4    Nerinckx, W.5    DuHadaway, J.B.6
  • 87
    • 84886305117 scopus 로고    scopus 로고
    • Regulation of RIP1 kinase signalling at the crossroads of inflammation and cell death
    • Ofengeim D, Yuan J. Regulation of RIP1 kinase signalling at the crossroads of inflammation and cell death. Nat Rev Mol Cell Biol 2013; 14: 727-736.
    • (2013) Nat Rev Mol Cell Biol , vol.14 , pp. 727-736
    • Ofengeim, D.1    Yuan, J.2
  • 88
    • 84874860953 scopus 로고    scopus 로고
    • Structural basis of RIP1 inhibition by necrostatins
    • Xie T, Peng W, Liu Y, Yan C, Maki J, Degterev A et al. Structural basis of RIP1 inhibition by necrostatins. Structure 2013; 21: 493-499.
    • (2013) Structure , vol.21 , pp. 493-499
    • Xie, T.1    Peng, W.2    Liu, Y.3    Yan, C.4    Maki, J.5    Degterev, A.6
  • 89
    • 58749100879 scopus 로고    scopus 로고
    • Receptor-interacting protein homotypic interaction motif-dependent control of NF-kappa B activation via the DNA-dependent activator of IFN regulatory factors
    • Kaiser WJ, Upton JW, Mocarski ES. Receptor-interacting protein homotypic interaction motif-dependent control of NF-kappa B activation via the DNA-dependent activator of IFN regulatory factors. J Immunol 2008; 181: 6427-6434.
    • (2008) J Immunol , vol.181 , pp. 6427-6434
    • Kaiser, W.J.1    Upton, J.W.2    Mocarski, E.S.3
  • 90
    • 84872310440 scopus 로고    scopus 로고
    • Activity and specificity of necrostatin-1, small-molecule inhibitor of RIP1 kinase
    • Degterev A, Maki JL, Yuan J. Activity and specificity of necrostatin-1, small-molecule inhibitor of RIP1 kinase. Cell Death Differ 2013; 20: 366.
    • (2013) Cell Death Differ , vol.20 , pp. 366
    • Degterev, A.1    Maki, J.L.2    Yuan, J.3
  • 92
    • 84890534620 scopus 로고    scopus 로고
    • Discovery of small molecule RIP1 kinase inhibitors for the treatment of pathologies associated with necroptosis
    • Harris PA, Bandyopadhyay D, Berger SB, Campobasso N, Capriotti CA, Cox JA et al. Discovery of small molecule RIP1 kinase inhibitors for the treatment of pathologies associated with necroptosis. ACS Med Chem Lett 2013; 4: 1238-1243.
    • (2013) ACS Med Chem Lett , vol.4 , pp. 1238-1243
    • Harris, P.A.1    Bandyopadhyay, D.2    Berger, S.B.3    Campobasso, N.4    Capriotti, C.A.5    Cox, J.A.6
  • 94
    • 84912106351 scopus 로고    scopus 로고
    • RIP3 induces apoptosis independent of pronecrotic kinase activity
    • Mandal P, Berger SB, Pillay S, Moriwaki K, Huang C, Guo H et al. RIP3 induces apoptosis independent of pronecrotic kinase activity. Mol Cell 2014; 56: 481-495.
    • (2014) Mol Cell , vol.56 , pp. 481-495
    • Mandal, P.1    Berger, S.B.2    Pillay, S.3    Moriwaki, K.4    Huang, C.5    Guo, H.6
  • 95
    • 84928128217 scopus 로고    scopus 로고
    • A cytosolic heat shock protein 90 and cochaperone CDC37 complex is required for RIP3 activation during necroptosis
    • Li D, Xu T, Cao Y, Wang H, Li L, Chen S et al. A cytosolic heat shock protein 90 and cochaperone CDC37 complex is required for RIP3 activation during necroptosis. Proc Natl Acad Sci USA 2015; 112: 5017-5022.
    • (2015) Proc Natl Acad Sci USA , vol.112 , pp. 5017-5022
    • Li, D.1    Xu, T.2    Cao, Y.3    Wang, H.4    Li, L.5    Chen, S.6
  • 97
    • 84922394053 scopus 로고    scopus 로고
    • Regulated cell death and inflammation: An auto-amplification loop causes organ failure
    • Linkermann A, Stockwell BR, Krautwald S, Anders HJ. Regulated cell death and inflammation: An auto-amplification loop causes organ failure. Nat Rev Immunol 2014; 14: 759-767.
    • (2014) Nat Rev Immunol , vol.14 , pp. 759-767
    • Linkermann, A.1    Stockwell, B.R.2    Krautwald, S.3    Anders, H.J.4
  • 100
    • 84935699564 scopus 로고    scopus 로고
    • Necroptosis suppresses inflammation via termination of TNF- or LPS-induced cytokine and chemokine production
    • Kearney CJ, Cullen SP, Tynan GA, Henry CM, Clancy D, Lavelle EC et al. Necroptosis suppresses inflammation via termination of TNF- or LPS-induced cytokine and chemokine production. Cell Death Differ 2015; 22: 1313-1327.
    • (2015) Cell Death Differ , vol.22 , pp. 1313-1327
    • Kearney, C.J.1    Cullen, S.P.2    Tynan, G.A.3    Henry, C.M.4    Clancy, D.5    Lavelle, E.C.6
  • 101
    • 84881375174 scopus 로고    scopus 로고
    • Xenon treatment protects against cold ischemia associated delayed graft function and prolongs graft survival in rats
    • Zhao H, Watts HR, Chong M, Huang H, Tralau-Stewart C, Maxwell PH et al. Xenon treatment protects against cold ischemia associated delayed graft function and prolongs graft survival in rats. Am J Transplant 2013; 13: 2006-2018.
    • (2013) Am J Transplant , vol.13 , pp. 2006-2018
    • Zhao, H.1    Watts, H.R.2    Chong, M.3    Huang, H.4    Tralau-Stewart, C.5    Maxwell, P.H.6
  • 102
    • 84878258145 scopus 로고    scopus 로고
    • The role of HMGB1 in inflammation-mediated organ injury
    • Asavarut P, Zhao H, Gu J, Ma D. The role of HMGB1 in inflammation-mediated organ injury. Acta Anaesthesiol Taiwan 2013; 51: 28-33.
    • (2013) Acta Anaesthesiol Taiwan , vol.51 , pp. 28-33
    • Asavarut, P.1    Zhao, H.2    Gu, J.3    Ma, D.4
  • 105
    • 84920439936 scopus 로고    scopus 로고
    • The P2X1 receptor is required for neutrophil extravasation during lipopolysaccharide-induced lethal endotoxemia in mice
    • Maitre B, Magnenat S, Heim V, Ravanat C, Evans RJ, de la Salle H et al. The P2X1 receptor is required for neutrophil extravasation during lipopolysaccharide-induced lethal endotoxemia in mice. J Immunol 2015; 194: 739-749.
    • (2015) J Immunol , vol.194 , pp. 739-749
    • Maitre, B.1    Magnenat, S.2    Heim, V.3    Ravanat, C.4    Evans, R.J.5    De La Salle, H.6
  • 106
    • 84902187683 scopus 로고    scopus 로고
    • Deletion of CD24 impairs development of heat shock protein gp96-driven autoimmune disease through expansion of myeloid-derived suppressor cells
    • Thaxton JE, Liu B, Zheng P, Liu Y, Li Z. Deletion of CD24 impairs development of heat shock protein gp96-driven autoimmune disease through expansion of myeloid-derived suppressor cells. J Immunol 2014; 192: 5679-5686.
    • (2014) J Immunol , vol.192 , pp. 5679-5686
    • Thaxton, J.E.1    Liu, B.2    Zheng, P.3    Liu, Y.4    Li, Z.5
  • 107
    • 84900525694 scopus 로고    scopus 로고
    • Role of Toll-like receptor-4 in renal graft ischemia-reperfusion injury
    • Zhao H, Perez JS, Lu K, George AJ, Ma D. Role of Toll-like receptor-4 in renal graft ischemia-reperfusion injury. Am J Physiol Renal Physiol 2014; 306: F801-F811.
    • (2014) Am J Physiol Renal Physiol , vol.306 , pp. F801-F811
    • Zhao, H.1    Perez, J.S.2    Lu, K.3    George, A.J.4    Ma, D.5
  • 108
    • 84930829907 scopus 로고    scopus 로고
    • Mitochondrial DNA damage-associated molecular patterns mediate a feed-forward cycle of bacteriainduced vascular injury in perfused rat lungs
    • Kuck JL, Obiako BO, Gorodnya OM, Pastukh VM, Kua J, Simmons JD et al. Mitochondrial DNA damage-associated molecular patterns mediate a feed-forward cycle of bacteriainduced vascular injury in perfused rat lungs. Am J Physiol Lung Cell Mol Physiol 2015; 308: L1078-L1085.
    • (2015) Am J Physiol Lung Cell Mol Physiol , vol.308 , pp. L1078-L1085
    • Kuck, J.L.1    Obiako, B.O.2    Gorodnya, O.M.3    Pastukh, V.M.4    Kua, J.5    Simmons, J.D.6
  • 109
    • 79952339508 scopus 로고    scopus 로고
    • Dangers within: DAMP responses to damage and cell death in kidney disease
    • Rosin DL, Okusa MD. Dangers within: DAMP responses to damage and cell death in kidney disease. J Am Soc Nephrol 2011; 22: 416-425.
    • (2011) J Am Soc Nephrol , vol.22 , pp. 416-425
    • Rosin, D.L.1    Okusa, M.D.2
  • 111
    • 80053075831 scopus 로고    scopus 로고
    • Cyclophilin A is a damage-associated molecular pattern molecule that mediates acetaminophen-induced liver injury
    • Dear JW, Simpson KJ, Nicolai MP, Catterson JH, Street J, Huizinga T et al. Cyclophilin A is a damage-associated molecular pattern molecule that mediates acetaminophen-induced liver injury. J Immunol 2011; 187: 3347-3352.
    • (2011) J Immunol , vol.187 , pp. 3347-3352
    • Dear, J.W.1    Simpson, K.J.2    Nicolai, M.P.3    Catterson, J.H.4    Street, J.5    Huizinga, T.6
  • 112
    • 78349309166 scopus 로고    scopus 로고
    • Cyclophilin A release as a biomarker of necrotic cell death
    • Christofferson DE, Yuan J. Cyclophilin A release as a biomarker of necrotic cell death. Cell Death Differ 2010; 17: 1942-1943.
    • (2010) Cell Death Differ , vol.17 , pp. 1942-1943
    • Christofferson, D.E.1    Yuan, J.2


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