-
2
-
-
0036651535
-
Cell death: Apoptosis versus necrosis (review)
-
Kanduc D, Mittelman A, Serpico R, Sinigaglia E, Sinha AA, Natale C et al. Cell death: Apoptosis versus necrosis (review). Int J Oncol 2002; 21: 165-170.
-
(2002)
Int J Oncol
, vol.21
, pp. 165-170
-
-
Kanduc, D.1
Mittelman, A.2
Serpico, R.3
Sinigaglia, E.4
Sinha, A.A.5
Natale, C.6
-
3
-
-
84897088275
-
Activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis
-
Newton K, Dugger DL, Wickliffe KE, Kapoor N, de Almagro MC, Vucic D et al. Activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis. Science 2014; 343: 1357-1360.
-
(2014)
Science
, vol.343
, pp. 1357-1360
-
-
Newton, K.1
Dugger, D.L.2
Wickliffe, K.E.3
Kapoor, N.4
De Almagro, M.C.5
Vucic, D.6
-
4
-
-
84862907788
-
Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase
-
Sun L, Wang H, Wang Z, He S, Chen S, Liao D et al. Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase. Cell 2012; 148: 213-227.
-
(2012)
Cell
, vol.148
, pp. 213-227
-
-
Sun, L.1
Wang, H.2
Wang, Z.3
He, S.4
Chen, S.5
Liao, D.6
-
5
-
-
84904322380
-
RIP3, a kinase promoting necroptotic cell death, mediates adverse remodelling after myocardial infarction
-
Luedde M, Lutz M, Carter N, Sosna J, Jacoby C, Vucur M et al. RIP3, a kinase promoting necroptotic cell death, mediates adverse remodelling after myocardial infarction. Cardiovasc Res 2014; 103: 206-216.
-
(2014)
Cardiovasc Res
, vol.103
, pp. 206-216
-
-
Luedde, M.1
Lutz, M.2
Carter, N.3
Sosna, J.4
Jacoby, C.5
Vucur, M.6
-
6
-
-
50249132439
-
Necrostatin-1 reduces histopathology and improves functional outcome after controlled cortical impact in mice
-
You Z, Savitz SI, Yang J, Degterev A, Yuan J, Cuny GD et al. Necrostatin-1 reduces histopathology and improves functional outcome after controlled cortical impact in mice. J Cereb Blood Flow Metab 2008; 28: 1564-1573.
-
(2008)
J Cereb Blood Flow Metab
, vol.28
, pp. 1564-1573
-
-
You, Z.1
Savitz, S.I.2
Yang, J.3
Degterev, A.4
Yuan, J.5
Cuny, G.D.6
-
8
-
-
84904562812
-
RIPK3-mediated necroptosis regulates cardiac allograft rejection
-
Pavlosky A, Lau A, Su Y, Lian D, Huang X, Yin Z et al. RIPK3-mediated necroptosis regulates cardiac allograft rejection. Am J Transplant 2014; 14: 1778-1790.
-
(2014)
Am J Transplant
, vol.14
, pp. 1778-1790
-
-
Pavlosky, A.1
Lau, A.2
Su, Y.3
Lian, D.4
Huang, X.5
Yin, Z.6
-
9
-
-
84886796430
-
RIPK3-mediated necroptosis promotes donor kidney inflammatory injury and reduces allograft survival
-
Lau A, Wang S, Jiang J, Haig A, Pavlosky A, Linkermann A et al. RIPK3-mediated necroptosis promotes donor kidney inflammatory injury and reduces allograft survival. Am J Transplant 2013; 13: 2805-2818.
-
(2013)
Am J Transplant
, vol.13
, pp. 2805-2818
-
-
Lau, A.1
Wang, S.2
Jiang, J.3
Haig, A.4
Pavlosky, A.5
Linkermann, A.6
-
10
-
-
67650638892
-
RIP kinases at the crossroads of cell death and survival
-
Declercq W, Vanden Berghe T, Vandenabeele P. RIP kinases at the crossroads of cell death and survival. Cell 2009; 138: 229-232.
-
(2009)
Cell
, vol.138
, pp. 229-232
-
-
Declercq, W.1
Vanden Berghe, T.2
Vandenabeele, P.3
-
11
-
-
0036781052
-
NF-kappaB regulation in the immune system
-
Li Q, Verma IM. NF-kappaB regulation in the immune system. Nat Rev Immunol 2002; 2: 725-734.
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 725-734
-
-
Li, Q.1
Verma, I.M.2
-
12
-
-
83155192804
-
TNF-induced necroptosis in L929 cells is tightly regulated by multiple TNFR1 complex I and II members
-
Vanlangenakker N, Bertrand MJ, Bogaert P, Vandenabeele P, Vanden Berghe T. TNF-induced necroptosis in L929 cells is tightly regulated by multiple TNFR1 complex I and II members. Cell Death Dis 2011; 2: E230.
-
(2011)
Cell Death Dis
, vol.2
, pp. e230
-
-
Vanlangenakker, N.1
Bertrand, M.J.2
Bogaert, P.3
Vandenabeele, P.4
Vanden Berghe, T.5
-
13
-
-
79952623655
-
CIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3- dependent reactive oxygen species production
-
Vanlangenakker N, Vanden Berghe T, Bogaert P, Laukens B, Zobel K, Deshayes K et al. cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3- dependent reactive oxygen species production. Cell Death Differ 2011; 18: 656-665.
-
(2011)
Cell Death Differ
, vol.18
, pp. 656-665
-
-
Vanlangenakker, N.1
Vanden Berghe, T.2
Bogaert, P.3
Laukens, B.4
Zobel, K.5
Deshayes, K.6
-
14
-
-
57649181391
-
Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway
-
Hitomi J, Christofferson DE, Ng A, Yao J, Degterev A, Xavier RJ et al. Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway. Cell 2008; 135: 1311-1323.
-
(2008)
Cell
, vol.135
, pp. 1311-1323
-
-
Hitomi, J.1
Christofferson, D.E.2
Ng, A.3
Yao, J.4
Degterev, A.5
Xavier, R.J.6
-
15
-
-
84884823502
-
CYLD deubiquitinates RIP1 in the TNFalpha-induced necrosome to facilitate kinase activation and programmed necrosis
-
Moquin DM, McQuade T, Chan FK. CYLD deubiquitinates RIP1 in the TNFalpha-induced necrosome to facilitate kinase activation and programmed necrosis. PLoS One 2013; 8: E76841.
-
(2013)
PLoS One
, vol.8
, pp. e76841
-
-
Moquin, D.M.1
McQuade, T.2
Chan, F.K.3
-
16
-
-
84989885436
-
Cellular IAP proteins and LUBAC differentially regulate necrosome-associated RIP1 ubiquitination
-
de Almagro MC, Goncharov T, Newton K, Vucic D. Cellular IAP proteins and LUBAC differentially regulate necrosome-associated RIP1 ubiquitination. Cell Death Dis 2015; 6: E1800.
-
(2015)
Cell Death Dis
, vol.6
, pp. e1800
-
-
De Almagro, M.C.1
Goncharov, T.2
Newton, K.3
Vucic, D.4
-
17
-
-
84856160569
-
Caspase 8 inhibits programmed necrosis by processing CYLD
-
O'Donnell MA, Perez-Jimenez E, Oberst A, Ng A, Massoumi R, Xavier R et al. Caspase 8 inhibits programmed necrosis by processing CYLD. Nat Cell Biol 2011; 13: 1437-1442.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 1437-1442
-
-
O'Donnell, M.A.1
Perez-Jimenez, E.2
Oberst, A.3
Ng, A.4
Massoumi, R.5
Xavier, R.6
-
18
-
-
84864240409
-
The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis
-
Li J, McQuade T, Siemer AB, Napetschnig J, Moriwaki K, Hsiao YS et al. The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis. Cell 2012; 150: 339-350.
-
(2012)
Cell
, vol.150
, pp. 339-350
-
-
Li, J.1
McQuade, T.2
Siemer, A.B.3
Napetschnig, J.4
Moriwaki, K.5
Hsiao, Y.S.6
-
19
-
-
84891343566
-
Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis
-
Cai Z, Jitkaew S, Zhao J, Chiang HC, Choksi S, Liu J et al. Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis. Nat Cell Biol 2014; 16: 55-65.
-
(2014)
Nat Cell Biol
, vol.16
, pp. 55-65
-
-
Cai, Z.1
Jitkaew, S.2
Zhao, J.3
Chiang, H.C.4
Choksi, S.5
Liu, J.6
-
20
-
-
84880357849
-
Two independent pathways of regulated necrosis mediate ischemia-reperfusion injury
-
Linkermann A, Brasen JH, Darding M, Jin MK, Sanz AB, Heller JO et al. Two independent pathways of regulated necrosis mediate ischemia-reperfusion injury. Proc Natl Acad Sci USA 2013; 110: 12024-12029.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 12024-12029
-
-
Linkermann, A.1
Brasen, J.H.2
Darding, M.3
Jin, M.K.4
Sanz, A.B.5
Heller, J.O.6
-
21
-
-
84894024528
-
TAK1 kinase switches cell fate from apoptosis to necrosis following TNF stimulation
-
Morioka S, Broglie P, Omori E, Ikeda Y, Takaesu G, Matsumoto K et al. TAK1 kinase switches cell fate from apoptosis to necrosis following TNF stimulation. J Cell Biol 2014; 204: 607-623.
-
(2014)
J Cell Biol
, vol.204
, pp. 607-623
-
-
Morioka, S.1
Broglie, P.2
Omori, E.3
Ikeda, Y.4
Takaesu, G.5
Matsumoto, K.6
-
22
-
-
84873033324
-
TAK1 is essential for osteoclast differentiation and is an important modulator of cell death by apoptosis and necroptosis
-
Lamothe B, Lai Y, Xie M, Schneider MD, Darnay BG. TAK1 is essential for osteoclast differentiation and is an important modulator of cell death by apoptosis and necroptosis. Mol Cell Biol 2013; 33: 582-595.
-
(2013)
Mol Cell Biol
, vol.33
, pp. 582-595
-
-
Lamothe, B.1
Lai, Y.2
Xie, M.3
Schneider, M.D.4
Darnay, B.G.5
-
23
-
-
84927628304
-
Endoplasmic reticulum stress induces ligand-independent TNFR1-mediated necroptosis in L929 cells
-
Saveljeva S, Mc Laughlin SL, Vandenabeele P, Samali A, Bertrand MJ. Endoplasmic reticulum stress induces ligand-independent TNFR1-mediated necroptosis in L929 cells. Cell Death Dis 2015; 6: E1587.
-
(2015)
Cell Death Dis
, vol.6
, pp. e1587
-
-
Saveljeva, S.1
Mc Laughlin, S.L.2
Vandenabeele, P.3
Samali, A.4
Bertrand, M.J.5
-
24
-
-
77951251430
-
Necroptosis as an alternative form of programmed cell death
-
Christofferson DE, Yuan J. Necroptosis as an alternative form of programmed cell death. Curr Opin Cell Biol 2010; 22: 263-268.
-
(2010)
Curr Opin Cell Biol
, vol.22
, pp. 263-268
-
-
Christofferson, D.E.1
Yuan, J.2
-
25
-
-
84901386193
-
RIPK1 blocks early postnatal lethality mediated by caspase-8 and RIPK3
-
Dillon CP, Weinlich R, Rodriguez DA, Cripps JG, Quarato G, Gurung P et al. RIPK1 blocks early postnatal lethality mediated by caspase-8 and RIPK3. Cell 2014; 157: 1189-1202.
-
(2014)
Cell
, vol.157
, pp. 1189-1202
-
-
Dillon, C.P.1
Weinlich, R.2
Rodriguez, D.A.3
Cripps, J.G.4
Quarato, G.5
Gurung, P.6
-
26
-
-
84907197966
-
RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis
-
Takahashi N, Vereecke L, Bertrand MJ, Duprez L, Berger SB, Divert T et al. RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis. Nature 2014; 513: 95-99.
-
(2014)
Nature
, vol.513
, pp. 95-99
-
-
Takahashi, N.1
Vereecke, L.2
Bertrand, M.J.3
Duprez, L.4
Berger, S.B.5
Divert, T.6
-
27
-
-
84901649808
-
RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition
-
Kaiser WJ, Daley-Bauer LP, Thapa RJ, Mandal P, Berger SB, Huang C et al. RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition. Proc Natl Acad Sci USA 2014; 111: 7753-7758.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 7753-7758
-
-
Kaiser, W.J.1
Daley-Bauer, L.P.2
Thapa, R.J.3
Mandal, P.4
Berger, S.B.5
Huang, C.6
-
28
-
-
84859299752
-
Rip1 (receptor-interacting protein kinase 1) mediates necroptosis and contributes to renal ischemia/reperfusion injury
-
Linkermann A, Brasen JH, Himmerkus N, Liu S, Huber TB, Kunzendorf U et al. Rip1 (receptor-interacting protein kinase 1) mediates necroptosis and contributes to renal ischemia/reperfusion injury. Kidney Int 2012; 81: 751-761.
-
(2012)
Kidney Int
, vol.81
, pp. 751-761
-
-
Linkermann, A.1
Brasen, J.H.2
Himmerkus, N.3
Liu, S.4
Huber, T.B.5
Kunzendorf, U.6
-
29
-
-
84901422731
-
RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis
-
Rickard JA, O'Donnell JA, Evans JM, Lalaoui N, Poh AR, Rogers T et al. RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis. Cell 2014; 157: 1175-1188.
-
(2014)
Cell
, vol.157
, pp. 1175-1188
-
-
Rickard, J.A.1
O'Donnell, J.A.2
Evans, J.M.3
Lalaoui, N.4
Poh, A.R.5
Rogers, T.6
-
30
-
-
84907833409
-
Hematopoietic RIPK1 deficiency results in bone marrow failure caused by apoptosis and RIPK3-mediated necroptosis
-
Roderick JE, Hermance N, Zelic M, Simmons MJ, Polykratis A, Pasparakis M et al. Hematopoietic RIPK1 deficiency results in bone marrow failure caused by apoptosis and RIPK3-mediated necroptosis. Proc Natl Acad Sci USA 2014; 111: 14436-14441.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 14436-14441
-
-
Roderick, J.E.1
Hermance, N.2
Zelic, M.3
Simmons, M.J.4
Polykratis, A.5
Pasparakis, M.6
-
31
-
-
84923880478
-
Inflammatory outcomes of apoptosis, necrosis and necroptosis
-
Davidovich P, Kearney CJ, Martin SJ. Inflammatory outcomes of apoptosis, necrosis and necroptosis. Biol Chem 2014; 395: 1163-1171.
-
(2014)
Biol Chem
, vol.395
, pp. 1163-1171
-
-
Davidovich, P.1
Kearney, C.J.2
Martin, S.J.3
-
32
-
-
84922602504
-
Necroptosis and its role in inflammation
-
Pasparakis M, Vandenabeele P. Necroptosis and its role in inflammation. Nature 2015; 517: 311-320.
-
(2015)
Nature
, vol.517
, pp. 311-320
-
-
Pasparakis, M.1
Vandenabeele, P.2
-
33
-
-
17144376810
-
High-mobility group box 1 protein (HMGB1): Nuclear weapon in the immune arsenal
-
Lotze MT, Tracey KJ. High-mobility group box 1 protein (HMGB1): Nuclear weapon in the immune arsenal. Nat Rev Immunol 2005; 5: 331-342.
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 331-342
-
-
Lotze, M.T.1
Tracey, K.J.2
-
34
-
-
84874263775
-
Necroptosis: The release of damageassociated molecular patterns and its physiological relevance
-
Kaczmarek A, Vandenabeele P, Krysko DV. Necroptosis: The release of damageassociated molecular patterns and its physiological relevance. Immunity 2013; 38: 209-223.
-
(2013)
Immunity
, vol.38
, pp. 209-223
-
-
Kaczmarek, A.1
Vandenabeele, P.2
Krysko, D.V.3
-
35
-
-
84865758011
-
Programmed necrosis in acute kidney injury
-
Linkermann A, De Zen F, Weinberg J, Kunzendorf U, Krautwald S. Programmed necrosis in acute kidney injury. Nephrol Dial Transplant 2012; 27: 3412-3419.
-
(2012)
Nephrol Dial Transplant
, vol.27
, pp. 3412-3419
-
-
Linkermann, A.1
De Zen, F.2
Weinberg, J.3
Kunzendorf, U.4
Krautwald, S.5
-
36
-
-
84866151892
-
Programmed necrosis: A prominent mechanism of cell death following neonatal brain injury
-
Chavez-Valdez R, Martin LJ, Northington FJ. Programmed necrosis: A prominent mechanism of cell death following neonatal brain injury. Neurol Res Int 2012; 2012: 257563.
-
(2012)
Neurol Res Int
, vol.2012
, pp. 257563
-
-
Chavez-Valdez, R.1
Martin, L.J.2
Northington, F.J.3
-
37
-
-
78650911946
-
Necrostatin decreases oxidative damage, inflammation, and injury after neonatal HI
-
Northington FJ, Chavez-Valdez R, Graham EM, Razdan S, Gauda EB, Martin LJ. Necrostatin decreases oxidative damage, inflammation, and injury after neonatal HI. J Cereb Blood Flow Metab 2011; 31: 178-189.
-
(2011)
J Cereb Blood Flow Metab
, vol.31
, pp. 178-189
-
-
Northington, F.J.1
Chavez-Valdez, R.2
Graham, E.M.3
Razdan, S.4
Gauda, E.B.5
Martin, L.J.6
-
38
-
-
33644840693
-
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury
-
Degterev A, Huang Z, Boyce M, Li Y, Jagtap P, Mizushima N et al. Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat Chem Biol 2005; 1: 112-119.
-
(2005)
Nat Chem Biol
, vol.1
, pp. 112-119
-
-
Degterev, A.1
Huang, Z.2
Boyce, M.3
Li, Y.4
Jagtap, P.5
Mizushima, N.6
-
39
-
-
84892142596
-
The rodent endovascular puncture model of subarachnoid hemorrhage: Mechanisms of brain damage and therapeutic strategies
-
Kooijman E, Nijboer CH, van Velthoven CT, Kavelaars A, Kesecioglu J, Heijnen CJ. The rodent endovascular puncture model of subarachnoid hemorrhage: Mechanisms of brain damage and therapeutic strategies. J Neuroinflammation 2014; 11: 2.
-
(2014)
J Neuroinflammation
, vol.11
, pp. 2
-
-
Kooijman, E.1
Nijboer, C.H.2
Van Velthoven, C.T.3
Kavelaars, A.4
Kesecioglu, J.5
Heijnen, C.J.6
-
40
-
-
84897850099
-
Necrostatin-1 reduces neurovascular injury after intracerebral hemorrhage
-
King MD, Whitaker-Lea WA, Campbell JM, Alleyne Jr CH, Dhandapani KM. Necrostatin-1 reduces neurovascular injury after intracerebral hemorrhage. Int J Cell Biol 2014; 2014: 495817.
-
(2014)
Int J Cell Biol
, vol.2014
, pp. 495817
-
-
King, M.D.1
Whitaker-Lea, W.A.2
Campbell, J.M.3
Alleyne, C.H.4
Dhandapani, K.M.5
-
41
-
-
84895508213
-
Necroptosis drives motor neuron death in models of both sporadic and familial ALS
-
Re DB, Le Verche V, Yu C, Amoroso MW, Politi KA, Phani S et al. Necroptosis drives motor neuron death in models of both sporadic and familial ALS. Neuron 2014; 81: 1001-1008.
-
(2014)
Neuron
, vol.81
, pp. 1001-1008
-
-
Re, D.B.1
Le Verche, V.2
Yu, C.3
Amoroso, M.W.4
Politi, K.A.5
Phani, S.6
-
42
-
-
36248933743
-
Necrostatin-1 protects against glutamate-induced glutathione depletion and caspase-independent cell death in HT-22 cells
-
Xu X, Chua CC, Kong J, Kostrzewa RM, Kumaraguru U, Hamdy RC et al. Necrostatin-1 protects against glutamate-induced glutathione depletion and caspase-independent cell death in HT-22 cells. J Neurochem 2007; 103: 2004-2014.
-
(2007)
J Neurochem
, vol.103
, pp. 2004-2014
-
-
Xu, X.1
Chua, C.C.2
Kong, J.3
Kostrzewa, R.M.4
Kumaraguru, U.5
Hamdy, R.C.6
-
43
-
-
84954358195
-
Necroptosis contributes to the NMDA-induced excitotoxicity in rat's cultured cortical neurons
-
Li Y, Yang X, Ma C, Qiao J, Zhang C. Necroptosis contributes to the NMDA-induced excitotoxicity in rat's cultured cortical neurons. Neurosci Lett 2008; 447: 120-123.
-
(2008)
Neurosci Lett
, vol.447
, pp. 120-123
-
-
Li, Y.1
Yang, X.2
Ma, C.3
Qiao, J.4
Zhang, C.5
-
44
-
-
79960111702
-
24(S)-hydroxycholesterol induces neuronal cell death through necroptosis, a form of programmed necrosis
-
Yamanaka K, Saito Y, Yamamori T, Urano Y, Noguchi N. 24(S)-hydroxycholesterol induces neuronal cell death through necroptosis, a form of programmed necrosis. J Biol Chem 2011; 286: 24666-24673.
-
(2011)
J Biol Chem
, vol.286
, pp. 24666-24673
-
-
Yamanaka, K.1
Saito, Y.2
Yamamori, T.3
Urano, Y.4
Noguchi, N.5
-
45
-
-
0034904940
-
Neurotoxicity of 24-hydroxycholesterol, an important cholesterol elimination product of the brain, may be prevented by Vitamin E and estradiol-17beta
-
Kolsch H, Ludwig M, Lutjohann D, Rao ML. Neurotoxicity of 24-hydroxycholesterol, an important cholesterol elimination product of the brain, may be prevented by vitamin E and estradiol-17beta. J Neural Transm 2001; 108: 475-488.
-
(2001)
J Neural Transm
, vol.108
, pp. 475-488
-
-
Kolsch, H.1
Ludwig, M.2
Lutjohann, D.3
Rao, M.L.4
-
46
-
-
84861501372
-
Markers of cholesterol metabolism in the brain show stronger associations with cerebrovascular disease than Alzheimer's disease
-
Hughes TM, Kuller LH, Lopez OL, Becker JT, Evans RW, Sutton-Tyrrell K et al. Markers of cholesterol metabolism in the brain show stronger associations with cerebrovascular disease than Alzheimer's disease. J Alzheimers Dis 2012; 30: 53-61.
-
(2012)
J Alzheimers Dis
, vol.30
, pp. 53-61
-
-
Hughes, T.M.1
Kuller, L.H.2
Lopez, O.L.3
Becker, J.T.4
Evans, R.W.5
Sutton-Tyrrell, K.6
-
47
-
-
84891771031
-
Induction of apoptosis and necroptosis by 24(S)-hydroxycholesterol is dependent on activity of acyl-CoA: Cholesterol acyltransferase 1
-
Yamanaka K, Urano Y, Takabe W, Saito Y, Noguchi N. Induction of apoptosis and necroptosis by 24(S)-hydroxycholesterol is dependent on activity of acyl-CoA: Cholesterol acyltransferase 1. Cell Death Dis 2014; 5: E990.
-
(2014)
Cell Death Dis
, vol.5
, pp. e990
-
-
Yamanaka, K.1
Urano, Y.2
Takabe, W.3
Saito, Y.4
Noguchi, N.5
-
48
-
-
84871028547
-
CIAP1 and cIAP2 limit macrophage necroptosis by inhibiting Rip1 and Rip3 activation
-
McComb S, Cheung HH, Korneluk RG, Wang S, Krishnan L, Sad S. cIAP1 and cIAP2 limit macrophage necroptosis by inhibiting Rip1 and Rip3 activation. Cell Death Differ 2012; 19: 1791-1801.
-
(2012)
Cell Death Differ
, vol.19
, pp. 1791-1801
-
-
McComb, S.1
Cheung, H.H.2
Korneluk, R.G.3
Wang, S.4
Krishnan, L.5
Sad, S.6
-
49
-
-
84892608467
-
Cellular inhibitor of apoptosis protein cIAP2 protects against pulmonary tissue necrosis during influenza virus infection to promote host survival
-
Rodrigue-Gervais IG, Labbe K, Dagenais M, Dupaul-Chicoine J, Champagne C, Morizot A et al. Cellular inhibitor of apoptosis protein cIAP2 protects against pulmonary tissue necrosis during influenza virus infection to promote host survival. Cell Host Microbe 2014; 15: 23-35.
-
(2014)
Cell Host Microbe
, vol.15
, pp. 23-35
-
-
Rodrigue-Gervais, I.G.1
Labbe, K.2
Dagenais, M.3
Dupaul-Chicoine, J.4
Champagne, C.5
Morizot, A.6
-
50
-
-
84921284050
-
Liver-resident macrophage necroptosis orchestrates type 1 microbicidal inflammation and type-2-mediated tissue repair during bacterial infection
-
Bleriot C, Dupuis T, Jouvion G, Eberl G, Disson O, Lecuit M. Liver-resident macrophage necroptosis orchestrates type 1 microbicidal inflammation and type-2-mediated tissue repair during bacterial infection. Immunity 2015; 42: 145-158.
-
(2015)
Immunity
, vol.42
, pp. 145-158
-
-
Bleriot, C.1
Dupuis, T.2
Jouvion, G.3
Eberl, G.4
Disson, O.5
Lecuit, M.6
-
51
-
-
84887896349
-
Ultrastructural pathology of rat lung injury induced by ischemic acute kidney injury
-
Zang D, Shao Y, Li X. Ultrastructural pathology of rat lung injury induced by ischemic acute kidney injury. Ultrastruct Pathol 2013; 37: 433-439.
-
(2013)
Ultrastruct Pathol
, vol.37
, pp. 433-439
-
-
Zang, D.1
Shao, Y.2
Li, X.3
-
52
-
-
84926469754
-
Necroptosis and parthanatos are involved in remote lung injury after receiving ischemic renal allografts in rats
-
Zhao H, Ning J, Lemaire A, Koumpa FS, Sun JJ, Fung A et al. Necroptosis and parthanatos are involved in remote lung injury after receiving ischemic renal allografts in rats. Kidney Int 2014; 87: 738-748.
-
(2014)
Kidney Int
, vol.87
, pp. 738-748
-
-
Zhao, H.1
Ning, J.2
Lemaire, A.3
Koumpa, F.S.4
Sun, J.J.5
Fung, A.6
-
53
-
-
84907010947
-
Mitophagydependent necroptosis contributes to the pathogenesis of COPD
-
Mizumura K, Cloonan SM, Nakahira K, Bhashyam AR, Cervo M, Kitada T et al. Mitophagydependent necroptosis contributes to the pathogenesis of COPD. J Clin Invest 2014; 124: 3987-4003.
-
(2014)
J Clin Invest
, vol.124
, pp. 3987-4003
-
-
Mizumura, K.1
Cloonan, S.M.2
Nakahira, K.3
Bhashyam, A.R.4
Cervo, M.5
Kitada, T.6
-
54
-
-
84888438277
-
Widespread mitochondrial depletion via mitophagy does not compromise necroptosis
-
Tait SW, Oberst A, Quarato G, Milasta S, Haller M, Wang R et al. Widespread mitochondrial depletion via mitophagy does not compromise necroptosis. Cell Rep 2013; 5: 878-885.
-
(2013)
Cell Rep
, vol.5
, pp. 878-885
-
-
Tait, S.W.1
Oberst, A.2
Quarato, G.3
Milasta, S.4
Haller, M.5
Wang, R.6
-
55
-
-
84916211940
-
Red blood cells induce necroptosis of lung endothelial cells and increase susceptibility to lung inflammation
-
Qing DY, Conegliano D, Shashaty MG, Seo J, Reilly JP, Worthen GS et al. Red blood cells induce necroptosis of lung endothelial cells and increase susceptibility to lung inflammation. Am J Respir Crit Care Med 2014; 190: 1243-1254.
-
(2014)
Am J Respir Crit Care Med
, vol.190
, pp. 1243-1254
-
-
Qing, D.Y.1
Conegliano, D.2
Shashaty, M.G.3
Seo, J.4
Reilly, J.P.5
Worthen, G.S.6
-
56
-
-
84946094907
-
A role for tubular necroptosis in cisplatin-induced AKI
-
e-pub ahead of print 18 March 2015
-
Xu Y, Ma H, Shao J, Wu J, Zhou L, Zhang Z et al. A Role for Tubular Necroptosis in Cisplatin-Induced AKI. J Am Soc Nephrol 2015; e-pub ahead of print 18 March 2015.
-
(2015)
J Am Soc Nephrol
-
-
Xu, Y.1
Ma, H.2
Shao, J.3
Wu, J.4
Zhou, L.5
Zhang, Z.6
-
57
-
-
84857580777
-
Nec-1 protects against nonapoptotic cell death in cisplatin-induced kidney injury
-
Tristao VR, Goncalves PF, Dalboni MA, Batista MC, Durao Mde S Jr., Monte JC. Nec-1 protects against nonapoptotic cell death in cisplatin-induced kidney injury. Ren Fail 2012; 34: 373-377.
-
(2012)
Ren Fail
, vol.34
, pp. 373-377
-
-
Tristao, V.R.1
Goncalves, P.F.2
Dalboni, M.A.3
Batista, M.C.4
Durao Mde, S.5
Monte, J.C.6
-
58
-
-
84913582286
-
Synchronized renal tubular cell death involves ferroptosis
-
Linkermann A, Skouta R, Himmerkus N, Mulay SR, Dewitz C, De Zen F et al. Synchronized renal tubular cell death involves ferroptosis. Proc Natl Acad Sci USA 2014; 111: 16836-16841.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 16836-16841
-
-
Linkermann, A.1
Skouta, R.2
Himmerkus, N.3
Mulay, S.R.4
Dewitz, C.5
De Zen, F.6
-
59
-
-
84913594747
-
Regulated cell death in AKI
-
Linkermann A, Chen G, Dong G, Kunzendorf U, Krautwald S, Dong Z. Regulated cell death in AKI. J Am Soc Nephrol 2014; 25: 2689-2701.
-
(2014)
J Am Soc Nephrol
, vol.25
, pp. 2689-2701
-
-
Linkermann, A.1
Chen, G.2
Dong, G.3
Kunzendorf, U.4
Krautwald, S.5
Dong, Z.6
-
60
-
-
34548564715
-
Necrostatin: A potentially novel cardioprotective agent?
-
Smith CC, Davidson SM, Lim SY, Simpkin JC, Hothersall JS, Yellon DM. Necrostatin: A potentially novel cardioprotective agent? Cardiovasc Drugs Ther 2007; 21: 227-233.
-
(2007)
Cardiovasc Drugs Ther
, vol.21
, pp. 227-233
-
-
Smith, C.C.1
Davidson, S.M.2
Lim, S.Y.3
Simpkin, J.C.4
Hothersall, J.S.5
Yellon, D.M.6
-
61
-
-
84899576786
-
Combination of necroptosis and apoptosis inhibition enhances cardioprotection against myocardial ischemiareperfusion injury
-
Koshinuma S, Miyamae M, Kaneda K, Kotani J, Figueredo VM. Combination of necroptosis and apoptosis inhibition enhances cardioprotection against myocardial ischemiareperfusion injury. J Anesth 2014; 28: 235-241.
-
(2014)
J Anesth
, vol.28
, pp. 235-241
-
-
Koshinuma, S.1
Miyamae, M.2
Kaneda, K.3
Kotani, J.4
Figueredo, V.M.5
-
62
-
-
84860584135
-
Inhibition of RIP1-dependent necrosis prevents adverse cardiac remodeling after myocardial ischemia-reperfusion in vivo
-
Oerlemans MI, Liu J, Arslan F, den Ouden K, van Middelaar BJ, Doevendans PA et al. Inhibition of RIP1-dependent necrosis prevents adverse cardiac remodeling after myocardial ischemia-reperfusion in vivo. Basic Res Cardiol 2012; 107: 270.
-
(2012)
Basic Res Cardiol
, vol.107
, pp. 270
-
-
Oerlemans, M.I.1
Liu, J.2
Arslan, F.3
Den Ouden, K.4
Van Middelaar, B.J.5
Doevendans, P.A.6
-
63
-
-
84873152891
-
A role of RIP3-mediated macrophage necrosis in atherosclerosis development
-
Lin J, Li H, Yang M, Ren J, Huang Z, Han F et al. A role of RIP3-mediated macrophage necrosis in atherosclerosis development. Cell Rep 2013; 3: 200-210.
-
(2013)
Cell Rep
, vol.3
, pp. 200-210
-
-
Lin, J.1
Li, H.2
Yang, M.3
Ren, J.4
Huang, Z.5
Han, F.6
-
64
-
-
84907210946
-
RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis
-
Dannappel M, Vlantis K, Kumari S, Polykratis A, Kim C, Wachsmuth L et al. RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis. Nature 2014; 513: 90-94.
-
(2014)
Nature
, vol.513
, pp. 90-94
-
-
Dannappel, M.1
Vlantis, K.2
Kumari, S.3
Polykratis, A.4
Kim, C.5
Wachsmuth, L.6
-
65
-
-
84893726744
-
Necroptosis is active in children with inflammatory bowel disease and contributes to heighten intestinal inflammation
-
Pierdomenico M, Negroni A, Stronati L, Vitali R, Prete E, Bertin J et al. Necroptosis is active in children with inflammatory bowel disease and contributes to heighten intestinal inflammation. Am J Gastroenterol 2014; 109: 279-287.
-
(2014)
Am J Gastroenterol
, vol.109
, pp. 279-287
-
-
Pierdomenico, M.1
Negroni, A.2
Stronati, L.3
Vitali, R.4
Prete, E.5
Bertin, J.6
-
67
-
-
0037018761
-
Maintenance infliximab for Crohn's disease: The ACCENT I randomised trial
-
Hanauer SB, Feagan BG, Lichtenstein GR, Mayer LF, Schreiber S, Colombel JF et al. Maintenance infliximab for Crohn's disease: The ACCENT I randomised trial. Lancet 2002; 359: 1541-1549.
-
(2002)
Lancet
, vol.359
, pp. 1541-1549
-
-
Hanauer, S.B.1
Feagan, B.G.2
Lichtenstein, G.R.3
Mayer, L.F.4
Schreiber, S.5
Colombel, J.F.6
-
68
-
-
80052845560
-
Caspase-8 regulates TNF-αlpha-induced epithelial necroptosis and terminal ileitis
-
Gunther C, Martini E, Wittkopf N, Amann K, Weigmann B, Neumann H et al. Caspase-8 regulates TNF-αlpha-induced epithelial necroptosis and terminal ileitis. Nature 2011; 477: 335-339.
-
(2011)
Nature
, vol.477
, pp. 335-339
-
-
Gunther, C.1
Martini, E.2
Wittkopf, N.3
Amann, K.4
Weigmann, B.5
Neumann, H.6
-
69
-
-
84863784919
-
Inhibition of apoptosis protects mice from ethanol-mediated acceleration of early markers of CCl4-induced fibrosis but not steatosis or inflammation
-
Roychowdhury S, Chiang DJ, Mandal P, McMullen MR, Liu X, Cohen JI et al. Inhibition of apoptosis protects mice from ethanol-mediated acceleration of early markers of CCl4-induced fibrosis but not steatosis or inflammation. Alcohol Clin Exp Res 2012; 36: 1139-1147.
-
(2012)
Alcohol Clin Exp Res
, vol.36
, pp. 1139-1147
-
-
Roychowdhury, S.1
Chiang, D.J.2
Mandal, P.3
McMullen, M.R.4
Liu, X.5
Cohen, J.I.6
-
70
-
-
84905239992
-
A positive feedback loop between RIP3 and JNK controls non-alcoholic steatohepatitis
-
Gautheron J, Vucur M, Reisinger F, Cardenas DV, Roderburg C, Koppe C et al. A positive feedback loop between RIP3 and JNK controls non-alcoholic steatohepatitis. EMBO Mol Med 2014; 6: 1062-1074.
-
(2014)
EMBO Mol Med
, vol.6
, pp. 1062-1074
-
-
Gautheron, J.1
Vucur, M.2
Reisinger, F.3
Cardenas, D.V.4
Roderburg, C.5
Koppe, C.6
-
71
-
-
84919465499
-
Cell death and cell death responses in liver disease: Mechanisms and clinical relevance
-
Luedde T, Kaplowitz N, Schwabe RF. Cell death and cell death responses in liver disease: Mechanisms and clinical relevance. Gastroenterology 2014; 147: 765-783 e764.
-
(2014)
Gastroenterology
, vol.147
, pp. 765-783e764
-
-
Luedde, T.1
Kaplowitz, N.2
Schwabe, R.F.3
-
72
-
-
84907751865
-
Necrostatin-1 protects against reactive oxygen species (ROS)-induced hepatotoxicity in acetaminopheninduced acute liver failure
-
Takemoto K, Hatano E, Iwaisako K, Takeiri M, Noma N, Ohmae S et al. Necrostatin-1 protects against reactive oxygen species (ROS)-induced hepatotoxicity in acetaminopheninduced acute liver failure. FEBS Open Bio 2014; 4: 777-787.
-
(2014)
FEBS Open Bio
, vol.4
, pp. 777-787
-
-
Takemoto, K.1
Hatano, E.2
Iwaisako, K.3
Takeiri, M.4
Noma, N.5
Ohmae, S.6
-
73
-
-
84946824966
-
Acetaminophen/paracetamol: A history of errors, failures and false decisions
-
Brune K, Renner B, Tiegs G. Acetaminophen/paracetamol: A history of errors, failures and false decisions. Eur J Pain 2014; 19: 953-965.
-
(2014)
Eur J Pain
, vol.19
, pp. 953-965
-
-
Brune, K.1
Renner, B.2
Tiegs, G.3
-
74
-
-
61849117309
-
Human basophils and eosinophils are the direct target leukocytes of the novel IL-1 family member IL-33
-
Pecaric-Petkovic T, Didichenko SA, Kaempfer S, Spiegl N, Dahinden CA. Human basophils and eosinophils are the direct target leukocytes of the novel IL-1 family member IL-33. Blood 2009; 113: 1526-1534.
-
(2009)
Blood
, vol.113
, pp. 1526-1534
-
-
Pecaric-Petkovic, T.1
Didichenko, S.A.2
Kaempfer, S.3
Spiegl, N.4
Dahinden, C.A.5
-
75
-
-
84907217921
-
Hepatitis C virus-induced hepatocyte cell death and protection by inhibition of apoptosis
-
Lim EJ, El Khobar K, Chin R, Earnest-Silveira L, Angus PW, Bock CT et al. Hepatitis C virus-induced hepatocyte cell death and protection by inhibition of apoptosis. J Gen Virol 2014; 95(Pt 10): 2204-2215.
-
(2014)
J Gen Virol
, vol.95
, pp. 2204-2215
-
-
Lim, E.J.1
El Khobar, K.2
Chin, R.3
Earnest-Silveira, L.4
Angus, P.W.5
Bock, C.T.6
-
76
-
-
84899019365
-
Hepatocyte necroptosis induced by ischemic acute kidney injury in rats
-
Bao C, Shao Y, Li X. Hepatocyte necroptosis induced by ischemic acute kidney injury in rats. Ultrastruct Pathol 2014; 38: 217-223.
-
(2014)
Ultrastruct Pathol
, vol.38
, pp. 217-223
-
-
Bao, C.1
Shao, Y.2
Li, X.3
-
77
-
-
66749183275
-
Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-αlpha
-
He S, Wang L, Miao L, Wang T, Du F, Zhao L et al. Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-αlpha. Cell 2009; 137: 1100-1111.
-
(2009)
Cell
, vol.137
, pp. 1100-1111
-
-
He, S.1
Wang, L.2
Miao, L.3
Wang, T.4
Du, F.5
Zhao, L.6
-
78
-
-
67650812332
-
RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis
-
Zhang DW, Shao J, Lin J, Zhang N, Lu BJ, Lin SC et al. RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. Science 2009; 325: 332-336.
-
(2009)
Science
, vol.325
, pp. 332-336
-
-
Zhang, D.W.1
Shao, J.2
Lin, J.3
Zhang, N.4
Lu, B.J.5
Lin, S.C.6
-
79
-
-
84862175306
-
Dichotomy between RIP1- and RIP3-mediated necroptosis in tumor necrosis factor-alphainduced shock
-
Linkermann A, Brasen JH, De Zen F, Weinlich R, Schwendener RA, Green DR et al. Dichotomy between RIP1- and RIP3-mediated necroptosis in tumor necrosis factor-alphainduced shock. Mol Med 2012; 18: 577-586.
-
(2012)
Mol Med
, vol.18
, pp. 577-586
-
-
Linkermann, A.1
Brasen, J.H.2
De Zen, F.3
Weinlich, R.4
Schwendener, R.A.5
Green, D.R.6
-
80
-
-
84881184694
-
Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis
-
Wu J, Huang Z, Ren J, Zhang Z, He P, Li Y et al. Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis. Cell Res 2013; 23: 994-1006.
-
(2013)
Cell Res
, vol.23
, pp. 994-1006
-
-
Wu, J.1
Huang, Z.2
Ren, J.3
Zhang, Z.4
He, P.5
Li, Y.6
-
81
-
-
84908128377
-
The necroptosis adaptor RIPK3 promotes injury-induced cytokine expression and tissue repair
-
Moriwaki K, Balaji S, McQuade T, Malhotra N, Kang J, Chan FK. The necroptosis adaptor RIPK3 promotes injury-induced cytokine expression and tissue repair. Immunity 2014; 41: 567-578.
-
(2014)
Immunity
, vol.41
, pp. 567-578
-
-
Moriwaki, K.1
Balaji, S.2
McQuade, T.3
Malhotra, N.4
Kang, J.5
Chan, F.K.6
-
82
-
-
42249102086
-
Identification of RIP1 kinase as a specific cellular target of necrostatins
-
Degterev A, Hitomi J, Germscheid M, Ch'en IL, Korkina O, Teng X et al. Identification of RIP1 kinase as a specific cellular target of necrostatins. Nat Chem Biol 2008; 4: 313-321.
-
(2008)
Nat Chem Biol
, vol.4
, pp. 313-321
-
-
Degterev, A.1
Hitomi, J.2
Germscheid, M.3
Chen, I.L.4
Korkina, O.5
Teng, X.6
-
83
-
-
84869024586
-
New components of the necroptotic pathway
-
Zhou Z, Han V, Han J. New components of the necroptotic pathway. Protein Cell 2012; 3: 811-817.
-
(2012)
Protein Cell
, vol.3
, pp. 811-817
-
-
Zhou, Z.1
Han, V.2
Han, J.3
-
84
-
-
78650718758
-
Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis
-
Trichonas G, Murakami Y, Thanos A, Morizane Y, Kayama M, Debouck CM et al. Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis. Proc Natl Acad Sci USA 2010; 107: 21695-21700.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 21695-21700
-
-
Trichonas, G.1
Murakami, Y.2
Thanos, A.3
Morizane, Y.4
Kayama, M.5
Debouck, C.M.6
-
85
-
-
76749109832
-
RIP1's function in NF-kappaB activation: From master actor to onlooker
-
Bertrand MJ, Vandenabeele P. RIP1's function in NF-kappaB activation: From master actor to onlooker. Cell Death Differ 2010; 17: 379-380.
-
(2010)
Cell Death Differ
, vol.17
, pp. 379-380
-
-
Bertrand, M.J.1
Vandenabeele, P.2
-
86
-
-
84870570760
-
Necrostatin-1 analogues: Critical issues on the specificity, activity and in vivo use in experimental disease models
-
Takahashi N, Duprez L, Grootjans S, Cauwels A, Nerinckx W, DuHadaway JB et al. Necrostatin-1 analogues: Critical issues on the specificity, activity and in vivo use in experimental disease models. Cell Death Dis 2012; 3: E437.
-
(2012)
Cell Death Dis
, vol.3
, pp. e437
-
-
Takahashi, N.1
Duprez, L.2
Grootjans, S.3
Cauwels, A.4
Nerinckx, W.5
DuHadaway, J.B.6
-
87
-
-
84886305117
-
Regulation of RIP1 kinase signalling at the crossroads of inflammation and cell death
-
Ofengeim D, Yuan J. Regulation of RIP1 kinase signalling at the crossroads of inflammation and cell death. Nat Rev Mol Cell Biol 2013; 14: 727-736.
-
(2013)
Nat Rev Mol Cell Biol
, vol.14
, pp. 727-736
-
-
Ofengeim, D.1
Yuan, J.2
-
88
-
-
84874860953
-
Structural basis of RIP1 inhibition by necrostatins
-
Xie T, Peng W, Liu Y, Yan C, Maki J, Degterev A et al. Structural basis of RIP1 inhibition by necrostatins. Structure 2013; 21: 493-499.
-
(2013)
Structure
, vol.21
, pp. 493-499
-
-
Xie, T.1
Peng, W.2
Liu, Y.3
Yan, C.4
Maki, J.5
Degterev, A.6
-
89
-
-
58749100879
-
Receptor-interacting protein homotypic interaction motif-dependent control of NF-kappa B activation via the DNA-dependent activator of IFN regulatory factors
-
Kaiser WJ, Upton JW, Mocarski ES. Receptor-interacting protein homotypic interaction motif-dependent control of NF-kappa B activation via the DNA-dependent activator of IFN regulatory factors. J Immunol 2008; 181: 6427-6434.
-
(2008)
J Immunol
, vol.181
, pp. 6427-6434
-
-
Kaiser, W.J.1
Upton, J.W.2
Mocarski, E.S.3
-
90
-
-
84872310440
-
Activity and specificity of necrostatin-1, small-molecule inhibitor of RIP1 kinase
-
Degterev A, Maki JL, Yuan J. Activity and specificity of necrostatin-1, small-molecule inhibitor of RIP1 kinase. Cell Death Differ 2013; 20: 366.
-
(2013)
Cell Death Differ
, vol.20
, pp. 366
-
-
Degterev, A.1
Maki, J.L.2
Yuan, J.3
-
91
-
-
84863486901
-
A novel role for RIP1 kinase in mediating TNFalpha production
-
Christofferson DE, Li Y, Hitomi J, Zhou W, Upperman C, Zhu H et al. A novel role for RIP1 kinase in mediating TNFalpha production. Cell Death Dis 2012; 3: E320.
-
(2012)
Cell Death Dis
, vol.3
, pp. e320
-
-
Christofferson, D.E.1
Li, Y.2
Hitomi, J.3
Zhou, W.4
Upperman, C.5
Zhu, H.6
-
92
-
-
84890534620
-
Discovery of small molecule RIP1 kinase inhibitors for the treatment of pathologies associated with necroptosis
-
Harris PA, Bandyopadhyay D, Berger SB, Campobasso N, Capriotti CA, Cox JA et al. Discovery of small molecule RIP1 kinase inhibitors for the treatment of pathologies associated with necroptosis. ACS Med Chem Lett 2013; 4: 1238-1243.
-
(2013)
ACS Med Chem Lett
, vol.4
, pp. 1238-1243
-
-
Harris, P.A.1
Bandyopadhyay, D.2
Berger, S.B.3
Campobasso, N.4
Capriotti, C.A.5
Cox, J.A.6
-
93
-
-
84901045151
-
Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death
-
Weng D, Marty-Roix R, Ganesan S, Proulx MK, Vladimer GI, Kaiser WJ et al. Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death. Proc Natl Acad Sci USA 2014; 111: 7391-7396.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 7391-7396
-
-
Weng, D.1
Marty-Roix, R.2
Ganesan, S.3
Proulx, M.K.4
Vladimer, G.I.5
Kaiser, W.J.6
-
94
-
-
84912106351
-
RIP3 induces apoptosis independent of pronecrotic kinase activity
-
Mandal P, Berger SB, Pillay S, Moriwaki K, Huang C, Guo H et al. RIP3 induces apoptosis independent of pronecrotic kinase activity. Mol Cell 2014; 56: 481-495.
-
(2014)
Mol Cell
, vol.56
, pp. 481-495
-
-
Mandal, P.1
Berger, S.B.2
Pillay, S.3
Moriwaki, K.4
Huang, C.5
Guo, H.6
-
95
-
-
84928128217
-
A cytosolic heat shock protein 90 and cochaperone CDC37 complex is required for RIP3 activation during necroptosis
-
Li D, Xu T, Cao Y, Wang H, Li L, Chen S et al. A cytosolic heat shock protein 90 and cochaperone CDC37 complex is required for RIP3 activation during necroptosis. Proc Natl Acad Sci USA 2015; 112: 5017-5022.
-
(2015)
Proc Natl Acad Sci USA
, vol.112
, pp. 5017-5022
-
-
Li, D.1
Xu, T.2
Cao, Y.3
Wang, H.4
Li, L.5
Chen, S.6
-
96
-
-
84884308522
-
The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism
-
Murphy JM, Czabotar PE, Hildebrand JM, Lucet IS, Zhang JG, Alvarez-Diaz S et al. The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism. Immunity 2013; 39: 443-453.
-
(2013)
Immunity
, vol.39
, pp. 443-453
-
-
Murphy, J.M.1
Czabotar, P.E.2
Hildebrand, J.M.3
Lucet, I.S.4
Zhang, J.G.5
Alvarez-Diaz, S.6
-
97
-
-
84922394053
-
Regulated cell death and inflammation: An auto-amplification loop causes organ failure
-
Linkermann A, Stockwell BR, Krautwald S, Anders HJ. Regulated cell death and inflammation: An auto-amplification loop causes organ failure. Nat Rev Immunol 2014; 14: 759-767.
-
(2014)
Nat Rev Immunol
, vol.14
, pp. 759-767
-
-
Linkermann, A.1
Stockwell, B.R.2
Krautwald, S.3
Anders, H.J.4
-
98
-
-
84894550453
-
Regulated necrosis: The expanding network of non-apoptotic cell death pathways
-
Vanden Berghe T, Linkermann A, Jouan-Lanhouet S, Walczak H, Vandenabeele P. Regulated necrosis: The expanding network of non-apoptotic cell death pathways. Nat Rev Mol Cell Biol 2014; 15: 135-147.
-
(2014)
Nat Rev Mol Cell Biol
, vol.15
, pp. 135-147
-
-
Vanden Berghe, T.1
Linkermann, A.2
Jouan-Lanhouet, S.3
Walczak, H.4
Vandenabeele, P.5
-
99
-
-
77952236200
-
Necroptosis, necrosis and secondary necrosis converge on similar cellular disintegration features
-
Vanden Berghe T, Vanlangenakker N, Parthoens E, Deckers W, Devos M, Festjens N et al. Necroptosis, necrosis and secondary necrosis converge on similar cellular disintegration features. Cell Death Differ 2010; 17: 922-930.
-
(2010)
Cell Death Differ
, vol.17
, pp. 922-930
-
-
Vanden Berghe, T.1
Vanlangenakker, N.2
Parthoens, E.3
Deckers, W.4
Devos, M.5
Festjens, N.6
-
100
-
-
84935699564
-
Necroptosis suppresses inflammation via termination of TNF- or LPS-induced cytokine and chemokine production
-
Kearney CJ, Cullen SP, Tynan GA, Henry CM, Clancy D, Lavelle EC et al. Necroptosis suppresses inflammation via termination of TNF- or LPS-induced cytokine and chemokine production. Cell Death Differ 2015; 22: 1313-1327.
-
(2015)
Cell Death Differ
, vol.22
, pp. 1313-1327
-
-
Kearney, C.J.1
Cullen, S.P.2
Tynan, G.A.3
Henry, C.M.4
Clancy, D.5
Lavelle, E.C.6
-
101
-
-
84881375174
-
Xenon treatment protects against cold ischemia associated delayed graft function and prolongs graft survival in rats
-
Zhao H, Watts HR, Chong M, Huang H, Tralau-Stewart C, Maxwell PH et al. Xenon treatment protects against cold ischemia associated delayed graft function and prolongs graft survival in rats. Am J Transplant 2013; 13: 2006-2018.
-
(2013)
Am J Transplant
, vol.13
, pp. 2006-2018
-
-
Zhao, H.1
Watts, H.R.2
Chong, M.3
Huang, H.4
Tralau-Stewart, C.5
Maxwell, P.H.6
-
103
-
-
84864849535
-
Histones from dying renal cells aggravate kidney injury via TLR2 and TLR4
-
Allam R, Scherbaum CR, Darisipudi MN, Mulay SR, Hagele H, Lichtnekert J et al. Histones from dying renal cells aggravate kidney injury via TLR2 and TLR4. J Am Soc Nephrol 2012; 23: 1375-1388.
-
(2012)
J Am Soc Nephrol
, vol.23
, pp. 1375-1388
-
-
Allam, R.1
Scherbaum, C.R.2
Darisipudi, M.N.3
Mulay, S.R.4
Hagele, H.5
Lichtnekert, J.6
-
104
-
-
84872555329
-
Circulating histones are mediators of trauma-associated lung injury
-
Abrams ST, Zhang N, Manson J, Liu T, Dart C, Baluwa F et al. Circulating histones are mediators of trauma-associated lung injury. Am J Respir Crit Care Med 2013; 187: 160-169.
-
(2013)
Am J Respir Crit Care Med
, vol.187
, pp. 160-169
-
-
Abrams, S.T.1
Zhang, N.2
Manson, J.3
Liu, T.4
Dart, C.5
Baluwa, F.6
-
105
-
-
84920439936
-
The P2X1 receptor is required for neutrophil extravasation during lipopolysaccharide-induced lethal endotoxemia in mice
-
Maitre B, Magnenat S, Heim V, Ravanat C, Evans RJ, de la Salle H et al. The P2X1 receptor is required for neutrophil extravasation during lipopolysaccharide-induced lethal endotoxemia in mice. J Immunol 2015; 194: 739-749.
-
(2015)
J Immunol
, vol.194
, pp. 739-749
-
-
Maitre, B.1
Magnenat, S.2
Heim, V.3
Ravanat, C.4
Evans, R.J.5
De La Salle, H.6
-
106
-
-
84902187683
-
Deletion of CD24 impairs development of heat shock protein gp96-driven autoimmune disease through expansion of myeloid-derived suppressor cells
-
Thaxton JE, Liu B, Zheng P, Liu Y, Li Z. Deletion of CD24 impairs development of heat shock protein gp96-driven autoimmune disease through expansion of myeloid-derived suppressor cells. J Immunol 2014; 192: 5679-5686.
-
(2014)
J Immunol
, vol.192
, pp. 5679-5686
-
-
Thaxton, J.E.1
Liu, B.2
Zheng, P.3
Liu, Y.4
Li, Z.5
-
107
-
-
84900525694
-
Role of Toll-like receptor-4 in renal graft ischemia-reperfusion injury
-
Zhao H, Perez JS, Lu K, George AJ, Ma D. Role of Toll-like receptor-4 in renal graft ischemia-reperfusion injury. Am J Physiol Renal Physiol 2014; 306: F801-F811.
-
(2014)
Am J Physiol Renal Physiol
, vol.306
, pp. F801-F811
-
-
Zhao, H.1
Perez, J.S.2
Lu, K.3
George, A.J.4
Ma, D.5
-
108
-
-
84930829907
-
Mitochondrial DNA damage-associated molecular patterns mediate a feed-forward cycle of bacteriainduced vascular injury in perfused rat lungs
-
Kuck JL, Obiako BO, Gorodnya OM, Pastukh VM, Kua J, Simmons JD et al. Mitochondrial DNA damage-associated molecular patterns mediate a feed-forward cycle of bacteriainduced vascular injury in perfused rat lungs. Am J Physiol Lung Cell Mol Physiol 2015; 308: L1078-L1085.
-
(2015)
Am J Physiol Lung Cell Mol Physiol
, vol.308
, pp. L1078-L1085
-
-
Kuck, J.L.1
Obiako, B.O.2
Gorodnya, O.M.3
Pastukh, V.M.4
Kua, J.5
Simmons, J.D.6
-
109
-
-
79952339508
-
Dangers within: DAMP responses to damage and cell death in kidney disease
-
Rosin DL, Okusa MD. Dangers within: DAMP responses to damage and cell death in kidney disease. J Am Soc Nephrol 2011; 22: 416-425.
-
(2011)
J Am Soc Nephrol
, vol.22
, pp. 416-425
-
-
Rosin, D.L.1
Okusa, M.D.2
-
110
-
-
65149097030
-
Interleukin-33 - cytokine of dual function or novel alarmin?
-
Haraldsen G, Balogh J, Pollheimer J, Sponheim J, Kuchler AM. Interleukin-33 - cytokine of dual function or novel alarmin? Trends Immunol 2009; 30: 227-233.
-
(2009)
Trends Immunol
, vol.30
, pp. 227-233
-
-
Haraldsen, G.1
Balogh, J.2
Pollheimer, J.3
Sponheim, J.4
Kuchler, A.M.5
-
111
-
-
80053075831
-
Cyclophilin A is a damage-associated molecular pattern molecule that mediates acetaminophen-induced liver injury
-
Dear JW, Simpson KJ, Nicolai MP, Catterson JH, Street J, Huizinga T et al. Cyclophilin A is a damage-associated molecular pattern molecule that mediates acetaminophen-induced liver injury. J Immunol 2011; 187: 3347-3352.
-
(2011)
J Immunol
, vol.187
, pp. 3347-3352
-
-
Dear, J.W.1
Simpson, K.J.2
Nicolai, M.P.3
Catterson, J.H.4
Street, J.5
Huizinga, T.6
-
112
-
-
78349309166
-
Cyclophilin A release as a biomarker of necrotic cell death
-
Christofferson DE, Yuan J. Cyclophilin A release as a biomarker of necrotic cell death. Cell Death Differ 2010; 17: 1942-1943.
-
(2010)
Cell Death Differ
, vol.17
, pp. 1942-1943
-
-
Christofferson, D.E.1
Yuan, J.2
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