-
1
-
-
0036852215
-
To kill or be killed: viral evasion of apoptosis
-
Benedict, C. A., Norris, P. S., and Ware, C. F. (2002). To kill or be killed: viral evasion of apoptosis. Nat Immunol 3, 1013-1018.
-
(2002)
Nat Immunol
, vol.3
, pp. 1013-1018
-
-
Benedict, C.A.1
Norris, P.S.2
Ware, C.F.3
-
2
-
-
44949240664
-
cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination
-
Bertrand, M. J., Milutinovic, S., Dickson, K. M., Ho, W. C., Boudreault, A., Durkin, J., Gillard, J. W., Jaquith, J. B., Morris, S. J., and Barker, P. A. (2008). cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination. Mol Cell 30, 689-700.
-
(2008)
Mol Cell
, vol.30
, pp. 689-700
-
-
Bertrand, M.J.1
Milutinovic, S.2
Dickson, K.M.3
Ho, W.C.4
Boudreault, A.5
Durkin, J.6
Gillard, J.W.7
Jaquith, J.B.8
Morris, S.J.9
Barker, P.A.10
-
3
-
-
80755132824
-
The adaptor protein FADD protects epidermal keratinocytes from necroptosis in vivo and prevents skin inflammation
-
Bonnet, M. C., Preukschat, D., Welz, P. S., van Loo, G., Ermolaeva, M. A., Bloch, W., Haase, I., and Pasparakis, M. (2011). The adaptor protein FADD protects epidermal keratinocytes from necroptosis in vivo and prevents skin inflammation. Immunity 35, 572-582.
-
(2011)
Immunity
, vol.35
, pp. 572-582
-
-
Bonnet, M.C.1
Preukschat, D.2
Welz, P.S.3
van Loo, G.4
Ermolaeva, M.A.5
Bloch, W.6
Haase, I.7
Pasparakis, M.8
-
4
-
-
34547442346
-
Bak regulates mitochondrial morphology and pathology during apoptosis by interacting with mitofusins
-
Brooks, C., Wei, Q., Feng, L., Dong, G., Tao, Y., Mei, L., Xie, Z. J., and Dong, Z. (2007). Bak regulates mitochondrial morphology and pathology during apoptosis by interacting with mitofusins. Proc Natl Acad Sci U S A 104, 11649-11654.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 11649-11654
-
-
Brooks, C.1
Wei, Q.2
Feng, L.3
Dong, G.4
Tao, Y.5
Mei, L.6
Xie, Z.J.7
Dong, Z.8
-
5
-
-
79955484750
-
Mechanisms of necroptosis in T cells
-
Ch'en, I. L., Tsau, J. S., Molkentin, J. D., Komatsu, M., and Hedrick, S. M. (2011). Mechanisms of necroptosis in T cells. J Exp Med 208, 633-641.
-
(2011)
J Exp Med
, vol.208
, pp. 633-641
-
-
Ch'en, I.L.1
Tsau, J.S.2
Molkentin, J.D.3
Komatsu, M.4
Hedrick, S.M.5
-
6
-
-
66449133280
-
Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation
-
Cho, Y. S., Challa, S., Moquin, D., Genga, R., Ray, T. D., Guildford, M., and Chan, F. K. (2009). Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation. Cell 137, 1112-1123.
-
(2009)
Cell
, vol.137
, pp. 1112-1123
-
-
Cho, Y.S.1
Challa, S.2
Moquin, D.3
Genga, R.4
Ray, T.D.5
Guildford, M.6
Chan, F.K.7
-
7
-
-
42249102086
-
Identification of RIP1 kinase as a specific cellular target of necrostatins
-
Degterev, A., Hitomi, J., Germscheid, M., Ch'en, I. L., Korkina, O., Teng, X., Abbott, D., Cuny, G. D., Yuan, C., Wagner, G., et al. (2008). Identification of RIP1 kinase as a specific cellular target of necrostatins. Nat Chem Biol 4, 313-321.
-
(2008)
Nat Chem Biol
, vol.4
, pp. 313-321
-
-
Degterev, A.1
Hitomi, J.2
Germscheid, M.3
Ch'en, I.L.4
Korkina, O.5
Teng, X.6
Abbott, D.7
Cuny, G.D.8
Yuan, C.9
Wagner, G.10
-
8
-
-
33644840693
-
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury
-
Degterev, A., Huang, Z., Boyce, M., Li, Y., Jagtap, P., Mizushima, N., Cuny, G. D., Mitchison, T. J., Moskowitz, M. A., and Yuan, J. (2005). Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat Chem Biol 1, 112-119.
-
(2005)
Nat Chem Biol
, vol.1
, pp. 112-119
-
-
Degterev, A.1
Huang, Z.2
Boyce, M.3
Li, Y.4
Jagtap, P.5
Mizushima, N.6
Cuny, G.D.7
Mitchison, T.J.8
Moskowitz, M.A.9
Yuan, J.10
-
9
-
-
69449096248
-
Cyclophilin D gene ablation protects mice from ischemic renal injury
-
Devalaraja-Narashimha, K., Diener, A. M., and Padanilam, B. J. (2009). Cyclophilin D gene ablation protects mice from ischemic renal injury. Am J Physiol Renal Physiol 297, F749-759.
-
(2009)
Am J Physiol Renal Physiol
, vol.297
-
-
Devalaraja-Narashimha, K.1
Diener, A.M.2
Padanilam, B.J.3
-
10
-
-
33646034316
-
Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO
-
Ea, C. K., Deng, L., Xia, Z. P., Pineda, G., and Chen, Z. J. (2006). Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO. Mol Cell 22, 245-257.
-
(2006)
Mol Cell
, vol.22
, pp. 245-257
-
-
Ea, C.K.1
Deng, L.2
Xia, Z.P.3
Pineda, G.4
Chen, Z.J.5
-
11
-
-
34249019899
-
Inhibiting Drp1-mediated mitochondrial fission selectively prevents the release of cytochrome c during apoptosis
-
Estaquier, J., and Arnoult, D. (2007). Inhibiting Drp1-mediated mitochondrial fission selectively prevents the release of cytochrome c during apoptosis. Cell Death Differ 14, 1086-1094.
-
(2007)
Cell Death Differ
, vol.14
, pp. 1086-1094
-
-
Estaquier, J.1
Arnoult, D.2
-
12
-
-
79960922705
-
cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms
-
Feoktistova, M., Geserick, P., Kellert, B., Dimitrova, D. P., Langlais, C., Hupe, M., Cain, K., MacFarlane, M., Hacker, G., and Leverkus, M. (2011). cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms. Mol Cell 43, 449-463.
-
(2011)
Mol Cell
, vol.43
, pp. 449-463
-
-
Feoktistova, M.1
Geserick, P.2
Kellert, B.3
Dimitrova, D.P.4
Langlais, C.5
Hupe, M.6
Cain, K.7
MacFarlane, M.8
Hacker, G.9
Leverkus, M.10
-
13
-
-
84858017083
-
Heme induces programmed necrosis on macrophages through autocrine TNF and ROS production
-
Fortes, G. B., Alves, L. S., de Oliveira, R., Dutra, F. F., Rodrigues, D., Fernandez, P. L., Souto-Padron, T., De Rosa, M. J., Kelliher, M., Golenbock, D., et al. (2012). Heme induces programmed necrosis on macrophages through autocrine TNF and ROS production. Blood 119, 2368-2375.
-
(2012)
Blood
, vol.119
, pp. 2368-2375
-
-
Fortes, G.B.1
Alves, L.S.2
de Oliveira, R.3
Dutra, F.F.4
Rodrigues, D.5
Fernandez, P.L.6
Souto-Padron, T.7
de Rosa, M.J.8
Kelliher, M.9
Golenbock, D.10
-
14
-
-
0035487808
-
The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis
-
Frank, S., Gaume, B., Bergmann-Leitner, E. S., Leitner, W. W., Robert, E. G., Catez, F., Smith, C. L., and Youle, R. J. (2001). The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis. Dev Cell 1, 515-525.
-
(2001)
Dev Cell
, vol.1
, pp. 515-525
-
-
Frank, S.1
Gaume, B.2
Bergmann-Leitner, E.S.3
Leitner, W.W.4
Robert, E.G.5
Catez, F.6
Smith, C.L.7
Youle, R.J.8
-
15
-
-
80053642372
-
FADD: an endogenous inhibitor of RIP3-driven regulated necrosis
-
Galluzzi, L., Kepp, O., and Kroemer, G. (2011). FADD: an endogenous inhibitor of RIP3-driven regulated necrosis. Cell Res 21, 1383-1385.
-
(2011)
Cell Res
, vol.21
, pp. 1383-1385
-
-
Galluzzi, L.1
Kepp, O.2
Kroemer, G.3
-
16
-
-
84255210700
-
Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012
-
Galluzzi, L., Vitale, I., Abrams, J. M., Alnemri, E. S., Baehrecke, E. H., Blagosklonny, M. V., Dawson, T. M., Dawson, V. L., El-Deiry, W. S., Fulda, S., et al. (2012). Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012. Cell Death Differ 19, 107-120.
-
(2012)
Cell Death Differ
, vol.19
, pp. 107-120
-
-
Galluzzi, L.1
Vitale, I.2
Abrams, J.M.3
Alnemri, E.S.4
Baehrecke, E.H.5
Blagosklonny, M.V.6
Dawson, T.M.7
Dawson, V.L.8
El-Deiry, W.S.9
Fulda, S.10
-
17
-
-
18444400187
-
Endoplasmic reticulum BIK initiates DRP1-regulated remodelling of mitochondrial cristae during apoptosis
-
Germain, M., Mathai, J. P., McBride, H. M., and Shore, G. C. (2005). Endoplasmic reticulum BIK initiates DRP1-regulated remodelling of mitochondrial cristae during apoptosis. EMBO J 24, 1546-1556.
-
(2005)
EMBO J
, vol.24
, pp. 1546-1556
-
-
Germain, M.1
Mathai, J.P.2
McBride, H.M.3
Shore, G.C.4
-
18
-
-
80052845560
-
Caspase-8 regulates TNF-alpha-induced epithelial necroptosis and terminal ileitis
-
Gunther, C., Martini, E., Wittkopf, N., Amann, K., Weigmann, B., Neumann, H., Waldner, M. J., Hedrick, S. M., Tenzer, S., Neurath, M. F., et al. (2011). Caspase-8 regulates TNF-alpha-induced epithelial necroptosis and terminal ileitis. Nature 477, 335-339.
-
(2011)
Nature
, vol.477
, pp. 335-339
-
-
Gunther, C.1
Martini, E.2
Wittkopf, N.3
Amann, K.4
Weigmann, B.5
Neumann, H.6
Waldner, M.J.7
Hedrick, S.M.8
Tenzer, S.9
Neurath, M.F.10
-
19
-
-
71149105333
-
Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction
-
Haas, T. L., Emmerich, C. H., Gerlach, B., Schmukle, A. C., Cordier, S. M., Rieser, E., Feltham, R., Vince, J., Warnken, U., Wenger, T., et al. (2009). Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction. Mol Cell 36, 831-844.
-
(2009)
Mol Cell
, vol.36
, pp. 831-844
-
-
Haas, T.L.1
Emmerich, C.H.2
Gerlach, B.3
Schmukle, A.C.4
Cordier, S.M.5
Rieser, E.6
Feltham, R.7
Vince, J.8
Warnken, U.9
Wenger, T.10
-
20
-
-
81255195542
-
Programmed necrosis: backup to and competitor with apoptosis in the immune system
-
Han, J., Zhong, C. Q., and Zhang, D. W. (2011). Programmed necrosis: backup to and competitor with apoptosis in the immune system. Nat Immunol 12, 1143-1149.
-
(2011)
Nat Immunol
, vol.12
, pp. 1143-1149
-
-
Han, J.1
Zhong, C.Q.2
Zhang, D.W.3
-
21
-
-
67349269527
-
Necrostatin-1 reverts shikonin-induced necroptosis to apoptosis
-
Han, W., Xie, J., Li, L., Liu, Z., and Hu, X. (2009). Necrostatin-1 reverts shikonin-induced necroptosis to apoptosis. Apoptosis 14, 674-686.
-
(2009)
Apoptosis
, vol.14
, pp. 674-686
-
-
Han, W.1
Xie, J.2
Li, L.3
Liu, Z.4
Hu, X.5
-
22
-
-
0037815277
-
Fas-associated death domain protein and caspase-8 are not recruited to the tumor necrosis factor receptor 1 signaling complex during tumor necrosis factor-induced apoptosis
-
Harper, N., Hughes, M., MacFarlane, M., and Cohen, G. M. (2003). Fas-associated death domain protein and caspase-8 are not recruited to the tumor necrosis factor receptor 1 signaling complex during tumor necrosis factor-induced apoptosis. J Biol Chem 278, 25534-25541.
-
(2003)
J Biol Chem
, vol.278
, pp. 25534-25541
-
-
Harper, N.1
Hughes, M.2
MacFarlane, M.3
Cohen, G.M.4
-
23
-
-
66749183275
-
Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha
-
He, S., Wang, L., Miao, L., Wang, T., Du, F., Zhao, L., and Wang, X. (2009). Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha. Cell 137, 1100-1111.
-
(2009)
Cell
, vol.137
, pp. 1100-1111
-
-
He, S.1
Wang, L.2
Miao, L.3
Wang, T.4
Du, F.5
Zhao, L.6
Wang, X.7
-
24
-
-
5944233768
-
Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule
-
Holler, N., Zaru, R., Micheau, O., Thome, M., Attinger, A., Valitutti, S., Bodmer, J. L., Schneider, P., Seed, B., and Tschopp, J. (2000). Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule. Nat Immunol 1, 489-495.
-
(2000)
Nat Immunol
, vol.1
, pp. 489-495
-
-
Holler, N.1
Zaru, R.2
Micheau, O.3
Thome, M.4
Attinger, A.5
Valitutti, S.6
Bodmer, J.L.7
Schneider, P.8
Seed, B.9
Tschopp, J.10
-
25
-
-
80052583012
-
Requirement of FADD, NEMO, and BAX/BAK for aberrant mitochondrial function in tumor necrosis factor alpha-induced necrosis
-
Irrinki, K. M., Mallilankaraman, K., Thapa, R. J., Chandramoorthy, H. C., Smith, F. J., Jog, N. R., Gandhirajan, R. K., Kelsen, S. G., Houser, S. R., May, M. J., et al. (2011). Requirement of FADD, NEMO, and BAX/BAK for aberrant mitochondrial function in tumor necrosis factor alpha-induced necrosis. Mol Cell Biol 31, 3745-3758.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 3745-3758
-
-
Irrinki, K.M.1
Mallilankaraman, K.2
Thapa, R.J.3
Chandramoorthy, H.C.4
Smith, F.J.5
Jog, N.R.6
Gandhirajan, R.K.7
Kelsen, S.G.8
Houser, S.R.9
May, M.J.10
-
26
-
-
38949093002
-
TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines
-
Ishii, K. J., Kawagoe, T., Koyama, S., Matsui, K., Kumar, H., Kawai, T., Uematsu, S., Takeuchi, O., Takeshita, F., Coban, C., et al. (2008). TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines. Nature 451, 725-729.
-
(2008)
Nature
, vol.451
, pp. 725-729
-
-
Ishii, K.J.1
Kawagoe, T.2
Koyama, S.3
Matsui, K.4
Kumar, H.5
Kawai, T.6
Uematsu, S.7
Takeuchi, O.8
Takeshita, F.9
Coban, C.10
-
27
-
-
84869092484
-
TRAIL induces necroptosis involving RIPK1/RIPK3-dependent PARP-1 activation
-
(In Press)
-
Jouan-Lanhouet, S., Arshad, M. I., Piquet-Pellorce, C., Martin-Chouly, C., Le Moigne-Muller, G., van Herreweghe, F., Takahashi, N., Sergent, O., Lagadic-Gossmann, D., Vandenabeele, P., et al. (2012). TRAIL induces necroptosis involving RIPK1/RIPK3-dependent PARP-1 activation. Cell Death Differ. (In Press).
-
(2012)
Cell Death Differ
-
-
Jouan-Lanhouet, S.1
Arshad, M.I.2
Piquet-Pellorce, C.3
Martin-Chouly, C.4
Le Moigne-Muller, G.5
van Herreweghe, F.6
Takahashi, N.7
Sergent, O.8
Lagadic-Gossmann, D.9
Vandenabeele, P.10
-
28
-
-
79952811804
-
RIP3 mediates the embryonic lethality of caspase-8-deficient mice
-
Kaiser, W. J., Upton, J. W., Long, A. B., Livingston-Rosanoff, D., Daley-Bauer, L. P., Hakem, R., Caspary, T., and Mocarski, E. S. (2011). RIP3 mediates the embryonic lethality of caspase-8-deficient mice. Nature 471, 368-372.
-
(2011)
Nature
, vol.471
, pp. 368-372
-
-
Kaiser, W.J.1
Upton, J.W.2
Long, A.B.3
Livingston-Rosanoff, D.4
Daley-Bauer, L.P.5
Hakem, R.6
Caspary, T.7
Mocarski, E.S.8
-
29
-
-
0031918742
-
The mitochondrial death/life regulator in apoptosis and necrosis
-
Kroemer, G., Dallaporta, B., and Resche-Rigon, M. (1998). The mitochondrial death/life regulator in apoptosis and necrosis. Annu Rev Physiol 60, 619-642.
-
(1998)
Annu Rev Physiol
, vol.60
, pp. 619-642
-
-
Kroemer, G.1
Dallaporta, B.2
Resche-Rigon, M.3
-
30
-
-
0023697978
-
Tumor necrosis factor can induce both apoptic and necrotic forms of cell lysis
-
Laster, S. M., Wood, J. G., and Gooding, L. R. (1988). Tumor necrosis factor can induce both apoptic and necrotic forms of cell lysis. J Immunol 141, 2629-2634.
-
(1988)
J Immunol
, vol.141
, pp. 2629-2634
-
-
Laster, S.M.1
Wood, J.G.2
Gooding, L.R.3
-
31
-
-
6344274848
-
Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis
-
Lee, Y. J., Jeong, S. Y., Karbowski, M., Smith, C. L., and Youle, R. J. (2004). Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis. Mol Biol Cell 15, 5001-5011.
-
(2004)
Mol Biol Cell
, vol.15
, pp. 5001-5011
-
-
Lee, Y.J.1
Jeong, S.Y.2
Karbowski, M.3
Smith, C.L.4
Youle, R.J.5
-
32
-
-
84864240409
-
The RIP1/RIP3 Necrosome Forms a Functional Amyloid Signaling Complex Required for Programmed Necrosis
-
Li, J., McQuade, T., Siemer, A. B., Napetschnig, J., Moriwaki, K., Hsiao, Y. S., Damko, E., Moquin, D., Walz, T., McDermott, A., et al. (2012). The RIP1/RIP3 Necrosome Forms a Functional Amyloid Signaling Complex Required for Programmed Necrosis. Cell 150, 339-350.
-
(2012)
Cell
, vol.150
, pp. 339-350
-
-
Li, J.1
McQuade, T.2
Siemer, A.B.3
Napetschnig, J.4
Moriwaki, K.5
Hsiao, Y.S.6
Damko, E.7
Moquin, D.8
Walz, T.9
McDermott, A.10
-
33
-
-
81855183262
-
Loss of caspase-8 protects mice against inflammation-related hepatocarcinogenesis but induces non-apoptotic liver injury
-
Liedtke, C., Bangen, J. M., Freimuth, J., Beraza, N., Lambertz, D., Cubero, F. J., Hatting, M., Karlmark, K. R., Streetz, K. L., Krombach, G. A., et al. (2011). Loss of caspase-8 protects mice against inflammation-related hepatocarcinogenesis but induces non-apoptotic liver injury. Gastroenterology 141, 2176-2187.
-
(2011)
Gastroenterology
, vol.141
, pp. 2176-2187
-
-
Liedtke, C.1
Bangen, J.M.2
Freimuth, J.3
Beraza, N.4
Lambertz, D.5
Cubero, F.J.6
Hatting, M.7
Karlmark, K.R.8
Streetz, K.L.9
Krombach, G.A.10
-
34
-
-
0033043803
-
Bcl-2 alters the balance between apoptosis and necrosis, but does not prevent cell death induced by oxidized low density lipoproteins
-
Meilhac, O., Escargueil-Blanc, I., Thiers, J. C., Salvayre, R., and Negre-Salvayre, A. (1999). Bcl-2 alters the balance between apoptosis and necrosis, but does not prevent cell death induced by oxidized low density lipoproteins. FASEB J 13, 485-494.
-
(1999)
FASEB J
, vol.13
, pp. 485-494
-
-
Meilhac, O.1
Escargueil-Blanc, I.2
Thiers, J.C.3
Salvayre, R.4
Negre-Salvayre, A.5
-
35
-
-
33846429218
-
TRAIL induces receptor-interacting protein 1-dependent and caspase-dependent necrosis-like cell death under acidic extracellular conditions
-
Meurette, O., Rebillard, A., Huc, L., Le Moigne, G., Merino, D., Micheau, O., Lagadic-Gossmann, D., and Dimanche-Boitrel, M. T. (2007). TRAIL induces receptor-interacting protein 1-dependent and caspase-dependent necrosis-like cell death under acidic extracellular conditions. Cancer Res 67, 218-226.
-
(2007)
Cancer Res
, vol.67
, pp. 218-226
-
-
Meurette, O.1
Rebillard, A.2
Huc, L.3
Le Moigne, G.4
Merino, D.5
Micheau, O.6
Lagadic-Gossmann, D.7
Dimanche-Boitrel, M.T.8
-
36
-
-
0041853690
-
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
-
Micheau, O., and Tschopp, J. (2003). Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 114, 181-190.
-
(2003)
Cell
, vol.114
, pp. 181-190
-
-
Micheau, O.1
Tschopp, J.2
-
37
-
-
15844407874
-
Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death
-
Nakagawa, T., Shimizu, S., Watanabe, T., Yamaguchi, O., Otsu, K., Yamagata, H., Inohara, H., Kubo, T., and Tsujimoto, Y. (2005). Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death. Nature 434, 652-658.
-
(2005)
Nature
, vol.434
, pp. 652-658
-
-
Nakagawa, T.1
Shimizu, S.2
Watanabe, T.3
Yamaguchi, O.4
Otsu, K.5
Yamagata, H.6
Inohara, H.7
Kubo, T.8
Tsujimoto, Y.9
-
38
-
-
78650911946
-
Necrostatin decreases oxidative damage, inflammation, and injury after neonatal HI
-
Northington, F. J., Chavez-Valdez, R., Graham, E. M., Razdan, S., Gauda, E. B., and Martin, L. J. (2011). Necrostatin decreases oxidative damage, inflammation, and injury after neonatal HI. J Cereb Blood Flow Metab 31, 178-189.
-
(2011)
J Cereb Blood Flow Metab
, vol.31
, pp. 178-189
-
-
Northington, F.J.1
Chavez-Valdez, R.2
Graham, E.M.3
Razdan, S.4
Gauda, E.B.5
Martin, L.J.6
-
39
-
-
84856160569
-
Caspase 8 inhibits programmed necrosis by processing CYLD
-
O'Donnell, M. A., Perez-Jimenez, E., Oberst, A., Ng, A., Massoumi, R., Xavier, R., Green, D. R., and Ting, A. T. (2011). Caspase 8 inhibits programmed necrosis by processing CYLD. Nat Cell Biol 13, 1437-1442.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 1437-1442
-
-
O'Donnell, M.A.1
Perez-Jimenez, E.2
Oberst, A.3
Ng, A.4
Massoumi, R.5
Xavier, R.6
Green, D.R.7
Ting, A.T.8
-
40
-
-
79952810024
-
Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis
-
Oberst, A., Dillon, C. P., Weinlich, R., McCormick, L. L., Fitzgerald, P., Pop, C., Hakem, R., Salvesen, G. S., and Green, D. R. (2011). Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis. Nature 471, 363-367.
-
(2011)
Nature
, vol.471
, pp. 363-367
-
-
Oberst, A.1
Dillon, C.P.2
Weinlich, R.3
McCormick, L.L.4
Fitzgerald, P.5
Pop, C.6
Hakem, R.7
Salvesen, G.S.8
Green, D.R.9
-
41
-
-
84860584135
-
Inhibition of RIP1-dependent necrosis prevents adverse cardiac remodeling after myocardial ischemia-reperfusion in vivo
-
Oerlemans, M. I., Liu, J., Arslan, F., den Ouden, K., van Middelaar, B. J., Doevendans, P. A., and Sluijter, J. P. (2012). Inhibition of RIP1-dependent necrosis prevents adverse cardiac remodeling after myocardial ischemia-reperfusion in vivo. Basic Res Cardiol 107, 270.
-
(2012)
Basic Res Cardiol
, vol.107
, pp. 270
-
-
Oerlemans, M.I.1
Liu, J.2
Arslan, F.3
den Ouden, K.4
van Middelaar, B.J.5
Doevendans, P.A.6
Sluijter, J.P.7
-
42
-
-
33749623421
-
Inhibiting the mitochondrial fission machinery does not prevent Bax/Bak-dependent apoptosis
-
Parone, P. A., James, D. I., Da Cruz, S., Mattenberger, Y., Donze, O., Barja, F., and Martinou, J. C. (2006). Inhibiting the mitochondrial fission machinery does not prevent Bax/Bak-dependent apoptosis. Mol Cell Biol 26, 7397-7408.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 7397-7408
-
-
Parone, P.A.1
James, D.I.2
Da Cruz, S.3
Mattenberger, Y.4
Donze, O.5
Barja, F.6
Martinou, J.C.7
-
43
-
-
0037059769
-
Productive HIV-1 infection of primary CD4+ T cells induces mitochondrial membrane permeabilization leading to a caspase-independent cell death
-
Petit, F., Arnoult, D., Lelievre, J. D., Moutouh-de Parseval, L., Hance, A. J., Schneider, P., Corbeil, J., Ameisen, J. C., and Estaquier, J. (2002). Productive HIV-1 infection of primary CD4+ T cells induces mitochondrial membrane permeabilization leading to a caspase-independent cell death. J Biol Chem 277, 1477-1487.
-
(2002)
J Biol Chem
, vol.277
, pp. 1477-1487
-
-
Petit, F.1
Arnoult, D.2
Lelievre, J.D.3
Moutouh-de Parseval, L.4
Hance, A.J.5
Schneider, P.6
Corbeil, J.7
Ameisen, J.C.8
Estaquier, J.9
-
44
-
-
84866544929
-
Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium
-
(In Press)
-
Robinson, N., McComb, S., Mulligan, R., Dudani, R., Krishnan, L., and Sad, S. (2012). Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium. Nat Immunol. (In Press).
-
(2012)
Nat Immunol
-
-
Robinson, N.1
McComb, S.2
Mulligan, R.3
Dudani, R.4
Krishnan, L.5
Sad, S.6
-
45
-
-
25144480009
-
Caspase-8 deficiency in T cells leads to a lethal lymphoinfiltrative immune disorder
-
Salmena, L., and Hakem, R. (2005). Caspase-8 deficiency in T cells leads to a lethal lymphoinfiltrative immune disorder. J Exp Med 202, 727-732.
-
(2005)
J Exp Med
, vol.202
, pp. 727-732
-
-
Salmena, L.1
Hakem, R.2
-
46
-
-
49349105966
-
Bax- or Bak-induced mitochondrial fission can be uncoupled from cytochrome C release
-
Sheridan, C., Delivani, P., Cullen, S. P., and Martin, S. J. (2008). Bax- or Bak-induced mitochondrial fission can be uncoupled from cytochrome C release. Mol Cell 31, 570-585.
-
(2008)
Mol Cell
, vol.31
, pp. 570-585
-
-
Sheridan, C.1
Delivani, P.2
Cullen, S.P.3
Martin, S.J.4
-
47
-
-
84864324029
-
GRIM-19 Mediated Translocation of STAT3 to Mitochondria is Necessary for TNF Induced Necroptosis
-
(In Press)
-
Shulga, N., and Pastorino, J. G. (2012). GRIM-19 Mediated Translocation of STAT3 to Mitochondria is Necessary for TNF Induced Necroptosis. J Cell Sci. (In Press).
-
(2012)
J Cell Sci
-
-
Shulga, N.1
Pastorino, J.G.2
-
48
-
-
34548564715
-
Necrostatin: a potentially novel cardioprotective agent?
-
Smith, C. C., Davidson, S. M., Lim, S. Y., Simpkin, J. C., Hothersall, J. S., and Yellon, D. M. (2007). Necrostatin: a potentially novel cardioprotective agent? Cardiovasc Drugs Ther 21, 227-233.
-
(2007)
Cardiovasc Drugs Ther
, vol.21
, pp. 227-233
-
-
Smith, C.C.1
Davidson, S.M.2
Lim, S.Y.3
Simpkin, J.C.4
Hothersall, J.S.5
Yellon, D.M.6
-
49
-
-
84862907788
-
Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase
-
Sun, L., Wang, H., Wang, Z., He, S., Chen, S., Liao, D., Wang, L., Yan, J., Liu, W., Lei, X., et al. (2012). Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase. Cell 148, 213-227.
-
(2012)
Cell
, vol.148
, pp. 213-227
-
-
Sun, L.1
Wang, H.2
Wang, Z.3
He, S.4
Chen, S.5
Liao, D.6
Wang, L.7
Yan, J.8
Liu, W.9
Lei, X.10
-
50
-
-
34547143110
-
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
-
Takaoka, A., Wang, Z., Choi, M. K., Yanai, H., Negishi, H., Ban, T., Lu, Y., Miyagishi, M., Kodama, T., Honda, K., et al. (2007). DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response. Nature 448, 501-505.
-
(2007)
Nature
, vol.448
, pp. 501-505
-
-
Takaoka, A.1
Wang, Z.2
Choi, M.K.3
Yanai, H.4
Negishi, H.5
Ban, T.6
Lu, Y.7
Miyagishi, M.8
Kodama, T.9
Honda, K.10
-
51
-
-
68149128514
-
Mitochondrial phosphoglycerate mutase 5 uses alternate catalytic activity as a protein serine/threonine phosphatase to activate ASK1
-
Takeda, K., Komuro, Y., Hayakawa, T., Oguchi, H., Ishida, Y., Murakami, S., Noguchi, T., Kinoshita, H., Sekine, Y., Iemura, S., et al. (2009). Mitochondrial phosphoglycerate mutase 5 uses alternate catalytic activity as a protein serine/threonine phosphatase to activate ASK1. Proc Natl Acad Sci U S A 106, 12301-12305.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 12301-12305
-
-
Takeda, K.1
Komuro, Y.2
Hayakawa, T.3
Oguchi, H.4
Ishida, Y.5
Murakami, S.6
Noguchi, T.7
Kinoshita, H.8
Sekine, Y.9
Iemura, S.10
-
52
-
-
79960921946
-
The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs
-
Tenev, T., Bianchi, K., Darding, M., Broemer, M., Langlais, C., Wallberg, F., Zachariou, A., Lopez, J., MacFarlane, M., Cain, K., et al. (2011). The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs. Mol Cell 43, 432-448.
-
(2011)
Mol Cell
, vol.43
, pp. 432-448
-
-
Tenev, T.1
Bianchi, K.2
Darding, M.3
Broemer, M.4
Langlais, C.5
Wallberg, F.6
Zachariou, A.7
Lopez, J.8
MacFarlane, M.9
Cain, K.10
-
53
-
-
78650718758
-
Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis
-
Trichonas, G., Murakami, Y., Thanos, A., Morizane, Y., Kayama, M., Debouck, C. M., Hisatomi, T., Miller, J. W., and Vavvas, D. G. (2010). Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis. Proc Natl Acad Sci U S A 107, 21695-21700.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 21695-21700
-
-
Trichonas, G.1
Murakami, Y.2
Thanos, A.3
Morizane, Y.4
Kayama, M.5
Debouck, C.M.6
Hisatomi, T.7
Miller, J.W.8
Vavvas, D.G.9
-
54
-
-
34247485841
-
Role of the mitochondrial membrane permeability transition in cell death
-
Tsujimoto, Y., and Shimizu, S. (2007). Role of the mitochondrial membrane permeability transition in cell death. Apoptosis 12, 835-840.
-
(2007)
Apoptosis
, vol.12
, pp. 835-840
-
-
Tsujimoto, Y.1
Shimizu, S.2
-
55
-
-
0030796183
-
Bcl-2 and Bcl-xL block apoptosis as well as necrosis: possible involvement of common mediators in apoptotic and necrotic signal transduction pathways
-
Tsujimoto, Y., Shimizu, S., Eguchi, Y., Kamiike, W., and Matsuda, H. (1997). Bcl-2 and Bcl-xL block apoptosis as well as necrosis: possible involvement of common mediators in apoptotic and necrotic signal transduction pathways. Leukemia 11Suppl 3, 380-382.
-
(1997)
Leukemia
, vol.11
, Issue.SUPPL. 3
, pp. 380-382
-
-
Tsujimoto, Y.1
Shimizu, S.2
Eguchi, Y.3
Kamiike, W.4
Matsuda, H.5
-
56
-
-
77954593965
-
Virus inhibition of RIP3-dependent necrosis
-
Upton, J. W., Kaiser, W. J., and Mocarski, E. S. (2010). Virus inhibition of RIP3-dependent necrosis. Cell Host Microbe 7, 302-313.
-
(2010)
Cell Host Microbe
, vol.7
, pp. 302-313
-
-
Upton, J.W.1
Kaiser, W.J.2
Mocarski, E.S.3
-
57
-
-
84858420051
-
DAI/ZBP1/DLM-1 complexes with RIP3 to mediate virus-induced programmed necrosis that is targeted by murine cytomegalovirus vIRA
-
Upton, J. W., Kaiser, W. J., and Mocarski, E. S. (2012). DAI/ZBP1/DLM-1 complexes with RIP3 to mediate virus-induced programmed necrosis that is targeted by murine cytomegalovirus vIRA. Cell Host Microbe 11, 290-297.
-
(2012)
Cell Host Microbe
, vol.11
, pp. 290-297
-
-
Upton, J.W.1
Kaiser, W.J.2
Mocarski, E.S.3
-
58
-
-
77957105977
-
Molecular mechanisms of necroptosis: an ordered cellular explosion
-
Vandenabeele, P., Galluzzi, L., Vanden Berghe, T., and Kroemer, G. (2010). Molecular mechanisms of necroptosis: an ordered cellular explosion. Nat Rev Mol Cell Biol 11, 700-714.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 700-714
-
-
Vandenabeele, P.1
Galluzzi, L.2
Vanden Berghe, T.3
Kroemer, G.4
-
59
-
-
83155192804
-
TNF-induced necroptosis in L929 cells is tightly regulated by multiple TNFR1 complex I and II members
-
Vanlangenakker, N., Bertrand, M. J., Bogaert, P., Vandenabeele, P., and Vanden Berghe, T. (2011a). TNF-induced necroptosis in L929 cells is tightly regulated by multiple TNFR1 complex I and II members. Cell Death Dis 2, e230.
-
(2011)
Cell Death Dis
, vol.2
-
-
Vanlangenakker, N.1
Bertrand, M.J.2
Bogaert, P.3
Vandenabeele, P.4
Vanden Berghe, T.5
-
60
-
-
79952623655
-
cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production
-
Vanlangenakker, N., Vanden Berghe, T., Bogaert, P., Laukens, B., Zobel, K., Deshayes, K., Vucic, D., Fulda, S., Vandenabeele, P., and Bertrand, M. J. (2011b). cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production. Cell Death Differ 18, 656-665.
-
(2011)
Cell Death Differ
, vol.18
, pp. 656-665
-
-
Vanlangenakker, N.1
Vanden Berghe, T.2
Bogaert, P.3
Laukens, B.4
Zobel, K.5
Deshayes, K.6
Vucic, D.7
Fulda, S.8
Vandenabeele, P.9
Bertrand, M.J.10
-
61
-
-
84856759660
-
Many stimuli pull the necrotic trigger, an overview
-
Vanlangenakker, N., Vanden Berghe, T., and Vandenabeele, P. (2012). Many stimuli pull the necrotic trigger, an overview. Cell Death Differ 19, 75-86.
-
(2012)
Cell Death Differ
, vol.19
, pp. 75-86
-
-
Vanlangenakker, N.1
Vanden Berghe, T.2
Vandenabeele, P.3
-
62
-
-
0032482169
-
Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor
-
Vercammen, D., Beyaert, R., Denecker, G., Goossens, V., van Loo, G., Declercq, W., Grooten, J., Fiers, W., and Vandenabeele, P. (1998a). Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor. J Exp Med 187, 1477-1485.
-
(1998)
J Exp Med
, vol.187
, pp. 1477-1485
-
-
Vercammen, D.1
Beyaert, R.2
Denecker, G.3
Goossens, V.4
van Loo, G.5
Declercq, W.6
Grooten, J.7
Fiers, W.8
Vandenabeele, P.9
-
63
-
-
0032494143
-
Dual signaling of the Fas receptor: initiation of both apoptotic and necrotic cell death pathways
-
Vercammen, D., Brouckaert, G., Denecker, G., van de Craen, M., Declercq, W., Fiers, W., and Vandenabeele, P. (1998b). Dual signaling of the Fas receptor: initiation of both apoptotic and necrotic cell death pathways. J Exp Med 188, 919-930.
-
(1998)
J Exp Med
, vol.188
, pp. 919-930
-
-
Vercammen, D.1
Brouckaert, G.2
Denecker, G.3
van de Craen, M.4
Declercq, W.5
Fiers, W.6
Vandenabeele, P.7
-
64
-
-
43049152912
-
TNF-alpha induces two distinct caspase-8 activation pathways
-
Wang, L., Du, F., and Wang, X. (2008). TNF-alpha induces two distinct caspase-8 activation pathways. Cell 133, 693-703.
-
(2008)
Cell
, vol.133
, pp. 693-703
-
-
Wang, L.1
Du, F.2
Wang, X.3
-
65
-
-
84862909353
-
The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways
-
Wang, Z., Jiang, H., Chen, S., Du, F., and Wang, X. (2012). The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways. Cell 148, 228-243.
-
(2012)
Cell
, vol.148
, pp. 228-243
-
-
Wang, Z.1
Jiang, H.2
Chen, S.3
Du, F.4
Wang, X.5
-
66
-
-
80052850704
-
FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation
-
Welz, P. S., Wullaert, A., Vlantis, K., Kondylis, V., Fernandez-Majada, V., Ermolaeva, M., Kirsch, P., Sterner-Kock, A., van Loo, G., and Pasparakis, M. (2011). FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation. Nature 477, 330-334.
-
(2011)
Nature
, vol.477
, pp. 330-334
-
-
Welz, P.S.1
Wullaert, A.2
Vlantis, K.3
Kondylis, V.4
Fernandez-Majada, V.5
Ermolaeva, M.6
Kirsch, P.7
Sterner-Kock, A.8
van Loo, G.9
Pasparakis, M.10
-
67
-
-
35548974703
-
Regulation of early wave of germ cell apoptosis and spermatogenesis by deubiquitinating enzyme CYLD
-
Wright, A., Reiley, W. W., Chang, M., Jin, W., Lee, A. J., Zhang, M., and Sun, S. C. (2007). Regulation of early wave of germ cell apoptosis and spermatogenesis by deubiquitinating enzyme CYLD. Dev Cell 13, 705-716.
-
(2007)
Dev Cell
, vol.13
, pp. 705-716
-
-
Wright, A.1
Reiley, W.W.2
Chang, M.3
Jin, W.4
Lee, A.J.5
Zhang, M.6
Sun, S.C.7
-
68
-
-
33645703930
-
Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]
-
Wu, C. J., Conze, D. B., Li, T., Srinivasula, S. M., and Ashwell, J. D. (2006). Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]. Nat Cell Biol 8, 398-406.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 398-406
-
-
Wu, C.J.1
Conze, D.B.2
Li, T.3
Srinivasula, S.M.4
Ashwell, J.D.5
-
69
-
-
67650812332
-
RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis
-
Zhang, D. W., Shao, J., Lin, J., Zhang, N., Lu, B. J., Lin, S. C., Dong, M. Q., and Han, J. (2009). RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. Science 325, 332-336.
-
(2009)
Science
, vol.325
, pp. 332-336
-
-
Zhang, D.W.1
Shao, J.2
Lin, J.3
Zhang, N.4
Lu, B.J.5
Lin, S.C.6
Dong, M.Q.7
Han, J.8
-
70
-
-
79952780505
-
Functional complementation between FADD and RIP1 in embryos and lymphocytes
-
Zhang, H., Zhou, X., McQuade, T., Li, J., Chan, F. K., and Zhang, J. (2011). Functional complementation between FADD and RIP1 in embryos and lymphocytes. Nature 471, 373-376.
-
(2011)
Nature
, vol.471
, pp. 373-376
-
-
Zhang, H.1
Zhou, X.2
McQuade, T.3
Li, J.4
Chan, F.K.5
Zhang, J.6
-
71
-
-
84859467770
-
Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis
-
Zhao, J., Jitkaew, S., Cai, Z., Choksi, S., Li, Q., Luo, J., and Liu, Z. G. (2012). Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis. Proc Natl Acad Sci U S A 109, 5322-5327.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 5322-5327
-
-
Zhao, J.1
Jitkaew, S.2
Cai, Z.3
Choksi, S.4
Li, Q.5
Luo, J.6
Liu, Z.G.7
|