Inhibition of Apoptosis Protects Mice from Ethanol-Mediated Acceleration of Early Markers of CCl4-Induced Fibrosis but not Steatosis or Inflammation

Alcoholism: Clinical and Experimental Research

Volumn 36, Issue 7, 2012, Pages 1139-1147

  Roychowdhury, Sanjoy ^a   Chiang, Dian J ^a   Mandal, Palash ^a,c   McMullen, Megan R ^a   Liu, Xiuli ^a   Cohen, Jessica I ^a   Pollard, John ^b   Feldstein, Ariel E ^a   Nagy, Laura E ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b VERTEX PHARMACEUTICALS   (United States)

^c BIRLA INSTITUTE OF TECHNOLOGY AND SCIENCE   (India)

Author keywords

Alcoholic liver disease; Bid; Caspase; Cell death; Necroptosis

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL; ALPHA SMOOTH MUSCLE ACTIN; APOPTOSIS INHIBITOR; ASPARTATE AMINOTRANSFERASE; CARBON TETRACHLORIDE; CASPASE INHIBITOR; CYTOKERATIN 18; PROTEIN BID; PROTEIN KINASE; RECEPTOR INTERACTING PROTEIN KINASE 3; SCLEROPROTEIN; UNCLASSIFIED DRUG; VX 166;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; HEPATITIS; LIVER FIBROSIS; LIVER PROTECTION; MOUSE; NECROPTOSIS; NONALCOHOLIC FATTY LIVER; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STELLATE CELL;

ANIMALS; APOPTOSIS; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; BIOLOGICAL MARKERS; CARBON TETRACHLORIDE; ETHANOL; FATTY LIVER, ALCOHOLIC; FEMALE; HEPATITIS, ALCOHOLIC; HEPATOCYTES; INFLAMMATION MEDIATORS; LIVER CIRRHOSIS, ALCOHOLIC; LIVER DISEASES, ALCOHOLIC; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT;

MUS;

EID: 84863784919     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/j.1530-0277.2011.01720.x     Document Type: Article

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