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Volumn 11, Issue 1, 2014, Pages

Amino acid supplementation and impact on immune function in the context of exercise

Author keywords

Immunonutrition; L arginine; L glutamine; L leucine; Oxidative stress

Indexed keywords


EID: 84989325588     PISSN: None     EISSN: 15502783     Source Type: Journal    
DOI: 10.1186/s12970-014-0061-8     Document Type: Review
Times cited : (112)

References (131)
  • 1
    • 33645522610 scopus 로고    scopus 로고
    • Oxidative stress: relationship with exercise and training
    • Finaud J, Lac G, Filaire E: Oxidative stress: relationship with exercise and training. Sports Med 2006, 36:327-358.
    • (2006) Sports Med , vol.36 , pp. 327-358
    • Finaud, J.1    Lac, G.2    Filaire, E.3
  • 2
    • 34547626210 scopus 로고    scopus 로고
    • Immune function in sport and exercise
    • Gleeson M: Immune function in sport and exercise. J Appl Physiol 2007, 103:693-699.
    • (2007) J Appl Physiol , vol.103 , pp. 693-699
    • Gleeson, M.1
  • 3
    • 77949391048 scopus 로고    scopus 로고
    • Altered oxidative stress in overtrained athletes
    • Tanskanen M, Atalay M, Uusitalo A: Altered oxidative stress in overtrained athletes. J Sports Sci 2010, 28:309-317.
    • (2010) J Sports Sci , vol.28 , pp. 309-317
    • Tanskanen, M.1    Atalay, M.2    Uusitalo, A.3
  • 5
    • 84857673412 scopus 로고    scopus 로고
    • Overtraining syndrome: a practical guide
    • Kreher JB, Schwartz JB: Overtraining syndrome: a practical guide. Sports Health 2012, 4:128-138.
    • (2012) Sports Health , vol.4 , pp. 128-138
    • Kreher, J.B.1    Schwartz, J.B.2
  • 6
    • 84868681268 scopus 로고    scopus 로고
    • Understanding the properties of common dietary supplements: clinical implications for healthcare practitioners
    • Zelig R, Rigassio Radler D: Understanding the properties of common dietary supplements: clinical implications for healthcare practitioners. Nutr Clin Pract 2012, 27:767-776.
    • (2012) Nutr Clin Pract , vol.27 , pp. 767-776
    • Zelig, R.1    Rigassio Radler, D.2
  • 7
    • 24644517189 scopus 로고    scopus 로고
    • Nutritional supplement practices in UK junior National track and field athletes
    • Nieper A: Nutritional supplement practices in UK junior National track and field athletes. Br J Sports Med 2005, 39:645-649.
    • (2005) Br J Sports Med , vol.39 , pp. 645-649
    • Nieper, A.1
  • 9
    • 84881086390 scopus 로고    scopus 로고
    • To supplement or not to supplement: a metabolic network framework for human nutritional supplements
    • Nogiec CD, Kasif S: To supplement or not to supplement: a metabolic network framework for human nutritional supplements. PLoS One 2013, 8:e68751.
    • (2013) PLoS One , vol.8
    • Nogiec, C.D.1    Kasif, S.2
  • 10
    • 27044440604 scopus 로고
    • Further observations on the system ascorbic acid-glutathione-ascorbic acid-oxidase
    • Crook EM, Hopkins FG: Further observations on the system ascorbic acid-glutathione-ascorbic acid-oxidase. Biochem J 1938, 32:1356-1363.
    • (1938) Biochem J , vol.32 , pp. 1356-1363
    • Crook, E.M.1    Hopkins, F.G.2
  • 11
    • 79952784010 scopus 로고    scopus 로고
    • Emerging paradigms in immunonutrition
    • Satyaraj E: Emerging paradigms in immunonutrition. Top Companion Anim Med 2011, 26:25-32.
    • (2011) Top Companion Anim Med , vol.26 , pp. 25-32
    • Satyaraj, E.1
  • 12
    • 0036708011 scopus 로고    scopus 로고
    • Exercise-induced immunodepression- plasma glutamine is not the link
    • Hiscock N, Pedersen BK: Exercise-induced immunodepression- plasma glutamine is not the link. J Appl Physiol 2002, 93:813-822.
    • (2002) J Appl Physiol , vol.93 , pp. 813-822
    • Hiscock, N.1    Pedersen, B.K.2
  • 13
    • 27144483006 scopus 로고    scopus 로고
    • Exercise as a time-conditioning effector in chronic disease: a complementary treatment strategy
    • Costa Rosa LF: Exercise as a time-conditioning effector in chronic disease: a complementary treatment strategy. Evid Based Complement Alternat Med 2004, 1:63-70.
    • (2004) Evid Based Complement Alternat Med , vol.1 , pp. 63-70
    • Costa Rosa, L.F.1
  • 14
    • 0034556980 scopus 로고    scopus 로고
    • Inflammatory cytokines in nonpathological States
    • Cannon JG: Inflammatory cytokines in nonpathological States. News Physiol Sci 2000, 15:298-303.
    • (2000) News Physiol Sci , vol.15 , pp. 298-303
    • Cannon, J.G.1
  • 17
    • 0030815974 scopus 로고    scopus 로고
    • Prolonged submaximal eccentric exercise is associated with increased levels of plasma IL-6
    • Rohde TMD, Richter EA, Kiens B, Pedersen BK: Prolonged submaximal eccentric exercise is associated with increased levels of plasma IL-6. Am J Physiol 1997, 273:E85-E91.
    • (1997) Am J Physiol , vol.273 , pp. E85-E91
    • Rohde, T.M.D.1    Richter, E.A.2    Kiens, B.3    Pedersen, B.K.4
  • 18
    • 0033557703 scopus 로고    scopus 로고
    • Pro- and anti-inflammatory cytokine balance in strenuous exercise in humans
    • Ostrowski K, Rohde T, Asp S, Schjerling P, Pedersen BK: Pro- and anti-inflammatory cytokine balance in strenuous exercise in humans. J Physiol 1999, 515(Pt 1):287-291.
    • (1999) J Physiol , vol.515 , pp. 287-291
    • Ostrowski, K.1    Rohde, T.2    Asp, S.3    Schjerling, P.4    Pedersen, B.K.5
  • 21
    • 4344594047 scopus 로고    scopus 로고
    • Exercise immunology: the current state of man and mouse
    • Malm C: Exercise immunology: the current state of man and mouse. Sports Med 2004, 34:555-566.
    • (2004) Sports Med , vol.34 , pp. 555-566
    • Malm, C.1
  • 26
    • 15444374348 scopus 로고    scopus 로고
    • The anti-inflammatory effect of exercise
    • Petersen AM, Pedersen BK: The anti-inflammatory effect of exercise. J Appl Physiol 2005, 98:1154-1162.
    • (2005) J Appl Physiol , vol.98 , pp. 1154-1162
    • Petersen, A.M.1    Pedersen, B.K.2
  • 27
  • 28
    • 0035886973 scopus 로고    scopus 로고
    • Muscle-derived interleukin-6: possible biological effects
    • Pedersen BK, Steensberg A, Schjerling P: Muscle-derived interleukin-6: possible biological effects. J Physiol 2001, 536:329-337.
    • (2001) J Physiol , vol.536 , pp. 329-337
    • Pedersen, B.K.1    Steensberg, A.2    Schjerling, P.3
  • 29
    • 84893957626 scopus 로고    scopus 로고
    • Elevated levels of extracellular heat-shock protein 72 (eHSP72) are positively correlated with insulin resistance in vivo and cause pancreatic beta-cell dysfunction and death in vitro
    • Krause M, Keane K, Rodrigues-Krause J, Crognale D, Egan B, De Vito G, Murphy C, Newsholme P: Elevated levels of extracellular heat-shock protein 72 (eHSP72) are positively correlated with insulin resistance in vivo and cause pancreatic beta-cell dysfunction and death in vitro. Clin Sci 2014, 126:739-752.
    • (2014) Clin Sci , vol.126 , pp. 739-752
    • Krause, M.1    Keane, K.2    Rodrigues-Krause, J.3    Crognale, D.4    Egan, B.5    De Vito, G.6    Murphy, C.7    Newsholme, P.8
  • 30
    • 78651072127 scopus 로고    scopus 로고
    • Extracellular heat shock proteins (eHSP70) in exercise: possible targets outside the immune system and their role for neurodegenerative disorders treatment
    • Krause M, Rodrigues-Krause Jda C: Extracellular heat shock proteins (eHSP70) in exercise: possible targets outside the immune system and their role for neurodegenerative disorders treatment. Med Hypotheses 2011, 76:286-290.
    • (2011) Med Hypotheses , vol.76 , pp. 286-290
    • Krause, M.1    Rodrigues-Krause Jda, C.2
  • 31
    • 84904107498 scopus 로고    scopus 로고
    • The importance of the cellular stress response in the pathogenesis and treatment of type 2 diabetes
    • Hooper PL, Balogh G, Rivas E, Kavanagh K, Vigh L: The importance of the cellular stress response in the pathogenesis and treatment of type 2 diabetes. Cell Stress Chaperones 2014, 19(4):447-464.
    • (2014) Cell Stress Chaperones , vol.19 , Issue.4 , pp. 447-464
    • Hooper, P.L.1    Balogh, G.2    Rivas, E.3    Kavanagh, K.4    Vigh, L.5
  • 32
    • 46749108066 scopus 로고    scopus 로고
    • Type 1 diabetes: can exercise impair the autoimmune event? The L-arginine/glutamine coupling hypothesis
    • Krause Mda S, de Bittencourt PI Jr: Type 1 diabetes: can exercise impair the autoimmune event? The L-arginine/glutamine coupling hypothesis. Cell Biochem Funct 2008, 26:406-433.
    • (2008) Cell Biochem Funct , vol.26 , pp. 406-433
    • Krause Mda, S.1    Bittencourt, P.I.2
  • 33
    • 79953708224 scopus 로고    scopus 로고
    • HSP70 expression: does it a novel fatigue signalling factor from immune system to the brain?
    • Heck TG, Scholer CM, de Bittencourt PI: HSP70 expression: does it a novel fatigue signalling factor from immune system to the brain? Cell Biochem Funct 2011, 29:215-226.
    • (2011) Cell Biochem Funct , vol.29 , pp. 215-226
    • Heck, T.G.1    Scholer, C.M.2    de Bittencourt, P.I.3
  • 34
    • 84891828707 scopus 로고    scopus 로고
    • Alanyl-glutamine and glutamine plus alanine supplements improve skeletal redox status in trained rats: involvement of heat shock protein pathways
    • Petry ER, Cruzat VF, Heck TG, Leite JS, Homem de Bittencourt PI Jr, Tirapegui J: Alanyl-glutamine and glutamine plus alanine supplements improve skeletal redox status in trained rats: involvement of heat shock protein pathways. Life Sci 2014, 94:130-136.
    • (2014) Life Sci , vol.94 , pp. 130-136
    • Petry, E.R.1    Cruzat, V.F.2    Heck, T.G.3    Leite, J.S.4    Bittencourt, H.P.I.5    Tirapegui, J.6
  • 36
    • 84898901821 scopus 로고    scopus 로고
    • Extracellular Hsp72 concentration relates to a minimum endogenous criteria during acute exercise-heat exposure
    • Gibson OR, Dennis A, Parfitt T, Taylor L, Watt PW, Maxwell NS: Extracellular Hsp72 concentration relates to a minimum endogenous criteria during acute exercise-heat exposure. Cell Stress Chaperones 2014, 19:389-400.
    • (2014) Cell Stress Chaperones , vol.19 , pp. 389-400
    • Gibson, O.R.1    Dennis, A.2    Parfitt, T.3    Taylor, L.4    Watt, P.W.5    Maxwell, N.S.6
  • 40
    • 0029015250 scopus 로고
    • Light concentric exercise and heavy eccentric muscle loading: effects on CK, MRI and markers of inflammation
    • Sorichter S, Koller A, Haid C, Wicke K, Judmaier W, Werner P, Raas E: Light concentric exercise and heavy eccentric muscle loading: effects on CK, MRI and markers of inflammation. Int J Sports Med 1995, 16:288-295.
    • (1995) Int J Sports Med , vol.16 , pp. 288-295
    • Sorichter, S.1    Koller, A.2    Haid, C.3    Wicke, K.4    Judmaier, W.5    Werner, P.6    Raas, E.7
  • 41
    • 33745447391 scopus 로고    scopus 로고
    • Effect of high dose vitamin C supplementation on muscle soreness, damage, function, and oxidative stress to eccentric exercise
    • Bryer SC, Goldfarb AH: Effect of high dose vitamin C supplementation on muscle soreness, damage, function, and oxidative stress to eccentric exercise. Int J Sport Nutr Exerc Metab 2006, 16:270-280.
    • (2006) Int J Sport Nutr Exerc Metab , vol.16 , pp. 270-280
    • Bryer, S.C.1    Goldfarb, A.H.2
  • 42
    • 33947514541 scopus 로고    scopus 로고
    • Systemic inflammatory responses to maximal versus submaximal lengthening contractions of the elbow flexors
    • Peake JM, Nosaka K, Muthalib M, Suzuki K: Systemic inflammatory responses to maximal versus submaximal lengthening contractions of the elbow flexors. Exerc Immunol Rev 2006, 12:72-85.
    • (2006) Exerc Immunol Rev , vol.12 , pp. 72-85
    • Peake, J.M.1    Nosaka, K.2    Muthalib, M.3    Suzuki, K.4
  • 43
    • 34547691220 scopus 로고    scopus 로고
    • Response and adaptation of skeletal muscle to exercise-the role of reactive oxygen species
    • Niess AM, Simon P: Response and adaptation of skeletal muscle to exercise-the role of reactive oxygen species. Front Biosci 2007, 12:4826-4838.
    • (2007) Front Biosci , vol.12 , pp. 4826-4838
    • Niess, A.M.1    Simon, P.2
  • 44
    • 60749121729 scopus 로고    scopus 로고
    • Effects of oral supplementation with glutamine and alanyl-glutamine on glutamine, glutamate, and glutathione status in trained rats and subjected to long-duration exercise
    • Cruzat VF, Tirapegui J: Effects of oral supplementation with glutamine and alanyl-glutamine on glutamine, glutamate, and glutathione status in trained rats and subjected to long-duration exercise. Nutrition 2009, 25:428-435.
    • (2009) Nutrition , vol.25 , pp. 428-435
    • Cruzat, V.F.1    Tirapegui, J.2
  • 47
    • 74049133997 scopus 로고    scopus 로고
    • Effects of supplementation with free glutamine and the dipeptide alanyl-glutamine on parameters of muscle damage and inflammation in rats submitted to prolonged exercise
    • Cruzat VF, Rogero MM, Tirapegui J: Effects of supplementation with free glutamine and the dipeptide alanyl-glutamine on parameters of muscle damage and inflammation in rats submitted to prolonged exercise. Cell Biochem Funct 2010, 28:24-30.
    • (2010) Cell Biochem Funct , vol.28 , pp. 24-30
    • Cruzat, V.F.1    Rogero, M.M.2    Tirapegui, J.3
  • 48
    • 0012971383 scopus 로고    scopus 로고
    • Overloaded training increases exercise-induced oxidative stress and damage
    • Palazzetti S, Richard MJ, Favier A, Margaritis I: Overloaded training increases exercise-induced oxidative stress and damage. Can J Appl Physiol 2003, 28:588-604.
    • (2003) Can J Appl Physiol , vol.28 , pp. 588-604
    • Palazzetti, S.1    Richard, M.J.2    Favier, A.3    Margaritis, I.4
  • 49
    • 37849040918 scopus 로고    scopus 로고
    • Free radicals and muscle fatigue: of ROS, canaries, and the IOC
    • Reid MB: Free radicals and muscle fatigue: of ROS, canaries, and the IOC. Free Radic Biol Med 2008, 44:169-179.
    • (2008) Free Radic Biol Med , vol.44 , pp. 169-179
    • Reid, M.B.1
  • 50
    • 27744501835 scopus 로고    scopus 로고
    • Metabolic and sarcoplasmic reticulum Ca2+ cycling responses in human muscle 4 days following prolonged exercise
    • Duhamel TA, Green HJ, Perco JG, Ouyang J: Metabolic and sarcoplasmic reticulum Ca2+ cycling responses in human muscle 4 days following prolonged exercise. Can J Physiol Pharmacol 2005, 83:643-655.
    • (2005) Can J Physiol Pharmacol , vol.83 , pp. 643-655
    • Duhamel, T.A.1    Green, H.J.2    Perco, J.G.3    Ouyang, J.4
  • 52
    • 84874543773 scopus 로고    scopus 로고
    • Cross-talk between skeletal muscle and immune cells: muscle-derived mediators and metabolic implications
    • Pillon NJ, Bilan PJ, Fink LN, Klip A: Cross-talk between skeletal muscle and immune cells: muscle-derived mediators and metabolic implications. Am J Physiol Endocrinol Metab 2013, 304:E453-E465.
    • (2013) Am J Physiol Endocrinol Metab , vol.304 , pp. E453-E465
    • Pillon, N.J.1    Bilan, P.J.2    Fink, L.N.3    Klip, A.4
  • 54
    • 37849002320 scopus 로고    scopus 로고
    • Modulation of skeletal muscle antioxidant defense by exercise: Role of redox signaling
    • Ji LL: Modulation of skeletal muscle antioxidant defense by exercise: Role of redox signaling. Free Radic Biol Med 2008, 44:142-152.
    • (2008) Free Radic Biol Med , vol.44 , pp. 142-152
    • Ji, L.L.1
  • 55
    • 1542376929 scopus 로고    scopus 로고
    • Glutathione metabolism and its implications for health
    • Wu G, Fang YZ, Yang S, Lupton JR, Turner ND: Glutathione metabolism and its implications for health. J Nutr 2004, 134:489-492.
    • (2004) J Nutr , vol.134 , pp. 489-492
    • Wu, G.1    Fang, Y.Z.2    Yang, S.3    Lupton, J.R.4    Turner, N.D.5
  • 56
    • 79951925670 scopus 로고    scopus 로고
    • BJSM reviews: A to Z of nutritional supplements: dietary supplements, sports nutrition foods and ergogenic aids for health and performance-part 18
    • Newsholme P, Krause M, Newsholme EA, Stear SJ, Burke LM, Castell LM: BJSM reviews: A to Z of nutritional supplements: dietary supplements, sports nutrition foods and ergogenic aids for health and performance-part 18. Br J Sports Med 2011, 45:230-232.
    • (2011) Br J Sports Med , vol.45 , pp. 230-232
    • Newsholme, P.1    Krause, M.2    Newsholme, E.A.3    Stear, S.J.4    Burke, L.M.5    Castell, L.M.6
  • 59
    • 0034843181 scopus 로고    scopus 로고
    • Why is L-glutamine metabolism important to cells of the immune system in health, postinjury, surgery or infection?
    • discussion 2523S-2514S
    • Newsholme P: Why is L-glutamine metabolism important to cells of the immune system in health, postinjury, surgery or infection? J Nutr 2001, 131:2515S-2522S. discussion 2523S-2514S.
    • (2001) J Nutr , vol.131 , pp. 2515S-2522S
    • Newsholme, P.1
  • 61
    • 84893635232 scopus 로고    scopus 로고
    • Oral supplementations with free and dipeptide forms of L-glutamine in endotoxemic mice: effects on muscle glutamine-glutathione axis and heat shock proteins
    • Cruzat VF, Pantaleao LC, Donato J Jr, de Bittencourt PI Jr, Tirapegui J: Oral supplementations with free and dipeptide forms of L-glutamine in endotoxemic mice: effects on muscle glutamine-glutathione axis and heat shock proteins. J Nutr Biochem 2014, 25:345-352.
    • (2014) J Nutr Biochem , vol.25 , pp. 345-352
    • Cruzat, V.F.1    Pantaleao, L.C.2    Donato, J.3    Bittencourt, P.I.4    Tirapegui, J.5
  • 62
    • 54749127018 scopus 로고    scopus 로고
    • Clinical use of glutamine supplementation
    • Wernerman J: Clinical use of glutamine supplementation. J Nutr 2008, 138:2040S-2044S.
    • (2008) J Nutr , vol.138 , pp. 2040S-2044S
    • Wernerman, J.1
  • 64
    • 54749108002 scopus 로고    scopus 로고
    • Nonnutritive effects of glutamine
    • Roth E: Nonnutritive effects of glutamine. J Nutr 2008, 138:2025S-2031S.
    • (2008) J Nutr , vol.138 , pp. 2025S-2031S
    • Roth, E.1
  • 66
    • 0030874363 scopus 로고    scopus 로고
    • The effects of oral glutamine supplementation on athletes after prolonged, exhaustive exercise
    • Castell LM, Newsholme EA: The effects of oral glutamine supplementation on athletes after prolonged, exhaustive exercise. Nutrition 1997, 13:738-742.
    • (1997) Nutrition , vol.13 , pp. 738-742
    • Castell, L.M.1    Newsholme, E.A.2
  • 70
    • 1642307100 scopus 로고    scopus 로고
    • Plasma and tissue glutamine response to acute and chronic supplementation with L-glutamine and L-alanyl-L-glutamine in rats
    • Rogero MM, Tirapegui J, Pedrosa RG, Pires ISD, de Castro IA: Plasma and tissue glutamine response to acute and chronic supplementation with L-glutamine and L-alanyl-L-glutamine in rats. Nutr Res 2004, 24:261-270.
    • (2004) Nutr Res , vol.24 , pp. 261-270
    • Rogero, M.M.1    Tirapegui, J.2    Pedrosa, R.G.3    Pires, I.S.D.4    de Castro, I.A.5
  • 72
    • 33645976842 scopus 로고    scopus 로고
    • Effect of alanyl-glutamine supplementation on plasma and tissue glutamine concentrations in rats submitted to exhaustive exercise
    • Rogero MM, Tirapegui J, Pedrosa RG, de Castro IA, Pires ISD: Effect of alanyl-glutamine supplementation on plasma and tissue glutamine concentrations in rats submitted to exhaustive exercise. Nutrition 2006, 22:564-571.
    • (2006) Nutrition , vol.22 , pp. 564-571
    • Rogero, M.M.1    Tirapegui, J.2    Pedrosa, R.G.3    de Castro, I.A.4    Pires, I.S.D.5
  • 76
    • 84901627098 scopus 로고    scopus 로고
    • Nutrient regulation of insulin secretion and action
    • Newsholme P, Cruzat V, Arfuso F, Keane K: Nutrient regulation of insulin secretion and action. J Endocrinol 2014, 221:R105-R120.
    • (2014) J Endocrinol , vol.221 , pp. R105-R120
    • Newsholme, P.1    Cruzat, V.2    Arfuso, F.3    Keane, K.4
  • 77
    • 84894703144 scopus 로고    scopus 로고
    • Sirtuin-1 is a nutrient-dependent modulator of inflammation
    • Kotas ME, Gorecki MC, Gillum MP: Sirtuin-1 is a nutrient-dependent modulator of inflammation. Adipocyte 2013, 2:113-118.
    • (2013) Adipocyte , vol.2 , pp. 113-118
    • Kotas, M.E.1    Gorecki, M.C.2    Gillum, M.P.3
  • 79
    • 84867871977 scopus 로고    scopus 로고
    • Differential nitric oxide levels in the blood and skeletal muscle of type 2 diabetic subjects may be consequence of adiposity: a preliminary study
    • Krause M, Rodrigues-Krause J, O'Hagan C, De Vito G, Boreham C, Susta D, Newsholme P, Murphy C: Differential nitric oxide levels in the blood and skeletal muscle of type 2 diabetic subjects may be consequence of adiposity: a preliminary study. Metabolism 2012, 61:1528-1537.
    • (2012) Metabolism , vol.61 , pp. 1528-1537
    • Krause, M.1    Rodrigues-Krause, J.2    O'Hagan, C.3    De Vito, G.4    Boreham, C.5    Susta, D.6    Newsholme, P.7    Murphy, C.8
  • 80
    • 80555143103 scopus 로고    scopus 로고
    • L-arginine is essential for pancreatic beta-cell functional integrity, metabolism and defense from inflammatory challenge
    • Krause MS, McClenaghan NH, Flatt PR, de Bittencourt PI, Murphy C, Newsholme P: L-arginine is essential for pancreatic beta-cell functional integrity, metabolism and defense from inflammatory challenge. J Endocrinol 2011, 211:87-97.
    • (2011) J Endocrinol , vol.211 , pp. 87-97
    • Krause, M.S.1    McClenaghan, N.H.2    Flatt, P.R.3    de Bittencourt, P.I.4    Murphy, C.5    Newsholme, P.6
  • 81
    • 71449102361 scopus 로고    scopus 로고
    • Exercise and possible molecular mechanisms of protection from vascular disease and diabetes: the central role of ROS and nitric oxide
    • Newsholme P, Homem De Bittencourt PI, OH C, De Vito G, Murphy C, Krause MS: Exercise and possible molecular mechanisms of protection from vascular disease and diabetes: the central role of ROS and nitric oxide. Clin Sci (Lond) 2009, 118:341-349.
    • (2009) Clin Sci (Lond) , vol.118 , pp. 341-349
    • Newsholme, P.1    Bittencourt, D.H.P.I.2    Oh, C.3    De Vito, G.4    Murphy, C.5    Krause, M.S.6
  • 82
    • 33751161061 scopus 로고    scopus 로고
    • Beneficial effects of a long-term oral L-arginine treatment added to a hypocaloric diet and exercise training program in obese, insulin-resistant type 2 diabetic patients
    • Lucotti P, Setola E, Monti LD, Galluccio E, Costa S, Sandoli EP, Fermo I, Rabaiotti G, Gatti R, Piatti P: Beneficial effects of a long-term oral L-arginine treatment added to a hypocaloric diet and exercise training program in obese, insulin-resistant type 2 diabetic patients. Am J Physiol Endocrinol Metab 2006, 291:E906-E912.
    • (2006) Am J Physiol Endocrinol Metab , vol.291 , pp. E906-E912
    • Lucotti, P.1    Setola, E.2    Monti, L.D.3    Galluccio, E.4    Costa, S.5    Sandoli, E.P.6    Fermo, I.7    Rabaiotti, G.8    Gatti, R.9    Piatti, P.10
  • 83
    • 84879551057 scopus 로고    scopus 로고
    • Effects of L-arginine supplementation on blood flow, oxidative stress status and exercise responses in young adults with uncomplicated type I diabetes
    • Fayh AP, Krause M, Rodrigues-Krause J, Ribeiro JL, Ribeiro JP, Friedman R, Moreira JC, Reischak-Oliveira A: Effects of L-arginine supplementation on blood flow, oxidative stress status and exercise responses in young adults with uncomplicated type I diabetes. Eur J Nutr 2013, 52:975-983.
    • (2013) Eur J Nutr , vol.52 , pp. 975-983
    • Fayh, A.P.1    Krause, M.2    Rodrigues-Krause, J.3    Ribeiro, J.L.4    Ribeiro, J.P.5    Friedman, R.6    Moreira, J.C.7    Reischak-Oliveira, A.8
  • 84
    • 77950670926 scopus 로고    scopus 로고
    • Arginine and ornithine supplementation increases growth hormone and insulin-like growth factor-1 serum levels after heavy-resistance exercise in strength-trained athletes
    • Zajac A, Poprzecki S, Zebrowska A, Chalimoniuk M, Langfort J: Arginine and ornithine supplementation increases growth hormone and insulin-like growth factor-1 serum levels after heavy-resistance exercise in strength-trained athletes. J Strength Cond Res 2010, 24:1082-1090.
    • (2010) J Strength Cond Res , vol.24 , pp. 1082-1090
    • Zajac, A.1    Poprzecki, S.2    Zebrowska, A.3    Chalimoniuk, M.4    Langfort, J.5
  • 86
    • 33845388678 scopus 로고    scopus 로고
    • Effects of L-arginine supplementation on exercise metabolism
    • McConell GK: Effects of L-arginine supplementation on exercise metabolism. Curr Opin Clin Nutr Metab Care 2007, 10:46-51.
    • (2007) Curr Opin Clin Nutr Metab Care , vol.10 , pp. 46-51
    • McConell, G.K.1
  • 88
    • 79960089497 scopus 로고    scopus 로고
    • Acute arginine supplementation fails to improve muscle endurance or affect blood pressure responses to resistance training
    • Greer BK, Jones BT: Acute arginine supplementation fails to improve muscle endurance or affect blood pressure responses to resistance training. J Strength Cond Res 2011, 25:1789-1794.
    • (2011) J Strength Cond Res , vol.25 , pp. 1789-1794
    • Greer, B.K.1    Jones, B.T.2
  • 89
    • 79251475599 scopus 로고    scopus 로고
    • Bolus arginine supplementation affects neither muscle blood flow nor muscle protein synthesis in young men at rest or after resistance exercise
    • Tang JE, Lysecki PJ, Manolakos JJ, MacDonald MJ, Tarnopolsky MA, Phillips SM: Bolus arginine supplementation affects neither muscle blood flow nor muscle protein synthesis in young men at rest or after resistance exercise. J Nutr 2011, 141:195-200.
    • (2011) J Nutr , vol.141 , pp. 195-200
    • Tang, J.E.1    Lysecki, P.J.2    Manolakos, J.J.3    MacDonald, M.J.4    Tarnopolsky, M.A.5    Phillips, S.M.6
  • 90
    • 84862224296 scopus 로고    scopus 로고
    • Acute L-arginine alpha ketoglutarate supplementation fails to improve muscular performance in resistance trained and untrained men
    • Wax B, Kavazis AN, Webb HE, Brown SP: Acute L-arginine alpha ketoglutarate supplementation fails to improve muscular performance in resistance trained and untrained men. J Int Soc Sports Nutr 2012, 9:17.
    • (2012) J Int Soc Sports Nutr , vol.9 , pp. 17
    • Wax, B.1    Kavazis, A.N.2    Webb, H.E.3    Brown, S.P.4
  • 91
    • 0032880516 scopus 로고    scopus 로고
    • Nitric oxide synthase inhibition reduces leg glucose uptake but not blood flow during dynamic exercise in humans
    • Bradley SJ, Kingwell BA, McConell GK: Nitric oxide synthase inhibition reduces leg glucose uptake but not blood flow during dynamic exercise in humans. Diabetes 1999, 48:1815-1821.
    • (1999) Diabetes , vol.48 , pp. 1815-1821
    • Bradley, S.J.1    Kingwell, B.A.2    McConell, G.K.3
  • 92
    • 0034995753 scopus 로고    scopus 로고
    • L-arginine in the management of cardiovascular diseases
    • Cheng JW, Baldwin SN: L-arginine in the management of cardiovascular diseases. Ann Pharmacother 2001, 35:755-764.
    • (2001) Ann Pharmacother , vol.35 , pp. 755-764
    • Cheng, J.W.1    Baldwin, S.N.2
  • 93
    • 0028946553 scopus 로고
    • Glaxo/MRS Young Investigator Prize. Endothelium-mediated vascular function in insulin-dependent diabetes mellitus
    • Poston L, Taylor PD: Glaxo/MRS Young Investigator Prize. Endothelium-mediated vascular function in insulin-dependent diabetes mellitus. Clin Sci (Lond) 1995, 88:245-255.
    • (1995) Clin Sci (Lond) , vol.88 , pp. 245-255
    • Poston, L.1    Taylor, P.D.2
  • 94
    • 0017182863 scopus 로고
    • Endogenous prostaglandins as local regulators of blood flow in man: effect of indomethacin on reactive and functional hyperaemia
    • Kilbom A, Wennmalm A: Endogenous prostaglandins as local regulators of blood flow in man: effect of indomethacin on reactive and functional hyperaemia. J Physiol 1976, 257:109-121.
    • (1976) J Physiol , vol.257 , pp. 109-121
    • Kilbom, A.1    Wennmalm, A.2
  • 95
    • 85047675349 scopus 로고
    • Effect of aspirin and indomethacin on exercise-induced changes in blood pressure and limb blood flow in normal volunteers
    • Cowley AJ, Stainer K, Rowley JM, Wilcox RG: Effect of aspirin and indomethacin on exercise-induced changes in blood pressure and limb blood flow in normal volunteers. Cardiovasc Res 1985, 19:177-180.
    • (1985) Cardiovasc Res , vol.19 , pp. 177-180
    • Cowley, A.J.1    Stainer, K.2    Rowley, J.M.3    Wilcox, R.G.4
  • 98
    • 20644461532 scopus 로고    scopus 로고
    • Influence of chronic supplementation of arginine aspartate in endurance athletes on performance and substrate metabolism-a randomized, double-blind, placebo-controlled study
    • Abel T, Knechtle B, Perret C, Eser P, von Arx P, Knecht H: Influence of chronic supplementation of arginine aspartate in endurance athletes on performance and substrate metabolism-a randomized, double-blind, placebo-controlled study. Int J Sports Med 2005, 26:344-349.
    • (2005) Int J Sports Med , vol.26 , pp. 344-349
    • Abel, T.1    Knechtle, B.2    Perret, C.3    Eser, P.4    von Arx, P.5    Knecht, H.6
  • 102
    • 84873802152 scopus 로고    scopus 로고
    • Does branched-chain amino acids supplementation modulate skeletal muscle remodeling through inflammation modulation? Possible mechanisms of action
    • Nicastro H, da Luz CR, Chaves DF, Bechara LR, Voltarelli VA, Rogero MM, Lancha AH Jr: Does branched-chain amino acids supplementation modulate skeletal muscle remodeling through inflammation modulation? Possible mechanisms of action. J NutrMetab 2012, 2012:136937.
    • (2012) J NutrMetab , vol.2012 , pp. 136937
    • Nicastro, H.1    da Luz, C.R.2    Chaves, D.F.3    Bechara, L.R.4    Voltarelli, V.A.5    Rogero, M.M.6    Lancha, A.H.7
  • 103
    • 50249099679 scopus 로고    scopus 로고
    • Is there a common mechanism linking muscle wasting in various disease types?
    • Tisdale MJ: Is there a common mechanism linking muscle wasting in various disease types? Curr Opin Support Palliat Care 2007, 1:287-292.
    • (2007) Curr Opin Support Palliat Care , vol.1 , pp. 287-292
    • Tisdale, M.J.1
  • 105
    • 33645996993 scopus 로고    scopus 로고
    • Effects of leucine supplementation on the body composition and protein status of rats submitted to food restriction
    • Donato J Jr, Pedrosa RG, Cruzat VF, Pires IS, Tirapegui J: Effects of leucine supplementation on the body composition and protein status of rats submitted to food restriction. Nutrition 2006, 22:520-527.
    • (2006) Nutrition , vol.22 , pp. 520-527
    • Donato, J.1    Pedrosa, R.G.2    Cruzat, V.F.3    Pires, I.S.4    Tirapegui, J.5
  • 106
    • 0026729002 scopus 로고
    • Role of leucine and other amino acids in regulating protein metabolism in vivo
    • Frexes-Steed M, Lacy DB, Collins J, Abumrad NN: Role of leucine and other amino acids in regulating protein metabolism in vivo. Am J Physiol 1992, 262:E925-E935.
    • (1992) Am J Physiol , vol.262 , pp. E925-E935
    • Frexes-Steed, M.1    Lacy, D.B.2    Collins, J.3    Abumrad, N.N.4
  • 108
    • 0034880489 scopus 로고    scopus 로고
    • BCAA intake affects protein metabolism in muscle after but not during exercise in humans
    • Blomstrand E, Saltin B: BCAA intake affects protein metabolism in muscle after but not during exercise in humans. Am J Physiol Endocrinol Metab 2001, 281:E365-E374.
    • (2001) Am J Physiol Endocrinol Metab , vol.281 , pp. E365-E374
    • Blomstrand, E.1    Saltin, B.2
  • 109
    • 84868134948 scopus 로고    scopus 로고
    • Dietary protein requirements and adaptive advantages in athletes
    • Phillips SM: Dietary protein requirements and adaptive advantages in athletes. Br J Nutr 2012, 108(Suppl 2):S158-S167.
    • (2012) Br J Nutr , vol.108 , pp. S158-S167
    • Phillips, S.M.1
  • 112
    • 33747056842 scopus 로고    scopus 로고
    • Effect of chronic supplementation with branched-chain amino acids on the performance and hepatic and muscle glycogen content in trained rats
    • de Araujo JA, Falavigna G, Rogero MM, Pires ISO, Pedrosa RG, Castro IA, Donato J, Tirapegui J: Effect of chronic supplementation with branched-chain amino acids on the performance and hepatic and muscle glycogen content in trained rats. Life Sci 2006, 79:1343-1348.
    • (2006) Life Sci , vol.79 , pp. 1343-1348
    • de Araujo, J.A.1    Falavigna, G.2    Rogero, M.M.3    Pires, I.S.O.4    Pedrosa, R.G.5    Castro, I.A.6    Donato, J.7    Tirapegui, J.8
  • 114
    • 84878795720 scopus 로고    scopus 로고
    • Additional effects of taurine on the benefits of BCAA intake for the delayed-onset muscle soreness and muscle damage induced by high-intensity eccentric exercise
    • Ra SG, Miyazaki T, Ishikura K, Nagayama H, Suzuki T, Maeda S, Ito M, Matsuzaki Y, Ohmori H: Additional effects of taurine on the benefits of BCAA intake for the delayed-onset muscle soreness and muscle damage induced by high-intensity eccentric exercise. Adv Exp Med Biol 2013, 776:179-187.
    • (2013) Adv Exp Med Biol , vol.776 , pp. 179-187
    • Ra, S.G.1    Miyazaki, T.2    Ishikura, K.3    Nagayama, H.4    Suzuki, T.5    Maeda, S.6    Ito, M.7    Matsuzaki, Y.8    Ohmori, H.9
  • 115
    • 84860439210 scopus 로고    scopus 로고
    • Interplay between lipids and branched-chain amino acids in development of insulin resistance
    • Newgard CB: Interplay between lipids and branched-chain amino acids in development of insulin resistance. Cell Metab 2012, 15:606-614.
    • (2012) Cell Metab , vol.15 , pp. 606-614
    • Newgard, C.B.1
  • 116
    • 84872352357 scopus 로고    scopus 로고
    • A-Z of nutritional supplements: dietary supplements, sports nutrition foods and ergogenic aids for health and performance: Part 43
    • Ranchordas MK, Burd NA, Godfrey RJ, Senchina DS, Stear SJ, Burke LM, Castell LM: A-Z of nutritional supplements: dietary supplements, sports nutrition foods and ergogenic aids for health and performance: Part 43. Br J Sports Med 2013, 47:399-400.
    • (2013) Br J Sports Med , vol.47 , pp. 399-400
    • Ranchordas, M.K.1    Burd, N.A.2    Godfrey, R.J.3    Senchina, D.S.4    Stear, S.J.5    Burke, L.M.6    Castell, L.M.7
  • 117
    • 3042686006 scopus 로고    scopus 로고
    • Therapeutic applications of whey protein
    • Marshall K: Therapeutic applications of whey protein. Altern Med Rev 2004, 9:136-156.
    • (2004) Altern Med Rev , vol.9 , pp. 136-156
    • Marshall, K.1
  • 118
    • 40749129588 scopus 로고    scopus 로고
    • Whey proteins in the regulation of food intake and satiety
    • Luhovyy BL, Akhavan T, Anderson GH: Whey proteins in the regulation of food intake and satiety. J Am Coll Nutr 2007, 26:704S-712S.
    • (2007) J Am Coll Nutr , vol.26 , pp. 704S-712S
    • Luhovyy, B.L.1    Akhavan, T.2    Anderson, G.H.3
  • 119
    • 84886811121 scopus 로고    scopus 로고
    • Quality assurance issues in the use of dietary supplements, with special reference to protein supplements
    • Maughan RJ: Quality assurance issues in the use of dietary supplements, with special reference to protein supplements. J Nutr 2013, 143:1843S-1847S.
    • (2013) J Nutr , vol.143 , pp. 1843S-1847S
    • Maughan, R.J.1
  • 121
    • 0038045562 scopus 로고    scopus 로고
    • Functional properties of whey, whey components, and essential amino acids: mechanisms underlying health benefits for active people (review)
    • Ha E, Zemel MB: Functional properties of whey, whey components, and essential amino acids: mechanisms underlying health benefits for active people (review). J Nutr Biochem 2003, 14:251-258.
    • (2003) J Nutr Biochem , vol.14 , pp. 251-258
    • Ha, E.1    Zemel, M.B.2
  • 124
    • 80052591726 scopus 로고    scopus 로고
    • Increased consumption of dairy foods and protein during diet- and exercise-induced weight loss promotes fat mass loss and lean mass gain in overweight and obese premenopausal women
    • Josse AR, Atkinson SA, Tarnopolsky MA, Phillips SM: Increased consumption of dairy foods and protein during diet- and exercise-induced weight loss promotes fat mass loss and lean mass gain in overweight and obese premenopausal women. J Nutr 2011, 141:1626-1634.
    • (2011) J Nutr , vol.141 , pp. 1626-1634
    • Josse, A.R.1    Atkinson, S.A.2    Tarnopolsky, M.A.3    Phillips, S.M.4
  • 125
    • 84866139022 scopus 로고    scopus 로고
    • Greater stimulation of myofibrillar protein synthesis with ingestion of whey protein isolate v. micellar casein at rest and after resistance exercise in elderly men
    • Burd NA, Yang Y, Moore DR, Tang JE, Tarnopolsky MA, Phillips SM: Greater stimulation of myofibrillar protein synthesis with ingestion of whey protein isolate v. micellar casein at rest and after resistance exercise in elderly men. Br J Nutr 2012, 108:958-962.
    • (2012) Br J Nutr , vol.108 , pp. 958-962
    • Burd, N.A.1    Yang, Y.2    Moore, D.R.3    Tang, J.E.4    Tarnopolsky, M.A.5    Phillips, S.M.6
  • 126
    • 69749123362 scopus 로고    scopus 로고
    • Ingestion of whey hydrolysate, casein, or soy protein isolate: effects on mixed muscle protein synthesis at rest and following resistance exercise in young men
    • Tang JE, Moore DR, Kujbida GW, Tarnopolsky MA, Phillips SM: Ingestion of whey hydrolysate, casein, or soy protein isolate: effects on mixed muscle protein synthesis at rest and following resistance exercise in young men. J Appl Physiol 2009, 107:987-992.
    • (2009) J Appl Physiol , vol.107 , pp. 987-992
    • Tang, J.E.1    Moore, D.R.2    Kujbida, G.W.3    Tarnopolsky, M.A.4    Phillips, S.M.5
  • 127
    • 0034835967 scopus 로고    scopus 로고
    • The effect of whey protein supplementation with and without creatine monohydrate combined with resistance training on lean tissue mass and muscle strength
    • Burke DG, Chilibeck PD, Davidson KS, Candow DG, Farthing J, Smith-Palmer T: The effect of whey protein supplementation with and without creatine monohydrate combined with resistance training on lean tissue mass and muscle strength. Int J Sport Nutr Exerc Metab 2001, 11:349-364.
    • (2001) Int J Sport Nutr Exerc Metab , vol.11 , pp. 349-364
    • Burke, D.G.1    Chilibeck, P.D.2    Davidson, K.S.3    Candow, D.G.4    Farthing, J.5    Smith-Palmer, T.6
  • 128
    • 0032821243 scopus 로고    scopus 로고
    • Effect of supplementation with a cysteine donor on muscular performance
    • Lands LC, Grey VL, Smountas AA: Effect of supplementation with a cysteine donor on muscular performance. J Appl Physiol 1999, 87:1381-1385.
    • (1999) J Appl Physiol , vol.87 , pp. 1381-1385
    • Lands, L.C.1    Grey, V.L.2    Smountas, A.A.3
  • 130
    • 34547855551 scopus 로고    scopus 로고
    • Consumption of fat-free fluid milk after resistance exercise promotes greater lean mass accretion than does consumption of soy or carbohydrate in young, novice, male weightlifters
    • Hartman JW, Tang JE, Wilkinson SB, Tarnopolsky MA, Lawrence RL, Fullerton AV, Phillips SM: Consumption of fat-free fluid milk after resistance exercise promotes greater lean mass accretion than does consumption of soy or carbohydrate in young, novice, male weightlifters. Am J Clin Nutr 2007, 86:373-381.
    • (2007) Am J Clin Nutr , vol.86 , pp. 373-381
    • Hartman, J.W.1    Tang, J.E.2    Wilkinson, S.B.3    Tarnopolsky, M.A.4    Lawrence, R.L.5    Fullerton, A.V.6    Phillips, S.M.7


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