L-Arginine is essential for pancreatic β-cell functional integrity, metabolism and defense from inflammatory challenge

Journal of Endocrinology

Volumn 211, Issue 1, 2011, Pages 87-97

  Krause, Mauricio S ^a,b   Mcclenaghan, Neville H ^c   Flatt, Peter R ^c   de Bittencourt, Paulo I Homem ^d   Murphy, Colin ^a   Newsholme, Philip ^b  

^a DUBLIN INSTITUTE OF TECHNOLOGY   (Ireland)

^b UNIVERSITY COLLEGE DUBLIN   (Ireland)

^c UNIVERSITY OF ULSTER   (United Kingdom)

^d FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; GAMMA INTERFERON; GLUTAMIC ACID; GLUTAMINE; GLUTATHIONE; GLUTATHIONE DISULFIDE; HEAT SHOCK PROTEIN 72; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; LACTIC ACID; NITRIC OXIDE; SUPEROXIDE; TUMOR NECROSIS FACTOR ALPHA; UREA; AMP ACTIVATED PROTEIN KINASE KINASE; AMP-ACTIVATED PROTEIN KINASE KINASE; CYTOKINE; INSULIN; NITRITE; PROTEIN KINASE;

ANIMAL CELL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CELL CLONE; CELL VIABILITY; GLUCOSE INTAKE; INFLAMMATION; INSULIN RELEASE; METABOLISM; MOUSE; NONHUMAN; PANCREAS ISLET CELL FUNCTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; STIMULUS SECRETION COUPLING; ANIMAL; ANIMAL MODEL; CELL CULTURE; CELL LINE; CELL SURVIVAL; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; OXIDATION REDUCTION REACTION; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PATHOPHYSIOLOGY; PHYSIOLOGY; SECRETION;

ANIMALS; ARGININE; CELL LINE; CELL SURVIVAL; CELLS, CULTURED; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTAMIC ACID; GLUTATHIONE; GLUTATHIONE DISULFIDE; HSP72 HEAT-SHOCK PROTEINS; INFLAMMATION; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; MODELS, ANIMAL; NITRIC OXIDE SYNTHASE TYPE II; NITRITES; OXIDATION-REDUCTION; PROTEIN KINASES; RATS; SUPEROXIDES; UREA;

EID: 80555143103     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1530/JOE-11-0236     Document Type: Article

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