-
2
-
-
0021175739
-
A 45-kDa human T-cell membrane glycoprotein functions in the regulation of cell proliferative responses
-
Gmünder H, Lesslauer W. A 45-kDa human T-cell membrane glycoprotein functions in the regulation of cell proliferative responses. Eur J Biochem (1984) 142:153-60. doi:10.1111/j.1432-1033.1984.tb08263.x
-
(1984)
Eur J Biochem
, vol.142
, pp. 153-160
-
-
Gmünder, H.1
Lesslauer, W.2
-
3
-
-
0000324490
-
CD28 activation pathway regulates the production of multiple T-cell-derived lymphokines/cytokines
-
Thompson CB, Lindsten T, Ledbetter JA, Kunkel SL, Young HA, Emerson SG, et al. CD28 activation pathway regulates the production of multiple T-cell-derived lymphokines/cytokines. Proc Natl Acad Sci U S A (1989) 86:1333-7. doi:10.1073/pnas.86.4.1333
-
(1989)
Proc Natl Acad Sci U S A
, vol.86
, pp. 1333-1337
-
-
Thompson, C.B.1
Lindsten, T.2
Ledbetter, J.A.3
Kunkel, S.L.4
Young, H.A.5
Emerson, S.G.6
-
4
-
-
0028484545
-
CTLA-4 can function as a negative regulator of T cell activation
-
Walunas TL, Lenschow DJ, Bakker CY, Linsley PS, Freeman GJ, Green JM, et al. CTLA-4 can function as a negative regulator of T cell activation. Immunity (1994) 1:405-13. doi:10.1016/1074-7613(94)90071-X
-
(1994)
Immunity
, vol.1
, pp. 405-413
-
-
Walunas, T.L.1
Lenschow, D.J.2
Bakker, C.Y.3
Linsley, P.S.4
Freeman, G.J.5
Green, J.M.6
-
5
-
-
84967205692
-
CD28 costimulation: from mechanism to therapy
-
Esensten JH, Helou YA, Chopra G, Weiss A, Bluestone JA. CD28 costimulation: from mechanism to therapy. Immunity (2016) 44:973-88. doi:10.1016/j.immuni.2016.04.020
-
(2016)
Immunity
, vol.44
, pp. 973-988
-
-
Esensten, J.H.1
Helou, Y.A.2
Chopra, G.3
Weiss, A.4
Bluestone, J.A.5
-
6
-
-
84966762527
-
Costimulatory and coinhibitory receptor pathways in infectious disease
-
Attanasio J, Wherry EJ. Costimulatory and coinhibitory receptor pathways in infectious disease. Immunity (2016) 44:1052-68. doi:10.1016/j.immuni.2016.04.022
-
(2016)
Immunity
, vol.44
, pp. 1052-1068
-
-
Attanasio, J.1
Wherry, E.J.2
-
7
-
-
84966738229
-
Coinhibitory pathways in the B7-CD28 ligand-receptor family
-
Schildberg FA, Klein SR, Freeman GJ, Sharpe AH. Coinhibitory pathways in the B7-CD28 ligand-receptor family. Immunity (2016) 44:955-72. doi:10.1016/j.immuni.2016.05.002
-
(2016)
Immunity
, vol.44
, pp. 955-972
-
-
Schildberg, F.A.1
Klein, S.R.2
Freeman, G.J.3
Sharpe, A.H.4
-
8
-
-
0033590502
-
ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28
-
Hutloff A, Dittrich AM, Beier KC, Eljaschewitsch B, Anagnostopoulos I, Kroczek RA. ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28. Nature (1999) 397:263-6. doi:10.1038/16717
-
(1999)
Nature
, vol.397
, pp. 263-266
-
-
Hutloff, A.1
Dittrich, A.M.2
Beier, K.C.3
Eljaschewitsch, B.4
Anagnostopoulos, I.5
Kroczek, R.A.6
-
9
-
-
0033999501
-
Molecular cloning and characterization of murine ICOS and identification of B7h as ICOS ligand
-
Mages HW, Hutloff A, Heuck C, Büchner K, Himmelbauer H, Oliveri F, et al. Molecular cloning and characterization of murine ICOS and identification of B7h as ICOS ligand. Eur J Immunol (2000) 30:1040-7. doi:10.1002/(SICI)1521-4141(200004)30:4<1040::AID-IMMU1040>3.0.CO;2-6
-
(2000)
Eur J Immunol
, vol.30
, pp. 1040-1047
-
-
Mages, H.W.1
Hutloff, A.2
Heuck, C.3
Büchner, K.4
Himmelbauer, H.5
Oliveri, F.6
-
10
-
-
0142259712
-
Unifying concepts in CD28, ICOS and CTLA4 co-receptor signalling
-
Rudd CE, Schneider H. Unifying concepts in CD28, ICOS and CTLA4 co-receptor signalling. Nat Rev Immunol (2003) 3:544-56. doi:10.1038/nri1131
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 544-556
-
-
Rudd, C.E.1
Schneider, H.2
-
11
-
-
0034327808
-
Mouse inducible costimulatory molecule (ICOS) expression is enhanced by CD28 costimulation and regulates differentiation of CD4+ T cells
-
McAdam AJ, Chang TT, Lumelsky AE, Greenfield EA, Boussiotis VA, Duke-Cohan JS, et al. Mouse inducible costimulatory molecule (ICOS) expression is enhanced by CD28 costimulation and regulates differentiation of CD4+ T cells. J Immunol (2000) 165:5035-40. doi:10.4049/jimmunol.165.9.5035
-
(2000)
J Immunol
, vol.165
, pp. 5035-5040
-
-
McAdam, A.J.1
Chang, T.T.2
Lumelsky, A.E.3
Greenfield, E.A.4
Boussiotis, V.A.5
Duke-Cohan, J.S.6
-
12
-
-
0033576707
-
T-cell co-stimulation through B7RP-1 and ICOS
-
Yoshinaga SK, Whoriskey JS, Khare SD, Sarmiento U, Guo J, Horan T, et al. T-cell co-stimulation through B7RP-1 and ICOS. Nature (1999) 402:827-32. doi:10.1038/45582
-
(1999)
Nature
, vol.402
, pp. 827-832
-
-
Yoshinaga, S.K.1
Whoriskey, J.S.2
Khare, S.D.3
Sarmiento, U.4
Guo, J.5
Horan, T.6
-
13
-
-
14944358732
-
A distinct role for ICOS-mediated co-stimulatory signaling in CD4+ and CD8+ T cell subsets
-
Watanabe M, Hara Y, Tanabe K, Toma H, Abe R. A distinct role for ICOS-mediated co-stimulatory signaling in CD4+ and CD8+ T cell subsets. Int Immunol (2005) 17:269-78. doi:10.1093/intimm/dxh206
-
(2005)
Int Immunol
, vol.17
, pp. 269-278
-
-
Watanabe, M.1
Hara, Y.2
Tanabe, K.3
Toma, H.4
Abe, R.5
-
14
-
-
0035988233
-
A co-stimulatory molecule on activated T cells, H4/ICOS, delivers specific signals in T(h) cells and regulates their responses
-
Arimura Y, Kato H, Dianzani U, Okamoto T, Kamekura S, Buonfiglio D, et al. A co-stimulatory molecule on activated T cells, H4/ICOS, delivers specific signals in T(h) cells and regulates their responses. Int Immunol (2002) 14:555-66. doi:10.1093/intimm/dxf022
-
(2002)
Int Immunol
, vol.14
, pp. 555-566
-
-
Arimura, Y.1
Kato, H.2
Dianzani, U.3
Okamoto, T.4
Kamekura, S.5
Buonfiglio, D.6
-
15
-
-
73949090666
-
Inducible costimulator promotes helper T-cell differentiation through phosphoinositide 3-kinase
-
Gigoux M, Shang J, Pak Y, Xu M, Choe J, Mak TW, et al. Inducible costimulator promotes helper T-cell differentiation through phosphoinositide 3-kinase. Proc Natl Acad Sci U S A (2009) 106:20371-6. doi:10.1073/pnas.0911573106
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 20371-20376
-
-
Gigoux, M.1
Shang, J.2
Pak, Y.3
Xu, M.4
Choe, J.5
Mak, T.W.6
-
16
-
-
0034651694
-
Cutting edge: identification of GL50, a novel B7-like protein that functionally binds to ICOS receptor
-
Ling V, Wu PW, Finnerty HF, Bean KM, Spaulding V, Fouser LA, et al. Cutting edge: identification of GL50, a novel B7-like protein that functionally binds to ICOS receptor. J Immunol (2000) 164:1653-7. doi:10.4049/jimmunol.164.4.1653
-
(2000)
J Immunol
, vol.164
, pp. 1653-1657
-
-
Ling, V.1
Wu, P.W.2
Finnerty, H.F.3
Bean, K.M.4
Spaulding, V.5
Fouser, L.A.6
-
17
-
-
0034193043
-
Characterization of human inducible costimulator ligand expression and function
-
Aicher A, Hayden-Ledbetter M, Brady WA, Pezzutto A, Richter G, Magaletti D, et al. Characterization of human inducible costimulator ligand expression and function. J Immunol (2000) 164:4689-96. doi:10.4049/jimmunol.164.9.4689
-
(2000)
J Immunol
, vol.164
, pp. 4689-4696
-
-
Aicher, A.1
Hayden-Ledbetter, M.2
Brady, W.A.3
Pezzutto, A.4
Richter, G.5
Magaletti, D.6
-
18
-
-
0027937702
-
Complementarity determining region 1 (CDR1)-and CDR3-analogous regions in CTLA-4 and CD28 determine the binding to B7-1
-
Peach RJ, Bajorath J, Brady W, Leytze G, Greene J, Naemura J, et al. Complementarity determining region 1 (CDR1)-and CDR3-analogous regions in CTLA-4 and CD28 determine the binding to B7-1. J Exp Med (1994) 180:2049-58. doi:10.1084/jem.180.6.2049
-
(1994)
J Exp Med
, vol.180
, pp. 2049-2058
-
-
Peach, R.J.1
Bajorath, J.2
Brady, W.3
Leytze, G.4
Greene, J.5
Naemura, J.6
-
19
-
-
45949106108
-
Down-regulation of ICOS ligand by interaction with ICOS functions as a regulatory mechanism for immune responses
-
Watanabe M, Takagi Y, Kotani M, Hara Y, Inamine A, Hayashi K, et al. Down-regulation of ICOS ligand by interaction with ICOS functions as a regulatory mechanism for immune responses. J Immunol (2008) 180:5222-34. doi:10.4049/jimmunol.180.8.5222
-
(2008)
J Immunol
, vol.180
, pp. 5222-5234
-
-
Watanabe, M.1
Takagi, Y.2
Kotani, M.3
Hara, Y.4
Inamine, A.5
Hayashi, K.6
-
20
-
-
79961233459
-
Noncanonical NF-kappaB regulates inducible costimulator (ICOS) ligand expression and T follicular helper cell development
-
Hu H, Wu X, Jin W, Chang M, Cheng X, Sun S-C. Noncanonical NF-kappaB regulates inducible costimulator (ICOS) ligand expression and T follicular helper cell development. Proc Natl Acad Sci U S A (2011) 108:12827-32. doi:10.1073/pnas.1105774108
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 12827-12832
-
-
Hu, H.1
Wu, X.2
Jin, W.3
Chang, M.4
Cheng, X.5
Sun, S.-C.6
-
21
-
-
0033212778
-
B7h, a novel costimulatory homolog of B7.1 and B7.2, is induced by TNFalpha
-
Swallow MM, Wallin JJ, Sha WC. B7h, a novel costimulatory homolog of B7.1 and B7.2, is induced by TNFalpha. Immunity (1999) 11:423-32. doi:10.1016/S1074-7613(00)80117-X
-
(1999)
Immunity
, vol.11
, pp. 423-432
-
-
Swallow, M.M.1
Wallin, J.J.2
Sha, W.C.3
-
22
-
-
0033809736
-
Characterization of a new human B7-related protein: B7RP-1 is the ligand to the co-stimulatory protein ICOS
-
Yoshinaga SK, Zhang M, Pistillo J, Horan T, Khare SD, Miner K, et al. Characterization of a new human B7-related protein: B7RP-1 is the ligand to the co-stimulatory protein ICOS. Int Immunol (2000) 12:1439-47. doi:10.1093/intimm/12.10.1439
-
(2000)
Int Immunol
, vol.12
, pp. 1439-1447
-
-
Yoshinaga, S.K.1
Zhang, M.2
Pistillo, J.3
Horan, T.4
Khare, S.D.5
Miner, K.6
-
23
-
-
0037197828
-
ICOS-ligand, expressed on human endothelial cells, costimulates Th1 and Th2 cytokine secretion by memory CD4+ T cells
-
Khayyamian S, Hutloff A, Büchner K, Gräfe M, Henn V, Kroczek RA, et al. ICOS-ligand, expressed on human endothelial cells, costimulates Th1 and Th2 cytokine secretion by memory CD4+ T cells. Proc Natl Acad Sci U S A (2002) 99:6198-203. doi:10.1073/pnas.092576699
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 6198-6203
-
-
Khayyamian, S.1
Hutloff, A.2
Büchner, K.3
Gräfe, M.4
Henn, V.5
Kroczek, R.A.6
-
24
-
-
33645909564
-
The ICOS-ligand B7-H2, expressed on human type II alveolar epithelial cells, plays a role in the pulmonary host defense system
-
Qian X, Agematsu K, Freeman GJ, Tagawa Y-I, Sugane K, Hayashi T. The ICOS-ligand B7-H2, expressed on human type II alveolar epithelial cells, plays a role in the pulmonary host defense system. Eur J Immunol (2006) 36:906-18. doi:10.1002/eji.200535253
-
(2006)
Eur J Immunol
, vol.36
, pp. 906-918
-
-
Qian, X.1
Agematsu, K.2
Freeman, G.J.3
Tagawa, Y.-I.4
Sugane, K.5
Hayashi, T.6
-
25
-
-
0037015055
-
Modulation of TCR-induced transcriptional profiles by ligation of CD28, ICOS, and CTLA-4 receptors
-
Riley JL, Mao M, Kobayashi S, Biery M, Burchard J, Cavet G, et al. Modulation of TCR-induced transcriptional profiles by ligation of CD28, ICOS, and CTLA-4 receptors. Proc Natl Acad Sci U S A (2002) 99:11790-5. doi:10.1073/pnas.162359999
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 11790-11795
-
-
Riley, J.L.1
Mao, M.2
Kobayashi, S.3
Biery, M.4
Burchard, J.5
Cavet, G.6
-
26
-
-
0033696961
-
The CD28-related molecule ICOS is required for effective T cell-dependent immune responses
-
Coyle AJ, Lehar S, Lloyd C, Tian J, Delaney T, Manning S, et al. The CD28-related molecule ICOS is required for effective T cell-dependent immune responses. Immunity (2000) 13:95-105. doi:10.1016/S1074-7613(00)00011-X
-
(2000)
Immunity
, vol.13
, pp. 95-105
-
-
Coyle, A.J.1
Lehar, S.2
Lloyd, C.3
Tian, J.4
Delaney, T.5
Manning, S.6
-
27
-
-
49649098826
-
ICOS ligation recruits the p50alpha PI3K regulatory subunit to the immunological synapse
-
Fos C, Salles A, Lang V, Carrette F, Audebert S, Pastor S, et al. ICOS ligation recruits the p50alpha PI3K regulatory subunit to the immunological synapse. J Immunol (2008) 181:1969-77. doi:10.4049/jimmunol.181.3.1969
-
(2008)
J Immunol
, vol.181
, pp. 1969-1977
-
-
Fos, C.1
Salles, A.2
Lang, V.3
Carrette, F.4
Audebert, S.5
Pastor, S.6
-
28
-
-
84868528894
-
The PI3K/AKT/mTOR pathway as a therapeutic target in endometrial cancer
-
Slomovitz BM, Coleman RL. The PI3K/AKT/mTOR pathway as a therapeutic target in endometrial cancer. Clin Cancer Res (2012) 18:5856-64. doi:10.1158/1078-0432.CCR-12-0662
-
(2012)
Clin Cancer Res
, vol.18
, pp. 5856-5864
-
-
Slomovitz, B.M.1
Coleman, R.L.2
-
29
-
-
84920956940
-
A p85a-osteopontin axis couples the receptor ICOS to sustained Bcl-6 expression by follicular helper and regulatory T cells
-
Leavenworth JW, Verbinnen B, Yin J, Huang H, Cantor H. A p85a-osteopontin axis couples the receptor ICOS to sustained Bcl-6 expression by follicular helper and regulatory T cells. Nat Immunol (2015) 16:96-106. doi:10.1038/ni.3050
-
(2015)
Nat Immunol
, vol.16
, pp. 96-106
-
-
Leavenworth, J.W.1
Verbinnen, B.2
Yin, J.3
Huang, H.4
Cantor, H.5
-
30
-
-
0038545370
-
CD28 and inducible costimulatory protein Src homology 2 binding domains show distinct regulation of phosphatidylinositol 3-kinase, Bcl-xL, and IL-2 expression in primary human CD4 T lymphocytes
-
Parry RV, Rumbley CA, Vandenberghe LH, June CH, Riley JL. CD28 and inducible costimulatory protein Src homology 2 binding domains show distinct regulation of phosphatidylinositol 3-kinase, Bcl-xL, and IL-2 expression in primary human CD4 T lymphocytes. J Immunol (2003) 171:166-74. doi:10.4049/jimmunol.171.1.166
-
(2003)
J Immunol
, vol.171
, pp. 166-174
-
-
Parry, R.V.1
Rumbley, C.A.2
Vandenberghe, L.H.3
June, C.H.4
Riley, J.L.5
-
31
-
-
0037455064
-
A single amino acid alteration in cytoplasmic domain determines IL-2 promoter activation by ligation of CD28 but not inducible costimulator (ICOS)
-
Harada Y, Ohgai D, Watanabe R, Okano K, Koiwai O, Tanabe K, et al. A single amino acid alteration in cytoplasmic domain determines IL-2 promoter activation by ligation of CD28 but not inducible costimulator (ICOS). J Exp Med (2003) 197:257-62. doi:10.1084/jem.20021305
-
(2003)
J Exp Med
, vol.197
, pp. 257-262
-
-
Harada, Y.1
Ohgai, D.2
Watanabe, R.3
Okano, K.4
Koiwai, O.5
Tanabe, K.6
-
32
-
-
0035830778
-
Five isoforms of the phosphatidylinositol 3-kinase regulatory subunit exhibit different associations with receptor tyrosine kinases and their tyrosine phosphorylations
-
Inukai K, Funaki M, Anai M, Ogihara T, Katagiri H, Fukushima Y, et al. Five isoforms of the phosphatidylinositol 3-kinase regulatory subunit exhibit different associations with receptor tyrosine kinases and their tyrosine phosphorylations. FEBS Lett (2001) 490:32-8. doi:10.1016/S0014-5793(01)02132-9
-
(2001)
FEBS Lett
, vol.490
, pp. 32-38
-
-
Inukai, K.1
Funaki, M.2
Anai, M.3
Ogihara, T.4
Katagiri, H.5
Fukushima, Y.6
-
33
-
-
84879659016
-
Phosphatidylinositol 3-kinase-independent signaling pathways contribute to ICOS-mediated T cell costimulation in acute graft-versus-host disease in mice
-
Li J, Heinrichs J, Leconte J, Haarberg K, Semple K, Liu C, et al. Phosphatidylinositol 3-kinase-independent signaling pathways contribute to ICOS-mediated T cell costimulation in acute graft-versus-host disease in mice. J Immunol (2013) 191:200-7. doi:10.4049/jimmunol.1203485
-
(2013)
J Immunol
, vol.191
, pp. 200-207
-
-
Li, J.1
Heinrichs, J.2
Leconte, J.3
Haarberg, K.4
Semple, K.5
Liu, C.6
-
34
-
-
77958134778
-
Phosphoinositide 3-kinase activity in T cells regulates the magnitude of the germinal center reaction
-
Rolf J, Bell SE, Kovesdi D, Janas ML, Soond DR, Webb LMC, et al. Phosphoinositide 3-kinase activity in T cells regulates the magnitude of the germinal center reaction. J Immunol (2010) 185:4042-52. doi:10.4049/jimmunol.1001730
-
(2010)
J Immunol
, vol.185
, pp. 4042-4052
-
-
Rolf, J.1
Bell, S.E.2
Kovesdi, D.3
Janas, M.L.4
Soond, D.R.5
Webb, L.M.C.6
-
35
-
-
84965000305
-
A TRAF-like motif of the inducible costimulator ICOS controls development of germinal center TFH cells via the kinase TBK1
-
Pedros C, Zhang Y, Hu JK, Choi YS, Canonigo-Balancio AJ, Yates JR, et al. A TRAF-like motif of the inducible costimulator ICOS controls development of germinal center TFH cells via the kinase TBK1. Nat Immunol (2016) 17:825-33. doi:10.1038/ni.3463
-
(2016)
Nat Immunol
, vol.17
, pp. 825-833
-
-
Pedros, C.1
Zhang, Y.2
Hu, J.K.3
Choi, Y.S.4
Canonigo-Balancio, A.J.5
Yates, J.R.6
-
36
-
-
0033595893
-
How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex
-
Karin M. How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex. Oncogene (1999) 18:6867-74. doi:10.1038/sj.onc.1203219
-
(1999)
Oncogene
, vol.18
, pp. 6867-6874
-
-
Karin, M.1
-
37
-
-
0035804254
-
ICOS co-stimulatory receptor is essential for T-cell activation and function
-
Dong C, Juedes AE, Temann UA, Shresta S, Allison JP, Ruddle NH, et al. ICOS co-stimulatory receptor is essential for T-cell activation and function. Nature (2001) 409:97-101. doi:10.1038/35051100
-
(2001)
Nature
, vol.409
, pp. 97-101
-
-
Dong, C.1
Juedes, A.E.2
Temann, U.A.3
Shresta, S.4
Allison, J.P.5
Ruddle, N.H.6
-
38
-
-
0035804269
-
ICOS is essential for effective T-helper-cell responses
-
Tafuri A, Shahinian A, Bladt F, Yoshinaga SK, Jordana M, Wakeham A, et al. ICOS is essential for effective T-helper-cell responses. Nature (2001) 409:105-9. doi:10.1038/35051113
-
(2001)
Nature
, vol.409
, pp. 105-109
-
-
Tafuri, A.1
Shahinian, A.2
Bladt, F.3
Yoshinaga, S.K.4
Jordana, M.5
Wakeham, A.6
-
39
-
-
33746891247
-
B7RP-1-ICOS interactions are required for optimal infection-induced expansion of CD4+ Th1 and Th2 responses
-
Wilson EH, Zaph C, Mohrs M, Welcher A, Siu J, Artis D, et al. B7RP-1-ICOS interactions are required for optimal infection-induced expansion of CD4+ Th1 and Th2 responses. J Immunol (2006) 177:2365-72. doi:10.4049/jimmunol.177.4.2365
-
(2006)
J Immunol
, vol.177
, pp. 2365-2372
-
-
Wilson, E.H.1
Zaph, C.2
Mohrs, M.3
Welcher, A.4
Siu, J.5
Artis, D.6
-
40
-
-
0037371432
-
Inducible costimulatory molecule-B7-related protein 1 interactions are important for the clonal expansion and B cell helper functions of naive, Th1, and Th2 T cells
-
Smith KM, Brewer JM, Webb P, Coyle AJ, Gutierrez-Ramos C, Garside P. Inducible costimulatory molecule-B7-related protein 1 interactions are important for the clonal expansion and B cell helper functions of naive, Th1, and Th2 T cells. J Immunol (2003) 170:2310-5. doi:10.4049/jimmunol.170.5.2310
-
(2003)
J Immunol
, vol.170
, pp. 2310-2315
-
-
Smith, K.M.1
Brewer, J.M.2
Webb, P.3
Coyle, A.J.4
Gutierrez-Ramos, C.5
Garside, P.6
-
41
-
-
0017199306
-
Selective in vitro growth of T lymphocytes from normal human bone marrows
-
Morgan DA, Ruscetti FW, Gallo R. Selective in vitro growth of T lymphocytes from normal human bone marrows. Science (1976) 193:1007-8. doi:10.1126/science.181845
-
(1976)
Science
, vol.193
, pp. 1007-1008
-
-
Morgan, D.A.1
Ruscetti, F.W.2
Gallo, R.3
-
42
-
-
0036740602
-
ICOS and CD28 reversely regulate IL-10 on re-activation of human effector T cells with mature dendritic cells
-
Witsch EJ, Peiser M, Hutloff A, Büchner K, Dorner BG, Jonuleit H, et al. ICOS and CD28 reversely regulate IL-10 on re-activation of human effector T cells with mature dendritic cells. Eur J Immunol (2002) 32:2680-6. doi:10.1002/1521-4141(200209)32:9<2680::AID-IMMU2680>3.0.CO;2-6
-
(2002)
Eur J Immunol
, vol.32
, pp. 2680-2686
-
-
Witsch, E.J.1
Peiser, M.2
Hutloff, A.3
Büchner, K.4
Dorner, B.G.5
Jonuleit, H.6
-
43
-
-
79953037866
-
Impact of inducible co-stimulatory molecule (ICOS) on T-cell responses and protection against Mycobacterium tuberculosis infection
-
Nouailles G, Day TA, Kuhlmann S, Loewe D, Dorhoi A, Gamradt P, et al. Impact of inducible co-stimulatory molecule (ICOS) on T-cell responses and protection against Mycobacterium tuberculosis infection. Eur J Immunol (2011) 41:981-91. doi:10.1002/eji.201040608
-
(2011)
Eur J Immunol
, vol.41
, pp. 981-991
-
-
Nouailles, G.1
Day, T.A.2
Kuhlmann, S.3
Loewe, D.4
Dorhoi, A.5
Gamradt, P.6
-
44
-
-
77951628752
-
Th1 cytokine responses fail to effectively control Chlamydia lung infection in ICOS ligand knockout mice
-
Kadkhoda K, Wang S, Joyee AG, Fan Y, Yang J, Yang X. Th1 cytokine responses fail to effectively control Chlamydia lung infection in ICOS ligand knockout mice. J Immunol (2010) 184:3780-8. doi:10.4049/jimmunol.0901384
-
(2010)
J Immunol
, vol.184
, pp. 3780-3788
-
-
Kadkhoda, K.1
Wang, S.2
Joyee, A.G.3
Fan, Y.4
Yang, J.5
Yang, X.6
-
45
-
-
84871507876
-
Anti-chlamydial Th17 responses are controlled by the inducible costimulator partially through phosphoinositide 3-kinase signaling
-
Gao X, Gigoux M, Yang J, Leconte J, Yang X, Suh W-K. Anti-chlamydial Th17 responses are controlled by the inducible costimulator partially through phosphoinositide 3-kinase signaling. PLoS One (2012) 7:e52657. doi:10.1371/journal.pone.0052657
-
(2012)
PLoS One
, vol.7
-
-
Gao, X.1
Gigoux, M.2
Yang, J.3
Leconte, J.4
Yang, X.5
Suh, W.-K.6
-
46
-
-
34548480512
-
Differential CD28 and inducible costimulatory molecule signaling requirements for protective CD4+ T-cell-mediated immunity against genital tract Chlamydia trachomatis infection
-
Marks E, Verolin M, Stensson A, Lycke N. Differential CD28 and inducible costimulatory molecule signaling requirements for protective CD4+ T-cell-mediated immunity against genital tract Chlamydia trachomatis infection. Infect Immun (2007) 75:4638-47. doi:10.1128/IAI.00465-07
-
(2007)
Infect Immun
, vol.75
, pp. 4638-4647
-
-
Marks, E.1
Verolin, M.2
Stensson, A.3
Lycke, N.4
-
47
-
-
0037972475
-
Disruption of the ICOS-B7RP-1 costimulatory pathway leads to enhanced hepatic immunopathology and increased gamma interferon production by CD4 T cells in murine schistosomiasis
-
Rutitzky LI, Ozkaynak E, Rottman JB, Stadecker MJ. Disruption of the ICOS-B7RP-1 costimulatory pathway leads to enhanced hepatic immunopathology and increased gamma interferon production by CD4 T cells in murine schistosomiasis. Infect Immun (2003) 71:4040-4. doi:10.1128/IAI.71.7.4040-4044.2003
-
(2003)
Infect Immun
, vol.71
, pp. 4040-4044
-
-
Rutitzky, L.I.1
Ozkaynak, E.2
Rottman, J.B.3
Stadecker, M.J.4
-
48
-
-
84954091632
-
The costimulatory molecule ICOS regulates host Th1 and follicular Th cell differentiation in response to Plasmodium chabaudi chabaudi AS Infection
-
Wikenheiser DJ, Ghosh D, Kennedy B, Stumhofer JS. The costimulatory molecule ICOS regulates host Th1 and follicular Th cell differentiation in response to Plasmodium chabaudi chabaudi AS Infection. J Immunol (2016) 196:778-91. doi:10.4049/jimmunol.1403206
-
(2016)
J Immunol
, vol.196
, pp. 778-791
-
-
Wikenheiser, D.J.1
Ghosh, D.2
Kennedy, B.3
Stumhofer, J.S.4
-
49
-
-
31844435407
-
Role for inducible costimulator in control of Salmonella enterica serovar Typhimurium infection in mice
-
Vidric M, Bladt AT, Dianzani U, Watts TH. Role for inducible costimulator in control of Salmonella enterica serovar Typhimurium infection in mice. Infect Immun (2006) 74:1050-61. doi:10.1128/IAI.74.2.1050-1061.2006
-
(2006)
Infect Immun
, vol.74
, pp. 1050-1061
-
-
Vidric, M.1
Bladt, A.T.2
Dianzani, U.3
Watts, T.H.4
-
50
-
-
0037111417
-
Inducible costimulator protein controls the protective T cell response against Listeria monocytogenes
-
Mittrücker H-W, Kursar M, Köhler A, Yanagihara D, Yoshinaga SK, Kaufmann SHE. Inducible costimulator protein controls the protective T cell response against Listeria monocytogenes. J Immunol (2002) 169:5813-7. doi:10.4049/jimmunol.169.10.5813
-
(2002)
J Immunol
, vol.169
, pp. 5813-5817
-
-
Mittrücker, H.-W.1
Kursar, M.2
Köhler, A.3
Yanagihara, D.4
Yoshinaga, S.K.5
Kaufmann, S.H.E.6
-
51
-
-
0037100389
-
A role for inducible costimulator protein in the CD28-independent mechanism of resistance to Toxoplasma gondii
-
Villegas EN, Lieberman LA, Mason N, Blass SL, Zediak VP, Peach R, et al. A role for inducible costimulator protein in the CD28-independent mechanism of resistance to Toxoplasma gondii. J Immunol (2002) 169:937-43. doi:10.4049/jimmunol.169.2.937
-
(2002)
J Immunol
, vol.169
, pp. 937-943
-
-
Villegas, E.N.1
Lieberman, L.A.2
Mason, N.3
Blass, S.L.4
Zediak, V.P.5
Peach, R.6
-
52
-
-
0034600567
-
Inducible costimulator protein (ICOS) controls T helper cell subset polarization after virus and parasite infection
-
Kopf M, Coyle AJ, Schmitz N, Barner M, Oxenius A, Gallimore A, et al. Inducible costimulator protein (ICOS) controls T helper cell subset polarization after virus and parasite infection. J Exp Med (2000) 192:53-61. doi:10.1084/jem.192.1.53
-
(2000)
J Exp Med
, vol.192
, pp. 53-61
-
-
Kopf, M.1
Coyle, A.J.2
Schmitz, N.3
Barner, M.4
Oxenius, A.5
Gallimore, A.6
-
53
-
-
0036467340
-
Cutting edge: inducible costimulator protein regulates both Th1 and Th2 responses to cutaneous leishmaniasis
-
Greenwald RJ, McAdam AJ, Van der Woude D, Satoskar AR, Sharpe AH. Cutting edge: inducible costimulator protein regulates both Th1 and Th2 responses to cutaneous leishmaniasis. J Immunol (2002) 168:991-5. doi:10.4049/jimmunol.168.3.991
-
(2002)
J Immunol
, vol.168
, pp. 991-995
-
-
Greenwald, R.J.1
McAdam, A.J.2
Van der Woude, D.3
Satoskar, A.R.4
Sharpe, A.H.5
-
54
-
-
2142825777
-
Human T cell activation by costimulatory signal-deficient allogeneic cells induces inducible costimulator-expressing anergic T cells with regulatory cell activity
-
Vermeiren J, Ceuppens JL, Van Ghelue M, Witters P, Bullens D, Mages HW, et al. Human T cell activation by costimulatory signal-deficient allogeneic cells induces inducible costimulator-expressing anergic T cells with regulatory cell activity. J Immunol (2004) 172:5371-8. doi:10.4049/jimmunol.172.9.5371
-
(2004)
J Immunol
, vol.172
, pp. 5371-5378
-
-
Vermeiren, J.1
Ceuppens, J.L.2
Van Ghelue, M.3
Witters, P.4
Bullens, D.5
Mages, H.W.6
-
55
-
-
0036732461
-
Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity
-
Akbari O, Freeman GJ, Meyer EH, Greenfield EA, Chang TT, Sharpe AH, et al. Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity. Nat Med (2002) 8:1024-32. doi:10.1038/nm745
-
(2002)
Nat Med
, vol.8
, pp. 1024-1032
-
-
Akbari, O.1
Freeman, G.J.2
Meyer, E.H.3
Greenfield, E.A.4
Chang, T.T.5
Sharpe, A.H.6
-
56
-
-
0037455003
-
Expression of ICOS in vivo defines CD4+ effector T cells with high inflammatory potential and a strong bias for secretion of interleukin 10
-
Löhning M, Hutloff A, Kallinich T, Mages HW, Bonhagen K, Radbruch A, et al. Expression of ICOS in vivo defines CD4+ effector T cells with high inflammatory potential and a strong bias for secretion of interleukin 10. J Exp Med (2003) 197:181-93. doi:10.1084/jem.20020632
-
(2003)
J Exp Med
, vol.197
, pp. 181-193
-
-
Löhning, M.1
Hutloff, A.2
Kallinich, T.3
Mages, H.W.4
Bonhagen, K.5
Radbruch, A.6
-
57
-
-
84866170168
-
ICOS-expressing CD4 T cells induced via TLR4 in the nasal mucosa are capable of inhibiting experimental allergic asthma
-
Shalaby KH, Jo T, Nakada E, Allard-Coutu A, Tsuchiya K, Hirota N, et al. ICOS-expressing CD4 T cells induced via TLR4 in the nasal mucosa are capable of inhibiting experimental allergic asthma. J Immunol (2012) 189:2793-804. doi:10.4049/jimmunol.1201194
-
(2012)
J Immunol
, vol.189
, pp. 2793-2804
-
-
Shalaby, K.H.1
Jo, T.2
Nakada, E.3
Allard-Coutu, A.4
Tsuchiya, K.5
Hirota, N.6
-
58
-
-
84864823851
-
ICOS mediates the generation and function of CD4+CD25+Foxp3+ regulatory T cells conveying respiratory tolerance
-
Busse M, Krech M, Meyer-Bahlburg A, Hennig C, Hansen G. ICOS mediates the generation and function of CD4+CD25+Foxp3+ regulatory T cells conveying respiratory tolerance. J Immunol (2012) 189:1975-82. doi:10.4049/jimmunol.1103581
-
(2012)
J Immunol
, vol.189
, pp. 1975-1982
-
-
Busse, M.1
Krech, M.2
Meyer-Bahlburg, A.3
Hennig, C.4
Hansen, G.5
-
59
-
-
84874996294
-
ICOS controls Foxp3(+) regulatory T-cell expansion, maintenance and IL-10 production during helminth infection
-
Redpath SA, van der Werf N, Cervera AM, MacDonald AS, Gray D, Maizels RM, et al. ICOS controls Foxp3(+) regulatory T-cell expansion, maintenance and IL-10 production during helminth infection. Eur J Immunol (2013) 43:705-15. doi:10.1002/eji.201242794
-
(2013)
Eur J Immunol
, vol.43
, pp. 705-715
-
-
Redpath, S.A.1
van der Werf, N.2
Cervera, A.M.3
MacDonald, A.S.4
Gray, D.5
Maizels, R.M.6
-
60
-
-
0031882588
-
Potential role of B7-1 and CD28 molecules in immunosuppression in leprosy
-
Agrewala JN, Kumar B, Vohra H. Potential role of B7-1 and CD28 molecules in immunosuppression in leprosy. Clin Exp Immunol (1998) 111:56-63. doi:10.1046/j.1365-2249.1998.00463.x
-
(1998)
Clin Exp Immunol
, vol.111
, pp. 56-63
-
-
Agrewala, J.N.1
Kumar, B.2
Vohra, H.3
-
61
-
-
0035708538
-
Downmodulation of CD18 and CD86 on macrophages and VLA-4 on lymphocytes in experimental tuberculosis
-
Bonato VL, Medeiros AI, Lima VM, Dias AR, Faccioliti LH, Silva CL. Downmodulation of CD18 and CD86 on macrophages and VLA-4 on lymphocytes in experimental tuberculosis. Scand J Immunol (2001) 54:564-73. doi:10.1046/j.1365-3083.2001.00996.x
-
(2001)
Scand J Immunol
, vol.54
, pp. 564-573
-
-
Bonato, V.L.1
Medeiros, A.I.2
Lima, V.M.3
Dias, A.R.4
Faccioliti, L.H.5
Silva, C.L.6
-
62
-
-
0344562930
-
Suppression of T and B lymphocyte activation by a Yersinia pseudotuberculosis virulence factor, yopH
-
Yao T, Mecsas J, Healy JI, Falkow S, Chien Y. Suppression of T and B lymphocyte activation by a Yersinia pseudotuberculosis virulence factor, yopH. J Exp Med (1999) 190:1343-50. doi:10.1084/jem.190.9.1343
-
(1999)
J Exp Med
, vol.190
, pp. 1343-1350
-
-
Yao, T.1
Mecsas, J.2
Healy, J.I.3
Falkow, S.4
Chien, Y.5
-
63
-
-
25444510358
-
The Nef protein of HIV-1 induces loss of cell surface costimulatory molecules CD80 and CD86 in APCs
-
Chaudhry A, Das SR, Hussain A, Mayor S, George A, Bal V, et al. The Nef protein of HIV-1 induces loss of cell surface costimulatory molecules CD80 and CD86 in APCs. J Immunol (2005) 175:4566-74. doi:10.4049/jimmunol.175.7.4566
-
(2005)
J Immunol
, vol.175
, pp. 4566-4574
-
-
Chaudhry, A.1
Das, S.R.2
Hussain, A.3
Mayor, S.4
George, A.5
Bal, V.6
-
64
-
-
20844458651
-
Antagonism between MyD88-and TRIF-dependent signals in B7RP-1 up-regulation
-
Zhou Z, Hoebe K, Du X, Jiang Z, Shamel L, Beutler B. Antagonism between MyD88-and TRIF-dependent signals in B7RP-1 up-regulation. Eur J Immunol (2005) 35:1918-27. doi:10.1002/eji.200525971
-
(2005)
Eur J Immunol
, vol.35
, pp. 1918-1927
-
-
Zhou, Z.1
Hoebe, K.2
Du, X.3
Jiang, Z.4
Shamel, L.5
Beutler, B.6
-
65
-
-
0042195831
-
Costimulation through the inducible costimulator ligand is essential for both T helper and B cell functions in T cell-dependent B cell responses
-
Mak TW, Shahinian A, Yoshinaga SK, Wakeham A, Boucher L-M, Pintilie M, et al. Costimulation through the inducible costimulator ligand is essential for both T helper and B cell functions in T cell-dependent B cell responses. Nat Immunol (2003) 4:765-72. doi:10.1038/ni947
-
(2003)
Nat Immunol
, vol.4
, pp. 765-772
-
-
Mak, T.W.1
Shahinian, A.2
Yoshinaga, S.K.3
Wakeham, A.4
Boucher, L.-M.5
Pintilie, M.6
-
66
-
-
0042738928
-
Impaired germinal center formation and recall T-cell-dependent immune responses in mice lacking the costimulatory ligand B7-H2
-
Wong S-C, Oh E, Ng C-H, Lam K-P. Impaired germinal center formation and recall T-cell-dependent immune responses in mice lacking the costimulatory ligand B7-H2. Blood (2003) 102:1381-8. doi:10.1182/blood-2002-08-2416
-
(2003)
Blood
, vol.102
, pp. 1381-1388
-
-
Wong, S.-C.1
Oh, E.2
Ng, C.-H.3
Lam, K.-P.4
-
67
-
-
7244257496
-
Effect of inducible costimulator blockade on the pathological and protective immune responses induced by the gastrointestinal helminth Trichinella spiralis
-
Scales HE, Ierna MX, Gutierrez-Ramos J-C, Coyle AJ, Garside P, Lawrence CE. Effect of inducible costimulator blockade on the pathological and protective immune responses induced by the gastrointestinal helminth Trichinella spiralis. Eur J Immunol (2004) 34:2854-62. doi:10.1002/eji.200324364
-
(2004)
Eur J Immunol
, vol.34
, pp. 2854-2862
-
-
Scales, H.E.1
Ierna, M.X.2
Gutierrez-Ramos, J.-C.3
Coyle, A.J.4
Garside, P.5
Lawrence, C.E.6
-
68
-
-
12444300786
-
Involvement of ICOS-B7RP-1 costimulatory pathway in the regulation of immune responses to Leishmania major and Nippostrongylus brasiliensis infections
-
Miyahira Y, Akiba H, Ogawa S-H, Ishi T, Watanabe S, Kobayashi S, et al. Involvement of ICOS-B7RP-1 costimulatory pathway in the regulation of immune responses to Leishmania major and Nippostrongylus brasiliensis infections. Immunol Lett (2003) 89:193-9. doi:10.1016/S0165-2478(03)00137-8
-
(2003)
Immunol Lett
, vol.89
, pp. 193-199
-
-
Miyahira, Y.1
Akiba, H.2
Ogawa, S.-H.3
Ishi, T.4
Watanabe, S.5
Kobayashi, S.6
-
69
-
-
22244481598
-
Inducible costimulator is required for type 2 antibody isotype switching but not T helper cell type 2 responses in chronic nematode infection
-
Loke P, Zang X, Hsuan L, Waitz R, Locksley RM, Allen JE, et al. Inducible costimulator is required for type 2 antibody isotype switching but not T helper cell type 2 responses in chronic nematode infection. Proc Natl Acad Sci U S A (2005) 102:9872-7. doi:10.1073/pnas.0503961102
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 9872-9877
-
-
Loke, P.1
Zang, X.2
Hsuan, L.3
Waitz, R.4
Locksley, R.M.5
Allen, J.E.6
-
71
-
-
23444434705
-
The role of ICOS in the CXCR5+ follicular B helper T cell maintenance in vivo
-
Akiba H, Takeda K, Kojima Y, Usui Y, Harada N, Yamazaki T, et al. The role of ICOS in the CXCR5+ follicular B helper T cell maintenance in vivo. J Immunol (2005) 175:2340-8. doi:10.4049/jimmunol.175.4.2340
-
(2005)
J Immunol
, vol.175
, pp. 2340-2348
-
-
Akiba, H.1
Takeda, K.2
Kojima, Y.3
Usui, Y.4
Harada, N.5
Yamazaki, T.6
-
72
-
-
0035869525
-
Cutting edge: critical role of inducible costimulator in germinal center reactions
-
Dong C, Temann UA, Flavell RA. Cutting edge: critical role of inducible costimulator in germinal center reactions. J Immunol (2001) 166:3659-62. doi:10.4049/jimmunol.166.6.3659
-
(2001)
J Immunol
, vol.166
, pp. 3659-3662
-
-
Dong, C.1
Temann, U.A.2
Flavell, R.A.3
-
73
-
-
58849137120
-
A novel ICOS-independent, but CD28-and SAP-dependent, pathway of T cell-dependent, polysaccharide-specific humoral immunity in response to intact Streptococcus pneumoniae versus pneumococcal conjugate vaccine
-
Chen Q, Cannons JL, Paton JC, Akiba H, Schwartzberg PL, Snapper CM. A novel ICOS-independent, but CD28-and SAP-dependent, pathway of T cell-dependent, polysaccharide-specific humoral immunity in response to intact Streptococcus pneumoniae versus pneumococcal conjugate vaccine. J Immunol (2008) 181:8258-66. doi:10.4049/jimmunol.181.12.8258
-
(2008)
J Immunol
, vol.181
, pp. 8258-8266
-
-
Chen, Q.1
Cannons, J.L.2
Paton, J.C.3
Akiba, H.4
Schwartzberg, P.L.5
Snapper, C.M.6
-
74
-
-
0037017391
-
Low-level hypermutation in T cell-independent germinal centers compared with high mutation rates associated with T cell-dependent germinal centers
-
Toellner K-M, Jenkinson WE, Taylor DR, Khan M, Sze DM-Y, Sansom DM, et al. Low-level hypermutation in T cell-independent germinal centers compared with high mutation rates associated with T cell-dependent germinal centers. J Exp Med (2002) 195:383-9. doi:10.1084/jem.20011112
-
(2002)
J Exp Med
, vol.195
, pp. 383-389
-
-
Toellner, K.-M.1
Jenkinson, W.E.2
Taylor, D.R.3
Khan, M.4
Sze, D.M.-Y.5
Sansom, D.M.6
-
75
-
-
0034614899
-
Germinal centers without T cells
-
de Vinuesa CG, Cook MC, Ball J, Drew M, Sunners Y, Cascalho M, et al. Germinal centers without T cells. J Exp Med (2000) 191:485-94. doi:10.1084/jem.191.3.485
-
(2000)
J Exp Med
, vol.191
, pp. 485-494
-
-
de Vinuesa, C.G.1
Cook, M.C.2
Ball, J.3
Drew, M.4
Sunners, Y.5
Cascalho, M.6
-
76
-
-
0035804268
-
ICOS is critical for CD40-mediated antibody class switching
-
McAdam AJ, Greenwald RJ, Levin MA, Chernova T, Malenkovich N, Ling V, et al. ICOS is critical for CD40-mediated antibody class switching. Nature (2001) 409:102-5. doi:10.1038/35051107
-
(2001)
Nature
, vol.409
, pp. 102-105
-
-
McAdam, A.J.1
Greenwald, R.J.2
Levin, M.A.3
Chernova, T.4
Malenkovich, N.5
Ling, V.6
-
77
-
-
77958487137
-
Plasticity and heterogeneity in the generation of memory B cells and long-lived plasma cells: the influence of germinal center interactions and dynamics
-
Good-Jacobson KL, Shlomchik MJ. Plasticity and heterogeneity in the generation of memory B cells and long-lived plasma cells: the influence of germinal center interactions and dynamics. J Immunol (2010) 185:3117-25. doi:10.4049/jimmunol.1001155
-
(2010)
J Immunol
, vol.185
, pp. 3117-3125
-
-
Good-Jacobson, K.L.1
Shlomchik, M.J.2
-
78
-
-
63149093151
-
B7RP-1 blockade ameliorates autoimmunity through regulation of follicular helper T cells
-
Hu Y-L, Metz DP, Chung J, Siu G, Zhang M. B7RP-1 blockade ameliorates autoimmunity through regulation of follicular helper T cells. J Immunol (2009) 182:1421-8. doi:10.4049/jimmunol.182.3.1421
-
(2009)
J Immunol
, vol.182
, pp. 1421-1428
-
-
Hu, Y.-L.1
Metz, D.P.2
Chung, J.3
Siu, G.4
Zhang, M.5
-
79
-
-
79959328032
-
ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6
-
Choi YS, Kageyama R, Eto D, Escobar TC, Johnston RJ, Monticelli L, et al. ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6. Immunity (2011) 34:932-46. doi:10.1016/j.immuni.2011.03.023
-
(2011)
Immunity
, vol.34
, pp. 932-946
-
-
Choi, Y.S.1
Kageyama, R.2
Eto, D.3
Escobar, T.C.4
Johnston, R.J.5
Monticelli, L.6
-
80
-
-
84922695639
-
ICOS maintains the T follicular helper cell phenotype by down-regulating Krüppel-like factor 2
-
Weber JP, Fuhrmann F, Feist RK, Lahmann A, Al Baz MS, Gentz L-J, et al. ICOS maintains the T follicular helper cell phenotype by down-regulating Krüppel-like factor 2. J Exp Med (2015) 212:217-33. doi:10.1084/jem.20141432
-
(2015)
J Exp Med
, vol.212
, pp. 217-233
-
-
Weber, J.P.1
Fuhrmann, F.2
Feist, R.K.3
Lahmann, A.4
Al Baz, M.S.5
Gentz, L.-J.6
-
81
-
-
84923044855
-
ICOS coreceptor signaling inactivates the transcription factor FOXO1 to promote Tfh cell differentiation
-
Stone EL, Pepper M, Katayama CD, Kerdiles YM, Lai C-Y, Emslie E, et al. ICOS coreceptor signaling inactivates the transcription factor FOXO1 to promote Tfh cell differentiation. Immunity (2015) 42:239-51. doi:10.1016/j.immuni.2015.01.017
-
(2015)
Immunity
, vol.42
, pp. 239-251
-
-
Stone, E.L.1
Pepper, M.2
Katayama, C.D.3
Kerdiles, Y.M.4
Lai, C.-Y.5
Emslie, E.6
-
82
-
-
69249109601
-
Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation
-
Johnston RJ, Poholek AC, DiToro D, Yusuf I, Eto D, Barnett B, et al. Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation. Science (2009) 325:1006-10. doi:10.1126/science.1175870
-
(2009)
Science
, vol.325
, pp. 1006-1010
-
-
Johnston, R.J.1
Poholek, A.C.2
DiToro, D.3
Yusuf, I.4
Eto, D.5
Barnett, B.6
-
83
-
-
69249101229
-
Bcl6 mediates the development of T follicular helper cells
-
Nurieva RI, Chung Y, Martinez GJ, Yang XO, Tanaka S, Matskevitch TD, et al. Bcl6 mediates the development of T follicular helper cells. Science (2009) 325:1001-5. doi:10.1126/science.1176676
-
(2009)
Science
, vol.325
, pp. 1001-1005
-
-
Nurieva, R.I.1
Chung, Y.2
Martinez, G.J.3
Yang, X.O.4
Tanaka, S.5
Matskevitch, T.D.6
-
84
-
-
84908148200
-
T Follicular helper cell differentiation, function, and roles in disease
-
Crotty S. T Follicular helper cell differentiation, function, and roles in disease. Immunity (2014) 41:529-42. doi:10.1016/j.immuni.2014.10.004
-
(2014)
Immunity
, vol.41
, pp. 529-542
-
-
Crotty, S.1
-
85
-
-
84933678575
-
CD8a(-) dendritic cells induce antigen-specific T follicular helper cells generating efficient humoral immune responses
-
Shin C, Han J-A, Koh H, Choi B, Cho Y, Jeong H, et al. CD8a(-) dendritic cells induce antigen-specific T follicular helper cells generating efficient humoral immune responses. Cell Rep (2015) 11:1929-40. doi:10.1016/j.celrep.2015.05.042
-
(2015)
Cell Rep
, vol.11
, pp. 1929-1940
-
-
Shin, C.1
Han, J.-A.2
Koh, H.3
Choi, B.4
Cho, Y.5
Jeong, H.6
-
86
-
-
84923778281
-
T-B-cell entanglement and ICOSL-driven feed-forward regulation of germinal centre reaction
-
Liu D, Xu H, Shih C, Wan Z, Ma X, Ma W, et al. T-B-cell entanglement and ICOSL-driven feed-forward regulation of germinal centre reaction. Nature (2015) 517:214-8. doi:10.1038/nature13803
-
(2015)
Nature
, vol.517
, pp. 214-218
-
-
Liu, D.1
Xu, H.2
Shih, C.3
Wan, Z.4
Ma, X.5
Ma, W.6
-
87
-
-
80051618656
-
Cutting edge: dendritic cell-restricted antigen presentation initiates the follicular helper T cell program but cannot complete ultimate effector differentiation
-
Goenka R, Barnett LG, Silver JS, O'Neill PJ, Hunter CA, Cancro MP, et al. Cutting edge: dendritic cell-restricted antigen presentation initiates the follicular helper T cell program but cannot complete ultimate effector differentiation. J Immunol (2011) 187:1091-5. doi:10.4049/jimmunol.1100853
-
(2011)
J Immunol
, vol.187
, pp. 1091-1095
-
-
Goenka, R.1
Barnett, L.G.2
Silver, J.S.3
O'Neill, P.J.4
Hunter, C.A.5
Cancro, M.P.6
-
88
-
-
46749115446
-
A fundamental role for interleukin-21 in the generation of T follicular helper cells
-
Vogelzang A, McGuire HM, Yu D, Sprent J, Mackay CR, King C. A fundamental role for interleukin-21 in the generation of T follicular helper cells. Immunity (2008) 29:127-37. doi:10.1016/j.immuni.2008.06.001
-
(2008)
Immunity
, vol.29
, pp. 127-137
-
-
Vogelzang, A.1
McGuire, H.M.2
Yu, D.3
Sprent, J.4
Mackay, C.R.5
King, C.6
-
89
-
-
84875414166
-
Young lives lost as B cells falter: what we are learning about antibody responses in malaria
-
Portugal S, Pierce SK, Crompton PD. Young lives lost as B cells falter: what we are learning about antibody responses in malaria. J Immunol (2013) 190:3039-46. doi:10.4049/jimmunol.1203067
-
(2013)
J Immunol
, vol.190
, pp. 3039-3046
-
-
Portugal, S.1
Pierce, S.K.2
Crompton, P.D.3
-
90
-
-
84897501021
-
B cells in T follicular helper cell development and function: separable roles in delivery of ICOS ligand and antigen
-
Weinstein JS, Bertino SA, Hernandez SG, Poholek AC, Teplitzky TB, Nowyhed HN, et al. B cells in T follicular helper cell development and function: separable roles in delivery of ICOS ligand and antigen. J Immunol (2014) 192:3166-79. doi:10.4049/jimmunol.1302617
-
(2014)
J Immunol
, vol.192
, pp. 3166-3179
-
-
Weinstein, J.S.1
Bertino, S.A.2
Hernandez, S.G.3
Poholek, A.C.4
Teplitzky, T.B.5
Nowyhed, H.N.6
-
91
-
-
77955924180
-
Follicular helper T cell differentiation requires continuous antigen presentation that is independent of unique B cell signaling
-
Deenick EK, Chan A, Ma CS, Gatto D, Schwartzberg PL, Brink R, et al. Follicular helper T cell differentiation requires continuous antigen presentation that is independent of unique B cell signaling. Immunity (2010) 33:241-53. doi:10.1016/j.immuni.2010.07.015
-
(2010)
Immunity
, vol.33
, pp. 241-253
-
-
Deenick, E.K.1
Chan, A.2
Ma, C.S.3
Gatto, D.4
Schwartzberg, P.L.5
Brink, R.6
-
92
-
-
84876793426
-
Follicular T-helper cell recruitment governed by bystander B cells and ICOS-driven motility
-
Xu H, Li X, Liu D, Li J, Zhang X, Chen X, et al. Follicular T-helper cell recruitment governed by bystander B cells and ICOS-driven motility. Nature (2013) 496:523-7. doi:10.1038/nature12058
-
(2013)
Nature
, vol.496
, pp. 523-527
-
-
Xu, H.1
Li, X.2
Liu, D.3
Li, J.4
Zhang, X.5
Chen, X.6
-
93
-
-
84948441210
-
Osteopontin in immune-mediated diseases
-
Rittling SR, Singh R. Osteopontin in immune-mediated diseases. J Dent Res (2015) 94:1638-45. doi:10.1177/0022034515605270
-
(2015)
J Dent Res
, vol.94
, pp. 1638-1645
-
-
Rittling, S.R.1
Singh, R.2
-
94
-
-
0038393016
-
IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway
-
Fitzgerald KA, McWhirter SM, Faia KL, Rowe DC, Latz E, Golenbock DT, et al. IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway. Nat Immunol (2003) 4:491-6. doi:10.1038/ni921
-
(2003)
Nat Immunol
, vol.4
, pp. 491-496
-
-
Fitzgerald, K.A.1
McWhirter, S.M.2
Faia, K.L.3
Rowe, D.C.4
Latz, E.5
Golenbock, D.T.6
-
95
-
-
0038363463
-
Triggering the interferon antiviral response through an IKK-related pathway
-
Sharma S, Tenoever BR, Grandvaux N, Zhou G-P, Lin R, Hiscott J. Triggering the interferon antiviral response through an IKK-related pathway. Science (2003) 300:1148-51. doi:10.1126/science.1081315
-
(2003)
Science
, vol.300
, pp. 1148-1151
-
-
Sharma, S.1
Tenoever, B.R.2
Grandvaux, N.3
Zhou, G.-P.4
Lin, R.5
Hiscott, J.6
-
96
-
-
84866353412
-
FOXO transcription factors throughout T cell biology
-
Hedrick SM, Hess Michelini R, Doedens AL, Goldrath AW, Stone EL. FOXO transcription factors throughout T cell biology. Nat Rev Immunol (2012) 12:649-61. doi:10.1038/nri3278
-
(2012)
Nat Rev Immunol
, vol.12
, pp. 649-661
-
-
Hedrick, S.M.1
Hess Michelini, R.2
Doedens, A.L.3
Goldrath, A.W.4
Stone, E.L.5
-
97
-
-
84860363209
-
A germinal center-independent pathway generates unswitched memory B cells early in the primary response
-
Taylor JJ, Pape KA, Jenkins MK. A germinal center-independent pathway generates unswitched memory B cells early in the primary response. J Exp Med (2012) 209:597-606. doi:10.1084/jem.20111696
-
(2012)
J Exp Med
, vol.209
, pp. 597-606
-
-
Taylor, J.J.1
Pape, K.A.2
Jenkins, M.K.3
-
98
-
-
23844445862
-
Two waves of memory B-cell generation in the primary immune response
-
Inamine A, Takahashi Y, Baba N, Miyake K, Tokuhisa T, Takemori T, et al. Two waves of memory B-cell generation in the primary immune response. Int Immunol (2005) 17:581-9. doi:10.1093/intimm/dxh241
-
(2005)
Int Immunol
, vol.17
, pp. 581-589
-
-
Inamine, A.1
Takahashi, Y.2
Baba, N.3
Miyake, K.4
Tokuhisa, T.5
Takemori, T.6
-
99
-
-
84958831765
-
A temporal switch in the germinal center determines differential output of memory B and plasma cells
-
Weisel FJ, Zuccarino-Catania GV, Chikina M, Shlomchik MJ. A temporal switch in the germinal center determines differential output of memory B and plasma cells. Immunity (2016) 44:116-30. doi:10.1016/j.immuni.2015.12.004
-
(2016)
Immunity
, vol.44
, pp. 116-130
-
-
Weisel, F.J.1
Zuccarino-Catania, G.V.2
Chikina, M.3
Shlomchik, M.J.4
-
100
-
-
5644273872
-
Involvement of inducible costimulator in the exaggerated memory B cell and plasma cell generation in systemic lupus erythematosus
-
Hutloff A, Büchner K, Reiter K, Baelde HJ, Odendahl M, Jacobi A, et al. Involvement of inducible costimulator in the exaggerated memory B cell and plasma cell generation in systemic lupus erythematosus. Arthritis Rheum (2004) 50:3211-20. doi:10.1002/art.20519
-
(2004)
Arthritis Rheum
, vol.50
, pp. 3211-3220
-
-
Hutloff, A.1
Büchner, K.2
Reiter, K.3
Baelde, H.J.4
Odendahl, M.5
Jacobi, A.6
-
101
-
-
34250883267
-
Human IgM+CD27+ B cells: memory B cells or "memory" B cells?
-
Tangye SG, Good KL. Human IgM+CD27+ B cells: memory B cells or "memory" B cells? J Immunol (2007) 179:13-9. doi:10.4049/jimmunol.179.1.13
-
(2007)
J Immunol
, vol.179
, pp. 13-19
-
-
Tangye, S.G.1
Good, K.L.2
-
102
-
-
34447570588
-
The role of ICOS in the development of CD4 T cell help and the reactivation of memory T cells
-
Mahajan S, Cervera A, MacLeod M, Fillatreau S, Perona-Wright G, Meek S, et al. The role of ICOS in the development of CD4 T cell help and the reactivation of memory T cells. Eur J Immunol (2007) 37:1796-808. doi:10.1002/eji.200636661
-
(2007)
Eur J Immunol
, vol.37
, pp. 1796-1808
-
-
Mahajan, S.1
Cervera, A.2
MacLeod, M.3
Fillatreau, S.4
Perona-Wright, G.5
Meek, S.6
-
103
-
-
0036918725
-
Role of ICOS versus CD28 in antiviral immunity
-
Bertram EM, Tafuri A, Shahinian A, Chan VSF, Hunziker L, Recher M, et al. Role of ICOS versus CD28 in antiviral immunity. Eur J Immunol (2002) 32:3376-85. doi:10.1002/1521-4141(200212)32:12<3376::AID-IMMU3376>3.0.CO;2-Y
-
(2002)
Eur J Immunol
, vol.32
, pp. 3376-3385
-
-
Bertram, E.M.1
Tafuri, A.2
Shahinian, A.3
Chan, V.S.F.4
Hunziker, L.5
Recher, M.6
-
104
-
-
42149168527
-
ICOS, CD40, and lymphotoxin beta receptors signal sequentially and interdependently to initiate a germinal center reaction
-
Vu F, Dianzani U, Ware CF, Mak T, Gommerman JL. ICOS, CD40, and lymphotoxin beta receptors signal sequentially and interdependently to initiate a germinal center reaction. J Immunol (2008) 180:2284-93. doi:10.4049/jimmunol.180.4.2284
-
(2008)
J Immunol
, vol.180
, pp. 2284-2293
-
-
Vu, F.1
Dianzani, U.2
Ware, C.F.3
Mak, T.4
Gommerman, J.L.5
-
105
-
-
84873748148
-
Lymphotoxin α1β2 expression on B cells is required for follicular dendritic cell activation during the germinal center response
-
Myers RC, King RG, Carter RH, Justement LB. Lymphotoxin α1β2 expression on B cells is required for follicular dendritic cell activation during the germinal center response. Eur J Immunol (2013) 43:348-59. doi:10.1002/eji.201242471
-
(2013)
Eur J Immunol
, vol.43
, pp. 348-359
-
-
Myers, R.C.1
King, R.G.2
Carter, R.H.3
Justement, L.B.4
-
106
-
-
84930417028
-
ICOS is required for the generation of both central and effector CD4(+) memory T-cell populations following acute bacterial infection
-
Marriott CL, Carlesso G, Herbst R, Withers DR. ICOS is required for the generation of both central and effector CD4(+) memory T-cell populations following acute bacterial infection. Eur J Immunol (2015) 45:1706-15. doi:10.1002/eji.201445421
-
(2015)
Eur J Immunol
, vol.45
, pp. 1706-1715
-
-
Marriott, C.L.1
Carlesso, G.2
Herbst, R.3
Withers, D.R.4
-
107
-
-
74049131014
-
Different routes of bacterial infection induce long-lived TH1 memory cells and short-lived TH17 cells
-
Pepper M, Linehan JL, Pagán AJ, Zell T, Dileepan T, Cleary PP, et al. Different routes of bacterial infection induce long-lived TH1 memory cells and short-lived TH17 cells. Nat Immunol (2010) 11:83-9. doi:10.1038/ni.1826
-
(2010)
Nat Immunol
, vol.11
, pp. 83-89
-
-
Pepper, M.1
Linehan, J.L.2
Pagán, A.J.3
Zell, T.4
Dileepan, T.5
Cleary, P.P.6
-
108
-
-
84934889059
-
ICOS and Bcl6-dependent pathways maintain a CD4 T cell population with memory-like properties during tuberculosis
-
Moguche AO, Shafiani S, Clemons C, Larson RP, Dinh C, Higdon LE, et al. ICOS and Bcl6-dependent pathways maintain a CD4 T cell population with memory-like properties during tuberculosis. J Exp Med (2015) 212:715-28. doi:10.1084/jem.20141518
-
(2015)
J Exp Med
, vol.212
, pp. 715-728
-
-
Moguche, A.O.1
Shafiani, S.2
Clemons, C.3
Larson, R.P.4
Dinh, C.5
Higdon, L.E.6
-
109
-
-
80755172184
-
Opposing signals from the Bcl6 transcription factor and the interleukin-2 receptor generate T helper 1 central and effector memory cells
-
Pepper M, Pagán AJ, Igyártó BZ, Taylor JJ, Jenkins MK. Opposing signals from the Bcl6 transcription factor and the interleukin-2 receptor generate T helper 1 central and effector memory cells. Immunity (2011) 35:583-95. doi:10.1016/j.immuni.2011.09.009
-
(2011)
Immunity
, vol.35
, pp. 583-595
-
-
Pepper, M.1
Pagán, A.J.2
Igyártó, B.Z.3
Taylor, J.J.4
Jenkins, M.K.5
-
110
-
-
66949171812
-
Impaired CD4 and CD8 effector function and decreased memory T cell populations in ICOS-deficient patients
-
Takahashi N, Matsumoto K, Saito H, Nanki T, Miyasaka N, Kobata T, et al. Impaired CD4 and CD8 effector function and decreased memory T cell populations in ICOS-deficient patients. J Immunol (2009) 182:5515-27. doi:10.4049/jimmunol.0803256
-
(2009)
J Immunol
, vol.182
, pp. 5515-5527
-
-
Takahashi, N.1
Matsumoto, K.2
Saito, H.3
Nanki, T.4
Miyasaka, N.5
Kobata, T.6
-
111
-
-
0037340349
-
Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency
-
Grimbacher B, Hutloff A, Schlesier M, Glocker E, Warnatz K, Dräger R, et al. Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency. Nat Immunol (2003) 4:261-8. doi:10.1038/ni902
-
(2003)
Nat Immunol
, vol.4
, pp. 261-268
-
-
Grimbacher, B.1
Hutloff, A.2
Schlesier, M.3
Glocker, E.4
Warnatz, K.5
Dräger, R.6
-
112
-
-
2342467376
-
Common variable immunodeficiency: a review
-
Di Renzo M, Pasqui AL, Auteri A. Common variable immunodeficiency: a review. Clin Exp Med (2004) 3:211-7. doi:10.1007/s10238-004-0027-2
-
(2004)
Clin Exp Med
, vol.3
, pp. 211-217
-
-
Di Renzo, M.1
Pasqui, A.L.2
Auteri, A.3
-
113
-
-
33749151018
-
ICOS deficiency is associated with a severe reduction of CXCR5+CD4 germinal center Th cells
-
Bossaller L, Burger J, Draeger R, Grimbacher B, Knoth R, Plebani A, et al. ICOS deficiency is associated with a severe reduction of CXCR5+CD4 germinal center Th cells. J Immunol (2006) 177:4927-32. doi:10.4049/jimmunol.177.7.4927
-
(2006)
J Immunol
, vol.177
, pp. 4927-4932
-
-
Bossaller, L.1
Burger, J.2
Draeger, R.3
Grimbacher, B.4
Knoth, R.5
Plebani, A.6
-
114
-
-
84885741984
-
Circulating precursor CCR7(lo)PD-1(hi) CXCR5+ CD4+ T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure
-
He J, Tsai LM, Leong YA, Hu X, Ma CS, Chevalier N, et al. Circulating precursor CCR7(lo)PD-1(hi) CXCR5+ CD4+ T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure. Immunity (2013) 39:770-81. doi:10.1016/j.immuni.2013.09.007
-
(2013)
Immunity
, vol.39
, pp. 770-781
-
-
He, J.1
Tsai, L.M.2
Leong, Y.A.3
Hu, X.4
Ma, C.S.5
Chevalier, N.6
-
115
-
-
84885743368
-
Human circulating PD-1(+)CXCR3(-)CXCR5(+) memory Tfh Cells are highly functional and correlate with broadly neutralizing HIV antibody responses
-
Locci M, Havenar-Daughton C, Landais E, Wu J, Kroenke MA, Arlehamn CL, et al. Human circulating PD-1(+)CXCR3(-)CXCR5(+) memory Tfh Cells are highly functional and correlate with broadly neutralizing HIV antibody responses. Immunity (2013) 39:758-69. doi:10.1016/j.immuni.2013.08.031
-
(2013)
Immunity
, vol.39
, pp. 758-769
-
-
Locci, M.1
Havenar-Daughton, C.2
Landais, E.3
Wu, J.4
Kroenke, M.A.5
Arlehamn, C.L.6
-
116
-
-
74849138095
-
Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus
-
Simpson N, Gatenby PA, Wilson A, Malik S, Fulcher DA, Tangye SG, et al. Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus. Arthritis Rheum (2010) 62:234-44. doi:10.1002/art.25032
-
(2010)
Arthritis Rheum
, vol.62
, pp. 234-244
-
-
Simpson, N.1
Gatenby, P.A.2
Wilson, A.3
Malik, S.4
Fulcher, D.A.5
Tangye, S.G.6
-
117
-
-
84930040863
-
Genetics and pathogenesis of systemic lupus erythematosus and lupus nephritis
-
Mohan C, Putterman C. Genetics and pathogenesis of systemic lupus erythematosus and lupus nephritis. Nat Rev Nephrol (2015) 11:329-41. doi:10.1038/nrneph.2015.33
-
(2015)
Nat Rev Nephrol
, vol.11
, pp. 329-341
-
-
Mohan, C.1
Putterman, C.2
-
118
-
-
34247551065
-
Expression and function of inducible co-stimulator in patients with systemic lupus erythematosus: possible involvement in excessive interferon-gamma and anti-double-stranded DNA antibody production
-
Kawamoto M, Harigai M, Hara M, Kawaguchi Y, Tezuka K, Tanaka M, et al. Expression and function of inducible co-stimulator in patients with systemic lupus erythematosus: possible involvement in excessive interferon-gamma and anti-double-stranded DNA antibody production. Arthritis Res Ther (2006) 8:R62. doi:10.1186/ar1928
-
(2006)
Arthritis Res Ther
, vol.8
-
-
Kawamoto, M.1
Harigai, M.2
Hara, M.3
Kawaguchi, Y.4
Tezuka, K.5
Tanaka, M.6
-
119
-
-
60849107595
-
A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice
-
Bubier JA, Sproule TJ, Foreman O, Spolski R, Shaffer DJ, Morse HC, et al. A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice. Proc Natl Acad Sci U S A (2009) 106:1518-23. doi:10.1073/pnas.0807309106
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 1518-1523
-
-
Bubier, J.A.1
Sproule, T.J.2
Foreman, O.3
Spolski, R.4
Shaffer, D.J.5
Morse, H.C.6
-
120
-
-
84924993521
-
Local triggering of the ICOS coreceptor by CD11c(+) myeloid cells drives organ inflammation in lupus
-
Teichmann LL, Cullen JL, Kashgarian M, Dong C, Craft J, Shlomchik MJ. Local triggering of the ICOS coreceptor by CD11c(+) myeloid cells drives organ inflammation in lupus. Immunity (2015) 42:552-65. doi:10.1016/j.immuni.2015.02.015
-
(2015)
Immunity
, vol.42
, pp. 552-565
-
-
Teichmann, L.L.1
Cullen, J.L.2
Kashgarian, M.3
Dong, C.4
Craft, J.5
Shlomchik, M.J.6
-
121
-
-
21144438325
-
A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity
-
Vinuesa CG, Cook MC, Angelucci C, Athanasopoulos V, Rui L, Hill KM, et al. A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity. Nature (2005) 435:452-8. doi:10.1038/nature03555
-
(2005)
Nature
, vol.435
, pp. 452-458
-
-
Vinuesa, C.G.1
Cook, M.C.2
Angelucci, C.3
Athanasopoulos, V.4
Rui, L.5
Hill, K.M.6
-
122
-
-
36048946330
-
Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA
-
Yu D, Tan AH-M, Hu X, Athanasopoulos V, Simpson N, Silva DG, et al. Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA. Nature (2007) 450:299-303. doi:10.1038/nature06253
-
(2007)
Nature
, vol.450
, pp. 299-303
-
-
Yu, D.1
Tan, A.H.-M.2
Hu, X.3
Athanasopoulos, V.4
Simpson, N.5
Silva, D.G.6
-
123
-
-
77954959530
-
Roquin binds inducible costimulator mRNA and effectors of mRNA decay to induce microRNA-independent post-transcriptional repression
-
Glasmacher E, Hoefig KP, Vogel KU, Rath N, Du L, Wolf C, et al. Roquin binds inducible costimulator mRNA and effectors of mRNA decay to induce microRNA-independent post-transcriptional repression. Nat Immunol (2010) 11:725-33. doi:10.1038/ni.1902
-
(2010)
Nat Immunol
, vol.11
, pp. 725-733
-
-
Glasmacher, E.1
Hoefig, K.P.2
Vogel, K.U.3
Rath, N.4
Du, L.5
Wolf, C.6
-
124
-
-
85027542056
-
Administration of AMG 557, a human Anti-B7RP-1 (ICOSL) antibody, leads to the selective inhibition of Anti-KLH IgG responses in subjects with SLE: results of a phase 1 randomized, double-blind, placebo-controlled, sequential, rising, multiple-dose study [abstract]
-
Sullivan B, Tsuji WH, Chindalore VL, Geppert TD, Rudinskaya A, Pardo P, et al. Administration of AMG 557, a human Anti-B7RP-1 (ICOSL) antibody, leads to the selective inhibition of Anti-KLH IgG responses in subjects with SLE: results of a phase 1 randomized, double-blind, placebo-controlled, sequential, rising, multiple-dose study [abstract]. Arthritis Rheum (2013) 65:1743
-
(2013)
Arthritis Rheum
, vol.65
, pp. 1743
-
-
Sullivan, B.1
Tsuji, W.H.2
Chindalore, V.L.3
Geppert, T.D.4
Rudinskaya, A.5
Pardo, P.6
-
125
-
-
84989302826
-
Inducible T-cell co-stimulator ligand (ICOSL) blockade leads to selective inhibition of anti-KLH IgG responses in subjects with systemic lupus erythematosus
-
Sullivan BA, Tsuji W, Kivitz A, Peng J, Arnold GE, Boedigheimer MJ, et al. Inducible T-cell co-stimulator ligand (ICOSL) blockade leads to selective inhibition of anti-KLH IgG responses in subjects with systemic lupus erythematosus. Lupus Sci Med (2016) 3:e000146. doi:10.1136/lupus-2016-000146
-
(2016)
Lupus Sci Med
, vol.3
-
-
Sullivan, B.A.1
Tsuji, W.2
Kivitz, A.3
Peng, J.4
Arnold, G.E.5
Boedigheimer, M.J.6
-
127
-
-
84925121085
-
ICOS:ICOS-ligand interaction is required for type 2 innate lymphoid cell function, homeostasis, and induction of airway hyperreactivity
-
Maazi H, Patel N, Sankaranarayanan I, Suzuki Y, Rigas D, Soroosh P, et al. ICOS:ICOS-ligand interaction is required for type 2 innate lymphoid cell function, homeostasis, and induction of airway hyperreactivity. Immunity (2015) 42:538-51. doi:10.1016/j.immuni.2015.02.007
-
(2015)
Immunity
, vol.42
, pp. 538-551
-
-
Maazi, H.1
Patel, N.2
Sankaranarayanan, I.3
Suzuki, Y.4
Rigas, D.5
Soroosh, P.6
-
128
-
-
23044471742
-
Inhibition of chronic rejection and development of tolerogenic T cells after ICOS-ICOSL and CD40-CD40L co-stimulation blockade
-
Guillonneau C, Aubry V, Renaudin K, Séveno C, Usal C, Tezuka K, et al. Inhibition of chronic rejection and development of tolerogenic T cells after ICOS-ICOSL and CD40-CD40L co-stimulation blockade. Transplantation (2005) 80:546-54. doi:10.1097/01.TP.0000165429.57421.D6
-
(2005)
Transplantation
, vol.80
, pp. 546-554
-
-
Guillonneau, C.1
Aubry, V.2
Renaudin, K.3
Séveno, C.4
Usal, C.5
Tezuka, K.6
-
129
-
-
50649125413
-
Further study of anti-ICOS immunotherapy for rat cardiac allograft rejection
-
Pan X-C, Guo L, Deng Y-B, Naruse K, Kimura H, Sugawara Y, et al. Further study of anti-ICOS immunotherapy for rat cardiac allograft rejection. Surg Today (2008) 38:815-25. doi:10.1007/s00595-007-3734-y
-
(2008)
Surg Today
, vol.38
, pp. 815-825
-
-
Pan, X.-C.1
Guo, L.2
Deng, Y.-B.3
Naruse, K.4
Kimura, H.5
Sugawara, Y.6
-
130
-
-
10744223143
-
Simultaneous blockade of co-stimulatory signals, CD28 and ICOS, induced a stable tolerance in rat heart transplantation
-
Guo L, Fujino M, Kimura H, Funeshima N, Kitazawa Y, Harihara Y, et al. Simultaneous blockade of co-stimulatory signals, CD28 and ICOS, induced a stable tolerance in rat heart transplantation. Transpl Immunol (2003) 12:41-8. doi:10.1016/S0966-3274(03)00016-9
-
(2003)
Transpl Immunol
, vol.12
, pp. 41-48
-
-
Guo, L.1
Fujino, M.2
Kimura, H.3
Funeshima, N.4
Kitazawa, Y.5
Harihara, Y.6
-
131
-
-
84925296544
-
A pilot trial targeting the ICOS-ICOS-L pathway in nonhuman primate kidney transplantation
-
Lo DJ, Anderson DJ, Song M, Leopardi F, Farris AB, Strobert E, et al. A pilot trial targeting the ICOS-ICOS-L pathway in nonhuman primate kidney transplantation. Am J Transplant (2015) 15:984-92. doi:10.1111/ajt.13100
-
(2015)
Am J Transplant
, vol.15
, pp. 984-992
-
-
Lo, D.J.1
Anderson, D.J.2
Song, M.3
Leopardi, F.4
Farris, A.B.5
Strobert, E.6
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