Low-level hypermutation in T cell-independent germinal centers compared with high mutation rates associated with T cell-dependent germinal centers

Journal of Experimental Medicine

Volumn 195, Issue 3, 2002, Pages 383-389

  Toellner, Kai Michael ^a   Jenkinson, William E ^a   Taylor, Dale R ^a   Khan, Mahmood ^a   Sze, Daniel M Y ^a   Sansom, David M ^a   Vinuesa, Carola G ^a   MacLennan, Ian C M ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Adoptive cell transfer; DNA mutational analysis; Immunization; Plasma cells; Spleen

Indexed keywords

ANTIGEN; POLYSACCHARIDE; PROTEIN NP; UNCLASSIFIED DRUG;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; B LYMPHOCYTE; CELL INTERACTION; CONTROLLED STUDY; GENE MUTATION; GERMINAL CENTER; IMMUNIZATION; IMMUNOGLOBULIN VARIABLE REGION; MOUSE; MUTATION RATE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMA CELL; PRIORITY JOURNAL; SPLEEN; T LYMPHOCYTE; TRANSGENIC MOUSE;

ADOPTIVE TRANSFER; ANIMALS; ANIMALS, CONGENIC; ANTIGENS, T-INDEPENDENT; B-LYMPHOCYTES; BASE SEQUENCE; DNA; GERMINAL CENTER; IMMUNIZATION; IMMUNOGLOBULIN VARIABLE REGION; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; MUTATION; NITROPHENOLS; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 0037017391     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20011112     Document Type: Article

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