메뉴 건너뛰기




Volumn 15, Issue 4, 2015, Pages 984-992

A pilot trial targeting the icos-icos-l pathway in nonhuman primate kidney transplantation

Author keywords

animal models: nonhuman primate; costimulation; immunosuppression immune modulation; kidney transplantation nephrology; translational research science

Indexed keywords

BELATACEPT; CD28 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; HLA B7 ANTIGEN; HYBRID PROTEIN; INDUCIBLE T CELL COSTIMULATOR; INDUCIBLE T CELL COSTIMULATOR LIGAND; INDUCIBLE T CELL COSTIMULATOR LIGAND IMMUNOGLOBULIN FUSION PROTEIN; UNCLASSIFIED DRUG; ABATACEPT;

EID: 84925296544     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/ajt.13100     Document Type: Article
Times cited : (30)

References (35)
  • 1
    • 84886791910 scopus 로고    scopus 로고
    • Long-term belatacept exposure maintains efficacy and safety at 5 years: Results from the long-term extension of the BENEFIT study
    • Rostaing L, Vincenti F, Grinyo J, et al. Long-term belatacept exposure maintains efficacy and safety at 5 years: Results from the long-term extension of the BENEFIT study. Am J Transplant 2013; 13: 2875-2883.
    • (2013) Am J Transplant , vol.13 , pp. 2875-2883
    • Rostaing, L.1    Vincenti, F.2    Grinyo, J.3
  • 2
    • 79955544132 scopus 로고    scopus 로고
    • Belatacept-based regimens are associated with improved cardiovascular and metabolic risk factors compared with cyclosporine in kidney transplant recipients (BENEFIT and BENEFIT-EXT studies)
    • Vanrenterghem Y, Bresnahan B, Campistol J, et al. Belatacept-based regimens are associated with improved cardiovascular and metabolic risk factors compared with cyclosporine in kidney transplant recipients (BENEFIT and BENEFIT-EXT studies). Transplantation 2011; 91: 976-983.
    • (2011) Transplantation , vol.91 , pp. 976-983
    • Vanrenterghem, Y.1    Bresnahan, B.2    Campistol, J.3
  • 3
    • 76949101581 scopus 로고    scopus 로고
    • A phase III study of belatacept-based immunosuppression regimens versus cyclosporine in renal transplant recipients (BENEFIT study)
    • Vincenti F, Charpentier B, Vanrenterghem Y, et al. A phase III study of belatacept-based immunosuppression regimens versus cyclosporine in renal transplant recipients (BENEFIT study). Am J Transplant 2010; 10: 535-546.
    • (2010) Am J Transplant , vol.10 , pp. 535-546
    • Vincenti, F.1    Charpentier, B.2    Vanrenterghem, Y.3
  • 4
    • 0033590502 scopus 로고    scopus 로고
    • ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28
    • Hutloff A, Dittrich AM, Beier KC, et al. ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28. Nature 1999; 397: 263-266.
    • (1999) Nature , vol.397 , pp. 263-266
    • Hutloff, A.1    Dittrich, A.M.2    Beier, K.C.3
  • 5
    • 0033576707 scopus 로고    scopus 로고
    • T-cell co-stimulation through B7RP-1 and ICOS
    • Yoshinaga SK, Whoriskey JS, Khare SD, et al. T-cell co-stimulation through B7RP-1 and ICOS. Nature 1999; 402: 827-832.
    • (1999) Nature , vol.402 , pp. 827-832
    • Yoshinaga, S.K.1    Whoriskey, J.S.2    Khare, S.D.3
  • 6
    • 0034193043 scopus 로고    scopus 로고
    • Characterization of human inducible costimulator ligand expression and function
    • Aicher A, Hayden-Ledbetter M, Brady WA, et al. Characterization of human inducible costimulator ligand expression and function. J Immunol 2000; 164: 4689-4696.
    • (2000) J Immunol , vol.164 , pp. 4689-4696
    • Aicher, A.1    Hayden-Ledbetter, M.2    Brady, W.A.3
  • 7
    • 0033212778 scopus 로고    scopus 로고
    • B7h, a novel costimulatory homolog of B7.1 and B7.2, is induced by TNFalpha
    • Swallow MM, Wallin JJ, Sha WC., B7h, a novel costimulatory homolog of B7.1 and B7.2, is induced by TNFalpha. Immunity 1999; 11: 423-432.
    • (1999) Immunity , vol.11 , pp. 423-432
    • Swallow, M.M.1    Wallin, J.J.2    Sha, W.C.3
  • 8
    • 0033696961 scopus 로고    scopus 로고
    • The CD28-related molecule ICOS is required for effective T cell-dependent immune responses
    • Coyle AJ, Lehar S, Lloyd C, et al. The CD28-related molecule ICOS is required for effective T cell-dependent immune responses. Immunity 2000; 13: 95-105.
    • (2000) Immunity , vol.13 , pp. 95-105
    • Coyle, A.J.1    Lehar, S.2    Lloyd, C.3
  • 9
    • 0035804268 scopus 로고    scopus 로고
    • ICOS is critical for CD40-mediated antibody class switching
    • McAdam AJ, Greenwald RJ, Levin MA, et al. ICOS is critical for CD40-mediated antibody class switching. Nature 2001; 409: 102-105.
    • (2001) Nature , vol.409 , pp. 102-105
    • McAdam, A.J.1    Greenwald, R.J.2    Levin, M.A.3
  • 10
    • 0035804269 scopus 로고    scopus 로고
    • ICOS is essential for effective T-helper-cell responses
    • Tafuri A, Shahinian A, Bladt F, et al. ICOS is essential for effective T-helper-cell responses. Nature 2001; 409: 105-109.
    • (2001) Nature , vol.409 , pp. 105-109
    • Tafuri, A.1    Shahinian, A.2    Bladt, F.3
  • 11
    • 0034917195 scopus 로고    scopus 로고
    • Importance of ICOS-B7RP-1 costimulation in acute and chronic allograft rejection
    • Ozkaynak E, Gao W, Shemmeri N, et al. Importance of ICOS-B7RP-1 costimulation in acute and chronic allograft rejection. Nat Immunol 2001; 2: 591-596.
    • (2001) Nat Immunol , vol.2 , pp. 591-596
    • Ozkaynak, E.1    Gao, W.2    Shemmeri, N.3
  • 12
    • 33644872830 scopus 로고    scopus 로고
    • Alloimmunity in primate heart recipients with CD154 blockade: Evidence for alternative costimulation mechanisms
    • Azimzadeh AM, Pfeiffer S, Wu G, et al. Alloimmunity in primate heart recipients with CD154 blockade: Evidence for alternative costimulation mechanisms. Transplantation 2006; 81: 255-264.
    • (2006) Transplantation , vol.81 , pp. 255-264
    • Azimzadeh, A.M.1    Pfeiffer, S.2    Wu, G.3
  • 13
    • 11144354562 scopus 로고    scopus 로고
    • Multiple combination therapies involving blockade of ICOS/B7RP-1 costimulation facilitate long-term islet allograft survival
    • Nanji SA, Hancock WW, Anderson CC, et al. Multiple combination therapies involving blockade of ICOS/B7RP-1 costimulation facilitate long-term islet allograft survival. Am J Transplant 2004; 4: 526-536.
    • (2004) Am J Transplant , vol.4 , pp. 526-536
    • Nanji, S.A.1    Hancock, W.W.2    Anderson, C.C.3
  • 14
    • 0041861305 scopus 로고    scopus 로고
    • Glomerular infiltration by CXCR3+ ICOS+ activated T cells in chronic allograft nephropathy with transplant glomerulopathy
    • Akalin E, Dikman S, Murphy B, Bromberg JS, Hancock WW., Glomerular infiltration by CXCR3+ ICOS+ activated T cells in chronic allograft nephropathy with transplant glomerulopathy. Am J Transplant 2003; 3: 1116-1120.
    • (2003) Am J Transplant , vol.3 , pp. 1116-1120
    • Akalin, E.1    Dikman, S.2    Murphy, B.3    Bromberg, J.S.4    Hancock, W.W.5
  • 15
    • 48349097977 scopus 로고    scopus 로고
    • Donor-reactive CD8 memory T cells infiltrate cardiac allografts within 24-h posttransplant in naive recipients
    • Schenk AD, Nozaki T, Rabant M, Valujskikh A, Fairchild RL., Donor-reactive CD8 memory T cells infiltrate cardiac allografts within 24-h posttransplant in naive recipients. Am J Transplant 2008; 8: 1652-1661.
    • (2008) Am J Transplant , vol.8 , pp. 1652-1661
    • Schenk, A.D.1    Nozaki, T.2    Rabant, M.3    Valujskikh, A.4    Fairchild, R.L.5
  • 16
    • 58049211975 scopus 로고    scopus 로고
    • Effector functions of donor-reactive CD8 memory T cells are dependent on ICOS induced during division in cardiac grafts
    • Schenk AD, Gorbacheva V, Rabant M, Fairchild RL, Valujskikh A., Effector functions of donor-reactive CD8 memory T cells are dependent on ICOS induced during division in cardiac grafts. Am J Transplant 2009; 9: 64-73.
    • (2009) Am J Transplant , vol.9 , pp. 64-73
    • Schenk, A.D.1    Gorbacheva, V.2    Rabant, M.3    Fairchild, R.L.4    Valujskikh, A.5
  • 17
    • 0037469060 scopus 로고    scopus 로고
    • Induction of immunologic tolerance to cardiac allograft by simultaneous blockade of inducible co-stimulator and cytotoxic T-lymphocyte antigen 4 pathway
    • Kosuge H, Suzuki J, Gotoh R, et al. Induction of immunologic tolerance to cardiac allograft by simultaneous blockade of inducible co-stimulator and cytotoxic T-lymphocyte antigen 4 pathway. Transplantation 2003; 75: 1374-1379.
    • (2003) Transplantation , vol.75 , pp. 1374-1379
    • Kosuge, H.1    Suzuki, J.2    Gotoh, R.3
  • 18
    • 39649125383 scopus 로고    scopus 로고
    • ICOS-dependent and -independent functions of memory CD4 T cells in allograft rejection
    • Zhang QW, Rabant M, Schenk A, Valujskikh A., ICOS-dependent and -independent functions of memory CD4 T cells in allograft rejection. Am J Transplant 2008; 8: 497-506.
    • (2008) Am J Transplant , vol.8 , pp. 497-506
    • Zhang, Q.W.1    Rabant, M.2    Schenk, A.3    Valujskikh, A.4
  • 19
    • 0043245118 scopus 로고    scopus 로고
    • The role of the ICOS-B7h T cell costimulatory pathway in transplantation immunity
    • Harada H, Salama AD, Sho M, et al. The role of the ICOS-B7h T cell costimulatory pathway in transplantation immunity. J Clin Invest 2003; 112: 234-243.
    • (2003) J Clin Invest , vol.112 , pp. 234-243
    • Harada, H.1    Salama, A.D.2    Sho, M.3
  • 20
    • 0038752607 scopus 로고    scopus 로고
    • Interaction between ICOS-B7RP1 and B7-CD28 costimulatory pathways in alloimmune responses in vivo
    • Salama AD, Yuan X, Nayer A, et al. Interaction between ICOS-B7RP1 and B7-CD28 costimulatory pathways in alloimmune responses in vivo. Am J Transplant 2003; 3: 390-395.
    • (2003) Am J Transplant , vol.3 , pp. 390-395
    • Salama, A.D.1    Yuan, X.2    Nayer, A.3
  • 21
    • 20844439036 scopus 로고    scopus 로고
    • Role of the ICOS-B7h costimulatory pathway in the pathophysiology of chronic allograft rejection
    • Kashizuka H, Sho M, Nomi T, et al. Role of the ICOS-B7h costimulatory pathway in the pathophysiology of chronic allograft rejection. Transplantation 2005; 79: 1045-1050.
    • (2005) Transplantation , vol.79 , pp. 1045-1050
    • Kashizuka, H.1    Sho, M.2    Nomi, T.3
  • 22
    • 12644262358 scopus 로고    scopus 로고
    • CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates
    • Kirk AD, Harlan DM, Armstrong NN, et al. CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates. Proc Natl Acad Sci USA 1997; 94: 8789-8794.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 8789-8794
    • Kirk, A.D.1    Harlan, D.M.2    Armstrong, N.N.3
  • 23
    • 0032910625 scopus 로고    scopus 로고
    • The Banff 97 working classification of renal allograft pathology
    • Racusen LC, Solez K, Colvin RB, et al. The Banff 97 working classification of renal allograft pathology. Kidney Int 1999; 55: 713-723.
    • (1999) Kidney Int , vol.55 , pp. 713-723
    • Racusen, L.C.1    Solez, K.2    Colvin, R.B.3
  • 24
    • 0036135578 scopus 로고    scopus 로고
    • Development and homeostasis of T cell memory in rhesus macaque
    • Pitcher CJ, Hagen SI, Walker JM, et al. Development and homeostasis of T cell memory in rhesus macaque. J Immunol 2002; 168: 29-43.
    • (2002) J Immunol , vol.168 , pp. 29-43
    • Pitcher, C.J.1    Hagen, S.I.2    Walker, J.M.3
  • 25
    • 78650899002 scopus 로고    scopus 로고
    • Selective targeting of human alloresponsive CD8+ effector memory T cells based on CD2 expression
    • Lo DJ, Weaver TA, Stempora L, et al. Selective targeting of human alloresponsive CD8+ effector memory T cells based on CD2 expression. Am J Transplant 2011; 11: 22-33.
    • (2011) Am J Transplant , vol.11 , pp. 22-33
    • Lo, D.J.1    Weaver, T.A.2    Stempora, L.3
  • 26
    • 0037197971 scopus 로고    scopus 로고
    • Recall and propagation of allospecific memory T cells independent of secondary lymphoid organs
    • Chalasani G, Dai Z, Konieczny BT, Baddoura FK, Lakkis FG., Recall and propagation of allospecific memory T cells independent of secondary lymphoid organs. Proc Natl Acad Sci USA 2002; 99: 6175-6180.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 6175-6180
    • Chalasani, G.1    Dai, Z.2    Konieczny, B.T.3    Baddoura, F.K.4    Lakkis, F.G.5
  • 27
    • 0034658407 scopus 로고    scopus 로고
    • Human vascular endothelial cells stimulate memory but not naive CD8+ T cells to differentiate into CTL retaining an early activation phenotype
    • Dengler TJ, Pober JS., Human vascular endothelial cells stimulate memory but not naive CD8+ T cells to differentiate into CTL retaining an early activation phenotype. J Immunol 2000; 164: 5146-5155.
    • (2000) J Immunol , vol.164 , pp. 5146-5155
    • Dengler, T.J.1    Pober, J.S.2
  • 28
    • 0034922160 scopus 로고    scopus 로고
    • The costimulatory molecule ICOS plays an important role in the immunopathogenesis of EAE
    • Rottman JB, Smith T, Tonra JR, et al. The costimulatory molecule ICOS plays an important role in the immunopathogenesis of EAE. Nat Immunol 2001; 2: 605-611.
    • (2001) Nat Immunol , vol.2 , pp. 605-611
    • Rottman, J.B.1    Smith, T.2    Tonra, J.R.3
  • 29
    • 0034912508 scopus 로고    scopus 로고
    • ICOS costimulation: It's not just for TH2 cells anymore
    • Sperling AI, Bluestone JA., ICOS costimulation: It's not just for TH2 cells anymore. Nat Immunol 2001; 2: 573-574.
    • (2001) Nat Immunol , vol.2 , pp. 573-574
    • Sperling, A.I.1    Bluestone, J.A.2
  • 30
    • 40449116396 scopus 로고    scopus 로고
    • ICOS controls the pool size of effector-memory and regulatory T cells
    • Burmeister Y, Lischke T, Dahler AC, et al. ICOS controls the pool size of effector-memory and regulatory T cells. J Immunol 2008; 180: 774-782.
    • (2008) J Immunol , vol.180 , pp. 774-782
    • Burmeister, Y.1    Lischke, T.2    Dahler, A.C.3
  • 31
    • 0036732461 scopus 로고    scopus 로고
    • Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity
    • Akbari O, Freeman GJ, Meyer EH, et al. Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity. Nat Med 2002; 8: 1024-1032.
    • (2002) Nat Med , vol.8 , pp. 1024-1032
    • Akbari, O.1    Freeman, G.J.2    Meyer, E.H.3
  • 32
    • 84891607732 scopus 로고    scopus 로고
    • ICOS regulates the generation and function of human CD4+ Treg in a CTLA-4 dependent manner
    • Zheng J, Chan PL, Liu Y, et al. ICOS regulates the generation and function of human CD4+ Treg in a CTLA-4 dependent manner. PLoS One 2013; 8: e82203.
    • (2013) PLoS One , vol.8 , pp. e82203
    • Zheng, J.1    Chan, P.L.2    Liu, Y.3
  • 33
    • 84873096090 scopus 로고    scopus 로고
    • Belatacept and sirolimus prolong nonhuman primate renal allograft survival without a requirement for memory T cell depletion
    • Lo DJ, Anderson DJ, Weaver TA, et al. Belatacept and sirolimus prolong nonhuman primate renal allograft survival without a requirement for memory T cell depletion. Am J Transplant 2013; 13: 320-328.
    • (2013) Am J Transplant , vol.13 , pp. 320-328
    • Lo, D.J.1    Anderson, D.J.2    Weaver, T.A.3
  • 34
    • 84893732562 scopus 로고    scopus 로고
    • 2B4 (CD244) induced by selective CD28 blockade functionally regulates allograft-specific CD8+ T cell responses
    • Liu D, Krummey SM, Badell IR, et al. 2B4 (CD244) induced by selective CD28 blockade functionally regulates allograft-specific CD8+ T cell responses. J Exp Med 2014; 211: 297-311.
    • (2014) J Exp Med , vol.211 , pp. 297-311
    • Liu, D.1    Krummey, S.M.2    Badell, I.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.