-
1
-
-
84886791910
-
Long-term belatacept exposure maintains efficacy and safety at 5 years: Results from the long-term extension of the BENEFIT study
-
Rostaing L, Vincenti F, Grinyo J, et al. Long-term belatacept exposure maintains efficacy and safety at 5 years: Results from the long-term extension of the BENEFIT study. Am J Transplant 2013; 13: 2875-2883.
-
(2013)
Am J Transplant
, vol.13
, pp. 2875-2883
-
-
Rostaing, L.1
Vincenti, F.2
Grinyo, J.3
-
2
-
-
79955544132
-
Belatacept-based regimens are associated with improved cardiovascular and metabolic risk factors compared with cyclosporine in kidney transplant recipients (BENEFIT and BENEFIT-EXT studies)
-
Vanrenterghem Y, Bresnahan B, Campistol J, et al. Belatacept-based regimens are associated with improved cardiovascular and metabolic risk factors compared with cyclosporine in kidney transplant recipients (BENEFIT and BENEFIT-EXT studies). Transplantation 2011; 91: 976-983.
-
(2011)
Transplantation
, vol.91
, pp. 976-983
-
-
Vanrenterghem, Y.1
Bresnahan, B.2
Campistol, J.3
-
3
-
-
76949101581
-
A phase III study of belatacept-based immunosuppression regimens versus cyclosporine in renal transplant recipients (BENEFIT study)
-
Vincenti F, Charpentier B, Vanrenterghem Y, et al. A phase III study of belatacept-based immunosuppression regimens versus cyclosporine in renal transplant recipients (BENEFIT study). Am J Transplant 2010; 10: 535-546.
-
(2010)
Am J Transplant
, vol.10
, pp. 535-546
-
-
Vincenti, F.1
Charpentier, B.2
Vanrenterghem, Y.3
-
4
-
-
0033590502
-
ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28
-
Hutloff A, Dittrich AM, Beier KC, et al. ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28. Nature 1999; 397: 263-266.
-
(1999)
Nature
, vol.397
, pp. 263-266
-
-
Hutloff, A.1
Dittrich, A.M.2
Beier, K.C.3
-
5
-
-
0033576707
-
T-cell co-stimulation through B7RP-1 and ICOS
-
Yoshinaga SK, Whoriskey JS, Khare SD, et al. T-cell co-stimulation through B7RP-1 and ICOS. Nature 1999; 402: 827-832.
-
(1999)
Nature
, vol.402
, pp. 827-832
-
-
Yoshinaga, S.K.1
Whoriskey, J.S.2
Khare, S.D.3
-
6
-
-
0034193043
-
Characterization of human inducible costimulator ligand expression and function
-
Aicher A, Hayden-Ledbetter M, Brady WA, et al. Characterization of human inducible costimulator ligand expression and function. J Immunol 2000; 164: 4689-4696.
-
(2000)
J Immunol
, vol.164
, pp. 4689-4696
-
-
Aicher, A.1
Hayden-Ledbetter, M.2
Brady, W.A.3
-
7
-
-
0033212778
-
B7h, a novel costimulatory homolog of B7.1 and B7.2, is induced by TNFalpha
-
Swallow MM, Wallin JJ, Sha WC., B7h, a novel costimulatory homolog of B7.1 and B7.2, is induced by TNFalpha. Immunity 1999; 11: 423-432.
-
(1999)
Immunity
, vol.11
, pp. 423-432
-
-
Swallow, M.M.1
Wallin, J.J.2
Sha, W.C.3
-
8
-
-
0033696961
-
The CD28-related molecule ICOS is required for effective T cell-dependent immune responses
-
Coyle AJ, Lehar S, Lloyd C, et al. The CD28-related molecule ICOS is required for effective T cell-dependent immune responses. Immunity 2000; 13: 95-105.
-
(2000)
Immunity
, vol.13
, pp. 95-105
-
-
Coyle, A.J.1
Lehar, S.2
Lloyd, C.3
-
9
-
-
0035804268
-
ICOS is critical for CD40-mediated antibody class switching
-
McAdam AJ, Greenwald RJ, Levin MA, et al. ICOS is critical for CD40-mediated antibody class switching. Nature 2001; 409: 102-105.
-
(2001)
Nature
, vol.409
, pp. 102-105
-
-
McAdam, A.J.1
Greenwald, R.J.2
Levin, M.A.3
-
10
-
-
0035804269
-
ICOS is essential for effective T-helper-cell responses
-
Tafuri A, Shahinian A, Bladt F, et al. ICOS is essential for effective T-helper-cell responses. Nature 2001; 409: 105-109.
-
(2001)
Nature
, vol.409
, pp. 105-109
-
-
Tafuri, A.1
Shahinian, A.2
Bladt, F.3
-
11
-
-
0034917195
-
Importance of ICOS-B7RP-1 costimulation in acute and chronic allograft rejection
-
Ozkaynak E, Gao W, Shemmeri N, et al. Importance of ICOS-B7RP-1 costimulation in acute and chronic allograft rejection. Nat Immunol 2001; 2: 591-596.
-
(2001)
Nat Immunol
, vol.2
, pp. 591-596
-
-
Ozkaynak, E.1
Gao, W.2
Shemmeri, N.3
-
12
-
-
33644872830
-
Alloimmunity in primate heart recipients with CD154 blockade: Evidence for alternative costimulation mechanisms
-
Azimzadeh AM, Pfeiffer S, Wu G, et al. Alloimmunity in primate heart recipients with CD154 blockade: Evidence for alternative costimulation mechanisms. Transplantation 2006; 81: 255-264.
-
(2006)
Transplantation
, vol.81
, pp. 255-264
-
-
Azimzadeh, A.M.1
Pfeiffer, S.2
Wu, G.3
-
13
-
-
11144354562
-
Multiple combination therapies involving blockade of ICOS/B7RP-1 costimulation facilitate long-term islet allograft survival
-
Nanji SA, Hancock WW, Anderson CC, et al. Multiple combination therapies involving blockade of ICOS/B7RP-1 costimulation facilitate long-term islet allograft survival. Am J Transplant 2004; 4: 526-536.
-
(2004)
Am J Transplant
, vol.4
, pp. 526-536
-
-
Nanji, S.A.1
Hancock, W.W.2
Anderson, C.C.3
-
14
-
-
0041861305
-
Glomerular infiltration by CXCR3+ ICOS+ activated T cells in chronic allograft nephropathy with transplant glomerulopathy
-
Akalin E, Dikman S, Murphy B, Bromberg JS, Hancock WW., Glomerular infiltration by CXCR3+ ICOS+ activated T cells in chronic allograft nephropathy with transplant glomerulopathy. Am J Transplant 2003; 3: 1116-1120.
-
(2003)
Am J Transplant
, vol.3
, pp. 1116-1120
-
-
Akalin, E.1
Dikman, S.2
Murphy, B.3
Bromberg, J.S.4
Hancock, W.W.5
-
15
-
-
48349097977
-
Donor-reactive CD8 memory T cells infiltrate cardiac allografts within 24-h posttransplant in naive recipients
-
Schenk AD, Nozaki T, Rabant M, Valujskikh A, Fairchild RL., Donor-reactive CD8 memory T cells infiltrate cardiac allografts within 24-h posttransplant in naive recipients. Am J Transplant 2008; 8: 1652-1661.
-
(2008)
Am J Transplant
, vol.8
, pp. 1652-1661
-
-
Schenk, A.D.1
Nozaki, T.2
Rabant, M.3
Valujskikh, A.4
Fairchild, R.L.5
-
16
-
-
58049211975
-
Effector functions of donor-reactive CD8 memory T cells are dependent on ICOS induced during division in cardiac grafts
-
Schenk AD, Gorbacheva V, Rabant M, Fairchild RL, Valujskikh A., Effector functions of donor-reactive CD8 memory T cells are dependent on ICOS induced during division in cardiac grafts. Am J Transplant 2009; 9: 64-73.
-
(2009)
Am J Transplant
, vol.9
, pp. 64-73
-
-
Schenk, A.D.1
Gorbacheva, V.2
Rabant, M.3
Fairchild, R.L.4
Valujskikh, A.5
-
17
-
-
0037469060
-
Induction of immunologic tolerance to cardiac allograft by simultaneous blockade of inducible co-stimulator and cytotoxic T-lymphocyte antigen 4 pathway
-
Kosuge H, Suzuki J, Gotoh R, et al. Induction of immunologic tolerance to cardiac allograft by simultaneous blockade of inducible co-stimulator and cytotoxic T-lymphocyte antigen 4 pathway. Transplantation 2003; 75: 1374-1379.
-
(2003)
Transplantation
, vol.75
, pp. 1374-1379
-
-
Kosuge, H.1
Suzuki, J.2
Gotoh, R.3
-
18
-
-
39649125383
-
ICOS-dependent and -independent functions of memory CD4 T cells in allograft rejection
-
Zhang QW, Rabant M, Schenk A, Valujskikh A., ICOS-dependent and -independent functions of memory CD4 T cells in allograft rejection. Am J Transplant 2008; 8: 497-506.
-
(2008)
Am J Transplant
, vol.8
, pp. 497-506
-
-
Zhang, Q.W.1
Rabant, M.2
Schenk, A.3
Valujskikh, A.4
-
19
-
-
0043245118
-
The role of the ICOS-B7h T cell costimulatory pathway in transplantation immunity
-
Harada H, Salama AD, Sho M, et al. The role of the ICOS-B7h T cell costimulatory pathway in transplantation immunity. J Clin Invest 2003; 112: 234-243.
-
(2003)
J Clin Invest
, vol.112
, pp. 234-243
-
-
Harada, H.1
Salama, A.D.2
Sho, M.3
-
20
-
-
0038752607
-
Interaction between ICOS-B7RP1 and B7-CD28 costimulatory pathways in alloimmune responses in vivo
-
Salama AD, Yuan X, Nayer A, et al. Interaction between ICOS-B7RP1 and B7-CD28 costimulatory pathways in alloimmune responses in vivo. Am J Transplant 2003; 3: 390-395.
-
(2003)
Am J Transplant
, vol.3
, pp. 390-395
-
-
Salama, A.D.1
Yuan, X.2
Nayer, A.3
-
21
-
-
20844439036
-
Role of the ICOS-B7h costimulatory pathway in the pathophysiology of chronic allograft rejection
-
Kashizuka H, Sho M, Nomi T, et al. Role of the ICOS-B7h costimulatory pathway in the pathophysiology of chronic allograft rejection. Transplantation 2005; 79: 1045-1050.
-
(2005)
Transplantation
, vol.79
, pp. 1045-1050
-
-
Kashizuka, H.1
Sho, M.2
Nomi, T.3
-
22
-
-
12644262358
-
CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates
-
Kirk AD, Harlan DM, Armstrong NN, et al. CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates. Proc Natl Acad Sci USA 1997; 94: 8789-8794.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 8789-8794
-
-
Kirk, A.D.1
Harlan, D.M.2
Armstrong, N.N.3
-
23
-
-
0032910625
-
The Banff 97 working classification of renal allograft pathology
-
Racusen LC, Solez K, Colvin RB, et al. The Banff 97 working classification of renal allograft pathology. Kidney Int 1999; 55: 713-723.
-
(1999)
Kidney Int
, vol.55
, pp. 713-723
-
-
Racusen, L.C.1
Solez, K.2
Colvin, R.B.3
-
24
-
-
0036135578
-
Development and homeostasis of T cell memory in rhesus macaque
-
Pitcher CJ, Hagen SI, Walker JM, et al. Development and homeostasis of T cell memory in rhesus macaque. J Immunol 2002; 168: 29-43.
-
(2002)
J Immunol
, vol.168
, pp. 29-43
-
-
Pitcher, C.J.1
Hagen, S.I.2
Walker, J.M.3
-
25
-
-
78650899002
-
Selective targeting of human alloresponsive CD8+ effector memory T cells based on CD2 expression
-
Lo DJ, Weaver TA, Stempora L, et al. Selective targeting of human alloresponsive CD8+ effector memory T cells based on CD2 expression. Am J Transplant 2011; 11: 22-33.
-
(2011)
Am J Transplant
, vol.11
, pp. 22-33
-
-
Lo, D.J.1
Weaver, T.A.2
Stempora, L.3
-
26
-
-
0037197971
-
Recall and propagation of allospecific memory T cells independent of secondary lymphoid organs
-
Chalasani G, Dai Z, Konieczny BT, Baddoura FK, Lakkis FG., Recall and propagation of allospecific memory T cells independent of secondary lymphoid organs. Proc Natl Acad Sci USA 2002; 99: 6175-6180.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 6175-6180
-
-
Chalasani, G.1
Dai, Z.2
Konieczny, B.T.3
Baddoura, F.K.4
Lakkis, F.G.5
-
27
-
-
0034658407
-
Human vascular endothelial cells stimulate memory but not naive CD8+ T cells to differentiate into CTL retaining an early activation phenotype
-
Dengler TJ, Pober JS., Human vascular endothelial cells stimulate memory but not naive CD8+ T cells to differentiate into CTL retaining an early activation phenotype. J Immunol 2000; 164: 5146-5155.
-
(2000)
J Immunol
, vol.164
, pp. 5146-5155
-
-
Dengler, T.J.1
Pober, J.S.2
-
28
-
-
0034922160
-
The costimulatory molecule ICOS plays an important role in the immunopathogenesis of EAE
-
Rottman JB, Smith T, Tonra JR, et al. The costimulatory molecule ICOS plays an important role in the immunopathogenesis of EAE. Nat Immunol 2001; 2: 605-611.
-
(2001)
Nat Immunol
, vol.2
, pp. 605-611
-
-
Rottman, J.B.1
Smith, T.2
Tonra, J.R.3
-
29
-
-
0034912508
-
ICOS costimulation: It's not just for TH2 cells anymore
-
Sperling AI, Bluestone JA., ICOS costimulation: It's not just for TH2 cells anymore. Nat Immunol 2001; 2: 573-574.
-
(2001)
Nat Immunol
, vol.2
, pp. 573-574
-
-
Sperling, A.I.1
Bluestone, J.A.2
-
30
-
-
40449116396
-
ICOS controls the pool size of effector-memory and regulatory T cells
-
Burmeister Y, Lischke T, Dahler AC, et al. ICOS controls the pool size of effector-memory and regulatory T cells. J Immunol 2008; 180: 774-782.
-
(2008)
J Immunol
, vol.180
, pp. 774-782
-
-
Burmeister, Y.1
Lischke, T.2
Dahler, A.C.3
-
31
-
-
0036732461
-
Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity
-
Akbari O, Freeman GJ, Meyer EH, et al. Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity. Nat Med 2002; 8: 1024-1032.
-
(2002)
Nat Med
, vol.8
, pp. 1024-1032
-
-
Akbari, O.1
Freeman, G.J.2
Meyer, E.H.3
-
32
-
-
84891607732
-
ICOS regulates the generation and function of human CD4+ Treg in a CTLA-4 dependent manner
-
Zheng J, Chan PL, Liu Y, et al. ICOS regulates the generation and function of human CD4+ Treg in a CTLA-4 dependent manner. PLoS One 2013; 8: e82203.
-
(2013)
PLoS One
, vol.8
, pp. e82203
-
-
Zheng, J.1
Chan, P.L.2
Liu, Y.3
-
33
-
-
84873096090
-
Belatacept and sirolimus prolong nonhuman primate renal allograft survival without a requirement for memory T cell depletion
-
Lo DJ, Anderson DJ, Weaver TA, et al. Belatacept and sirolimus prolong nonhuman primate renal allograft survival without a requirement for memory T cell depletion. Am J Transplant 2013; 13: 320-328.
-
(2013)
Am J Transplant
, vol.13
, pp. 320-328
-
-
Lo, D.J.1
Anderson, D.J.2
Weaver, T.A.3
-
34
-
-
84893732562
-
2B4 (CD244) induced by selective CD28 blockade functionally regulates allograft-specific CD8+ T cell responses
-
Liu D, Krummey SM, Badell IR, et al. 2B4 (CD244) induced by selective CD28 blockade functionally regulates allograft-specific CD8+ T cell responses. J Exp Med 2014; 211: 297-311.
-
(2014)
J Exp Med
, vol.211
, pp. 297-311
-
-
Liu, D.1
Krummey, S.M.2
Badell, I.R.3
-
35
-
-
34447121306
-
New insights in CD28-independent allograft rejection
-
Habicht A, Najafian N, Yagita H, Sayegh MH, Clarkson MR., New insights in CD28-independent allograft rejection. Am J Transplant 2007; 7: 1917-1926.
-
(2007)
Am J Transplant
, vol.7
, pp. 1917-1926
-
-
Habicht, A.1
Najafian, N.2
Yagita, H.3
Sayegh, M.H.4
Clarkson, M.R.5
|