Role of ICOS versus CD28 in antiviral immunity

European Journal of Immunology

Volumn 32, Issue 12, 2002, Pages 3376-3385

  Bertram, Edward M ^a   Tafuri, Anna ^a   Shahinian, Arda ^a   Chan, Vera S F ^a   Hunziker, Lukas ^b   Recher, Mike ^b   Ohashi, Pamela S ^a   Mak, Tak W ^a   Watts, Tania H ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Constimulation; Knockout; Transgenic; Viral infection

Indexed keywords

CD28 ANTIGEN; CD8 ANTIGEN; CYTOKINE; INDUCIBLE COSTIMULATOR PROTEIN; REGULATOR PROTEIN; UNCLASSIFIED DRUG; VIRUS ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ANTIGEN SPECIFICITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; DISEASE SEVERITY; FEMALE; GERMINAL CENTER; HELPER CELL; IMMUNE RESPONSE; INFLUENZA; INFLUENZA VIRUS; LYMPHOCYTE COUNT; LYMPHOCYTE PROLIFERATION; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SYNTHESIS; SUPERINFECTION; SUPPRESSOR CELL; T LYMPHOCYTE ACTIVATION; VESICULAR STOMATITIS VIRUS; VIRUS IMMUNITY; WILD TYPE;

EID: 0036918725     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200212)32:12<3376::AID-IMMU3376>3.0.CO;2-Y     Document Type: Article

References (35)

1. Saloman, B. and Bluestone, J. A., Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation. Ann. Rev. Immunol. 2001. 19: 225-252.
2. Alegre, M. L., Frauwirth, K. A. and Thompson, C. B., T cell regulation by CD28 and CTLA-4. Nat. Rev Immunol 2001. 1: 220-228.
3. Sharpe, A. H. and Freeman, G. J., The B7-CD28 superfamily. Nat. Rev. Immunol. 2002. 2: 116-126.
4. Carreno, B. M. and Collins, M., The B7 family of ligands and its receptors: New pathways for costimulation and inhibition of immune responses. Ann. Rev. Immunol. 2002. 20: 29-53.
5. Boise, L. H., Minn, A. J., Noel, P. J., June, C. H., Accavitti, M. A., Lindsten, T. and Thompson, C. B., CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL. Immunity 1995. 3: 87-98.
6. Hutloff, A., Dittrich, A. M., Beier, K. C., Eljaschewitsch, B., Kraft, R., Anagnostopoulos, I. and Kroczek, R. A., ICOS is an inducible T cell co-stimulator structurally and functionally related to CD28. Nature 1999. 397: 263-265.
7. Brodie, D., Collins, A. V., Iaboni, A., Fennelly, J. A., Sparks, L. M., Xu, X. N., van der Merwe, P. A. and Davis, S. J., LICOS, a primordial costimulatory ligand? Cur. Biol. 2000. 10: 333-336.
8. Swallow, M. M., Wallin, J. J. and Sha, W. C., B7 h, a novel costimulatory homolog of B7.1 and B7.2, is induced by TNFalpha. Immunity 1999. 11: 423-432.
9. Yoshinaga, S. K., Whoriskey, J. S., Khare, S. D., Sarmiento, U., Guo, J., Horan, T., Shih, G., Zhang, M., Coccia, M. A., Kohno, T., Tafuri-Bladt, A., Brankow, D., Campbell, P., Chang, D., Chiu, L., Dai, T., Duncan, G., Elliott, G. S., Hui, A., McCabe, S. M., Scully, S., Shahinian, A., Shaklee, C. L., Van, G., Mak, T. W. and et al., T cell costimulation through B7RP-1 and ICOS. Nature 1999. 402; 827-832.
10. Dong, C., Juedes, A. E., Temann, U.-A., Shresta, S., Allison, J. P., Ruddle, N. H. and Flavell, R. A., ICOS co-stimulatory receptor is essential for T cell activation and function. Nature 2001. 409: 97-101.
11. McAdam, A. J., Greenwald, R. J., Levin, M. A., Chernova, T., Malenkovich, N., Ling, V., Freeman, G. J. and Sharpe, A. H., ICOS is critical for CD40-mediated antibody class switching. Nature 2001. 409: 102-105.
12. Tafuri, A., Shahinian, A., Bladt, F., Boucher, L.-M., Bouchard, D., Chan, V. S. F., Duncan, G., Odermatt, B., Ho, A., Itie, A., Horan, T., Whoriskey, J. S., Pawson, T., Penninger, J. M., Ohashi, P. S. and Mak, T. W., ICOS is essential for effective T-helper-cell responses. Nature 2001. 409: 105-109.
13. Gonzalo, J. A., Tian, J., Delaney, T., Corcoran, J., Rottman, J. B., Lora, J., Al-Garawi, A., Kroczek, R., Gutierrez-Ramos, J. C. and Coyle, A. J., ICOS is critical for T helper cell-mediated lung mucosal inflammatory responses. Nat. Immunol. 2001. 2: 597-604.
14. Rottman, J. B., Smith, T., Tonra, J. R., Ganley, K., Bloom, T., Silva, R., Pierce, B., Gutierrez-Ramos, J. C., Ozkaynak, E. and Coyle, A. J., The costimulatory molecule ICOS plays an important role in the immunopathogenesis of EAE. Nat. Immunol. 2001. 2: 605-611.
15. Coyle, A. J., Lehar, S., Lloyd, C., Tian, J., Delaney, T., Manning, S., Nguyen, T., Burwell, T., Schneider, H., Gonzalo, J. A., Gosselin, M., Owen, L. R., Rudd, C. E. and Gutierrez-Ramos, J. C., The CD28-related molecule ICOS is required for effective T cell-dependent immune responses. Immunity. 13: 95-105.
16. Tesciuba, A. G., Subudhi, S., Rother, R. P., Faas, S. J., Frantz, A. M., Elliot, D., Weinstock, J., Matis, L. A., Bluestone, J. A. and Sperling, A. I., Inducible costimulator regulates Th2-mediated inflammation, but not Th2 differentiation, in a model of allergic airway disease. J. Immunol. 2001. 167: 1996-2003.
17. Greenwald, R. J., McAdam, A. J., Van der Woude, D., Satoskar, A. R. and Sharpe, A. H., Cutting edge: Inducible costimulator protein regulates both Th1 and Th2 responses to cutaneous leishmaniasis. J. Immunol. 2002. 168: 991-995.
18. Kopf, M., Coyle, A. J., Schmitz, N., Barner, M., Oxenius, A., Gallimore, A., Gutierrez-Ramos, J. C. and Bachmann, M. F., Inducible costimulator protein (ICOS) controls T helper cell subset polarization after virus and parasite infection. J. Exp. Med. 2000. 192: 53-61.
19. Ozkaynak, E., Gao, W., Shemmeri, N., Wang, C., Gutierrez-Ramos, J. C., Amaral, J., Qin, S., Rottman, J. B., Coyle, A. J. and Hancock, W. W., Importance of ICOS-B7RP-1 costimulation in acute and chronic allograft rejection. Nat. Immunol. 2001. 2: 591-596.
20. + T cell responses by ICOS/B7 h costimulation. J. Immunol. 2001. 167: 132-139.
21. + T lymphocytes in vivo. J. Exp. Med. 2001. 194: 1339-1348.
22. Bertram, E. M., Lau, P. and Watts, T. H., Temporal segregation of CD28 versus 4-1BB1-mediated costimulation: 4-1BBL influences T cell numbers late in the primary response and regulates the size of the memory response following influenza infection. J. Immunol. 2002. 168: 3777-3785.
23. DeBenedette, M. A., Wen, T., Bachmann, M. F., Ohashi, P. S., Barber, B. H., Stocking, K. L., Peschon, J. J. and Watts, T. H., Analysis of 4-1BB ligand-deficient mice and of mice lacking both 4-1BB ligand and CD28 reveals a role for 4-1BB ligand in skin allograft rejection and in the cytotoxic T cell response to influenza virus. J. Immunol. 1999. 163: 4833-4841.
24. Townsend, A. R., Rothbard, J., Gotch, F., Bahadur, G., Wraith, D. and McMichael, A. J., The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides. Cell 1986. 44: 959-968.
25. Shahinian, A., Pfeffer, K., Lee, K. P., Kundig, T. M., Kishihara, K., Wakeham, A., Kawai, K., Ohashi, P. S., Thompson, C. B. and Mak, T. W., Differential T cell costimulatory requirements in CD28-deficient mice. Science 1993. 261: 609-612.
26. Kundig, T. M., Shahinian, A., Kawai, K., Mittrucker, H. W., Sebzda, E., Bachmann, M. F., Mak, T. W. and Ohashi, P. S., Duration of TCR stimulation determines costimulatory requirement of T cells. Immunity 1996. 5; 41-52.
27. + T cells in primary and secondary influenza pneumonia. Immunity 1998. 8: 683-691.
28. + T cell response to readily eliminated and persistent viruses. Philos. Trans. R. Soc. Lond. B 2000. 355: 1093-1101.
29. -/- mice. J. Virol. 2000. 74: 9762-9765.
30. Battegay, M., Moskophidis, D., Rahemtulla, A., Hengartner, H., Mak,T. W. and Zinkernagel, R. M., Enhanced establishment of a virus carrier state in adult CD4+ T cell-deficient mice. J. Virol. 1994. 68; 4700-4704.
31. + cytotoxic T cell responses during chronic viral infection. J. Virol. 1994. 68; 8056-8063.
32. von Herrath, M. G., Yokoyama, M., Dockter, J., Oldstone, M. B. and Whitton, J. L., CD4-deficient mice have reduced levels of memory cytotoxic T lymphocytes after immunization and show diminished resistance to subsequent virus challenge. J. Virol. 1996. 70: 1072-1079.
33. Kalams, S. A. and Walker, B. D., The critical need for CD4 help in maintaining effective cytotoxic T lymphocyte responses. J. Exp. Med. 1998. 188: 2199-2204.
34. -/- mice. J. Immunol. 2000. 164: 768-778.
35. Uger, R. A. and Barber, B. H., Creating CTL targets with epitope-linked β2-microglobulin constructs. J. Immunol. 1998. 160; 1598-1605.