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Volumn 189, Issue 6, 2012, Pages 2793-2804

ICOS-expressing CD4 T cells induced via TLR4 in the nasal mucosa are capable of inhibiting experimental allergic asthma

Author keywords

[No Author keywords available]

Indexed keywords

BIRCH POLLEN ANTIGEN; ICOS PROTEIN; IMMUNOSUPPRESSIVE AGENT; POLLEN ANTIGEN; PROTEIN; PROTOLLIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG;

EID: 84866170168     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1201194     Document Type: Article
Times cited : (20)

References (66)
  • 1
    • 47949119866 scopus 로고    scopus 로고
    • Pathogenesis of asthma
    • Holgate, S. T. 2008. Pathogenesis of asthma. Clin. Exp. Allergy 38: 872-897.
    • (2008) Clin. Exp. Allergy , vol.38 , pp. 872-897
    • Holgate, S.T.1
  • 3
    • 20444393509 scopus 로고    scopus 로고
    • TLR2 agonist ameliorates established allergic airway inflammation by promoting Th1 response and not via regulatory T cells
    • Patel, M., D. Xu, P. Kewin, B. Choo-Kang, C. McSharry, N. C. Thomson, and F. Y. Liew. 2005. TLR2 agonist ameliorates established allergic airway inflammation by promoting Th1 response and not via regulatory T cells. J. Immunol. 174: 7558-7563. (Pubitemid 40806259)
    • (2005) Journal of Immunology , vol.174 , Issue.12 , pp. 7558-7563
    • Patel, M.1    Xu, D.2    Kewin, P.3    Choo-Kang, B.4    McSharry, C.5    Thomson, N.C.6    Liew, F.Y.7
  • 4
    • 53749099495 scopus 로고    scopus 로고
    • Toll-like receptor 4 agonists adsorbed to aluminium hydroxide adjuvant attenuate ovalbumin-specific allergic airway disease: Role of MyD88 adaptor molecule and interleukin-12/interferon-gamma axis
    • Bortolatto, J., E. Borducchi, D. Rodriguez, A. C. Keller, E. Faquim-Mauro, K. R. Bortoluci, D. Mucida, E. Gomes, A. Christ, S. Schnyder-Candrian, et al. 2008. Toll-like receptor 4 agonists adsorbed to aluminium hydroxide adjuvant attenuate ovalbumin-specific allergic airway disease: role of MyD88 adaptor molecule and interleukin-12/interferon-gamma axis. Clin. Exp. Allergy 38: 1668-1679.
    • (2008) Clin. Exp. Allergy , vol.38 , pp. 1668-1679
    • Bortolatto, J.1    Borducchi, E.2    Rodriguez, D.3    Keller, A.C.4    Faquim-Mauro, E.5    Bortoluci, K.R.6    Mucida, D.7    Gomes, E.8    Christ, A.9    Schnyder-Candrian, S.10
  • 11
    • 4143135369 scopus 로고    scopus 로고
    • Protollin™: A novel adjuvant for intranasal vaccines
    • DOI 10.1016/j.vaccine.2004.03.035, PII S0264410X04002828
    • Jones, T., S. Cyr, F. Allard, N. Bellerose, G. H. Lowell, and D. S. Burt. 2004. Protollin: a novel adjuvant for intranasal vaccines. Vaccine 22: 3691-3697. (Pubitemid 39099644)
    • (2004) Vaccine , vol.22 , Issue.27-28 , pp. 3691-3697
    • Jones, T.1    Cyr, S.2    Allard, F.3    Bellerose, N.4    Lowell, G.H.5    Burt, D.S.6
  • 12
    • 0034967546 scopus 로고    scopus 로고
    • Safety and immunogenicity of a proteosome-Shigella flexneri 2a lipopolysaccharide vaccine administered intranasally to healthy adults
    • DOI 10.1128/IAI.69.7.4545-4553.2001
    • Fries, L. F., A. D. Montemarano, C. P. Mallett, D. N. Taylor, T. L. Hale, and G. H. Lowell. 2001. Safety and immunogenicity of a proteosome-Shigella flexneri 2a lipopolysaccharide vaccine administered intranasally to healthy adults. Infect. Immun. 69: 4545-4553. (Pubitemid 32574456)
    • (2001) Infection and Immunity , vol.69 , Issue.7 , pp. 4545-4553
    • Fries, L.F.1    Montemarano, A.D.2    Mallett, C.P.3    Taylor, D.N.4    Hale, T.L.5    Lowell, G.H.6
  • 13
    • 29044438039 scopus 로고    scopus 로고
    • Intranasal administration of a proteosome-influenza vaccine is well-tolerated and induces serum and nasal secretion influenza antibodies in healthy human subjects
    • DOI 10.1016/j.vaccine.2005.07.088, PII S0264410X05007723
    • Treanor, J., C. Nolan, D. O'Brien, D. Burt, G. Lowell, J. Linden, and L. Fries. 2006. Intranasal administration of a proteosome-influenza vaccine is well-tolerated and induces serum and nasal secretion influenza antibodies in healthy human subjects. Vaccine 24: 254-262. (Pubitemid 41790428)
    • (2006) Vaccine , vol.24 , Issue.3 , pp. 254-262
    • Treanor, J.1    Nolan, C.2    O'Brien, D.3    Burt, D.4    Lowell, G.5    Linden, J.6    Fries, L.7
  • 14
    • 0035850955 scopus 로고    scopus 로고
    • Nasal immunization with subunit proteosome influenza vaccines induces serum HAI, mucosal IgA and protection against influenza challenge
    • DOI 10.1016/S0264-410X(01)00268-7, PII S0264410X01002687
    • Plante, M., T. Jones, F. Allard, K. Torossian, J. Gauthier, N. St-Félix, G. L. White, G. H. Lowell, and D. S. Burt. 2001. Nasal immunization with subunit proteosome influenza vaccines induces serum HAI, mucosal IgA and protection against influenza challenge. Vaccine 20: 218-225. (Pubitemid 32905335)
    • (2001) Vaccine , vol.20 , Issue.1-2 , pp. 218-225
    • Plante, M.1    Jones, T.2    Allard, F.3    Torossian, K.4    Gauthier, J.5    St-Felix, N.6    White, G.L.7    Lowell, G.H.8    Burt, D.S.9
  • 15
    • 33947729215 scopus 로고    scopus 로고
    • C57Bl/6 mice are protected from respiratory syncytial virus (RSV) challenge and IL-5 associated pulmonary eosinophilic infiltrates following intranasal immunization with Protollin-eRSV vaccine
    • DOI 10.1016/j.vaccine.2007.01.037, PII S0264410X07000680
    • Cyr, S. L., T. Jones, I. Stoica-Popescu, D. Burt, and B. J. Ward. 2007. C57Bl/6 mice are protected from respiratory syncytial virus (RSV) challenge and IL-5 associated pulmonary eosinophilic infiltrates following intranasal immunization with Protollin-eRSV vaccine. Vaccine 25: 3228-3232. (Pubitemid 46505048)
    • (2007) Vaccine , vol.25 , Issue.16 SPEC. ISS. , pp. 3228-3232
    • Cyr, S.L.1    Jones, T.2    Stoica-Popescu, I.3    Burt, D.4    Ward, B.J.5
  • 16
    • 34447647449 scopus 로고    scopus 로고
    • Intranasal Protollin-formulated recombinant SARS S-protein elicits respiratory and serum neutralizing antibodies and protection in mice
    • DOI 10.1016/j.vaccine.2007.06.017, PII S0264410X07006950
    • Hu, M. C., T. Jones, R. T. Kenney, D. L. Barnard, D. S. Burt, and G. H. Lowell. 2007. Intranasal Protollin-formulated recombinant SARS S-protein elicits respiratory and serum neutralizing antibodies and protection in mice. Vaccine 25: 6334-6340. (Pubitemid 47088756)
    • (2007) Vaccine , vol.25 , Issue.34 , pp. 6334-6340
    • Hu, M.C.1    Jones, T.2    Kenney, R.T.3    Barnard, D.L.4    Burt, D.S.5    Lowell, G.H.6
  • 17
    • 32544441535 scopus 로고    scopus 로고
    • Intranasal Protollin™/F1-V vaccine elicits respiratory and serum antibody responses and protects mice against lethal aerosolized plague infection
    • DOI 10.1016/j.vaccine.2005.09.052, PII S0264410X05010248
    • Jones, T., J. J. Adamovicz, S. L. Cyr, C. R. Bolt, N. Bellerose, L. M. Pitt, G. H. Lowell, and D. S. Burt. 2006. Intranasal Protollin/F1-V vaccine elicits respiratory and serum antibody responses and protects mice against lethal aerosolized plague infection. Vaccine 24: 1625-1632. (Pubitemid 43238239)
    • (2006) Vaccine , vol.24 , Issue.10 , pp. 1625-1632
    • Jones, T.1    Adamovicz, J.J.2    Cyr, S.L.3    Bolt, C.R.4    Bellerose, N.5    Pitt, L.M.6    Lowell, G.H.7    Burt, D.S.8
  • 18
    • 12344323316 scopus 로고    scopus 로고
    • A novel intranasal Protollin™-based measles vaccine induces mucosal and systemic neutralizing antibody responses and cell-mediated immunity in mice
    • DOI 10.1016/j.vaccine.2004.09.010, PII S0264410X04006838
    • Chabot, S., A. Brewer, G. Lowell, M. Plante, S. Cyr, D. S. Burt, and B. J. Ward. 2005. A novel intranasal Protollin-based measles vaccine induces mucosal and systemic neutralizing antibody responses and cell-mediated immunity in mice. Vaccine 23: 1374-1383. (Pubitemid 40127330)
    • (2005) Vaccine , vol.23 , Issue.11 , pp. 1374-1383
    • Chabot, S.1    Brewer, A.2    Lowell, G.3    Plante, M.4    Cyr, S.5    Burt, D.S.6    Ward, B.J.7
  • 19
    • 24644435506 scopus 로고    scopus 로고
    • Nasal vaccination with a proteosome-based adjuvant and glatiramer acetate clears β-amyloid in a mouse model of Alzheimer disease
    • DOI 10.1172/JCI23241
    • Frenkel, D., R. Maron, D. S. Burt, and H. L. Weiner. 2005. Nasal vaccination with a proteosome-based adjuvant and glatiramer acetate clears beta-amyloid in a mouse model of Alzheimer disease. J. Clin. Invest. 115: 2423-2433. (Pubitemid 41266204)
    • (2005) Journal of Clinical Investigation , vol.115 , Issue.9 , pp. 2423-2433
    • Frenkel, D.1    Maron, R.2    Burt, D.S.3    Weiner, H.L.4
  • 20
    • 34347236488 scopus 로고    scopus 로고
    • TLR2 activation by proteosomes promotes uptake of particulate vaccines at mucosal surfaces
    • DOI 10.1016/j.vaccine.2007.05.029, PII S0264410X07005622
    • Chabot, S. M., T. S. Chernin, M. Shawi, J. Wagner, S. Farrant, D. S. Burt, S. Cyr, and M. R. Neutra. 2007. TLR2 activation by proteosomes promotes uptake of particulate vaccines at mucosal surfaces. Vaccine 25: 5348-5358. (Pubitemid 46992759)
    • (2007) Vaccine , vol.25 , Issue.29 , pp. 5348-5358
    • Chabot, S.M.1    Chernin, T.S.2    Shawi, M.3    Wagner, J.4    Farrant, S.5    Burt, D.S.6    Cyr, S.7    Neutra, M.R.8
  • 21
    • 0037083638 scopus 로고    scopus 로고
    • Cutting edge: Immune stimulation by neisserial porins is toll-like receptor 2 and MyD88 dependent
    • Massari, P., P. Henneke, Y. Ho, E. Latz, D. T. Golenbock, and L. M. Wetzler. 2002. Cutting edge: Immune stimulation by neisserial porins is toll-like receptor 2 and MyD88 dependent. J. Immunol. 168: 1533-1537. (Pubitemid 34135744)
    • (2002) Journal of Immunology , vol.168 , Issue.4 , pp. 1533-1537
    • Massari, P.1    Henneke, P.2    Ho, Y.3    Latz, E.4    Golenbock, D.T.5    Wetzler, L.M.6
  • 23
    • 23344438931 scopus 로고    scopus 로고
    • Bronchus- and nasal-associated lymphoid tissues
    • DOI 10.1111/j.0105-2896.2005.00299.x
    • Bienenstock, J., and M. R. McDermott. 2005. Bronchus- and nasal-associated lymphoid tissues. Immunol. Rev. 206: 22-31. (Pubitemid 41105161)
    • (2005) Immunological Reviews , vol.206 , pp. 22-31
    • Bienenstock, J.1    McDermott, M.R.2
  • 25
    • 78049239398 scopus 로고    scopus 로고
    • Educating CD4 T cells with vaccine adjuvants: Lessons from lipopolysaccharide
    • McAleer, J. P., and A. T. Vella. 2010. Educating CD4 T cells with vaccine adjuvants: lessons from lipopolysaccharide. Trends Immunol. 31: 429-435.
    • (2010) Trends Immunol. , vol.31 , pp. 429-435
    • McAleer, J.P.1    Vella, A.T.2
  • 26
    • 70249131137 scopus 로고    scopus 로고
    • Type I interferon signaling in dendritic cells stimulates the development of lymph-node-resident T follicular helper cells
    • Cucak, H., U. Yrlid, B. Reizis, U. Kalinke, and B. Johansson-Lindbom. 2009. Type I interferon signaling in dendritic cells stimulates the development of lymph-node-resident T follicular helper cells. Immunity 31: 491-501.
    • (2009) Immunity , vol.31 , pp. 491-501
    • Cucak, H.1    Yrlid, U.2    Reizis, B.3    Kalinke, U.4    Johansson-Lindbom, B.5
  • 27
    • 34247554229 scopus 로고    scopus 로고
    • + T cell response
    • den Haan, J. M., G. Kraal, and M. J. Bevan. 2007. Cutting edge: Lipopolysaccharide induces IL-10-producing regulatory CD4+ T cells that suppress the CD8 + T cell response. J. Immunol. 178: 5429-5433. (Pubitemid 46674336)
    • (2007) Journal of Immunology , vol.178 , Issue.9 , pp. 5429-5433
    • Den, H.J.M.M.1    Kraal, G.2    Bevan, M.J.3
  • 28
    • 0037121946 scopus 로고    scopus 로고
    • Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen
    • DOI 10.1084/jem.20021340
    • Eisenbarth, S. C., D. A. Piggott, J. W. Huleatt, I. Visintin, C. A. Herrick, and K. Bottomly. 2002. Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen. J. Exp. Med. 196: 1645-1651. (Pubitemid 36026476)
    • (2002) Journal of Experimental Medicine , vol.196 , Issue.12 , pp. 1645-1651
    • Eisenbarth, S.C.1    Piggott, D.A.2    Huleatt, J.W.3    Visintin, I.4    Herrick, C.A.5    Bottomly, K.6
  • 29
    • 77954688261 scopus 로고    scopus 로고
    • Potent intestinal Th17 priming through peripheral lipopolysaccharide- based immunization
    • McAleer, J. P., B. Liu, Z. Li, S. M. Ngoi, J. Dai, M. Oft, and A. T. Vella. 2010. Potent intestinal Th17 priming through peripheral lipopolysaccharide-based immunization. J. Leukoc. Biol. 88: 21-31.
    • (2010) J. Leukoc. Biol. , vol.88 , pp. 21-31
    • McAleer, J.P.1    Liu, B.2    Li, Z.3    Ngoi, S.M.4    Dai, J.5    Oft, M.6    Vella, A.T.7
  • 31
    • 77949415690 scopus 로고    scopus 로고
    • Immunomodulating effects of endotoxin in mouse models of allergic asthma
    • Zhu, Z., S. Y. Oh, T. Zheng, and Y. K. Kim. 2010. Immunomodulating effects of endotoxin in mouse models of allergic asthma. Clin. Exp. Allergy 40: 536-546.
    • (2010) Clin. Exp. Allergy , vol.40 , pp. 536-546
    • Zhu, Z.1    Oh, S.Y.2    Zheng, T.3    Kim, Y.K.4
  • 34
    • 33745369494 scopus 로고    scopus 로고
    • Neonatal exposure with LPS and/or allergen prevents experimental allergic airways disease: Development of tolerance using environmental antigens
    • DOI 10.1016/j.jaci.2006.03.020, PII S0091674906007251
    • Wang, Y., and C. McCusker. 2006. Neonatal exposure with LPS and/or allergen prevents experimental allergic airways disease: development of tolerance using environmental antigens. J. Allergy Clin. Immunol. 118: 143-151. (Pubitemid 43946471)
    • (2006) Journal of Allergy and Clinical Immunology , vol.118 , Issue.1 , pp. 143-151
    • Wang, Y.1    McCusker, C.2
  • 38
    • 0037371432 scopus 로고    scopus 로고
    • Inducible costimulatory molecule-B7-related protein 1 interactions are important for the clonal expansion and B cell helper functions of naive, Th1, and Th2 T cells
    • Smith, K. M., J. M. Brewer, P. Webb, A. J. Coyle, C. Gutierrez-Ramos, and P. Garside. 2003. Inducible costimulatory molecule-B7-related protein 1 interactions are important for the clonal expansion and B cell helper functions of naive, Th1, and Th2 T cells. J. Immunol. 170: 2310-2315. (Pubitemid 36245616)
    • (2003) Journal of Immunology , vol.170 , Issue.5 , pp. 2310-2315
    • Smith, K.M.1    Brewer, J.M.2    Webb, P.3    Coyle, A.J.4    Gutierrez-Ramos, C.5    Garside, P.6
  • 41
    • 84863131186 scopus 로고    scopus 로고
    • Murine regulatory T cells contain hyperproliferative and death-prone subsets with differential ICOS expression
    • Chen, Y., S. Shen, B. K. Gorentla, J. Gao, and X. P. Zhong. 2012. Murine regulatory T cells contain hyperproliferative and death-prone subsets with differential ICOS expression. J. Immunol. 188: 1698-1707.
    • (2012) J. Immunol. , vol.188 , pp. 1698-1707
    • Chen, Y.1    Shen, S.2    Gorentla, B.K.3    Gao, J.4    Zhong, X.P.5
  • 42
    • 0036907606 scopus 로고    scopus 로고
    • Site-specific sensitization in a murine model of allergic rhinitis: Role of the upper airway in lower airways disease
    • DOI 10.1067/mai.2002.130048
    • McCusker, C., M. Chicoine, Q. Hamid, and B. Mazer. 2002. Site-specific sensitization in a murine model of allergic rhinitis: role of the upper airway in lower airways disease. J. Allergy Clin. Immunol. 110: 891-898. (Pubitemid 36005877)
    • (2002) Journal of Allergy and Clinical Immunology , vol.110 , Issue.6 , pp. 891-898
    • McCusker, C.1    Chicoine, M.2    Hamid, Q.3    Mazer, B.4
  • 43
    • 0034643729 scopus 로고    scopus 로고
    • Relation between house-dust endotoxin exposure, type 1 T-cell development, and allergen sensitisation in infants at high risk of asthma
    • Gereda, J. E., D. Y. Leung, A. Thatayatikom, J. E. Streib, M. R. Price, M. D. Klinnert, and A. H. Liu. 2000. Relation between house-dust endotoxin exposure, type 1 T-cell development, and allergen sensitisation in infants at high risk of asthma. Lancet 355: 1680-1683. (Pubitemid 30248480)
    • (2000) Lancet , vol.355 , Issue.9216 , pp. 1680-1683
    • Gereda, J.E.1    Leung, D.Y.M.2    Thatayatikom, A.3    Streib, J.E.4    Price, M.R.5    Klinnert, M.D.6    Liu, A.H.7
  • 48
    • 0021289324 scopus 로고
    • Biological actitivies of synthetic Lipid A analogs: Pyrogenicity, lethal toxicity, anticomplement activity, and induction of gelation of Limulus amoebocyte lysate
    • Tanamoto, K., U. Zähringer, G. R. McKenzie, C. Galanos, E. T. Rietschel, O. Lüderitz, S. Kusumoto, and T. Shiba. 1984. Biological activities of synthetic lipid A analogs: pyrogenicity, lethal toxicity, anticomplement activity, and induction of gelation of Limulus amoebocyte lysate. Infect. Immun. 44: 421-426. (Pubitemid 14139008)
    • (1984) Infection and Immunity , vol.44 , Issue.2 , pp. 421-426
    • Tanamoto, K.I.1    Zahringer, U.2    McKenzie, G.R.3
  • 50
    • 80051568013 scopus 로고    scopus 로고
    • Potential of nasopharynx-associated lymphoid tissue for vaccine responses in the airways
    • Brandtzaeg, P. 2011. Potential of nasopharynx-associated lymphoid tissue for vaccine responses in the airways. Am. J. Respir. Crit. Care Med. 183: 1595- 1604.
    • (2011) Am. J. Respir. Crit. Care Med. , vol.183 , pp. 1595-1604
    • Brandtzaeg, P.1
  • 52
    • 0033557738 scopus 로고    scopus 로고
    • Intranasally induced immunological tolerance is determined by characteristics of the draining lymph nodes: Studies with OVA and human cartilage gp-39
    • Wolvers, D. A., C. J. Coenen-de Roo, R. E. Mebius, M. J. van der Cammen, F. Tirion, A. M. Miltenburg, and G. Kraal. 1999. Intranasally induced immunological tolerance is determined by characteristics of the draining lymph nodes: studies with OVA and human cartilage gp-39. J. Immunol. 162: 1994-1998. (Pubitemid 29288817)
    • (1999) Journal of Immunology , vol.162 , Issue.4 , pp. 1994-1998
    • Wolvers, D.A.W.1    Coenen-De, R.C.J.J.2    Mebius, R.E.3    Van Der, C.M.J.F.4    Tirion, F.5    Miltenburg, A.M.M.6    Kraal, G.7
  • 53
    • 57749193730 scopus 로고    scopus 로고
    • TLR4 and MyD88 control protection and pulmonary granulocytic recruitment in a murine intranasal RSV immunization and challenge model
    • Cyr, S. L., I. Angers, L. Guillot, I. Stoica-Popescu, M. Lussier, S. Qureshi, D. S. Burt, and B. J. Ward. 2009. TLR4 and MyD88 control protection and pulmonary granulocytic recruitment in a murine intranasal RSV immunization and challenge model. Vaccine 27: 421-430.
    • (2009) Vaccine , vol.27 , pp. 421-430
    • Cyr, S.L.1    Angers, I.2    Guillot, L.3    Stoica-Popescu, I.4    Lussier, M.5    Qureshi, S.6    Burt, D.S.7    Ward, B.J.8
  • 54
    • 78650815222 scopus 로고    scopus 로고
    • Differential effect of TLR2 and TLR4 on the immune response after immunization with a vaccine against Neisseria meningitidis or Bordetella pertussis
    • Fransen, F., R. M. Stenger, M. C. Poelen, H. H. van Dijken, B. Kuipers, C. J. Boog, J. P. van Putten, C. A. van Els, and P. van der Ley. 2010. Differential effect of TLR2 and TLR4 on the immune response after immunization with a vaccine against Neisseria meningitidis or Bordetella pertussis. PLoS ONE 5: e15692.
    • (2010) PLoS ONE , vol.5
    • Fransen, F.1    Stenger, R.M.2    Poelen, M.C.3    Van Dijken, H.H.4    Kuipers, B.5    Boog, C.J.6    Van Putten, J.P.7    Van Els, C.A.8    Van Der Ley, P.9
  • 55
    • 0042029637 scopus 로고    scopus 로고
    • Exposure to endotoxin and allergen in early life and its effect on allergen sensitization in mice
    • DOI 10.1067/mai.2003.1646
    • Gerhold, K., K. Bluemchen, A. Franke, P. Stock, and E. Hamelmann. 2003. Exposure to endotoxin and allergen in early life and its effect on allergen sensitization in mice. J. Allergy Clin. Immunol. 112: 389-396. (Pubitemid 36981381)
    • (2003) Journal of Allergy and Clinical Immunology , vol.112 , Issue.2 , pp. 389-396
    • Gerhold, K.1    Bluemchen, K.2    Franke, A.3    Stock, P.4    Hamelmann, E.5
  • 57
    • 49749084305 scopus 로고    scopus 로고
    • Lipopolysaccharides modulate allergen-specific immune regulation in a murine model of mucosal tolerance induction
    • Gerhold, K., A. Avagyan, E. Reichert, K. Blumchen, U. Wahn, and E. Hamelmann. 2008. Lipopolysaccharides modulate allergen-specific immune regulation in a murine model of mucosal tolerance induction. Int. Arch. Allergy Immunol. 147: 25-34.
    • (2008) Int. Arch. Allergy Immunol. , vol.147 , pp. 25-34
    • Gerhold, K.1    Avagyan, A.2    Reichert, E.3    Blumchen, K.4    Wahn, U.5    Hamelmann, E.6
  • 59
    • 69249083836 scopus 로고    scopus 로고
    • Cutting edge: IL-27 induces the transcription factor c-Maf, cytokine IL-21, and the costimulatory receptor ICOS that coordinately act together to promote differentiation of IL-10-producing Tr1 cells
    • Pot, C., H. Jin, A. Awasthi, S. M. Liu, C. Y. Lai, R. Madan, A. H. Sharpe, C. L. Karp, S. C. Miaw, I. C. Ho, and V. K. Kuchroo. 2009. Cutting edge: IL-27 induces the transcription factor c-Maf, cytokine IL-21, and the costimulatory receptor ICOS that coordinately act together to promote differentiation of IL-10-producing Tr1 cells. J. Immunol. 183: 797-801.
    • (2009) J. Immunol. , vol.183 , pp. 797-801
    • Pot, C.1    Jin, H.2    Awasthi, A.3    Liu, S.M.4    Lai, C.Y.5    Madan, R.6    Sharpe, A.H.7    Karp, C.L.8    Miaw, S.C.9    Ho, I.C.10    Kuchroo, V.K.11
  • 61
    • 65449156015 scopus 로고    scopus 로고
    • The role of ICOS in directing T cell responses: ICOS-dependent induction of T cell anergy by tolerogenic dendritic cells
    • Tuettenberg, A., E. Huter, M. Hubo, J. Horn, J. Knop, B. Grimbacher, R. A. Kroczek, S. Stoll, and H. Jonuleit. 2009. The role of ICOS in directing T cell responses: ICOS-dependent induction of T cell anergy by tolerogenic dendritic cells. J. Immunol. 182: 3349-3356.
    • (2009) J. Immunol. , vol.182 , pp. 3349-3356
    • Tuettenberg, A.1    Huter, E.2    Hubo, M.3    Horn, J.4    Knop, J.5    Grimbacher, B.6    Kroczek, R.A.7    Stoll, S.8    Jonuleit, H.9
  • 62
    • 2142825777 scopus 로고    scopus 로고
    • Human T Cell Activation by Costimulatory Signal-Deficient Allogeneic Cells Induces Inducible Costimulator-Expressing Anergic T Cells with Regulatory Cell Activity
    • Vermeiren, J., J. L. Ceuppens, M. Van Ghelue, P. Witters, D. Bullens, H. W. Mages, R. A. Kroczek, and S.W. Van Gool. 2004. Human T cell activation by costimulatory signal-deficient allogeneic cells induces inducible costimulator-expressing anergic T cells with regulatory cell activity. J. Immunol. 172: 5371-5378. (Pubitemid 38542036)
    • (2004) Journal of Immunology , vol.172 , Issue.9 , pp. 5371-5378
    • Vermeiren, J.1    Ceuppens, J.L.2    Van Ghelue, M.3    Witters, P.4    Bullens, D.5    Mages, H.W.6    Kroczek, R.A.7    Van Gool, S.W.8
  • 63
    • 0036732461 scopus 로고    scopus 로고
    • Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity
    • DOI 10.1038/nm745
    • Akbari, O., G. J. Freeman, E. H. Meyer, E. A. Greenfield, T. T. Chang, A. H. Sharpe, G. Berry, R. H. DeKruyff, and D. T. Umetsu. 2002. Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity. Nat. Med. 8: 1024-1032. (Pubitemid 35033708)
    • (2002) Nature Medicine , vol.8 , Issue.9 , pp. 1024-1032
    • Akbari, O.1    Freeman, G.J.2    Meyer, E.H.3    Greenfield, E.A.4    Chang, T.T.5    Sharpe, A.H.6    Berry, G.7    Dekruyff, R.H.8    Umetsu, D.T.9
  • 64
    • 84455199735 scopus 로고    scopus 로고
    • IL-35 production by inducible costimulator (ICOS)-positive regulatory T cells reverses established IL-17-dependent allergic airways disease
    • Whitehead, G. S., R. H. Wilson, K. Nakano, L. H. Burch, H. Nakano, and D. N. Cook. 2012. IL-35 production by inducible costimulator (ICOS)-positive regulatory T cells reverses established IL-17-dependent allergic airways disease. J. Allergy Clin. Immunol. 129: 207-215, e1-e5.
    • (2012) J. Allergy Clin. Immunol. , vol.129
    • Whitehead, G.S.1    Wilson, R.H.2    Nakano, K.3    Burch, L.H.4    Nakano, H.5    Cook, D.N.6
  • 65
    • 84857364650 scopus 로고    scopus 로고
    • Lipopolysaccharide mediated mast cells induce IL-10 producing regulatory T cells through the ICOSL/ICOS axis
    • Nie, X., G. Cai, W. Zhang, H. Wang, B. Wu, Q. Li, and Q. Shen. 2012. Lipopolysaccharide mediated mast cells induce IL-10 producing regulatory T cells through the ICOSL/ICOS axis. Clin. Immunol. 142: 269-279.
    • (2012) Clin. Immunol. , vol.142 , pp. 269-279
    • Nie, X.1    Cai, G.2    Zhang, W.3    Wang, H.4    Wu, B.5    Li, Q.6    Shen, Q.7
  • 66
    • 20844458651 scopus 로고    scopus 로고
    • Antagonism between MyD88- and TRIF-dependent signals in B7RP-1 up-regulation
    • DOI 10.1002/eji.200525971
    • Zhou, Z., K. Hoebe, X. Du, Z. Jiang, L. Shamel, and B. Beutler. 2005. Antagonism between MyD88- and TRIF-dependent signals in B7RP-1 up-regulation. Eur. J. Immunol. 35: 1918-1927. (Pubitemid 40862340)
    • (2005) European Journal of Immunology , vol.35 , Issue.6 , pp. 1918-1927
    • Zhou, Z.1    Hoebe, K.2    Du, X.3    Jiang, Z.4    Shamel, L.5    Beutler, B.6


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