AIM2 inflammasome is activated by pharmacological disruption of nuclear envelope integrity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 32, 2016, Pages E4671-E4680

  Micco, Antonia Di ^a   Frera, Gianluca ^a   Lugrin, Jérôme ^a   Jamilloux, Yvan ^a,b   Hsu, Erh Ting ^c   Tardivel, Aubry ^a   Gassart, Aude De ^a   Zaffalon, Léa ^a   Bujisic, Bojan ^a   Siegert, Stefanie ^a   Quadroni, Manfredo ^a   Broz, Petr ^d   Henry, Thomas ^b   Hrycyna, Christine A ^c,e   Martinon, Fabio ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b INSERM   (France)

^c PURDUE UNIVERSITY   (United States)

^d UNIVERSITY OF BASEL   (Switzerland)

^e Purdue University   (United States)

Author keywords

DNA sensors zmpste24; Inflammasome nuclear envelope stress; Nelfinavir

Indexed keywords

INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; LAMIN A; NELFINAVIR; CASPASE RECRUITMENT DOMAIN SIGNALING PROTEIN; CRYOPYRIN; DNA; INTERLEUKIN 1 RECEPTOR; NLRP3 PROTEIN, MOUSE; PYCARD PROTEIN, MOUSE;

ANIMAL CELL; CELL NUCLEUS MEMBRANE; CONFERENCE PAPER; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MOLECULAR SENSOR; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN SECRETION; ANIMAL; C57BL MOUSE; DRUG EFFECTS; METABOLISM; MOUSE; PHYSIOLOGY; SECRETION (PROCESS);

ANIMALS; CARD SIGNALING ADAPTOR PROTEINS; CASPASE 1; DNA; INFLAMMASOMES; INTERLEUKIN-1BETA; MICE; MICE, INBRED C57BL; NELFINAVIR; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; NUCLEAR ENVELOPE; RECEPTORS, INTERLEUKIN-1;

EID: 84982972146     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1602419113     Document Type: Article

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