-
1
-
-
85035392112
-
Liver fibrosis
-
PMID: 15690074
-
Bataller R, Brenner DA. Liver fibrosis. J Clin Invest 2005; 115: 209-218 [PMID: 15690074 DOI: 10.1172/JCI24282]
-
(2005)
J Clin Invest
, vol.115
, pp. 209-218
-
-
Bataller, R.1
Brenner, D.A.2
-
2
-
-
0036637294
-
Liver regeneration
-
PMID: 12086922
-
Diehl AM. Liver regeneration. Front Biosci 2002; 7: e301-e314 [PMID: 12086922 DOI: 10.2741/diehl]
-
(2002)
Front Biosci
, vol.7
, pp. e301-e314
-
-
Diehl, A.M.1
-
3
-
-
2542601615
-
Liver regeneration and repair: Hepatocytes, progenitor cells, and stem cells
-
PMID: 15185286
-
Fausto N. Liver regeneration and repair: hepatocytes, progenitor cells, and stem cells. Hepatology 2004; 39: 1477-1487 [PMID: 15185286 DOI: 10.1002/hep.20214]
-
(2004)
Hepatology
, vol.39
, pp. 1477-1487
-
-
Fausto, N.1
-
4
-
-
5044232017
-
Liver regeneration: From myth to mechanism
-
PMID: 15459664
-
Taub R. Liver regeneration: from myth to mechanism. Nat Rev Mol Cell Biol 2004; 5: 836-847 [PMID: 15459664 DOI: 10.1038/nrm1489]
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, pp. 836-847
-
-
Taub, R.1
-
5
-
-
0037213389
-
The role of hepatocytes and oval cells in liver regeneration and repopulation
-
PMID: 12490302
-
Fausto N, Campbell JS. The role of hepatocytes and oval cells in liver regeneration and repopulation. Mech Dev 2003; 120: 117-130 [PMID: 12490302 DOI: 10.1016/S0925-4773(02)00338-6]
-
(2003)
Mech Dev
, vol.120
, pp. 117-130
-
-
Fausto, N.1
Campbell, J.S.2
-
6
-
-
84879808762
-
Overexpression of c-myc in hepatocytes promotes activation of hepatic stellate cells and facilitates the onset of liver fibrosis
-
PMID: 23770341
-
Nevzorova YA, Hu W, Cubero FJ, Haas U, Freimuth J, Tacke F, Trautwein C, Liedtke C. Overexpression of c-myc in hepatocytes promotes activation of hepatic stellate cells and facilitates the onset of liver fibrosis. Biochim Biophys Acta 2013; 1832: 1765-1775 [PMID: 23770341 DOI: 10.1016/j.bbadis.2013.06.001]
-
(2013)
Biochim Biophys Acta
, vol.1832
, pp. 1765-1775
-
-
Nevzorova, Y.A.1
Hu, W.2
Cubero, F.J.3
Haas, U.4
Freimuth, J.5
Tacke, F.6
Trautwein, C.7
Liedtke, C.8
-
7
-
-
1242291937
-
Oval cells compensate for damage and replicative senescence of mature hepatocytes in mice with fatty liver disease
-
PMID: 14767993
-
Yang S, Koteish A, Lin H, Huang J, Roskams T, Dawson V, Diehl AM. Oval cells compensate for damage and replicative senescence of mature hepatocytes in mice with fatty liver disease. Hepatology 2004; 39: 403-411 [PMID: 14767993 DOI: 10.1002/hep.20082]
-
(2004)
Hepatology
, vol.39
, pp. 403-411
-
-
Yang, S.1
Koteish, A.2
Lin, H.3
Huang, J.4
Roskams, T.5
Dawson, V.6
Diehl, A.M.7
-
8
-
-
84863527283
-
Activated hepatic stellate cells: Negative regulators of hepatocyte proliferation in liver diseases
-
PMID: 22876366
-
Chung C, Iwakiri Y. Activated hepatic stellate cells: negative regulators of hepatocyte proliferation in liver diseases. Hepatology 2012; 56: 389-391 [PMID: 22876366 DOI: 10.1002/hep.25761]
-
(2012)
Hepatology
, vol.56
, pp. 389-391
-
-
Chung, C.1
Iwakiri, Y.2
-
9
-
-
0034809804
-
Hepatic stellate cells as a target for the treatment of liver fibrosis
-
PMID: 11586471
-
Bataller R, Brenner DA. Hepatic stellate cells as a target for the treatment of liver fibrosis. Semin Liver Dis 2001; 21: 437-451 [PMID: 11586471 DOI: 10.1055/s-2001-17558]
-
(2001)
Semin Liver Dis
, vol.21
, pp. 437-451
-
-
Bataller, R.1
Brenner, D.A.2
-
10
-
-
35948964347
-
Hepatic stellate cells and liver fibrosis
-
PMID: 17979495
-
Moreira RK. Hepatic stellate cells and liver fibrosis. Arch Pathol Lab Med 2007; 131: 1728-1734 [PMID: 17979495]
-
(2007)
Arch Pathol Lab Med
, vol.131
, pp. 1728-1734
-
-
Moreira, R.K.1
-
11
-
-
84877139427
-
Hepatic stellate cells in liver development, regeneration, and cancer
-
PMID: 23635788
-
Yin C, Evason KJ, Asahina K, Stainier DY. Hepatic stellate cells in liver development, regeneration, and cancer. J Clin Invest 2013; 123: 1902-1910 [PMID: 23635788 DOI: 10.1172/JCI66369]
-
(2013)
J Clin Invest
, vol.123
, pp. 1902-1910
-
-
Yin, C.1
Evason, K.J.2
Asahina, K.3
Stainier, D.Y.4
-
12
-
-
77950323927
-
Pathogenesis of non-alcoholic fatty liver disease
-
PMID: 19914930
-
Dowman JK, Tomlinson JW, Newsome PN. Pathogenesis of non-alcoholic fatty liver disease. QJM 2010; 103: 71-83 [PMID: 19914930 DOI: 10.1093/qjmed/hcp158]
-
(2010)
QJM
, vol.103
, pp. 71-83
-
-
Dowman, J.K.1
Tomlinson, J.W.2
Newsome, P.N.3
-
13
-
-
0035577854
-
Hedgehog signaling in animal development: Paradigms and principles
-
PMID: 11731473
-
Ingham PW, McMahon AP. Hedgehog signaling in animal development: paradigms and principles. Genes Dev 2001; 15: 3059-3087 [PMID: 11731473 DOI: 10.1101/gad.938601]
-
(2001)
Genes Dev
, vol.15
, pp. 3059-3087
-
-
Ingham, P.W.1
McMahon, A.P.2
-
14
-
-
78751585439
-
Hedgehog signaling in the liver
-
PMID: 21093090
-
Omenetti A, Choi S, Michelotti G, Diehl AM. Hedgehog signaling in the liver. J Hepatol 2011; 54: 366-373 [PMID: 21093090 DOI: 10.1016/j.jhep.2010.10.003]
-
(2011)
J Hepatol
, vol.54
, pp. 366-373
-
-
Omenetti, A.1
Choi, S.2
Michelotti, G.3
Diehl, A.M.4
-
15
-
-
78651426961
-
The role of Hedgehog signaling in fibrogenic liver repair
-
PMID: 21056686
-
Choi SS, Omenetti A, Syn WK, Diehl AM. The role of Hedgehog signaling in fibrogenic liver repair. Int J Biochem Cell Biol 2011; 43: 238-244 [PMID: 21056686 DOI: 10.1016/j.biocel.2010.10.015]
-
(2011)
Int J Biochem Cell Biol
, vol.43
, pp. 238-244
-
-
Choi, S.S.1
Omenetti, A.2
Syn, W.K.3
Diehl, A.M.4
-
16
-
-
84868102616
-
Hedgehog controls hepatic stellate cell fate by regulating metabolism
-
e1-11, PMID: 22885334
-
Chen Y, Choi SS, Michelotti GA, Chan IS, Swiderska-Syn M, Karaca GF, Xie G, Moylan CA, Garibaldi F, Premont R, Suliman HB, Piantadosi CA, Diehl AM. Hedgehog controls hepatic stellate cell fate by regulating metabolism. Gastroenterology 2012; 143: 1319-29.e1-11 [PMID: 22885334 DOI: 10.1053/j.gastro.2012.07.115]
-
(2012)
Gastroenterology
, vol.143
, pp. 1319-1329
-
-
Chen, Y.1
Choi, S.S.2
Michelotti, G.A.3
Chan, I.S.4
Swiderska-Syn, M.5
Karaca, G.F.6
Xie, G.7
Moylan, C.A.8
Garibaldi, F.9
Premont, R.10
Suliman, H.B.11
Piantadosi, C.A.12
Diehl, A.M.13
-
17
-
-
36549011761
-
Sonic hedgehog is an autocrine viability factor for myofibroblastic hepatic stellate cells
-
PMID: 18022723
-
Yang L, Wang Y, Mao H, Fleig S, Omenetti A, Brown KD, Sicklick JK, Li YX, Diehl AM. Sonic hedgehog is an autocrine viability factor for myofibroblastic hepatic stellate cells. J Hepatol 2008; 48: 98-106 [PMID: 18022723 DOI: 10.1016/j.jhep.2007.07.032]
-
(2008)
J Hepatol
, vol.48
, pp. 98-106
-
-
Yang, L.1
Wang, Y.2
Mao, H.3
Fleig, S.4
Omenetti, A.5
Brown, K.D.6
Sicklick, J.K.7
Li, Y.X.8
Diehl, A.M.9
-
18
-
-
27144554034
-
Role for hedgehog signaling in hepatic stellate cell activation and viability
-
PMID: 16170335
-
Sicklick JK, Li YX, Choi SS, Qi Y, Chen W, Bustamante M, Huang J, Zdanowicz M, Camp T, Torbenson MS, Rojkind M, Diehl AM. Role for hedgehog signaling in hepatic stellate cell activation and viability. Lab Invest 2005; 85: 1368-1380 [PMID: 16170335 DOI: 10.1038/labinvest.3700349]
-
(2005)
Lab Invest
, vol.85
, pp. 1368-1380
-
-
Sicklick, J.K.1
Li, Y.X.2
Choi, S.S.3
Qi, Y.4
Chen, W.5
Bustamante, M.6
Huang, J.7
Zdanowicz, M.8
Camp, T.9
Torbenson, M.S.10
Rojkind, M.11
Diehl, A.M.12
-
19
-
-
79960935826
-
Hedgehog fights back: Mechanisms of acquired resistance against Smoothened antagonists
-
PMID: 21771911
-
Metcalfe C, de Sauvage FJ. Hedgehog fights back: mechanisms of acquired resistance against Smoothened antagonists. Cancer Res 2011; 71: 5057-5061 [PMID: 21771911 DOI: 10.1158/0008-5472. CAN-11-0923]
-
(2011)
Cancer Res
, vol.71
, pp. 5057-5061
-
-
Metcalfe, C.1
De Sauvage, F.J.2
-
20
-
-
77950858208
-
Hedgehog antagonist cyclopamine isomerizes to less potent forms when acidified
-
PMID: 20236786
-
Wilson SR, Strand MF, Krapp A, Rise F, Petersen D, Krauss S. Hedgehog antagonist cyclopamine isomerizes to less potent forms when acidified. J Pharm Biomed Anal 2010; 52: 707-713 [PMID: 20236786 DOI: 10.1016/j.jpba.2010.02.017]
-
(2010)
J Pharm Biomed Anal
, vol.52
, pp. 707-713
-
-
Wilson, S.R.1
Strand, M.F.2
Krapp, A.3
Rise, F.4
Petersen, D.5
Krauss, S.6
-
21
-
-
18344369543
-
MicroRNA biogenesis: Coordinated cropping and dicing
-
PMID: 15852042
-
Kim VN. MicroRNA biogenesis: coordinated cropping and dicing. Nat Rev Mol Cell Biol 2005; 6: 376-385 [PMID: 15852042 DOI: 10.1038/nrm1644]
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 376-385
-
-
Kim, V.N.1
-
22
-
-
0141843656
-
The nuclear RNase III Drosha initiates microRNA processing
-
PMID: 14508493
-
Lee Y, Ahn C, Han J, Choi H, Kim J, Yim J, Lee J, Provost P, Rådmark O, Kim S, Kim VN. The nuclear RNase III Drosha initiates microRNA processing. Nature 2003; 425: 415-419 [PMID: 14508493 DOI: 10.1038/nature01957]
-
(2003)
Nature
, vol.425
, pp. 415-419
-
-
Lee, Y.1
Ahn, C.2
Han, J.3
Choi, H.4
Kim, J.5
Yim, J.6
Lee, J.7
Provost, P.8
Rådmark, O.9
Kim, S.10
Kim, V.N.11
-
23
-
-
84904985459
-
Regulation of microRNA biogenesis
-
PMID: 25027649
-
Ha M, Kim VN. Regulation of microRNA biogenesis. Nat Rev Mol Cell Biol 2014; 15: 509-524 [PMID: 25027649 DOI: 10.1038/nrm3838]
-
(2014)
Nat Rev Mol Cell Biol
, vol.15
, pp. 509-524
-
-
Ha, M.1
Kim, V.N.2
-
24
-
-
78751477191
-
Gene silencing by microRNAs: Contributions of translational repression and mRNA decay
-
PMID: 21245828
-
Huntzinger E, Izaurralde E. Gene silencing by microRNAs: contributions of translational repression and mRNA decay. Nat Rev Genet 2011; 12: 99-110 [PMID: 21245828 DOI: 10.1038/nrg2936]
-
(2011)
Nat Rev Genet
, vol.12
, pp. 99-110
-
-
Huntzinger, E.1
Izaurralde, E.2
-
25
-
-
58249088751
-
MicroRNAs: Target recognition and regulatory functions
-
PMID: 19167326
-
Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell 2009; 136: 215-233 [PMID: 19167326 DOI: 10.1016/j.cell.2009.01.002]
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
26
-
-
84857968441
-
The majority of microRNAs detectable in serum and saliva is concentrated in exosomes
-
PMID: 22427800
-
Gallo A, Tandon M, Alevizos I, Illei GG. The majority of microRNAs detectable in serum and saliva is concentrated in exosomes. PLoS One 2012; 7: e30679 [PMID: 22427800 DOI: 10.1371/journal.pone.0030679]
-
(2012)
PLoS One
, vol.7
, pp. e30679
-
-
Gallo, A.1
Tandon, M.2
Alevizos, I.3
Illei, G.G.4
-
27
-
-
84894606695
-
MiRNA in plasma exosome is stable under different storage conditions
-
PMID: 24473213
-
Ge Q, Zhou Y, Lu J, Bai Y, Xie X, Lu Z. miRNA in plasma exosome is stable under different storage conditions. Molecules 2014; 19: 1568-1575 [PMID: 24473213 DOI: 10.3390/molecules19021568]
-
(2014)
Molecules
, vol.19
, pp. 1568-1575
-
-
Ge, Q.1
Zhou, Y.2
Lu, J.3
Bai, Y.4
Xie, X.5
Lu, Z.6
-
28
-
-
84946556368
-
MiR-146a-5p suppresses activation and proliferation of hepatic stellate cells in nonalcoholic fibrosing steatohepatitis through directly targeting Wnt1 and Wnt5a
-
PMID: 26537990
-
Du J, Niu X, Wang Y, Kong L, Wang R, Zhang Y, Zhao S, Nan Y. MiR-146a-5p suppresses activation and proliferation of hepatic stellate cells in nonalcoholic fibrosing steatohepatitis through directly targeting Wnt1 and Wnt5a. Sci Rep 2015; 5: 16163 [PMID: 26537990 DOI: 10.1038/srep16163]
-
(2015)
Sci Rep
, vol.5
, pp. 16163
-
-
Du, J.1
Niu, X.2
Wang, Y.3
Kong, L.4
Wang, R.5
Zhang, Y.6
Zhao, S.7
Nan, Y.8
-
29
-
-
0019133661
-
Mutations affecting segment number and polarity in Drosophila
-
PMID: 6776413 DOI: 10.1038/287795a0
-
Nüsslein-Volhard C, Wieschaus E. Mutations affecting segment number and polarity in Drosophila. Nature 1980; 287: 795-801 [PMID: 6776413 DOI: 10.1038/287795a0]
-
(1980)
Nature
, vol.287
, pp. 795-801
-
-
Nüsslein-Volhard, C.1
Wieschaus, E.2
-
30
-
-
33645823699
-
Hedgehog signaling maintains resident hepatic progenitors throughout life
-
PMID: 16322088
-
Sicklick JK, Li YX, Melhem A, Schmelzer E, Zdanowicz M, Huang J, Caballero M, Fair JH, Ludlow JW, McClelland RE, Reid LM, Diehl AM. Hedgehog signaling maintains resident hepatic progenitors throughout life. Am J Physiol Gastrointest Liver Physiol 2006; 290: G859-G870 [PMID: 16322088 DOI: 10.1152/ajpgi.00456.2005]
-
(2006)
Am J Physiol Gastrointest Liver Physiol
, vol.290
, pp. G859-G870
-
-
Sicklick, J.K.1
Li, Y.X.2
Melhem, A.3
Schmelzer, E.4
Zdanowicz, M.5
Huang, J.6
Caballero, M.7
Fair, J.H.8
Ludlow, J.W.9
McClelland, R.E.10
Reid, L.M.11
Diehl, A.M.12
-
31
-
-
67651048548
-
Hedgehog signal activation coordinates proliferation and differentiation of fetal liver progenitor cells
-
PMID: 19559697
-
Hirose Y, Itoh T, Miyajima A. Hedgehog signal activation coordinates proliferation and differentiation of fetal liver progenitor cells. Exp Cell Res 2009; 315: 2648-2657 [PMID: 19559697 DOI: 10.1016/j.yexcr.2009.06.018]
-
(2009)
Exp Cell Res
, vol.315
, pp. 2648-2657
-
-
Hirose, Y.1
Itoh, T.2
Miyajima, A.3
-
32
-
-
9244221172
-
Tissue repair and stem cell renewal in carcinogenesis
-
PMID: 15549094
-
Beachy PA, Karhadkar SS, Berman DM. Tissue repair and stem cell renewal in carcinogenesis. Nature 2004; 432: 324-331 [PMID: 15549094 DOI: 10.1038/nature03100]
-
(2004)
Nature
, vol.432
, pp. 324-331
-
-
Beachy, P.A.1
Karhadkar, S.S.2
Berman, D.M.3
-
33
-
-
0024468746
-
The Drosophila patched gene encodes a putative membrane protein required for segmental patterning
-
PMID: 2582494
-
Hooper JE, Scott MP. The Drosophila patched gene encodes a putative membrane protein required for segmental patterning. Cell 1989; 59: 751-765 [PMID: 2582494 DOI: 10.1016/0092-8674(89)9 0021-4]
-
(1989)
Cell
, vol.59
, pp. 751-765
-
-
Hooper, J.E.1
Scott, M.P.2
-
34
-
-
0024440611
-
A protein with several possible membrane-spanning domains encoded by the Drosophila segment polarity gene patched
-
PMID: 2797178 DOI: 10.1038/341508a0
-
Nakano Y, Guerrero I, Hidalgo A, Taylor A, Whittle JR, Ingham PW. A protein with several possible membrane-spanning domains encoded by the Drosophila segment polarity gene patched. Nature 1989; 341: 508-513 [PMID: 2797178 DOI: 10.1038/341508a0]
-
(1989)
Nature
, vol.341
, pp. 508-513
-
-
Nakano, Y.1
Guerrero, I.2
Hidalgo, A.3
Taylor, A.4
Whittle, J.R.5
Ingham, P.W.6
-
35
-
-
0034682719
-
Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened
-
PMID: 10966113
-
Denef N, Neubüser D, Perez L, Cohen SM. Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened. Cell 2000; 102: 521-531 [PMID: 10966113 DOI: 10.1016/S0092-8674(00)00056-8]
-
(2000)
Cell
, vol.102
, pp. 521-531
-
-
Denef, N.1
Neubüser, D.2
Perez, L.3
Cohen, S.M.4
-
36
-
-
84863012620
-
USP8 promotes smoothened signaling by preventing its ubiquitination and changing its subcellular localization
-
PMID: 22253573
-
Xia R, Jia H, Fan J, Liu Y, Jia J. USP8 promotes smoothened signaling by preventing its ubiquitination and changing its subcellular localization. PLoS Biol 2012; 10: e1001238 [PMID: 22253573 DOI: 10.1371/journal.pbio.1001238]
-
(2012)
PLoS Biol
, vol.10
, pp. e1001238
-
-
Xia, R.1
Jia, H.2
Fan, J.3
Liu, Y.4
Jia, J.5
-
37
-
-
84856366992
-
MiR-25 targets TNF-related apoptosis inducing ligand (TRAIL) death receptor-4 and promotes apoptosis resistance in cholangiocarcinoma
-
PMID: 21953056
-
Razumilava N, Bronk SF, Smoot RL, Fingas CD, Werneburg NW, Roberts LR, Mott JL. miR-25 targets TNF-related apoptosis inducing ligand (TRAIL) death receptor-4 and promotes apoptosis resistance in cholangiocarcinoma. Hepatology 2012; 55: 465-475 [PMID: 21953056 DOI: 10.1002/hep.24698]
-
(2012)
Hepatology
, vol.55
, pp. 465-475
-
-
Razumilava, N.1
Bronk, S.F.2
Smoot, R.L.3
Fingas, C.D.4
Werneburg, N.W.5
Roberts, L.R.6
Mott, J.L.7
-
38
-
-
36049033946
-
Hedgehog regulates smoothened activity by inducing a conformational switch
-
PMID: 17960137
-
Zhao Y, Tong C, Jiang J. Hedgehog regulates smoothened activity by inducing a conformational switch. Nature 2007; 450: 252-258 [PMID: 17960137 DOI: 10.1038/nature06225]
-
(2007)
Nature
, vol.450
, pp. 252-258
-
-
Zhao, Y.1
Tong, C.2
Jiang, J.3
-
39
-
-
0032848136
-
Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: Implication of Gli2 and Gli3 as primary mediators of Shh signaling
-
PMID: 10433919
-
Sasaki H, Nishizaki Y, Hui C, Nakafuku M, Kondoh H. Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling. Development 1999; 126: 3915-3924 [PMID: 10433919]
-
(1999)
Development
, vol.126
, pp. 3915-3924
-
-
Sasaki, H.1
Nishizaki, Y.2
Hui, C.3
Nakafuku, M.4
Kondoh, H.5
-
40
-
-
33244463281
-
GLI3-dependent transcriptional repression of Gli1, Gli2 and kidney patterning genes disrupts renal morphogenesis
-
PMID: 16396903
-
Hu MC, Mo R, Bhella S, Wilson CW, Chuang PT, Hui CC, Rosenblum ND. GLI3-dependent transcriptional repression of Gli1, Gli2 and kidney patterning genes disrupts renal morphogenesis. Development 2006; 133: 569-578 [PMID: 16396903 DOI: 10.1242/dev.02220]
-
(2006)
Development
, vol.133
, pp. 569-578
-
-
Hu, M.C.1
Mo, R.2
Bhella, S.3
Wilson, C.W.4
Chuang, P.T.5
Hui, C.C.6
Rosenblum, N.D.7
-
41
-
-
0034681266
-
Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb
-
PMID: 10693759
-
Wang B, Fallon JF, Beachy PA. Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb. Cell 2000; 100: 423-434 [PMID: 10693759 DOI: 10.1016/S0092-8674(00)80678-9]
-
(2000)
Cell
, vol.100
, pp. 423-434
-
-
Wang, B.1
Fallon, J.F.2
Beachy, P.A.3
-
42
-
-
84879414522
-
The mechanisms of Hedgehog signalling and its roles in development and disease
-
PMID: 23719536
-
Briscoe J, Thérond PP. The mechanisms of Hedgehog signalling and its roles in development and disease. Nat Rev Mol Cell Biol 2013; 14: 416-429 [PMID: 23719536 DOI: 10.1038/nrm3598]
-
(2013)
Nat Rev Mol Cell Biol
, vol.14
, pp. 416-429
-
-
Briscoe, J.1
Thérond, P.P.2
-
43
-
-
0033194243
-
Mammalian suppressorof-fused modulates nuclear-cytoplasmic shuttling of Gli-1
-
PMID: 10559945
-
Kogerman P, Grimm T, Kogerman L, Krause D, Undén AB, Sandstedt B, Toftgård R, Zaphiropoulos PG. Mammalian suppressorof-fused modulates nuclear-cytoplasmic shuttling of Gli-1. Nat Cell Biol 1999; 1: 312-319 [PMID: 10559945 DOI: 10.1038/13031]
-
(1999)
Nat Cell Biol
, vol.1
, pp. 312-319
-
-
Kogerman, P.1
Grimm, T.2
Kogerman, L.3
Krause, D.4
Undén, A.B.5
Sandstedt, B.6
Toftgård, R.7
Zaphiropoulos, P.G.8
-
44
-
-
0033566844
-
Vertebrate homologs of Drosophila suppressor of fused interact with the gli family of transcriptional regulators
-
PMID: 10433824
-
Pearse RV, Collier LS, Scott MP, Tabin CJ. Vertebrate homologs of Drosophila suppressor of fused interact with the gli family of transcriptional regulators. Dev Biol 1999; 212: 323-336 [PMID: 10433824 DOI: 10.1006/dbio.1999.9335]
-
(1999)
Dev Biol
, vol.212
, pp. 323-336
-
-
Pearse, R.V.1
Collier, L.S.2
Scott, M.P.3
Tabin, C.J.4
-
45
-
-
0033491071
-
Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli
-
PMID: 10564661
-
Stone DM, Murone M, Luoh S, Ye W, Armanini MP, Gurney A, Phillips H, Brush J, Goddard A, de Sauvage FJ, Rosenthal A. Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli. J Cell Sci 1999; 112 (Pt 23): 4437-4448 [PMID: 10564661]
-
(1999)
J Cell Sci
, vol.112
, pp. 4437-4448
-
-
Stone, D.M.1
Murone, M.2
Luoh, S.3
Ye, W.4
Armanini, M.P.5
Gurney, A.6
Phillips, H.7
Brush, J.8
Goddard, A.9
De Sauvage, F.J.10
Rosenthal, A.11
-
46
-
-
0038813753
-
Characterization of the physical interaction of Gli proteins with SUFU proteins
-
PMID: 12426310
-
Dunaeva M, Michelson P, Kogerman P, Toftgard R. Characterization of the physical interaction of Gli proteins with SUFU proteins. J Biol Chem 2003; 278: 5116-5122 [PMID: 12426310 DOI: 10.1074/jbc. M209492200]
-
(2003)
J Biol Chem
, vol.278
, pp. 5116-5122
-
-
Dunaeva, M.1
Michelson, P.2
Kogerman, P.3
Toftgard, R.4
-
47
-
-
4544353067
-
Suppressor of fused regulates Gli activity through a dual binding mechanism
-
PMID: 15367681
-
Merchant M, Vajdos FF, Ultsch M, Maun HR, Wendt U, Cannon J, Desmarais W, Lazarus RA, de Vos AM, de Sauvage FJ. Suppressor of fused regulates Gli activity through a dual binding mechanism. Mol Cell Biol 2004; 24: 8627-8641 [PMID: 15367681 DOI: 10.1128/MCB.24.19.8627-8641.2004]
-
(2004)
Mol Cell Biol
, vol.24
, pp. 8627-8641
-
-
Merchant, M.1
Vajdos, F.F.2
Ultsch, M.3
Maun, H.R.4
Wendt, U.5
Cannon, J.6
Desmarais, W.7
Lazarus, R.A.8
De Vos, A.M.9
De Sauvage, F.J.10
-
48
-
-
11144327100
-
Zebrafish Gli3 functions as both an activator and a repressor in Hedgehog signaling
-
PMID: 15617692
-
Tyurina OV, Guner B, Popova E, Feng J, Schier AF, Kohtz JD, Karlstrom RO. Zebrafish Gli3 functions as both an activator and a repressor in Hedgehog signaling. Dev Biol 2005; 277: 537-556 [PMID: 15617692 DOI: 10.1016/j.ydbio.2004.10.003]
-
(2005)
Dev Biol
, vol.277
, pp. 537-556
-
-
Tyurina, O.V.1
Guner, B.2
Popova, E.3
Feng, J.4
Schier, A.F.5
Kohtz, J.D.6
Karlstrom, R.O.7
-
49
-
-
84874453448
-
Hedgehog Gli3 activator signal augments tumorigenicity of colorectal cancer via upregulation of adherencerelated genes
-
PMID: 23176625
-
Iwasaki H, Nakano K, Shinkai K, Kunisawa Y, Hirahashi M, Oda Y, Onishi H, Katano M. Hedgehog Gli3 activator signal augments tumorigenicity of colorectal cancer via upregulation of adherencerelated genes. Cancer Sci 2013; 104: 328-336 [PMID: 23176625 DOI: 10.1111/cas.12073]
-
(2013)
Cancer Sci
, vol.104
, pp. 328-336
-
-
Iwasaki, H.1
Nakano, K.2
Shinkai, K.3
Kunisawa, Y.4
Hirahashi, M.5
Oda, Y.6
Onishi, H.7
Katano, M.8
-
50
-
-
84961657949
-
MicroRNA-378 limits activation of hepatic stellate cells and liver fibrosis by suppressing Gli3 expression
-
PMID: 27001906
-
Hyun J, Wang S, Kim J, Rao KM, Park SY, Chung I, Ha CS, Kim SW, Yun YH, Jung Y. MicroRNA-378 limits activation of hepatic stellate cells and liver fibrosis by suppressing Gli3 expression. Nat Commun 2016; 7: 10993 [PMID: 27001906 DOI: 10.1038/ncomms10993]
-
(2016)
Nat Commun
, vol.7
, pp. 10993
-
-
Hyun, J.1
Wang, S.2
Kim, J.3
Rao, K.M.4
Park, S.Y.5
Chung, I.6
Ha, C.S.7
Kim, S.W.8
Yun, Y.H.9
Jung, Y.10
-
51
-
-
84890567500
-
The intrahepatic signalling niche of hedgehog is defined by primary cilia positive cells during chronic liver injury
-
PMID: 23978713
-
Grzelak CA, Martelotto LG, Sigglekow ND, Patkunanathan B, Ajami K, Calabro SR, Dwyer BJ, Tirnitz-Parker JE, Watkins DN, Warner FJ, Shackel NA, McCaughan GW. The intrahepatic signalling niche of hedgehog is defined by primary cilia positive cells during chronic liver injury. J Hepatol 2014; 60: 143-151 [PMID: 23978713 DOI: 10.1016/j.jhep.2013.08.012]
-
(2014)
J Hepatol
, vol.60
, pp. 143-151
-
-
Grzelak, C.A.1
Martelotto, L.G.2
Sigglekow, N.D.3
Patkunanathan, B.4
Ajami, K.5
Calabro, S.R.6
Dwyer, B.J.7
Tirnitz-Parker, J.E.8
Watkins, D.N.9
Warner, F.J.10
Shackel, N.A.11
McCaughan, G.W.12
-
52
-
-
26644460824
-
Vertebrate Smoothened functions at the primary cilium
-
PMID: 16136078
-
Corbit KC, Aanstad P, Singla V, Norman AR, Stainier DY, Reiter JF. Vertebrate Smoothened functions at the primary cilium. Nature 2005; 437: 1018-1021 [PMID: 16136078 DOI: 10.1038/nature04117]
-
(2005)
Nature
, vol.437
, pp. 1018-1021
-
-
Corbit, K.C.1
Aanstad, P.2
Singla, V.3
Norman, A.R.4
Stainier, D.Y.5
Reiter, J.F.6
-
53
-
-
34547110771
-
Patched1 regulates hedgehog signaling at the primary cilium
-
PMID: 17641202
-
Rohatgi R, Milenkovic L, Scott MP. Patched1 regulates hedgehog signaling at the primary cilium. Science 2007; 317: 372-376 [PMID: 17641202 DOI: 10.1126/science.1139740]
-
(2007)
Science
, vol.317
, pp. 372-376
-
-
Rohatgi, R.1
Milenkovic, L.2
Scott, M.P.3
-
54
-
-
58749105340
-
Modeling ciliopathies: Primary cilia in development and disease
-
PMID: 19186246
-
Quinlan RJ, Tobin JL, Beales PL. Modeling ciliopathies: Primary cilia in development and disease. Curr Top Dev Biol 2008; 84: 249-310 [PMID: 19186246 DOI: 10.1016/S0070-2153(08)00605-4]
-
(2008)
Curr Top Dev Biol
, vol.84
, pp. 249-310
-
-
Quinlan, R.J.1
Tobin, J.L.2
Beales, P.L.3
-
55
-
-
40749144679
-
Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function
-
PMID: 16254602
-
Haycraft CJ, Banizs B, Aydin-Son Y, Zhang Q, Michaud EJ, Yoder BK. Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function. PLoS Genet 2005; 1: e53 [PMID: 16254602 DOI: 10.1371/journal. pgen.0010053]
-
(2005)
PLoS Genet
, vol.1
, pp. e53
-
-
Haycraft, C.J.1
Banizs, B.2
Aydin-Son, Y.3
Zhang, Q.4
Michaud, E.J.5
Yoder, B.K.6
-
56
-
-
77951722845
-
Signals from dying hepatocytes trigger growth of liver progenitors
-
PMID: 20427400
-
Jung Y, Witek RP, Syn WK, Choi SS, Omenetti A, Premont R, Guy CD, Diehl AM. Signals from dying hepatocytes trigger growth of liver progenitors. Gut 2010; 59: 655-665 [PMID: 20427400 DOI: 10.1136/gut.2009.204354]
-
(2010)
Gut
, vol.59
, pp. 655-665
-
-
Jung, Y.1
Witek, R.P.2
Syn, W.K.3
Choi, S.S.4
Omenetti, A.5
Premont, R.6
Guy, C.D.7
Diehl, A.M.8
-
57
-
-
50249151525
-
The hedgehog pathway regulates remodelling responses to biliary obstruction in rats
-
PMID: 18375471
-
Omenetti A, Popov Y, Jung Y, Choi SS, Witek RP, Yang L, Brown KD, Schuppan D, Diehl AM. The hedgehog pathway regulates remodelling responses to biliary obstruction in rats. Gut 2008; 57: 1275-1282 [PMID: 18375471 DOI: 10.1136/gut.2008.148619]
-
(2008)
Gut
, vol.57
, pp. 1275-1282
-
-
Omenetti, A.1
Popov, Y.2
Jung, Y.3
Choi, S.S.4
Witek, R.P.5
Yang, L.6
Brown, K.D.7
Schuppan, D.8
Diehl, A.M.9
-
58
-
-
77951436593
-
Hedgehog signaling is critical for normal liver regeneration after partial hepatectomy in mice
-
PMID: 20432255
-
Ochoa B, Syn WK, Delgado I, Karaca GF, Jung Y, Wang J, Zubiaga AM, Fresnedo O, Omenetti A, Zdanowicz M, Choi SS, Diehl AM. Hedgehog signaling is critical for normal liver regeneration after partial hepatectomy in mice. Hepatology 2010; 51: 1712-1723 [PMID: 20432255 DOI: 10.1002/hep.23525]
-
(2010)
Hepatology
, vol.51
, pp. 1712-1723
-
-
Ochoa, B.1
Syn, W.K.2
Delgado, I.3
Karaca, G.F.4
Jung, Y.5
Wang, J.6
Zubiaga, A.M.7
Fresnedo, O.8
Omenetti, A.9
Zdanowicz, M.10
Choi, S.S.11
Diehl, A.M.12
-
59
-
-
70349436007
-
Hedgehogmediated epithelial-to-mesenchymal transition and fibrogenic repair in nonalcoholic fatty liver disease
-
PMID: 19577569
-
Syn WK, Jung Y, Omenetti A, Abdelmalek M, Guy CD, Yang L, Wang J, Witek RP, Fearing CM, Pereira TA, Teaberry V, Choi SS, Conde-Vancells J, Karaca GF, Diehl AM. Hedgehogmediated epithelial-to-mesenchymal transition and fibrogenic repair in nonalcoholic fatty liver disease. Gastroenterology 2009; 137: 1478-1488.e8 [PMID: 19577569 DOI: 10.1053/j.gastro.2009.06.051]
-
(2009)
Gastroenterology
, vol.137
, pp. 1478-1488e8
-
-
Syn, W.K.1
Jung, Y.2
Omenetti, A.3
Abdelmalek, M.4
Guy, C.D.5
Yang, L.6
Wang, J.7
Witek, R.P.8
Fearing, C.M.9
Pereira, T.A.10
Teaberry, V.11
Choi, S.S.12
Conde-Vancells, J.13
Karaca, G.F.14
Diehl, A.M.15
-
60
-
-
34248669615
-
Bile ductules and stromal cells express hedgehog ligands and/or hedgehog target genes in primary biliary cirrhosis
-
PMID: 17464985
-
Jung Y, McCall SJ, Li YX, Diehl AM. Bile ductules and stromal cells express hedgehog ligands and/or hedgehog target genes in primary biliary cirrhosis. Hepatology 2007; 45: 1091-1096 [PMID: 17464985 DOI: 10.1002/hep.21660]
-
(2007)
Hepatology
, vol.45
, pp. 1091-1096
-
-
Jung, Y.1
McCall, S.J.2
Li, Y.X.3
Diehl, A.M.4
-
61
-
-
36249016856
-
Hepatic accumulation of Hedgehog-reactive progenitors increases with severity of fatty liver damage in mice
-
PMID: 17952094
-
Fleig SV, Choi SS, Yang L, Jung Y, Omenetti A, VanDongen HM, Huang J, Sicklick JK, Diehl AM. Hepatic accumulation of Hedgehog-reactive progenitors increases with severity of fatty liver damage in mice. Lab Invest 2007; 87: 1227-1239 [PMID: 17952094 DOI: 10.1038/labinvest.3700689]
-
(2007)
Lab Invest
, vol.87
, pp. 1227-1239
-
-
Fleig, S.V.1
Choi, S.S.2
Yang, L.3
Jung, Y.4
Omenetti, A.5
VanDongen, H.M.6
Huang, J.7
Sicklick, J.K.8
Diehl, A.M.9
-
62
-
-
34247369797
-
Hedgehog-mediated mesenchymalepithelial interactions modulate hepatic response to bile duct ligation
-
PMID: 17334411
-
Omenetti A, Yang L, Li YX, McCall SJ, Jung Y, Sicklick JK, Huang J, Choi S, Suzuki A, Diehl AM. Hedgehog-mediated mesenchymalepithelial interactions modulate hepatic response to bile duct ligation. Lab Invest 2007; 87: 499-514 [PMID: 17334411 DOI: 10.1038/labinvest.3700537]
-
(2007)
Lab Invest
, vol.87
, pp. 499-514
-
-
Omenetti, A.1
Yang, L.2
Li, Y.X.3
McCall, S.J.4
Jung, Y.5
Sicklick, J.K.6
Huang, J.7
Choi, S.8
Suzuki, A.9
Diehl, A.M.10
-
63
-
-
0035800521
-
A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA
-
PMID: 11452083
-
Hutvágner G, McLachlan J, Pasquinelli AE, Bálint E, Tuschl T, Zamore PD. A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science 2001; 293: 834-838 [PMID: 11452083 DOI: 10.1126/science.1062961]
-
(2001)
Science
, vol.293
, pp. 834-838
-
-
Hutvágner, G.1
McLachlan, J.2
Pasquinelli, A.E.3
Bálint, E.4
Tuschl, T.5
Zamore, P.D.6
-
64
-
-
0037009364
-
MicroRNA maturation: Stepwise processing and subcellular localization
-
PMID: 12198168
-
Lee Y, Jeon K, Lee JT, Kim S, Kim VN. MicroRNA maturation: stepwise processing and subcellular localization. EMBO J 2002; 21: 4663-4670 [PMID: 12198168 DOI: 10.1093/emboj/cdf476]
-
(2002)
EMBO J
, vol.21
, pp. 4663-4670
-
-
Lee, Y.1
Jeon, K.2
Lee, J.T.3
Kim, S.4
Kim, V.N.5
-
65
-
-
84946490221
-
MicroRNAs promote granule cell expansion in the cerebellum through Gli2
-
PMID: 25910616
-
Constantin L, Wainwright BJ. MicroRNAs Promote Granule Cell Expansion in the Cerebellum Through Gli2. Cerebellum 2015; 14: 688-698 [PMID: 25910616 DOI: 10.1007/s12311-015-0672-x]
-
(2015)
Cerebellum
, vol.14
, pp. 688-698
-
-
Constantin, L.1
Wainwright, B.J.2
-
66
-
-
33646716847
-
The miRNAprocessing enzyme dicer is essential for the morphogenesis and maintenance of hair follicles
-
PMID: 16682203
-
Andl T, Murchison EP, Liu F, Zhang Y, Yunta-Gonzalez M, Tobias JW, Andl CD, Seykora JT, Hannon GJ, Millar SE. The miRNAprocessing enzyme dicer is essential for the morphogenesis and maintenance of hair follicles. Curr Biol 2006; 16: 1041-1049 [PMID: 16682203 DOI: 10.1016/j.cub.2006.04.005]
-
(2006)
Curr Biol
, vol.16
, pp. 1041-1049
-
-
Andl, T.1
Murchison, E.P.2
Liu, F.3
Zhang, Y.4
Yunta-Gonzalez, M.5
Tobias, J.W.6
Andl, C.D.7
Seykora, J.T.8
Hannon, G.J.9
Millar, S.E.10
-
67
-
-
84921824931
-
Temozolomide resistance in glioblastoma occurs by miRNA-9-targeted PTCH1, independent of sonic hedgehog level
-
PMID: 25595896
-
Munoz JL, Rodriguez-Cruz V, Ramkissoon SH, Ligon KL, Greco SJ, Rameshwar P. Temozolomide resistance in glioblastoma occurs by miRNA-9-targeted PTCH1, independent of sonic hedgehog level. Oncotarget 2015; 6: 1190-1201 [PMID: 25595896 DOI: 10.18632/oncotarget.2778]
-
(2015)
Oncotarget
, vol.6
, pp. 1190-1201
-
-
Munoz, J.L.1
Rodriguez-Cruz, V.2
Ramkissoon, S.H.3
Ligon, K.L.4
Greco, S.J.5
Rameshwar, P.6
-
68
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
PMID: 14744438
-
Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004; 116: 281-297 [PMID: 14744438 DOI: 10.1016/S0092-8674(04)00045-5]
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
69
-
-
78650004201
-
MicroRNA: Biogenesis, function and role in cancer
-
PMID: 21532838
-
Macfarlane LA, Murphy PR. MicroRNA: Biogenesis, Function and Role in Cancer. Curr Genomics 2010; 11: 537-561 [PMID: 21532838 DOI: 10.2174/138920210793175895]
-
(2010)
Curr Genomics
, vol.11
, pp. 537-561
-
-
Macfarlane, L.A.1
Murphy, P.R.2
-
70
-
-
84883454644
-
MicroRNAs in liver disease
-
PMID: 23689081
-
Szabo G, Bala S. MicroRNAs in liver disease. Nat Rev Gastroenterol Hepatol 2013; 10: 542-552 [PMID: 23689081 DOI: 10.1038/nrgastro.2013.87]
-
(2013)
Nat Rev Gastroenterol Hepatol
, vol.10
, pp. 542-552
-
-
Szabo, G.1
Bala, S.2
-
71
-
-
84895074732
-
Potential role of Hedgehog signaling and microRNA-29 in liver fibrosis of IKKβ-deficient mouse
-
PMID: 23949847
-
Hyun J, Choi SS, Diehl AM, Jung Y. Potential role of Hedgehog signaling and microRNA-29 in liver fibrosis of IKKβ-deficient mouse. J Mol Histol 2014; 45: 103-112 [PMID: 23949847 DOI: 10.1007/s10735-013-9532-5]
-
(2014)
J Mol Histol
, vol.45
, pp. 103-112
-
-
Hyun, J.1
Choi, S.S.2
Diehl, A.M.3
Jung, Y.4
-
72
-
-
78751476297
-
Micro-RNA profiling reveals a role for miR-29 in human and murine liver fibrosis
-
PMID: 20890893
-
Roderburg C, Urban GW, Bettermann K, Vucur M, Zimmermann H, Schmidt S, Janssen J, Koppe C, Knolle P, Castoldi M, Tacke F, Trautwein C, Luedde T. Micro-RNA profiling reveals a role for miR-29 in human and murine liver fibrosis. Hepatology 2011; 53: 209-218 [PMID: 20890893 DOI: 10.1002/hep.23922]
-
(2011)
Hepatology
, vol.53
, pp. 209-218
-
-
Roderburg, C.1
Urban, G.W.2
Bettermann, K.3
Vucur, M.4
Zimmermann, H.5
Schmidt, S.6
Janssen, J.7
Koppe, C.8
Knolle, P.9
Castoldi, M.10
Tacke, F.11
Trautwein, C.12
Luedde, T.13
-
73
-
-
72749094687
-
Hedgehog pathway activation and epithelial-to-mesenchymal transitions during myofibroblastic transformation of rat hepatic cells in culture and cirrhosis
-
PMID: 19815628
-
Choi SS, Omenetti A, Witek RP, Moylan CA, Syn WK, Jung Y, Yang L, Sudan DL, Sicklick JK, Michelotti GA, Rojkind M, Diehl AM. Hedgehog pathway activation and epithelial-to-mesenchymal transitions during myofibroblastic transformation of rat hepatic cells in culture and cirrhosis. Am J Physiol Gastrointest Liver Physiol 2009; 297: G1093-G1106 [PMID: 19815628 DOI: 10.1152/ajpgi.00292.2009]
-
(2009)
Am J Physiol Gastrointest Liver Physiol
, vol.297
, pp. G1093-G1106
-
-
Choi, S.S.1
Omenetti, A.2
Witek, R.P.3
Moylan, C.A.4
Syn, W.K.5
Jung, Y.6
Yang, L.7
Sudan, D.L.8
Sicklick, J.K.9
Michelotti, G.A.10
Rojkind, M.11
Diehl, A.M.12
-
74
-
-
78449240951
-
Leptin promotes the myofibroblastic phenotype in hepatic stellate cells by activating the hedgehog pathway
-
PMID: 20843817
-
Choi SS, Syn WK, Karaca GF, Omenetti A, Moylan CA, Witek RP, Agboola KM, Jung Y, Michelotti GA, Diehl AM. Leptin promotes the myofibroblastic phenotype in hepatic stellate cells by activating the hedgehog pathway. J Biol Chem 2010; 285: 36551-36560 [PMID: 20843817 DOI: 10.1074/jbc.M110.168542]
-
(2010)
J Biol Chem
, vol.285
, pp. 36551-36560
-
-
Choi, S.S.1
Syn, W.K.2
Karaca, G.F.3
Omenetti, A.4
Moylan, C.A.5
Witek, R.P.6
Agboola, K.M.7
Jung, Y.8
Michelotti, G.A.9
Diehl, A.M.10
-
75
-
-
84945492192
-
Salvianolic acid B-induced microRNA-152 inhibits liver fibrosis by attenuating DNMT1-mediated Patched1 methylation
-
PMID: 26257392
-
Yu F, Lu Z, Chen B, Wu X, Dong P, Zheng J. Salvianolic acid B-induced microRNA-152 inhibits liver fibrosis by attenuating DNMT1-mediated Patched1 methylation. J Cell Mol Med 2015; 19: 2617-2632 [PMID: 26257392 DOI: 10.1111/jcmm.12655]
-
(2015)
J Cell Mol Med
, vol.19
, pp. 2617-2632
-
-
Yu, F.1
Lu, Z.2
Chen, B.3
Wu, X.4
Dong, P.5
Zheng, J.6
-
76
-
-
84946761096
-
MicroRNA-200a suppresses epithelial-to-mesenchymal transition in rat hepatic stellate cells via GLI family zinc finger 2
-
PMID: 26499180
-
Yu F, Zheng Y, Hong W, Chen B, Dong P, Zheng J. MicroRNA-200a suppresses epithelial-to-mesenchymal transition in rat hepatic stellate cells via GLI family zinc finger 2. Mol Med Rep 2015; 12: 8121-8128 [PMID: 26499180 DOI: 10.3892/mmr.2015.4452]
-
(2015)
Mol Med Rep
, vol.12
, pp. 8121-8128
-
-
Yu, F.1
Zheng, Y.2
Hong, W.3
Chen, B.4
Dong, P.5
Zheng, J.6
-
77
-
-
84941788079
-
MicroRNA125b-mediated Hedgehog signaling influences liver regeneration by chorionic platederived mesenchymal stem cells
-
PMID: 26370741
-
Hyun J, Wang S, Kim J, Kim GJ, Jung Y. MicroRNA125b-mediated Hedgehog signaling influences liver regeneration by chorionic platederived mesenchymal stem cells. Sci Rep 2015; 5: 14135 [PMID: 26370741 DOI: 10.1038/srep14135]
-
(2015)
Sci Rep
, vol.5
, pp. 14135
-
-
Hyun, J.1
Wang, S.2
Kim, J.3
Kim, G.J.4
Jung, Y.5
-
78
-
-
84865536179
-
Osteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans
-
PMID: 22488688
-
Pritchett J, Harvey E, Athwal V, Berry A, Rowe C, Oakley F, Moles A, Mann DA, Bobola N, Sharrocks AD, Thomson BJ, Zaitoun AM, Irving WL, Guha IN, Hanley NA, Hanley KP. Osteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans. Hepatology 2012; 56: 1108-1116 [PMID: 22488688 DOI: 10.1002/hep.25758]
-
(2012)
Hepatology
, vol.56
, pp. 1108-1116
-
-
Pritchett, J.1
Harvey, E.2
Athwal, V.3
Berry, A.4
Rowe, C.5
Oakley, F.6
Moles, A.7
Mann, D.A.8
Bobola, N.9
Sharrocks, A.D.10
Thomson, B.J.11
Zaitoun, A.M.12
Irving, W.L.13
Guha, I.N.14
Hanley, N.A.15
Hanley, K.P.16
-
79
-
-
28444449496
-
The microRNA miR-196 acts upstream of Hoxb8 and Shh in limb development
-
PMID: 16319892
-
Hornstein E, Mansfield JH, Yekta S, Hu JK, Harfe BD, McManus MT, Baskerville S, Bartel DP, Tabin CJ. The microRNA miR-196 acts upstream of Hoxb8 and Shh in limb development. Nature 2005; 438: 671-674 [PMID: 16319892 DOI: 10.1038/nature04138]
-
(2005)
Nature
, vol.438
, pp. 671-674
-
-
Hornstein, E.1
Mansfield, J.H.2
Yekta, S.3
Hu, J.K.4
Harfe, B.D.5
McManus, M.T.6
Baskerville, S.7
Bartel, D.P.8
Tabin, C.J.9
-
80
-
-
53549129980
-
Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells
-
PMID: 18756266
-
Ferretti E, De Smaele E, Miele E, Laneve P, Po A, Pelloni M, Paganelli A, Di Marcotullio L, Caffarelli E, Screpanti I, Bozzoni I, Gulino A. Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells. EMBO J 2008; 27: 2616-2627 [PMID: 18756266 DOI: 10.1038/emboj.2008.172]
-
(2008)
EMBO J
, vol.27
, pp. 2616-2627
-
-
Ferretti, E.1
De Smaele, E.2
Miele, E.3
Laneve, P.4
Po, A.5
Pelloni, M.6
Paganelli, A.7
Di Marcotullio, L.8
Caffarelli, E.9
Screpanti, I.10
Bozzoni, I.11
Gulino, A.12
-
81
-
-
77954950168
-
Transcriptional suppression of mir-29b-1/mir-29a promoter by c-Myc, hedgehog, and NF-kappaB
-
PMID: 20564213
-
Mott JL, Kurita S, Cazanave SC, Bronk SF, Werneburg NW, Fernandez-Zapico ME. Transcriptional suppression of mir-29b-1/mir-29a promoter by c-Myc, hedgehog, and NF-kappaB. J Cell Biochem 2010; 110: 1155-1164 [PMID: 20564213 DOI: 10.1002/jcb.22630]
-
(2010)
J Cell Biochem
, vol.110
, pp. 1155-1164
-
-
Mott, J.L.1
Kurita, S.2
Cazanave, S.C.3
Bronk, S.F.4
Werneburg, N.W.5
Fernandez-Zapico, M.E.6
-
82
-
-
80051784270
-
Suppression of hepatic stellate cell activation by microRNA-29b
-
PMID: 21798245
-
Sekiya Y, Ogawa T, Yoshizato K, Ikeda K, Kawada N. Suppression of hepatic stellate cell activation by microRNA-29b. Biochem Biophys Res Commun 2011; 412: 74-79 [PMID: 21798245 DOI: 10.1016/j.bbrc.2011.07.041]
-
(2011)
Biochem Biophys Res Commun
, vol.412
, pp. 74-79
-
-
Sekiya, Y.1
Ogawa, T.2
Yoshizato, K.3
Ikeda, K.4
Kawada, N.5
-
83
-
-
35948958955
-
TLR4 enhances TGF-beta signaling and hepatic fibrosis
-
PMID: 17952090
-
Seki E, De Minicis S, Osterreicher CH, Kluwe J, Osawa Y, Brenner DA, Schwabe RF. TLR4 enhances TGF-beta signaling and hepatic fibrosis. Nat Med 2007; 13: 1324-1332 [PMID: 17952090 DOI: 10.1038/nm1663]
-
(2007)
Nat Med
, vol.13
, pp. 1324-1332
-
-
Seki, E.1
De Minicis, S.2
Osterreicher, C.H.3
Kluwe, J.4
Osawa, Y.5
Brenner, D.A.6
Schwabe, R.F.7
-
84
-
-
34548687035
-
Gores GJ. Mir-29 regulates Mcl-1 protein expression and apoptosis
-
PMID: 17404574
-
Mott JL, Kobayashi S, Bronk SF, Gores GJ. mir-29 regulates Mcl-1 protein expression and apoptosis. Oncogene 2007; 26: 6133-6140 [PMID: 17404574 DOI: 10.1038/sj.onc.1210436]
-
(2007)
Oncogene
, vol.26
, pp. 6133-6140
-
-
Mott, J.L.1
Kobayashi, S.2
Bronk, S.F.3
-
85
-
-
77950602604
-
Effects of microRNA-29 on apoptosis, tumorigenicity, and prognosis of hepatocellular carcinoma
-
PMID: 20041405
-
Xiong Y, Fang JH, Yun JP, Yang J, Zhang Y, Jia WH, Zhuang SM. Effects of microRNA-29 on apoptosis, tumorigenicity, and prognosis of hepatocellular carcinoma. Hepatology 2010; 51: 836-845 [PMID: 20041405 DOI: 10.1002/hep.23380]
-
(2010)
Hepatology
, vol.51
, pp. 836-845
-
-
Xiong, Y.1
Fang, J.H.2
Yun, J.P.3
Yang, J.4
Zhang, Y.5
Jia, W.H.6
Zhuang, S.M.7
-
86
-
-
77955435090
-
Chronic lymphocytic leukemia modeled in mouse by targeted miR-29 expression
-
PMID: 20566844
-
Santanam U, Zanesi N, Efanov A, Costinean S, Palamarchuk A, Hagan JP, Volinia S, Alder H, Rassenti L, Kipps T, Croce CM, Pekarsky Y. Chronic lymphocytic leukemia modeled in mouse by targeted miR-29 expression. Proc Natl Acad Sci USA 2010; 107: 12210-12215 [PMID: 20566844 DOI: 10.1073/pnas.1007186107]
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 12210-12215
-
-
Santanam, U.1
Zanesi, N.2
Efanov, A.3
Costinean, S.4
Palamarchuk, A.5
Hagan, J.P.6
Volinia, S.7
Alder, H.8
Rassenti, L.9
Kipps, T.10
Croce, C.M.11
Pekarsky, Y.12
-
87
-
-
78649674133
-
Correlation between microRNA expression levels and clinical parameters associated with chronic hepatitis C viral infection in humans
-
PMID: 20625373
-
Marquez RT, Bandyopadhyay S, Wendlandt EB, Keck K, Hoffer BA, Icardi MS, Christensen RN, Schmidt WN, McCaffrey AP. Correlation between microRNA expression levels and clinical parameters associated with chronic hepatitis C viral infection in humans. Lab Invest 2010; 90: 1727-1736 [PMID: 20625373 DOI: 10.1038/labinvest.2010.126]
-
(2010)
Lab Invest
, vol.90
, pp. 1727-1736
-
-
Marquez, R.T.1
Bandyopadhyay, S.2
Wendlandt, E.B.3
Keck, K.4
Hoffer, B.A.5
Icardi, M.S.6
Christensen, R.N.7
Schmidt, W.N.8
McCaffrey, A.P.9
-
88
-
-
84878343722
-
NPV-LDE-225 (Erismodegib) inhibits epithelial mesenchymal transition and self-renewal of glioblastoma initiating cells by regulating miR-21, miR-128, and miR-200
-
PMID: 23482671
-
Fu J, Rodova M, Nanta R, Meeker D, Van Veldhuizen PJ, Srivastava RK, Shankar S. NPV-LDE-225 (Erismodegib) inhibits epithelial mesenchymal transition and self-renewal of glioblastoma initiating cells by regulating miR-21, miR-128, and miR-200. Neuro Oncol 2013; 15: 691-706 [PMID: 23482671 DOI: 10.1093/neuonc/not011]
-
(2013)
Neuro Oncol
, vol.15
, pp. 691-706
-
-
Fu, J.1
Rodova, M.2
Nanta, R.3
Meeker, D.4
Van Veldhuizen, P.J.5
Srivastava, R.K.6
Shankar, S.7
-
89
-
-
80055042635
-
Up-regulation of Hedgehog pathway is associated with cellular permissiveness for hepatitis C virus replication
-
PMID: 21793033
-
Choi SS, Bradrick S, Qiang G, Mostafavi A, Chaturvedi G, Weinman SA, Diehl AM, Jhaveri R. Up-regulation of Hedgehog pathway is associated with cellular permissiveness for hepatitis C virus replication. Hepatology 2011; 54: 1580-1590 [PMID: 21793033 DOI: 10.1002/hep.24576]
-
(2011)
Hepatology
, vol.54
, pp. 1580-1590
-
-
Choi, S.S.1
Bradrick, S.2
Qiang, G.3
Mostafavi, A.4
Chaturvedi, G.5
Weinman, S.A.6
Diehl, A.M.7
Jhaveri, R.8
-
90
-
-
78649641423
-
Viral factors induce Hedgehog pathway activation in humans with viral hepatitis, cirrhosis, and hepatocellular carcinoma
-
PMID: 20697376
-
Pereira Tde A, Witek RP, Syn WK, Choi SS, Bradrick S, Karaca GF, Agboola KM, Jung Y, Omenetti A, Moylan CA, Yang L, Fernandez-Zapico ME, Jhaveri R, Shah VH, Pereira FE, Diehl AM. Viral factors induce Hedgehog pathway activation in humans with viral hepatitis, cirrhosis, and hepatocellular carcinoma. Lab Invest 2010; 90: 1690-1703 [PMID: 20697376 DOI: 10.1038/labinvest.2010.147]
-
(2010)
Lab Invest
, vol.90
, pp. 1690-1703
-
-
Pereira Tde, A.1
Witek, R.P.2
Syn, W.K.3
Choi, S.S.4
Bradrick, S.5
Karaca, G.F.6
Agboola, K.M.7
Jung, Y.8
Omenetti, A.9
Moylan, C.A.10
Yang, L.11
Fernandez-Zapico, M.E.12
Jhaveri, R.13
Shah, V.H.14
Pereira, F.E.15
Diehl, A.M.16
-
91
-
-
80052203143
-
TGF-β/SMAD/GLI2 signaling axis in cancer progression and metastasis
-
PMID: 21862631
-
Javelaud D, Alexaki VI, Dennler S, Mohammad KS, Guise TA, Mauviel A. TGF-β/SMAD/GLI2 signaling axis in cancer progression and metastasis. Cancer Res 2011; 71: 5606-5610 [PMID: 21862631 DOI: 10.1158/0008-5472.CAN-11-1194]
-
(2011)
Cancer Res
, vol.71
, pp. 5606-5610
-
-
Javelaud, D.1
Alexaki, V.I.2
Dennler, S.3
Mohammad, K.S.4
Guise, T.A.5
Mauviel, A.6
-
92
-
-
34547120220
-
Induction of sonic hedgehog mediators by transforming growth factor-beta: Smad3-dependent activation of Gli2 and Gli1 expression in vitro and in vivo
-
PMID: 17638910
-
Dennler S, André J, Alexaki I, Li A, Magnaldo T, ten Dijke P, Wang XJ, Verrecchia F, Mauviel A. Induction of sonic hedgehog mediators by transforming growth factor-beta: Smad3-dependent activation of Gli2 and Gli1 expression in vitro and in vivo. Cancer Res 2007; 67: 6981-6986 [PMID: 17638910 DOI: 10.1158/0008-5472. CAN-07-0491]
-
(2007)
Cancer Res
, vol.67
, pp. 6981-6986
-
-
Dennler, S.1
André, J.2
Alexaki, I.3
Li, A.4
Magnaldo, T.5
Ten Dijke, P.6
Wang, X.J.7
Verrecchia, F.8
Mauviel, A.9
-
93
-
-
84864011802
-
MicroRNA-146a modulates TGF-beta1-induced hepatic stellate cell proliferation by targeting SMAD4
-
PMID: 22735812
-
He Y, Huang C, Sun X, Long XR, Lv XW, Li J. MicroRNA-146a modulates TGF-beta1-induced hepatic stellate cell proliferation by targeting SMAD4. Cell Signal 2012; 24: 1923-1930 [PMID: 22735812 DOI: 10.1016/j.cellsig.2012.06.003]
-
(2012)
Cell Signal
, vol.24
, pp. 1923-1930
-
-
He, Y.1
Huang, C.2
Sun, X.3
Long, X.R.4
Lv, X.W.5
Li, J.6
-
94
-
-
84887833141
-
NOD2-nitric oxide-responsive microRNA-146a activates Sonic hedgehog signaling to orchestrate inflammatory responses in murine model of inflammatory bowel disease
-
PMID: 24092752
-
Ghorpade DS, Sinha AY, Holla S, Singh V, Balaji KN. NOD2-nitric oxide-responsive microRNA-146a activates Sonic hedgehog signaling to orchestrate inflammatory responses in murine model of inflammatory bowel disease. J Biol Chem 2013; 288: 33037-33048 [PMID: 24092752 DOI: 10.1074/jbc.M113.492496]
-
(2013)
J Biol Chem
, vol.288
, pp. 33037-33048
-
-
Ghorpade, D.S.1
Sinha, A.Y.2
Holla, S.3
Singh, V.4
Balaji, K.N.5
-
95
-
-
18144388632
-
Regulation and function of the sonic hedgehog signal transduction pathway in isolated gastric parietal cells
-
PMID: 15691835
-
Stepan V, Ramamoorthy S, Nitsche H, Zavros Y, Merchant JL, Todisco A. Regulation and function of the sonic hedgehog signal transduction pathway in isolated gastric parietal cells. J Biol Chem 2005; 280: 15700-15708 [PMID: 15691835 DOI: 10.1074/jbc. M413037200]
-
(2005)
J Biol Chem
, vol.280
, pp. 15700-15708
-
-
Stepan, V.1
Ramamoorthy, S.2
Nitsche, H.3
Zavros, Y.4
Merchant, J.L.5
Todisco, A.6
-
96
-
-
32444449871
-
GLI transcription factors: Mediators of oncogenic Hedgehog signalling
-
PMID: 16406505
-
Kasper M, Regl G, Frischauf AM, Aberger F. GLI transcription factors: mediators of oncogenic Hedgehog signalling. Eur J Cancer 2006; 42: 437-445 [PMID: 16406505 DOI: 10.1016/j.ejca.2005.08.039]
-
(2006)
Eur J Cancer
, vol.42
, pp. 437-445
-
-
Kasper, M.1
Regl, G.2
Frischauf, A.M.3
Aberger, F.4
-
97
-
-
33749368571
-
The therapeutic potential of modulators of the Hedgehog-Gli signaling pathway
-
PMID: 12437768
-
Stecca B, Ruiz i Altaba A. The therapeutic potential of modulators of the Hedgehog-Gli signaling pathway. J Biol 2002; 1: 9 [PMID: 12437768 DOI: 10.1186/1475-4924-1-9]
-
(2002)
J Biol
, vol.1
, pp. 9
-
-
Stecca, B.1
Ruizi Altaba, A.2
-
98
-
-
33751264968
-
Synthetic microRNA designed to target glioma-associated antigen 1 transcription factor inhibits division and induces late apoptosis in pancreatic tumor cells
-
PMID: 17085671
-
Tsuda N, Ishiyama S, Li Y, Ioannides CG, Abbruzzese JL, Chang DZ. Synthetic microRNA designed to target glioma-associated antigen 1 transcription factor inhibits division and induces late apoptosis in pancreatic tumor cells. Clin Cancer Res 2006; 12: 6557-6564 [PMID: 17085671 DOI: 10.1158/1078-0432. CCR-06-0588]
-
(2006)
Clin Cancer Res
, vol.12
, pp. 6557-6564
-
-
Tsuda, N.1
Ishiyama, S.2
Li, Y.3
Ioannides, C.G.4
Abbruzzese, J.L.5
Chang, D.Z.6
-
99
-
-
64549085589
-
Synthetic microRNA targeting glioma-associated antigen-1 protein
-
PMID: 19301660
-
Tsuda N, Mine T, Ioannides CG, Chang DZ. Synthetic microRNA targeting glioma-associated antigen-1 protein. Methods Mol Biol 2009; 487: 435-449 [PMID: 19301660 DOI: 10.1007/978-1-60327-547-7-21]
-
(2009)
Methods Mol Biol
, vol.487
, pp. 435-449
-
-
Tsuda, N.1
Mine, T.2
Ioannides, C.G.3
Chang, D.Z.4
-
101
-
-
80052420490
-
Hedgehog signaling antagonist promotes regression of both liver fibrosis and hepatocellular carcinoma in a murine model of primary liver cancer
-
PMID: 21912653
-
Philips GM, Chan IS, Swiderska M, Schroder VT, Guy C, Karaca GF, Moylan C, Venkatraman T, Feuerlein S, Syn WK, Jung Y, Witek RP, Choi S, Michelotti GA, Rangwala F, Merkle E, Lascola C, Diehl AM. Hedgehog signaling antagonist promotes regression of both liver fibrosis and hepatocellular carcinoma in a murine model of primary liver cancer. PLoS One 2011; 6: e23943 [PMID: 21912653 DOI: 10.1371/journal.pone.0023943]
-
(2011)
PLoS One
, vol.6
, pp. e23943
-
-
Philips, G.M.1
Chan, I.S.2
Swiderska, M.3
Schroder, V.T.4
Guy, C.5
Karaca, G.F.6
Moylan, C.7
Venkatraman, T.8
Feuerlein, S.9
Syn, W.K.10
Jung, Y.11
Witek, R.P.12
Choi, S.13
Michelotti, G.A.14
Rangwala, F.15
Merkle, E.16
Lascola, C.17
Diehl, A.M.18
-
102
-
-
84880651918
-
Vismodegib suppresses TRAIL-mediated liver injury in a mouse model of nonalcoholic steatohepatitis
-
PMID: 23894677
-
Hirsova P, Ibrahim SH, Bronk SF, Yagita H, Gores GJ. Vismodegib suppresses TRAIL-mediated liver injury in a mouse model of nonalcoholic steatohepatitis. PLoS One 2013; 8: e70599 [PMID: 23894677 DOI: 10.1371/journal.pone.0070599]
-
(2013)
PLoS One
, vol.8
, pp. e70599
-
-
Hirsova, P.1
Ibrahim, S.H.2
Bronk, S.F.3
Yagita, H.4
Gores, G.J.5
-
103
-
-
84868221814
-
Hedgehog pathway inhibitors-Current status and future prospects
-
PMID: 23116301
-
Sheikh A, Alvi AA, Aslam HM, Haseeb A. Hedgehog pathway inhibitors-current status and future prospects. Infect Agent Cancer 2012; 7: 29 [PMID: 23116301 DOI: 10.1186/1750-9378-7-29]
-
(2012)
Infect Agent Cancer
, vol.7
, pp. 29
-
-
Sheikh, A.1
Alvi, A.A.2
Aslam, H.M.3
Haseeb, A.4
-
105
-
-
84961206588
-
Co-delivery of small molecule hedgehog inhibitor and miRNA for treating liver fibrosis
-
PMID: 26524535
-
Kumar V, Mondal G, Dutta R, Mahato RI. Co-delivery of small molecule hedgehog inhibitor and miRNA for treating liver fibrosis. Biomaterials 2016; 76: 144-156 [PMID: 26524535 DOI: 10.1016/j.biomaterials.2015.10.047]
-
(2016)
Biomaterials
, vol.76
, pp. 144-156
-
-
Kumar, V.1
Mondal, G.2
Dutta, R.3
Mahato, R.I.4
-
106
-
-
83255186696
-
MicroRNA therapeutics
-
PMID: 21525952
-
Broderick JA, Zamore PD. MicroRNA therapeutics. Gene Ther 2011; 18: 1104-1110 [PMID: 21525952 DOI: 10.1038/gt.2011.50]
-
(2011)
Gene Ther
, vol.18
, pp. 1104-1110
-
-
Broderick, J.A.1
Zamore, P.D.2
-
107
-
-
84856751210
-
Developing microRNA therapeutics
-
PMID: 22302756
-
van Rooij E, Purcell AL, Levin AA. Developing microRNA therapeutics. Circ Res 2012; 110: 496-507 [PMID: 22302756 DOI: 10.1161/CIRCRESAHA.111.247916]
-
(2012)
Circ Res
, vol.110
, pp. 496-507
-
-
Van Rooij, E.1
Purcell, A.L.2
Levin, A.A.3
-
108
-
-
84903717510
-
Development of microRNA therapeutics is coming of age
-
PMID: 24935956
-
van Rooij E, Kauppinen S. Development of microRNA therapeutics is coming of age. EMBO Mol Med 2014; 6: 851-864 [PMID: 24935956 DOI: 10.15252/emmm.201100899]
-
(2014)
EMBO Mol Med
, vol.6
, pp. 851-864
-
-
Van Rooij, E.1
Kauppinen, S.2
-
109
-
-
84891765459
-
Miravirsen (SPC3649) can inhibit the biogenesis of miR-122
-
PMID: 24068553
-
Gebert LF, Rebhan MA, Crivelli SE, Denzler R, Stoffel M, Hall J. Miravirsen (SPC3649) can inhibit the biogenesis of miR-122. Nucleic Acids Res 2014; 42: 609-621 [PMID: 24068553 DOI: 10.1093/nar/gkt852]
-
(2014)
Nucleic Acids Res
, vol.42
, pp. 609-621
-
-
Gebert, L.F.1
Rebhan, M.A.2
Crivelli, S.E.3
Denzler, R.4
Stoffel, M.5
Hall, J.6
-
110
-
-
84885065624
-
First microRNA mimic enters clinic
-
PMID: 23839128
-
Bouchie A. First microRNA mimic enters clinic. Nat Biotechnol 2013; 31: 577 [PMID: 23839128 DOI: 10.1038/nbt0713-577]
-
(2013)
Nat Biotechnol
, vol.31
, pp. 577
-
-
Bouchie, A.1
-
111
-
-
84905904910
-
MicroRNA-101 suppresses liver fibrosis by targeting the TGFβ signalling pathway
-
PMID: 24817606
-
Tu X, Zhang H, Zhang J, Zhao S, Zheng X, Zhang Z, Zhu J, Chen J, Dong L, Zang Y, Zhang J. MicroRNA-101 suppresses liver fibrosis by targeting the TGFβ signalling pathway. J Pathol 2014; 234: 46-59 [PMID: 24817606 DOI: 10.1002/path.4373]
-
(2014)
J Pathol
, vol.234
, pp. 46-59
-
-
Tu, X.1
Zhang, H.2
Zhang, J.3
Zhao, S.4
Zheng, X.5
Zhang, Z.6
Zhu, J.7
Chen, J.8
Dong, L.9
Zang, Y.10
Zhang, J.11
-
112
-
-
84943279279
-
MiR-142-5p and miR-130a-3p are regulated by IL-4 and IL-13 and control profibrogenic macrophage program
-
PMID: 26436920
-
Su S, Zhao Q, He C, Huang D, Liu J, Chen F, Chen J, Liao JY, Cui X, Zeng Y, Yao H, Su F, Liu Q, Jiang S, Song E. miR-142-5p and miR-130a-3p are regulated by IL-4 and IL-13 and control profibrogenic macrophage program. Nat Commun 2015; 6: 8523 [PMID: 26436920 DOI: 10.1038/ncomms9523]
-
(2015)
Nat Commun
, vol.6
, pp. 8523
-
-
Su, S.1
Zhao, Q.2
He, C.3
Huang, D.4
Liu, J.5
Chen, F.6
Chen, J.7
Liao, J.Y.8
Cui, X.9
Zeng, Y.10
Yao, H.11
Su, F.12
Liu, Q.13
Jiang, S.14
Song, E.15
-
113
-
-
84887150782
-
Progress in microRNA delivery
-
PMID: 24075926
-
Zhang Y, Wang Z, Gemeinhart RA. Progress in microRNA delivery. J Control Release 2013; 172: 962-974 [PMID: 24075926 DOI: 10.1016/j.jconrel.2013.09.015]
-
(2013)
J Control Release
, vol.172
, pp. 962-974
-
-
Zhang, Y.1
Wang, Z.2
Gemeinhart, R.A.3
-
114
-
-
84939651110
-
MicroRNA-125b attenuates epithelial-mesenchymal transitions and targets stemlike liver cancer cells through small mothers against decapentaplegic 2 and 4
-
PMID: 25953743
-
Zhou JN, Zeng Q, Wang HY, Zhang B, Li ST, Nan X, Cao N, Fu CJ, Yan XL, Jia YL, Wang JX, Zhao AH, Li ZW, Li YH, Xie XY, Zhang XM, Dong Y, Xu YC, He LJ, Yue W, Pei XT. MicroRNA-125b attenuates epithelial-mesenchymal transitions and targets stemlike liver cancer cells through small mothers against decapentaplegic 2 and 4. Hepatology 2015; 62: 801-815 [PMID: 25953743 DOI: 10.1002/hep.27887]
-
(2015)
Hepatology
, vol.62
, pp. 801-815
-
-
Zhou, J.N.1
Zeng, Q.2
Wang, H.Y.3
Zhang, B.4
Li, S.T.5
Nan, X.6
Cao, N.7
Fu, C.J.8
Yan, X.L.9
Jia, Y.L.10
Wang, J.X.11
Zhao, A.H.12
Li, Z.W.13
Li, Y.H.14
Xie, X.Y.15
Zhang, X.M.16
Dong, Y.17
Xu, Y.C.18
He, L.J.19
Yue, W.20
Pei, X.T.21
more..
-
115
-
-
84937565249
-
Non viral vectors in gene therapy-an overview
-
PMID: 25738007
-
Ramamoorth M, Narvekar A. Non viral vectors in gene therapy-an overview. J Clin Diagn Res 2015; 9: GE01-GE06 [PMID: 25738007 DOI: 10.7860/JCDR/2015/10443.5394]
-
(2015)
J Clin Diagn Res
, vol.9
, pp. GE01-GE06
-
-
Ramamoorth, M.1
Narvekar, A.2
-
116
-
-
33745460260
-
Current status of polymeric gene delivery systems
-
PMID: 16781003
-
Park TG, Jeong JH, Kim SW. Current status of polymeric gene delivery systems. Adv Drug Deliv Rev 2006; 58: 467-486 [PMID: 16781003 DOI: 10.1016/j.addr.2006.03.007]
-
(2006)
Adv Drug Deliv Rev
, vol.58
, pp. 467-486
-
-
Park, T.G.1
Jeong, J.H.2
Kim, S.W.3
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