-
1
-
-
84866337171
-
Cytokines and STATs in liver fibrosis
-
Kong X, Horiguchi N, Mori M, et al. Cytokines and STATs in liver fibrosis. Front Physiol. 2012; 3: 69.
-
(2012)
Front Physiol
, vol.3
, pp. 69
-
-
Kong, X.1
Horiguchi, N.2
Mori, M.3
-
2
-
-
80052556495
-
Hepatocyte growth factor (HGF) inhibits collagen I and IV synthesis in hepatic stellate cells by miRNA-29 induction
-
Kwiecinski M, Noetel A, Elfimova N, et al. Hepatocyte growth factor (HGF) inhibits collagen I and IV synthesis in hepatic stellate cells by miRNA-29 induction. PLoS ONE. 2011; 6: e24568.
-
(2011)
PLoS ONE
, vol.6
, pp. e24568
-
-
Kwiecinski, M.1
Noetel, A.2
Elfimova, N.3
-
3
-
-
84865654208
-
The potential of microRNAs in liver fibrosis
-
He Y, Huang C, Zhang SP, et al. The potential of microRNAs in liver fibrosis. Cell Signal. 2012; 24: 2268-72.
-
(2012)
Cell Signal
, vol.24
, pp. 2268-2272
-
-
He, Y.1
Huang, C.2
Zhang, S.P.3
-
4
-
-
33645302628
-
The epithelial-mesenchymal transition: new insights in signaling, development, and disease
-
Lee JM, Dedhar S, Kalluri R, et al. The epithelial-mesenchymal transition: new insights in signaling, development, and disease. J Cell Biol. 2006; 172: 973-81.
-
(2006)
J Cell Biol
, vol.172
, pp. 973-981
-
-
Lee, J.M.1
Dedhar, S.2
Kalluri, R.3
-
5
-
-
0034723290
-
Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury
-
Friedman SL. Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury. J Biol Chem. 2000; 275: 2247-50.
-
(2000)
J Biol Chem
, vol.275
, pp. 2247-2250
-
-
Friedman, S.L.1
-
6
-
-
78449240951
-
Leptin promotes the myofibroblastic phenotype in hepatic stellate cells by activating the hedgehog pathway
-
Choi SS, Syn WK, Karaca GF, et al. Leptin promotes the myofibroblastic phenotype in hepatic stellate cells by activating the hedgehog pathway. J Biol Chem. 2010; 285: 36551-60.
-
(2010)
J Biol Chem
, vol.285
, pp. 36551-36560
-
-
Choi, S.S.1
Syn, W.K.2
Karaca, G.F.3
-
7
-
-
33645293425
-
In vitro protective effects of salvianolic acid B on primary hepatocytes and hepatic stellate cells
-
Lin YL, Wu CH, Luo MH, et al. In vitro protective effects of salvianolic acid B on primary hepatocytes and hepatic stellate cells. J Ethnopharmacol. 2006; 105: 215-22.
-
(2006)
J Ethnopharmacol
, vol.105
, pp. 215-222
-
-
Lin, Y.L.1
Wu, C.H.2
Luo, M.H.3
-
8
-
-
0036678553
-
Clinical observation of salvianolic acid B in treatment of liver fibrosis in chronic hepatitis B
-
Liu P, Hu YY, Liu C, et al. Clinical observation of salvianolic acid B in treatment of liver fibrosis in chronic hepatitis B. World J Gastroenterol. 2002; 8: 679-85.
-
(2002)
World J Gastroenterol
, vol.8
, pp. 679-685
-
-
Liu, P.1
Hu, Y.Y.2
Liu, C.3
-
9
-
-
33645085904
-
Effects of salvianolic acid B on expressions of TGF-beta1 and its receptors in liver of rats with dimethylnitrosamine-induced hepatic fibrosis
-
Wang XN, Hu YY, Liu CH, et al. Effects of salvianolic acid B on expressions of TGF-beta1 and its receptors in liver of rats with dimethylnitrosamine-induced hepatic fibrosis. Zhong Xi Yi Jie He Xue Bao. 2005; 3: 286-9.
-
(2005)
Zhong Xi Yi Jie He Xue Bao
, vol.3
, pp. 286-289
-
-
Wang, X.N.1
Hu, Y.Y.2
Liu, C.H.3
-
10
-
-
72749094687
-
Hedgehog pathway activation and epithelial-to-mesenchymal transitions during myofibroblastic transformation of rat hepatic cells in culture and cirrhosis
-
Choi SS, Omenetti A, Witek RP, et al. Hedgehog pathway activation and epithelial-to-mesenchymal transitions during myofibroblastic transformation of rat hepatic cells in culture and cirrhosis. Am J Physiol Gastrointest Liver Physiol. 2009; 297: G1093-106.
-
(2009)
Am J Physiol Gastrointest Liver Physiol
, vol.297
, pp. G1093-G1106
-
-
Choi, S.S.1
Omenetti, A.2
Witek, R.P.3
-
11
-
-
84902333290
-
Role of PTCH1 gene methylation in gastric carcinogenesis
-
Zuo Y, Song Y, Zhang M, et al. Role of PTCH1 gene methylation in gastric carcinogenesis. Oncol Lett. 2014; 8: 679-82.
-
(2014)
Oncol Lett
, vol.8
, pp. 679-682
-
-
Zuo, Y.1
Song, Y.2
Zhang, M.3
-
12
-
-
84875101328
-
DNA methylation and MeCP2 regulation of PTCH1 expression during rats hepatic fibrosis
-
Yang JJ, Tao H, Huang C, et al. DNA methylation and MeCP2 regulation of PTCH1 expression during rats hepatic fibrosis. Cell Signal. 2013; 25: 1202-11.
-
(2013)
Cell Signal
, vol.25
, pp. 1202-1211
-
-
Yang, J.J.1
Tao, H.2
Huang, C.3
-
13
-
-
15744401773
-
Eukaryotic cytosine methyltransferases
-
Goll MG, Bestor TH. Eukaryotic cytosine methyltransferases. Annu Rev Biochem. 2005; 74: 481-514.
-
(2005)
Annu Rev Biochem
, vol.74
, pp. 481-514
-
-
Goll, M.G.1
Bestor, T.H.2
-
14
-
-
15744396813
-
The key to development: interpreting the histone code?
-
Margueron R, Trojer P, Reinberg D. The key to development: interpreting the histone code? Curr Opin Genet Dev. 2005; 15: 163-76.
-
(2005)
Curr Opin Genet Dev
, vol.15
, pp. 163-176
-
-
Margueron, R.1
Trojer, P.2
Reinberg, D.3
-
15
-
-
84893869571
-
Participation of miR-200a in TGF-beta1-mediated hepatic stellate cell activation
-
Sun X, He Y, Ma TT, et al. Participation of miR-200a in TGF-beta1-mediated hepatic stellate cell activation. Mol Cell Biochem. 2014; 388: 11-23.
-
(2014)
Mol Cell Biochem
, vol.388
, pp. 11-23
-
-
Sun, X.1
He, Y.2
Ma, T.T.3
-
16
-
-
38349169664
-
Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?
-
Filipowicz W, Bhattacharyya SN, Sonenberg N. Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat Rev Genet. 2008; 9: 102-14.
-
(2008)
Nat Rev Genet
, vol.9
, pp. 102-114
-
-
Filipowicz, W.1
Bhattacharyya, S.N.2
Sonenberg, N.3
-
17
-
-
0347444723
-
MicroRNAs: genomics, biogenesis, mechanism, and function
-
Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004; 116: 281-97.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
18
-
-
84865255059
-
microRNA are central players in anti- and profibrotic gene regulation during liver fibrosis
-
Noetel A, Kwiecinski M, Elfimova N, et al. microRNA are central players in anti- and profibrotic gene regulation during liver fibrosis. Front Physiol. 2012; 3: 49.
-
(2012)
Front Physiol
, vol.3
, pp. 49
-
-
Noetel, A.1
Kwiecinski, M.2
Elfimova, N.3
-
19
-
-
84933060092
-
MicroRNA-17-5p activates hepatic stellate cells through targeting of Smad7
-
Yu F, Guo Y, Chen B, et al. MicroRNA-17-5p activates hepatic stellate cells through targeting of Smad7. Lab Invest. 2015; 95: 781-9.
-
(2015)
Lab Invest
, vol.95
, pp. 781-789
-
-
Yu, F.1
Guo, Y.2
Chen, B.3
-
20
-
-
80051784270
-
Suppression of hepatic stellate cell activation by microRNA-29b
-
Sekiya Y, Ogawa T, Yoshizato K, et al. Suppression of hepatic stellate cell activation by microRNA-29b. Biochem Biophys Res Commun. 2011; 412: 74-9.
-
(2011)
Biochem Biophys Res Commun
, vol.412
, pp. 74-79
-
-
Sekiya, Y.1
Ogawa, T.2
Yoshizato, K.3
-
21
-
-
67650588646
-
MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1
-
Garzon R, Liu S, Fabbri M, et al. MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1. Blood. 2009; 113: 6411-8.
-
(2009)
Blood
, vol.113
, pp. 6411-6418
-
-
Garzon, R.1
Liu, S.2
Fabbri, M.3
-
22
-
-
84891827132
-
Curcumin up-regulates phosphatase and tensin homologue deleted on chromosome 10 through microRNA-mediated control of DNA methylation-a novel mechanism suppressing liver fibrosis
-
Zheng J, Wu C, Lin Z, et al. Curcumin up-regulates phosphatase and tensin homologue deleted on chromosome 10 through microRNA-mediated control of DNA methylation-a novel mechanism suppressing liver fibrosis. FEBS J. 2014; 281: 88-103.
-
(2014)
FEBS J
, vol.281
, pp. 88-103
-
-
Zheng, J.1
Wu, C.2
Lin, Z.3
-
23
-
-
33747797033
-
Hepatic stellate cells express synemin, a protein bridging intermediate filaments to focal adhesions
-
Uyama N, Zhao L, Van Rossen E, et al. Hepatic stellate cells express synemin, a protein bridging intermediate filaments to focal adhesions. Gut. 2006; 55: 1276-89.
-
(2006)
Gut
, vol.55
, pp. 1276-1289
-
-
Uyama, N.1
Zhao, L.2
Van Rossen, E.3
-
24
-
-
84887193824
-
Salvianolic acid B inhibits hepatic stellate cell activation through transforming growth factor beta-1 signal transduction pathway in vivo and in vitro
-
Tao YY, Wang QL, Shen L, et al. Salvianolic acid B inhibits hepatic stellate cell activation through transforming growth factor beta-1 signal transduction pathway in vivo and in vitro. Exp Biol Med. 2013; 238: 1284-96.
-
(2013)
Exp Biol Med
, vol.238
, pp. 1284-1296
-
-
Tao, Y.Y.1
Wang, Q.L.2
Shen, L.3
-
25
-
-
84883136861
-
Knockdown of N-acetylglucosaminyl transferase V ameliorates hepatotoxin-induced liver fibrosis in mice
-
Liu J, Zhang Z, Tu X, et al. Knockdown of N-acetylglucosaminyl transferase V ameliorates hepatotoxin-induced liver fibrosis in mice. Toxicol Sci. 2013; 135: 144-55.
-
(2013)
Toxicol Sci
, vol.135
, pp. 144-155
-
-
Liu, J.1
Zhang, Z.2
Tu, X.3
-
26
-
-
84904272085
-
Salvianolic acid B inhibited PPARgamma expression and attenuated weight gain in mice with high-fat diet-induced obesity
-
Wang P, Xu S, Li W, et al. Salvianolic acid B inhibited PPARgamma expression and attenuated weight gain in mice with high-fat diet-induced obesity. Cell Physiol Biochem. 2014; 34: 288-98.
-
(2014)
Cell Physiol Biochem
, vol.34
, pp. 288-298
-
-
Wang, P.1
Xu, S.2
Li, W.3
-
27
-
-
84901620231
-
Sedum sarmentosum Bunge extract exerts renal anti-fibrotic effects in vivo and in vitro
-
Bai Y, Lu H, Zhang G, et al. Sedum sarmentosum Bunge extract exerts renal anti-fibrotic effects in vivo and in vitro. Life Sci. 2014; 105: 22-30.
-
(2014)
Life Sci
, vol.105
, pp. 22-30
-
-
Bai, Y.1
Lu, H.2
Zhang, G.3
-
28
-
-
80055113845
-
CCND1 as a predictive biomarker of neoadjuvant chemotherapy in patients with locally advanced head and neck squamous cell carcinoma
-
Feng Z, Guo W, Zhang C, et al. CCND1 as a predictive biomarker of neoadjuvant chemotherapy in patients with locally advanced head and neck squamous cell carcinoma. PLoS ONE. 2011; 6: e26399.
-
(2011)
PLoS ONE
, vol.6
, pp. e26399
-
-
Feng, Z.1
Guo, W.2
Zhang, C.3
-
29
-
-
84925439755
-
Altered localization of p120 catenin in the cytoplasm rather than the membrane correlates with poor prognosis in esophageal squamous cell carcinoma
-
Chen T, Wang C, Wu F, et al. Altered localization of p120 catenin in the cytoplasm rather than the membrane correlates with poor prognosis in esophageal squamous cell carcinoma. PLoS ONE. 2015; 10: e0118645.
-
(2015)
PLoS ONE
, vol.10
, pp. e0118645
-
-
Chen, T.1
Wang, C.2
Wu, F.3
-
30
-
-
84910634437
-
Resveratrol inhibits epithelial-mesenchymal transition and renal fibrosis by antagonizing the hedgehog signaling pathway
-
Bai Y, Lu H, Wu C, et al. Resveratrol inhibits epithelial-mesenchymal transition and renal fibrosis by antagonizing the hedgehog signaling pathway. Biochem Pharmacol. 2014; 92: 484-93.
-
(2014)
Biochem Pharmacol
, vol.92
, pp. 484-493
-
-
Bai, Y.1
Lu, H.2
Wu, C.3
-
31
-
-
79955654219
-
OxLDL up-regulates microRNA-29b, leading to epigenetic modifications of MMP-2/MMP-9 genes: a novel mechanism for cardiovascular diseases
-
Chen KC, Wang YS, Hu CY, et al. OxLDL up-regulates microRNA-29b, leading to epigenetic modifications of MMP-2/MMP-9 genes: a novel mechanism for cardiovascular diseases. FASEB J. 2011; 25: 1718-28.
-
(2011)
FASEB J
, vol.25
, pp. 1718-1728
-
-
Chen, K.C.1
Wang, Y.S.2
Hu, C.Y.3
-
32
-
-
44949231424
-
Analyzing real-time PCR data by the comparative C(T) method
-
Schmittgen TD, Livak KJ. Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc. 2008; 3: 1101-8.
-
(2008)
Nat Protoc
, vol.3
, pp. 1101-1108
-
-
Schmittgen, T.D.1
Livak, K.J.2
-
33
-
-
46949093531
-
Epigenetic silencing of O6-methylguanine DNA methyltransferase gene in NiS-transformed cells
-
Ji W, Yang L, Yu L, et al. Epigenetic silencing of O6-methylguanine DNA methyltransferase gene in NiS-transformed cells. Carcinogenesis. 2008; 29: 1267-75.
-
(2008)
Carcinogenesis
, vol.29
, pp. 1267-1275
-
-
Ji, W.1
Yang, L.2
Yu, L.3
-
34
-
-
55849135600
-
Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans
-
Omenetti A, Porrello A, Jung Y, et al. Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans. J Clin Invest. 2008; 118: 3331-42.
-
(2008)
J Clin Invest
, vol.118
, pp. 3331-3342
-
-
Omenetti, A.1
Porrello, A.2
Jung, Y.3
-
35
-
-
27144554034
-
Role for hedgehog signaling in hepatic stellate cell activation and viability
-
Sicklick JK, Li YX, Choi SS, et al. Role for hedgehog signaling in hepatic stellate cell activation and viability. Lab Invest. 2005; 85: 1368-80.
-
(2005)
Lab Invest
, vol.85
, pp. 1368-1380
-
-
Sicklick, J.K.1
Li, Y.X.2
Choi, S.S.3
-
36
-
-
36549011761
-
Sonic hedgehog is an autocrine viability factor for myofibroblastic hepatic stellate cells
-
Yang L, Wang Y, Mao H, et al. Sonic hedgehog is an autocrine viability factor for myofibroblastic hepatic stellate cells. J Hepatol. 2008; 48: 98-106.
-
(2008)
J Hepatol
, vol.48
, pp. 98-106
-
-
Yang, L.1
Wang, Y.2
Mao, H.3
-
37
-
-
84871423288
-
Salvianolic acid B attenuates rat hepatic fibrosis via downregulating angiotensin II signaling
-
Li S, Wang L, Yan X, et al. Salvianolic acid B attenuates rat hepatic fibrosis via downregulating angiotensin II signaling. Evid Based Complement Alternat Med. 2012; 2012: 160726.
-
(2012)
Evid Based Complement Alternat Med
, vol.2012
, pp. 160726
-
-
Li, S.1
Wang, L.2
Yan, X.3
-
38
-
-
77951777413
-
Salvianolic acid B prevents epithelial-to-mesenchymal transition through the TGF-beta1 signal transduction pathway in vivo and in vitro
-
Wang QL, Tao YY, Yuan JL, et al. Salvianolic acid B prevents epithelial-to-mesenchymal transition through the TGF-beta1 signal transduction pathway in vivo and in vitro. BMC Cell Biol. 2010; 11: 31.
-
(2010)
BMC Cell Biol
, vol.11
, pp. 31
-
-
Wang, Q.L.1
Tao, Y.Y.2
Yuan, J.L.3
-
39
-
-
84925466770
-
Mir-152 inhibits cell proliferation and colony formation of CD133(+) liver cancer stem cells by targeting KIT
-
Huang H, Hu M, Li P, et al. Mir-152 inhibits cell proliferation and colony formation of CD133(+) liver cancer stem cells by targeting KIT. Tumour Biol. 2015; 36: 921-8.
-
(2015)
Tumour Biol
, vol.36
, pp. 921-928
-
-
Huang, H.1
Hu, M.2
Li, P.3
-
40
-
-
84897499643
-
HCV core protein-induced down-regulation of microRNA-152 promoted aberrant proliferation by regulating Wnt1 in HepG2 cells
-
Huang S, Xie Y, Yang P, et al. HCV core protein-induced down-regulation of microRNA-152 promoted aberrant proliferation by regulating Wnt1 in HepG2 cells. PLoS ONE. 2014; 9: e81730.
-
(2014)
PLoS ONE
, vol.9
, pp. e81730
-
-
Huang, S.1
Xie, Y.2
Yang, P.3
|