메뉴 건너뛰기




Volumn 2016, Issue , 2016, Pages

Biology of Beige Adipocyte and Possible Therapy for Type 2 Diabetes and Obesity

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; MICRORNA; THYROID HORMONE;

EID: 84982105808     PISSN: 16878337     EISSN: 16878345     Source Type: Journal    
DOI: 10.1155/2016/9542061     Document Type: Review
Times cited : (31)

References (123)
  • 1
    • 84924288618 scopus 로고    scopus 로고
    • Treatment-dependent and treatment-independent risk factors associated with the risk of diabetes-related events: A retrospective analysis based on 229, 042 patients with type 2 diabetes mellitus
    • T. Wilke, S. Mueller, A. Groth et al., "Treatment-dependent and treatment-independent risk factors associated with the risk of diabetes-related events: a retrospective analysis based on 229, 042 patients with type 2 diabetes mellitus, " Cardiovascular Diabetology, vol. 14, no. 1, article 14, 2015.
    • (2015) Cardiovascular Diabetology , vol.14 , Issue.1
    • Wilke, T.1    Mueller, S.2    Groth, A.3
  • 2
    • 84898540957 scopus 로고    scopus 로고
    • Global guideline for type 2 diabetes
    • International Diabetes Federation Guideline Development Group
    • International Diabetes Federation Guideline Development Group, "Global guideline for type 2 diabetes, " Diabetes Research and Clinical Practice, vol. 104, no. 1, pp. 1-52, 2014.
    • (2014) Diabetes Research and Clinical Practice , vol.104 , Issue.1 , pp. 1-52
  • 4
    • 84883318855 scopus 로고    scopus 로고
    • Behavioral and dietary risk factors for noncommunicable diseases
    • M. Ezzati and E. Riboli, "Behavioral and dietary risk factors for noncommunicable diseases, " The New England Journal of Medicine, vol. 369, no. 10, pp. 954-964, 2013.
    • (2013) The New England Journal of Medicine , vol.369 , Issue.10 , pp. 954-964
    • Ezzati, M.1    Riboli, E.2
  • 6
    • 84943358575 scopus 로고    scopus 로고
    • The current drug treatment landscape for diabetes and perspectives for the future
    • C. J. Bailey, "The current drug treatment landscape for diabetes and perspectives for the future, " Clinical Pharmacology and Therapeutics, vol. 98, no. 2, pp. 170-184, 2015.
    • (2015) Clinical Pharmacology and Therapeutics , vol.98 , Issue.2 , pp. 170-184
    • Bailey, C.J.1
  • 8
    • 84949571165 scopus 로고    scopus 로고
    • European guidelines for obesity management in adults
    • V. Yumuk, C. Tsigos, M. Fried et al., "European guidelines for obesity management in adults, " Obesity Facts, vol. 8, no. 6, pp. 402-424, 2015.
    • (2015) Obesity Facts , vol.8 , Issue.6 , pp. 402-424
    • Yumuk, V.1    Tsigos, C.2    Fried, M.3
  • 9
    • 84937413016 scopus 로고    scopus 로고
    • Treatment of obesity: Pharmacotherapy trends in the United States from 1999 to 2010
    • Y. Xia, C. M. L. Kelton, J. J. Guo, B. Bian, and P. C. Heaton, "Treatment of obesity: pharmacotherapy trends in the United States from 1999 to 2010, " Obesity, vol. 23, no. 8, pp. 1721-1728, 2015.
    • (2015) Obesity , vol.23 , Issue.8 , pp. 1721-1728
    • Xia, Y.1    Kelton, C.M.L.2    Guo, J.J.3    Bian, B.4    Heaton, P.C.5
  • 10
    • 84922570654 scopus 로고    scopus 로고
    • Pharmacological management of obesity: An endocrine society clinical practice guideline
    • C. M. Apovian, L. J. Aronne, D. H. Bessesen et al., "Pharmacological management of obesity: an endocrine society clinical practice guideline, " Journal of Clinical Endocrinology and Metabolism, vol. 100, no. 2, pp. 342-362, 2015.
    • (2015) Journal of Clinical Endocrinology and Metabolism , vol.100 , Issue.2 , pp. 342-362
    • Apovian, C.M.1    Aronne, L.J.2    Bessesen, D.H.3
  • 11
    • 84964841784 scopus 로고    scopus 로고
    • Regulation of human subcutaneous adipocyte differentiation by EID1
    • D. Vargas, N. Shimokawa, R. Kaneko et al., "Regulation of human subcutaneous adipocyte differentiation by EID1, " Journal of Molecular Endocrinology, vol. 56, no. 2, pp. 113-122, 2016.
    • (2016) Journal of Molecular Endocrinology , vol.56 , Issue.2 , pp. 113-122
    • Vargas, D.1    Shimokawa, N.2    Kaneko, R.3
  • 12
    • 84962076500 scopus 로고    scopus 로고
    • Brown and beige fat: Molecular parts of a thermogenic machine
    • P. Cohen and B. M. Spiegelman, "Brown and beige fat: molecular parts of a thermogenic machine, " Diabetes, vol. 64, no. 7, pp. 2346-2351, 2015.
    • (2015) Diabetes , vol.64 , Issue.7 , pp. 2346-2351
    • Cohen, P.1    Spiegelman, B.M.2
  • 13
    • 84892727198 scopus 로고    scopus 로고
    • What we talk about when we talk about fat
    • E. D. Rosen and B. M. Spiegelman, "What we talk about when we talk about fat, " Cell, vol. 156, no. 1-2, pp. 20-44, 2014.
    • (2014) Cell , vol.156 , Issue.1-2 , pp. 20-44
    • Rosen, E.D.1    Spiegelman, B.M.2
  • 15
    • 84873518501 scopus 로고    scopus 로고
    • Adaptive thermogenesis in adipocytes: Is beige the newbrown
    • J. Wu, P. Cohen, andB. M. Spiegelman, "Adaptive thermogenesis in adipocytes: is beige the newbrown"Genes andDevelopment, vol. 27, no. 3, pp. 234-250, 2013.
    • (2013) Genes AndDevelopment , vol.27 , Issue.3 , pp. 234-250
    • Wu, J.1    Cohen, P.2    Spiegelman, B.M.3
  • 16
    • 84943402947 scopus 로고    scopus 로고
    • Brown and beige fat: Physiological roles beyond heat generation
    • S. Kajimura, B. M. Spiegelman, and P. Seale, "Brown and beige fat: physiological roles beyond heat generation, " Cell Metabolism, vol. 22, no. 4, pp. 546-559, 2015.
    • (2015) Cell Metabolism , vol.22 , Issue.4 , pp. 546-559
    • Kajimura, S.1    Spiegelman, B.M.2    Seale, P.3
  • 17
    • 84864287504 scopus 로고    scopus 로고
    • Beige adipocytes are a distinct typeof thermogenic fat cell inmouse andhuman
    • J. Wu, P. Boström, L. M. Sparks et al., "Beige adipocytes are a distinct typeof thermogenic fat cell inmouse andhuman, " Cell, vol. 150, no. 2, pp. 366-376, 2012.
    • (2012) Cell , vol.150 , Issue.2 , pp. 366-376
    • Wu, J.1    Boström, P.2    Sparks, L.M.3
  • 18
    • 84920940721 scopus 로고    scopus 로고
    • Activated type 2 innate lymphoid cells regulate beige fat biogenesis
    • M.-W. Lee, J. I. Odegaard, L. Mukundan et al., "Activated type 2 innate lymphoid cells regulate beige fat biogenesis, " Cell, vol. 160, no. 1-2, pp. 74-87, 2015.
    • (2015) Cell , vol.160 , Issue.1-2 , pp. 74-87
    • Lee, M.-W.1    Odegaard, J.I.2    Mukundan, L.3
  • 20
    • 84887431711 scopus 로고    scopus 로고
    • Brown and beige fat: Development, function and therapeutic potential
    • M. Harms and P. Seale, "Brown and beige fat: development, function and therapeutic potential, " Nature Medicine, vol. 19, no. 10, pp. 1252-1263, 2013.
    • (2013) Nature Medicine , vol.19 , Issue.10 , pp. 1252-1263
    • Harms, M.1    Seale, P.2
  • 21
    • 84892702771 scopus 로고    scopus 로고
    • Ablation of PRDM16 and beige adipose causesmetabolic dysfunction and a subcutaneous to visceral fat switch
    • P. Cohen, J. D. Levy, Y. Zhang et al., "Ablation of PRDM16 and beige adipose causesmetabolic dysfunction and a subcutaneous to visceral fat switch, " Cell, vol. 156, no. 1-2, pp. 304-316, 2014.
    • (2014) Cell , vol.156 , Issue.1-2 , pp. 304-316
    • Cohen, P.1    Levy, J.D.2    Zhang, Y.3
  • 22
    • 50049122271 scopus 로고    scopus 로고
    • PRDM16 controls a brown fat/skeletal muscle switch
    • P. Seale, B. Bjork, W. Yang et al., "PRDM16 controls a brown fat/skeletal muscle switch, " Nature, vol. 454, no. 7207, pp. 961-967, 2008.
    • (2008) Nature , vol.454 , Issue.7207 , pp. 961-967
    • Seale, P.1    Bjork, B.2    Yang, W.3
  • 23
    • 84935855975 scopus 로고    scopus 로고
    • Shades of brown: A model for thermogenic fat
    • J. Dempersmier and H. S. Sul, "Shades of brown: a model for thermogenic fat, " Frontiers in Endocrinology, vol. 6, article 71, 2015.
    • (2015) Frontiers in Endocrinology , vol.6
    • Dempersmier, J.1    Sul, H.S.2
  • 24
    • 84896710569 scopus 로고    scopus 로고
    • Functional thermogenic beige adipogenesis is inducible in human neck fat
    • P. Lee, C. D. Werner, E. Kebebew, and F. S. Celi, "Functional thermogenic beige adipogenesis is inducible in human neck fat, " International Journal of Obesity, vol. 38, no. 2, pp. 170-176, 2014.
    • (2014) International Journal of Obesity , vol.38 , Issue.2 , pp. 170-176
    • Lee, P.1    Werner, C.D.2    Kebebew, E.3    Celi, F.S.4
  • 25
    • 84880652296 scopus 로고    scopus 로고
    • Inducible brown adipose tissue, or beige fat, is anabolic for the skeleton
    • S. Rahman, Y. Lu, P. J. Czernik, C. J. Rosen, S. Enerback, and B. Lecka-Czernik, "Inducible brown adipose tissue, or beige fat, is anabolic for the skeleton, " Endocrinology, vol. 154, no. 8, pp. 2687-2701, 2013.
    • (2013) Endocrinology , vol.154 , Issue.8 , pp. 2687-2701
    • Rahman, S.1    Lu, Y.2    Czernik, P.J.3    Rosen, C.J.4    Enerback, S.5    Lecka-Czernik, B.6
  • 26
    • 84958108874 scopus 로고    scopus 로고
    • Epigenetics: On-off switch for obesity
    • D. Holmes, "Epigenetics: on-off switch for obesity, " Nature Reviews Endocrinology, vol. 12, no. 3, p. 125, 2016.
    • (2016) Nature Reviews Endocrinology , vol.12 , Issue.3 , pp. 125
    • Holmes, D.1
  • 27
    • 85013142423 scopus 로고    scopus 로고
    • Engineering fat cell fate to fight obesity and metabolic diseases
    • S. Kajimura, "Engineering fat cell fate to fight obesity and metabolic diseases, " The Keio Journal of Medicine, vol. 64, no. 4, p. 65, 2015.
    • (2015) The Keio Journal of Medicine , vol.64 , Issue.4 , pp. 65
    • Kajimura, S.1
  • 28
    • 84955587698 scopus 로고    scopus 로고
    • Human 'brite/beige' adipocytes develop from capillary networks, and their implantation improves metabolic homeostasis in mice
    • S. Y. Min, J. Kady, M. Nam et al., "Human 'brite/beige' adipocytes develop from capillary networks, and their implantation improves metabolic homeostasis in mice, " Nature Medicine, vol. 22, pp. 312-318, 2016.
    • (2016) Nature Medicine , vol.22 , pp. 312-318
    • Min, S.Y.1    Kady, J.2    Nam, M.3
  • 30
    • 84881259220 scopus 로고    scopus 로고
    • Distinct populations of adipogenic and myogenicMyf5-lineage progenitors in white adipose tissues
    • T. Shan, X. Liang, P. Bi, P. Zhang, W. Liu, and S. Kuang, "Distinct populations of adipogenic and myogenicMyf5-lineage progenitors in white adipose tissues, " Journal of Lipid Research, vol. 54, no. 8, pp. 2214-2224, 2013.
    • (2013) Journal of Lipid Research , vol.54 , Issue.8 , pp. 2214-2224
    • Shan, T.1    Liang, X.2    Bi, P.3    Zhang, P.4    Liu, W.5    Kuang, S.6
  • 32
    • 84883354892 scopus 로고    scopus 로고
    • A heterogeneous lineage origin underlies the phenotypic and molecular differences of white and beige adipocytes
    • W. Liu, T. Shan, X. Yang et al., "A heterogeneous lineage origin underlies the phenotypic and molecular differences of white and beige adipocytes, " Journal of Cell Science, vol. 126, no. 16, pp. 3527-3532, 2013.
    • (2013) Journal of Cell Science , vol.126 , Issue.16 , pp. 3527-3532
    • Liu, W.1    Shan, T.2    Yang, X.3
  • 33
    • 84865792944 scopus 로고    scopus 로고
    • PTEN loss in the Myf5 lineage redistributes body fat and reveals subsets of white adipocytes that arise from Myf5 precursors
    • J. Sanchez-Gurmaches, C.-M. Hung, C. A. Sparks, Y. Tang, H. Li, and D. A. Guertin, "PTEN loss in the Myf5 lineage redistributes body fat and reveals subsets of white adipocytes that arise from Myf5 precursors, " Cell Metabolism, vol. 16, no. 3, pp. 348-362, 2012.
    • (2012) Cell Metabolism , vol.16 , Issue.3 , pp. 348-362
    • Sanchez-Gurmaches, J.1    Hung, C.-M.2    Sparks, C.A.3    Tang, Y.4    Li, H.5    Guertin, D.A.6
  • 34
    • 84859465056 scopus 로고    scopus 로고
    • In vivo identification of bipotential adipocyte progenitors recruited by 3-adrenoceptor activation and high-fat feeding
    • Y.-H. Lee, A. P. Petkova, E. P. Mottillo, and J. G. Granneman, "In vivo identification of bipotential adipocyte progenitors recruited by 3-adrenoceptor activation and high-fat feeding, " Cell Metabolism, vol. 15, no. 4, pp. 480-491, 2012.
    • (2012) Cell Metabolism , vol.15 , Issue.4 , pp. 480-491
    • Lee, Y.-H.1    Petkova, A.P.2    Mottillo, E.P.3    Granneman, J.G.4
  • 35
    • 84900325394 scopus 로고    scopus 로고
    • A smooth muscle-like origin for beige adipocytes
    • J. Z. Long, K. J. Svensson, L. Tsai et al., "A smooth muscle-like origin for beige adipocytes, " Cell Metabolism, vol. 19, no. 5, pp. 810-820, 2014.
    • (2014) Cell Metabolism , vol.19 , Issue.5 , pp. 810-820
    • Long, J.Z.1    Svensson, K.J.2    Tsai, L.3
  • 36
    • 77952623888 scopus 로고    scopus 로고
    • The emergence of cold-induced brown adipocytes in mouse white fat depots is determined predominantly by white to brown adipocyte transdifferentiation
    • G. Barbatelli, I. Murano, L. Madsen et al., "The emergence of cold-induced brown adipocytes in mouse white fat depots is determined predominantly by white to brown adipocyte transdifferentiation, " American Journal of Physiology-Endocrinology and Metabolism, vol. 298, no. 6, pp. E1244-E1253, 2010.
    • (2010) American Journal of Physiology-Endocrinology and Metabolism , vol.298 , Issue.6 , pp. E1244-E1253
    • Barbatelli, G.1    Murano, I.2    Madsen, L.3
  • 37
    • 84878525220 scopus 로고    scopus 로고
    • Bi-directional interconversion of brite and white adipocytes
    • M. Rosenwald, A. Perdikari, T. Rülicke, and C. Wolfrum, "Bi-directional interconversion of brite and white adipocytes, " Nature Cell Biology, vol. 15, no. 6, pp. 659-667, 2013.
    • (2013) Nature Cell Biology , vol.15 , Issue.6 , pp. 659-667
    • Rosenwald, M.1    Perdikari, A.2    Rülicke, T.3    Wolfrum, C.4
  • 38
    • 84893748960 scopus 로고    scopus 로고
    • Regenerative medicine: Transdifferentiation in vivo
    • L. Fu, X. Zhu, F. Yi, G.-H. Liu, and J. C. Izpisua Belmonte, "Regenerative medicine: transdifferentiation in vivo, " Cell Research, vol. 24, no. 2, pp. 141-142, 2014.
    • (2014) Cell Research , vol.24 , Issue.2 , pp. 141-142
    • Fu, L.1    Zhu, X.2    Yi, F.3    Liu, G.-H.4    Izpisua Belmonte, J.C.5
  • 39
    • 84904636950 scopus 로고    scopus 로고
    • The origin and definition of brite versus white and classical brown adipocytes
    • M. Rosenwald and C. Wolfrum, "The origin and definition of brite versus white and classical brown adipocytes, " Adipocyte, vol. 3, no. 1, pp. 4-9, 2014.
    • (2014) Adipocyte , vol.3 , Issue.1 , pp. 4-9
    • Rosenwald, M.1    Wolfrum, C.2
  • 40
    • 84949863726 scopus 로고    scopus 로고
    • Transcriptional regulatory circuits controlling brown fat development and activation
    • P. Seale, "Transcriptional regulatory circuits controlling brown fat development and activation, " Diabetes, vol. 64, no. 7, pp. 2369-2375, 2015.
    • (2015) Diabetes , vol.64 , Issue.7 , pp. 2369-2375
    • Seale, P.1
  • 41
    • 84928766717 scopus 로고    scopus 로고
    • Formation and activation of thermogenic fat
    • J. Wu, H. Jun, and J. R. McDermott, "Formation and activation of thermogenic fat, " Trends in Genetics, vol. 31, no. 5, pp. 232-238, 2015.
    • (2015) Trends in Genetics , vol.31 , Issue.5 , pp. 232-238
    • Wu, J.1    Jun, H.2    McDermott, J.R.3
  • 42
    • 84922335288 scopus 로고    scopus 로고
    • Thermogenic activity of UCP1 in human white fat-derived beige adipocytes
    • S. Bartesaghi, S. Hallen, L. Huang et al., "Thermogenic activity of UCP1 in human white fat-derived beige adipocytes, " Molecular Endocrinology, vol. 29, no. 1, pp. 130-139, 2015.
    • (2015) Molecular Endocrinology , vol.29 , Issue.1 , pp. 130-139
    • Bartesaghi, S.1    Hallen, S.2    Huang, L.3
  • 43
    • 84954536294 scopus 로고    scopus 로고
    • Brown and beige fat: The metabolic function, induction, and therapeutic potential
    • S. Qian, H. Huang, and Q. Tang, "Brown and beige fat: the metabolic function, induction, and therapeutic potential, " Frontiers of Medicine, vol. 9, no. 2, pp. 162-172, 2015.
    • (2015) Frontiers of Medicine , vol.9 , Issue.2 , pp. 162-172
    • Qian, S.1    Huang, H.2    Tang, Q.3
  • 44
    • 84874413612 scopus 로고    scopus 로고
    • Adrenoceptor signaling networks in adipocytes for recruiting stored fat and energy expenditure
    • S. Collins, "-Adrenoceptor signaling networks in adipocytes for recruiting stored fat and energy expenditure, " Frontiers in Endocrinology, vol. 2, article 102, 2012.
    • (2012) Frontiers in Endocrinology , vol.2
    • Collins, S.1
  • 45
    • 58149337340 scopus 로고    scopus 로고
    • Noradrenergic parenchymal nerve fiber branching after cold acclimatisation correlates with brown adipocyte density in mouse adipose organ
    • I. Murano, G. Barbatelli, A. Giordano, and S. Cinti, "Noradrenergic parenchymal nerve fiber branching after cold acclimatisation correlates with brown adipocyte density in mouse adipose organ, " Journal of Anatomy, vol. 214, no. 1, pp. 171-178, 2009.
    • (2009) Journal of Anatomy , vol.214 , Issue.1 , pp. 171-178
    • Murano, I.1    Barbatelli, G.2    Giordano, A.3    Cinti, S.4
  • 46
    • 84902094655 scopus 로고    scopus 로고
    • Eosinophils and type 2 cytokine signaling in macrophages orchestrate development of functional beige fat
    • Y. Qiu, K. D. Nguyen, J. I. Odegaard et al., "Eosinophils and type 2 cytokine signaling in macrophages orchestrate development of functional beige fat, " Cell, vol. 157, no. 6, pp. 1292-1308, 2014.
    • (2014) Cell , vol.157 , Issue.6 , pp. 1292-1308
    • Qiu, Y.1    Nguyen, K.D.2    Odegaard, J.I.3
  • 47
    • 84924969384 scopus 로고    scopus 로고
    • Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity
    • J. R. Brestoff, B. S. Kim, S. A. Saenz et al., "Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity, " Nature, vol. 519, no. 7542, pp. 242-246, 2015.
    • (2015) Nature , vol.519 , Issue.7542 , pp. 242-246
    • Brestoff, J.R.1    Kim, B.S.2    Saenz, S.A.3
  • 48
    • 84939864079 scopus 로고    scopus 로고
    • Modifications of human subcutaneous ADMSC after PPAR activation and cold exposition
    • D. Vargas, W. Rosales, and F. Lizcano, "Modifications of human subcutaneous ADMSC after PPAR activation and cold exposition, " Stem Cells International, vol. 2015, Article ID 196348, 8 pages, 2015.
    • (2015) Stem Cells International , vol.2015
    • Vargas, D.1    Rosales, W.2    Lizcano, F.3
  • 49
    • 80052739107 scopus 로고    scopus 로고
    • White to brown fat phenotypic switch induced by genetic and environmental activation of a hypothalamic-adipocyte axis
    • L. Cao, E. Y. Choi, X. Liu et al., "White to brown fat phenotypic switch induced by genetic and environmental activation of a hypothalamic-adipocyte axis, " CellMetabolism, vol. 14, no. 3, pp. 324-338, 2011.
    • (2011) CellMetabolism , vol.14 , Issue.3 , pp. 324-338
    • Cao, L.1    Choi, E.Y.2    Liu, X.3
  • 50
    • 84960538964 scopus 로고    scopus 로고
    • Role of hypothalamic VGF in energy balance andmetabolic adaption to environmental enrichment in mice
    • G. D. Foglesong, W. Huang, X. Liu et al., "Role of hypothalamic VGF in energy balance andmetabolic adaption to environmental enrichment in mice, " Endocrinology, vol. 157, no. 3, pp. 983-996, 2016.
    • (2016) Endocrinology , vol.157 , Issue.3 , pp. 983-996
    • Foglesong, G.D.1    Huang, W.2    Liu, X.3
  • 51
    • 84857784321 scopus 로고    scopus 로고
    • TRPV1 activation improves exercise endurance and energy metabolism through PGC-1 upregulation in mice
    • Z. Luo, L. Ma, Z. Zhao et al., "TRPV1 activation improves exercise endurance and energy metabolism through PGC-1 upregulation in mice, " Cell Research, vol. 22, no. 3, pp. 551-564, 2012.
    • (2012) Cell Research , vol.22 , Issue.3 , pp. 551-564
    • Luo, Z.1    Ma, L.2    Zhao, Z.3
  • 52
    • 84862776702 scopus 로고    scopus 로고
    • A PGC1-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
    • P. Boström, J. Wu, M. P. Jedrychowski et al., "A PGC1-dependent myokine that drives brown-fat-like development of white fat and thermogenesis, " Nature, vol. 481, no. 7382, pp. 463-468, 2012.
    • (2012) Nature , vol.481 , Issue.7382 , pp. 463-468
    • Boström, P.1    Wu, J.2    Jedrychowski, M.P.3
  • 53
    • 84891840977 scopus 로고    scopus 로고
    • Aminoisobutyric acid induces browning ofwhite fat and hepatic-oxidation and is inversely correlated with cardiometabolic risk factors
    • L. D. Roberts, P. Boström, J. F. O'Sullivanet al., "-Aminoisobutyric acid induces browning ofwhite fat and hepatic-oxidation and is inversely correlated with cardiometabolic risk factors, " Cell Metabolism, vol. 19, no. 1, pp. 96-108, 2014.
    • (2014) Cell Metabolism , vol.19 , Issue.1 , pp. 96-108
    • Roberts, L.D.1    Boström, P.2    O'Sullivan, J.F.3
  • 54
    • 84943451163 scopus 로고    scopus 로고
    • Detection and quantitation of circulating human irisin by tandem mass spectrometry
    • M. P. Jedrychowski, C. D. Wrann, J. A. Paulo et al., "Detection and quantitation of circulating human irisin by tandem mass spectrometry, " CellMetabolism, vol. 22, no. 4, pp. 734-740, 2015.
    • (2015) CellMetabolism , vol.22 , Issue.4 , pp. 734-740
    • Jedrychowski, M.P.1    Wrann, C.D.2    Paulo, J.A.3
  • 55
    • 84895086158 scopus 로고    scopus 로고
    • The effects of acute and chronic exercise on PGC-1, irisin and browning of subcutaneous adipose tissue in humans
    • F. Norheim, T. M. Langleite, M. Hjorth et al., "The effects of acute and chronic exercise on PGC-1, irisin and browning of subcutaneous adipose tissue in humans, "The FEBS Journal, vol. 281, no. 3, pp. 739-749, 2014.
    • (2014) The FEBS Journal , vol.281 , Issue.3 , pp. 739-749
    • Norheim, F.1    Langleite, T.M.2    Hjorth, M.3
  • 56
    • 84925018403 scopus 로고    scopus 로고
    • Irisin stimulates muscle growth-related genes and regulates adipocyte differentiation and metabolism in humans
    • J. Y. Huh, F. Dincer, E. Mesfum, and C. S. Mantzoros, "Irisin stimulates muscle growth-related genes and regulates adipocyte differentiation and metabolism in humans, " International Journal of Obesity, vol. 38, no. 12, pp. 1538-1544, 2014.
    • (2014) International Journal of Obesity , vol.38 , Issue.12 , pp. 1538-1544
    • Huh, J.Y.1    Dincer, F.2    Mesfum, E.3    Mantzoros, C.S.4
  • 57
    • 84902097377 scopus 로고    scopus 로고
    • Meteorin-like is a hormone that regulates immune-adipose interactions to increase beige fat thermogenesis
    • R. R. Rao, J. Z. Long, J. P. White et al., "Meteorin-like is a hormone that regulates immune-adipose interactions to increase beige fat thermogenesis, " Cell, vol. 157, no. 6, pp. 1279-1291, 2014.
    • (2014) Cell , vol.157 , Issue.6 , pp. 1279-1291
    • Rao, R.R.1    Long, J.Z.2    White, J.P.3
  • 58
    • 84949626813 scopus 로고    scopus 로고
    • Low brown adipose tissue activity in endurance-trained compared with lean sedentary men
    • M. J. Vosselman, J. Hoeks, B. Brans et al., "Low brown adipose tissue activity in endurance-trained compared with lean sedentary men, " International Journal of Obesity, vol. 39, no. 12, pp. 1696-1702, 2015.
    • (2015) International Journal of Obesity , vol.39 , Issue.12 , pp. 1696-1702
    • Vosselman, M.J.1    Hoeks, J.2    Brans, B.3
  • 59
    • 84907485620 scopus 로고    scopus 로고
    • Browning of white adipose cells by intermediate metabolites: An adaptive mechanismto alleviate redox pressure
    • A. Carrière, Y. Jeanson, S. Berger-Müller et al., "Browning of white adipose cells by intermediate metabolites: an adaptive mechanismto alleviate redox pressure, " Diabetes, vol. 63, no. 10, pp. 3253-3265, 2014.
    • (2014) Diabetes , vol.63 , Issue.10 , pp. 3253-3265
    • Carrière, A.1    Jeanson, Y.2    Berger-Müller, S.3
  • 60
    • 84947330563 scopus 로고    scopus 로고
    • Human adipocytes induce inflammation and atrophy in muscle cells during obesity
    • V. Pellegrinelli, C. Rouault, S. Rodriguez-Cuenca et al., "Human adipocytes induce inflammation and atrophy in muscle cells during obesity, " Diabetes, vol. 64, no. 9, pp. 3121-3134, 2015.
    • (2015) Diabetes , vol.64 , Issue.9 , pp. 3121-3134
    • Pellegrinelli, V.1    Rouault, C.2    Rodriguez-Cuenca, S.3
  • 61
    • 84907279764 scopus 로고    scopus 로고
    • Knock-down of IL-1Ra in obese mice decreases liver inflammation and improves insulin sensitivity
    • N. Franck, M. Maris, S. Nalbandian et al., "Knock-down of IL-1Ra in obese mice decreases liver inflammation and improves insulin sensitivity, " PLoS ONE, vol. 9, no. 9, Article ID e107487, 2014.
    • (2014) PLoS ONE , vol.9 , Issue.9
    • Franck, N.1    Maris, M.2    Nalbandian, S.3
  • 62
    • 84962483123 scopus 로고    scopus 로고
    • The role of gp130 receptor cytokines in the regulation of metabolic homeostasis
    • L. Cron, T. Allen, and M. A. Febbraio, "The role of gp130 receptor cytokines in the regulation of metabolic homeostasis, " Journal of Experimental Biology, vol. 219, part 2, pp. 259-265, 2016.
    • (2016) Journal of Experimental Biology , vol.219 , pp. 259-265
    • Cron, L.1    Allen, T.2    Febbraio, M.A.3
  • 63
    • 34547106324 scopus 로고    scopus 로고
    • Tumor necrosis factor (TNF) stimulates Map4k4 expression through TNF receptor 1 signaling to c-Jun and activating transcription factor 2
    • G. J. Tesz, A. Guilherme, K. V. P. Guntur et al., "Tumor necrosis factor (TNF) stimulates Map4k4 expression through TNF receptor 1 signaling to c-Jun and activating transcription factor 2, " The Journal of Biological Chemistry, vol. 282, no. 27, pp. 19302-19312, 2007.
    • (2007) The Journal of Biological Chemistry , vol.282 , Issue.27 , pp. 19302-19312
    • Tesz, G.J.1    Guilherme, A.2    Guntur, K.V.P.3
  • 64
    • 82555186955 scopus 로고    scopus 로고
    • Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis
    • K. D. Nguyen, Y. Qiu, X. Cui et al., "Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis, " Nature, vol. 480, no. 7375, pp. 104-108, 2011.
    • (2011) Nature , vol.480 , Issue.7375 , pp. 104-108
    • Nguyen, K.D.1    Qiu, Y.2    Cui, X.3
  • 65
    • 84889667457 scopus 로고    scopus 로고
    • Adipose tissue macrophages: Amicus adipem
    • J. I. Odegaard, K. Ganeshan, and A. Chawla, "Adipose tissue macrophages: Amicus adipem" Cell Metabolism, vol. 18, no. 6, pp. 767-768, 2013.
    • (2013) Cell Metabolism , vol.18 , Issue.6 , pp. 767-768
    • Odegaard, J.I.1    Ganeshan, K.2    Chawla, A.3
  • 66
    • 84876274371 scopus 로고    scopus 로고
    • Type 2 innate signals stimulate fibro/adipogenic progenitors to facilitate muscle regeneration
    • J. E. Heredia, L. Mukundan, F. M. Chen et al., "Type 2 innate signals stimulate fibro/adipogenic progenitors to facilitate muscle regeneration, " Cell, vol. 153, no. 2, pp. 376-388, 2013.
    • (2013) Cell , vol.153 , Issue.2 , pp. 376-388
    • Heredia, J.E.1    Mukundan, L.2    Chen, F.M.3
  • 67
    • 84876746655 scopus 로고    scopus 로고
    • Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages
    • A. B. Molofsky, J. C. Nussbaum, H.-E. Liang et al., "Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages, " The Journal of Experimental Medicine, vol. 210, no. 3, pp. 535-549, 2013.
    • (2013) The Journal of Experimental Medicine , vol.210 , Issue.3 , pp. 535-549
    • Molofsky, A.B.1    Nussbaum, J.C.2    Liang, H.-E.3
  • 68
    • 84904725741 scopus 로고    scopus 로고
    • Metabolism: Type 2 immunity at the origin of beige adipocytes
    • J. Osório, "Metabolism: type 2 immunity at the origin of beige adipocytes, " Nature Reviews Endocrinology, vol. 10, no. 8, p. 443, 2014.
    • (2014) Nature Reviews Endocrinology , vol.10 , Issue.8 , pp. 443
    • Osório, J.1
  • 70
    • 84982177954 scopus 로고    scopus 로고
    • Injecting engineered anti-inflammatory macrophages therapeutically induces white adipose tissue browning and improves diet-induced insulin resistance
    • P. S. Liu, Y. W. Lin, F. H. Burton, and L. N. Wei, "Injecting engineered anti-inflammatory macrophages therapeutically induces white adipose tissue browning and improves diet-induced insulin resistance, " Adipocyte, vol. 4, no. 2, pp. 123-128, 2015.
    • (2015) Adipocyte , vol.4 , Issue.2 , pp. 123-128
    • Liu, P.S.1    Lin, Y.W.2    Burton, F.H.3    Wei, L.N.4
  • 71
    • 84949255874 scopus 로고    scopus 로고
    • Eosinophils reduce chronic inflammation in adipose tissue by secreting Th2 cytokines and promoting M2 macrophages polarization
    • Y. Zhang, P. Yang, R. Cui et al., "Eosinophils reduce chronic inflammation in adipose tissue by secreting Th2 cytokines and promoting M2 macrophages polarization, " International Journal of Endocrinology, vol. 2015, Article ID 565760, 5 pages, 2015.
    • (2015) International Journal of Endocrinology , vol.2015
    • Zhang, Y.1    Yang, P.2    Cui, R.3
  • 72
    • 84937618997 scopus 로고    scopus 로고
    • Interleukin-33 and interferon-counter-regulate group 2 innate lymphoid cell activation during immune perturbation
    • A. B. Molofsky, F. Van Gool, H.-E. Liang et al., "Interleukin-33 and interferon-counter-regulate group 2 innate lymphoid cell activation during immune perturbation, " Immunity, vol. 43, no. 1, pp. 161-174, 2015.
    • (2015) Immunity , vol.43 , Issue.1 , pp. 161-174
    • Molofsky, A.B.1    Van Gool, F.2    Liang, H.-E.3
  • 73
    • 84925873107 scopus 로고    scopus 로고
    • Immune regulation of metabolic homeostasis in health and disease
    • J. R. Brestoff and D. Artis, "Immune regulation of metabolic homeostasis in health and disease, " Cell, vol. 161, no. 1, pp. 146-160, 2015.
    • (2015) Cell , vol.161 , Issue.1 , pp. 146-160
    • Brestoff, J.R.1    Artis, D.2
  • 74
    • 84880812042 scopus 로고    scopus 로고
    • MiR-133a regulates adipocyte browning in vivo
    • W. Liu, P. Bi, T. Shan et al., "miR-133a regulates adipocyte browning in vivo, " PLoS Genetics, vol. 9, no. 7, Article ID e1003626, 2013.
    • (2013) PLoS Genetics , vol.9 , Issue.7
    • Liu, W.1    Bi, P.2    Shan, T.3
  • 75
    • 79960984113 scopus 로고    scopus 로고
    • Mir193b-365 is essential for brown fat differentiation
    • L. Sun, H. Xie, M. A. Mori et al., "Mir193b-365 is essential for brown fat differentiation, " Nature Cell Biology, vol. 13, no. 8, pp. 958-965, 2011.
    • (2011) Nature Cell Biology , vol.13 , Issue.8 , pp. 958-965
    • Sun, L.1    Xie, H.2    Mori, M.A.3
  • 76
    • 84870595878 scopus 로고    scopus 로고
    • MyomiR-133 regulates brown fat differentiation through Prdm16
    • M. Trajkovski, K. Ahmed, C. C. Esau, andM. Stoffel, "MyomiR-133 regulates brown fat differentiation through Prdm16, " Nature Cell Biology, vol. 14, no. 12, pp. 1330-1335, 2012.
    • (2012) Nature Cell Biology , vol.14 , Issue.12 , pp. 1330-1335
    • Trajkovski, M.1    Ahmed, K.2    Esau, C.C.3    Stoffel, M.4
  • 77
    • 84941180494 scopus 로고    scopus 로고
    • MiR-93 controls adiposity via inhibition of Sirt7 and Tbx3
    • M. Cioffi, M. Vallespinos-Serrano, S. M. Trabulo et al., "MiR-93 controls adiposity via inhibition of Sirt7 and Tbx3, " Cell Reports, vol. 12, no. 10, pp. 1594-1605, 2015.
    • (2015) Cell Reports , vol.12 , Issue.10 , pp. 1594-1605
    • Cioffi, M.1    Vallespinos-Serrano, M.2    Trabulo, S.M.3
  • 78
    • 84860009214 scopus 로고    scopus 로고
    • Essential role for miR-196a in brown adipogenesis of white fat progenitor cells
    • M. Mori, H. Nakagami, G. Rodriguez-Araujo, K. Nimura, and Y. Kaneda, "Essential role for miR-196a in brown adipogenesis of white fat progenitor cells, " PLoS Biology, vol. 10, no. 4, Article ID e1001314, 2012.
    • (2012) PLoS Biology , vol.10 , Issue.4
    • Mori, M.1    Nakagami, H.2    Rodriguez-Araujo, G.3    Nimura, K.4    Kaneda, Y.5
  • 79
    • 84907377132 scopus 로고    scopus 로고
    • MicroRNA-378 controls classical brown fat expansion to counteract obesity
    • D. Pan, C. Mao, B. Quattrochi et al., "MicroRNA-378 controls classical brown fat expansion to counteract obesity, " Nature Communications, vol. 5, article 4725, 2014.
    • (2014) Nature Communications , vol.5
    • Pan, D.1    Mao, C.2    Quattrochi, B.3
  • 80
    • 84981516812 scopus 로고    scopus 로고
    • MiR-30 Promotes Thermogenesis and the Development of Beige Fat by Targeting RIP140
    • F. Hu, M. Wang, T. Xiao et al., "miR-30 Promotes Thermogenesis and the Development of Beige Fat by Targeting RIP140, " Diabetes, vol. 64, no. 6, pp. 2056-2068, 2015.
    • (2015) Diabetes , vol.64 , Issue.6 , pp. 2056-2068
    • Hu, F.1    Wang, M.2    Xiao, T.3
  • 81
    • 84908868680 scopus 로고    scopus 로고
    • MicroRNA 34a inhibits beige and brown fat formation in obesity in part by suppressing adipocyte fibroblast growth factor 21 signaling and SIRT1 function
    • T. Fu, S. Seok, S. Choi et al., "MicroRNA 34a inhibits beige and brown fat formation in obesity in part by suppressing adipocyte fibroblast growth factor 21 signaling and SIRT1 function, " Molecular and Cellular Biology, vol. 34, no. 22, pp. 4130-4142, 2014.
    • (2014) Molecular and Cellular Biology , vol.34 , Issue.22 , pp. 4130-4142
    • Fu, T.1    Seok, S.2    Choi, S.3
  • 82
    • 84901423103 scopus 로고    scopus 로고
    • MicroRNA-26 family is required for human adipogenesis and drives characteristics of brown adipocytes
    • M. Karbiener, D. F. Pisani, A. Frontini et al., "MicroRNA-26 family is required for human adipogenesis and drives characteristics of brown adipocytes, " STEM CELLS, vol. 32, no. 6, pp. 1578-1590, 2014.
    • (2014) STEM CELLS , vol.32 , Issue.6 , pp. 1578-1590
    • Karbiener, M.1    Pisani, D.F.2    Frontini, A.3
  • 83
    • 84928192649 scopus 로고    scopus 로고
    • De novo reconstruction of adipose tissue transcriptomes reveals long noncoding RNA regulators of brown adipocyte development
    • J. R. Alvarez-Dominguez, Z. Bai, D. Xu et al., "De novo reconstruction of adipose tissue transcriptomes reveals long noncoding RNA regulators of brown adipocyte development, " Cell Metabolism, vol. 21, no. 5, pp. 764-776, 2015.
    • (2015) Cell Metabolism , vol.21 , Issue.5 , pp. 764-776
    • Alvarez-Dominguez, J.R.1    Bai, Z.2    Xu, D.3
  • 85
    • 50049127055 scopus 로고    scopus 로고
    • New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure
    • Y.-H. Tseng, E. Kokkotou, T. J. Schulz et al., "New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure, " Nature, vol. 454, no. 7207, pp. 1000-1004, 2008.
    • (2008) Nature , vol.454 , Issue.7207 , pp. 1000-1004
    • Tseng, Y.-H.1    Kokkotou, E.2    Schulz, T.J.3
  • 86
    • 84860850964 scopus 로고    scopus 로고
    • BMP8B increases brown adipose tissue thermogenesis through both central and peripheral actions
    • A. J. Whittle, S. Carobbio, L. Martins et al., "BMP8B increases brown adipose tissue thermogenesis through both central and peripheral actions, " Cell, vol. 149, no. 4, pp. 871-885, 2012.
    • (2012) Cell , vol.149 , Issue.4 , pp. 871-885
    • Whittle, A.J.1    Carobbio, S.2    Martins, L.3
  • 87
    • 84863012022 scopus 로고    scopus 로고
    • FGF21 regulates PGC-1 and browning of white adipose tissues in adaptive thermogenesis
    • F. M. Fisher, S. Kleiner, N. Douris et al., "FGF21 regulates PGC-1 and browning of white adipose tissues in adaptive thermogenesis, " Genes & Development, vol. 26, no. 3, pp. 271-281, 2012.
    • (2012) Genes & Development , vol.26 , Issue.3 , pp. 271-281
    • Fisher, F.M.1    Kleiner, S.2    Douris, N.3
  • 88
    • 84893849860 scopus 로고    scopus 로고
    • Interplay between FGF21 and insulin action in the liver regulates metabolism
    • B. Emanuelli, S. G. Vienberg, G. Smyth et al., "Interplay between FGF21 and insulin action in the liver regulates metabolism, " The Journal of Clinical Investigation, vol. 124, no. 2, pp. 515-527, 2014.
    • (2014) The Journal of Clinical Investigation , vol.124 , Issue.2 , pp. 515-527
    • Emanuelli, B.1    Vienberg, S.G.2    Smyth, G.3
  • 89
    • 77952970098 scopus 로고    scopus 로고
    • Cyclooxygenase-2 controls energy homeostasis in mice by de novo recruitment of brown adipocytes
    • A. Vegiopoulos, K. Müller-Decker, D. Strzoda et al., "Cyclooxygenase-2 controls energy homeostasis in mice by de novo recruitment of brown adipocytes, " Science, vol. 328, no. 5982, pp. 1158-1161, 2010.
    • (2010) Science , vol.328 , Issue.5982 , pp. 1158-1161
    • Vegiopoulos, A.1    Müller-Decker, K.2    Strzoda, D.3
  • 90
    • 84956709773 scopus 로고    scopus 로고
    • Transcriptional pathways in cPGI2-induced adipocyte progenitor activation for browning
    • I. Bayindir, R. Babaeikelishomi, S. Kocanova et al., "Transcriptional pathways in cPGI2-induced adipocyte progenitor activation for browning, " Frontiers in Endocrinology, vol. 6, article 129, 2015.
    • (2015) Frontiers in Endocrinology , vol.6
    • Bayindir, I.1    Babaeikelishomi, R.2    Kocanova, S.3
  • 91
    • 84863229962 scopus 로고    scopus 로고
    • Cardiac natriuretic peptides act via p38MAPKto induce the brownfat thermogenic program in mouse and human adipocytes
    • M. Bordicchia, D. Liu, E.-Z. Amri et al., "Cardiac natriuretic peptides act via p38MAPKto induce the brownfat thermogenic program in mouse and human adipocytes, " The Journal of Clinical Investigation, vol. 122, no. 3, pp. 1022-1036, 2012.
    • (2012) The Journal of Clinical Investigation , vol.122 , Issue.3 , pp. 1022-1036
    • Bordicchia, M.1    Liu, D.2    Amri, E.-Z.3
  • 92
    • 84884761856 scopus 로고    scopus 로고
    • Coordinate functional regulation between microsomal prostaglandin e synthase-1 (mPGES-1) and peroxisome proliferator-activated receptor (PPAR) in the conversion of white-to-brown adipocytes
    • V. Garcá-Alonso, C. López-Vicario, E. Titos et al., "Coordinate functional regulation between microsomal prostaglandin E synthase-1 (mPGES-1) and peroxisome proliferator-activated receptor (PPAR) in the conversion of white-to-brown adipocytes, " The Journal of Biological Chemistry, vol. 288, no. 39, pp. 28230-28242, 2013.
    • (2013) The Journal of Biological Chemistry , vol.288 , Issue.39 , pp. 28230-28242
    • Garcá-Alonso, V.1    López-Vicario, C.2    Titos, E.3
  • 93
    • 53049107359 scopus 로고    scopus 로고
    • Reassessing the cardiovascular risks and benefits of thiazolidinediones
    • A. Zinn, S. Felson, E. Fisher, and A. Schwartzbard, "Reassessing the cardiovascular risks and benefits of thiazolidinediones, " Clinical Cardiology, vol. 31, no. 9, pp. 397-403, 2008.
    • (2008) Clinical Cardiology , vol.31 , Issue.9 , pp. 397-403
    • Zinn, A.1    Felson, S.2    Fisher, E.3    Schwartzbard, A.4
  • 94
    • 84920403959 scopus 로고    scopus 로고
    • Browning of human adipocytes requires KLF11 and reprogramming of PPAR superenhancers
    • A. Loft, I. Forss, M. S. Siersbæk et al., "Browning of human adipocytes requires KLF11 and reprogramming of PPAR superenhancers, " Genes & Development, vol. 29, no. 1, pp. 7-22, 2015.
    • (2015) Genes & Development , vol.29 , Issue.1 , pp. 7-22
    • Loft, A.1    Forss, I.2    Siersbæk, M.S.3
  • 95
    • 84903550477 scopus 로고    scopus 로고
    • Can a selective PPAR modulator improve glycemic control in patients with type 2 diabetes with fewer side effects compared with pioglitazone
    • A. M. DePaoli, L. S. Higgins, R. R. Henry, C. Mantzoros, and F. L. Dunn, "Can a selective PPAR modulator improve glycemic control in patients with type 2 diabetes with fewer side effects compared with pioglitazone" Diabetes Care, vol. 37, no. 7, pp. 1918-1923, 2014.
    • (2014) Diabetes Care , vol.37 , Issue.7 , pp. 1918-1923
    • DePaoli, A.M.1    Higgins, L.S.2    Henry, R.R.3    Mantzoros, C.4    Dunn, F.L.5
  • 96
    • 84861556786 scopus 로고    scopus 로고
    • Roles for peroxisome proliferator-activated receptor (PPAR) and PPAR coactivators 1 and 1 in regulating response of white and brown adipocytes to hypoxia
    • E. Pino, H. Wang, M. E. McDonald, L. Qiang, and S. R. Farmer, "Roles for peroxisome proliferator-activated receptor (PPAR) and PPAR coactivators 1 and 1 in regulating response of white and brown adipocytes to hypoxia, " The Journal of Biological Chemistry, vol. 287, no. 22, pp. 18351-18358, 2012.
    • (2012) The Journal of Biological Chemistry , vol.287 , Issue.22 , pp. 18351-18358
    • Pino, E.1    Wang, H.2    McDonald, M.E.3    Qiang, L.4    Farmer, S.R.5
  • 97
    • 84856552055 scopus 로고    scopus 로고
    • Xanthigen suppresses preadipocyte differentiation and adipogenesis through down-regulation of PPAR and C/EBPs andmodulation of SIRT-1, AMPK, and FoxO pathways
    • C.-S. Lai, M.-L. Tsai, V. Badmaev, M. Jimenez, C.-T. Ho, andM.-H. Pan, "Xanthigen suppresses preadipocyte differentiation and adipogenesis through down-regulation of PPAR and C/EBPs andmodulation of SIRT-1, AMPK, and FoxO pathways, " Journal of Agricultural and Food Chemistry, vol. 60, no. 4, pp. 1094-1101, 2012.
    • (2012) Journal of Agricultural and Food Chemistry , vol.60 , Issue.4 , pp. 1094-1101
    • Lai, C.-S.1    Tsai, M.-L.2    Badmaev, V.3    Jimenez, M.4    Ho, C.-T.5    Pan, M.-H.6
  • 98
    • 84858039282 scopus 로고    scopus 로고
    • PPAR agonists induce a white-to-brown fat conversion through stabilization of PRDM16 protein
    • H. Ohno, K. Shinoda, B. M. Spiegelman, and S. Kajimura, "PPAR agonists induce a white-to-brown fat conversion through stabilization of PRDM16 protein, " CellMetabolism, vol. 15, no. 3, pp. 395-404, 2012.
    • (2012) CellMetabolism , vol.15 , Issue.3 , pp. 395-404
    • Ohno, H.1    Shinoda, K.2    Spiegelman, B.M.3    Kajimura, S.4
  • 99
    • 84911933989 scopus 로고    scopus 로고
    • Adipose tissues and thyroid hormones
    • M.-J. Obregon, "Adipose tissues and thyroid hormones, " Frontiers in Physiology, vol. 5, article 479, 2014.
    • (2014) Frontiers in Physiology , vol.5
    • Obregon, M.-J.1
  • 100
    • 84897876705 scopus 로고    scopus 로고
    • Estrogen deficiency and the origin of obesity during menopause
    • F. Lizcano and G. Guzmán, "Estrogen deficiency and the origin of obesity during menopause, " BioMed Research International, vol. 2014, Article ID757461, 11 pages, 2014.
    • (2014) BioMed Research International , vol.2014
    • Lizcano, F.1    Guzmán, G.2
  • 101
    • 84904040735 scopus 로고    scopus 로고
    • GPS2/KDM4A pioneering activity regulates promoter-specific recruitment of PPAR
    • M. D. Cardamone, B. Tanasa, M. Chan et al., "GPS2/KDM4A pioneering activity regulates promoter-specific recruitment of PPAR, " Cell Reports, vol. 8, no. 1, pp. 163-176, 2014.
    • (2014) Cell Reports , vol.8 , Issue.1 , pp. 163-176
    • Cardamone, M.D.1    Tanasa, B.2    Chan, M.3
  • 102
    • 79851490315 scopus 로고    scopus 로고
    • Regulation of adipogenesis by nuclear receptor PPAR is modulated by the histone demethylase JMJD2C
    • F. Lizcano, C. Romero, and D. Vargas, "Regulation of adipogenesis by nuclear receptor PPAR is modulated by the histone demethylase JMJD2C, " Genetics and Molecular Biology, vol. 34, no. 1, pp. 19-24, 2011.
    • (2011) Genetics and Molecular Biology , vol.34 , Issue.1 , pp. 19-24
    • Lizcano, F.1    Romero, C.2    Vargas, D.3
  • 103
    • 84929207487 scopus 로고    scopus 로고
    • JMJD1A is a signalsensing scaffold that regulates acute chromatin dynamics via SWI/SNF association for thermogenesis
    • Y. Abe, R. Rozqie, Y. Matsumura et al., "JMJD1A is a signalsensing scaffold that regulates acute chromatin dynamics via SWI/SNF association for thermogenesis, " Nature Communications, vol. 6, article 7052, 2015.
    • (2015) Nature Communications , vol.6
    • Abe, Y.1    Rozqie, R.2    Matsumura, Y.3
  • 104
    • 68049095260 scopus 로고    scopus 로고
    • Obesity and metabolic syndrome in histone demethylase JHDM2a-deficient mice
    • T. Inagaki, M. Tachibana, K. Magoori et al., "Obesity and metabolic syndrome in histone demethylase JHDM2a-deficient mice, " Genes to Cells, vol. 14, no. 8, pp. 991-1001, 2009.
    • (2009) Genes to Cells , vol.14 , Issue.8 , pp. 991-1001
    • Inagaki, T.1    Tachibana, M.2    Magoori, K.3
  • 105
    • 64749111074 scopus 로고    scopus 로고
    • Role of Jhdm2a in regulating metabolic gene expression and obesity resistance
    • K. Tateishi, Y. Okada, E. M. Kallin, and Y. Zhang, "Role of Jhdm2a in regulating metabolic gene expression and obesity resistance, " Nature, vol. 458, no. 7239, pp. 757-761, 2009.
    • (2009) Nature , vol.458 , Issue.7239 , pp. 757-761
    • Tateishi, K.1    Okada, Y.2    Kallin, E.M.3    Zhang, Y.4
  • 106
    • 84889604511 scopus 로고    scopus 로고
    • EHMT1 controls brown adipose cell fate and thermogenesis through the PRDM16 complex
    • H. Ohno, K. Shinoda, K. Ohyama, L. Z. Sharp, and S. Kajimura, "EHMT1 controls brown adipose cell fate and thermogenesis through the PRDM16 complex, " Nature, vol. 504, no. 7478, pp. 163-167, 2013.
    • (2013) Nature , vol.504 , Issue.7478 , pp. 163-167
    • Ohno, H.1    Shinoda, K.2    Ohyama, K.3    Sharp, L.Z.4    Kajimura, S.5
  • 107
    • 0037374847 scopus 로고    scopus 로고
    • Cryptic terminal deletion of chromosome 9q34: A novel cause of syndromic obesity in childhood
    • V. Cormier-Daire, F. Molinari, M. Rio et al., "Cryptic terminal deletion of chromosome 9q34: a novel cause of syndromic obesity in childhood" Journal of Medical Genetics, vol. 40, no. 4, pp. 300-303, 2003.
    • (2003) Journal of Medical Genetics , vol.40 , Issue.4 , pp. 300-303
    • Cormier-Daire, V.1    Molinari, F.2    Rio, M.3
  • 108
    • 84926220100 scopus 로고    scopus 로고
    • Activation of classical brown adipocytes in the adult human perirenal depot is highly correlated with PRDM16-EHMT1 complex expression
    • G. Nagano, H. Ohno, K. Oki et al., "Activation of classical brown adipocytes in the adult human perirenal depot is highly correlated with PRDM16-EHMT1 complex expression, " PLoS ONE, vol. 10, no. 3, Article IDe0122584, 2015.
    • (2015) PLoS ONE , vol.10 , Issue.3
    • Nagano, G.1    Ohno, H.2    Oki, K.3
  • 109
    • 84964668099 scopus 로고    scopus 로고
    • Histone deacetylase 1 (HDAC1) negatively regulates thermogenic programin brown adipocytes via coordinated regulation of histone H3 Lysine 27 (H3K27) deacetylation and methylation
    • F. Li, R. Wu, X. Cui et al., "Histone deacetylase 1 (HDAC1) negatively regulates thermogenic programin brown adipocytes via coordinated regulation of histone H3 Lysine 27 (H3K27) deacetylation and methylation, "The Journal of Biological Chemistry, vol. 291, no. 9, pp. 4523-4536, 2016.
    • (2016) The Journal of Biological Chemistry , vol.291 , Issue.9 , pp. 4523-4536
    • Li, F.1    Wu, R.2    Cui, X.3
  • 110
    • 84943778234 scopus 로고    scopus 로고
    • The histone demethylase UTX promotes brown adipocyte thermogenic program via coordinated regulation of H3K27 demethylation and acetylation
    • L. Zha, F. Li, R. Wu et al., "The histone demethylase UTX promotes brown adipocyte thermogenic program via coordinated regulation of H3K27 demethylation and acetylation, " The Journal of Biological Chemistry, vol. 290, no. 41, pp. 25151-25163, 2015.
    • (2015) The Journal of Biological Chemistry , vol.290 , Issue.41 , pp. 25151-25163
    • Zha, L.1    Li, F.2    Wu, R.3
  • 111
    • 84942924082 scopus 로고    scopus 로고
    • Transcriptomic profiling and H3K27me3 distribution reveal both demethylasedependent and independent regulation of developmental gene transcription in cell differentiation
    • S. C. Kang, S. K. Kim, J. C. Chai et al., "Transcriptomic profiling and H3K27me3 distribution reveal both demethylasedependent and independent regulation of developmental gene transcription in cell differentiation, " PLoS ONE, vol. 10, no. 8, Article ID 0135276, 2015.
    • (2015) PLoS ONE , vol.10 , Issue.8
    • Kang, S.C.1    Kim, S.K.2    Chai, J.C.3
  • 112
    • 84875986578 scopus 로고    scopus 로고
    • Cooperative activation of tissue-specific genes by pRB and E2F1
    • S. Flowers, F. Xu, and E. Moran, "Cooperative activation of tissue-specific genes by pRB and E2F1, " Cancer Research, vol. 73, no. 7, pp. 2150-2158, 2013.
    • (2013) Cancer Research , vol.73 , Issue.7 , pp. 2150-2158
    • Flowers, S.1    Xu, F.2    Moran, E.3
  • 114
    • 84865781554 scopus 로고    scopus 로고
    • Beige differentiation of adipose depots in mice lacking prolactin receptor protects against high-fat-diet-induced obesity
    • J. Auffret, S. Viengchareun, N. Carré et al., "Beige differentiation of adipose depots in mice lacking prolactin receptor protects against high-fat-diet-induced obesity, " The FASEB Journal, vol. 26, no. 9, pp. 3728-3737, 2012.
    • (2012) The FASEB Journal , vol.26 , Issue.9 , pp. 3728-3737
    • Auffret, J.1    Viengchareun, S.2    Carré, N.3
  • 115
    • 84899030336 scopus 로고    scopus 로고
    • P107 is a crucial regulator for determining the adipocyte lineage fate choices of stem cells
    • M. De Sousa, D. P. Porras, C. G. R. Perry, P. Seale, and A. Scimè, "P107 is a crucial regulator for determining the adipocyte lineage fate choices of stem cells, " STEM CELLS, vol. 32, no. 5, pp. 1323-1336, 2014.
    • (2014) STEM CELLS , vol.32 , Issue.5 , pp. 1323-1336
    • De Sousa, M.1    Porras, D.P.2    Perry, C.G.R.3    Seale, P.4    Scimè, A.5
  • 117
    • 44849132591 scopus 로고    scopus 로고
    • Dynamics of fat cell turnover in humans
    • K. L. Spalding, E. Arner, P. O. Westermark et al., "Dynamics of fat cell turnover in humans, " Nature, vol. 453, no. 7196, pp. 783-787, 2008.
    • (2008) Nature , vol.453 , Issue.7196 , pp. 783-787
    • Spalding, K.L.1    Arner, E.2    Westermark, P.O.3
  • 119
    • 9144223683 scopus 로고    scopus 로고
    • Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
    • H. Xu, G. T. Barnes, Q. Yang et al., "Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance, "The Journal of Clinical Investigation, vol. 112, no. 12, pp. 1821-1830, 2003.
    • (2003) The Journal of Clinical Investigation , vol.112 , Issue.12 , pp. 1821-1830
    • Xu, H.1    Barnes, G.T.2    Yang, Q.3
  • 120
    • 84881221754 scopus 로고    scopus 로고
    • Recruited brown adipose tissue as an antiobesity agent in humans
    • T. Yoneshiro, S. Aita, M. Matsushita et al., "Recruited brown adipose tissue as an antiobesity agent in humans, " Journal of Clinical Investigation, vol. 123, no. 8, pp. 3404-3408, 2013.
    • (2013) Journal of Clinical Investigation , vol.123 , Issue.8 , pp. 3404-3408
    • Yoneshiro, T.1    Aita, S.2    Matsushita, M.3
  • 121
    • 84911896533 scopus 로고    scopus 로고
    • Brown adipose tissue improves whole-body glucose homeostasis and insulin sensitivity in humans
    • M. Chondronikola, E. Volpi, E. Børsheimet al., "Brown adipose tissue improves whole-body glucose homeostasis and insulin sensitivity in humans, " Diabetes, vol. 63, no. 12, pp. 4089-4099, 2014.
    • (2014) Diabetes , vol.63 , Issue.12 , pp. 4089-4099
    • Chondronikola, M.1    Volpi, E.2    Børsheim, E.3
  • 122
    • 84949814146 scopus 로고    scopus 로고
    • Unlock the thermogenic potential of adipose tissue: Pharmacologicalmodulation and implications for treatment of diabetes and obesity
    • X.-R. Peng, P. Gennemark, G. O'Mahony, and S. Bartesaghi, "Unlock the thermogenic potential of adipose tissue: pharmacologicalmodulation and implications for treatment of diabetes and obesity, " Frontiers in Endocrinology, vol. 6, article 174, 2015.
    • (2015) Frontiers in Endocrinology , vol.6
    • Peng, X.-R.1    Gennemark, P.2    O'Mahony, G.3    Bartesaghi, S.4
  • 123
    • 84975757439 scopus 로고    scopus 로고
    • Acreatinedriven substrate cycle enhances energy expenditure and thermogenesis in beige fat
    • L. Kazak, E. T. Chouchani, M. P. Jedrychowski et al., "Acreatinedriven substrate cycle enhances energy expenditure and thermogenesis in beige fat, " Cell, vol. 163, no. 3, pp. 643-655, 2015.
    • (2015) Cell , vol.163 , Issue.3 , pp. 643-655
    • Kazak, L.1    Chouchani, E.T.2    Jedrychowski, M.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.