메뉴 건너뛰기




Volumn 157, Issue 3, 2016, Pages 983-996

Role of hypothalamic VGF in energy balance and metabolic adaption to environmental enrichment in mice

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CRE RECOMBINASE; LEPTIN; MELANOCORTIN; MELANOCORTIN RECEPTOR AGONIST; NERVE GROWTH FACTOR; PARVOVIRUS VECTOR; PROTEIN VGF; UNCLASSIFIED DRUG; GLUCOSE BLOOD LEVEL; MELANOCORTIN RECEPTOR; NEUROPEPTIDE; VGF PROTEIN, MOUSE;

EID: 84960538964     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2015-1627     Document Type: Article
Times cited : (26)

References (48)
  • 1
    • 4444228888 scopus 로고    scopus 로고
    • Fact Sheet No. 311. Geneva, Switzerland: World Health Organization
    • World Health Organization. Obesity and overweight. Fact Sheet No. 311. Geneva, Switzerland: World Health Organization; 2015.
    • (2015) Obesity and Overweight
    • World Health Organization1
  • 3
    • 77954275244 scopus 로고    scopus 로고
    • Environmental and genetic activation of a brain-adipocyte BDNF/leptin axis causes cancer remission and inhibition
    • Cao L, Liu X, Lin EJ, et al. Environmental and genetic activation of a brain-adipocyte BDNF/leptin axis causes cancer remission and inhibition. Cell. 2010;142:52-64.
    • (2010) Cell , vol.142 , pp. 52-64
    • Cao, L.1    Liu, X.2    Lin, E.J.3
  • 4
    • 64149127594 scopus 로고    scopus 로고
    • Molecular therapy of obesity and diabetes by a physiological autoregulatory approach
    • Cao L, Lin EJ, Cahill MC, Wang C, Liu X, During MJ. Molecular therapy of obesity and diabetes by a physiological autoregulatory approach. Nat Med. 2009;15:447-454.
    • (2009) Nat Med. , vol.15 , pp. 447-454
    • Cao, L.1    Lin, E.J.2    Cahill, M.C.3    Wang, C.4    Liu, X.5    During, M.J.6
  • 5
    • 80052739107 scopus 로고    scopus 로고
    • White to brown fat phenotypic switch induced by genetic and environmental activationof a hypothalamicadipocyte axis
    • Cao L, Choi EY, Liu X, et al. White to brown fat phenotypic switch induced by genetic and environmental activationof a hypothalamicadipocyte axis. Cell Metab. 2011;14:324-338.
    • (2011) Cell Metab. , vol.14 , pp. 324-338
    • Cao, L.1    Choi, E.Y.2    Liu, X.3
  • 6
    • 84862674310 scopus 로고    scopus 로고
    • What is the brain-cancer connection?
    • Cao L, During MJ. What is the brain-cancer connection? Annu Rev Neurosci. 2012;35:331-345.
    • (2012) Annu Rev Neurosci. , vol.35 , pp. 331-345
    • Cao, L.1    During, M.J.2
  • 7
    • 84903772529 scopus 로고    scopus 로고
    • Hypothalamic gene transfer of BDNF inhibits breast cancer progression and metastasis in middle age obese mice
    • Liu X, McMurphy T, Xiao R, Slater A, Huang W, Cao L. Hypothalamic gene transfer of BDNF inhibits breast cancer progression and metastasis in middle age obese mice. Mol Ther. 2014;22:1275-1284.
    • (2014) Mol Ther. , vol.22 , pp. 1275-1284
    • Liu, X.1    McMurphy, T.2    Xiao, R.3    Slater, A.4    Huang, W.5    Cao, L.6
  • 8
    • 84930443140 scopus 로고    scopus 로고
    • Adipose VEGF links the white-to-brown fat switch with environmental, genetic, and pharmacological stimuli in male mice
    • During MJ, Liu X, Huang W, et al. Adipose VEGF links the white-to-brown fat switch with environmental, genetic, and pharmacological stimuli in male mice. Endocrinology. 2015;156:2059-2073.
    • (2015) Endocrinology , vol.156 , pp. 2059-2073
    • During, M.J.1    Liu, X.2    Huang, W.3
  • 9
    • 0021796469 scopus 로고
    • Molecular cloning of a gene sequence regulated by nerve growth factor
    • Levi A, Eldridge JD, Paterson BM. Molecular cloning of a gene sequence regulated by nerve growth factor. Science. 1985;229:393-395.
    • (1985) Science , vol.229 , pp. 393-395
    • Levi, A.1    Eldridge, J.D.2    Paterson, B.M.3
  • 11
    • 0024851649 scopus 로고
    • Hypothalamic expression of a novel gene product, VGF: Immunocytochemical analysis
    • van den Pol AN, Decavel C, Levi A, Paterson B. Hypothalamic expression of a novel gene product, VGF: immunocytochemical analysis. J Neurosci. 1989;9:4122-4137.
    • (1989) J Neurosci. , vol.9 , pp. 4122-4137
    • Van Den Pol, A.N.1    Decavel, C.2    Levi, A.3    Paterson, B.4
  • 12
    • 0032571818 scopus 로고    scopus 로고
    • Developmental expression of VGF mRNA in the prenatal and postnatal rat
    • Snyder SE, Pintar JE, Salton SR. Developmental expression of VGF mRNA in the prenatal and postnatal rat. J Comp Neurol. 1998;394:64-90.
    • (1998) J Comp Neurol. , vol.394 , pp. 64-90
    • Snyder, S.E.1    Pintar, J.E.2    Salton, S.R.3
  • 13
    • 0032571806 scopus 로고    scopus 로고
    • Expression of VGF mRNA in the adult rat central nervous system
    • Snyder SE, Salton SR. Expression of VGF mRNA in the adult rat central nervous system. J Comp Neurol. 1998;394:91-105.
    • (1998) J Comp Neurol. , vol.394 , pp. 91-105
    • Snyder, S.E.1    Salton, S.R.2
  • 14
    • 0033931620 scopus 로고    scopus 로고
    • VGF: A novel role for this neuronal and neuroendocrine polypeptide in the regulation of energy balance
    • Salton SR, Ferri GL, Hahm S, et al. VGF: a novel role for this neuronal and neuroendocrine polypeptide in the regulation of energy balance. Front Neuroendocrinol. 2000;21:199-219.
    • (2000) Front Neuroendocrinol. , vol.21 , pp. 199-219
    • Salton, S.R.1    Ferri, G.L.2    Hahm, S.3
  • 15
    • 0344629700 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor-induced gene expression reveals novel actions of VGF in hippocampal synaptic plasticity
    • Alder J, Thakker-Varia S, Bangasser DA, et al. Brain-derived neurotrophic factor-induced gene expression reveals novel actions of VGF in hippocampal synaptic plasticity. J Neurosci. 2003;23:10800-10808.
    • (2003) J Neurosci. , vol.23 , pp. 10800-10808
    • Alder, J.1    Thakker-Varia, S.2    Bangasser, D.A.3
  • 17
    • 17844401704 scopus 로고    scopus 로고
    • Anatomy and regulation of the central melanocortin system
    • Cone RD. Anatomy and regulation of the central melanocortin system. Nat Neurosci. 2005;8:571-578.
    • (2005) Nat Neurosci. , vol.8 , pp. 571-578
    • Cone, R.D.1
  • 18
    • 19444367043 scopus 로고    scopus 로고
    • Regional-dependent increase of sympathetic innervation in rat white adipose tissue during prolonged fasting
    • Giordano A, Frontini A, Murano I, et al. Regional-dependent increase of sympathetic innervation in rat white adipose tissue during prolonged fasting. J Histochem Cytochem. 2005;53:679-687.
    • (2005) J Histochem Cytochem. , vol.53 , pp. 679-687
    • Giordano, A.1    Frontini, A.2    Murano, I.3
  • 20
  • 21
    • 33947387967 scopus 로고    scopus 로고
    • Role of the central melanocortin circuitry in adaptive thermogenesis of brown adipose tissue
    • Voss-Andreae A, Murphy JG, Ellacott KL, et al. Role of the central melanocortin circuitry in adaptive thermogenesis of brown adipose tissue. Endocrinology. 2007;148:1550-1560.
    • (2007) Endocrinology , vol.148 , pp. 1550-1560
    • Voss-Andreae, A.1    Murphy, J.G.2    Ellacott, K.L.3
  • 22
    • 0001398513 scopus 로고    scopus 로고
    • Targeted deletion of the Vgf gene indicates that the encoded secretory peptide precursor plays a novel role in the regulation of energy balance
    • Hahm S, Mizuno TM, Wu TJ, et al. Targeted deletion of the Vgf gene indicates that the encoded secretory peptide precursor plays a novel role in the regulation of energy balance. Neuron. 1999;23:537-548.
    • (1999) Neuron , vol.23 , pp. 537-548
    • Hahm, S.1    Mizuno, T.M.2    Wu, T.J.3
  • 23
    • 73349122261 scopus 로고    scopus 로고
    • Analysis of knockout mice suggests a role for VGF in the control of fat storage and energy expenditure
    • Watson E, Fargali S, Okamoto H, et al. Analysis of knockout mice suggests a role for VGF in the control of fat storage and energy expenditure. BMC Physiol. 2009;9:19.
    • (2009) BMC Physiol. , vol.9 , pp. 19
    • Watson, E.1    Fargali, S.2    Okamoto, H.3
  • 25
    • 0037104786 scopus 로고    scopus 로고
    • VGF is required for obesity induced by diet, gold thioglucose treatment, and agouti and is differentially regulated in pro-opiomelanocortin- and neuropeptide Y-containing arcuate neurons in response to fasting
    • Hahm S, Fekete C, Mizuno TM, et al. VGF is required for obesity induced by diet, gold thioglucose treatment, and agouti and is differentially regulated in pro-opiomelanocortin- and neuropeptide Y-containing arcuate neurons in response to fasting. J Neurosci. 2002;22:6929-6938.
    • (2002) J Neurosci. , vol.22 , pp. 6929-6938
    • Hahm, S.1    Fekete, C.2    Mizuno, T.M.3
  • 26
    • 27844524935 scopus 로고    scopus 로고
    • VGF ablation blocks the development of hyperinsulinemia and hyperglycemia in several mouse models of obesity
    • Watson E, Hahm S, Mizuno TM, et al. VGF ablation blocks the development of hyperinsulinemia and hyperglycemia in several mouse models of obesity. Endocrinology. 2005;146:5151-5163.
    • (2005) Endocrinology , vol.146 , pp. 5151-5163
    • Watson, E.1    Hahm, S.2    Mizuno, T.M.3
  • 27
    • 84929001025 scopus 로고    scopus 로고
    • Role of VGF-derived carboxy-terminal peptides in energy balance and reproduction: Analysis of "humanized" knockin mice expressing full-length or truncated VGF
    • Sadahiro M, Erickson C, Lin WJ, et al. Role of VGF-derived carboxy-terminal peptides in energy balance and reproduction: analysis of "humanized" knockin mice expressing full-length or truncated VGF. Endocrinology. 2015;156:1724-1738.
    • (2015) Endocrinology , vol.156 , pp. 1724-1738
    • Sadahiro, M.1    Erickson, C.2    Lin, W.J.3
  • 28
    • 33749266191 scopus 로고    scopus 로고
    • TLQP-21, a VGF-derived peptide, increases energy expenditure and prevents the early phase of diet-induced obesity
    • Bartolomucci A, La Corte G, Possenti R, et al. TLQP-21, a VGF-derived peptide, increases energy expenditure and prevents the early phase of diet-induced obesity. Proc Natl Acad Sci USA. 2006;103:14584-14589.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 14584-14589
    • Bartolomucci, A.1    La Corte, G.2    Possenti, R.3
  • 29
    • 84055219354 scopus 로고    scopus 로고
    • Characterization of a novel peripheral pro-lipolytic mechanism in mice: Role of VGF-derived peptide TLQP-21
    • Possenti R, Muccioli G, Petrocchi P, et al. Characterization of a novel peripheral pro-lipolytic mechanism in mice: role of VGF-derived peptide TLQP-21. Biochem J. 2012;441:511-522.
    • (2012) Biochem J. , vol.441 , pp. 511-522
    • Possenti, R.1    Muccioli, G.2    Petrocchi, P.3
  • 30
    • 84863515698 scopus 로고    scopus 로고
    • A VGF-derived peptide attenuates development of type 2 diabetes via enhancement of islet β-cell survival and function
    • Stephens SB, Schisler JC, Hohmeier HE, et al. A VGF-derived peptide attenuates development of type 2 diabetes via enhancement of islet β-cell survival and function. CellMetab. 2012;16:33-43.
    • (2012) CellMetab. , vol.16 , pp. 33-43
    • Stephens, S.B.1    Schisler, J.C.2    Hohmeier, H.E.3
  • 31
    • 38149097874 scopus 로고    scopus 로고
    • The role of the vgf gene and VGF-derived peptides in nutrition and metabolism
    • Bartolomucci A, Possenti R, Levi A, Pavone F, Moles A. The role of the vgf gene and VGF-derived peptides in nutrition and metabolism. Genes Nutr. 2007;2:169-180.
    • (2007) Genes Nutr. , vol.2 , pp. 169-180
    • Bartolomucci, A.1    Possenti, R.2    Levi, A.3    Pavone, F.4    Moles, A.5
  • 32
    • 77955920113 scopus 로고    scopus 로고
    • Neuroendocrine regulatory peptide-2 regulates feeding behavior via the orexin system in the hypothalamus
    • Toshinai K, Yamaguchi H, Kageyama H, et al. Neuroendocrine regulatory peptide-2 regulates feeding behavior via the orexin system in the hypothalamus. Am J Physiol Endocrinol Metab. 2010;299:E394-E401.
    • (2010) Am J Physiol Endocrinol Metab. , vol.299 , pp. E394-E401
    • Toshinai, K.1    Yamaguchi, H.2    Kageyama, H.3
  • 33
    • 78650061744 scopus 로고    scopus 로고
    • Selective expression of TLQP-21 and other VGF peptides in gastric neuroendocrine cells and modulation by feeding
    • Brancia C, Cocco C, D'Amato F, et al. Selective expression of TLQP-21 and other VGF peptides in gastric neuroendocrine cells and modulation by feeding. J Endocrinol. 2010;207:329-341.
    • (2010) J Endocrinol. , vol.207 , pp. 329-341
    • Brancia, C.1    Cocco, C.2    D'Amato, F.3
  • 34
    • 84937597506 scopus 로고    scopus 로고
    • VGF and its C-terminal peptide TLQP-62 regulate memory formation in hippocampus via a BDNF-TrkB-dependent mechanism
    • Lin WJ, Jiang C, Sadahiro M, et al. VGF and its C-terminal peptide TLQP-62 regulate memory formation in hippocampus via a BDNF-TrkB-dependent mechanism. J Neurosci. 2015;35:10343-10356.
    • (2015) J Neurosci. , vol.35 , pp. 10343-10356
    • Lin, W.J.1    Jiang, C.2    Sadahiro, M.3
  • 35
    • 3542999278 scopus 로고    scopus 로고
    • VEGF links hippocampal activity with neurogenesis, learning and memory
    • Cao L, Jiao X, Zuzga DS, et al. VEGF links hippocampal activity with neurogenesis, learning and memory. Nat Genet. 2004;36:827-835.
    • (2004) Nat Genet , vol.36 , pp. 827-835
    • Cao, L.1    Jiao, X.2    Zuzga, D.S.3
  • 36
    • 84930154280 scopus 로고    scopus 로고
    • Adipose tissue insulin receptor knockdown via a new primate-derived hybrid recombinant AAV serotype
    • Liu X, Magee D, Wang C, et al. Adipose tissue insulin receptor knockdown via a new primate-derived hybrid recombinant AAV serotype. Mol Ther Methods Clin Dev. 2014;1:8.
    • (2014) Mol Ther Methods Clin Dev. , vol.1 , pp. 8
    • Liu, X.1    Magee, D.2    Wang, C.3
  • 37
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2 (-ΔΔC (T)) method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2 (-ΔΔC (T)) method. Methods. 2001;25:402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 38
    • 0038392755 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor
    • Xu B, Goulding EH, Zang K, et al. Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor. Nat Neurosci. 2003;6:736-742.
    • (2003) Nat Neurosci. , vol.6 , pp. 736-742
    • Xu, B.1    Goulding, E.H.2    Zang, K.3
  • 39
    • 0033592920 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities
    • Lyons WE, Mamounas LA, Ricaurte GA, et al. Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities. Proc Natl Acad Sci USA. 1999;96:15239-15244.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 15239-15244
    • Lyons, W.E.1    Mamounas, L.A.2    Ricaurte, G.A.3
  • 40
    • 0034192443 scopus 로고    scopus 로고
    • A novel selective melanocortin-4 receptor agonist reduces food intake in rats and mice without producing aversive consequences
    • Benoit SC, Schwartz MW, Lachey JL, et al. A novel selective melanocortin-4 receptor agonist reduces food intake in rats and mice without producing aversive consequences. J Neurosci. 2000;20:3442-3448.
    • (2000) J Neurosci. , vol.20 , pp. 3442-3448
    • Benoit, S.C.1    Schwartz, M.W.2    Lachey, J.L.3
  • 41
    • 33847319765 scopus 로고    scopus 로고
    • Diet-induced obesity causes severe but reversible leptin resistance in arcuate melanocortin neurons
    • Enriori PJ, Evans AE, Sinnayah P, et al. Diet-induced obesity causes severe but reversible leptin resistance in arcuate melanocortin neurons. Cell Metab. 2007;5:181-194.
    • (2007) Cell Metab. , vol.5 , pp. 181-194
    • Enriori, P.J.1    Evans, A.E.2    Sinnayah, P.3
  • 42
    • 0021322138 scopus 로고
    • Thermogenic mechanisms in brown fat
    • Nicholls DG, Locke RM. Thermogenic mechanisms in brown fat. Physiol Rev. 1984;64:1-64.
    • (1984) Physiol Rev. , vol.64 , pp. 1-64
    • Nicholls, D.G.1    Locke, R.M.2
  • 43
    • 84898775542 scopus 로고    scopus 로고
    • Effects of energy status and diet on Bdnf expression in the ventromedial hypothalamus of male and female rats
    • Liu X, Zhu Z, Kalyani M, Janik JM, Shi H. Effects of energy status and diet on Bdnf expression in the ventromedial hypothalamus of male and female rats. Physiol Behav. 2014;130:99-107.
    • (2014) Physiol Behav. , vol.130 , pp. 99-107
    • Liu, X.1    Zhu, Z.2    Kalyani, M.3    Janik, J.M.4    Shi, H.5
  • 44
    • 84941241941 scopus 로고    scopus 로고
    • A protocol for housing mice in an enriched environment
    • Slater A, Cao L. A protocol for housing mice in an enriched environment. J Vis Exp. 2015; (100): e52874.
    • (2015) J Vis Exp. , Issue.100 , pp. e52874
    • Slater, A.1    Cao, L.2
  • 45
    • 33747613561 scopus 로고    scopus 로고
    • Enriched environments, experience-dependent plasticity and disorders of the nervous system
    • Nithianantharajah J, Hannan AJ. Enriched environments, experience-dependent plasticity and disorders of the nervous system. Nat Rev Neurosci. 2006;7:697-709.
    • (2006) Nat Rev Neurosci. , vol.7 , pp. 697-709
    • Nithianantharajah, J.1    Hannan, A.J.2
  • 46
    • 84896725880 scopus 로고    scopus 로고
    • A role for VGF in the hypothalamic arcuate and paraventricular nuclei in the control of energy homeostasis
    • Saderi N, Buijs FN, Salgado-Delgado R, et al. A role for VGF in the hypothalamic arcuate and paraventricular nuclei in the control of energy homeostasis. Neuroscience. 2014;265:184-195.
    • (2014) Neuroscience , vol.265 , pp. 184-195
    • Saderi, N.1    Buijs, F.N.2    Salgado-Delgado, R.3
  • 47
    • 84884560444 scopus 로고    scopus 로고
    • Identification of the C3a receptor (C3AR1) as the target of the VGF-derived peptide TLQP-21 in rodent cells
    • Hannedouche S, Beck V, Leighton-Davies J, et al. Identification of the C3a receptor (C3AR1) as the target of the VGF-derived peptide TLQP-21 in rodent cells. J Biol Chem. 2013;288:27434-27443.
    • (2013) J Biol Chem. , vol.288 , pp. 27434-27443
    • Hannedouche, S.1    Beck, V.2    Leighton-Davies, J.3
  • 48
    • 84889031700 scopus 로고    scopus 로고
    • Identification of a receptor for neuropeptide VGF and its role in neuropathic pain
    • Chen YC, Pristerá A, Ayub M, et al. Identification of a receptor for neuropeptide VGF and its role in neuropathic pain. J Biol Chem. 2013;288:34638-34646.
    • (2013) J Biol Chem. , vol.288 , pp. 34638-34646
    • Chen, Y.C.1    Pristerá, A.2    Ayub, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.