Xanthigen suppresses preadipocyte differentiation and adipogenesis through down-regulation of PPARγ and C/EBPs and modulation of SIRT-1, AMPK, and FoxO pathways

Journal of Agricultural and Food Chemistry

Volumn 60, Issue 4, 2012, Pages 1094-1101

  Lai, Ching Shu ^a   Tsai, Mei Ling ^a   Badmaev, Vladimir ^b,c   Jimenez, Miguel ^c   Ho, Chi Tang ^d   Pan, Min Hsiung ^a  

^a NATIONAL KAOHSIUNG UNIVERSITY OF APPLIED SCIENCES   (Taiwan)

^b PL Thomas Corporation   (United States)

^c PoliNat Inc   (Spain)

^d RUTGERS UNIVERSITY   (United States)

Author keywords

3T3 L1 adipocyte; AMPK; C EBPs; differentiation; FoxO; PPAR ; SIRT1; Xanthigen

Indexed keywords

ADIPOCYTES; AMPK; C/EBPS; FOXO; SIRT1; XANTHIGEN;

CYTOLOGY; DIFFERENTIATION (CALCULUS); ENZYME ACTIVITY; GLYCEROL; MOLECULAR WEIGHT; OILS AND FATS; PHOSPHORYLATION; SEED; TRANSCRIPTION FACTORS;

FATTY ACIDS;

CCAAT ENHANCER BINDING PROTEIN; FORKHEAD TRANSCRIPTION FACTOR; FUCOXANTHIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LINOLENIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PLANT EXTRACT; PUNICIC ACID; SIRT1 PROTEIN, MOUSE; SIRTUIN 1; XANTHIGEN; XANTHOPHYLL;

ADIPOCYTE; ADIPOGENESIS; ANIMAL; ARTICLE; CELL DIFFERENTIATION; CELL STRAIN 3T3; CYTOLOGY; DOWN REGULATION; DRUG EFFECT; HUMAN; INFANT; METABOLISM; MOUSE; SIGNAL TRANSDUCTION;

3T3-L1 CELLS; ADIPOCYTES; ADIPOGENESIS; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CCAAT-ENHANCER-BINDING PROTEINS; CELL DIFFERENTIATION; DOWN-REGULATION; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; INFANT; LINOLENIC ACIDS; MICE; PLANT EXTRACTS; PPAR GAMMA; SIGNAL TRANSDUCTION; SIRTUIN 1; XANTHOPHYLLS;

LYTHRACEAE;

EID: 84856552055     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf204862d     Document Type: Article

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