Lowering of amyloid beta peptide production with a small molecule inhibitor of amyloid-β precursor protein dimerization

American Journal of Neurodegenerative Diseases

Volumn 1, Issue 1, 2012, Pages 75-87

  So, Pauline P L ^a   Zeldich, Ella ^a   Seyb, Kathleen I ^b   Huang, Mickey M ^b   Concannon, John B ^b   King, Gwendalyn D ^a   Chen, Ci Di ^a   Cuny, Gregory D ^b   Glicksman, Marcie A ^b   Abraham, Carmela R ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b The Harvard Center for Neurodegeneration & Repair   (United States)

Author keywords

Alzheimer disease; Amyloid beta peptides; Amyloid precursor protein; Firefly luciferase complementation; Highthroughput screening; Protein dimerization

Indexed keywords

AMYLOID BETA PROTEIN; ANTIBODY; BETA SECRETASE; LUCIFERASE; SECRETASE;

ALZHEIMER DISEASE; ARTICLE; CELL PROLIFERATION; CYTOTOXICITY; DIMERIZATION; DOSE RESPONSE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC TRANSFECTION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; MODULATION; NERVE CELL; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN EXPRESSION; WESTERN BLOTTING;

EID: 84980053106     PISSN: None     EISSN: 2165591X     Source Type: Journal    
DOI: None     Document Type: Article

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