Luciferase fragment complementation imaging of conformational changes in the epidermal growth factor receptor

Journal of Biological Chemistry

Volumn 284, Issue 12, 2009, Pages 7474-7482

  Yang, Katherine S ^a   Ilagan, Ma Xenia G ^a   Piwnica Worms, David ^a,b   Pike, Linda J ^a,c  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

C TERMINUS; COMPLEMENTATION; CONFORMATIONAL CHANGE; CYTOPLASMIC DOMAINS; EPIDERMAL GROWTH FACTOR RECEPTORS; EPIDERMAL GROWTH FACTORS; EXTRACELLULAR; FRAGMENT COMPLEMENTATION; IN-VIVO IMAGING; INTACT CELLS; INTRACELLULAR DOMAIN; LIVE CELL; LUCIFERASE ACTIVITIES; MAP KINASE; REAL TIME; TYROSINE KINASE;

AMINO ACIDS; BIOACTIVITY; DIMERIZATION; LIGANDS; PEPTIDES; STRUCTURAL DYNAMICS;

ENZYME ACTIVITY;

EPIDERMAL GROWTH FACTOR RECEPTOR; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN TYROSINE KINASE; EPIDERMAL GROWTH FACTOR; HYBRID PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHO CELL; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIMERIZATION; ENZYME ACTIVITY; FLUORESCENCE IMAGING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FUNCTION; ANIMAL; CRICETULUS; DRUG POTENTIATION; GENETICS; HAMSTER; METABOLISM; MOUSE; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE;

ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; DIMERIZATION; EPIDERMAL GROWTH FACTOR; LUCIFERASES; MICE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECOMBINANT FUSION PROTEINS;

EID: 65549138069     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M808041200     Document Type: Article

References (41)

1. Yarden, Y., and Sliwkowski, M. X. (2001) Nat. Rev. Mol. Cell. Biol. 2, 127-137
2. Citri, A., and Yarden, Y. (2006) Nat. Rev. Mol. Cell. Biol. 7, 505-516
3. Olayioye, M. A., Neve, R. M., Lane, H. A., and Hynes, N. E. (2000) EMBO J. 19, 3159-3167
4. Jorissen, R. N., Walker, F., Pouliot, N., Garrett, T. P., Ward, C. W., and Burgess, A. W. (2003) Exp. Cell Res. 284, 31-53
5. Ullrich, A., Coussens, L., Hayflick, J. S., Dull, T. J., Gray, A., Tam, A. W., Lee, J., Yarden, Y., Libermann, T. A. Schlessinger, J., Downward, J., Mayes, E. L. V., Whittle, N., Waterfield, M. D., and Seeburg, P. H. (1984) Nature 309, 418-425
6. Yarden, Y., and Schlessinger, J. (1987) Biochemistry 26, 1443-1451
7. Sorokin, A., Lemmon, M. A., Ullrich, A., and Schlessinger, J. (1994) J. Biol. Chem. 269, 9752-9759
8. Ferguson, K. M., Berger, M. B., Mendrola, J. M., Cho, H. S., Leahy, D. J., and Lemmon, M. A. (2003) Mol. Cell 11, 507-517
9. Ogiso, H., Ishitani, R., Nureki, O., Fukai, S., Yamanaka, M., Kim, J.-H., Saito, K., Sakamoto, A., Inoue, M., Shirouzu, M., and Yokoyama, S. (2002) Cell 110, 775-787
10. Garrett, T. P., McKern, N. M., Lou, M., Elleman, T. C., Adams, T. E., Lovrecz, G. O., Zhu, H.-J., Walker, F., Frenkel, M. J., Hoyne, P. A., Jorissen, R. N., Nice, E. C., Burgess, A. W., and Ward, C. W. (2002) Cell 110, 763-773
11. Zhang, X., Gureasko, J., Shen, K., Cole, P. A., and Kuriyan, J. (2006) Cell 125, 1137-1149
12. Lee, N. Y., and Koland, J. G. (2005) Protein Sci. 14, 2793-2803
13. Cadena, D. L., Chan, C. L., and Gill, G. N. (1994) J. Biol. Chem. 269, 260-265
14. Lee, N. Y., Hazlett, T. L., and Koland, J. G. (2006) Protein Sci. 15, 1142-1152
15. Wood, E. R., Truesdale, A. T., McDonald, O. B., Yuan, D., Hassell, A., Dickerson, S. H., Ellis, B., Pennisi, C., Horne, E., Lackey, K., Alligood, K. J., Rusnak, D. W., Gilmer, T. M., and Shewchuk, L. (2004) Cancer Res. 64, 6652-6659
16. Stamos, J., Sliwkowski, M. X., and Eigenbrot, C. (2002) J. Biol. Chem. 277, 46265-46272
17. Luker, K. E., Smith, M. C., Luker, G. D., Gammon, S. T., Piwnica-Worms, H., and Piwnica-Worms, D. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 12288-12293
18. Saffarian, S., Li, Y., Elson, E. L., and Pike, L. J. (2007) Biophys. J. 93, 1021-1031
19. Macdonald, J., Li, Z., Su, W., and Pike, L. J. (2006) Biochim. Biophys. Acta 1763, 870-878
20. Macdonald, J. L., and Pike, L. J. (2008) Proc. Natl. Acad. Sci. U. S. A. 105, 112-117
21. Villalobos, V., Naik, S., and Piwnica-Worms, D. (2007) Annu. Rev. Biomed. Eng. 9, 321-349
22. Honegger, A. M., Szapary, D., Schmidt, A., Lyall, R., Van Obberghen, E., Dull, T. J., Ullrich, A., and Schlessinger, J. (1987) Mol. Cell. Biol. 7, 4568-4571
23. Takishima, K., Griswold-Prenner, I., Ingebritsen, T., and Rosner, M. R. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 2520-2524
24. Countaway, J. L., Northwood, I. C., and Davis, R. J. (1989) J. Biol. Chem. 264, 10828-10835
25. Northwood, I. C., Gonzalez, F. A., Wartmann, M., Raden, D. L., and Davis, R. J. (1991) J. Biol. Chem. 266, 15266-15276
26. Blakely, B. T., Rossi, F. M. V., Tillotson, B., Palmer, M., Estelles, A., and Blau, H. M. (2000) Nat. Biotechnol. 18, 218-222
27. Wehrman, T. S., Raab, W. J., Casipit, C. L., Doyonnas, R., Pomerantz, J. H., and Blau, H. M. (2006) Proc. Natl. Acad. Sci. U. S. A. 103, 19063-19068
28. Chantry, A. (1995) J. Biol. Chem. 270, 3068-3073
29. Yu, X., Sharma, K. D., Takahashi, T., Iwamoto, R., and Mekada, E. (2002) Mol. Biol. Cell 13, 2547-2557
30. Clayton, A. H., Walker, F., Orchard, S. G., Henderson, C., Fuchs, D., Rothacker, J., Nice, E. C., and Burgess, A. W. (2005) J. Biol. Chem. 280, 30392-30399
31. Martin-Fernandez, M., Clarke, D. T., Tobin, M. J., Jones, S. V., and Jones, G. R. (2002) Biophys. J. 82, 2415-2427
32. Arteaga, C. L., Ramsey, T. T., Shawver, L. K., and Guyer, C. A. (1997) J. Biol. Chem. 272, 23247-23254
33. Lichtner, R. B., Menrad, A., Sommer, A., Klar, U., and Schneider, M. R. (2001) Cancer Res. 61, 5790-5795
34. Gan, H. K., Walker, F., Burgess, A. W., Rigopoulos, A., Scot, A. M., and Johns, T. G. (2007) J. Biol. Chem. 282, 2840-2850
35. Liu, P., Sudhaharan, T., Koh, R. M. L., Hwang, L. C., Ahmed, S., Maruyama, I. N., and Wohland, T. (2007) Biophys. J. 93, 684-698
36. Li, X., Huang, Y., Jiang, J., and Frank, S. J. (2008) Cell Signal. 20, 2145-2155
37. Li, W., Li, F., Huang, Q., Frederick, B., Bao, S., and Li, C.-Y. (2008) Cancer Res. 68, 4990-4997
38. Margolis, B. L., Lax, I., Kris, R., Dombalagian, M., Honegger, A. M., Howk, R., Givol, D., Ullrich, A., and Schlessinger, J. (1989) J. Biol. Chem. 264, 10667-10671
39. Walton, G. M., Chen, W. S., Rosenfeld, M. G., and Gill, G. N. (1990) J. Biol. Chem. 265, 1750-1754
40. Downward, J., Parker, P., and Waterfield, M. D. (1984) Nature 311, 483-485
41. Hsuan, J. J., Totty, N., and Waterfield, M. D. (1989) Biochem. J. 262, 659-663