Copper binding to the Alzheimer's disease amyloid precursor protein

European Biophysics Journal

Volumn 37, Issue 3, 2008, Pages 269-279

  Kong, Geoffrey K W ^a,e   Miles, Luke A ^a   Crespi, Gabriela A N ^a   Morton, Craig J ^a   Ng, Hooi Ling ^a   Barnham, Kevin J ^b,c,d   McKinstry, William J ^a,f   Cappai, Roberto ^b,c,d   Parker, Michael W ^a,d  

^a ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH   (Australia)

^d UNIVERSITY OF MELBOURNE   (Australia)

^e MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^f PFIZER INC   (United States)

Author keywords

Alzheimer's disease; Amyloid precursor protein; Copper binding; Crystal structures; Receptor signalling

Indexed keywords

AMYLOID PRECURSOR PROTEIN; CARRIER PROTEIN; COPPER;

ALZHEIMER DISEASE; CONFERENCE PAPER; CONFORMATIONAL TRANSITION; COPPER BINDING; HUMAN; METAL BINDING; MODEL; PROTEIN INTERACTION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BINDING SITES; COPPER; DIMERIZATION; DOWN-REGULATION; HUMANS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; SPECTRUM ANALYSIS;

EID: 39749193587     PISSN: 01757571     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00249-007-0234-3     Document Type: Conference Paper

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