-
1
-
-
7244260258
-
T cell apoptosis and inflammatory bowel disease
-
Peppelenbosch MP & van Deventer SJ (2004) T cell apoptosis and inflammatory bowel disease. Gut 53, 1556–1558.
-
(2004)
Gut
, vol.53
, pp. 1556-1558
-
-
Peppelenbosch, M.P.1
van Deventer, S.J.2
-
2
-
-
84878768244
-
Apoptosis, necrosis and necroptosis: cell death regulation in the intestinal epithelium
-
Gunther C, Neumann H, Neurath MF & Becker C (2013) Apoptosis, necrosis and necroptosis: cell death regulation in the intestinal epithelium. Gut 62, 1062–1071.
-
(2013)
Gut
, vol.62
, pp. 1062-1071
-
-
Gunther, C.1
Neumann, H.2
Neurath, M.F.3
Becker, C.4
-
3
-
-
7244223147
-
Induction of T lymphocyte apoptosis by sulphasalazine in patients with Crohn's disease
-
Doering J, Begue B, Lentze MJ, Rieux-Laucat F, Goulet O, Schmitz J, Cerf-Bensussan N & Ruemmele FM (2004) Induction of T lymphocyte apoptosis by sulphasalazine in patients with Crohn's disease. Gut 53, 1632–1638.
-
(2004)
Gut
, vol.53
, pp. 1632-1638
-
-
Doering, J.1
Begue, B.2
Lentze, M.J.3
Rieux-Laucat, F.4
Goulet, O.5
Schmitz, J.6
Cerf-Bensussan, N.7
Ruemmele, F.M.8
-
4
-
-
73349125814
-
Significance of increased apoptosis and Bax expression in human small intestinal adenocarcinoma
-
Gao C & Wang AY (2009) Significance of increased apoptosis and Bax expression in human small intestinal adenocarcinoma. J Histochem Cytochem 57, 1139–1148.
-
(2009)
J Histochem Cytochem
, vol.57
, pp. 1139-1148
-
-
Gao, C.1
Wang, A.Y.2
-
5
-
-
7244227675
-
Apoptosis and colorectal cancer
-
Watson AJ (2004) Apoptosis and colorectal cancer. Gut 53, 1701–1709.
-
(2004)
Gut
, vol.53
, pp. 1701-1709
-
-
Watson, A.J.1
-
6
-
-
0000031083
-
Programmed cell death—II. Endocrine potentiation of the breakdown of the intersegmental muscles of silkmoths
-
Lockshin RA & Williams CM (1964) Programmed cell death—II. Endocrine potentiation of the breakdown of the intersegmental muscles of silkmoths. J Insect Physiol 10, 643–649.
-
(1964)
J Insect Physiol
, vol.10
, pp. 643-649
-
-
Lockshin, R.A.1
Williams, C.M.2
-
7
-
-
0015383455
-
Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics
-
Kerr JF, Wyllie AH & Currie AR (1972) Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26, 239–257.
-
(1972)
Br J Cancer
, vol.26
, pp. 239-257
-
-
Kerr, J.F.1
Wyllie, A.H.2
Currie, A.R.3
-
8
-
-
80053580530
-
RIPK-dependent necrosis and its regulation by caspases: a mystery in five acts
-
Green DR, Oberst A, Dillon CP, Weinlich R & Salvesen GS (2011) RIPK-dependent necrosis and its regulation by caspases: a mystery in five acts. Mol Cell 44, 9–16.
-
(2011)
Mol Cell
, vol.44
, pp. 9-16
-
-
Green, D.R.1
Oberst, A.2
Dillon, C.P.3
Weinlich, R.4
Salvesen, G.S.5
-
9
-
-
84255210700
-
Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012
-
Galluzzi L, Vitale I, Abrams JM, Alnemri ES, Baehrecke EH, Blagosklonny MV, Dawson TM, Dawson VL, El-Deiry WS, Fulda S et al. (2012) Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012. Cell Death Differ 19, 107–120.
-
(2012)
Cell Death Differ
, vol.19
, pp. 107-120
-
-
Galluzzi, L.1
Vitale, I.2
Abrams, J.M.3
Alnemri, E.S.4
Baehrecke, E.H.5
Blagosklonny, M.V.6
Dawson, T.M.7
Dawson, V.L.8
El-Deiry, W.S.9
Fulda, S.10
-
10
-
-
0036848180
-
Ex vivo whole-embryo culture of caspase-8-deficient embryos normalize their aberrant phenotypes in the developing neural tube and heart
-
Sakamaki K, Inoue T, Asano M, Sudo K, Kazama H, Sakagami J, Sakata S, Ozaki M, Nakamura S, Toyokuni S et al. (2002) Ex vivo whole-embryo culture of caspase-8-deficient embryos normalize their aberrant phenotypes in the developing neural tube and heart. Cell Death Differ 9, 1196–1206.
-
(2002)
Cell Death Differ
, vol.9
, pp. 1196-1206
-
-
Sakamaki, K.1
Inoue, T.2
Asano, M.3
Sudo, K.4
Kazama, H.5
Sakagami, J.6
Sakata, S.7
Ozaki, M.8
Nakamura, S.9
Toyokuni, S.10
-
11
-
-
0032143986
-
Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally
-
Varfolomeev EE, Schuchmann M, Luria V, Chiannilkulchai N, Beckmann JS, Mett IL, Rebrikov D, Brodianski VM, Kemper OC, Kollet O et al. (1998) Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally. Immunity 9, 267–276.
-
(1998)
Immunity
, vol.9
, pp. 267-276
-
-
Varfolomeev, E.E.1
Schuchmann, M.2
Luria, V.3
Chiannilkulchai, N.4
Beckmann, J.S.5
Mett, I.L.6
Rebrikov, D.7
Brodianski, V.M.8
Kemper, O.C.9
Kollet, O.10
-
12
-
-
80052850704
-
FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation
-
Welz PS, Wullaert A, Vlantis K, Kondylis V, Fernandez-Majada V, Ermolaeva M, Kirsch P, Sterner-Kock A, van Loo G & Pasparakis M (2011) FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation. Nature 477, 330–334.
-
(2011)
Nature
, vol.477
, pp. 330-334
-
-
Welz, P.S.1
Wullaert, A.2
Vlantis, K.3
Kondylis, V.4
Fernandez-Majada, V.5
Ermolaeva, M.6
Kirsch, P.7
Sterner-Kock, A.8
van Loo, G.9
Pasparakis, M.10
-
13
-
-
80052845560
-
Caspase-8 regulates TNF-alpha-induced epithelial necroptosis and terminal ileitis
-
Gunther C, Martini E, Wittkopf N, Amann K, Weigmann B, Neumann H, Waldner MJ, Hedrick SM, Tenzer S, Neurath MF et al. (2011) Caspase-8 regulates TNF-alpha-induced epithelial necroptosis and terminal ileitis. Nature 477, 335–339.
-
(2011)
Nature
, vol.477
, pp. 335-339
-
-
Gunther, C.1
Martini, E.2
Wittkopf, N.3
Amann, K.4
Weigmann, B.5
Neumann, H.6
Waldner, M.J.7
Hedrick, S.M.8
Tenzer, S.9
Neurath, M.F.10
-
14
-
-
84900792294
-
Die another way–non-apoptotic mechanisms of cell death
-
Tait SW, Ichim G & Green DR (2014) Die another way–non-apoptotic mechanisms of cell death. J Cell Sci 127, 2135–2144.
-
(2014)
J Cell Sci
, vol.127
, pp. 2135-2144
-
-
Tait, S.W.1
Ichim, G.2
Green, D.R.3
-
15
-
-
78649901091
-
Alternative cell death mechanisms in development and beyond
-
Yuan J & Kroemer G (2010) Alternative cell death mechanisms in development and beyond. Genes Dev 24, 2592–2602.
-
(2010)
Genes Dev
, vol.24
, pp. 2592-2602
-
-
Yuan, J.1
Kroemer, G.2
-
16
-
-
80054888589
-
It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival
-
Oberst A & Green DR (2011) It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival. Nat Rev Mol Cell Biol 12, 757–763.
-
(2011)
Nat Rev Mol Cell Biol
, vol.12
, pp. 757-763
-
-
Oberst, A.1
Green, D.R.2
-
17
-
-
0031770767
-
TNF-induced enterocyte apoptosis in mice is mediated by the TNF receptor 1 and does not require p53
-
Piguet PF, Vesin C, Guo J, Donati Y & Barazzone C (1998) TNF-induced enterocyte apoptosis in mice is mediated by the TNF receptor 1 and does not require p53. Eur J Immunol 28, 3499–3505.
-
(1998)
Eur J Immunol
, vol.28
, pp. 3499-3505
-
-
Piguet, P.F.1
Vesin, C.2
Guo, J.3
Donati, Y.4
Barazzone, C.5
-
18
-
-
84856368530
-
Enterocytes: active cells in tolerance to food and microbial antigens in the gut
-
Miron N & Cristea V (2012) Enterocytes: active cells in tolerance to food and microbial antigens in the gut. Clin Exp Immunol 167, 405–412.
-
(2012)
Clin Exp Immunol
, vol.167
, pp. 405-412
-
-
Miron, N.1
Cristea, V.2
-
19
-
-
84882809886
-
Structure and function of intestinal mucosal epithelium
-
In, 3rd Elsevier Academic Press, Burlington, MA
-
Kato T & Owen RL (2005) Structure and function of intestinal mucosal epithelium. In Mucosal Immunology, 3rd edn. pp. 131–151. Elsevier Academic Press, Burlington, MA.
-
(2005)
Mucosal Immunology
, pp. 131-151
-
-
Kato, T.1
Owen, R.L.2
-
21
-
-
0037336565
-
Signalling to and from tight junctions
-
Matter K & Balda MS (2003) Signalling to and from tight junctions. Nat Rev Mol Cell Biol 4, 225–236.
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, pp. 225-236
-
-
Matter, K.1
Balda, M.S.2
-
23
-
-
84930173219
-
Epithelial cell shedding and barrier function: a matter of life and death at the small intestinal villus tip
-
Williams JM, Duckworth CA, Burkitt MD, Watson AJ, Campbell BJ & Pritchard DM (2015) Epithelial cell shedding and barrier function: a matter of life and death at the small intestinal villus tip. Vet Pathol 52, 445–455.
-
(2015)
Vet Pathol
, vol.52
, pp. 445-455
-
-
Williams, J.M.1
Duckworth, C.A.2
Burkitt, M.D.3
Watson, A.J.4
Campbell, B.J.5
Pritchard, D.M.6
-
24
-
-
33947310779
-
Relationship between disruption of the unstirred mucus layer and intestinal restitution in loss of gut barrier function after trauma hemorrhagic shock
-
Rupani B, Caputo FJ, Watkins AC, Vega D, Magnotti LJ, Lu Q, da Xu Z & Deitch EA (2007) Relationship between disruption of the unstirred mucus layer and intestinal restitution in loss of gut barrier function after trauma hemorrhagic shock. Surgery 141, 481–489.
-
(2007)
Surgery
, vol.141
, pp. 481-489
-
-
Rupani, B.1
Caputo, F.J.2
Watkins, A.C.3
Vega, D.4
Magnotti, L.J.5
Lu, Q.6
da Xu, Z.7
Deitch, E.A.8
-
25
-
-
84884406820
-
The mucin Muc2 limits pathogen burdens and epithelial barrier dysfunction during Salmonella enterica serovar Typhimurium colitis
-
Zarepour M, Bhullar K, Montero M, Ma C, Huang T, Velcich A, Xia L & Vallance BA (2013) The mucin Muc2 limits pathogen burdens and epithelial barrier dysfunction during Salmonella enterica serovar Typhimurium colitis. Infect Immun 81, 3672–3683.
-
(2013)
Infect Immun
, vol.81
, pp. 3672-3683
-
-
Zarepour, M.1
Bhullar, K.2
Montero, M.3
Ma, C.4
Huang, T.5
Velcich, A.6
Xia, L.7
Vallance, B.A.8
-
26
-
-
0025133975
-
Tumor necrosis factor mRNA localized to Paneth cells of normal murine intestinal epithelium by in situ hybridization
-
Keshav S, Lawson L, Chung LP, Stein M, Perry VH & Gordon S (1990) Tumor necrosis factor mRNA localized to Paneth cells of normal murine intestinal epithelium by in situ hybridization. J Exp Med 171, 327–332.
-
(1990)
J Exp Med
, vol.171
, pp. 327-332
-
-
Keshav, S.1
Lawson, L.2
Chung, L.P.3
Stein, M.4
Perry, V.H.5
Gordon, S.6
-
27
-
-
84865016748
-
The intestinal epithelium tuft cells: specification and function
-
Gerbe F, Legraverend C & Jay P (2012) The intestinal epithelium tuft cells: specification and function. Cell Mol Life Sci 69, 2907–2917.
-
(2012)
Cell Mol Life Sci
, vol.69
, pp. 2907-2917
-
-
Gerbe, F.1
Legraverend, C.2
Jay, P.3
-
28
-
-
0034926810
-
Regulation of cell death and survival in intestinal intraepithelial lymphocytes
-
Brunner T, Arnold D, Wasem C, Herren S & Frutschi C (2001) Regulation of cell death and survival in intestinal intraepithelial lymphocytes. Cell Death Differ 8, 706–714.
-
(2001)
Cell Death Differ
, vol.8
, pp. 706-714
-
-
Brunner, T.1
Arnold, D.2
Wasem, C.3
Herren, S.4
Frutschi, C.5
-
29
-
-
79959664629
-
The light and dark sides of intestinal intraepithelial lymphocytes
-
Cheroutre H, Lambolez F & Mucida D (2011) The light and dark sides of intestinal intraepithelial lymphocytes. Nat Rev Immunol 11, 445–456.
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 445-456
-
-
Cheroutre, H.1
Lambolez, F.2
Mucida, D.3
-
30
-
-
62549118631
-
Wnt signaling, lgr5, and stem cells in the intestine and skin
-
Haegebarth A & Clevers H (2009) Wnt signaling, lgr5, and stem cells in the intestine and skin. Am J Pathol 174, 715–721.
-
(2009)
Am J Pathol
, vol.174
, pp. 715-721
-
-
Haegebarth, A.1
Clevers, H.2
-
31
-
-
0033043779
-
Epithelial integrity, cell death and cell loss in mammalian small intestine
-
Mayhew TM, Myklebust R, Whybrow A & Jenkins R (1999) Epithelial integrity, cell death and cell loss in mammalian small intestine. Histol Histopathol 14, 257–267.
-
(1999)
Histol Histopathol
, vol.14
, pp. 257-267
-
-
Mayhew, T.M.1
Myklebust, R.2
Whybrow, A.3
Jenkins, R.4
-
32
-
-
84929050802
-
Cell death and inflammatory bowel diseases: apoptosis, necrosis, and autophagy in the intestinal epithelium
-
Nunes T, Bernardazzi C & de Souza HS (2014) Cell death and inflammatory bowel diseases: apoptosis, necrosis, and autophagy in the intestinal epithelium. Biomed Res Int 2014, 218493.
-
(2014)
Biomed Res Int
, vol.2014
, pp. 218493
-
-
Nunes, T.1
Bernardazzi, C.2
de Souza, H.S.3
-
33
-
-
0031818266
-
New isolation technique to study apoptosis in human intestinal epithelial cells
-
Grossmann J, Maxson JM, Whitacre CM, Orosz DE, Berger NA, Fiocchi C & Levine AD (1998) New isolation technique to study apoptosis in human intestinal epithelial cells. Am J Pathol 153, 53–62.
-
(1998)
Am J Pathol
, vol.153
, pp. 53-62
-
-
Grossmann, J.1
Maxson, J.M.2
Whitacre, C.M.3
Orosz, D.E.4
Berger, N.A.5
Fiocchi, C.6
Levine, A.D.7
-
34
-
-
84862880940
-
Local barrier dysfunction identified by confocal laser endomicroscopy predicts relapse in inflammatory bowel disease
-
Kiesslich R, Duckworth CA, Moussata D, Gloeckner A, Lim LG, Goetz M, Pritchard DM, Galle PR, Neurath MF & Watson AJ (2012) Local barrier dysfunction identified by confocal laser endomicroscopy predicts relapse in inflammatory bowel disease. Gut 61, 1146–1153.
-
(2012)
Gut
, vol.61
, pp. 1146-1153
-
-
Kiesslich, R.1
Duckworth, C.A.2
Moussata, D.3
Gloeckner, A.4
Lim, L.G.5
Goetz, M.6
Pritchard, D.M.7
Galle, P.R.8
Neurath, M.F.9
Watson, A.J.10
-
35
-
-
34247249869
-
In-vivo microvascular imaging of early squamous-cell cancer of the esophagus by confocal laser endomicroscopy
-
Deinert K, Kiesslich R, Vieth M, Neurath MF & Neuhaus H (2007) In-vivo microvascular imaging of early squamous-cell cancer of the esophagus by confocal laser endomicroscopy. Endoscopy 39, 366–368.
-
(2007)
Endoscopy
, vol.39
, pp. 366-368
-
-
Deinert, K.1
Kiesslich, R.2
Vieth, M.3
Neurath, M.F.4
Neuhaus, H.5
-
36
-
-
79957668789
-
Redistribution of the tight junction protein ZO-1 during physiological shedding of mouse intestinal epithelial cells
-
Guan Y, Watson AJ, Marchiando AM, Bradford E, Shen L, Turner JR & Montrose MH (2011) Redistribution of the tight junction protein ZO-1 during physiological shedding of mouse intestinal epithelial cells. Am J Physiol Cell Physiol 300, C1404–C1414.
-
(2011)
Am J Physiol Cell Physiol
, vol.300
, pp. C1404-C1414
-
-
Guan, Y.1
Watson, A.J.2
Marchiando, A.M.3
Bradford, E.4
Shen, L.5
Turner, J.R.6
Montrose, M.H.7
-
37
-
-
67249099002
-
Mechanisms of epithelial cell shedding in the Mammalian intestine and maintenance of barrier function
-
Watson AJ, Duckworth CA, Guan Y & Montrose MH (2009) Mechanisms of epithelial cell shedding in the Mammalian intestine and maintenance of barrier function. Ann N Y Acad Sci 1165, 135–142.
-
(2009)
Ann N Y Acad Sci
, vol.1165
, pp. 135-142
-
-
Watson, A.J.1
Duckworth, C.A.2
Guan, Y.3
Montrose, M.H.4
-
38
-
-
0025286406
-
Maintenance of the macromolecular barrier at cell extrusion sites in intestinal epithelium: physiological rearrangement of tight junctions
-
Madara JL (1990) Maintenance of the macromolecular barrier at cell extrusion sites in intestinal epithelium: physiological rearrangement of tight junctions. J Membr Biol 116, 177–184.
-
(1990)
J Membr Biol
, vol.116
, pp. 177-184
-
-
Madara, J.L.1
-
39
-
-
84862873626
-
TNF-alpha-induced intestinal epithelial cell shedding: implications for intestinal barrier function
-
Watson AJ & Hughes KR (2012) TNF-alpha-induced intestinal epithelial cell shedding: implications for intestinal barrier function. Ann N Y Acad Sci 1258, 1–8.
-
(2012)
Ann N Y Acad Sci
, vol.1258
, pp. 1-8
-
-
Watson, A.J.1
Hughes, K.R.2
-
40
-
-
24144465134
-
Epithelial barrier function in vivo is sustained despite gaps in epithelial layers
-
Watson AJ, Chu S, Sieck L, Gerasimenko O, Bullen T, Campbell F, McKenna M, Rose T & Montrose MH (2005) Epithelial barrier function in vivo is sustained despite gaps in epithelial layers. Gastroenterology 129, 902–912.
-
(2005)
Gastroenterology
, vol.129
, pp. 902-912
-
-
Watson, A.J.1
Chu, S.2
Sieck, L.3
Gerasimenko, O.4
Bullen, T.5
Campbell, F.6
McKenna, M.7
Rose, T.8
Montrose, M.H.9
-
41
-
-
84857812550
-
Occludin is required for apoptosis when claudin-claudin interactions are disrupted
-
Beeman N, Webb PG & Baumgartner HK (2012) Occludin is required for apoptosis when claudin-claudin interactions are disrupted. Cell Death Dis 3, e273.
-
(2012)
Cell Death Dis
, vol.3
-
-
Beeman, N.1
Webb, P.G.2
Baumgartner, H.K.3
-
42
-
-
33748882013
-
Characterization of epithelial cell shedding from human small intestine
-
Bullen TF, Forrest S, Campbell F, Dodson AR, Hershman MJ, Pritchard DM, Turner JR, Montrose MH & Watson AJ (2006) Characterization of epithelial cell shedding from human small intestine. Lab Invest 86, 1052–1063.
-
(2006)
Lab Invest
, vol.86
, pp. 1052-1063
-
-
Bullen, T.F.1
Forrest, S.2
Campbell, F.3
Dodson, A.R.4
Hershman, M.J.5
Pritchard, D.M.6
Turner, J.R.7
Montrose, M.H.8
Watson, A.J.9
-
43
-
-
79953174256
-
The epithelial barrier is maintained by in vivo tight junction expansion during pathologic intestinal epithelial shedding
-
e1–2
-
Marchiando AM, Shen L, Graham WV, Edelblum KL, Duckworth CA, Guan Y, Montrose MH, Turner JR & Watson AJ (2011) The epithelial barrier is maintained by in vivo tight junction expansion during pathologic intestinal epithelial shedding. Gastroenterology 140, 1208–1218, e1–2.
-
(2011)
Gastroenterology
, vol.140
, pp. 1208-1218
-
-
Marchiando, A.M.1
Shen, L.2
Graham, W.V.3
Edelblum, K.L.4
Duckworth, C.A.5
Guan, Y.6
Montrose, M.H.7
Turner, J.R.8
Watson, A.J.9
-
44
-
-
84888350435
-
Suppression of anoikis in human intestinal epithelial cells: differentiation state-selective roles of alpha2beta1, alpha3beta1, alpha5beta1, and alpha6beta4 integrins
-
Beausejour M, Thibodeau S, Demers MJ, Bouchard V, Gauthier R, Beaulieu JF & Vachon PH (2013) Suppression of anoikis in human intestinal epithelial cells: differentiation state-selective roles of alpha2beta1, alpha3beta1, alpha5beta1, and alpha6beta4 integrins. BMC Cell Biol 14, 53.
-
(2013)
BMC Cell Biol
, vol.14
, pp. 53
-
-
Beausejour, M.1
Thibodeau, S.2
Demers, M.J.3
Bouchard, V.4
Gauthier, R.5
Beaulieu, J.F.6
Vachon, P.H.7
-
45
-
-
0034241540
-
Apoptosis: implications for inflammatory bowel disease
-
Levine AD (2000) Apoptosis: implications for inflammatory bowel disease. Inflamm Bowel Dis 6, 191–205.
-
(2000)
Inflamm Bowel Dis
, vol.6
, pp. 191-205
-
-
Levine, A.D.1
-
46
-
-
84901035061
-
Ex vivo culture of intestinal crypt organoids as a model system for assessing cell death induction in intestinal epithelial cells and enteropathy
-
Grabinger T, Luks L, Kostadinova F, Zimberlin C, Medema JP, Leist M & Brunner T (2014) Ex vivo culture of intestinal crypt organoids as a model system for assessing cell death induction in intestinal epithelial cells and enteropathy. Cell Death Dis 5, e1228.
-
(2014)
Cell Death Dis
, vol.5
-
-
Grabinger, T.1
Luks, L.2
Kostadinova, F.3
Zimberlin, C.4
Medema, J.P.5
Leist, M.6
Brunner, T.7
-
47
-
-
84887621878
-
Anoikis molecular pathways and its role in cancer progression
-
Paoli P, Giannoni E & Chiarugi P (2013) Anoikis molecular pathways and its role in cancer progression. Biochim Biophys Acta 1833, 3481–3498.
-
(2013)
Biochim Biophys Acta
, vol.1833
, pp. 3481-3498
-
-
Paoli, P.1
Giannoni, E.2
Chiarugi, P.3
-
48
-
-
0035823238
-
Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis
-
Puthalakath H, Villunger A, O'Reilly LA, Beaumont JG, Coultas L, Cheney RE, Huang DC & Strasser A (2001) Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis. Science 293, 1829–1832.
-
(2001)
Science
, vol.293
, pp. 1829-1832
-
-
Puthalakath, H.1
Villunger, A.2
O'Reilly, L.A.3
Beaumont, J.G.4
Coultas, L.5
Cheney, R.E.6
Huang, D.C.7
Strasser, A.8
-
49
-
-
0042696985
-
Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis
-
Reginato MJ, Mills KR, Paulus JK, Lynch DK, Sgroi DC, Debnath J, Muthuswamy SK & Brugge JS (2003) Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis. Nat Cell Biol 5, 733–740.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 733-740
-
-
Reginato, M.J.1
Mills, K.R.2
Paulus, J.K.3
Lynch, D.K.4
Sgroi, D.C.5
Debnath, J.6
Muthuswamy, S.K.7
Brugge, J.S.8
-
50
-
-
0032958653
-
TNF-induced enterocyte apoptosis and detachment in mice: induction of caspases and prevention by a caspase inhibitor, ZVAD-fmk
-
Piguet PF, Vesin C, Donati Y & Barazzone C (1999) TNF-induced enterocyte apoptosis and detachment in mice: induction of caspases and prevention by a caspase inhibitor, ZVAD-fmk. Lab Invest 79, 495–500.
-
(1999)
Lab Invest
, vol.79
, pp. 495-500
-
-
Piguet, P.F.1
Vesin, C.2
Donati, Y.3
Barazzone, C.4
-
52
-
-
79958698544
-
Synergistic induction of cell death in liver tumor cells by TRAIL and chemotherapeutic drugs via the BH3-only proteins Bim and Bid
-
Schneider-Jakob S, Corazza N, Badmann A, Sidler D, Stuber-Roos R, Keogh A, Frese S, Tschan M & Brunner T (2010) Synergistic induction of cell death in liver tumor cells by TRAIL and chemotherapeutic drugs via the BH3-only proteins Bim and Bid. Cell Death Dis 1, e86.
-
(2010)
Cell Death Dis
, vol.1
-
-
Schneider-Jakob, S.1
Corazza, N.2
Badmann, A.3
Sidler, D.4
Stuber-Roos, R.5
Keogh, A.6
Frese, S.7
Tschan, M.8
Brunner, T.9
-
53
-
-
0347991868
-
Bax is required for resection-induced changes in apoptosis, proliferation, and members of the extrinsic cell death pathways
-
Tang Y, Swartz-Basile DA, Swietlicki EA, Yi L, Rubin DC & Levin MS (2004) Bax is required for resection-induced changes in apoptosis, proliferation, and members of the extrinsic cell death pathways. Gastroenterology 126, 220–230.
-
(2004)
Gastroenterology
, vol.126
, pp. 220-230
-
-
Tang, Y.1
Swartz-Basile, D.A.2
Swietlicki, E.A.3
Yi, L.4
Rubin, D.C.5
Levin, M.S.6
-
54
-
-
37549048249
-
The BCL-2 protein family: opposing activities that mediate cell death
-
Youle RJ & Strasser A (2008) The BCL-2 protein family: opposing activities that mediate cell death. Nat Rev Mol Cell Biol 9, 47–59.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 47-59
-
-
Youle, R.J.1
Strasser, A.2
-
55
-
-
0032146987
-
Bcl-2-family proteins: the role of the BH3 domain in apoptosis
-
Kelekar A & Thompson CB (1998) Bcl-2-family proteins: the role of the BH3 domain in apoptosis. Trends Cell Biol 8, 324–330.
-
(1998)
Trends Cell Biol
, vol.8
, pp. 324-330
-
-
Kelekar, A.1
Thompson, C.B.2
-
56
-
-
79952700828
-
Bcl-2 proteins and mitochondria–specificity in membrane targeting for death
-
Lindsay J, Esposti MD & Gilmore AP (2011) Bcl-2 proteins and mitochondria–specificity in membrane targeting for death. Biochim Biophys Acta 1813, 532–539.
-
(2011)
Biochim Biophys Acta
, vol.1813
, pp. 532-539
-
-
Lindsay, J.1
Esposti, M.D.2
Gilmore, A.P.3
-
57
-
-
0029048596
-
Differential expression of bcl-2 in intestinal epithelia. Correlation with attenuation of apoptosis in colonic crypts and the incidence of colonic neoplasia
-
Merritt AJ, Potten CS, Watson AJ, Loh DY, Nakayama K, Nakayama K & Hickman JA (1995) Differential expression of bcl-2 in intestinal epithelia. Correlation with attenuation of apoptosis in colonic crypts and the incidence of colonic neoplasia. J Cell Sci 108 (Pt 6), 2261–2271.
-
(1995)
J Cell Sci
, vol.108
, pp. 2261-2271
-
-
Merritt, A.J.1
Potten, C.S.2
Watson, A.J.3
Loh, D.Y.4
Nakayama, K.5
Nakayama, K.6
Hickman, J.A.7
-
58
-
-
0037418843
-
BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis
-
Scorrano L, Oakes SA, Opferman JT, Cheng EH, Sorcinelli MD, Pozzan T & Korsmeyer SJ (2003) BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis. Science 300, 135–139.
-
(2003)
Science
, vol.300
, pp. 135-139
-
-
Scorrano, L.1
Oakes, S.A.2
Opferman, J.T.3
Cheng, E.H.4
Sorcinelli, M.D.5
Pozzan, T.6
Korsmeyer, S.J.7
-
59
-
-
79960683426
-
BCL-2 modifying factor (BMF) is a central regulator of anoikis in human intestinal epithelial cells
-
Hausmann M, Leucht K, Ploner C, Kiessling S, Villunger A, Becker H, Hofmann C, Falk W, Krebs M, Kellermeier S et al. (2011) BCL-2 modifying factor (BMF) is a central regulator of anoikis in human intestinal epithelial cells. J Biol Chem 286, 26533–26540.
-
(2011)
J Biol Chem
, vol.286
, pp. 26533-26540
-
-
Hausmann, M.1
Leucht, K.2
Ploner, C.3
Kiessling, S.4
Villunger, A.5
Becker, H.6
Hofmann, C.7
Falk, W.8
Krebs, M.9
Kellermeier, S.10
-
60
-
-
0034678411
-
Activated Ras prevents downregulation of Bcl-X(L) triggered by detachment from the extracellular matrix. A mechanism of Ras-induced resistance to anoikis in intestinal epithelial cells
-
Rosen K, Rak J, Leung T, Dean NM, Kerbel RS & Filmus J (2000) Activated Ras prevents downregulation of Bcl-X(L) triggered by detachment from the extracellular matrix. A mechanism of Ras-induced resistance to anoikis in intestinal epithelial cells. J Cell Biol 149, 447–456.
-
(2000)
J Cell Biol
, vol.149
, pp. 447-456
-
-
Rosen, K.1
Rak, J.2
Leung, T.3
Dean, N.M.4
Kerbel, R.S.5
Filmus, J.6
-
61
-
-
0034658350
-
Apoptotic protease activating factor 1 (Apaf-1)-independent cell death suppression by Bcl-2
-
Haraguchi M, Torii S, Matsuzawa S, Xie Z, Kitada S, Krajewski S, Yoshida H, Mak TW & Reed JC (2000) Apoptotic protease activating factor 1 (Apaf-1)-independent cell death suppression by Bcl-2. J Exp Med 191, 1709–1720.
-
(2000)
J Exp Med
, vol.191
, pp. 1709-1720
-
-
Haraguchi, M.1
Torii, S.2
Matsuzawa, S.3
Xie, Z.4
Kitada, S.5
Krajewski, S.6
Yoshida, H.7
Mak, T.W.8
Reed, J.C.9
-
62
-
-
77956908962
-
Regulation of the Apaf-1-caspase-9 apoptosome
-
Bratton SB & Salvesen GS (2010) Regulation of the Apaf-1-caspase-9 apoptosome. J Cell Sci 123, 3209–3214.
-
(2010)
J Cell Sci
, vol.123
, pp. 3209-3214
-
-
Bratton, S.B.1
Salvesen, G.S.2
-
63
-
-
27644505459
-
Formation of apoptosome is initiated by cytochrome c-induced dATP hydrolysis and subsequent nucleotide exchange on Apaf-1
-
Kim HE, Du F, Fang M & Wang X (2005) Formation of apoptosome is initiated by cytochrome c-induced dATP hydrolysis and subsequent nucleotide exchange on Apaf-1. Proc Natl Acad Sci USA 102, 17545–17550.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 17545-17550
-
-
Kim, H.E.1
Du, F.2
Fang, M.3
Wang, X.4
-
64
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, Alnemri ES & Wang X (1997) Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91, 479–489.
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
Srinivasula, S.M.4
Ahmad, M.5
Alnemri, E.S.6
Wang, X.7
-
66
-
-
0035809182
-
Matrix attachment regulates Fas-induced apoptosis in endothelial cells: a role for c-flip and implications for anoikis
-
Aoudjit F & Vuori K (2001) Matrix attachment regulates Fas-induced apoptosis in endothelial cells: a role for c-flip and implications for anoikis. J Cell Biol 152, 633–643.
-
(2001)
J Cell Biol
, vol.152
, pp. 633-643
-
-
Aoudjit, F.1
Vuori, K.2
-
67
-
-
0033598145
-
Involvement of FADD and caspase-8 signalling in detachment-induced apoptosis
-
Rytomaa M, Martins LM & Downward J (1999) Involvement of FADD and caspase-8 signalling in detachment-induced apoptosis. Curr Biol 9, 1043–1046.
-
(1999)
Curr Biol
, vol.9
, pp. 1043-1046
-
-
Rytomaa, M.1
Martins, L.M.2
Downward, J.3
-
68
-
-
0037273852
-
Protein-based therapeutic approaches targeting death receptors
-
French LE & Tschopp J (2003) Protein-based therapeutic approaches targeting death receptors. Cell Death Differ 10, 117–123.
-
(2003)
Cell Death Differ
, vol.10
, pp. 117-123
-
-
French, L.E.1
Tschopp, J.2
-
70
-
-
0032575714
-
Death receptors: signaling and modulation
-
Ashkenazi A & Dixit VM (1998) Death receptors: signaling and modulation. Science 281, 1305–1308.
-
(1998)
Science
, vol.281
, pp. 1305-1308
-
-
Ashkenazi, A.1
Dixit, V.M.2
-
71
-
-
84856764253
-
Regulation of CD95/Fas signaling at the DISC
-
Lavrik IN & Krammer PH (2012) Regulation of CD95/Fas signaling at the DISC. Cell Death Differ 19, 36–41.
-
(2012)
Cell Death Differ
, vol.19
, pp. 36-41
-
-
Lavrik, I.N.1
Krammer, P.H.2
-
72
-
-
85047692516
-
Signalling pathways of the TNF superfamily: a double-edged sword
-
Aggarwal BB (2003) Signalling pathways of the TNF superfamily: a double-edged sword. Nat Rev Immunol 3, 745–756.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 745-756
-
-
Aggarwal, B.B.1
-
73
-
-
0032101371
-
Death-effector filaments: novel cytoplasmic structures that recruit caspases and trigger apoptosis
-
Siegel RM, Martin DA, Zheng L, Ng SY, Bertin J, Cohen J & Lenardo MJ (1998) Death-effector filaments: novel cytoplasmic structures that recruit caspases and trigger apoptosis. J Cell Biol 141, 1243–1253.
-
(1998)
J Cell Biol
, vol.141
, pp. 1243-1253
-
-
Siegel, R.M.1
Martin, D.A.2
Zheng, L.3
Ng, S.Y.4
Bertin, J.5
Cohen, J.6
Lenardo, M.J.7
-
74
-
-
84864318803
-
A death effector domain chain DISC model reveals a crucial role for caspase-8 chain assembly in mediating apoptotic cell death
-
Dickens LS, Boyd RS, Jukes-Jones R, Hughes MA, Robinson GL, Fairall L, Schwabe JW, Cain K & Macfarlane M (2012) A death effector domain chain DISC model reveals a crucial role for caspase-8 chain assembly in mediating apoptotic cell death. Mol Cell 47, 291–305.
-
(2012)
Mol Cell
, vol.47
, pp. 291-305
-
-
Dickens, L.S.1
Boyd, R.S.2
Jukes-Jones, R.3
Hughes, M.A.4
Robinson, G.L.5
Fairall, L.6
Schwabe, J.W.7
Cain, K.8
Macfarlane, M.9
-
75
-
-
84864294821
-
Stoichiometry of the CD95 death-inducing signaling complex: experimental and modeling evidence for a death effector domain chain model
-
Schleich K, Warnken U, Fricker N, Ozturk S, Richter P, Kammerer K, Schnolzer M, Krammer PH & Lavrik IN (2012) Stoichiometry of the CD95 death-inducing signaling complex: experimental and modeling evidence for a death effector domain chain model. Mol Cell 47, 306–319.
-
(2012)
Mol Cell
, vol.47
, pp. 306-319
-
-
Schleich, K.1
Warnken, U.2
Fricker, N.3
Ozturk, S.4
Richter, P.5
Kammerer, K.6
Schnolzer, M.7
Krammer, P.H.8
Lavrik, I.N.9
-
76
-
-
33344476184
-
cFLIP regulation of lymphocyte activation and development
-
Budd RC, Yeh WC & Tschopp J (2006) cFLIP regulation of lymphocyte activation and development. Nat Rev Immunol 6, 196–204.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 196-204
-
-
Budd, R.C.1
Yeh, W.C.2
Tschopp, J.3
-
77
-
-
84871495233
-
c-FLIP maintains tissue homeostasis by preventing apoptosis and programmed necrosis
-
Piao X, Komazawa-Sakon S, Nishina T, Koike M, Piao JH, Ehlken H, Kurihara H, Hara M, Van Rooijen N, Schutz G et al. (2012) c-FLIP maintains tissue homeostasis by preventing apoptosis and programmed necrosis. Sci Signal 5, ra93.
-
(2012)
Sci Signal
, vol.5
, pp. 93
-
-
Piao, X.1
Komazawa-Sakon, S.2
Nishina, T.3
Koike, M.4
Piao, J.H.5
Ehlken, H.6
Kurihara, H.7
Hara, M.8
Van Rooijen, N.9
Schutz, G.10
-
78
-
-
84879837232
-
ERK controls epithelial cell death receptor signalling and cellular FLICE-like inhibitory protein (c-FLIP) in ulcerative colitis
-
Seidelin JB, Coskun M, Vainer B, Riis L, Soendergaard C & Nielsen OH (2013) ERK controls epithelial cell death receptor signalling and cellular FLICE-like inhibitory protein (c-FLIP) in ulcerative colitis. J Mol Med (Berl) 91, 839–849.
-
(2013)
J Mol Med (Berl)
, vol.91
, pp. 839-849
-
-
Seidelin, J.B.1
Coskun, M.2
Vainer, B.3
Riis, L.4
Soendergaard, C.5
Nielsen, O.H.6
-
79
-
-
84904088078
-
Tumour necrosis factor superfamily members in the pathogenesis of inflammatory bowel disease
-
Slebioda TJ & Kmiec Z (2014) Tumour necrosis factor superfamily members in the pathogenesis of inflammatory bowel disease. Mediators Inflamm 2014, 325129.
-
(2014)
Mediators Inflamm
, vol.2014
, pp. 325129
-
-
Slebioda, T.J.1
Kmiec, Z.2
-
80
-
-
83855162827
-
Differential expression of the TL1A/DcR3 system of TNF/TNFR-like proteins in large vs. small intestinal Crohn's disease
-
Bamias G, Kaltsa G, Siakavellas SI, Gizis M, Margantinis G, Zampeli E, Vafiadis-Zoumboulis I, Michopoulos S, Daikos GL & Ladas SD (2012) Differential expression of the TL1A/DcR3 system of TNF/TNFR-like proteins in large vs. small intestinal Crohn's disease. Dig Liver Dis 44, 30–36.
-
(2012)
Dig Liver Dis
, vol.44
, pp. 30-36
-
-
Bamias, G.1
Kaltsa, G.2
Siakavellas, S.I.3
Gizis, M.4
Margantinis, G.5
Zampeli, E.6
Vafiadis-Zoumboulis, I.7
Michopoulos, S.8
Daikos, G.L.9
Ladas, S.D.10
-
81
-
-
63849290926
-
Functional characterisation of decoy receptor 3 in Crohn's disease
-
Funke B, Autschbach F, Kim S, Lasitschka F, Strauch U, Rogler G, Gdynia G, Li L, Gretz N, Macher-Goeppinger S et al. (2009) Functional characterisation of decoy receptor 3 in Crohn's disease. Gut 58, 483–491.
-
(2009)
Gut
, vol.58
, pp. 483-491
-
-
Funke, B.1
Autschbach, F.2
Kim, S.3
Lasitschka, F.4
Strauch, U.5
Rogler, G.6
Gdynia, G.7
Li, L.8
Gretz, N.9
Macher-Goeppinger, S.10
-
82
-
-
33947426526
-
The CASBAH: a searchable database of caspase substrates
-
Luthi AU & Martin SJ (2007) The CASBAH: a searchable database of caspase substrates. Cell Death Differ 14, 641–650.
-
(2007)
Cell Death Differ
, vol.14
, pp. 641-650
-
-
Luthi, A.U.1
Martin, S.J.2
-
83
-
-
51349139607
-
Executioner caspase-3 and caspase-7 are functionally distinct proteases
-
Walsh JG, Cullen SP, Sheridan C, Luthi AU, Gerner C & Martin SJ (2008) Executioner caspase-3 and caspase-7 are functionally distinct proteases. Proc Natl Acad Sci USA 105, 12815–12819.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 12815-12819
-
-
Walsh, J.G.1
Cullen, S.P.2
Sheridan, C.3
Luthi, A.U.4
Gerner, C.5
Martin, S.J.6
-
84
-
-
34547126428
-
The inhibitors of apoptosis (IAPs) as cancer targets
-
Hunter AM, LaCasse EC & Korneluk RG (2007) The inhibitors of apoptosis (IAPs) as cancer targets. Apoptosis 12, 1543–1568.
-
(2007)
Apoptosis
, vol.12
, pp. 1543-1568
-
-
Hunter, A.M.1
LaCasse, E.C.2
Korneluk, R.G.3
-
85
-
-
33645640920
-
The human anti-apoptotic proteins cIAP1 and cIAP2 bind but do not inhibit caspases
-
Eckelman BP & Salvesen GS (2006) The human anti-apoptotic proteins cIAP1 and cIAP2 bind but do not inhibit caspases. J Biol Chem 281, 3254–3260.
-
(2006)
J Biol Chem
, vol.281
, pp. 3254-3260
-
-
Eckelman, B.P.1
Salvesen, G.S.2
-
86
-
-
33845689056
-
Detachment-induced upregulation of XIAP and cIAP2 delays anoikis of intestinal epithelial cells
-
Liu Z, Li H, Wu X, Yoo BH, Yan SR, Stadnyk AW, Sasazuki T, Shirasawa S, LaCasse EC, Korneluk RG et al. (2006) Detachment-induced upregulation of XIAP and cIAP2 delays anoikis of intestinal epithelial cells. Oncogene 25, 7680–7690.
-
(2006)
Oncogene
, vol.25
, pp. 7680-7690
-
-
Liu, Z.1
Li, H.2
Wu, X.3
Yoo, B.H.4
Yan, S.R.5
Stadnyk, A.W.6
Sasazuki, T.7
Shirasawa, S.8
LaCasse, E.C.9
Korneluk, R.G.10
-
87
-
-
84861647455
-
Tumor suppressor protein kinase Chk2 is a mediator of anoikis of intestinal epithelial cells
-
Yoo BH, Berezkin A, Wang Y, Zagryazhskaya A & Rosen KV (2012) Tumor suppressor protein kinase Chk2 is a mediator of anoikis of intestinal epithelial cells. Int J Cancer 131, 357–366.
-
(2012)
Int J Cancer
, vol.131
, pp. 357-366
-
-
Yoo, B.H.1
Berezkin, A.2
Wang, Y.3
Zagryazhskaya, A.4
Rosen, K.V.5
-
88
-
-
7444238212
-
T-cell-induced mucosal damage in the intestine
-
Croitoru K & Zhou P (2004) T-cell-induced mucosal damage in the intestine. Curr Opin Gastroenterol 20, 581–586.
-
(2004)
Curr Opin Gastroenterol
, vol.20
, pp. 581-586
-
-
Croitoru, K.1
Zhou, P.2
-
89
-
-
0032005020
-
Fas ligand- mediated killing by intestinal intraepithelial lymphocytes. Participation in intestinal graft-versus-host disease
-
Lin T, Brunner T, Tietz B, Madsen J, Bonfoco E, Reaves M, Huflejt M & Green DR (1998) Fas ligand- mediated killing by intestinal intraepithelial lymphocytes. Participation in intestinal graft-versus-host disease. J Clin Invest 101, 570–577.
-
(1998)
J Clin Invest
, vol.101
, pp. 570-577
-
-
Lin, T.1
Brunner, T.2
Tietz, B.3
Madsen, J.4
Bonfoco, E.5
Reaves, M.6
Huflejt, M.7
Green, D.R.8
-
90
-
-
0025963856
-
Memory and distribution of virus-specific cytotoxic T lymphocytes (CTLs) and CTL precursors after rotavirus infection
-
Offit PA, Cunningham SL & Dudzik KI (1991) Memory and distribution of virus-specific cytotoxic T lymphocytes (CTLs) and CTL precursors after rotavirus infection. J Virol 65, 1318–1324.
-
(1991)
J Virol
, vol.65
, pp. 1318-1324
-
-
Offit, P.A.1
Cunningham, S.L.2
Dudzik, K.I.3
-
91
-
-
84899639879
-
Cytokines in inflammatory bowel disease
-
Neurath MF (2014) Cytokines in inflammatory bowel disease. Nat Rev Immunol 14, 329–342.
-
(2014)
Nat Rev Immunol
, vol.14
, pp. 329-342
-
-
Neurath, M.F.1
-
92
-
-
84860125647
-
Anti-TNF-alpha antibodies improve intestinal barrier function in Crohn's disease
-
Noth R, Stuber E, Hasler R, Nikolaus S, Kuhbacher T, Hampe J, Bewig B, Schreiber S & Arlt A (2012) Anti-TNF-alpha antibodies improve intestinal barrier function in Crohn's disease. J Crohns Colitis 6, 464–469.
-
(2012)
J Crohns Colitis
, vol.6
, pp. 464-469
-
-
Noth, R.1
Stuber, E.2
Hasler, R.3
Nikolaus, S.4
Kuhbacher, T.5
Hampe, J.6
Bewig, B.7
Schreiber, S.8
Arlt, A.9
-
93
-
-
0022437235
-
The ‘gastrointestinal syndrome’ after chemotherapy: inferences from mouse survival time, and from histologically- and clonogenically-defined cell death in intestinal crypts
-
Moore JV (1986) The ‘gastrointestinal syndrome’ after chemotherapy: inferences from mouse survival time, and from histologically- and clonogenically-defined cell death in intestinal crypts. Br J Cancer Suppl 7, 16–19.
-
(1986)
Br J Cancer Suppl
, vol.7
, pp. 16-19
-
-
Moore, J.V.1
-
94
-
-
84876308263
-
Role of p53 in anticancer drug treatment- and radiation-induced injury in normal small intestine
-
Jin S (2012) Role of p53 in anticancer drug treatment- and radiation-induced injury in normal small intestine. Cancer Biol Med 9, 1–8.
-
(2012)
Cancer Biol Med
, vol.9
, pp. 1-8
-
-
Jin, S.1
-
95
-
-
0042591173
-
Roles of growth factors in chemotherapy-induced intestinal mucosal damage repair
-
Xian CJ (2003) Roles of growth factors in chemotherapy-induced intestinal mucosal damage repair. Curr Pharm Biotechnol 4, 260–269.
-
(2003)
Curr Pharm Biotechnol
, vol.4
, pp. 260-269
-
-
Xian, C.J.1
-
96
-
-
41149094512
-
Regulation of DNA repair throughout the cell cycle
-
Branzei D & Foiani M (2008) Regulation of DNA repair throughout the cell cycle. Nat Rev Mol Cell Biol 9, 297–308.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 297-308
-
-
Branzei, D.1
Foiani, M.2
-
97
-
-
33847737716
-
DNA damage checkpoints: from initiation to recovery or adaptation
-
Bartek J & Lukas J (2007) DNA damage checkpoints: from initiation to recovery or adaptation. Curr Opin Cell Biol 19, 238–245.
-
(2007)
Curr Opin Cell Biol
, vol.19
, pp. 238-245
-
-
Bartek, J.1
Lukas, J.2
-
98
-
-
70349438994
-
Tumour suppression by p53: a role for the DNA damage response?
-
Meek DW (2009) Tumour suppression by p53: a role for the DNA damage response? Nat Rev Cancer 9, 714–723.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 714-723
-
-
Meek, D.W.1
-
100
-
-
0028301094
-
p53 dependence of early apoptotic and proliferative responses within the mouse intestinal epithelium following gamma-irradiation
-
Clarke AR, Gledhill S, Hooper ML, Bird CC & Wyllie AH (1994) p53 dependence of early apoptotic and proliferative responses within the mouse intestinal epithelium following gamma-irradiation. Oncogene 9, 1767–1773.
-
(1994)
Oncogene
, vol.9
, pp. 1767-1773
-
-
Clarke, A.R.1
Gledhill, S.2
Hooper, M.L.3
Bird, C.C.4
Wyllie, A.H.5
-
101
-
-
0028047723
-
The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice
-
Merritt AJ, Potten CS, Kemp CJ, Hickman JA, Balmain A, Lane DP & Hall PA (1994) The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice. Cancer Res 54, 614–617.
-
(1994)
Cancer Res
, vol.54
, pp. 614-617
-
-
Merritt, A.J.1
Potten, C.S.2
Kemp, C.J.3
Hickman, J.A.4
Balmain, A.5
Lane, D.P.6
Hall, P.A.7
-
102
-
-
0035265686
-
PUMA, a novel proapoptotic gene, is induced by p53
-
Nakano K & Vousden KH (2001) PUMA, a novel proapoptotic gene, is induced by p53. Mol Cell 7, 683–694.
-
(2001)
Mol Cell
, vol.7
, pp. 683-694
-
-
Nakano, K.1
Vousden, K.H.2
-
103
-
-
0034640281
-
Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
-
Oda E, Ohki R, Murasawa H, Nemoto J, Shibue T, Yamashita T, Tokino T, Taniguchi T & Tanaka N (2000) Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science 288, 1053–1058.
-
(2000)
Science
, vol.288
, pp. 1053-1058
-
-
Oda, E.1
Ohki, R.2
Murasawa, H.3
Nemoto, J.4
Shibue, T.5
Yamashita, T.6
Tokino, T.7
Taniguchi, T.8
Tanaka, N.9
-
104
-
-
28844472952
-
BH3-only proteins Puma and Bim are rate-limiting for gamma-radiation- and glucocorticoid-induced apoptosis of lymphoid cells in vivo
-
Erlacher M, Michalak EM, Kelly PN, Labi V, Niederegger H, Coultas L, Adams JM, Strasser A & Villunger A (2005) BH3-only proteins Puma and Bim are rate-limiting for gamma-radiation- and glucocorticoid-induced apoptosis of lymphoid cells in vivo. Blood 106, 4131–4138.
-
(2005)
Blood
, vol.106
, pp. 4131-4138
-
-
Erlacher, M.1
Michalak, E.M.2
Kelly, P.N.3
Labi, V.4
Niederegger, H.5
Coultas, L.6
Adams, J.M.7
Strasser, A.8
Villunger, A.9
-
105
-
-
0028883179
-
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
-
Miyashita T & Reed JC (1995) Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80, 293–299.
-
(1995)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
106
-
-
44649094568
-
p53-dependent repression of the human MCL-1 gene encoding an anti-apoptotic member of the BCL-2 family: the role of Sp1 and of basic transcription factor binding sites in the MCL-1 promoter
-
Pietrzak M & Puzianowska-Kuznicka M (2008) p53-dependent repression of the human MCL-1 gene encoding an anti-apoptotic member of the BCL-2 family: the role of Sp1 and of basic transcription factor binding sites in the MCL-1 promoter. Biol Chem 389, 383–393.
-
(2008)
Biol Chem
, vol.389
, pp. 383-393
-
-
Pietrzak, M.1
Puzianowska-Kuznicka, M.2
-
107
-
-
84858589052
-
DNA-PKCS binding to p53 on the p21WAF1/CIP1 promoter blocks transcription resulting in cell death
-
Hill R, Madureira PA, Waisman DM & Lee PW (2011) DNA-PKCS binding to p53 on the p21WAF1/CIP1 promoter blocks transcription resulting in cell death. Oncotarget 2, 1094–1108.
-
(2011)
Oncotarget
, vol.2
, pp. 1094-1108
-
-
Hill, R.1
Madureira, P.A.2
Waisman, D.M.3
Lee, P.W.4
-
108
-
-
44049095767
-
In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute
-
Michalak EM, Villunger A, Adams JM & Strasser A (2008) In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute. Cell Death Differ 15, 1019–1029.
-
(2008)
Cell Death Differ
, vol.15
, pp. 1019-1029
-
-
Michalak, E.M.1
Villunger, A.2
Adams, J.M.3
Strasser, A.4
-
109
-
-
80052120071
-
p53 and PUMA independently regulate apoptosis of intestinal epithelial cells in patients and mice with colitis
-
Dirisina R, Katzman RB, Goretsky T, Managlia E, Mittal N, Williams DB, Qiu W, Yu J, Chandel NS, Zhang L et al. (2011) p53 and PUMA independently regulate apoptosis of intestinal epithelial cells in patients and mice with colitis. Gastroenterology 141, 1036–1045.
-
(2011)
Gastroenterology
, vol.141
, pp. 1036-1045
-
-
Dirisina, R.1
Katzman, R.B.2
Goretsky, T.3
Managlia, E.4
Mittal, N.5
Williams, D.B.6
Qiu, W.7
Yu, J.8
Chandel, N.S.9
Zhang, L.10
-
110
-
-
79955501236
-
PUMA-mediated intestinal epithelial apoptosis contributes to ulcerative colitis in humans and mice
-
Qiu W, Wu B, Wang X, Buchanan ME, Regueiro MD, Hartman DJ, Schoen RE, Yu J & Zhang L (2011) PUMA-mediated intestinal epithelial apoptosis contributes to ulcerative colitis in humans and mice. J Clin Invest 121, 1722–1732.
-
(2011)
J Clin Invest
, vol.121
, pp. 1722-1732
-
-
Qiu, W.1
Wu, B.2
Wang, X.3
Buchanan, M.E.4
Regueiro, M.D.5
Hartman, D.J.6
Schoen, R.E.7
Yu, J.8
Zhang, L.9
-
111
-
-
84861987695
-
Tumor suppression by p53: fall of the triumvirate?
-
Hock AK & Vousden KH (2012) Tumor suppression by p53: fall of the triumvirate? Cell 149, 1183–1185.
-
(2012)
Cell
, vol.149
, pp. 1183-1185
-
-
Hock, A.K.1
Vousden, K.H.2
-
112
-
-
84866491630
-
p53 mediates TNF-induced epithelial cell apoptosis in IBD
-
Goretsky T, Dirisina R, Sinh P, Mittal N, Managlia E, Williams DB, Posca D, Ryu H, Katzman RB & Barrett TA (2012) p53 mediates TNF-induced epithelial cell apoptosis in IBD. Am J Pathol 181, 1306–1315.
-
(2012)
Am J Pathol
, vol.181
, pp. 1306-1315
-
-
Goretsky, T.1
Dirisina, R.2
Sinh, P.3
Mittal, N.4
Managlia, E.5
Williams, D.B.6
Posca, D.7
Ryu, H.8
Katzman, R.B.9
Barrett, T.A.10
-
113
-
-
0030812174
-
Apoptosis in small intestinal epithelial from p53-null mice: evidence for a delayed, p53-independent G2/M-associated cell death after gamma-irradiation
-
Merritt AJ, Allen TD, Potten CS & Hickman JA (1997) Apoptosis in small intestinal epithelial from p53-null mice: evidence for a delayed, p53-independent G2/M-associated cell death after gamma-irradiation. Oncogene 14, 2759–2766.
-
(1997)
Oncogene
, vol.14
, pp. 2759-2766
-
-
Merritt, A.J.1
Allen, T.D.2
Potten, C.S.3
Hickman, J.A.4
-
114
-
-
33747884339
-
DNA damage-induced cell death by apoptosis
-
Roos WP & Kaina B (2006) DNA damage-induced cell death by apoptosis. Trends Mol Med 12, 440–450.
-
(2006)
Trends Mol Med
, vol.12
, pp. 440-450
-
-
Roos, W.P.1
Kaina, B.2
-
115
-
-
2442681614
-
Dual effect of p53 on radiation sensitivity in vivo: p53 promotes hematopoietic injury, but protects from gastro-intestinal syndrome in mice
-
Komarova EA, Kondratov RV, Wang K, Christov K, Golovkina TV, Goldblum JR & Gudkov AV (2004) Dual effect of p53 on radiation sensitivity in vivo: p53 promotes hematopoietic injury, but protects from gastro-intestinal syndrome in mice. Oncogene 23, 3265–3271.
-
(2004)
Oncogene
, vol.23
, pp. 3265-3271
-
-
Komarova, E.A.1
Kondratov, R.V.2
Wang, K.3
Christov, K.4
Golovkina, T.V.5
Goldblum, J.R.6
Gudkov, A.V.7
-
116
-
-
0037384023
-
Role of intestinal epithelial apoptosis in survival
-
Husain KD & Coopersmith CM (2003) Role of intestinal epithelial apoptosis in survival. Curr Opin Crit Care 9, 159–163.
-
(2003)
Curr Opin Crit Care
, vol.9
, pp. 159-163
-
-
Husain, K.D.1
Coopersmith, C.M.2
-
117
-
-
84937773001
-
Blocking TWEAK-Fn14 interaction inhibits hematopoietic stem cell transplantation-induced intestinal cell death and reduces GvHD
-
Chopra M, Brandl A, Siegmund D, Mottok A, Schafer V, Biehl M, Kraus S, Bauerlein CA, Ritz M, Mattenheimer K et al. (2015) Blocking TWEAK-Fn14 interaction inhibits hematopoietic stem cell transplantation-induced intestinal cell death and reduces GvHD. Blood 126, 437–444.
-
(2015)
Blood
, vol.126
, pp. 437-444
-
-
Chopra, M.1
Brandl, A.2
Siegmund, D.3
Mottok, A.4
Schafer, V.5
Biehl, M.6
Kraus, S.7
Bauerlein, C.A.8
Ritz, M.9
Mattenheimer, K.10
-
118
-
-
0036073328
-
Defining the roles of perforin, Fas/FasL, and tumour necrosis factor alpha in T cell induced mucosal damage in the mouse intestine
-
Merger M, Viney JL, Borojevic R, Steele-Norwood D, Zhou P, Clark DA, Riddell R, Maric R, Podack ER & Croitoru K (2002) Defining the roles of perforin, Fas/FasL, and tumour necrosis factor alpha in T cell induced mucosal damage in the mouse intestine. Gut 51, 155–163.
-
(2002)
Gut
, vol.51
, pp. 155-163
-
-
Merger, M.1
Viney, J.L.2
Borojevic, R.3
Steele-Norwood, D.4
Zhou, P.5
Clark, D.A.6
Riddell, R.7
Maric, R.8
Podack, E.R.9
Croitoru, K.10
-
119
-
-
0035451692
-
Accumulation and activation-induced release of preformed Fas (CD95) ligand during the pathogenesis of experimental graft-versus-host disease
-
Wasem C, Frutschi C, Arnold D, Vallan C, Lin T, Green DR, Mueller C & Brunner T (2001) Accumulation and activation-induced release of preformed Fas (CD95) ligand during the pathogenesis of experimental graft-versus-host disease. J Immunol 167, 2936–2941.
-
(2001)
J Immunol
, vol.167
, pp. 2936-2941
-
-
Wasem, C.1
Frutschi, C.2
Arnold, D.3
Vallan, C.4
Lin, T.5
Green, D.R.6
Mueller, C.7
Brunner, T.8
-
120
-
-
0347993062
-
Combining Fas mutation with interleukin-2 deficiency prevents Colitis and Lupus: implicating interleukin-2 for auto-reactive T cell expansion and Fas ligand for colon epithelial cell death
-
Xiao S, Sung SS, Fu SM & Ju ST (2003) Combining Fas mutation with interleukin-2 deficiency prevents Colitis and Lupus: implicating interleukin-2 for auto-reactive T cell expansion and Fas ligand for colon epithelial cell death. J Biol Chem 278, 52730–52738.
-
(2003)
J Biol Chem
, vol.278
, pp. 52730-52738
-
-
Xiao, S.1
Sung, S.S.2
Fu, S.M.3
Ju, S.T.4
-
121
-
-
77952722978
-
CD95 is cytoprotective for intestinal epithelial cells in colitis
-
Park SM, Chen L, Zhang M, Ashton-Rickardt P, Turner JR & Peter ME (2010) CD95 is cytoprotective for intestinal epithelial cells in colitis. Inflamm Bowel Dis 16, 1063–1070.
-
(2010)
Inflamm Bowel Dis
, vol.16
, pp. 1063-1070
-
-
Park, S.M.1
Chen, L.2
Zhang, M.3
Ashton-Rickardt, P.4
Turner, J.R.5
Peter, M.E.6
-
122
-
-
84928207348
-
Fas and TRAIL ‘death receptors’ as initiators of inflammation: implications for cancer
-
Cullen SP & Martin SJ (2015) Fas and TRAIL ‘death receptors’ as initiators of inflammation: implications for cancer. Semin Cell Dev Biol 39, 26–34.
-
(2015)
Semin Cell Dev Biol
, vol.39
, pp. 26-34
-
-
Cullen, S.P.1
Martin, S.J.2
-
123
-
-
0037058931
-
Nonlymphoid Fas ligand in peptide-induced peripheral lymphocyte deletion
-
Pinkoski MJ, Droin NM, Lin T, Genestier L, Ferguson TA & Green DR (2002) Nonlymphoid Fas ligand in peptide-induced peripheral lymphocyte deletion. Proc Natl Acad Sci USA 99, 16174–16179.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 16174-16179
-
-
Pinkoski, M.J.1
Droin, N.M.2
Lin, T.3
Genestier, L.4
Ferguson, T.A.5
Green, D.R.6
-
124
-
-
0032929520
-
Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo
-
Walczak H, Miller RE, Ariail K, Gliniak B, Griffith TS, Kubin M, Chin W, Jones J, Woodward A, Le T et al. (1999) Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nat Med 5, 157–163.
-
(1999)
Nat Med
, vol.5
, pp. 157-163
-
-
Walczak, H.1
Miller, R.E.2
Ariail, K.3
Gliniak, B.4
Griffith, T.S.5
Kubin, M.6
Chin, W.7
Jones, J.8
Woodward, A.9
Le, T.10
-
125
-
-
45749098451
-
To kill a tumor cell: the potential of proapoptotic receptor agonists
-
Ashkenazi A & Herbst RS (2008) To kill a tumor cell: the potential of proapoptotic receptor agonists. J Clin Invest 118, 1979–1990.
-
(2008)
J Clin Invest
, vol.118
, pp. 1979-1990
-
-
Ashkenazi, A.1
Herbst, R.S.2
-
126
-
-
84928080746
-
Cancer cell-autonomous TRAIL-R signaling promotes KRAS-driven cancer progression, invasion, and metastasis
-
von Karstedt S, Conti A, Nobis M, Montinaro A, Hartwig T, Lemke J, Legler K, Annewanter F, Campbell AD, Taraborrelli L et al. (2015) Cancer cell-autonomous TRAIL-R signaling promotes KRAS-driven cancer progression, invasion, and metastasis. Cancer Cell 27, 561–573.
-
(2015)
Cancer Cell
, vol.27
, pp. 561-573
-
-
von Karstedt, S.1
Conti, A.2
Nobis, M.3
Montinaro, A.4
Hartwig, T.5
Lemke, J.6
Legler, K.7
Annewanter, F.8
Campbell, A.D.9
Taraborrelli, L.10
-
127
-
-
33748316625
-
TRAIL receptor-mediated JNK activation and Bim phosphorylation critically regulate Fas-mediated liver damage and lethality
-
Corazza N, Jakob S, Schaer C, Frese S, Keogh A, Stroka D, Kassahn D, Torgler R, Mueller C, Schneider P et al. (2006) TRAIL receptor-mediated JNK activation and Bim phosphorylation critically regulate Fas-mediated liver damage and lethality. J Clin Invest 116, 2493–2499.
-
(2006)
J Clin Invest
, vol.116
, pp. 2493-2499
-
-
Corazza, N.1
Jakob, S.2
Schaer, C.3
Frese, S.4
Keogh, A.5
Stroka, D.6
Kassahn, D.7
Torgler, R.8
Mueller, C.9
Schneider, P.10
-
128
-
-
69149092108
-
TRAIL-induced apoptosis: between tumor therapy and immunopathology
-
Corazza N, Kassahn D, Jakob S, Badmann A & Brunner T (2009) TRAIL-induced apoptosis: between tumor therapy and immunopathology. Ann N Y Acad Sci 1171, 50–58.
-
(2009)
Ann N Y Acad Sci
, vol.1171
, pp. 50-58
-
-
Corazza, N.1
Kassahn, D.2
Jakob, S.3
Badmann, A.4
Brunner, T.5
-
129
-
-
0036179391
-
TRAIL and its receptors in the colonic epithelium: a putative role in the defense of viral infections
-
Strater J, Walczak H, Pukrop T, Von Muller L, Hasel C, Kornmann M, Mertens T & Moller P (2002) TRAIL and its receptors in the colonic epithelium: a putative role in the defense of viral infections. Gastroenterology 122, 659–666.
-
(2002)
Gastroenterology
, vol.122
, pp. 659-666
-
-
Strater, J.1
Walczak, H.2
Pukrop, T.3
Von Muller, L.4
Hasel, C.5
Kornmann, M.6
Mertens, T.7
Moller, P.8
-
130
-
-
73649099092
-
Differential expression of the TRAIL/TRAIL-receptor system in patients with inflammatory bowel disease
-
Brost S, Koschny R, Sykora J, Stremmel W, Lasitschka F, Walczak H & Ganten TM (2010) Differential expression of the TRAIL/TRAIL-receptor system in patients with inflammatory bowel disease. Pathol Res Pract 206, 43–50.
-
(2010)
Pathol Res Pract
, vol.206
, pp. 43-50
-
-
Brost, S.1
Koschny, R.2
Sykora, J.3
Stremmel, W.4
Lasitschka, F.5
Walczak, H.6
Ganten, T.M.7
-
131
-
-
58149262908
-
Fatal hepatitis mediated by tumor necrosis factor TNFalpha requires caspase-8 and involves the BH3-only proteins Bid and Bim
-
Kaufmann T, Jost PJ, Pellegrini M, Puthalakath H, Gugasyan R, Gerondakis S, Cretney E, Smyth MJ, Silke J, Hakem R et al. (2009) Fatal hepatitis mediated by tumor necrosis factor TNFalpha requires caspase-8 and involves the BH3-only proteins Bid and Bim. Immunity 30, 56–66.
-
(2009)
Immunity
, vol.30
, pp. 56-66
-
-
Kaufmann, T.1
Jost, P.J.2
Pellegrini, M.3
Puthalakath, H.4
Gugasyan, R.5
Gerondakis, S.6
Cretney, E.7
Smyth, M.J.8
Silke, J.9
Hakem, R.10
-
132
-
-
84871678939
-
Opposite role of tumor necrosis factor receptors in dextran sulfate sodium-induced colitis in mice
-
Wang K, Han G, Dou Y, Wang Y, Liu G, Wang R, Xiao H, Li X, Hou C, Shen B et al. (2012) Opposite role of tumor necrosis factor receptors in dextran sulfate sodium-induced colitis in mice. PLoS One 7, e52924.
-
(2012)
PLoS One
, vol.7
-
-
Wang, K.1
Han, G.2
Dou, Y.3
Wang, Y.4
Liu, G.5
Wang, R.6
Xiao, H.7
Li, X.8
Hou, C.9
Shen, B.10
-
133
-
-
0033571441
-
Nonlymphocyte-derived tumor necrosis factor is required for induction of colitis in recombination activating gene (RAG)2(-/-) mice upon transfer of CD4(+)CD45RB(hi) T cells
-
Corazza N, Eichenberger S, Eugster HP & Mueller C (1999) Nonlymphocyte-derived tumor necrosis factor is required for induction of colitis in recombination activating gene (RAG)2(-/-) mice upon transfer of CD4(+)CD45RB(hi) T cells. J Exp Med 190, 1479–1492.
-
(1999)
J Exp Med
, vol.190
, pp. 1479-1492
-
-
Corazza, N.1
Eichenberger, S.2
Eugster, H.P.3
Mueller, C.4
-
134
-
-
35348982262
-
Mouse models of inflammatory bowel disease
-
Wirtz S & Neurath MF (2007) Mouse models of inflammatory bowel disease. Adv Drug Deliv Rev 59, 1073–1083.
-
(2007)
Adv Drug Deliv Rev
, vol.59
, pp. 1073-1083
-
-
Wirtz, S.1
Neurath, M.F.2
-
135
-
-
84873716991
-
Regulation of intestinal epithelial permeability by tight junctions
-
Suzuki T (2013) Regulation of intestinal epithelial permeability by tight junctions. Cell Mol Life Sci 70, 631–659.
-
(2013)
Cell Mol Life Sci
, vol.70
, pp. 631-659
-
-
Suzuki, T.1
-
136
-
-
4444341939
-
Compartmentalization of TNF receptor 1 signaling: internalized TNF receptosomes as death signaling vesicles
-
Schneider-Brachert W, Tchikov V, Neumeyer J, Jakob M, Winoto-Morbach S, Held-Feindt J, Heinrich M, Merkel O, Ehrenschwender M, Adam D et al. (2004) Compartmentalization of TNF receptor 1 signaling: internalized TNF receptosomes as death signaling vesicles. Immunity 21, 415–428.
-
(2004)
Immunity
, vol.21
, pp. 415-428
-
-
Schneider-Brachert, W.1
Tchikov, V.2
Neumeyer, J.3
Jakob, M.4
Winoto-Morbach, S.5
Held-Feindt, J.6
Heinrich, M.7
Merkel, O.8
Ehrenschwender, M.9
Adam, D.10
-
137
-
-
43049152912
-
TNF-alpha induces two distinct caspase-8 activation pathways
-
Wang L, Du F & Wang X (2008) TNF-alpha induces two distinct caspase-8 activation pathways. Cell 133, 693–703.
-
(2008)
Cell
, vol.133
, pp. 693-703
-
-
Wang, L.1
Du, F.2
Wang, X.3
-
138
-
-
0041853690
-
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
-
Micheau O & Tschopp J (2003) Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 114, 181–190.
-
(2003)
Cell
, vol.114
, pp. 181-190
-
-
Micheau, O.1
Tschopp, J.2
-
139
-
-
0033592470
-
NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP
-
Sun C, Cai M, Gunasekera AH, Meadows RP, Wang H, Chen J, Zhang H, Wu W, Xu N, Ng SC et al. (1999) NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP. Nature 401, 818–822.
-
(1999)
Nature
, vol.401
, pp. 818-822
-
-
Sun, C.1
Cai, M.2
Gunasekera, A.H.3
Meadows, R.P.4
Wang, H.5
Chen, J.6
Zhang, H.7
Wu, W.8
Xu, N.9
Ng, S.C.10
-
140
-
-
71149105333
-
Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction
-
Haas TL, Emmerich CH, Gerlach B, Schmukle AC, Cordier SM, Rieser E, Feltham R, Vince J, Warnken U, Wenger T et al. (2009) Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction. Mol Cell 36, 831–844.
-
(2009)
Mol Cell
, vol.36
, pp. 831-844
-
-
Haas, T.L.1
Emmerich, C.H.2
Gerlach, B.3
Schmukle, A.C.4
Cordier, S.M.5
Rieser, E.6
Feltham, R.7
Vince, J.8
Warnken, U.9
Wenger, T.10
-
141
-
-
1342285692
-
Tumor necrosis factor: an apoptosis JuNKie?
-
Varfolomeev EE & Ashkenazi A (2004) Tumor necrosis factor: an apoptosis JuNKie? Cell 116, 491–497.
-
(2004)
Cell
, vol.116
, pp. 491-497
-
-
Varfolomeev, E.E.1
Ashkenazi, A.2
-
142
-
-
80054842204
-
Constitutive intestinal NF-kappaB does not trigger destructive inflammation unless accompanied by MAPK activation
-
Guma M, Stepniak D, Shaked H, Spehlmann ME, Shenouda S, Cheroutre H, Vicente-Suarez I, Eckmann L, Kagnoff MF & Karin M (2011) Constitutive intestinal NF-kappaB does not trigger destructive inflammation unless accompanied by MAPK activation. J Exp Med 208, 1889–1900.
-
(2011)
J Exp Med
, vol.208
, pp. 1889-1900
-
-
Guma, M.1
Stepniak, D.2
Shaked, H.3
Spehlmann, M.E.4
Shenouda, S.5
Cheroutre, H.6
Vicente-Suarez, I.7
Eckmann, L.8
Kagnoff, M.F.9
Karin, M.10
-
143
-
-
33646349207
-
Wound-induced p38MAPK-dependent histone H3 phosphorylation correlates with increased COX-2 expression in enterocytes
-
Karrasch T, Steinbrecher KA, Allard B, Baldwin AS & Jobin C (2006) Wound-induced p38MAPK-dependent histone H3 phosphorylation correlates with increased COX-2 expression in enterocytes. J Cell Physiol 207, 809–815.
-
(2006)
J Cell Physiol
, vol.207
, pp. 809-815
-
-
Karrasch, T.1
Steinbrecher, K.A.2
Allard, B.3
Baldwin, A.S.4
Jobin, C.5
-
144
-
-
17944371991
-
The intriguing biology of the tumour necrosis factor/tumour necrosis factor receptor superfamily: players, rules and the games
-
Hehlgans T & Pfeffer K (2005) The intriguing biology of the tumour necrosis factor/tumour necrosis factor receptor superfamily: players, rules and the games. Immunology 115, 1–20.
-
(2005)
Immunology
, vol.115
, pp. 1-20
-
-
Hehlgans, T.1
Pfeffer, K.2
-
145
-
-
79955113861
-
Intestinal epithelial cells as producers but not targets of chronic TNF suffice to cause murine Crohn-like pathology
-
Roulis M, Armaka M, Manoloukos M, Apostolaki M & Kollias G (2011) Intestinal epithelial cells as producers but not targets of chronic TNF suffice to cause murine Crohn-like pathology. Proc Natl Acad Sci USA 108, 5396–5401.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 5396-5401
-
-
Roulis, M.1
Armaka, M.2
Manoloukos, M.3
Apostolaki, M.4
Kollias, G.5
-
146
-
-
36448986035
-
Upregulation of cIAP2 in regenerating colonocytes in ulcerative colitis
-
Seidelin JB, Vainer B, Andresen L & Nielsen OH (2007) Upregulation of cIAP2 in regenerating colonocytes in ulcerative colitis. Virchows Arch 451, 1031–1038.
-
(2007)
Virchows Arch
, vol.451
, pp. 1031-1038
-
-
Seidelin, J.B.1
Vainer, B.2
Andresen, L.3
Nielsen, O.H.4
-
147
-
-
55549107524
-
CD95 stimulation results in the formation of a novel death effector domain protein-containing complex
-
Lavrik IN, Mock T, Golks A, Hoffmann JC, Baumann S & Krammer PH (2008) CD95 stimulation results in the formation of a novel death effector domain protein-containing complex. J Biol Chem 283, 26401–26408.
-
(2008)
J Biol Chem
, vol.283
, pp. 26401-26408
-
-
Lavrik, I.N.1
Mock, T.2
Golks, A.3
Hoffmann, J.C.4
Baumann, S.5
Krammer, P.H.6
-
148
-
-
47549097367
-
TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha
-
Vince JE, Chau D, Callus B, Wong WW, Hawkins CJ, Schneider P, McKinlay M, Benetatos CA, Condon SM, Chunduru SK et al. (2008) TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha. J Cell Biol 182, 171–184.
-
(2008)
J Cell Biol
, vol.182
, pp. 171-184
-
-
Vince, J.E.1
Chau, D.2
Callus, B.3
Wong, W.W.4
Hawkins, C.J.5
Schneider, P.6
McKinlay, M.7
Benetatos, C.A.8
Condon, S.M.9
Chunduru, S.K.10
-
149
-
-
70350007940
-
TNF-like weak inducer of apoptosis inhibits proinflammatory TNF receptor-1 signaling
-
Wicovsky A, Salzmann S, Roos C, Ehrenschwender M, Rosenthal T, Siegmund D, Henkler F, Gohlke F, Kneitz C & Wajant H (2009) TNF-like weak inducer of apoptosis inhibits proinflammatory TNF receptor-1 signaling. Cell Death Differ 16, 1445–1459.
-
(2009)
Cell Death Differ
, vol.16
, pp. 1445-1459
-
-
Wicovsky, A.1
Salzmann, S.2
Roos, C.3
Ehrenschwender, M.4
Rosenthal, T.5
Siegmund, D.6
Henkler, F.7
Gohlke, F.8
Kneitz, C.9
Wajant, H.10
-
151
-
-
77951251430
-
Necroptosis as an alternative form of programmed cell death
-
Christofferson DE & Yuan J (2010) Necroptosis as an alternative form of programmed cell death. Curr Opin Cell Biol 22, 263–268.
-
(2010)
Curr Opin Cell Biol
, vol.22
, pp. 263-268
-
-
Christofferson, D.E.1
Yuan, J.2
-
153
-
-
0037088632
-
Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3
-
Sun X, Yin J, Starovasnik MA, Fairbrother WJ & Dixit VM (2002) Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3. J Biol Chem 277, 9505–9511.
-
(2002)
J Biol Chem
, vol.277
, pp. 9505-9511
-
-
Sun, X.1
Yin, J.2
Starovasnik, M.A.3
Fairbrother, W.J.4
Dixit, V.M.5
-
155
-
-
0034743199
-
NF-kappaB signals induce the expression of c-FLIP
-
Micheau O, Lens S, Gaide O, Alevizopoulos K & Tschopp J (2001) NF-kappaB signals induce the expression of c-FLIP. Mol Cell Biol 21, 5299–5305.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 5299-5305
-
-
Micheau, O.1
Lens, S.2
Gaide, O.3
Alevizopoulos, K.4
Tschopp, J.5
-
156
-
-
77955465116
-
Model-based dissection of CD95 signaling dynamics reveals both a pro- and antiapoptotic role of c-FLIPL
-
Fricker N, Beaudouin J, Richter P, Eils R, Krammer PH & Lavrik IN (2010) Model-based dissection of CD95 signaling dynamics reveals both a pro- and antiapoptotic role of c-FLIPL. J Cell Biol 190, 377–389.
-
(2010)
J Cell Biol
, vol.190
, pp. 377-389
-
-
Fricker, N.1
Beaudouin, J.2
Richter, P.3
Eils, R.4
Krammer, P.H.5
Lavrik, I.N.6
-
157
-
-
0035827569
-
Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex
-
Krueger A, Schmitz I, Baumann S, Krammer PH & Kirchhoff S (2001) Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex. J Biol Chem 276, 20633–20640.
-
(2001)
J Biol Chem
, vol.276
, pp. 20633-20640
-
-
Krueger, A.1
Schmitz, I.2
Baumann, S.3
Krammer, P.H.4
Kirchhoff, S.5
-
158
-
-
32044447161
-
The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover
-
Chang L, Kamata H, Solinas G, Luo JL, Maeda S, Venuprasad K, Liu YC & Karin M (2006) The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover. Cell 124, 601–613.
-
(2006)
Cell
, vol.124
, pp. 601-613
-
-
Chang, L.1
Kamata, H.2
Solinas, G.3
Luo, J.L.4
Maeda, S.5
Venuprasad, K.6
Liu, Y.C.7
Karin, M.8
-
159
-
-
81255195542
-
Programmed necrosis: backup to and competitor with apoptosis in the immune system
-
Han J, Zhong CQ & Zhang DW (2011) Programmed necrosis: backup to and competitor with apoptosis in the immune system. Nat Immunol 12, 1143–1149.
-
(2011)
Nat Immunol
, vol.12
, pp. 1143-1149
-
-
Han, J.1
Zhong, C.Q.2
Zhang, D.W.3
-
160
-
-
84907197966
-
RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis
-
Takahashi N, Vereecke L, Bertrand MJ, Duprez L, Berger SB, Divert T, Goncalves A, Sze M, Gilbert B, Kourula S et al. (2014) RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis. Nature 513, 95–99.
-
(2014)
Nature
, vol.513
, pp. 95-99
-
-
Takahashi, N.1
Vereecke, L.2
Bertrand, M.J.3
Duprez, L.4
Berger, S.B.5
Divert, T.6
Goncalves, A.7
Sze, M.8
Gilbert, B.9
Kourula, S.10
-
161
-
-
84903437759
-
Should we be treating the bugs instead of cytokines and T cells?
-
Wine E (2014) Should we be treating the bugs instead of cytokines and T cells? Dig Dis 32, 403–409.
-
(2014)
Dig Dis
, vol.32
, pp. 403-409
-
-
Wine, E.1
-
162
-
-
34548687694
-
NALP inflammasomes: a central role in innate immunity
-
Martinon F, Gaide O, Petrilli V, Mayor A & Tschopp J (2007) NALP inflammasomes: a central role in innate immunity. Semin Immunopathol 29, 213–229.
-
(2007)
Semin Immunopathol
, vol.29
, pp. 213-229
-
-
Martinon, F.1
Gaide, O.2
Petrilli, V.3
Mayor, A.4
Tschopp, J.5
-
163
-
-
84856231635
-
Viral infection and the evolution of caspase 8-regulated apoptotic and necrotic death pathways
-
Mocarski ES, Upton JW & Kaiser WJ (2012) Viral infection and the evolution of caspase 8-regulated apoptotic and necrotic death pathways. Nat Rev Immunol 12, 79–88.
-
(2012)
Nat Rev Immunol
, vol.12
, pp. 79-88
-
-
Mocarski, E.S.1
Upton, J.W.2
Kaiser, W.J.3
-
164
-
-
75649093343
-
Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function
-
Abreu MT (2010) Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function. Nat Rev Immunol 10, 131–144.
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 131-144
-
-
Abreu, M.T.1
|