Ex vivo whole-embryo culture of caspase-8-dificient embryos normalize their aberrant phenotypes in the developing neural tube and heart

Cell Death and Differentiation

Volumn 9, Issue 11, 2002, Pages 1196-1206

  Sakamaki, K ^a   Inoue, T ^b   Asano, M ^c,f   Sudo, K ^c   Kazama, H ^a   Sakagami, J ^c   Sakata, S ^a   Ozaki, M ^d   Nakamura, S ^b   Toyokuni, S ^a   Osumi, N ^c,e   Yonehara, S ^a  

^a KYOTO UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^e TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^f KANAZAWA UNIVERSITY   (Japan)

Author keywords

Angiogenesis; Apoptosis; Cardiac rupture; Caspase 8; Hemorrhage; Whole embryo culture

Indexed keywords

CASPASE 8; FAS ANTIGEN; CASP8 PROTEIN, MOUSE; CASP9 PROTEIN, MOUSE; CASPASE; CASPASE 9;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; EMBRYO; EMBRYO CULTURE; EMBRYO DEATH; EMBRYO DEVELOPMENT; EMBRYONAL TISSUE; ENZYME ACTIVITY; GENE TARGETING; GESTATIONAL AGE; HEART DEVELOPMENT; HOMOZYGOSITY; HUMAN; HUMAN CELL; IN VIVO STUDY; MOUSE; MUTANT; NEURAL TUBE; NEURAL TUBE DEFECT; NONHUMAN; PATHOPHYSIOLOGY; PHENOTYPE; PRIORITY JOURNAL; VASCULARIZATION; YOLK SAC; ANIMAL; BLOOD VESSEL; CONGENITAL MALFORMATION; ENZYMOLOGY; GENETICS; GROWTH, DEVELOPMENT AND AGING; HEART; IN VITRO STUDY; MOUSE MUTANT; PRENATAL DEVELOPMENT;

ANIMALS; BLOOD VESSELS; CASPASE 8; CASPASE 9; CASPASES; EMBRYO; GENE TARGETING; HEART; MICE; MICE, KNOCKOUT; NEURAL TUBE DEFECTS; YOLK SAC;

EID: 0036848180     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4401090     Document Type: Article

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