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Volumn 108, Issue 13, 2011, Pages 5396-5401

Intestinal epithelial cells as producers but not targets of chronic TNF suffice to cause murine Crohn-like pathology

Author keywords

Ileitis; Inflammatory bowel disease; Mesenchymal; Mucosal

Indexed keywords

GELATINASE A; GELATINASE B; INTERCELLULAR ADHESION MOLECULE 1; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR 1;

EID: 79955113861     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1007811108     Document Type: Article
Times cited : (111)

References (46)
  • 1
    • 34547176642 scopus 로고    scopus 로고
    • Unravelling the pathogenesis of inflammatory bowel disease
    • DOI 10.1038/nature06005, PII NATURE06005
    • Xavier RJ, Podolsky DK (2007) Unravelling the pathogenesis of inflammatory bowel disease. Nature 448:427-434. (Pubitemid 47123518)
    • (2007) Nature , vol.448 , Issue.7152 , pp. 427-434
    • Xavier, R.J.1    Podolsky, D.K.2
  • 2
    • 0037043658 scopus 로고    scopus 로고
    • Inflammatory bowel disease
    • DOI 10.1056/NEJMra020831
    • Podolsky DK (2002) Inflammatory bowel disease. N Engl J Med 347:417-429. (Pubitemid 34851835)
    • (2002) New England Journal of Medicine , vol.347 , Issue.6 , pp. 417-429
    • Podolsky, D.K.1
  • 3
    • 44349124113 scopus 로고    scopus 로고
    • The genetics and immunopathogenesis of inflammatory bowel disease
    • DOI 10.1038/nri2340, PII NRI2340
    • Cho JH (2008) The genetics and immunopathogenesis of inflammatory bowel disease. Nat Rev Immunol 8:458-466. (Pubitemid 351733422)
    • (2008) Nature Reviews Immunology , vol.8 , Issue.6 , pp. 458-466
    • Cho, J.H.1
  • 4
    • 0036218221 scopus 로고    scopus 로고
    • The immunology of mucosal models of inflammation
    • DOI 10.1146/annurev.immunol.20.100301.064816
    • Strober W, Fuss IJ, Blumberg RS (2002) The immunology of mucosal models of inflammation. Annu Rev Immunol 20:495-549. (Pubitemid 34293433)
    • (2002) Annual Review of Immunology , vol.20 , pp. 495-549
    • Strober, W.1    Fuss, I.J.2    Blumberg, R.S.3
  • 5
    • 0030954732 scopus 로고    scopus 로고
    • A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease
    • Crohn's Disease cA2 Study Group
    • Targan SR, et al.; Crohn's Disease cA2 Study Group (1997) A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. N Engl J Med 337:1029-1035.
    • (1997) N Engl J Med , vol.337 , pp. 1029-1035
    • Targan, S.R.1
  • 6
    • 79951501790 scopus 로고    scopus 로고
    • Cellular mechanisms of TNF function in models of inflammation and autoimmunity
    • Apostolaki M, Armaka M, Victoratos P, Kollias G (2010) Cellular mechanisms of TNF function in models of inflammation and autoimmunity. Curr Dir Autoimmun 11:1-26.
    • (2010) Curr Dir Autoimmun , vol.11 , pp. 1-26
    • Apostolaki, M.1    Armaka, M.2    Victoratos, P.3    Kollias, G.4
  • 7
    • 77952318710 scopus 로고    scopus 로고
    • TNF suppresses acute intestinal inflammation by inducing local glucocorticoid synthesis
    • Noti M, Corazza N, Mueller C, Berger B, Brunner T (2010) TNF suppresses acute intestinal inflammation by inducing local glucocorticoid synthesis. J Exp Med 207: 1057-1066.
    • (2010) J Exp Med , vol.207 , pp. 1057-1066
    • Noti, M.1    Corazza, N.2    Mueller, C.3    Berger, B.4    Brunner, T.5
  • 8
    • 76249094155 scopus 로고    scopus 로고
    • Probiotics promote gut health through stimulation of epithelial innate immunity
    • Pagnini C, et al. (2010) Probiotics promote gut health through stimulation of epithelial innate immunity. Proc Natl Acad Sci USA 107:454-459.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 454-459
    • Pagnini, C.1
  • 9
    • 0033103805 scopus 로고    scopus 로고
    • Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU- rich elements: Implications for joint and gut-associated immunopathologies
    • Kontoyiannis D, Pasparakis M, Pizarro TT, Cominelli F, Kollias G (1999) Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: Implications for joint and gut-associated immunopathologies. Immunity 10:387-398. (Pubitemid 29165293)
    • (1999) Immunity , vol.10 , Issue.3 , pp. 387-398
    • Kontoyiannis, D.1    Pasparakis, M.2    Pizarro, T.T.3    Cominelli, F.4    Kollias, G.5
  • 13
    • 44349132270 scopus 로고    scopus 로고
    • Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut
    • DOI 10.1038/nri2316, PII NRI2316
    • Artis D (2008) Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut. Nat Rev Immunol 8:411-420. (Pubitemid 351733416)
    • (2008) Nature Reviews Immunology , vol.8 , Issue.6 , pp. 411-420
    • Artis, D.1
  • 16
    • 55749096587 scopus 로고    scopus 로고
    • Innate immune signalling at intestinal mucosal surfaces: A fine line between host protection and destruction
    • Cario E (2008) Innate immune signalling at intestinal mucosal surfaces: A fine line between host protection and destruction. Curr Opin Gastroenterol 24:725-732.
    • (2008) Curr Opin Gastroenterol , vol.24 , pp. 725-732
    • Cario, E.1
  • 17
    • 56249135538 scopus 로고    scopus 로고
    • A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
    • Cadwell K, et al. (2008) A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells. Nature 456:259-263.
    • (2008) Nature , vol.456 , pp. 259-263
    • Cadwell, K.1
  • 18
    • 50449091647 scopus 로고    scopus 로고
    • Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease
    • McCarroll SA, et al. (2008) Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease. Nat Genet 40:1107-1112.
    • (2008) Nat Genet , vol.40 , pp. 1107-1112
    • McCarroll, S.A.1
  • 20
    • 56249090667 scopus 로고    scopus 로고
    • Loss of the autophagy protein Atg16L1 enhances endotoxininduced IL-1beta production
    • Saitoh T, et al. (2008) Loss of the autophagy protein Atg16L1 enhances endotoxininduced IL-1beta production. Nature 456:264-268.
    • (2008) Nature , vol.456 , pp. 264-268
    • Saitoh, T.1
  • 22
    • 34447281675 scopus 로고    scopus 로고
    • Molecular basis of epithelial barrier regulation: From basic mechanisms to clinical application
    • DOI 10.2353/ajpath.2006.060681
    • Turner JR (2006) Molecular basis of epithelial barrier regulation: From basic mechanisms to clinical application. Am J Pathol 169:1901-1909. (Pubitemid 351181952)
    • (2006) American Journal of Pathology , vol.169 , Issue.6 , pp. 1901-1909
    • Turner, J.R.1
  • 23
    • 4344700784 scopus 로고    scopus 로고
    • Downregulation of epithelial apoptosis and barrier repair in active Crohn's disease by tumour necrosis factor α antibody treatment
    • DOI 10.1136/gut.2003.036632
    • Zeissig S, et al. (2004) Downregulation of epithelial apoptosis and barrier repair in active Crohn's disease by tumour necrosis factor alpha antibody treatment. Gut 53: 1295-1302. (Pubitemid 39120115)
    • (2004) Gut , vol.53 , Issue.9 , pp. 1295-1302
    • Zeissig, S.1    Bojarski, C.2    Buergel, N.3    Mankertz, J.4    Zeitz, M.5    Fromm, M.6    Schulzke, J.D.7
  • 24
    • 0037031856 scopus 로고    scopus 로고
    • Cis elements of the villin gene control expression in restricted domains of the vertical (crypt) and horizontal (duodenum, cecum) axes of the intestine
    • DOI 10.1074/jbc.M204935200
    • Madison BB, et al. (2002) Cis elements of the villin gene control expression in restricted domains of the vertical (crypt) and horizontal (duodenum, cecum) axes of the intestine. J Biol Chem 277:33275-33283. (Pubitemid 34984848)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.36 , pp. 33275-33283
    • Madison, B.B.1    Dunbar, L.2    Qiao, X.T.3    Braunstein, K.4    Braunstein, E.5    Gumucio, D.L.6
  • 25
    • 33846180682 scopus 로고    scopus 로고
    • Matrix metalloproteinases in inflammatory bowel disease: Boon or a bane?
    • DOI 10.1002/ibd.20011
    • Ravi A, Garg P, Sitaraman SV (2007) Matrix metalloproteinases in inflammatory bowel disease: Boon or a bane? Inflamm Bowel Dis 13:97-107. (Pubitemid 46080015)
    • (2007) Inflammatory Bowel Diseases , vol.13 , Issue.1 , pp. 97-107
    • Ravi, A.1    Garg, P.2    Sitaraman, S.V.3
  • 28
    • 18844457308 scopus 로고    scopus 로고
    • ICAM-1 co-stimulates target cells to facilitate antigen presentation
    • DOI 10.1016/j.coi.2005.04.008, PII S095279150500052X, Lymphocyte Activation/Lymphocyte Effector Functions
    • Lebedeva T, Dustin ML, Sykulev Y (2005) ICAM1 co-stimulates target cells to facilitate antigen presentation. Curr Opin Immunol 17:251-258. (Pubitemid 40692659)
    • (2005) Current Opinion in Immunology , vol.17 , Issue.3 , pp. 251-258
    • Lebedeva, T.1    Dustin, M.L.2    Sykulev, Y.3
  • 29
    • 0031770767 scopus 로고    scopus 로고
    • TNF-induced enterocyte apoptosis in mice is mediated by the TNF receptor 1 and does not require p53
    • DOI 10.1002/(SICI)1521-4141(199811)28:11<3499::AID-IMMU3499>3.0. CO;2-Q
    • Piguet PF, Vesin C, Guo J, Donati Y, Barazzone C (1998) TNF-induced enterocyte apoptosis in mice is mediated by the TNF receptor 1 and does not require p53. Eur J Immunol 28:3499-3505. (Pubitemid 28510760)
    • (1998) European Journal of Immunology , vol.28 , Issue.11 , pp. 3499-3505
    • Piguet, P.F.1    Vesin, C.2    Guo, J.3    Donati, Y.4    Barazzone, C.5
  • 30
    • 30444457243 scopus 로고    scopus 로고
    • FDC-specific functions of p55TNFR and IKK2 in the development of FDC networks and of antibody responses
    • Victoratos P, et al. (2006) FDC-specific functions of p55TNFR and IKK2 in the development of FDC networks and of antibody responses. Immunity 24:65-77.
    • (2006) Immunity , vol.24 , pp. 65-77
    • Victoratos, P.1
  • 33
    • 49049095991 scopus 로고    scopus 로고
    • Enterocyte-derived TAK1 signaling prevents epithelium apoptosis and the development of ileitis and colitis
    • Kajino-Sakamoto R, et al. (2008) Enterocyte-derived TAK1 signaling prevents epithelium apoptosis and the development of ileitis and colitis. J Immunol 181: 1143-1152.
    • (2008) J Immunol , vol.181 , pp. 1143-1152
    • Kajino-Sakamoto, R.1
  • 35
    • 33645049332 scopus 로고    scopus 로고
    • The primary defect in experimental ileitis originates from a nonhematopoietic source
    • Olson TS, et al. (2006) The primary defect in experimental ileitis originates from a nonhematopoietic source. J Exp Med 203:541-552.
    • (2006) J Exp Med , vol.203 , pp. 541-552
    • Olson, T.S.1
  • 36
    • 50249086073 scopus 로고    scopus 로고
    • XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease
    • Kaser A, et al. (2008) XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease. Cell 134:743-756.
    • (2008) Cell , vol.134 , pp. 743-756
    • Kaser, A.1
  • 38
    • 77952318832 scopus 로고    scopus 로고
    • Intestinal bacteria and the regulation of immune cell homeostasis
    • Hill DA, Artis D (2010) Intestinal bacteria and the regulation of immune cell homeostasis. Annu Rev Immunol 28:623-667.
    • (2010) Annu Rev Immunol , vol.28 , pp. 623-667
    • Hill, D.A.1    Artis, D.2
  • 39
    • 0028864991 scopus 로고
    • A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion
    • Jung HC, et al. (1995) A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion. J Clin Invest 95:55-65.
    • (1995) J Clin Invest , vol.95 , pp. 55-65
    • Jung, H.C.1
  • 40
    • 77950251400 scopus 로고    scopus 로고
    • A human gut microbial gene catalogue established by metagenomic sequencing
    • MetaHIT Consortium
    • Qin J, et al.; MetaHIT Consortium (2010) A human gut microbial gene catalogue established by metagenomic sequencing. Nature 464:59-65.
    • (2010) Nature , vol.464 , pp. 59-65
    • Qin, J.1
  • 42
    • 3042845514 scopus 로고    scopus 로고
    • Activation of NK-κB in intestinal cells by E. coli strains isolated from the colonic mucosa of IBD patients
    • DOI 10.1007/s00384-004-0583-7
    • La Ferla K, Seegert D, Schreiber S (2004) Activation of NF-kappaB in intestinal epithelial cells by E. coli strains isolated from the colonic mucosa of IBD patients. Int J Colorectal Dis 19:334-342. (Pubitemid 38868299)
    • (2004) International Journal of Colorectal Disease , vol.19 , Issue.4 , pp. 334-342
    • La Ferla, K.1    Seegert, D.2    Schreiber, S.3
  • 43
    • 0033516488 scopus 로고    scopus 로고
    • Critical role of cAMP response element binding protein expression in hypoxia-elicited induction of epithelial tumor necrosis factor-alpha
    • Taylor CT, Fueki N, Agah A, Hershberg RM, Colgan SP (1999) Critical role of cAMP response element binding protein expression in hypoxia-elicited induction of epithelial tumor necrosis factor-alpha. J Biol Chem 274:19447-19454.
    • (1999) J Biol Chem , vol.274 , pp. 19447-19454
    • Taylor, C.T.1    Fueki, N.2    Agah, A.3    Hershberg, R.M.4    Colgan, S.P.5
  • 45
    • 33947706133 scopus 로고    scopus 로고
    • Role of intestinal subepithelial myofibroblasts in inflammation and regenerative response in the gut
    • DOI 10.1016/j.pharmthera.2006.12.004, PII S0163725807000137
    • Andoh A, Bamba S, Brittan M, Fujiyama Y, Wright NA (2007) Role of intestinal subepithelial myofibroblasts in inflammation and regenerative response in the gut. Pharmacol Ther 114:94-106. (Pubitemid 46498158)
    • (2007) Pharmacology and Therapeutics , vol.114 , Issue.1 , pp. 94-106
    • Andoh, A.1    Bamba, S.2    Brittan, M.3    Fujiyama, Y.4    Wright, N.A.5


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