-
1
-
-
0028273754
-
Thymus independent T cell development and selection in the intestinal epithelium
-
Poussier P, Julius M: Thymus independent T cell development and selection in the intestinal epithelium. Annu Rev Immunol 1994, 12:521-553.
-
(1994)
Annu Rev Immunol
, vol.12
, pp. 521-553
-
-
Poussier, P.1
Julius, M.2
-
2
-
-
0037415594
-
Extrathymic T cell lymphopoiesis: Ontogeny and contribution to gut intraepithelial lymphocytes in athymic and euthymic mice
-
Guy-Grand D, Azogui O, Celli S, et al.: Extrathymic T cell lymphopoiesis: ontogeny and contribution to gut intraepithelial lymphocytes in athymic and euthymic mice. J Exp Med 2003, 197:333-341.
-
(2003)
J Exp Med
, vol.197
, pp. 333-341
-
-
Guy-Grand, D.1
Azogui, O.2
Celli, S.3
-
3
-
-
0032524992
-
Activation of the CD2 pathway in lamina propria T cells up- regulates functionally active AP-1 binding to the IL-2 promoter, resulting in messenger RNA transcription and IL-2 secretion
-
Gonsky R, Deem RL, Hughes CCW, Targan SR: Activation of the CD2 pathway in lamina propria T cells up- regulates functionally active AP-1 binding to the IL-2 promoter, resulting in messenger RNA transcription and IL-2 secretion. J Immunol 1998, 160:4914-4922.
-
(1998)
J Immunol
, vol.160
, pp. 4914-4922
-
-
Gonsky, R.1
Deem, R.L.2
Hughes, C.C.W.3
Targan, S.R.4
-
4
-
-
0033485666
-
The differentiated state of intestinal lamina propria CD4+ T cells results in altered cytokine production, activation threshold, and costimulatory requirements
-
Hurst SD, Cooper CJ, Sitterding SM, et al.: The differentiated state of intestinal lamina propria CD4+ T cells results in altered cytokine production, activation threshold, and costimulatory requirements. J Immunol 1999, 163:5937-5945.
-
(1999)
J Immunol
, vol.163
, pp. 5937-5945
-
-
Hurst, S.D.1
Cooper, C.J.2
Sitterding, S.M.3
-
5
-
-
0030218844
-
Costimulation of the CD3 pathway by CD28 ligation in human intestinal lymphocytes
-
Ebert EC, Roberts AI: Costimulation of the CD3 pathway by CD28 ligation in human intestinal lymphocytes. Cell Immunol 1996, 171:211-216.
-
(1996)
Cell Immunol
, vol.171
, pp. 211-216
-
-
Ebert, E.C.1
Roberts, A.I.2
-
6
-
-
0023925510
-
Evidence that activated mucosal T cells play a role in the pathogenesis of enteropathy in human small intestine
-
MacDonald TT, Spencer J: Evidence that activated mucosal T cells play a role in the pathogenesis of enteropathy in human small intestine. J Exp Med 1988, 167:1341-1349.
-
(1988)
J Exp Med
, vol.167
, pp. 1341-1349
-
-
MacDonald, T.T.1
Spencer, J.2
-
7
-
-
0028980830
-
CD1-restricted T cell recognition of microbial lipoglycan antigens
-
Sieling PA, Chatterjee D, Porcelli SA, et al.: CD1-restricted T cell recognition of microbial lipoglycan antigens. Science 1995, 269:227-230.
-
(1995)
Science
, vol.269
, pp. 227-230
-
-
Sieling, P.A.1
Chatterjee, D.2
Porcelli, S.A.3
-
8
-
-
0031937067
-
Small bowel enteropathy: Role of intraepithelial lymphocytes and of cytokines (IL-12, IFN-gamma, TNF) in the induction of epithelial cell death and renewal
-
Guy-Grand D, DiSanto JP, Henchoz P, et al.: Small bowel enteropathy: role of intraepithelial lymphocytes and of cytokines (IL-12, IFN-gamma, TNF) in the induction of epithelial cell death and renewal. Eur J Immunol 1998, 28:730-744.
-
(1998)
Eur J Immunol
, vol.28
, pp. 730-744
-
-
Guy-Grand, D.1
DiSanto, J.P.2
Henchoz, P.3
-
9
-
-
0026464657
-
Cytokines in inflammatory bowel disease
-
Brynskov J, Nielsen OH, Ahnfelt-ronne I, Bendtzen K: Cytokines in inflammatory bowel disease. Scand J Gastroenterol 1992, 27:897-906.
-
(1992)
Scand J Gastroenterol
, vol.27
, pp. 897-906
-
-
Brynskov, J.1
Nielsen, O.H.2
Ahnfelt-ronne, I.3
Bendtzen, K.4
-
11
-
-
2442685319
-
DNA fragmentation and detachment of enterocytes induced by anti-CD3 mAb-activated intraepithelial lymphocytes
-
Yaguchi K, Kayaba S, Soga H, et al.: DNA fragmentation and detachment of enterocytes induced by anti-CD3 mAb-activated intraepithelial lymphocytes. Cell Tissue Res 2004, 315:71-84. An elegant study that attempts to differentiate the effect of apoptosis and enterocytes detachment as a result of in vivo activated T cells.
-
(2004)
Cell Tissue Res
, vol.315
, pp. 71-84
-
-
Yaguchi, K.1
Kayaba, S.2
Soga, H.3
-
12
-
-
0025788015
-
The anti-CD3-induced syndrome: A consequence of massive in vivo cell activation
-
Chatenoud L, Ferran C, Bach JF: The anti-CD3-induced syndrome: a consequence of massive in vivo cell activation. Curr Top Microbiol Immunol 1991, 174:121-134.
-
(1991)
Curr Top Microbiol Immunol
, vol.174
, pp. 121-134
-
-
Chatenoud, L.1
Ferran, C.2
Bach, J.F.3
-
13
-
-
0036073328
-
Defining the roles of perforin, Fas/FasL, and tumour necrosis factor alpha in T cell induced mucosal damage in the mouse intestine
-
Merger M, Viney JL, Borojevic R, et al.: Defining the roles of perforin, Fas/FasL, and tumour necrosis factor alpha in T cell induced mucosal damage in the mouse intestine. Gut 2002, 51:155-163.
-
(2002)
Gut
, vol.51
, pp. 155-163
-
-
Merger, M.1
Viney, J.L.2
Borojevic, R.3
-
14
-
-
0032922117
-
Characterization of enteric functional changes evoked by in vivo anti-CD3 T cell activation
-
Radojevic N, McKay DM, Merger M, et al.: Characterization of enteric functional changes evoked by in vivo anti-CD3 T cell activation. Am J Physiol 1999, 276:R715-R723.
-
(1999)
Am J Physiol
, vol.276
-
-
Radojevic, N.1
McKay, D.M.2
Merger, M.3
-
15
-
-
0025976165
-
Triggered human mucosal T cells release tumour necrosis factor-alpha and interferon-gamma which kill human colonic epithelial cells
-
Deem RL, Shanahan F, Targan SR: Triggered human mucosal T cells release tumour necrosis factor-alpha and interferon-gamma which kill human colonic epithelial cells. Clin Exp Immunol 1991, 83:79-84.
-
(1991)
Clin Exp Immunol
, vol.83
, pp. 79-84
-
-
Deem, R.L.1
Shanahan, F.2
Targan, S.R.3
-
16
-
-
0030012072
-
T cell-monocyte interactions regulate epithelial physiology in a co-culture model of inflammation
-
McKay DM, Croitoru K, Perdue MH: T cell-monocyte interactions regulate epithelial physiology in a co-culture model of inflammation. Am J Physiol 1996, 270:C418-C428.
-
(1996)
Am J Physiol
, vol.270
-
-
McKay, D.M.1
Croitoru, K.2
Perdue, M.H.3
-
17
-
-
0027529085
-
Analysis of enteropathy induced by tumour necrosis factor alpha
-
Garside P, Bunce C, Tomlinson RC, et al.: Analysis of enteropathy induced by tumour necrosis factor alpha. Cytokine 1993, 5:24-30.
-
(1993)
Cytokine
, vol.5
, pp. 24-30
-
-
Garside, P.1
Bunce, C.2
Tomlinson, R.C.3
-
18
-
-
0347993062
-
Combining Fas mutation with interleukin-2 deficiency prevents Colitis and Lupus: Implicating interleukin-2 for autoreactive T cell expansion and Fas ligand for colon epithelial cell death
-
Xiao S, Sung SS, Fu SM, Ju ST: Combining Fas mutation with interleukin-2 deficiency prevents Colitis and Lupus: implicating interleukin-2 for autoreactive T cell expansion and Fas ligand for colon epithelial cell death. J Biol Chem 2003, 278:52730-52738, An interesting and in-depth analysis of the differential role of Fas and IL-2 in the induction of spontaneous colitis, showing that Fas is a major target for the FasL-mediated colonic damage.
-
(2003)
J Biol Chem
, vol.278
, pp. 52730-52738
-
-
Xiao, S.1
Sung, S.S.2
Fu, S.M.3
Ju, S.T.4
-
19
-
-
0141701932
-
Ameliorating effect of anti-Fas ligand mAb on wasting disease in murine model of chronic colitis
-
Dan N, Kanai T, Totsuka T, et al.: Ameliorating effect of anti-Fas ligand mAb on wasting disease in murine model of chronic colitis. Am J Physiol Gastrointest Liver Physiol 2003, 285:G754-G760. Direct evidence for the role of Fas in the induction of "wasting disease" that accompanies the colitis induced by CD45RBhi T cells.
-
(2003)
Am J Physiol Gastrointest Liver Physiol
, vol.285
-
-
Dan, N.1
Kanai, T.2
Totsuka, T.3
-
20
-
-
0030954732
-
A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease
-
Crohn's Disease cA2 Study Group
-
Targan SR, Hanauer SB, Van Deventer SJ, et al.: A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group. N Engl J Med 1997, 337:1029-1035.
-
(1997)
N Engl J Med
, vol.337
, pp. 1029-1035
-
-
Targan, S.R.1
Hanauer, S.B.2
Van Deventer, S.J.3
-
21
-
-
0022450629
-
Gut injury in mouse graft-versus-host reaction. Study of its occurrence and mechanisms
-
Guy-Grand D, Vassalli P: Gut injury in mouse graft-versus-host reaction. Study of its occurrence and mechanisms. J Clin Invest 1986, 77:1584-1595.
-
(1986)
J Clin Invest
, vol.77
, pp. 1584-1595
-
-
Guy-Grand, D.1
Vassalli, P.2
-
22
-
-
0345490989
-
Colonic bacterial superantigens evoke an inflammatory response and exaggerate disease in mice recovering from colitis
-
Lu J, Wang A, Ansari S, et al.: Colonic bacterial superantigens evoke an inflammatory response and exaggerate disease in mice recovering from colitis. Gastroenterology 2003, 125:1785-1795. This study demonstrates that DSS colitis allows for alterations in the mucosal barrier allowing for SEB administered rectally to stimulate local T cells and exacerbate the colitis.
-
(2003)
Gastroenterology
, vol.125
, pp. 1785-1795
-
-
Lu, J.1
Wang, A.2
Ansari, S.3
-
23
-
-
0037195101
-
Protection of the intestinal mucosa by intraepithelial gamma delta T cells
-
Chen Y, Chou K, Fuchs E, et al.: Protection of the intestinal mucosa by intraepithelial gamma delta T cells. Proc Natl Acad Sci USA 2002, 99:14338-14343.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 14338-14343
-
-
Chen, Y.1
Chou, K.2
Fuchs, E.3
-
26
-
-
0037033434
-
T helper 1 and T helper 2 cells are pathogenic in an antigen-specific model of colitis
-
Iqbal N, Oliver JR, Wagner FH, et al.: T helper 1 and T helper 2 cells are pathogenic in an antigen-specific model of colitis. J Exp Med 2002, 195:71-84.
-
(2002)
J Exp Med
, vol.195
, pp. 71-84
-
-
Iqbal, N.1
Oliver, J.R.2
Wagner, F.H.3
-
27
-
-
0037373210
-
T helper type-2 cells induce ileal villus atrophy, goblet cell metaplasia, and wasting disease in T cell-deficient mice
-
Dohi T, Fujihashi K, Koga T, et al.: T helper type-2 cells induce ileal villus atrophy, goblet cell metaplasia, and wasting disease in T cell-deficient mice. Gastroenterology 2003, 124:672-682. Further work that describes the nature of the mucosal damage due to Th2 cytokine-producing T cells.
-
(2003)
Gastroenterology
, vol.124
, pp. 672-682
-
-
Dohi, T.1
Fujihashi, K.2
Koga, T.3
-
28
-
-
2142643604
-
Control of immune pathology by regulatory T cells
-
Powrie F, Read S, Mottet C, et al.: Control of immune pathology by regulatory T cells. Novartis Found Symp 2003, 252:92-98(discussion 98-105, 106-114).
-
(2003)
Novartis Found Symp
, vol.252
, pp. 92-98
-
-
Powrie, F.1
Read, S.2
Mottet, C.3
-
29
-
-
0035180065
-
Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: Their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance
-
Sakaguchi S, Sakaguchi N, Shimizu J, et al.: Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol Rev 2001, 182:18-32.
-
(2001)
Immunol Rev
, vol.182
, pp. 18-32
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Shimizu, J.3
-
30
-
-
0037013968
-
A unique subset of self-specific intraintestinal T cells maintains gut integrity
-
Poussier P, Ning T, Banerjee D, Julius M: A unique subset of self-specific intraintestinal T cells maintains gut integrity. J Exp Med 2002, 195:1491-1497.
-
(2002)
J Exp Med
, vol.195
, pp. 1491-1497
-
-
Poussier, P.1
Ning, T.2
Banerjee, D.3
Julius, M.4
-
31
-
-
0347359051
-
Regulation of chronic colitis in athymic nu/nu (nude) mice
-
Laroux FS, Morris HH, Houghton J, et al.: Regulation of chronic colitis in athymic nu/nu (nude) mice. Int Immunol 2004, 16:77-89. An important study defining the role of IEL in the prevention of colitis due to CD45RBhi T cells using nude mice.
-
(2004)
Int Immunol
, vol.16
, pp. 77-89
-
-
Laroux, F.S.1
Morris, H.H.2
Houghton, J.3
-
32
-
-
0037965755
-
An important regulatory role for CD4+CD8 alpha alpha T cells in the intestinal epithelial layer in the prevention of inflammatory bowel disease
-
Das G, Augustine MM, Das J, et al.: An important regulatory role for CD4+CD8 alpha alpha T cells in the intestinal epithelial layer in the prevention of inflammatory bowel disease. Proc Natl Acad Sci USA 2003, 100:5324-5329. Evidence that CD8αα IEL can prevent colitis due to CD45RBhi T cells.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 5324-5329
-
-
Das, G.1
Augustine, M.M.2
Das, J.3
-
33
-
-
0037383809
-
Antigen-specific, CD4(+)CD25(+) regulatory T cell clones induced in Peyer's patches
-
Tsuji NM, Mizumachi K, Kurisaki J: Antigen-specific, CD4(+)CD25(+) regulatory T cell clones induced in Peyer's patches. Int Immunol 2003, 15:525-534.
-
(2003)
Int Immunol
, vol.15
, pp. 525-534
-
-
Tsuji, N.M.1
Mizumachi, K.2
Kurisaki, J.3
-
34
-
-
3843150674
-
Intestinal intraepithelial lymphocytes prevent pathogen-driven inflammation and regulate the Smad/T-bet pathway of lamina propria CD4+ T cells
-
Mennechet FJ, Kasper LH, Rachinel N, et al.: Intestinal intraepithelial lymphocytes prevent pathogen-driven inflammation and regulate the Smad/T-bet pathway of lamina propria CD4+ T cells. Eur J Immunol 2004, 34:1059-1067.
-
(2004)
Eur J Immunol
, vol.34
, pp. 1059-1067
-
-
Mennechet, F.J.1
Kasper, L.H.2
Rachinel, N.3
-
35
-
-
0031954626
-
Changes in murine jejunal morphology evoked by the bacterial superantigen Staphylococcus aureus enterotoxin B are mediated by CD4+ T cells
-
Benjamin MA, Lu J, Donnelly G, et al.: Changes in murine jejunal morphology evoked by the bacterial superantigen Staphylococcus aureus enterotoxin B are mediated by CD4+ T cells. Infect Immun 1998, 66:2193-2199.
-
(1998)
Infect Immun
, vol.66
, pp. 2193-2199
-
-
Benjamin, M.A.1
Lu, J.2
Donnelly, G.3
-
36
-
-
0032536827
-
CD4+ T cells reactive to enteric bacterial antigens in spontaneously colitic C3H/HeJBir mice: Increased T helper cell type 1 response and ability to transfer disease
-
Cong Y, Brandwein SL, McCabe RP, et al.: CD4+ T cells reactive to enteric bacterial antigens in spontaneously colitic C3H/HeJBir mice: increased T helper cell type 1 response and ability to transfer disease. J Exp Med 1998, 187:855-864.
-
(1998)
J Exp Med
, vol.187
, pp. 855-864
-
-
Cong, Y.1
Brandwein, S.L.2
McCabe, R.P.3
-
37
-
-
0037234723
-
CD4+ T regulatory cells from the colonic lamina propria of normal mice inhibit proliferation of enterobacteria-reactive, disease-inducing Th1-cells from seid mice with colitis
-
Gad M, Brimnes J, Claesson MH: CD4+ T regulatory cells from the colonic lamina propria of normal mice inhibit proliferation of enterobacteria-reactive, disease-inducing Th1-cells from seid mice with colitis. Clin Exp Immunol 2003, 131:34-40. This study shows that the colonic lamina propria T cell contain T regulatory cells that inhibit bacterial reactive Th1 T cells.
-
(2003)
Clin Exp Immunol
, vol.131
, pp. 34-40
-
-
Gad, M.1
Brimnes, J.2
Claesson, M.H.3
-
38
-
-
0033022537
-
Citrobacter rodentium infection in mice elicits a mucosal Th1 cytokine response and lesions similar to those in murine inflammatory bowel disease
-
Higgins LM, Frankel G, Douce G, et al.: Citrobacter rodentium infection in mice elicits a mucosal Th1 cytokine response and lesions similar to those in murine inflammatory bowel disease. Infect Immun 1999, 67:3031-3039.
-
(1999)
Infect Immun
, vol.67
, pp. 3031-3039
-
-
Higgins, L.M.1
Frankel, G.2
Douce, G.3
-
39
-
-
0037371361
-
Rho GTPase is activated by cytotoxic necrotizing factor 1 in peripheral blood T lymphocytes: Potential cytotoxicity for intestinal epithelial cells
-
Brest P, Mograbi B, Hofman V, et al.: Rho GTPase is activated by cytotoxic necrotizing factor 1 in peripheral blood T lymphocytes: potential cytotoxicity for intestinal epithelial cells. Infect Immun 2003, 71:1161-1169. This study defines the mechanism by which a bacterial product can stimulate T cells to induce epithelial cell damage.
-
(2003)
Infect Immun
, vol.71
, pp. 1161-1169
-
-
Brest, P.1
Mograbi, B.2
Hofman, V.3
-
40
-
-
2542523180
-
Role of CD8+ and CD4+ T Lymphocytes in Jejunal Mucosal Injury during Murine Giardiasis
-
Scott KG, Yu LC, Buret AG: Role of CD8+ and CD4+ T Lymphocytes in Jejunal Mucosal Injury during Murine Giardiasis. Infect Immun 2004, 72:3536-3542. This study defines the role of T cells in Giardia-induced mucosal injury.
-
(2004)
Infect Immun
, vol.72
, pp. 3536-3542
-
-
Scott, K.G.1
Yu, L.C.2
Buret, A.G.3
-
41
-
-
0042324649
-
Interleukin 15: A key to disrupted intraepithelial lymphocyte homeostasis and lymphomagenesis in celiac disease
-
Mention JJ, Ben Ahmed M, Begue B, et al.: Interleukin 15: a key to disrupted intraepithelial lymphocyte homeostasis and lymphomagenesis in celiac disease. Gastroenterology 2003, 125:730-745. This study shows that the epithelial derived cytokine IL-15 is critical to the pathogenesis of Celiac disease and can activate T cells to damage the intestinal epithelial cell.
-
(2003)
Gastroenterology
, vol.125
, pp. 730-745
-
-
Mention, J.J.1
Ben Ahmed, M.2
Begue, B.3
-
42
-
-
0036103112
-
Interleukin 18 is a primary mediator of the inflammation associated with dextran sulphate sodium induced colitis: Blocking interleukin 18 attenuates intestinal damage
-
Sivakumar PV, Westrich GM, Kanaly S, et al.: Interleukin 18 is a primary mediator of the inflammation associated with dextran sulphate sodium induced colitis: blocking interleukin 18 attenuates intestinal damage. Gut 2002, 50:812-820.
-
(2002)
Gut
, vol.50
, pp. 812-820
-
-
Sivakumar, P.V.1
Westrich, G.M.2
Kanaly, S.3
-
43
-
-
0036896960
-
T cell activation causes diarrhea by increasing intestinal permeability and inhibiting epithelial Na+/K+-ATPase
-
Musch MW, Clarke LL, Mamah D, et al.: T cell activation causes diarrhea by increasing intestinal permeability and inhibiting epithelial Na+/K+-ATPase. J Clin Invest 2002, 110:1739-1747.
-
(2002)
J Clin Invest
, vol.110
, pp. 1739-1747
-
-
Musch, M.W.1
Clarke, L.L.2
Mamah, D.3
-
44
-
-
1642347836
-
Intestinal intraepithelial lymphocyte gammadelta-T cell-derived keratinocyte growth factor modulates epithelial growth in the mouse
-
Yang H, Antony PA, Wildhaber BE, Teitelbaum DH: Intestinal intraepithelial lymphocyte gammadelta-T cell-derived keratinocyte growth factor modulates epithelial growth in the mouse. J Immunol 2004, 172:4151-4158. This study shows that IEL can protect against colitis via production of keratinocyte growth factor.
-
(2004)
J Immunol
, vol.172
, pp. 4151-4158
-
-
Yang, H.1
Antony, P.A.2
Wildhaber, B.E.3
Teitelbaum, D.H.4
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