TNF-induced enterocyte apoptosis and detachment in mice: Induction of caspases and prevention by a caspase inhibitor, ZVAD-fmk

Laboratory Investigation

Volumn 79, Issue 4, 1999, Pages 495-500

  Piguet, Pierre Francois ^a   Vesin, Christian ^b   Donati, Yves ^b   Barazzone, Constance ^b  

^a UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CASPASE INHIBITOR; CATHEPSIN D; TUMOR NECROSIS FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROLIFERATION; ENTEROPATHY; ENZYME ACTIVITY; ENZYME INDUCTION; INTESTINE CELL; INTESTINE VILLUS ATROPHY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AMINO ACID CHLOROMETHYL KETONES; ANIMALS; ANTIGENS, CD; APOPTOSIS; CELL ADHESION; CYSTEINE PROTEINASE INHIBITORS; DNA FRAGMENTATION; INTESTINAL MUCOSA; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MICE, KNOCKOUT; RECEPTORS, TUMOR NECROSIS FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; RECOMBINANT PROTEINS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0032958653     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Adam RD (1991). The biology of Giardia spp. Microbiol Rev 55:706-732.
2. Aoshiba K, Rennard SI, and Spurzen JR (1997). Cell-matrix and cell-cell interactions modulate apoptosis of bronchial epithelial cells. Am J Physiol 272:L28-L37.
3. Beutler B and van Huffel C (1994). Unraveling function in the TNF ligand and receptor families. Science 264:667-668.
4. Breese EJ, Michie CA, Nicholls SW, Murch SH, Williams CB, Dominzio P, Walker-Smith JA, and MacDonald TT (1994). Tumor necrosis factor alpha producing cells in the intestinal mucosa of children with inflammatory bowel disease. Gastroenterology 106:1455-1466.
5. Cohen GM (1997). Caspases: The executioners of apoptosis. Biochem J 326:1-16.
6. Dobkowski WB and Murkin JM (1998). A risk-benefit assessment of aprotinin in cardiac surgical procedures. Drug Saf 18:21-41.
7. Frisch SM and Francis H (1994). Disruption of epithelial cell-matrix interactions induces apoptosis. J Cell Biol 124: 619-626.
8. Garside P, Bunce C, Tomlinson C, Nichols BL, and Mowat AM (1993). Analysis of enteropathy induced by tumor necrosis factor alpha. Cytokine 5:24-30.
9. Gavrieli Y, Sherman Y, and Ben-Sasson SA (1992). Identification of programmed cell death in situ via specific labelling of nuclear DNA fragmentation. J Cell Biol 119:493-501.
10. Gearing AJH, Beckett P, Christodoulou M, Churchill M, Clements JM, Crimmin M, Davidson AH, Drummond AH, Galloway WA, Gilbert R, et al (1995). Matrix metalloproteinases and processing of pro-TNF-alpha. J Leukoc Biol 57: 774-777.
11. Gordon JI and Hermiston ML (1994). Differentiation and self-renewal in the mouse gastrointestinal epithelium. Curr Opin Cell Biol 6:795-803.
12. Grossmann J, Maxson JM, Whitacre CM, Orosz DE, Berger NA, Fiocchi C, and Levine AD (1998). New isolation technique to study apoptosis in human intestinal epithelial cells. Am J Pathol 153:53-62.
13. Kerr JFR, Bishop CJ, Searle J, Harmon BV, and Bishop CW (1987). Apoptosis. In: Potten CS, editor: Perspective in mammalian cell death. Oxford: Oxford Science Publications, 93-128.
14. Mann HB and Whitney DR (1947). On a test of whether one or two random variables is stochastically larger than the other. Ann Math Statist 18:50-60.
15. Mowat AM and Ferguson A (1981). Hypersensitivity reactions in the small intestine. Transplantation 32:238-243.
16. Nagata S (1997). Apoptosis by death factor. Cell 88:355-365.
17. Pena AS, Garrote JA, and Crusius JB (1998). Advances in the immunogenetics of coeliac disease. Clues for understanding the pathogenesis and disease heterogeneity. Scand J Gastroenterol Suppl 225:56-58.
18. Pender SLF, Tickle SP, Docherty AJP, Howie D, Wathen NC, and MacDonald TT (1997). A major role for matrix metalloproteinases in T cell injury in the gut. J Immunol 158:1582-1590.
19. Pfeffer K, Matsuyama T, Kundig TM, Wakeham A, Kishihara K, Shahinian A, Wiegman K, Ohashi PS, Kronke M, and Mak TW (1993). Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection. Cell 73:457-467.
20. Piguet PF, Grau GE, Allet B, and Vassalli P (1987). Tumor necrosis factor is an effector of skin and gut lesions of the acute phase of graft-versus-host disease. J Exp Med 166: 1280-1289.
21. Piguet PF, Vesin C, Guo J, Donati Y, and Barazzone C (1998). TNF-induced enterocyte apoptosis in mice is mediated by the TNFR1 and does not require p53. Eur J Immunol 28: 3499-3506.
22. Rodriguez I, Matsuura K, Ody C, Nagata S, and Vassalli P (1996). Systemic injection of a tripeptide inhibits the intracellular activation of CCP32-like proteases in vivo and fully protects mice against Fas-mediated fulminant liver destruction and death. J Exp Med 184:2067-2072.
23. Rothe J, Lesslauer W, Lotscher H, Lang Y, Koebel P, Kontgen F, Althage A, Zinkernagel R, Steinmetz M, and Bluethman H (1993). Mice lacking the tumor necrosis receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes. Nature 364:798-802.
24. Ruoslahti E (1997). Stretching is good for a cell. Science 276:1345-1346.
25. Thompson CB (1995). Apoptosis in the pathogenesis and treatment of disease. Science 267:1456-1462.
26. Wilhelm S, Wagner H, and Hacker G (1998). Activation of caspase-3-like enzymes in non-apoptotic T cells. Eur J Immunol 28:891-900.
27. Woo M, Hakem R, Soengas MS, Duncan GS, Shahinian A, Kagi D, Hakem A, McCurrach M, Khoo W, Kaufman SA, Senaldi G, Howard T, Lowe SW, and Mak TW (1998). Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes. Genes Dev 12:806-819.