PUMA-mediated intestinal epithelial apoptosis contributes to ulcerative colitis in humans and mice

Journal of Clinical Investigation

Volumn 121, Issue 5, 2011, Pages 1722-1732

  Qiu, Wei ^a,b   Wu, Bin ^a,b   Wang, Xinwei ^a,b   Buchanan, Monica E ^a,b   Regueiro, Miguel D ^b   Hartman, Douglas J ^b   Schoen, Robert E ^a,b   Yu, Jian ^a,b   Zhang, Lin ^a,b  

^a UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEXTRAN SULFATE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INFLIXIMAB; PROTEIN BID; PROTEIN P53; PUMA PROTEIN; TRINITROBENZENESULFONIC ACID;

ADOLESCENT; ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CHILD; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE SEVERITY; DRUG EFFECT; FEMALE; HUMAN; HUMAN TISSUE; INTESTINE EPITHELIUM; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; ULCERATIVE COLITIS;

ADOLESCENT; ADULT; AGED; ANIMALS; ANTIBODIES, MONOCLONAL; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CHILD; COLITIS, ULCERATIVE; DEXTRAN SULFATE; EPITHELIAL CELLS; FEMALE; HUMANS; INTESTINES; MALE; MICE; MICE, KNOCKOUT; MIDDLE AGED; NF-KAPPA B; PROTO-ONCOGENE PROTEINS; TRINITROBENZENESULFONIC ACID; TUMOR NECROSIS FACTOR-ALPHA; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 79955501236     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI42917     Document Type: Article

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