Fine-Tuning Next-Generation Genome Editing Tools

Trends in Biotechnology

Volumn 34, Issue 7, 2016, Pages 562-574

  Kanchiswamy, Chidananda Nagamangala ^a   Maffei, Massimo ^b   Malnoy, Mickael ^a   Velasco, Riccardo ^a   Kim, Jin Soo ^c,d  

^a RESEARCH AND INNOVATION CENTRE   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

^c Institute for Basic Science   (South Korea)

^d Seoul National University   (South Korea)

Author keywords

CRISPR Cas9; Genome editing; Off target; On target; TALENs; Target specificity; ZFNs

Indexed keywords

AGRICULTURE; BIOLOGY; CLONE CELLS; PLANTS (BOTANY);

CRISPR/CAS9; GENOME-WIDE PROFILING; HIGH-THROUGHPUT ANALYSIS; METHOD OF DELIVERY; MUTATION EFFECTS; NUCLEASE CLEAVAGE; TALENS; ZFNS;

GENES;

CHEMOKINE RECEPTOR CCR5; GENOMIC DNA; GUIDE RNA; NUCLEASE; RNA GUIDED ENGINEERED NUCLEASE; STREPTAVIDIN; TRANSCRIPTION ACTIVATOR LIKE EFFECTOR NUCLEASE; UNCLASSIFIED DRUG; ZINC FINGER NUCLEASE;

AGRICULTURE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; COMPUTER MODEL; COMPUTER PROGRAM; CRISPR CAS SYSTEM; DNA REPAIR; DNA SEQUENCE; DOUBLE STRANDED DNA BREAK; GENE SEQUENCE; GENETIC ENGINEERING; GENOME; HOMOLOGOUS RECOMBINATION; HUMAN; MUTATION; NEXT GENERATION SEQUENCING; PHENOTYPE; PRIORITY JOURNAL; REVIEW; BIOTECHNOLOGY; COMPARATIVE STUDY; GENE EDITING; GENE THERAPY; PROCEDURES;

AGRICULTURE; BIOTECHNOLOGY; GENE EDITING; GENETIC THERAPY;

EID: 84973862383     PISSN: 01677799     EISSN: 18793096     Source Type: Journal    
DOI: 10.1016/j.tibtech.2016.03.007     Document Type: Review

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