Measuring and reducing off-target activities of programmable nucleases including CRISPR-Cas9

Molecules and Cells

Volumn 38, Issue 6, 2015, Pages 475-481

  Koo, Taeyoung ^a,c   Lee, Jungjoon ^b   Kim, Jin Soo ^a,b,c  

^a Institute for Basic Science   (South Korea)

^b Seoul National University   (South Korea)

^c University of Science and Technology (UST)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CRISPR ASSOCIATED PROTEIN; CRISPR ASSOCIATED PROTEIN 9; NUCLEASE; UNCLASSIFIED DRUG; ENDONUCLEASE;

CRISPR CAS SYSTEM; ENZYME ACTIVITY; GENOME; HUMAN; MUTATION; NONHUMAN; OFF TARGET MUTATION; ON TARGET MUTATION; PROTEIN CLEAVAGE; REVIEW; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; GENETIC ENGINEERING; GENETICS;

CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; CRISPR-CAS SYSTEMS; ENDONUCLEASES; GENETIC ENGINEERING; HUMANS;

EID: 84938739634     PISSN: 10168478     EISSN: 02191032     Source Type: Journal    
DOI: 10.14348/molcells.2015.0103     Document Type: Review

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