Antimicrobial activity of plant-food by-products: A review focusing on the tropics

Livestock Science

Volumn 189, Issue , 2016, Pages 32-49

  Guil Guerrero, J L ^a,b   Ramos, L ^a   Moreno, C ^a   Zuniga Paredes J C ^a   Carlosama Yepez, M ^a   Ruales, P ^a  

^a AGROCALIDAD   (Ecuador)

^b UNIVERSITY OF ALMERÍA   (Spain)

Author keywords

Antibiotic resistance; Antimicrobial activity; Essential oils; Minimum inhibitory concentration; Phenolics; Tropical plant food by products

Indexed keywords

EID: 84967019961     PISSN: 18711413     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.livsci.2016.04.021     Document Type: Review

References (123)

1. Abdalla A.E., Darwish S.M., Ayad E.H., El-Hamahmy R.M. Egyptian mango by-product 2: antioxidant and antimicrobial activities of extract and oil from mango seed kernel. Food Chem. 2007, 103:1141-1152.
2. Akinyele T.A., Okoh O.O., Akinpelu D.A., Okoh A.I. In-vitro antibacterial properties of crude aqueous and n-hexane extracts of the husk of Cocos nucifera. Molecules 2011, 16:2135-2145.
3. Akiyama H., Fujii K., Yamasaki O., Oono T., Iwatsuki K. Antibacterial action of several tannins against Staphylococcus aureus. J. Antimicrob. Chemother. 2001, 48:487-491.
4. Alanis A.J. Resistance to antibiotics: are we in the post-antibiotic era?. Arch. Med. Res. 2005, 36:697-705.
5. Almajano M.P., Carbo R., Delgado M.E., Gordon M.H. Effect of pH on the antimicrobial activity and oxidative stability of oil-in-water emulsions containing caffeic acid. J. Food Sci. 2007, 72:258-263.
6. Alvesalo J., Vuorela H., Tammela P., Leinonen M., Saikku P., Vuorela P. Inhibitory effect of dietary phenolic compounds on Chlamydia pneumoniae in cell cultures. Biochem. Pharmacol. 2006, 71:735-741.
7. Andrews J.M. Determination of minimum inhibitory concentrations. J. Antimicrob. Chemother. 2001, 48:5-16.
8. Avato P., Bucci R., Tava A., Vitali C., Rosato A., Bialy Z., Jurzysta M. Antimicrobial activity of saponins from Medicago sp.: structure-activity relationship. Phytother. Res. 2006, 20:454-457.
9. Assayed M.E., Abd El-Aty A.M. Cruciferous plants: phytochemical toxicity versus cancer chemoprotection. Mini Rev. Med. Chem. 2009, 9:1470-1478.
10. Ayala-Zavala J.F., Vega-Vega V., Rosas-Domínguez C., Palafox-Carlos H., Villa-Rodríguez J.A., Siddiqui M.W., Dávila-Aviña J.E., González-Aguilar G.A. Agro-industrial potential of exotic fruit byproducts as a source of food additives. Food Res. Int. 2011, 44:1866-1874.
11. Al-Delaimy K.S., Ali S.H. Antibacterial action of vegetable extracts on the growth of pathogenic bacteria. J. Sci. Food Agric. 1970, 21:110-112.
12. Bahraminejad S., Asenstorfer R.E., Riley I.T., Schultz C.J. Analysis of the antimicrobial activity of flavonoids and saponins isolated from the shoots of oats (Avena sativa L.). J. Phytopath. 2008, 156:1-7.
13. Batovska D., Parushev S., Stamboliyska B., Tsvetkova I., Ninova M., Najdenski H. Examination of growth inhibitory properties of synthetic chalcones for which antibacterial activity was predicted. Eur. J. Med. Chem. 2009, 44:2211-2218.
14. Bocquier F., González-García E. Sustainability of ruminant agriculture in the new context: feeding strategies and features of animal adaptability into the necessary holistic approach. Animal 2010, 4:1258-1273.
15. Bubonja-Sonje M., Giacometti J., Abram M. Antioxidant and antilisterial activity of olive oil, cocoa and rosemary extract polyphenols. Food Chem. 2011, 127:1821-1827.
16. Burt S. Essential oils: their antibacterial properties and potential application in foods: a review. Int. J. Food Microbiol. 2004, 94:223-253.
17. Cowan M.M. Plant products as antimicrobial agents. Clin. Microbiol. Rev. 1999, 12:564-582.
18. Cuéllar O., Quím T., Guerrero G. Antibacterial activity of the cacao bean husk, Theobroma cacao L. Rev. MVZ Córdoba 2012, 17:3176-3183.
19. Cueva C., Moreno-Arribas M.V., Martín-Álvarez P.J., Bills G., Vicente M.F., Basilio A., López Rivas C., Requena T., Rodríguez J.M., Bartolomé B. Antimicrobial activity of phenolic acids against commensal, probiotic and pathogenic bacteria. Res. Microbiol. 2010, 161:372-382.
20. Cushnie T.T., Lamb A.J. Recent advances in understanding the antibacterial properties of flavonoids. Int. J. Antimicrob. Agents 2011, 38:99-107.
21. Cushnie T.P.T., Hamilton V.E.S., Chapman D.G., Taylor P.W., Lamb A.J. Aggregation of Staphylococcus aureus following treatment with the antibacterial flavonol galangin. J. Appl. Microbiol. 2007, 103:1562-1567.
22. Daglia M. Polyphenols as antimicrobial agents. Curr. Opin. Biotech. 2012, 23:174-181.
23. Dai J., Mumper R.J. Plant phenolics: extraction, analysis and their antioxidant and anticancer properties. Molecules 2010, 15:7313-7352.
24. Díaz G.J. Toxicosis by plant alkaloids in humans and animals in Colombia. Toxins 2015, 7:5408-5416.
25. Dixon R.A., Xie D.Y., Sharma S.B. Proanthocyanidins - a final frontier in flavonoid research?. New Phytol. 2005, 165:9-28.
26. Doughari J.H. Antimicrobial activity of Tamarindus indica Linn. Trop. J. Pharm. Res. 2007, 5:597-603.
27. e Silva D.O., Martins G.R., da Silva A.J.R., Alviano D.S., Nascimento R.P., Kaplan M.A.C., Alviano C.S. Chemical and antimicrobial analysis of husk fiber aqueous extract from Cocos nucifera L. Afr. J. Biotech. 2013, 12:2478-2483.
28. El-Hawary S.S., Rabeh M.A. Mangifera indica peels: a common waste product with impressive immunostimulant, anticancer and antimicrobial potency. J. Nat. Sci. Res. 2014, 4:102-115.
29. Engels C., KNOdler M.A.T.T.H.I.A.S., Zhao Y.Y., Carle R., Gänzle M.G., Schieber A. Antimicrobial activity of gallotannins isolated from mango (Mangifera indica L.) kernels. J. Agric. Food Chem. 2009, 57:7712-7718.
30. Engels C., Schieber A., Gänzle M.G. Studies on the inhibitory spectrum and mode of antimicrobial action of gallotannins from mango kernels (Mangifera indica L.). Appl. Environ. Microbiol. 2011, 77:2215-2223.
31. Erdemoglu N., Ozkan S., Tosun F. Alkaloid profile and antimicrobial activity of Lupinus angustifolius L. alkaloid extract. Phytochem. Rev. 2007, 6:197-201.
32. Esquenazi D., Wigg M.D., Miranda M.M., Rodrigues H.M., Tostes J.B., Rozental S., da Silva A.J.R., Alviano C.S. Antimicrobial and antiviral activities of polyphenolics from Cocos nucifera Linn. (Palmae) husk fiber extract. Res. Microbiol. 2002, 153:647-652.
33. Fahey J.W., Zalcmann A.T., Talalay P. The chemical diversity and distribution of glucosinolates and isothiocyanates among plants. Phytochem 2001, 56:5-51.
34. Farrar W.E. Antibiotic resistance in developing countries. J. Infect. Dis. 1985, 1103-1106.
35. Francis G., Kerem Z., Makkar H.P., Becker K. The biological action of saponins in animal systems: a review. Br. J. Nutr. 2002, 88:587-605.
36. Friedman M., Henika P.R., Levin C.E., Mandrell R.E., Kozukue N. Antimicrobial activities of tea catechins and theaflavins and tea extracts against Bacillus cereus. J. Food Prot. 2006, 69:354-361.
37. Ghasemzadeh A., Ghasemzadeh N. Flavonoids and phenolic acids: role and biochemical activity in plants and human. J. Med. Plants Res. 2011, 5:6697-6703.
38. Giannenas I., Florou-Paneri P., Papazahariadou M., Christaki E., Botsoglou N.A., et al. Effect of dietary supplementation with oregano essential oil on performance of broilers after experimental infection with Eimeria tenella. Arch. Tierernahr. 2003, 57:99-106.
39. Greathead H. Plants and plant extracts for improving animal productivity. Proc. Nutr. Soc. 2003, 62:279-290.
40. Grujić S.M., Radojević I.D., Vasić S.M., Čomić L.R., Topuzović M.D. Antimicrobial and antibiofilm activities of secondary metabolites from Vinca minor L. Appl. Biochem. Microbiol. 2015, 51:572-578.
41. Hagerman A.E., Riedl K.M., Jones G.A., Sovik K.N., Ritchard N.T., Hartzfeld P.W., Riechel T.L. High molecular weight plant polyphenolics (tannins) as biological antioxidants. J. Agric. Food Chem. 1998, 46:1887-1892.
42. Hamilton S.E. The Impact of Shrimp Farming on Mangrove Ecosystems and Local Livelihoods Along the Pacific coast of Ecuador (Doctoral dissertation) 2011, The University of Southern Mississippi, USA.
43. Hart C.A., Kariuki S. Antimicrobial resistance in developing countries. Br. Med. J. 1998, 317:647.
44. Hassan S.M., Byrd J.A., Cartwright A.L., Bailey C.A. Hemolytic and antimicrobial activities differ among saponin-rich extracts from guar, quillaja, yucca, and soybean. Appl. Biochem. Biotech. 2010, 162:1008-1017.
45. Havsteen B. Flavonoids, a class of natural products of high pharmacological potency. Biochem. Pharmacol. 1983, 32:1141-1148.
46. Heinonen M. Antioxidant activity and antimicrobial effect of berry phenolics - a Finnish perspective. Mol. Nutr. Food Res. 2007, 51:684-691.
47. Helander I.M., Alakomi H.L., Latva-Kala K., Mattila-Sandholm T., Pol I., Smid E.J., Gorris L.G.M., von Wright A. Characterization of the action of selected essential oil components on Gram-negative bacteria. J. Agric. Food Chem. 1998, 46:3590-3595.
48. Hellberg R.S., Chu E. Effects of climate change on the persistence and dispersal of foodborne bacterial pathogens in the outdoor environment: a review. Crit. Rev. Microbiol. 2015, 1-25.
49. Heuer O.E., Kruse H., Grave K., Collignon P., Karunasagar I., Angulo F.J. Human health consequences of use of antimicrobial agents in aquaculture. Clin. Infect. Dis. 2009, 49(8):1248-1253.
50. Hirasawa M., Takada K. Multiple effects of green tea catechin on the antifungal activity of antimycotics against Candida albicans. J. Antimicrob. Chemother. 2004, 53:225-229.
51. Holmström K., Gräslund S., Wahlström A., Poungshompoo S., Bengtsson B.E., Kautsky N. Antibiotic use in shrimp farming and implications for environmental impacts and human health. Int. J. Food Sci. Tech. 2003, 38:255-266.
52. Iorizzi M., Lanzotti V., Ranalli G., De Marino S., Zollo F. Antimicrobial Furostanol Saponins from the Seeds of Capsicum annuum L. Var. acuminatum. J. Agric. Food Chem. 2002, 50:4310-4316.
53. Jenkins K.J., Atwal A.S. Effects of dietary saponins on fecal bile acids and neutral sterols, and availability of vitamins A and E in the chick. J. Nutr. Biochem. 1994, 5:134-137.
54. Jiménez-Arellanes A., Luna-Herrera J., Ruiz-Nicolás R., Cornejo-Garrido J., Tapia A., Yépez-Mulia L. Antiprotozoal and antimycobacterial activities of Persea americana seeds. BMC Complement. Altern. Med 2013, 13:109.
55. Kabuki T., Nakajima H., Arai M., Ueda S., Kuwabara Y., Dosako S.I. Characterization of novel antimicrobial compounds from mango (Mangifera indica L.) kernel seeds. Food Chem. 2000, 71:61-66.
56. Kannabiran K., Mohankumar T., Gunaseker V. Evaluation of antimicrobial activity of saponin isolated from Solanum xanthocarpum and Centella asiatica. Int. J. Nat. Eng. Sci. 2009, 3:22-25.
57. Karadi R.V., Shah A., Parekh P., Azmi P. Antimicrobial activities of Musa paradisiaca and Cocos nucifera. Int. J. Res. Pharm. Biomed. Sci. 2011, 2:264-267.
58. Karthy E.S., Ranjitha P. Screening of antibacterial tannin compound from mango (Mangifera indica) seed kernel extract against Methicillin resistant Staphylococcus aureus (MRSA). Elixir Pharm. C 2011, 40:5251-5255.
59. Keeler R.F. Quinolizidine alkaloids in range and grain lupin. Toxicants of Plant Origin 1989, vol. 1:134-159. CRC Press, Boca Raton, FL. P.R. Cheeke (Ed.).
60. Khammuang S., Sarnthima R. Antioxidant and antibacterial activities of selected varieties of thai mango seed extract. Pak. J. Pharm. Sci. 2011, 24:37-42.
61. Killeen G.F., Madigan C.A., Connolly C.R., Walsh G.A., Clark C., Hynes M.J., Timmins B.F., James P., Headon D.R., Power R.F. Antimicrobial saponins of Yucca schidigera and the implications of their in vitro properties for their in vivo impact. J. Agric. Food Chem. 1998, 46:3178-3186.
62. Kücükyillmaz K., Bozkurt M., Selek N., Guven E., Eren H., Ataseveret A., Bintas E., Çatli A.U., Çinar M. Effects of vaccination against coccidiosis, with and without a specific herbal essential oil blend, on performance, oocyst excretion and serum IBD titers of broilers rearedon litter. Ital. J. Anim. Sci. 2012, 11:e1.
63. Kumar R., Vaithiyanathan S. Occurrence, nutritional significance and effect on animal productivity of tannins in tree leaves. Anim. Feed Sci. Tech. 1990, 30:21-38.
64. Lambert R.J.W., Skandamis P.N., Coote P., Nychas G.-J.E. A study of the minimum inhibitory concentration and mode of action of oregano essential oil, thymol and carvacrol. J. Appl. Microbiol. 2001, 91:453-462.
65. Larrauri J.A., Rupérez P., Borroto B., Saura-Calixto F. Mango peels as a new tropical fibre: preparation and characterization. LWT-Food Sci. Technol. 1996, 29:729-733.
66. Lee K., Everts W.H., Beynen A.C. Essential oils in broiler nutrition. Int. J. Poult. Sci. 2004, 9:738-752.
67. Lee K.M., Kim W.S., Lim J., Nam S., Youn M., Nam S.W., Kim Y., Kim S.H., Park W., Park S. Antipathogenic properties of green tea polyphenol epigallocatechin gallate at concentrations below the MIC against enterohemorrhagic Escherichia coli O157:H7. J. Food Prot. 2009, 72:325-331.
68. Li G., Xu Y., Wang X., Zhang B., Shi C., Zhang W., Xia X. Tannin-rich fraction from pomegranate rind damages membrane of Listeria monocytogenes. Foodborne Pathog. Dis. 2014, 11:1-7.
69. Liang Y., Xu Q., Xie H., Zhou Y., Wei X. Chemical constituents from mango seed kernels and their antimicrobial activity. J. Trop. Subtrop. Bot. 2010, 4:020.
70. Lipp E.K., Huq A., Colwell R.R. Effects of global climate on infectious disease: the cholera model. Clin. Microbiol. Rev. 2002, 15:757-770.
71. Ma H., Liu W., Frost L., Wang L., Kong L., Dain J.A., Seeram N.P. The hydrolyzable gallotannin, penta-O-galloyl-β-d-glucopyranoside, inhibits the formation of advanced glycation endproducts by protecting protein structure. Mol. Biosyst. 2015, 11:1338-1347.
72. Mahapatra D.K., Bharti S.K., Asati V. Chalcone scaffolds as anti-infective agents: structural and molecular target perspectives. Eur. J. Med. Chem. 2015, 101:496-524.
73. Managaki S., Murata A., Takada H., Tuyen B.C., Chiem N.H. Distribution of macrolides, sulfonamides, and trimethoprim in tropical waters: ubiquitous occurrence of veterinary antibiotics in the Mekong Delta. Environ. Sci. Tech. 2007, 41:8004-8010.
74. Mandalari G., Bennett R.N., Bisignano G., Trombetta D., Saija A., Faulds C.B., Gasson M.J., Narbad A. Antimicrobial activity of flavonoids extracted from bergamot (Citrus bergamia Risso) peel, a byproduct of the essential oil industry. J. Appl. Microbiol. 2007, 103:2056-2064.
75. Merkl R., Hradkova I., Filip V., ŠMIdRkal J. Antimicrobial and antioxidant properties of phenolic acids alkyl esters. Czech J. Food Sci. 2010, 28:275-279.
76. Milewski, I., 2001. Impacts of salmon aquaculture on the coastal environment: a review. In: Tlusty, M.F., Bengston, D.A., Halvorson, H.O., Oktay, S.D., Pearce, J.B., Rheault Jr., R. B. (Eds), (Marine Aquaculture and the Environment): A Meeting for Stakeholders in the Northeast. Cape Cod Press, Falmouth, MA, pp. 166-197.
77. Morales F.J. Introduction to tropical agriculture and outlook for tropical crops in a globalized economy. Tropical Biology Conservation Management 2009, III.
78. Negesse T., Makkar H.P.S., Becker K. Nutritive value of some non-conventional feed resources of Ethiopia determined by chemical analyses and an in vitro gas method. Anim. Feed Sci. Technol. 2009, 154:204-217.
79. Negi P.S., Jayaprakasha G.K., Jagan Rao Mohan L., Sakariah K.K. Antibacterial activity of turmeric oil: a byproduct from curcumin. J. Agric. Food Chem. 1999, 47:4297-4300.
80. Nitiema L.W., Savadogo A., Simpore J., Dianou D., Traore A.S. In vitro antimicrobial activity of some phenolic compounds (coumarin and quercetin) against gastroenteritis bacterial strains. Inter. J. Microbiol. Res. 2012, 3:183-187.
81. Nsor-Atindana J., Zhong F., Mothibe K.J., Bangoura M.L., Lagnika C. Quantification of total polyphenolic content and antimicrobial activity of cocoa (Theobroma cacao L.) Bean Shells. Pak. J. Nutr. 2012, 11:574-579.
82. Okeke I.N., Lamikanra A., Edelman R. Socioeconomic and behavioral factors leading to acquired bacterial resistance to antibiotics in developing countries. Emerg. Infect. Dis. 1999, 5:18.
83. Okeke I.N., Edelman R. Dissemination of antibiotic-resistant bacteria across geographic borders. Clin. Infect. Dis. 2001, 33:364-369.
84. Okeke I.N., Laxmaninarayan R., Bhutta Z.A., Duse A.G., Jenkins P., O'Brien T.F., Pablos-Mendez A., Klugman K.P. Antimicrobial resistance in developing countries. Part I: recent trends and current status. Lancet Infect. Dis. 2005, 5:481-493.
85. Oliveira S.M.S.D., Falcão-Silva V.S., Siqueira-Junior J.P., Costa M.J.D.C., Diniz M.D.F.F.D. Modulation of drug resistance in Staphylococcus aureus by extract of mango (Mangifera indica L., Anacardiaceae) peel. Rev. Bras. Farmacogn. 2011, 21:190-193.
86. Oltjen J.W., Beckett J.L. Role of ruminant livestock in sustainable agricultural systems. J. Anim. Sci. 1996, 74:1406-1409.
87. Osman C.P., Ramlan I.H. GC-MS analyses of essential oils of three varieties of Mangifera indica. J. Teknol. 2015, 77:47-50.
88. Özçelik B., Kartal M., Orhan I. Cytotoxicity, antiviral and antimicrobial activities of alkaloids, flavonoids, and phenolic acids. Pharm. Biol. 2011, 49:396-402.
89. Padam B.S., Tin H.S., Chye F.Y., Abdullah M.I. Antibacterial and antioxidative activities of the various solvent extracts of banana (Musa paradisiaca cv. Mysore) inflorescences. J. Biol. Sci. 2012, 12:62-73.
90. Price K.R., Johnson I.T., Fenwick G.R., Malinow M.R. The chemistry and biological significance of saponins in foods and feedingstuffs. Crit. Rev. Food Sci. Nutr. 1987, 26:27-135.
91. Raymond Chia T.W., Dykes G.A. Antimicrobial activity of crude epicarp and seed extracts from mature avocado fruit (Persea americana) of three cultivars. Pharm. Biol. 2010, 48:753-756.
92. Reddy, N., Yang, Y., 2015. Coconut Husk Fibers, In: Innovative Biofibers from Renewable Resources. Springer Heidelberg, Berlin, pp. 31-34.
93. Rios M.Y., Olivo H.F. Natural and synthetic alkamides: applications in pain therapy. Stud. Nat. Prod. Chem. 2014, 79.
94. Rochfort S., Parker A.J., Dunshea F.R. Plant bioactives for ruminant health and productivity. Phytochem 2008, 69:299-322.
95. Rodríguez-Carpena J.G., Morcuende D., Andrade M.J., Kylli P., Estévez M. Avocado (Persea americana Mill.) phenolics, in vitro antioxidant and antimicrobial activities, and inhibition of lipid and protein oxidation in porcine patties. J. Agric. Food Chem. 2011, 59:5625-5635.
96. Saavedra M.J., Borges A., Dias C., Aires A., Bennett R.N., Rosa E.S., Simões M. Antimicrobial activity of phenolics and glucosinolate hydrolysis products and their synergy with streptomycin against pathogenic bacteria. Med. Chem. 2010, 6:174-183.
97. Sahu S.W.A.G.A.T.I.K.A., Das B.K., Mishra B.K. Multiple antibacterial and Phytochemical analysis of Mango Kernel extracts on Aquatic and Animal Pathogens. Int. J. Pharm. Bio. Sci. 2013, 4:809-818.
98. Sánchez-Maldonado A.F. Mode of Action, (Interaction and Recovery of Plant Secondary Metabolites for Potential Applications as Food Preservatives (Doctoral Dissertation) 2014, University Of Alberta, Canada.
99. Sarmah A.K., Meyer M.T., Boxall B A. A global perspective on the use, sales, exposure pathways, occurrence, fate and effects of veterinary antibiotics (VAs) in the environment. Chemosphere 2006, 65:725-759.
100. Séveno N.A., Kallifidas D., Smalla K., van Elsas J.D., Collard J.M., Karagouni A.D., Wellington E.M. Occurrence and reservoirs of antibiotic resistance genes in the environment. Rev. Med. Microbiol. 2002, 13:15-27.
101. Scalbert A. Antimicrobial properties of tannins. Phytochem 1991, 30:3875-3883.
102. Schieber A., Stintzing F.C., Carle R. By-products of plant food processing as a source of functional compounds-recent developments. Trends Food Sci. Tech. 2001, 12:401-413.
103. Shabtay A., Eitam H., Tadmor Y., Orlov A., Meir A., Weinberg P., Weinberg Z.G., Chen Y., Brosh A., Izhaki I., Kerem Z. Nutritive and antioxidative potential of fresh and stored pomegranate industrial byproduct as novel beef cattle feed. J. Agric. Food Chem. 2008, 56:10063-10070.
104. Si W., Gong J., Tsao R., Zhou T., Yu H., Poppe C., Johnson R., Du Z. Antimicrobial activity of essential oils and structurally related synthetic food additives towards selected pathogenic and beneficial gut bacteria. J. Appl. Microbiol. 2006, 296-305.
105. Sikkema J.J., De Bont A.M., Poolman B. Interactions of cyclic hydrocarbons with biological membranes. J. Biol. Chem. 1994, 269:8022-8028.
106. Singer R.S., Hofacre C.L. Potential impacts of antibiotic use in poultry production. Avian Dis. 2006, 50:161-172.
107. Slanina P. Solanine (glycoalkaloids) in potatoes: toxicological evaluation. Food Chem. Toxicol. 1990, 28:759-761.
108. Sotillo D.R., Hadley M., Wolf-Hall C. Potato peel extract a nonmutagenic antioxidant with potential antimicrobial activity. J. Food Sci. 1998, 63:907-910.
109. Sparg S., Light M.E., Van Staden J. Biological activities and distribution of plant saponins. J. Ethnopharmacol. 2004, 94:219-243.
110. Soong Y.Y., Barlow P.J. Antioxidant activity and phenolic content of selected fruit seeds. Food Chem. 2004, 88:411-417.
111. Suárez M., Haenni M., Canarelli S., Fisch F., Chodanowski P., Servis C., Michielin O., Freitag R., Moreillon P., Mermod N. Structure-function characterization and optimization of a plant-derived antibacterial peptide. Antimicrob. Agents Chemother. 2005, 49:3847-3857.
112. Takara K., Ushijima K., Wada K., Iwasaki H., Yamashita M. Phenolic compounds from sugarcane molasses possessing antibacterial activity against cariogenic bacteria. J. Oleo Sci. 2007, 56:611-614.
113. Tan Y.N., Ayob M.K., Yaacob W.A.W. Purification and characterisation of antibacterial peptide-containing compound derived from palm kernel cake. Food Chem. 2013, 136:279-284.
114. Taveira M., Silva L.R., Vale-Silva L.A., Pinto E., Valentão P., Ferreres F., Guedes De Pinho P., Andrade P.B. Lycopersicon esculentum seeds: an industrial byproduct as an antimicrobial agent. J. Agric. Food Chem. 2010, 58:9529-9536.
115. Tsuchiya H., Sato M., Miyazaki T., Fujiwara S., Tanigaki S., Ohyama M., Tanaka T., Iinuma M. Comparative study on the antibacterial activity of phytochemical flavanones against methicillin-resistant Staphylococcus aureus. J. Ethnopharmacol. 1996, 50:27-34.
116. Uematsu Y., Hirata K., Saito K., Kudo I. Spectrophotometric determination of saponin in Yucca extract used as food additive. J. AOAC Int. 2000, 83:1451-1454.
117. Van Parys A., Boyen F., Dewulf J., Haesebrouck F., Pasmans F. The use of tannins to control Salmonella typhimurium infections in pigs. Zoonoses Public Health 2010, 57:423-428.
118. Wei Y.X., Shuai L., Guo D.S., Li S., Wang F.L., Ai G.H. Study on antibacterial activity of capsaicin. Food Sci. 2006, 8:012.
119. Wen A., Delaquis P., Stanich K., Toivonen P. Antilisterial activity of selected phenolic acids. Food Microbiol. 2003, 20:305-311.
120. Woappi Y., Gabani P., Singh A., Singh O.V. Antibiotrophs: the complexity of antibiotic-subsisting and antibiotic-resistant microorganisms. Crit. Rev. Microbiol. 2014, 1101-1114.
121. Xie Z., Ma X., Gang D.R. Modules of co-regulated metabolites in turmeric (Curcuma longa) rhizome suggest the existence of biosynthetic modules in plant specialized metabolism. J. Exp. Bot. 2009, 60:87-97.
122. Zhao Y., Chen M., Zhao Z., Yu S. The antibiotic activity and mechanisms of sugarcane (Saccharum officinarum L.) bagasse extract against food-borne pathogens. Food Chem. 2015, 185:112-118.
123. Zhu Y.G., Johnson T.A., Su J.Q., Qiao M., Guo G.X., Stedtfeld R.D., Hashsham S.A., Tiedje J.M. Diverse and abundant antibiotic resistance genes in Chinese swine farms. Proc. Natl. Acad. Sci. USA 2013, 110:3435-3440.