-
1
-
-
79959447465
-
Structural biology of the toll-like receptor family
-
Kang JY, Lee JO. Structural biology of the toll-like receptor family. Annu Rev Biochem (2011) 80:917-41. doi: 10.1146/annurev-biochem-052909-141507
-
(2011)
Annu Rev Biochem
, vol.80
, pp. 917-941
-
-
Kang, J.Y.1
Lee, J.O.2
-
2
-
-
84890235827
-
The interleukin-1 family: back to the future
-
Garlanda C, Dinarello CA, Mantovani A. The interleukin-1 family: back to the future. Immunity (2013) 39:1003-18. doi:10.1016/j.immuni.2013.11.010
-
(2013)
Immunity
, vol.39
, pp. 1003-1018
-
-
Garlanda, C.1
Dinarello, C.A.2
Mantovani, A.3
-
3
-
-
30044442866
-
How toll-like receptors signal: what we know and what we don't know
-
O'Neill LA. How toll-like receptors signal: what we know and what we don't know. Curr Opin Immunol (2006) 18:3-9. doi:10.1016/j.coi.2005.11.012
-
(2006)
Curr Opin Immunol
, vol.18
, pp. 3-9
-
-
O'Neill, L.A.1
-
4
-
-
55149105005
-
The interleukin-1 receptor/toll-like receptor superfamily: 10 years of progress
-
O'Neill LA. The interleukin-1 receptor/toll-like receptor superfamily: 10 years of progress. Immunol Rev (2008) 226:10-8. doi:10.1111/j.1600-065X.2008.00701.x
-
(2008)
Immunol Rev
, vol.226
, pp. 10-18
-
-
O'Neill, L.A.1
-
5
-
-
62649139025
-
Immunological and inflammatory functions of the interleukin-1 family
-
Dinarello CA. Immunological and inflammatory functions of the interleukin-1 family. Annu Rev Immunol (2009) 27:519-50. doi:10.1146/annurev.immunol.021908.132612
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 519-550
-
-
Dinarello, C.A.1
-
6
-
-
0025899561
-
A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types
-
McMahan CJ, Slack JL, Mosley B, Cosman D, Lupton SD, Brunton LL, et al. A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types. EMBO J (1991) 10:2821-32
-
(1991)
EMBO J
, vol.10
, pp. 2821-2832
-
-
McMahan, C.J.1
Slack, J.L.2
Mosley, B.3
Cosman, D.4
Lupton, S.D.5
Brunton, L.L.6
-
7
-
-
0027181936
-
Interleukin-1 type II receptor: a decoy target for IL-1 that is regulated by IL-4
-
Colotta F, Re F, Muzio M, Bertini R, Polentarutti N, Sironi M, et al. Interleukin-1 type II receptor: a decoy target for IL-1 that is regulated by IL-4. Science (1993) 261:472-5. doi:10.1126/science.8332913
-
(1993)
Science
, vol.261
, pp. 472-475
-
-
Colotta, F.1
Re, F.2
Muzio, M.3
Bertini, R.4
Polentarutti, N.5
Sironi, M.6
-
8
-
-
84874248044
-
Intracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1alpha, controlling necrosis-induced sterile inflammation
-
Zheng Y, Humphry M, Maguire JJ, Bennett MR, Clarke MC. Intracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1alpha, controlling necrosis-induced sterile inflammation. Immunity (2013) 38:285-95. doi:10.1016/j.immuni.2013.01.008
-
(2013)
Immunity
, vol.38
, pp. 285-295
-
-
Zheng, Y.1
Humphry, M.2
Maguire, J.J.3
Bennett, M.R.4
Clarke, M.C.5
-
9
-
-
18744388579
-
Modulation of toll-interleukin 1 receptor mediated signaling
-
Li X, Qin J. Modulation of toll-interleukin 1 receptor mediated signaling. J Mol Med (Berl) (2005) 83:258-66. doi:10.1007/s00109-004-0622-4
-
(2005)
J Mol Med (Berl)
, vol.83
, pp. 258-266
-
-
Li, X.1
Qin, J.2
-
10
-
-
68949181883
-
TIR8/SIGIRR: an IL-1R/TLR family member with regulatory functions in inflammation and T cell polarization
-
Garlanda C, Anders HJ, Mantovani A. TIR8/SIGIRR: an IL-1R/TLR family member with regulatory functions in inflammation and T cell polarization. Trends Immunol (2009) 30:439-46. doi:10.1016/j.it.2009.06.001
-
(2009)
Trends Immunol
, vol.30
, pp. 439-446
-
-
Garlanda, C.1
Anders, H.J.2
Mantovani, A.3
-
11
-
-
84925671141
-
IL-37 requires the receptors IL-18Ralpha and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction
-
Nold-Petry CA, Lo CY, Rudloff I, Elgass KD, Li S, Gantier MP, et al. IL-37 requires the receptors IL-18Ralpha and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction. Nat Immunol (2015) 16:354-65. doi:10.1038/ni.3103
-
(2015)
Nat Immunol
, vol.16
, pp. 354-365
-
-
Nold-Petry, C.A.1
Lo, C.Y.2
Rudloff, I.3
Elgass, K.D.4
Li, S.5
Gantier, M.P.6
-
12
-
-
0032983336
-
Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response
-
Novick D, Kim SH, Fantuzzi G, Reznikov LL, Dinarello CA, Rubinstein M. Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response. Immunity (1999) 10:127-36. doi:10.1016/S1074-7613(00)80013-8
-
(1999)
Immunity
, vol.10
, pp. 127-136
-
-
Novick, D.1
Kim, S.H.2
Fantuzzi, G.3
Reznikov, L.L.4
Dinarello, C.A.5
Rubinstein, M.6
-
13
-
-
0037109051
-
A complex of the IL-1 homologue IL-1F7b and IL-18-binding protein reduces IL-18 activity
-
Bufler P, Azam T, Gamboni-Robertson F, Reznikov LL, Kumar S, Dinarello CA, et al. A complex of the IL-1 homologue IL-1F7b and IL-18-binding protein reduces IL-18 activity. Proc Natl Acad Sci U S A (2002) 99:13723-8. doi:10.1073/pnas.212519099
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 13723-13728
-
-
Bufler, P.1
Azam, T.2
Gamboni-Robertson, F.3
Reznikov, L.L.4
Kumar, S.5
Dinarello, C.A.6
-
14
-
-
23044470442
-
Evolution of interleukin-18 binding proteins and interleukin-1 receptor, type II proteins
-
Watanabe M, Goto N, Watanabe Y, Nishiguchi S, Shimada K, Yasunga T, et al. Evolution of interleukin-18 binding proteins and interleukin-1 receptor, type II proteins. Int J Mol Med (2005) 15:561-6. doi:10.3892/ijmm.15.4.56
-
(2005)
Int J Mol Med
, vol.15
, pp. 561-566
-
-
Watanabe, M.1
Goto, N.2
Watanabe, Y.3
Nishiguchi, S.4
Shimada, K.5
Yasunga, T.6
-
15
-
-
1842640230
-
Interleukin (IL)-1F6, IL-1F8, and IL-1F9 signal through IL-1Rrp2 and IL-1RAcP to activate the pathway leading to NF-kappaB and MAPKs
-
Towne JE, Garka KE, Renshaw BR, Virca GD, Sims JE. Interleukin (IL)-1F6, IL-1F8, and IL-1F9 signal through IL-1Rrp2 and IL-1RAcP to activate the pathway leading to NF-kappaB and MAPKs. J Biol Chem (2004) 279:13677-88. doi:10.1074/jbc.M400117200
-
(2004)
J Biol Chem
, vol.279
, pp. 13677-13688
-
-
Towne, J.E.1
Garka, K.E.2
Renshaw, B.R.3
Virca, G.D.4
Sims, J.E.5
-
16
-
-
43549123287
-
IL-1F5 mediates anti-inflammatory activity in the brain through induction of IL-4 following interaction with SIGIRR/TIR8
-
Costelloe C, Watson M, Murphy A, McQuillan K, Loscher C, Armstrong ME, et al. IL-1F5 mediates anti-inflammatory activity in the brain through induction of IL-4 following interaction with SIGIRR/TIR8. J Neurochem (2008) 105:1960-9. doi:10.1111/j.1471-4159.2008.05304.x
-
(2008)
J Neurochem
, vol.105
, pp. 1960-1969
-
-
Costelloe, C.1
Watson, M.2
Murphy, A.3
McQuillan, K.4
Loscher, C.5
Armstrong, M.E.6
-
17
-
-
66649121678
-
An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist
-
Aksentijevich I, Masters SL, Ferguson PJ, Dancey P, Frenkel J, van Royen-Kerkhoff A, et al. An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist. N Engl J Med (2009) 360:2426-37. doi:10.1056/NEJMoa0807865
-
(2009)
N Engl J Med
, vol.360
, pp. 2426-2437
-
-
Aksentijevich, I.1
Masters, S.L.2
Ferguson, P.J.3
Dancey, P.4
Frenkel, J.5
van Royen-Kerkhoff, A.6
-
18
-
-
66649113371
-
An autoinflammatory disease due to homozygous deletion of the IL1RN locus
-
Reddy S, Jia S, Geoffrey R, Lorier R, Suchi M, Broeckel U, et al. An autoinflammatory disease due to homozygous deletion of the IL1RN locus. N Engl J Med (2009) 360:2438-44. doi:10.1056/NEJMoa0809568
-
(2009)
N Engl J Med
, vol.360
, pp. 2438-2444
-
-
Reddy, S.1
Jia, S.2
Geoffrey, R.3
Lorier, R.4
Suchi, M.5
Broeckel, U.6
-
19
-
-
0037178785
-
IRAK-M is a negative regulator of toll-like receptor signaling
-
Kobayashi K, Hernandez LD, Galan JE, Janeway CA Jr, Medzhitov R, Flavell RA. IRAK-M is a negative regulator of toll-like receptor signaling. Cell (2002) 110:191-202. doi:10.1016/S0092-8674(02)00827-9
-
(2002)
Cell
, vol.110
, pp. 191-202
-
-
Kobayashi, K.1
Hernandez, L.D.2
Galan, J.E.3
Janeway, C.A.4
Medzhitov, R.5
Flavell, R.A.6
-
20
-
-
0042236366
-
MyD88S, a splice variant of MyD88, differentially modulates NF-kappaB- and AP-1-dependent gene expression
-
Janssens S, Burns K, Vercammen E, Tschopp J, Beyaert R. MyD88S, a splice variant of MyD88, differentially modulates NF-kappaB- and AP-1-dependent gene expression. FEBS Lett (2003) 548:103-7. doi:10.1016/S0014-5793(03)00747-6
-
(2003)
FEBS Lett
, vol.548
, pp. 103-107
-
-
Janssens, S.1
Burns, K.2
Vercammen, E.3
Tschopp, J.4
Beyaert, R.5
-
21
-
-
65249131826
-
Induction and regulatory function of miR-9 in human monocytes and neutrophils exposed to proinflammatory signals
-
Bazzoni F, Rossato M, Fabbri M, Gaudiosi D, Mirolo M, Mori L, et al. Induction and regulatory function of miR-9 in human monocytes and neutrophils exposed to proinflammatory signals. Proc Natl Acad Sci U S A (2009) 106:5282-7. doi:10.1073/pnas.0810909106
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 5282-5287
-
-
Bazzoni, F.1
Rossato, M.2
Fabbri, M.3
Gaudiosi, D.4
Mirolo, M.5
Mori, L.6
-
22
-
-
79960073532
-
A trio of microRNAs that control toll-like receptor signalling
-
Quinn SR, O'Neill LA. A trio of microRNAs that control toll-like receptor signalling. Int Immunol (2011) 23:421-5. doi:10.1093/intimm/dxr034
-
(2011)
Int Immunol
, vol.23
, pp. 421-425
-
-
Quinn, S.R.1
O'Neill, L.A.2
-
23
-
-
80052158908
-
microRNAs and the resolution phase of inflammation in macrophages
-
Alam MM, O'Neill LA. microRNAs and the resolution phase of inflammation in macrophages. Eur J Immunol (2011) 41:2482-5. doi:10.1002/eji.201141740
-
(2011)
Eur J Immunol
, vol.41
, pp. 2482-2485
-
-
Alam, M.M.1
O'Neill, L.A.2
-
24
-
-
33847060965
-
Interleukin-1beta-driven inflammation promotes the development and invasiveness of chemical carcinogen-induced tumors
-
Krelin Y, Voronov E, Dotan S, Elkabets M, Reich E, Fogel M, et al. Interleukin-1beta-driven inflammation promotes the development and invasiveness of chemical carcinogen-induced tumors. Cancer Res (2007) 67:1062-71. doi:10.1158/0008-5472.CAN-06-2956
-
(2007)
Cancer Res
, vol.67
, pp. 1062-1071
-
-
Krelin, Y.1
Voronov, E.2
Dotan, S.3
Elkabets, M.4
Reich, E.5
Fogel, M.6
-
25
-
-
75549087056
-
Disease-associated functions of IL-33: the new kid in the IL-1 family
-
Liew FY, Pitman NI, McInnes IB. Disease-associated functions of IL-33: the new kid in the IL-1 family. Nat Rev Immunol (2010) 10:103-10. doi:10.1038/nri2692
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 103-110
-
-
Liew, F.Y.1
Pitman, N.I.2
McInnes, I.B.3
-
26
-
-
79953813107
-
Interleukin-1 in the pathogenesis and treatment of inflammatory diseases
-
Dinarello CA. Interleukin-1 in the pathogenesis and treatment of inflammatory diseases. Blood (2011) 117:3720-32. doi:10.1182/blood-2010-07-273417
-
(2011)
Blood
, vol.117
, pp. 3720-3732
-
-
Dinarello, C.A.1
-
27
-
-
84865017138
-
IL-36 in psoriasis
-
Towne JE, Sims JE. IL-36 in psoriasis. Curr Opin Pharmacol (2012) 12:486-90. doi:10.1016/j.coph.2012.02.009
-
(2012)
Curr Opin Pharmacol
, vol.12
, pp. 486-490
-
-
Towne, J.E.1
Sims, J.E.2
-
28
-
-
0033151633
-
Identification and characterization of SIGIRR, a molecule representing a novel subtype of the IL-1R superfamily
-
Thomassen E, Renshaw BR, Sims JE. Identification and characterization of SIGIRR, a molecule representing a novel subtype of the IL-1R superfamily. Cytokine (1999) 11:389-99. doi:10.1006/cyto.1998.0452
-
(1999)
Cytokine
, vol.11
, pp. 389-399
-
-
Thomassen, E.1
Renshaw, B.R.2
Sims, J.E.3
-
29
-
-
34447507719
-
Different roles of TiR8/Sigirr on toll-like receptor signaling in intrarenal antigen-presenting cells and tubular epithelial cells
-
Lech M, Garlanda C, Mantovani A, Kirschning CJ, Schlondorff D, Anders HJ. Different roles of TiR8/Sigirr on toll-like receptor signaling in intrarenal antigen-presenting cells and tubular epithelial cells. Kidney Int (2007) 72:182-92. doi:10.1038/sj.ki.5002293
-
(2007)
Kidney Int
, vol.72
, pp. 182-192
-
-
Lech, M.1
Garlanda, C.2
Mantovani, A.3
Kirschning, C.J.4
Schlondorff, D.5
Anders, H.J.6
-
30
-
-
68549126936
-
The expression pattern of TIR8 is conserved among vertebrates
-
Riva F, Polentarutti N, Tribbioli G, Mantovani A, Garlanda C, Turin L. The expression pattern of TIR8 is conserved among vertebrates. Vet Immunol Immunopathol (2009) 131:44-9. doi:10.1016/j.vetimm.2009.03.009
-
(2009)
Vet Immunol Immunopathol
, vol.131
, pp. 44-49
-
-
Riva, F.1
Polentarutti, N.2
Tribbioli, G.3
Mantovani, A.4
Garlanda, C.5
Turin, L.6
-
31
-
-
80052668568
-
Discovery of the DIGIRR gene from teleost fish: a novel toll-IL-1 receptor family member serving as a negative regulator of IL-1 signaling
-
Gu YF, Fang Y, Jin Y, Dong WR, Xiang LX, Shao JZ. Discovery of the DIGIRR gene from teleost fish: a novel toll-IL-1 receptor family member serving as a negative regulator of IL-1 signaling. J Immunol (2011) 187:2514-30. doi:10.4049/jimmunol.1003457
-
(2011)
J Immunol
, vol.187
, pp. 2514-2530
-
-
Gu, Y.F.1
Fang, Y.2
Jin, Y.3
Dong, W.R.4
Xiang, L.X.5
Shao, J.Z.6
-
32
-
-
84952889382
-
human colon tumors express a dominant-negative form of SIGIRR that promotes inflammation and colitis-associated colon cancer in mice
-
Zhao J, Bulek K, Gulen MF, Zepp JA, Karagkounis G, Martin BN, et al. human colon tumors express a dominant-negative form of SIGIRR that promotes inflammation and colitis-associated colon cancer in mice. Gastroenterology (2015) 149:1860.e-71.e. doi:10.1053/j.gastro.2015.08.051
-
(2015)
Gastroenterology
, vol.149
, pp. 1860e-1871e
-
-
Zhao, J.1
Bulek, K.2
Gulen, M.F.3
Zepp, J.A.4
Karagkounis, G.5
Martin, B.N.6
-
33
-
-
1642498347
-
Unique pattern of expression and inhibition of IL-1 signaling by the IL-1 receptor family member TIR8/SIGIRR
-
Polentarutti N, Rol GP, Muzio M, Bosisio D, Camnasio M, Riva F, et al. Unique pattern of expression and inhibition of IL-1 signaling by the IL-1 receptor family member TIR8/SIGIRR. Eur Cytokine Netw (2003) 14:211-8
-
(2003)
Eur Cytokine Netw
, vol.14
, pp. 211-218
-
-
Polentarutti, N.1
Rol, G.P.2
Muzio, M.3
Bosisio, D.4
Camnasio, M.5
Riva, F.6
-
34
-
-
78649287637
-
Down-regulation of single immunoglobulin interleukin-1R-related molecule (SIGIRR)/TIR8 expression in intestinal epithelial cells during inflammation
-
Kadota C, Ishihara S, Aziz MM, Rumi MA, Oshima N, Mishima Y, et al. Down-regulation of single immunoglobulin interleukin-1R-related molecule (SIGIRR)/TIR8 expression in intestinal epithelial cells during inflammation. Clin Exp Immunol (2010) 162:348-61. doi:10.1111/j.1365-2249.2010.04254.x
-
(2010)
Clin Exp Immunol
, vol.162
, pp. 348-361
-
-
Kadota, C.1
Ishihara, S.2
Aziz, M.M.3
Rumi, M.A.4
Oshima, N.5
Mishima, Y.6
-
35
-
-
77951922771
-
The single IgG IL-1-related receptor controls TLR responses in differentiated human intestinal epithelial cells
-
Khan MA, Steiner TS, Sham HP, Bergstrom KS, Huang JT, Assi K, et al. The single IgG IL-1-related receptor controls TLR responses in differentiated human intestinal epithelial cells. J Immunol (2010) 184:2305-13. doi:10.4049/jimmunol.0900021
-
(2010)
J Immunol
, vol.184
, pp. 2305-2313
-
-
Khan, M.A.1
Steiner, T.S.2
Sham, H.P.3
Bergstrom, K.S.4
Huang, J.T.5
Assi, K.6
-
36
-
-
33646507867
-
Microarray analyses of peripheral blood cells identifies unique gene expression signature in psoriatic arthritis
-
Batliwalla FM, Li W, Ritchlin CT, Xiao X, Brenner M, Laragione T, et al. Microarray analyses of peripheral blood cells identifies unique gene expression signature in psoriatic arthritis. Mol Med (2005) 11:21-9. doi:10.2119/2006-00003.Gulko
-
(2005)
Mol Med
, vol.11
, pp. 21-29
-
-
Batliwalla, F.M.1
Li, W.2
Ritchlin, C.T.3
Xiao, X.4
Brenner, M.5
Laragione, T.6
-
37
-
-
34247187130
-
Reduced toll-like receptor 4 expression in children with asymptomatic bacteriuria
-
Ragnarsdottir B, Samuelsson M, Gustafsson MC, Leijonhufvud I, Karpman D, Svanborg C. Reduced toll-like receptor 4 expression in children with asymptomatic bacteriuria. J Infect Dis (2007) 196:475-84. doi:10.1086/518893
-
(2007)
J Infect Dis
, vol.196
, pp. 475-484
-
-
Ragnarsdottir, B.1
Samuelsson, M.2
Gustafsson, M.C.3
Leijonhufvud, I.4
Karpman, D.5
Svanborg, C.6
-
38
-
-
79952825184
-
The mechanism of excessive intestinal inflammation in necrotizing enterocolitis: an immature innate immune response
-
Nanthakumar N, Meng D, Goldstein AM, Zhu W, Lu L, Uauy R, et al. The mechanism of excessive intestinal inflammation in necrotizing enterocolitis: an immature innate immune response. PLoS One (2011) 6:e17776. doi:10.1371/journal.pone.0017776
-
(2011)
PLoS One
, vol.6
-
-
Nanthakumar, N.1
Meng, D.2
Goldstein, A.M.3
Zhu, W.4
Lu, L.5
Uauy, R.6
-
39
-
-
84857098277
-
Role of toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection
-
Veliz Rodriguez T, Moalli F, Polentarutti N, Paroni M, Bonavita E, Anselmo A, et al. Role of toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection. Infect Immun (2012) 80:100-9. doi:10.1128/IAI.05695-11
-
(2012)
Infect Immun
, vol.80
, pp. 100-109
-
-
Veliz Rodriguez, T.1
Moalli, F.2
Polentarutti, N.3
Paroni, M.4
Bonavita, E.5
Anselmo, A.6
-
40
-
-
55349137780
-
Regulation of toll-like receptors in intestinal epithelial cells by stress and Toxoplasma gondii infection
-
Gopal R, Birdsell D, Monroy FP. Regulation of toll-like receptors in intestinal epithelial cells by stress and Toxoplasma gondii infection. Parasite Immunol (2008) 30:563-76. doi:10.1111/j.1365-3024.2008.01055.x
-
(2008)
Parasite Immunol
, vol.30
, pp. 563-576
-
-
Gopal, R.1
Birdsell, D.2
Monroy, F.P.3
-
41
-
-
84867608292
-
The toll interleukin-1 receptor (IL-1R) 8/single Ig domain IL-1R-related molecule modulates the renal response to bacterial infection
-
Leemans JC, Butter LM, Teske GJ, Stroo I, Pulskens WP, Florquin S. The toll interleukin-1 receptor (IL-1R) 8/single Ig domain IL-1R-related molecule modulates the renal response to bacterial infection. Infect Immun (2012) 80:3812-20. doi:10.1128/IAI.00422-12
-
(2012)
Infect Immun
, vol.80
, pp. 3812-3820
-
-
Leemans, J.C.1
Butter, L.M.2
Teske, G.J.3
Stroo, I.4
Pulskens, W.P.5
Florquin, S.6
-
42
-
-
84949205648
-
SIGIRR participates in negative regulation of LPS response and tolerance in human bladder epithelial cells
-
Li D, Zhang X, Chen B. SIGIRR participates in negative regulation of LPS response and tolerance in human bladder epithelial cells. BMC Immunol (2015) 16:73. doi:10.1186/s12865-015-0137-5
-
(2015)
BMC Immunol
, vol.16
, pp. 73
-
-
Li, D.1
Zhang, X.2
Chen, B.3
-
43
-
-
84903545437
-
Lipopolysaccharide decreases single immunoglobulin interleukin-1 receptor-related molecule (SIGIRR) expression by suppressing specificity protein 1 (Sp1) via the toll-like receptor 4 (TLR4)-p38 pathway in monocytes and neutrophils
-
Ueno-Shuto K, Kato K, Tasaki Y, Sato M, Sato K, Uchida Y, et al. Lipopolysaccharide decreases single immunoglobulin interleukin-1 receptor-related molecule (SIGIRR) expression by suppressing specificity protein 1 (Sp1) via the toll-like receptor 4 (TLR4)-p38 pathway in monocytes and neutrophils. J Biol Chem (2014) 289:18097-109. doi:10.1074/jbc.M113.532093
-
(2014)
J Biol Chem
, vol.289
, pp. 18097-18109
-
-
Ueno-Shuto, K.1
Kato, K.2
Tasaki, Y.3
Sato, M.4
Sato, K.5
Uchida, Y.6
-
44
-
-
33747514521
-
Up-regulation of MyD88s and SIGIRR, molecules inhibiting toll-like receptor signaling, in monocytes from septic patients
-
Adib-Conquy M, Adrie C, Fitting C, Gattolliat O, Beyaert R, Cavaillon JM. Up-regulation of MyD88s and SIGIRR, molecules inhibiting toll-like receptor signaling, in monocytes from septic patients. Crit Care Med (2006) 34:2377-85. doi:10.1097/01.CCM.0000233875.93866.88
-
(2006)
Crit Care Med
, vol.34
, pp. 2377-2385
-
-
Adib-Conquy, M.1
Adrie, C.2
Fitting, C.3
Gattolliat, O.4
Beyaert, R.5
Cavaillon, J.M.6
-
45
-
-
64849087206
-
The essential role of single Ig IL-1 receptor-related molecule/toll IL-1R8 in regulation of Th2 immune response
-
Bulek K, Swaidani S, Qin J, Lu Y, Gulen MF, Herjan T, et al. The essential role of single Ig IL-1 receptor-related molecule/toll IL-1R8 in regulation of Th2 immune response. J Immunol (2009) 182:2601-9. doi:10.4049/jimmunol.0802729
-
(2009)
J Immunol
, vol.182
, pp. 2601-2609
-
-
Bulek, K.1
Swaidani, S.2
Qin, J.3
Lu, Y.4
Gulen, M.F.5
Herjan, T.6
-
46
-
-
84862857096
-
Vasoactive intestinal peptide downregulates proinflammatory TLRs while upregulating anti-inflammatory TLRs in the infected cornea
-
Jiang X, McClellan SA, Barrett RP, Zhang Y, Hazlett LD. Vasoactive intestinal peptide downregulates proinflammatory TLRs while upregulating anti-inflammatory TLRs in the infected cornea. J Immunol (2012) 189:269-78. doi:10.4049/jimmunol.1200365
-
(2012)
J Immunol
, vol.189
, pp. 269-278
-
-
Jiang, X.1
McClellan, S.A.2
Barrett, R.P.3
Zhang, Y.4
Hazlett, L.D.5
-
47
-
-
84863539789
-
Immunobiotic Lactobacillus jensenii modulates the toll-like receptor 4-induced inflammatory response via negative regulation in porcine antigen-presenting cells
-
Villena J, Suzuki R, Fujie H, Chiba E, Takahashi T, Tomosada Y, et al. Immunobiotic Lactobacillus jensenii modulates the toll-like receptor 4-induced inflammatory response via negative regulation in porcine antigen-presenting cells. Clin Vaccine Immunol (2012) 19:1038-53. doi:10.1128/CVI.00199-12
-
(2012)
Clin Vaccine Immunol
, vol.19
, pp. 1038-1053
-
-
Villena, J.1
Suzuki, R.2
Fujie, H.3
Chiba, E.4
Takahashi, T.5
Tomosada, Y.6
-
48
-
-
78649403533
-
Differential regulation of toll-like receptor signalling in spleen and Peyer's patch dendritic cells
-
Davies JM, MacSharry J, Shanahan F. Differential regulation of toll-like receptor signalling in spleen and Peyer's patch dendritic cells. Immunology (2010) 131:438-48. doi:10.1111/j.1365-2567.2010.03317.x
-
(2010)
Immunology
, vol.131
, pp. 438-448
-
-
Davies, J.M.1
MacSharry, J.2
Shanahan, F.3
-
49
-
-
84928824107
-
Alpha-TLR2 antibody attenuates the Abeta-mediated inflammatory response in microglia through enhanced expression of SIGIRR
-
Costello DA, Carney DG, Lynch MA. Alpha-TLR2 antibody attenuates the Abeta-mediated inflammatory response in microglia through enhanced expression of SIGIRR. Brain Behav Immun (2015) 46:70-9. doi:10.1016/j.bbi.2015.01.005
-
(2015)
Brain Behav Immun
, vol.46
, pp. 70-79
-
-
Costello, D.A.1
Carney, D.G.2
Lynch, M.A.3
-
50
-
-
77958149102
-
IL-37 is a fundamental inhibitor of innate immunity
-
Nold MF, Nold-Petry CA, Zepp JA, Palmer BE, Bufler P, Dinarello CA. IL-37 is a fundamental inhibitor of innate immunity. Nat Immunol (2010) 11:1014-22. doi:10.1038/ni.1944
-
(2010)
Nat Immunol
, vol.11
, pp. 1014-1022
-
-
Nold, M.F.1
Nold-Petry, C.A.2
Zepp, J.A.3
Palmer, B.E.4
Bufler, P.5
Dinarello, C.A.6
-
51
-
-
84923676031
-
Extracellular forms of IL-37 inhibit innate inflammation in vitro and in vivo but require the IL-1 family decoy receptor IL-1R8
-
Li S, Neff CP, Barber K, Hong J, Luo Y, Azam T, et al. Extracellular forms of IL-37 inhibit innate inflammation in vitro and in vivo but require the IL-1 family decoy receptor IL-1R8. Proc Natl Acad Sci U S A (2015) 112:2497-502. doi:10.1073/pnas.1424626112
-
(2015)
Proc Natl Acad Sci U S A
, vol.112
, pp. 2497-2502
-
-
Li, S.1
Neff, C.P.2
Barber, K.3
Hong, J.4
Luo, Y.5
Azam, T.6
-
52
-
-
84912106429
-
IL-37 inhibits inflammasome activation and disease severity in murine aspergillosis
-
Moretti S, Bozza S, Oikonomou V, Renga G, Casagrande A, Iannitti RG, et al. IL-37 inhibits inflammasome activation and disease severity in murine aspergillosis. PLoS Pathog (2014) 10:e1004462. doi:10.1371/journal.ppat.1004462
-
(2014)
PLoS Pathog
, vol.10
-
-
Moretti, S.1
Bozza, S.2
Oikonomou, V.3
Renga, G.4
Casagrande, A.5
Iannitti, R.G.6
-
53
-
-
84925776039
-
IL-37 requires IL-18Ralpha and SIGIRR/IL-1R8 to diminish allergic airway inflammation in mice
-
Lunding L, Webering S, Vock C, Schroder A, Raedler D, Schaub B, et al. IL-37 requires IL-18Ralpha and SIGIRR/IL-1R8 to diminish allergic airway inflammation in mice. Allergy (2015) 70:366-73. doi:10.1111/all.12566
-
(2015)
Allergy
, vol.70
, pp. 366-373
-
-
Lunding, L.1
Webering, S.2
Vock, C.3
Schroder, A.4
Raedler, D.5
Schaub, B.6
-
54
-
-
84907356510
-
IL-37 protects against obesity-induced inflammation and insulin resistance
-
Ballak DB, van Diepen JA, Moschen AR, Jansen HJ, Hijmans A, Groenhof GJ, et al. IL-37 protects against obesity-induced inflammation and insulin resistance. Nat Commun (2014) 5:4711. doi:10.1038/ncomms5711
-
(2014)
Nat Commun
, vol.5
, pp. 4711
-
-
Ballak, D.B.1
van Diepen, J.A.2
Moschen, A.R.3
Jansen, H.J.4
Hijmans, A.5
Groenhof, G.J.6
-
55
-
-
0042733592
-
SIGIRR, a negative regulator of toll-like receptor-interleukin 1 receptor signaling
-
Wald D, Qin J, Zhao Z, Qian Y, Naramura M, Tian L, et al. SIGIRR, a negative regulator of toll-like receptor-interleukin 1 receptor signaling. Nat Immunol (2003) 4:920-7. doi:10.1038/ni968
-
(2003)
Nat Immunol
, vol.4
, pp. 920-927
-
-
Wald, D.1
Qin, J.2
Zhao, Z.3
Qian, Y.4
Naramura, M.5
Tian, L.6
-
56
-
-
12144287484
-
Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family
-
Garlanda C, Riva F, Polentarutti N, Buracchi C, Sironi M, De Bortoli M, et al. Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family. Proc Natl Acad Sci U S A (2004) 101:3522-6. doi:10.1073/pnas.0308680101
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 3522-3526
-
-
Garlanda, C.1
Riva, F.2
Polentarutti, N.3
Buracchi, C.4
Sironi, M.5
De Bortoli, M.6
-
57
-
-
21644477461
-
SIGIRR inhibits interleukin-1 receptor- and toll-like receptor 4-mediated signaling through different mechanisms
-
Qin J, Qian Y, Yao J, Grace C, Li X. SIGIRR inhibits interleukin-1 receptor- and toll-like receptor 4-mediated signaling through different mechanisms. J Biol Chem (2005) 280:25233-41. doi:10.1074/jbc.M501363200
-
(2005)
J Biol Chem
, vol.280
, pp. 25233-25241
-
-
Qin, J.1
Qian, Y.2
Yao, J.3
Grace, C.4
Li, X.5
-
58
-
-
84941805448
-
A structural view of negative regulation of the toll-like receptor-mediated inflammatory pathway
-
Guven-Maiorov E, Keskin O, Gursoy A, Nussinov R. A structural view of negative regulation of the toll-like receptor-mediated inflammatory pathway. Biophys J (2015) 109:1214-26. doi:10.1016/j.bpj.2015.06.048
-
(2015)
Biophys J
, vol.109
, pp. 1214-1226
-
-
Guven-Maiorov, E.1
Keskin, O.2
Gursoy, A.3
Nussinov, R.4
-
59
-
-
76749092614
-
Inhibition of toll-like receptors TLR4 and 7 signaling pathways by SIGIRR: a computational approach
-
Gong J, Wei T, Stark RW, Jamitzky F, Heckl WM, Anders HJ, et al. Inhibition of toll-like receptors TLR4 and 7 signaling pathways by SIGIRR: a computational approach. J Struct Biol (2010) 169:323-30. doi:10.1016/j.jsb.2009.12.007
-
(2010)
J Struct Biol
, vol.169
, pp. 323-330
-
-
Gong, J.1
Wei, T.2
Stark, R.W.3
Jamitzky, F.4
Heckl, W.M.5
Anders, H.J.6
-
60
-
-
77955350086
-
SIGIRR/TIR-8 is an inhibitor of toll-like receptor signaling in primary human cells and regulates inflammation in models of rheumatoid arthritis
-
Drexler SK, Kong P, Inglis J, Williams RO, Garlanda C, Mantovani A, et al. SIGIRR/TIR-8 is an inhibitor of toll-like receptor signaling in primary human cells and regulates inflammation in models of rheumatoid arthritis. Arthritis Rheum (2010) 62:2249-61. doi:10.1002/art.27517
-
(2010)
Arthritis Rheum
, vol.62
, pp. 2249-2261
-
-
Drexler, S.K.1
Kong, P.2
Inglis, J.3
Williams, R.O.4
Garlanda, C.5
Mantovani, A.6
-
61
-
-
74649086985
-
The receptor SIGIRR suppresses Th17 cell proliferation via inhibition of the interleukin-1 receptor pathway and mTOR kinase activation
-
Gulen MF, Kang Z, Bulek K, Youzhong W, Kim TW, Chen Y, et al. The receptor SIGIRR suppresses Th17 cell proliferation via inhibition of the interleukin-1 receptor pathway and mTOR kinase activation. Immunity (2010) 32:54-66. doi:10.1016/j.immuni.2009.12.003
-
(2010)
Immunity
, vol.32
, pp. 54-66
-
-
Gulen, M.F.1
Kang, Z.2
Bulek, K.3
Youzhong, W.4
Kim, T.W.5
Chen, Y.6
-
62
-
-
77955485057
-
Loss of single immunoglobulin interlukin-1 receptor-related molecule leads to enhanced colonic polyposis in Apc(min) mice
-
Xiao H, Yin W, Khan MA, Gulen MF, Zhou H, Sham HP, et al. Loss of single immunoglobulin interlukin-1 receptor-related molecule leads to enhanced colonic polyposis in Apc(min) mice. Gastroenterology (2010) 139:574-85. doi:10.1053/j.gastro.2010.04.043
-
(2010)
Gastroenterology
, vol.139
, pp. 574-585
-
-
Xiao, H.1
Yin, W.2
Khan, M.A.3
Gulen, M.F.4
Zhou, H.5
Sham, H.P.6
-
63
-
-
38449105679
-
Damping excessive inflammation and tissue damage in Mycobacterium tuberculosis infection by toll IL-1 receptor 8/single Ig IL-1-related receptor, a negative regulator of IL-1/TLR signaling
-
Garlanda C, Di Liberto D, Vecchi A, La Manna MP, Buracchi C, Caccamo N, et al. Damping excessive inflammation and tissue damage in Mycobacterium tuberculosis infection by toll IL-1 receptor 8/single Ig IL-1-related receptor, a negative regulator of IL-1/TLR signaling. J Immunol (2007) 179:3119-25. doi:10.4049/jimmunol.179.5.3119
-
(2007)
J Immunol
, vol.179
, pp. 3119-3125
-
-
Garlanda, C.1
Di Liberto, D.2
Vecchi, A.3
La Manna, M.P.4
Buracchi, C.5
Caccamo, N.6
-
64
-
-
33745303252
-
SIGIRR promotes resistance against Pseudomonas aeruginosa keratitis by down-regulating type-1 immunity and IL-1R1 and TLR4 signaling
-
Huang X, Hazlett LD, Du W, Barrett RP. SIGIRR promotes resistance against Pseudomonas aeruginosa keratitis by down-regulating type-1 immunity and IL-1R1 and TLR4 signaling. J Immunol (2006) 177:548-56. doi:10.4049/jimmunol.177.1.548
-
(2006)
J Immunol
, vol.177
, pp. 548-556
-
-
Huang, X.1
Hazlett, L.D.2
Du, W.3
Barrett, R.P.4
-
65
-
-
44849100683
-
Lack of toll IL-1R8 exacerbates Th17 cell responses in fungal infection
-
Bozza S, Zelante T, Moretti S, Bonifazi P, DeLuca A, D'Angelo C, et al. Lack of toll IL-1R8 exacerbates Th17 cell responses in fungal infection. J Immunol (2008) 180:4022-31. doi:10.4049/jimmunol.180.6.4022
-
(2008)
J Immunol
, vol.180
, pp. 4022-4031
-
-
Bozza, S.1
Zelante, T.2
Moretti, S.3
Bonifazi, P.4
DeLuca, A.5
D'Angelo, C.6
-
66
-
-
78751627946
-
Enhanced expression of single immunoglobulin IL-1 receptor-related molecule ameliorates LPS-induced acute lung injury in mice
-
Chen X, Zhao Y, Wu X, Qian G. Enhanced expression of single immunoglobulin IL-1 receptor-related molecule ameliorates LPS-induced acute lung injury in mice. Shock (2011) 35:198-204. doi:10.1097/SHK.0b013e3181f226f3
-
(2011)
Shock
, vol.35
, pp. 198-204
-
-
Chen, X.1
Zhao, Y.2
Wu, X.3
Qian, G.4
-
67
-
-
84856286185
-
Common polymorphisms in the PKP3-SIGIRR-TMEM16J gene region are associated with susceptibility to tuberculosis
-
Horne DJ, Randhawa AK, Chau TT, Bang ND, Yen NT, Farrar JJ, et al. Common polymorphisms in the PKP3-SIGIRR-TMEM16J gene region are associated with susceptibility to tuberculosis. J Infect Dis (2012) 205:586-94. doi:10.1093/infdis/jir785
-
(2012)
J Infect Dis
, vol.205
, pp. 586-594
-
-
Horne, D.J.1
Randhawa, A.K.2
Chau, T.T.3
Bang, N.D.4
Yen, N.T.5
Farrar, J.J.6
-
68
-
-
84902773460
-
Single immunoglobulin interleukin-1 receptor-related molecule impairs host defense during pneumonia and sepsis caused by Streptococcus pneumoniae
-
Blok DC, van Lieshout MH, Hoogendijk AJ, Florquin S, de Boer OJ, Garlanda C, et al. Single immunoglobulin interleukin-1 receptor-related molecule impairs host defense during pneumonia and sepsis caused by Streptococcus pneumoniae. J Innate Immun (2014) 6:542-52. doi:10.1159/000358239
-
(2014)
J Innate Immun
, vol.6
, pp. 542-552
-
-
Blok, D.C.1
van Lieshout, M.H.2
Hoogendijk, A.J.3
Florquin, S.4
de Boer, O.J.5
Garlanda, C.6
-
69
-
-
84883432951
-
SIGIRR, a negative regulator of TLR/IL-1R signalling promotes microbiota dependent resistance to colonization by enteric bacterial pathogens
-
Sham HP, Yu EY, Gulen MF, Bhinder G, Stahl M, Chan JM, et al. SIGIRR, a negative regulator of TLR/IL-1R signalling promotes microbiota dependent resistance to colonization by enteric bacterial pathogens. PLoS Pathog (2013) 9:e1003539. doi:10.1371/journal.ppat.1003539
-
(2013)
PLoS Pathog
, vol.9
-
-
Sham, H.P.1
Yu, E.Y.2
Gulen, M.F.3
Bhinder, G.4
Stahl, M.5
Chan, J.M.6
-
70
-
-
82255191977
-
TLR-dependent T cell activation in autoimmunity
-
Mills KH. TLR-dependent T cell activation in autoimmunity. Nat Rev Immunol (2011) 11:807-22. doi:10.1038/nri3095
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 807-822
-
-
Mills, K.H.1
-
71
-
-
78649884336
-
IL-33 family members and asthma-bridging innate and adaptive immune responses
-
Lloyd CM. IL-33 family members and asthma-bridging innate and adaptive immune responses. Curr Opin Immunol (2010) 22:800-6. doi:10.1016/j.coi.2010.10.006
-
(2010)
Curr Opin Immunol
, vol.22
, pp. 800-806
-
-
Lloyd, C.M.1
-
72
-
-
33947545388
-
The toll-like receptor adaptor proteins MyD88 and Mal/TIRAP contribute to the inflammatory and destructive processes in a human model of rheumatoid arthritis
-
Sacre SM, Andreakos E, Kiriakidis S, Amjadi P, Lundberg A, Giddins G, et al. The toll-like receptor adaptor proteins MyD88 and Mal/TIRAP contribute to the inflammatory and destructive processes in a human model of rheumatoid arthritis. Am J Pathol (2007) 170:518-25. doi:10.2353/ajpath.2007.060657
-
(2007)
Am J Pathol
, vol.170
, pp. 518-525
-
-
Sacre, S.M.1
Andreakos, E.2
Kiriakidis, S.3
Amjadi, P.4
Lundberg, A.5
Giddins, G.6
-
73
-
-
73649088291
-
Local interleukin-1-driven joint pathology is dependent on toll-like receptor 4 activation
-
Abdollahi-Roodsaz S, Joosten LA, Koenders MI, van den Brand BT, van de Loo FA, van den Berg WB. Local interleukin-1-driven joint pathology is dependent on toll-like receptor 4 activation. Am J Pathol (2009) 175:2004-13. doi:10.2353/ajpath.2009.090262
-
(2009)
Am J Pathol
, vol.175
, pp. 2004-2013
-
-
Abdollahi-Roodsaz, S.1
Joosten, L.A.2
Koenders, M.I.3
van den Brand, B.T.4
van de Loo, F.A.5
van den Berg, W.B.6
-
74
-
-
77649179676
-
The role of toll-like receptors in chronic inflammation
-
Drexler SK, Foxwell BM. The role of toll-like receptors in chronic inflammation. Int J Biochem Cell Biol (2010) 42:506-18. doi:10.1016/j.biocel.2009.10.009
-
(2010)
Int J Biochem Cell Biol
, vol.42
, pp. 506-518
-
-
Drexler, S.K.1
Foxwell, B.M.2
-
75
-
-
84884235625
-
Toll IL-1R8/single Ig IL-1-related receptor regulates psoriasiform inflammation through direct inhibition of innate IL-17A expression by gammadelta T cells
-
Russell SE, Stefanska AM, Kubica M, Horan RM, Mantovani A, Garlanda C, et al. Toll IL-1R8/single Ig IL-1-related receptor regulates psoriasiform inflammation through direct inhibition of innate IL-17A expression by gammadelta T cells. J Immunol (2013) 191:3337-46. doi:10.4049/jimmunol.1300828
-
(2013)
J Immunol
, vol.191
, pp. 3337-3346
-
-
Russell, S.E.1
Stefanska, A.M.2
Kubica, M.3
Horan, R.M.4
Mantovani, A.5
Garlanda, C.6
-
76
-
-
0037061453
-
Chromatin-IgG complexes activate B cells by dual engagement of IgM and toll-like receptors
-
Leadbetter EA, Rifkin IR, Hohlbaum AM, Beaudette BC, Shlomchik MJ, Marshak-Rothstein A. Chromatin-IgG complexes activate B cells by dual engagement of IgM and toll-like receptors. Nature (2002) 416:603-7. doi:10.1038/416603a
-
(2002)
Nature
, vol.416
, pp. 603-607
-
-
Leadbetter, E.A.1
Rifkin, I.R.2
Hohlbaum, A.M.3
Beaudette, B.C.4
Shlomchik, M.J.5
Marshak-Rothstein, A.6
-
77
-
-
34247891509
-
Immunologically active autoantigens: the role of toll-like receptors in the development of chronic inflammatory disease
-
Marshak-Rothstein A, Rifkin IR. Immunologically active autoantigens: the role of toll-like receptors in the development of chronic inflammatory disease. Annu Rev Immunol (2007) 25:419-41. doi:10.1146/annurev.immunol.22.012703.104514
-
(2007)
Annu Rev Immunol
, vol.25
, pp. 419-441
-
-
Marshak-Rothstein, A.1
Rifkin, I.R.2
-
78
-
-
49249109576
-
Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens
-
Lech M, Kulkarni OP, Pfeiffer S, Savarese E, Krug A, Garlanda C, et al. Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens. J Exp Med (2008) 205:1879-88. doi:10.1084/jem.20072646
-
(2008)
J Exp Med
, vol.205
, pp. 1879-1888
-
-
Lech, M.1
Kulkarni, O.P.2
Pfeiffer, S.3
Savarese, E.4
Krug, A.5
Garlanda, C.6
-
79
-
-
77949846853
-
Lack of SIGIRR/TIR8 aggravates hydrocarbon oil-induced lupus nephritis
-
Lech M, Skuginna V, Kulkarni OP, Gong J, Wei T, Stark RW, et al. Lack of SIGIRR/TIR8 aggravates hydrocarbon oil-induced lupus nephritis. J Pathol (2010) 220:596-607. doi:10.1002/path.2678
-
(2010)
J Pathol
, vol.220
, pp. 596-607
-
-
Lech, M.1
Skuginna, V.2
Kulkarni, O.P.3
Gong, J.4
Wei, T.5
Stark, R.W.6
-
80
-
-
84925507437
-
The decreased frequency of SIGIRR-positive CD4+ T cells in peripheral blood of patients with SLE and its correlation with disease activity
-
Wang DY, Su C, Chen GM, Pan HF, Wang FM, Liu GL, et al. The decreased frequency of SIGIRR-positive CD4+ T cells in peripheral blood of patients with SLE and its correlation with disease activity. Mol Biol Rep (2015) 42:423-30. doi:10.1007/s11033-014-3783-4
-
(2015)
Mol Biol Rep
, vol.42
, pp. 423-430
-
-
Wang, D.Y.1
Su, C.2
Chen, G.M.3
Pan, H.F.4
Wang, F.M.5
Liu, G.L.6
-
81
-
-
84865579687
-
The largely normal response to toll-like receptor 7 and 9 stimulation and the enhanced expression of SIGIRR by B cells in systemic lupus erythematosus
-
Zhu YY, Su Y, Li ZG, Zhang Y. The largely normal response to toll-like receptor 7 and 9 stimulation and the enhanced expression of SIGIRR by B cells in systemic lupus erythematosus. PLoS One (2012) 7:e44131. doi:10.1371/journal.pone.0044131
-
(2012)
PLoS One
, vol.7
-
-
Zhu, Y.Y.1
Su, Y.2
Li, Z.G.3
Zhang, Y.4
-
82
-
-
84873208978
-
Association study of IRAK-M and SIGIRR genes with SLE in a large European-descent population
-
Sanchez E, Garcia-Bermudez M, Jimenez-Alonso J, de Ramon E, Sanchez-Roman J, Ortego-Centeno N, et al. Association study of IRAK-M and SIGIRR genes with SLE in a large European-descent population. Lupus (2012) 21:1166-71. doi:10.1177/0961203312449494
-
(2012)
Lupus
, vol.21
, pp. 1166-1171
-
-
Sanchez, E.1
Garcia-Bermudez, M.2
Jimenez-Alonso, J.3
de Ramon, E.4
Sanchez-Roman, J.5
Ortego-Centeno, N.6
-
83
-
-
84918824073
-
Emerging role of SIGIRR rs7396562(T/G) polymorphism in systemic lupus erythematosus in a Chinese population
-
Zhu Y, Wang DG, Yang XK, Tao SS, Huang Q, Pan HF, et al. Emerging role of SIGIRR rs7396562(T/G) polymorphism in systemic lupus erythematosus in a Chinese population. Inflammation (2014) 37:1847-51. doi:10.1007/s10753-014-9916-z
-
(2014)
Inflammation
, vol.37
, pp. 1847-1851
-
-
Zhu, Y.1
Wang, D.G.2
Yang, X.K.3
Tao, S.S.4
Huang, Q.5
Pan, H.F.6
-
84
-
-
27744446058
-
IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines
-
Schmitz J, Owyang A, Oldham E, Song Y, Murphy E, McClanahan TK, et al. IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity (2005) 23:479-90. doi:10.1016/j.immuni.2005.09.015
-
(2005)
Immunity
, vol.23
, pp. 479-490
-
-
Schmitz, J.1
Owyang, A.2
Oldham, E.3
Song, Y.4
Murphy, E.5
McClanahan, T.K.6
-
85
-
-
33646463163
-
An association study of asthma and related phenotypes with polymorphisms in negative regulator molecules of the TLR signaling pathway
-
Nakashima K, Hirota T, Obara K, Shimizu M, Jodo A, Kameda M, et al. An association study of asthma and related phenotypes with polymorphisms in negative regulator molecules of the TLR signaling pathway. J Hum Genet (2006) 51:284-91. doi:10.1007/s10038-005-0358-1
-
(2006)
J Hum Genet
, vol.51
, pp. 284-291
-
-
Nakashima, K.1
Hirota, T.2
Obara, K.3
Shimizu, M.4
Jodo, A.5
Kameda, M.6
-
86
-
-
70349320167
-
Resident dendritic cells prevent postischemic acute renal failure by help of single Ig IL-1 receptor-related protein
-
Lech M, Avila-Ferrufino A, Allam R, Segerer S, Khandoga A, Krombach F, et al. Resident dendritic cells prevent postischemic acute renal failure by help of single Ig IL-1 receptor-related protein. J Immunol (2009) 183:4109-18. doi:10.4049/jimmunol.0900118
-
(2009)
J Immunol
, vol.183
, pp. 4109-4118
-
-
Lech, M.1
Avila-Ferrufino, A.2
Allam, R.3
Segerer, S.4
Khandoga, A.5
Krombach, F.6
-
87
-
-
70449709584
-
The toll-IL-1R member Tir8/SIGIRR negatively regulates adaptive immunity against kidney grafts
-
Noris M, Cassis P, Azzollini N, Cavinato R, Cugini D, Casiraghi F, et al. The toll-IL-1R member Tir8/SIGIRR negatively regulates adaptive immunity against kidney grafts. J Immunol (2009) 183:4249-60. doi:10.4049/jimmunol.0803549
-
(2009)
J Immunol
, vol.183
, pp. 4249-4260
-
-
Noris, M.1
Cassis, P.2
Azzollini, N.3
Cavinato, R.4
Cugini, D.5
Casiraghi, F.6
-
88
-
-
79955531653
-
Toll-like receptor signaling and SIGIRR in renal fibrosis upon unilateral ureteral obstruction
-
Skuginna V, Lech M, Allam R, Ryu M, Clauss S, Susanti HE, et al. Toll-like receptor signaling and SIGIRR in renal fibrosis upon unilateral ureteral obstruction. PLoS One (2011) 6:e19204. doi:10.1371/journal.pone.0019204
-
(2011)
PLoS One
, vol.6
-
-
Skuginna, V.1
Lech, M.2
Allam, R.3
Ryu, M.4
Clauss, S.5
Susanti, H.E.6
-
89
-
-
77951246550
-
Endogenous ligands for TLR2 and TLR4 are not involved in renal injury following ureteric obstruction
-
Chowdhury P, Sacks SH, Sheerin NS. Endogenous ligands for TLR2 and TLR4 are not involved in renal injury following ureteric obstruction. Nephron Exp Nephrol (2010) 115:e122-30. doi:10.1159/000313493
-
(2010)
Nephron Exp Nephrol
, vol.115
, pp. e122-e130
-
-
Chowdhury, P.1
Sacks, S.H.2
Sheerin, N.S.3
-
90
-
-
26844554608
-
Regulation of expression of the novel IL-1 receptor family members in the mouse brain
-
Andre R, Lerouet D, Kimber I, Pinteaux E, Rothwell NJ. Regulation of expression of the novel IL-1 receptor family members in the mouse brain. J Neurochem (2005) 95:324-30. doi:10.1111/j.1471-4159.2005.03364.x
-
(2005)
J Neurochem
, vol.95
, pp. 324-330
-
-
Andre, R.1
Lerouet, D.2
Kimber, I.3
Pinteaux, E.4
Rothwell, N.J.5
-
91
-
-
77954214623
-
SIGIRR modulates the inflammatory response in the brain
-
Watson MB, Costello DA, Carney DG, McQuillan K, Lynch MA. SIGIRR modulates the inflammatory response in the brain. Brain Behav Immun (2010) 24:985-95. doi:10.1016/j.bbi.2010.04.002
-
(2010)
Brain Behav Immun
, vol.24
, pp. 985-995
-
-
Watson, M.B.1
Costello, D.A.2
Carney, D.G.3
McQuillan, K.4
Lynch, M.A.5
-
92
-
-
79952388696
-
Interleukin-1alpha and HMGB1 mediate hippocampal dysfunction in SIGIRR-deficient mice
-
Costello DA, Watson MB, Cowley TR, Murphy N, Murphy Royal C, Garlanda C, et al. Interleukin-1alpha and HMGB1 mediate hippocampal dysfunction in SIGIRR-deficient mice. J Neurosci (2011) 31:3871-9. doi:10.1523/JNEUROSCI.6676-10.2011
-
(2011)
J Neurosci
, vol.31
, pp. 3871-3879
-
-
Costello, D.A.1
Watson, M.B.2
Cowley, T.R.3
Murphy, N.4
Murphy Royal, C.5
Garlanda, C.6
-
93
-
-
34247175428
-
The toll-interleukin-1 receptor member SIGIRR regulates colonic epithelial homeostasis, inflammation, and tumorigenesis
-
Xiao H, Gulen MF, Qin J, Yao J, Bulek K, Kish D, et al. The toll-interleukin-1 receptor member SIGIRR regulates colonic epithelial homeostasis, inflammation, and tumorigenesis. Immunity (2007) 26:461-75. doi:10.1016/j.immuni.2007.02.012
-
(2007)
Immunity
, vol.26
, pp. 461-475
-
-
Xiao, H.1
Gulen, M.F.2
Qin, J.3
Yao, J.4
Bulek, K.5
Kish, D.6
-
94
-
-
34447118220
-
Increased susceptibility to colitis-associated cancer of mice lacking TIR8, an inhibitory member of the interleukin-1 receptor family
-
Garlanda C, Riva F, Veliz T, Polentarutti N, Pasqualini F, Radaelli E, et al. Increased susceptibility to colitis-associated cancer of mice lacking TIR8, an inhibitory member of the interleukin-1 receptor family. Cancer Res (2007) 67:6017-21. doi:10.1158/0008-5472.CAN-07-0560
-
(2007)
Cancer Res
, vol.67
, pp. 6017-6021
-
-
Garlanda, C.1
Riva, F.2
Veliz, T.3
Polentarutti, N.4
Pasqualini, F.5
Radaelli, E.6
-
96
-
-
67650151005
-
Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability
-
Colotta F, Allavena P, Sica A, Garlanda C, Mantovani A. Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability. Carcinogenesis (2009) 30:1073-81. doi:10.1093/carcin/bgp127
-
(2009)
Carcinogenesis
, vol.30
, pp. 1073-1081
-
-
Colotta, F.1
Allavena, P.2
Sica, A.3
Garlanda, C.4
Mantovani, A.5
-
97
-
-
77956976681
-
Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm
-
Biswas SK, Mantovani A. Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm. Nat Immunol (2010) 11:889-96. doi:10.1038/ni.1937
-
(2010)
Nat Immunol
, vol.11
, pp. 889-896
-
-
Biswas, S.K.1
Mantovani, A.2
-
98
-
-
80052014052
-
Inflammation meets cancer, with NF-kappaB as the matchmaker
-
Ben-Neriah Y, Karin M. Inflammation meets cancer, with NF-kappaB as the matchmaker. Nat Immunol (2011) 12:715-23. doi:10.1038/ni.2060
-
(2011)
Nat Immunol
, vol.12
, pp. 715-723
-
-
Ben-Neriah, Y.1
Karin, M.2
-
99
-
-
77149126406
-
The lymphatic system controls intestinal inflammation and inflammation-associated colon cancer through the chemokine decoy receptor D6
-
Vetrano S, Borroni EM, Sarukhan A, Savino B, Bonecchi R, Correale C, et al. The lymphatic system controls intestinal inflammation and inflammation-associated colon cancer through the chemokine decoy receptor D6. Gut (2010) 59:197-206. doi:10.1136/gut.2009.183772
-
(2010)
Gut
, vol.59
, pp. 197-206
-
-
Vetrano, S.1
Borroni, E.M.2
Sarukhan, A.3
Savino, B.4
Bonecchi, R.5
Correale, C.6
-
100
-
-
4644237613
-
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
-
Curiel TJ, Coukos G, Zou L, Alvarez X, Cheng P, Mottram P, et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med (2004) 10:942-9. doi:10.1038/nm1093
-
(2004)
Nat Med
, vol.10
, pp. 942-949
-
-
Curiel, T.J.1
Coukos, G.2
Zou, L.3
Alvarez, X.4
Cheng, P.5
Mottram, P.6
-
101
-
-
33745298519
-
Nuclear factor-kappaB in cancer development and progression
-
Karin M. Nuclear factor-kappaB in cancer development and progression. Nature (2006) 441:431-6. doi:10.1038/nature04870
-
(2006)
Nature
, vol.441
, pp. 431-436
-
-
Karin, M.1
-
102
-
-
32944474237
-
Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer
-
Karin M, Lawrence T, Nizet V. Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer. Cell (2006) 124:823-35. doi:10.1016/j.cell.2006.02.016
-
(2006)
Cell
, vol.124
, pp. 823-835
-
-
Karin, M.1
Lawrence, T.2
Nizet, V.3
-
103
-
-
58549111588
-
Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface
-
Vaishnava S, Behrendt CL, Ismail AS, Eckmann L, Hooper LV. Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface. Proc Natl Acad Sci U S A (2008) 105:20858-63. doi:10.1073/pnas.0808723105
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 20858-20863
-
-
Vaishnava, S.1
Behrendt, C.L.2
Ismail, A.S.3
Eckmann, L.4
Hooper, L.V.5
-
104
-
-
0037112430
-
Microadenomatous lesions involving loss of Apc heterozygosity in the colon of adult Apc(Min/+) mice
-
Yamada Y, Hata K, Hirose Y, Hara A, Sugie S, Kuno T, et al. Microadenomatous lesions involving loss of Apc heterozygosity in the colon of adult Apc(Min/+) mice. Cancer Res (2002) 62:6367-70
-
(2002)
Cancer Res
, vol.62
, pp. 6367-6370
-
-
Yamada, Y.1
Hata, K.2
Hirose, Y.3
Hara, A.4
Sugie, S.5
Kuno, T.6
-
105
-
-
0344826531
-
Colonic polyposis caused by mTOR-mediated chromosomal instability in Apc+/Delta716 Cdx2± compound mutant mice
-
Aoki K, Tamai Y, Horiike S, Oshima M, Taketo MM. Colonic polyposis caused by mTOR-mediated chromosomal instability in Apc+/Delta716 Cdx2± compound mutant mice. Nat Genet (2003) 35:323-30. doi:10.1038/ng1265
-
(2003)
Nat Genet
, vol.35
, pp. 323-330
-
-
Aoki, K.1
Tamai, Y.2
Horiike, S.3
Oshima, M.4
Taketo, M.M.5
-
106
-
-
70350771183
-
The role of toll-like receptors in chronic B-cell malignancies
-
Muzio M, Bertilaccio MT, Simonetti G, Frenquelli M, Caligaris-Cappio F. The role of toll-like receptors in chronic B-cell malignancies. Leuk Lymphoma (2009) 50:1573-80. doi:10.1080/10428190903115410
-
(2009)
Leuk Lymphoma
, vol.50
, pp. 1573-1580
-
-
Muzio, M.1
Bertilaccio, M.T.2
Simonetti, G.3
Frenquelli, M.4
Caligaris-Cappio, F.5
-
107
-
-
58549120954
-
Expression and function of toll like receptors in chronic lymphocytic leukaemia cells
-
Muzio M, Scielzo C, Bertilaccio MT, Frenquelli M, Ghia P, Caligaris-Cappio F. Expression and function of toll like receptors in chronic lymphocytic leukaemia cells. Br J Haematol (2009) 144:507-16. doi:10.1111/j.1365-2141.2008.07475.x
-
(2009)
Br J Haematol
, vol.144
, pp. 507-516
-
-
Muzio, M.1
Scielzo, C.2
Bertilaccio, M.T.3
Frenquelli, M.4
Ghia, P.5
Caligaris-Cappio, F.6
-
108
-
-
80355126549
-
Toll-like receptor signaling pathway in chronic lymphocytic leukemia: distinct gene expression profiles of potential pathogenic significance in specific subsets of patients
-
Arvaniti E, Ntoufa S, Papakonstantinou N, Touloumenidou T, Laoutaris N, Anagnostopoulos A, et al. Toll-like receptor signaling pathway in chronic lymphocytic leukemia: distinct gene expression profiles of potential pathogenic significance in specific subsets of patients. Haematologica (2011) 96:1644-52. doi:10.3324/haematol.2011.044792
-
(2011)
Haematologica
, vol.96
, pp. 1644-1652
-
-
Arvaniti, E.1
Ntoufa, S.2
Papakonstantinou, N.3
Touloumenidou, T.4
Laoutaris, N.5
Anagnostopoulos, A.6
-
109
-
-
0037076279
-
Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression
-
Bichi R, Shinton SA, Martin ES, Koval A, Calin GA, Cesari R, et al. Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression. Proc Natl Acad Sci U S A (2002) 99:6955-60. doi:10.1073/pnas.102181599
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 6955-6960
-
-
Bichi, R.1
Shinton, S.A.2
Martin, E.S.3
Koval, A.4
Calin, G.A.5
Cesari, R.6
-
110
-
-
79960691639
-
Lack of TIR8/SIGIRR triggers progression of chronic lymphocytic leukemia in mouse models
-
Bertilaccio MT, Simonetti G, Dagklis A, Rocchi M, Rodriguez TV, Apollonio B, et al. Lack of TIR8/SIGIRR triggers progression of chronic lymphocytic leukemia in mouse models. Blood (2011) 118:660-9. doi:10.1182/blood-2011-01-329870
-
(2011)
Blood
, vol.118
, pp. 660-669
-
-
Bertilaccio, M.T.1
Simonetti, G.2
Dagklis, A.3
Rocchi, M.4
Rodriguez, T.V.5
Apollonio, B.6
|