-
1
-
-
78149298226
-
Mechanisms of tubulointerstitial fibrosis
-
Zeisberg M, Neilson EG, (2010) Mechanisms of tubulointerstitial fibrosis. J Am Soc Nephrol 21: 1819-1834.
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 1819-1834
-
-
Zeisberg, M.1
Neilson, E.G.2
-
2
-
-
33645452371
-
Chronic hypoxia and tubulointerstitial injury: a final common pathway to end-stage renal failure
-
Nangaku M, (2006) Chronic hypoxia and tubulointerstitial injury: a final common pathway to end-stage renal failure. J Am Soc Nephrol 17: 17-25.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 17-25
-
-
Nangaku, M.1
-
3
-
-
77949351029
-
New insights into epithelial-mesenchymal transition in kidney fibrosis
-
Liu Y, (2010) New insights into epithelial-mesenchymal transition in kidney fibrosis. J Am Soc Nephrol 21: 212-222.
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 212-222
-
-
Liu, Y.1
-
4
-
-
34547419062
-
Fibrocytes: a new insight into kidney fibrosis
-
Wada T, Sakai N, Matsushima K, Kaneko S, (2007) Fibrocytes: a new insight into kidney fibrosis. Kidney Int 72: 269-273.
-
(2007)
Kidney Int
, vol.72
, pp. 269-273
-
-
Wada, T.1
Sakai, N.2
Matsushima, K.3
Kaneko, S.4
-
5
-
-
75749131647
-
Narrative review: fibrotic diseases: cellular and molecular mechanisms and novel therapies
-
Rosenbloom J, Castro SV, Jimenez SA, (2010) Narrative review: fibrotic diseases: cellular and molecular mechanisms and novel therapies. Ann Intern Med 152: 159-166.
-
(2010)
Ann Intern Med
, vol.152
, pp. 159-166
-
-
Rosenbloom, J.1
Castro, S.V.2
Jimenez, S.A.3
-
6
-
-
42649094509
-
Bone marrow-derived progenitor cells and renal fibrosis
-
Ninichuk V, Anders HJ, (2008) Bone marrow-derived progenitor cells and renal fibrosis. Front Biosci 13: 5163-5173.
-
(2008)
Front Biosci
, vol.13
, pp. 5163-5173
-
-
Ninichuk, V.1
Anders, H.J.2
-
7
-
-
47949099098
-
Origin and physiological roles of inflammation
-
Medzhitov R, (2008) Origin and physiological roles of inflammation. Nature 454: 428-435.
-
(2008)
Nature
, vol.454
, pp. 428-435
-
-
Medzhitov, R.1
-
8
-
-
58049200734
-
Innate immunity to pathogens: diversity in receptors for microbial recognition
-
Akira S, (2009) Innate immunity to pathogens: diversity in receptors for microbial recognition. Immunol Rev 227: 5-8.
-
(2009)
Immunol Rev
, vol.227
, pp. 5-8
-
-
Akira, S.1
-
9
-
-
77955597328
-
Toll-like receptors and danger signaling in kidney injury
-
Anders HJ, (2010) Toll-like receptors and danger signaling in kidney injury. J Am Soc Nephrol 21: 1270-1274.
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 1270-1274
-
-
Anders, H.J.1
-
10
-
-
41149118513
-
How dying cells alert the immune system to danger
-
Kono H, Rock KL, (2008) How dying cells alert the immune system to danger. Nat Rev Immunol 8: 279-289.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 279-289
-
-
Kono, H.1
Rock, K.L.2
-
11
-
-
34247272370
-
Toll-like receptors: emerging concepts in kidney disease
-
Anders HJ, Schlondorff D, (2007) Toll-like receptors: emerging concepts in kidney disease. Curr Opin Nephrol Hypertens 16: 177-183.
-
(2007)
Curr Opin Nephrol Hypertens
, vol.16
, pp. 177-183
-
-
Anders, H.J.1
Schlondorff, D.2
-
12
-
-
26444571820
-
Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney
-
Leemans JC, Stokman G, Claessen N, Rouschop KM, Teske GJ, et al. (2005) Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney. J Clin Invest 115: 2894-2903.
-
(2005)
J Clin Invest
, vol.115
, pp. 2894-2903
-
-
Leemans, J.C.1
Stokman, G.2
Claessen, N.3
Rouschop, K.M.4
Teske, G.J.5
-
13
-
-
34948835806
-
TLR4 activation mediates kidney ischemia/reperfusion injury
-
Wu H, Chen G, Wyburn KR, Yin J, Bertolino P, et al. (2007) TLR4 activation mediates kidney ischemia/reperfusion injury. J Clin Invest 117: 2847-2859.
-
(2007)
J Clin Invest
, vol.117
, pp. 2847-2859
-
-
Wu, H.1
Chen, G.2
Wyburn, K.R.3
Yin, J.4
Bertolino, P.5
-
14
-
-
34248140689
-
TLR2 is constitutively expressed within the kidney and participates in ischemic renal injury through both MyD88-dependent and -independent pathways
-
Shigeoka AA, Holscher TD, King AJ, Hall FW, Kiosses WB, et al. (2007) TLR2 is constitutively expressed within the kidney and participates in ischemic renal injury through both MyD88-dependent and-independent pathways. J Immunol 178: 6252-6258.
-
(2007)
J Immunol
, vol.178
, pp. 6252-6258
-
-
Shigeoka, A.A.1
Holscher, T.D.2
King, A.J.3
Hall, F.W.4
Kiosses, W.B.5
-
15
-
-
77951257601
-
Toll-like receptors 2 and 4 in renal ischemia/reperfusion injury
-
Rusai K, Sollinger D, Baumann M, Wagner B, Strobl M, et al. (2010) Toll-like receptors 2 and 4 in renal ischemia/reperfusion injury. Pediatr Nephrol.
-
(2010)
Pediatr Nephrol
-
-
Rusai, K.1
Sollinger, D.2
Baumann, M.3
Wagner, B.4
Strobl, M.5
-
16
-
-
0842321773
-
Role of Toll-like receptor 4 in endotoxin-induced acute renal failure
-
Cunningham PN, Wang Y, Guo R, He G, Quigg RJ, (2004) Role of Toll-like receptor 4 in endotoxin-induced acute renal failure. J Immunol 172: 2629-2635.
-
(2004)
J Immunol
, vol.172
, pp. 2629-2635
-
-
Cunningham, P.N.1
Wang, Y.2
Guo, R.3
He, G.4
Quigg, R.J.5
-
17
-
-
44049103058
-
TLR4 signaling mediates inflammation and tissue injury in nephrotoxicity
-
Zhang B, Ramesh G, Uematsu S, Akira S, Reeves WB, (2008) TLR4 signaling mediates inflammation and tissue injury in nephrotoxicity. J Am Soc Nephrol 19: 923-932.
-
(2008)
J Am Soc Nephrol
, vol.19
, pp. 923-932
-
-
Zhang, B.1
Ramesh, G.2
Uematsu, S.3
Akira, S.4
Reeves, W.B.5
-
18
-
-
45149116776
-
Chloroquine and inhibition of Toll-like receptor 9 protect from sepsis-induced acute kidney injury
-
Yasuda H, Leelahavanichkul A, Tsunoda S, Dear JW, Takahashi Y, et al. (2008) Chloroquine and inhibition of Toll-like receptor 9 protect from sepsis-induced acute kidney injury. Am J Physiol Renal Physiol 294: F1050-1058.
-
(2008)
Am J Physiol Renal Physiol
, vol.294
-
-
Yasuda, H.1
Leelahavanichkul, A.2
Tsunoda, S.3
Dear, J.W.4
Takahashi, Y.5
-
19
-
-
77649204540
-
Recipient Toll-like receptors contribute to chronic graft dysfunction by both MyD88- and TRIF-dependent signaling
-
Wang S, Schmaderer C, Kiss E, Schmidt C, Bonrouhi M, et al. (2010) Recipient Toll-like receptors contribute to chronic graft dysfunction by both MyD88- and TRIF-dependent signaling. Dis Model Mech 3: 92-103.
-
(2010)
Dis Model Mech
, vol.3
, pp. 92-103
-
-
Wang, S.1
Schmaderer, C.2
Kiss, E.3
Schmidt, C.4
Bonrouhi, M.5
-
20
-
-
32644477571
-
Obstructive nephropathy: insights from genetically engineered animals
-
Bascands JL, Schanstra JP, (2005) Obstructive nephropathy: insights from genetically engineered animals. Kidney Int 68: 925-937.
-
(2005)
Kidney Int
, vol.68
, pp. 925-937
-
-
Bascands, J.L.1
Schanstra, J.P.2
-
21
-
-
67349203391
-
Ureteral obstruction as a model of renal interstitial fibrosis and obstructive nephropathy
-
Chevalier RL, Forbes MS, Thornhill BA, (2009) Ureteral obstruction as a model of renal interstitial fibrosis and obstructive nephropathy. Kidney Int 75: 1145-1152.
-
(2009)
Kidney Int
, vol.75
, pp. 1145-1152
-
-
Chevalier, R.L.1
Forbes, M.S.2
Thornhill, B.A.3
-
22
-
-
66349090273
-
The role of Toll-like receptor 2 in inflammation and fibrosis during progressive renal injury
-
Leemans JC, Butter LM, Pulskens WP, Teske GJ, Claessen N, et al. (2009) The role of Toll-like receptor 2 in inflammation and fibrosis during progressive renal injury. PLoS One 4: e5704.
-
(2009)
PLoS One
, vol.4
-
-
Leemans, J.C.1
Butter, L.M.2
Pulskens, W.P.3
Teske, G.J.4
Claessen, N.5
-
23
-
-
79955543675
-
Toll-Like Receptor 4: A Novel Signaling Pathway During Renal Fibrogenesis
-
Campbell MT, Hile KL, Zhang H, Asanuma H, Vanderbrink BA, et al. (2009) Toll-Like Receptor 4: A Novel Signaling Pathway During Renal Fibrogenesis. J Surg Res.
-
(2009)
J Surg Res
-
-
Campbell, M.T.1
Hile, K.L.2
Zhang, H.3
Asanuma, H.4
Vanderbrink, B.A.5
-
24
-
-
46749136412
-
When signaling pathways collide: positive and negative regulation of toll-like receptor signal transduction
-
O'Neill LA, (2008) When signaling pathways collide: positive and negative regulation of toll-like receptor signal transduction. Immunity 29: 12-20.
-
(2008)
Immunity
, vol.29
, pp. 12-20
-
-
O'Neill, L.A.1
-
25
-
-
68949181883
-
TIR8/SIGIRR: an IL-1R/TLR family member with regulatory functions in inflammation and T cell polarization
-
Garlanda C, Anders HJ, Mantovani A, (2009) TIR8/SIGIRR: an IL-1R/TLR family member with regulatory functions in inflammation and T cell polarization. Trends Immunol 30: 439-446.
-
(2009)
Trends Immunol
, vol.30
, pp. 439-446
-
-
Garlanda, C.1
Anders, H.J.2
Mantovani, A.3
-
26
-
-
34447507719
-
Different roles of TiR8/Sigirr on toll-like receptor signaling in intrarenal antigen-presenting cells and tubular epithelial cells
-
Lech M, Garlanda C, Mantovani A, Kirschning CJ, Schlondorff D, et al. (2007) Different roles of TiR8/Sigirr on toll-like receptor signaling in intrarenal antigen-presenting cells and tubular epithelial cells. Kidney Int 72: 182-192.
-
(2007)
Kidney Int
, vol.72
, pp. 182-192
-
-
Lech, M.1
Garlanda, C.2
Mantovani, A.3
Kirschning, C.J.4
Schlondorff, D.5
-
27
-
-
49249109576
-
Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens
-
Lech M, Kulkarni OP, Pfeiffer S, Savarese E, Krug A, et al. (2008) Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens. J Exp Med 205: 1879-1888.
-
(2008)
J Exp Med
, vol.205
, pp. 1879-1888
-
-
Lech, M.1
Kulkarni, O.P.2
Pfeiffer, S.3
Savarese, E.4
Krug, A.5
-
28
-
-
77949846853
-
Lack of SIGIRR/TIR8 aggravates hydrocarbon oil-induced lupus nephritis
-
Lech M, Skuginna V, Kulkarni OP, Gong J, Wei T, et al. (2009) Lack of SIGIRR/TIR8 aggravates hydrocarbon oil-induced lupus nephritis. J Pathol.
-
(2009)
J Pathol
-
-
Lech, M.1
Skuginna, V.2
Kulkarni, O.P.3
Gong, J.4
Wei, T.5
-
29
-
-
70449709584
-
The Toll-IL-1R member Tir8/SIGIRR negatively regulates adaptive immunity against kidney grafts
-
Noris M, Cassis P, Azzollini N, Cavinato R, Cugini D, et al. (2009) The Toll-IL-1R member Tir8/SIGIRR negatively regulates adaptive immunity against kidney grafts. J Immunol 183: 4249-4260.
-
(2009)
J Immunol
, vol.183
, pp. 4249-4260
-
-
Noris, M.1
Cassis, P.2
Azzollini, N.3
Cavinato, R.4
Cugini, D.5
-
30
-
-
70349320167
-
Resident dendritic cells prevent postischemic acute renal failure by help of single Ig IL-1 receptor-related protein
-
Lech M, Avila-Ferrufino A, Allam R, Segerer S, Khandoga A, et al. (2009) Resident dendritic cells prevent postischemic acute renal failure by help of single Ig IL-1 receptor-related protein. J Immunol 183: 4109-4118.
-
(2009)
J Immunol
, vol.183
, pp. 4109-4118
-
-
Lech, M.1
Avila-Ferrufino, A.2
Allam, R.3
Segerer, S.4
Khandoga, A.5
-
31
-
-
35349005817
-
Innate pathogen recognition in the kidney: toll-like receptors, NOD-like receptors, and RIG-like helicases
-
Anders HJ, (2007) Innate pathogen recognition in the kidney: toll-like receptors, NOD-like receptors, and RIG-like helicases. Kidney Int 72: 1051-1056.
-
(2007)
Kidney Int
, vol.72
, pp. 1051-1056
-
-
Anders, H.J.1
-
32
-
-
76749092614
-
Inhibition of Toll-like receptors TLR4 and 7 signaling pathways by SIGIRR: A computational approach
-
Gong J, Wei T, Stark RW, Jamitzky F, Heckl WM, et al. (2009) Inhibition of Toll-like receptors TLR4 and 7 signaling pathways by SIGIRR: A computational approach. J Struct Biol.
-
(2009)
J Struct Biol
-
-
Gong, J.1
Wei, T.2
Stark, R.W.3
Jamitzky, F.4
Heckl, W.M.5
-
33
-
-
32844466826
-
Toll-like receptor-4: renal cells and bone marrow cells signal for neutrophil recruitment during pyelonephritis
-
Patole PS, Schubert S, Hildinger K, Khandoga S, Khandoga A, et al. (2005) Toll-like receptor-4: renal cells and bone marrow cells signal for neutrophil recruitment during pyelonephritis. Kidney Int 68: 2582-2587.
-
(2005)
Kidney Int
, vol.68
, pp. 2582-2587
-
-
Patole, P.S.1
Schubert, S.2
Hildinger, K.3
Khandoga, S.4
Khandoga, A.5
-
34
-
-
77955604860
-
TLR4 promotes fibrosis but attenuates tubular damage in progressive renal injury
-
Pulskens WP, Rampanelli E, Teske GJ, Butter LM, Claessen N, et al. (2010) TLR4 promotes fibrosis but attenuates tubular damage in progressive renal injury. J Am Soc Nephrol 21: 1299-1308.
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 1299-1308
-
-
Pulskens, W.P.1
Rampanelli, E.2
Teske, G.J.3
Butter, L.M.4
Claessen, N.5
-
35
-
-
77951246550
-
Endogenous ligands for TLR2 and TLR4 are not involved in renal injury following ureteric obstruction
-
Chowdhury P, Sacks SH, Sheerin NS, (2010) Endogenous ligands for TLR2 and TLR4 are not involved in renal injury following ureteric obstruction. Nephron Exp Nephrol 115: e122-130.
-
(2010)
Nephron Exp Nephrol
, vol.115
-
-
Chowdhury, P.1
Sacks, S.H.2
Sheerin, N.S.3
-
36
-
-
65949114272
-
Trif is not required for immune complex glomerulonephritis: dying cells activate mesangial cells via Tlr2/Myd88 rather than Tlr3/Trif
-
Lichtnekert J, Vielhauer V, Zecher D, Kulkarni OP, Clauss S, et al. (2009) Trif is not required for immune complex glomerulonephritis: dying cells activate mesangial cells via Tlr2/Myd88 rather than Tlr3/Trif. Am J Physiol Renal Physiol 296: F867-874.
-
(2009)
Am J Physiol Renal Physiol
, vol.296
-
-
Lichtnekert, J.1
Vielhauer, V.2
Zecher, D.3
Kulkarni, O.P.4
Clauss, S.5
-
37
-
-
12144287484
-
Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family
-
Garlanda C, Riva F, Polentarutti N, Buracchi C, Sironi M, et al. (2004) Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family. Proc Natl Acad Sci U S A 101: 3522-3526.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 3522-3526
-
-
Garlanda, C.1
Riva, F.2
Polentarutti, N.3
Buracchi, C.4
Sironi, M.5
-
38
-
-
0033166472
-
Unresponsiveness of MyD88-deficient mice to endotoxin
-
Kawai T, Adachi O, Ogawa T, Takeda K, Akira S, (1999) Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity 11: 115-122.
-
(1999)
Immunity
, vol.11
, pp. 115-122
-
-
Kawai, T.1
Adachi, O.2
Ogawa, T.3
Takeda, K.4
Akira, S.5
-
39
-
-
0033213590
-
Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components
-
Takeuchi O, Hoshino K, Kawai T, Sanjo H, Takada H, et al. (1999) Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. Immunity 11: 443-451.
-
(1999)
Immunity
, vol.11
, pp. 443-451
-
-
Takeuchi, O.1
Hoshino, K.2
Kawai, T.3
Sanjo, H.4
Takada, H.5
-
40
-
-
0034619794
-
A Toll-like receptor recognizes bacterial DNA
-
Hemmi H, Takeuchi O, Kawai T, Kaisho T, Sato S, et al. (2000) A Toll-like receptor recognizes bacterial DNA. Nature 408: 740-745.
-
(2000)
Nature
, vol.408
, pp. 740-745
-
-
Hemmi, H.1
Takeuchi, O.2
Kawai, T.3
Kaisho, T.4
Sato, S.5
-
41
-
-
10744221859
-
DNA oligonucleotide microarray technology identifies fisp-12 among other potential fibrogenic genes following murine unilateral ureteral obstruction (UUO): modulation during epithelial-mesenchymal transition
-
Higgins DF, Lappin DW, Kieran NE, Anders HJ, Watson RW, et al. (2003) DNA oligonucleotide microarray technology identifies fisp-12 among other potential fibrogenic genes following murine unilateral ureteral obstruction (UUO): modulation during epithelial-mesenchymal transition. Kidney Int 64: 2079-2091.
-
(2003)
Kidney Int
, vol.64
, pp. 2079-2091
-
-
Higgins, D.F.1
Lappin, D.W.2
Kieran, N.E.3
Anders, H.J.4
Watson, R.W.5
-
42
-
-
34247892356
-
The role of interstitial macrophages in nephropathy of type 2 diabetic db/db mice
-
Ninichuk V, Khandoga AG, Segerer S, Loetscher P, Schlapbach A, et al. (2007) The role of interstitial macrophages in nephropathy of type 2 diabetic db/db mice. Am J Pathol 170: 1267-1276.
-
(2007)
Am J Pathol
, vol.170
, pp. 1267-1276
-
-
Ninichuk, V.1
Khandoga, A.G.2
Segerer, S.3
Loetscher, P.4
Schlapbach, A.5
-
43
-
-
23844552355
-
Delayed chemokine receptor 1 blockade prolongs survival in collagen 4A3-deficient mice with Alport disease
-
Ninichuk V, Gross O, Reichel C, Khandoga A, Pawar RD, et al. (2005) Delayed chemokine receptor 1 blockade prolongs survival in collagen 4A3-deficient mice with Alport disease. J Am Soc Nephrol 16: 977-985.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 977-985
-
-
Ninichuk, V.1
Gross, O.2
Reichel, C.3
Khandoga, A.4
Pawar, R.D.5
-
44
-
-
0030696753
-
Cells isolated from the human cortical interstitium resemble myofibroblasts and bind neutrophils in an ICAM-1-dependent manner
-
Clayton A, Steadman R, Williams JD, (1997) Cells isolated from the human cortical interstitium resemble myofibroblasts and bind neutrophils in an ICAM-1-dependent manner. J Am Soc Nephrol 8: 604-615.
-
(1997)
J Am Soc Nephrol
, vol.8
, pp. 604-615
-
-
Clayton, A.1
Steadman, R.2
Williams, J.D.3
|