Colonic polyposis caused by mTOR-mediated chromosomal instability in Apc+/Δ716 Cdx2+/- compound mutant mice

Nature Genetics

Volumn 35, Issue 4, 2003, Pages 323-330

  Aoki, Koji ^a   Tamai, Yoshitaka ^b   Horiike, Shigeo ^c   Oshima, Masanobu ^a   Taketo, Makoto M ^a  

^a KYOTO UNIVERSITY   (Japan)

^b TAIHO PHARMACEUTICAL CO LTD   (Japan)

^c KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; APC PROTEIN; COMPLEMENTARY RNA; CYCLIN DEPENDENT KINASE 2; CYCLIN E; PROTEIN KINASE B; PROTEIN P27; RAPAMYCIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CDX2; UNCLASSIFIED DRUG;

ANAPHASE; ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL TISSUE; ARTICLE; CELL CYCLE; CHROMOSOME ABERRATION; COLON MUCOSA; COLON POLYPOSIS; CONTROLLED STUDY; DESCENDING COLON; GENE ACTIVATION; GENE REPRESSION; HETEROZYGOSITY; HUMAN; INTESTINE EPITHELIUM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; TRANSLATION REGULATION; UPREGULATION;

ADENOMATOUS POLYPOSIS COLI PROTEIN; ANAPHASE; ANIMALS; BROMODEOXYURIDINE; CELL SURVIVAL; CELLS, CULTURED; CHROMOSOMAL INSTABILITY; COLONIC NEOPLASMS; COLONIC POLYPS; EPITHELIAL CELLS; FEMALE; G1 PHASE; HETEROZYGOTE; HOMEODOMAIN PROTEINS; HUMANS; IN SITU NICK-END LABELING; LOSS OF HETEROZYGOSITY; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RNA, ANTISENSE; S PHASE; TRANS-ACTIVATORS;

ANIMALIA; MAMMALIA;

EID: 0344826531     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng1265     Document Type: Article

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