Immunobiotic Lactobacillus jensenii modulates the toll-like receptor 4-induced inflammatory response via negative regulation in porcine antigen-presenting cells

Clinical and Vaccine Immunology

Volumn 19, Issue 7, 2012, Pages 1038-1053

  Villena, Julio ^a,b   Suzuki, Rie ^a   Fujie, Hitomi ^a,e   Chiba, Eriko ^a   Takahashi, Takuya ^a   Tomosada, Yohsuke ^a   Shimazu, Tomoyuki ^a   Aso, Hisashi ^a   Ohwada, Shyuichi ^a   Suda, Yoshihito ^c   Ikegami, Shuji ^d   Itoh, Hiroyuki ^d   Alvarez, Susana ^b   Saito, Tadao ^a   Kitazawa, Haruki ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b Reference Centre for Lactobacilli CERELA CONICET   (Argentina)

^c MIYAGI UNIVERSITY   (Japan)

^d MEIJI DAIRIES CORPORATION   (Japan)

^e JOSAI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD172A ANTIGEN; CELL ANTIGEN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 3; INTERLEUKIN 10; PROTEIN A20; REGULATOR PROTEIN; SINGLE IMMUNOGLOBULIN INTERLEUKIN 1 RELATED RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; ARTICLE; BACTERIAL STRAIN; CELL ACTIVITY; CELL ADHESION; CELL ASSAY; CELL ISOLATION; CELL STIMULATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; IMMUNOMODULATION; IN VITRO STUDY; INFLAMMATION; LACTOBACILLUS JENSENII; MICROBIAL ACTIVITY; NEGATIVE FEEDBACK; NONHUMAN; PEYER PATCH; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SWINE; UPREGULATION;

ANIMALS; ANTIGEN-PRESENTING CELLS; CYTOKINES; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LACTOBACILLUS; PEYER'S PATCHES; PROBIOTICS; RECEPTORS, INTERLEUKIN-1; SWINE; TOLL-LIKE RECEPTOR 4;

EID: 84863539789     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00199-12     Document Type: Article

References (42)

1. Abreu MT, Fukata M, Arditi M. 2005. TLR signaling in the gut in health and disease. J. Immunol. 174:4453-4460.
2. Bailey M. 2009. The mucosal immune system: recent developments and future directions in the pig. Dev. Comp. Immunol. 33:375-383.
3. Bimczok D, Sowa EN, Faber-Zuschratter H, Pabst R, Rothkötter HJ. 2005. Site-specific expression of CD11b and SIRPalpha (CD172a) on dendritic cells: implications for their migration patterns in the gut immune system. Eur. J. Immunol. 35:1418-1427. (Pubitemid 40691423)
4. Biswas SK, Lopez-Collazo E. 2009. Endotoxin tolerance: new mechanisms, molecules and clinical significance. Trends Immunol. 30:475-487.
5. Biswas A, Wilmanski J, Forsman H, Hrncir T, Hao LH. 2011. Negative regulation of Toll-like receptor signaling plays an essential role in homeostasis of the intestine. Eur. J. Immunol. 41:182-194.
6. Boone DL, et al. 2004. The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses. Nat. Immunol. 5:1052-1060. (Pubitemid 41057725)
7. Braat H, et al. 2004. Dichotomy between Lactobacillus rhamnosus and Klebsiella pneumoniae on dendritic cell phenotype and function. J. Mol. Med. 82:197-205. (Pubitemid 38392170)
8. Christensen HR, Frøkiaer H, Pestka JJ. 2002. Lactobacilli differentially modulate expression of cytokines and maturation surface markers in murine dendritic cells. J. Immunol. 168:171-178.
9. Clancy R. 2003. Immunobiotics and the probiotic evolution. FEMS Immunol. Med. Microbiol. 38:9-12. (Pubitemid 37297437)
10. Deng JC, et al. 2006. Sepsis-induced suppression of lung innate immunity is mediated by IRAK-M. J. Clin. Invest. 116:2532-2542. (Pubitemid 44330152)
11. Drakes M, Blanchard T, Czinn S. 2004. Bacterial probiotic modulation of dendritic cells. Infect. Immun. 72:3299-3309. (Pubitemid 38697752)
12. Escoll P, et al. 2003. Rapid up-regulation of IRAK-M expression following a second endotoxin challenge in human monocytes and in monocytes isolated from septic patients. Biochem. Biophys. Res. Commun. 311:465-472. (Pubitemid 37340100)
13. Fujie H, et al. 2011. Toll-like receptor-2 activating bifidobacteria strains differentially regulate inflammatory cytokines in porcine intestinal epithelial cell culture system: finding new anti-inflammatory immunobiotics. FEMS Immunol. Med. Microbiol. 63:129-139.
14. Galdeano CM, Perdigón G. 2006. The probiotic bacterium Lactobacillus casei induces activation of the gut mucosal immune system through innate immunity. Clin. Vaccine Immunol. 13:219-226.
15. Hoarau C, Lagaraine C, Martin L, Velge-Roussel F, Lebranchu Y. 2006. Supernatant of Bifidobacterium breve induces dendritic cell maturation, activation, and survival through a Toll-like receptor 2 pathway. J. Allergy Clin. Immunol. 117:696-702. (Pubitemid 43340238)
16. Hosoya S, et al. 2011. Immunobiotic lactic acid bacteria beneficially regulate immune response triggered by poly(I:C) in porcine intestinal epithelial cells. Vet. Res. 42:111.
17. Karlsson H, Larsson P, Wold AE, Rudin A. 2004. Pattern of cytokine responses to gram-positive and gram-negative commensal bacteria is profoundly changed when monocytes differentiate into dendritic cells. Infect. Immun. 72:2671-2678. (Pubitemid 38542393)
18. Kessel A, et al. 2008. Treatment with glutamine is associated with down-regulation of Toll-like receptor-4 and myeloid differentiation factor 88 expression and decrease in intestinal mucosal injury caused by lipopolysaccharide endotoxaemia in a rat. Clin. Exp. Immunol. 151:341-347.
19. Lech M, et al. 2007. Different roles of TiR8/Sigirr on Toll-like receptor signaling in intrarenal antigen-presenting cells and tubular epithelial cells. Kidney Int. 72:182-192. (Pubitemid 47067388)
20. Liew FY, Xu DM, Brint EK, O'Neill LAJ. 2005. Negative regulation of Toll-like receptor-mediated immune responses. Nat. Rev. Immunol. 5:446-458. (Pubitemid 40835033)
21. Macdonald TT, Monteleone G. 2005. Immunity, inflammation and allergy in the gut. Science 307:1920-1925.
22. Mohamadzadeh M, et al. 2005. Lactobacilli activate human dendritic cells that skew T cells toward T helper 1 polarization. Proc. Natl. Acad. Sci. U. S. A. 102:2880-2885. (Pubitemid 40299885)
23. Moue M, et al. 2008. Toll-like receptor 4 and cytokine expression involved in functional immune response in an originally established porcine intestinal epitheliocyte cell line. Biochim. Biophys. Acta 1780:134-144.
24. Nomura F, et al. 2000. Cutting edge: endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface Toll-like receptor 4 expression. J. Immunol. 164:3476-3479. (Pubitemid 30169796)
25. Qin J, Qian Y, Yao J, Grace C, Li X. 2005. SIGIRR inhibits interleukin-1 receptor- and Toll-like receptor 4-mediated signaling through different mechanisms. J. Biol. Chem. 280:25233-25241. (Pubitemid 40934617)
26. Salva S, Villena J, Alvarez S. 2010. Differential immunomodulatory activity of Lactobacillus rhamnosus strains isolated from goat milk: impact on intestinal and respiratory infections. Int. J. Food Microbiol. 141:82-89.
27. Shida K, Kiyoshima-Shibata J, Kaji R, Nagaoka M, Nanno M. 2009. Peptidoglycan from lactobacilli inhibits interleukin-12 production by macrophages induced by Lactobacillus casei through Toll-like receptor 2-dependent and independent mechanisms. Immunology 128:e858-e869. doi:10.1111/j.1365-2567.2009.03095.x.
28. Shimazu T, et al. 2012. Immunobiotic Lactobacillus jensenii elicit anti-inflammatory activity in porcine intestinal epithelial cells by modulating negative regulators of the Toll-like receptor signaling pathway. Infect. Immun. 80:276-288.
29. Shimosato T, et al. 2005. Toll-like receptor 9 is expressed on follicle-associated epithelia containing M cells in swine Peyer's patches. Immunol. Lett. 98:83-89. (Pubitemid 40409822)
30. Summerfield A, McCullough KC. 2009. The porcine dendritic cell family. Dev. Comp. Immunol. 33:299-309.
31. Tohno M, et al. 2005. Toll-like receptor 2 is expressed on the intestinal M cells in swine. Biochem. Biophys. Res. Commun. 330:547-554. (Pubitemid 40417679)
32. Tohno M, et al. 2006. Toll-like receptor 2 and 9 are expressed and functional in gut-associated lymphoid tissues of presuckling newborn swine. Vet. Res. 37:791-812. (Pubitemid 44884290)
33. Tohno M, et al. 2007. Advanced molecular immunoassay system for immunobiotic lactic acid bacteria using a transfectant of Toll-like receptor 2. Anim. Sci. J. 78:195-205. (Pubitemid 46348581)
34. Veckman V, et al. 2004. Streptococcus pyogenes and Lactobacillus rhamnosus differentially induce maturation and production of Th1-type cytokines and chemokines in human monocyte-derived dendritic cells. J. Leukoc. Biol. 75:764-771. (Pubitemid 38580056)
35. Vereecke L, et al. 2010. Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor-induced toxicity and experimental colitis. J. Exp. Med. 207:1513-1523.
36. Villena J, et al. 2005. Lactobacillus casei improves resistance to pneumococcal respiratory infection in malnourished mice. J. Nutr. 135:1462-1469. (Pubitemid 40799611)
37. Villena J, Medina M, Vintiñi E, Alvarez S. 2008. Stimulation of respiratory immunity by oral administration of Lactococcus lactis. Can. J. Microbiol. 54:630-638.
38. Villena J, Aso H, Alvarez S, Kitazawa H. Porcine Toll-like receptors and their crosstalk with immunobiotics: impact in the regulation of gut inflammatory immunity. In Smith A, Jones CL (ed.), Probiotics: sources, types and health benefits, in press. NOVA Science Publishers, Hauppauge, NY.
39. Wen K, et al. 2009. Toll-like receptor and innate cytokine responses induced by lactobacilli colonization and human rotavirus infection in gnotobiotic pigs. Vet. Immunol. Immunopathol. 127:304-315.
40. Werner SL, et al. 2008. Encoding NF-kappa B temporal control in response to TNF: distinct roles for the negative regulators I kappa B alpha and A20. Genes Dev. 22:2093-2101.
41. Zeuthen LH, Fink LN, Frokiaer H. 2008. Toll-like receptor 2 and nucleotide-binding oligomerization domain-2 play divergent roles in the recognition of gut-derived lactobacilli and bifidobacteria in dendritic cells. Immunology 124:489-502. (Pubitemid 351962545)
42. Zhang W, et al. 2008. Lactic acid bacterial colonization and human rotavirus infection influence distribution and frequencies of monocytes/macrophages and dendritic cells in neonatal gnotobiotic pigs. Vet. Immunol. Immunopathol. 121:222-231. (Pubitemid 351163403)