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Volumn 23, Issue 1, 2016, Pages 137-157

Whole-body and Whole-Organ Clearing and Imaging Techniques with Single-Cell Resolution: Toward Organism-Level Systems Biology in Mammals

Author keywords

[No Author keywords available]

Indexed keywords

FLUORESCENT DYE;

EID: 84965037229     PISSN: 24519456     EISSN: 24519448     Source Type: Journal    
DOI: 10.1016/j.chembiol.2015.11.009     Document Type: Review
Times cited : (251)

References (219)
  • 2
    • 84877585171 scopus 로고    scopus 로고
    • Whole-brain functional imaging at cellular resolution using light-sheet microscopy
    • M.B. Ahrens, M.B. Orger, D.N. Robson, J.M. Li, and P.J. Keller Whole-brain functional imaging at cellular resolution using light-sheet microscopy Nat. Methods 10 2013 413 420
    • (2013) Nat. Methods , vol.10 , pp. 413-420
    • Ahrens, M.B.1    Orger, M.B.2    Robson, D.N.3    Li, J.M.4    Keller, P.J.5
  • 4
    • 79951548200 scopus 로고    scopus 로고
    • Challenges and opportunities in mining neuroscience data
    • H. Akil, M.E. Martone, and D.C. Van Essen Challenges and opportunities in mining neuroscience data Science 331 2011 708 712
    • (2011) Science , vol.331 , pp. 708-712
    • Akil, H.1    Martone, M.E.2    Van Essen, D.C.3
  • 8
    • 84944386016 scopus 로고    scopus 로고
    • Efficient processing and analysis of large-scale light-sheet microscopy data
    • F. Amat, B. Hockendorf, Y. Wan, W.C. Lemon, K. McDole, and P.J. Keller Efficient processing and analysis of large-scale light-sheet microscopy data Nat. Protoc. 10 2015 1679 1696
    • (2015) Nat. Protoc. , vol.10 , pp. 1679-1696
    • Amat, F.1    Hockendorf, B.2    Wan, Y.3    Lemon, W.C.4    McDole, K.5    Keller, P.J.6
  • 9
    • 84876467060 scopus 로고    scopus 로고
    • 3D imaging, registration, and analysis of the early mouse embryonic vasculature
    • G.A. Anderson, M.D. Wong, J. Yang, and R.M. Henkelman 3D imaging, registration, and analysis of the early mouse embryonic vasculature Dev. Dyn. 242 2013 527 538
    • (2013) Dev. Dyn. , vol.242 , pp. 527-538
    • Anderson, G.A.1    Wong, M.D.2    Yang, J.3    Henkelman, R.M.4
  • 10
    • 84961288329 scopus 로고    scopus 로고
    • A rapid optical clearing protocol using 2,2'-thiodiethanol for microscopic observation of fixed mouse brain
    • Y. Aoyagi, R. Kawakami, H. Osanai, T. Hibi, and T. Nemoto A rapid optical clearing protocol using 2,2'-thiodiethanol for microscopic observation of fixed mouse brain PLoS One 10 2015 e0116280
    • (2015) PLoS One , vol.10
    • Aoyagi, Y.1    Kawakami, R.2    Osanai, H.3    Hibi, T.4    Nemoto, T.5
  • 11
    • 70449273323 scopus 로고
    • Technique for dissection and measurement of refractive index of osteones
    • A. Ascenzi, and C. Fabry Technique for dissection and measurement of refractive index of osteones J. Biophys. Biochem. Cytol. 6 1959 139 142
    • (1959) J. Biophys. Biochem. Cytol. , vol.6 , pp. 139-142
    • Ascenzi, A.1    Fabry, C.2
  • 12
    • 3242754895 scopus 로고    scopus 로고
    • Alteration of neuronal firing properties after in vivo experience in a FosGFP transgenic mouse
    • A.L. Barth, R.C. Gerkin, and K.L. Dean Alteration of neuronal firing properties after in vivo experience in a FosGFP transgenic mouse J. Neurosci. 24 2004 6466 6475
    • (2004) J. Neurosci. , vol.24 , pp. 6466-6475
    • Barth, A.L.1    Gerkin, R.C.2    Dean, K.L.3
  • 13
    • 84866252908 scopus 로고    scopus 로고
    • Scanned light sheet microscopy with confocal slit detection
    • E. Baumgart, and U. Kubitscheck Scanned light sheet microscopy with confocal slit detection Opt. Express 20 2012 21805 21814
    • (2012) Opt. Express , vol.20 , pp. 21805-21814
    • Baumgart, E.1    Kubitscheck, U.2
  • 14
    • 0027943309 scopus 로고
    • Contribution of the mitochondrial compartment to the optical properties of the rat liver: A theoretical and practical approach
    • B. Beauvoit, T. Kitai, and B. Chance Contribution of the mitochondrial compartment to the optical properties of the rat liver: a theoretical and practical approach Biophys. J. 67 1994 2501 2510
    • (1994) Biophys. J. , vol.67 , pp. 2501-2510
    • Beauvoit, B.1    Kitai, T.2    Chance, B.3
  • 15
  • 16
    • 77249135520 scopus 로고    scopus 로고
    • A novel decalcification method for adult rodent bone for histological analysis of peripheral-central nervous system connections
    • F. Begum, W. Zhu, M.P. Namaka, and E.E. Frost A novel decalcification method for adult rodent bone for histological analysis of peripheral-central nervous system connections J. Neurosci. Methods 187 2010 59 66
    • (2010) J. Neurosci. Methods , vol.187 , pp. 59-66
    • Begum, F.1    Zhu, W.2    Namaka, M.P.3    Frost, E.E.4
  • 18
  • 19
    • 84965048409 scopus 로고    scopus 로고
    • A survey of GPU-based large-scale volume visualization
    • J. Beyer, M. Hadwiger, and H. Pfister A survey of GPU-based large-scale volume visualization Comput. Graph. Forum 34 2015 1337
    • (2015) Comput. Graph. Forum , vol.34 , pp. 1337
    • Beyer, J.1    Hadwiger, M.2    Pfister, H.3
  • 20
    • 84975602245 scopus 로고
    • Refractive-index of some mammalian-tissues using a fiber optic cladding method
    • F.P. Bolin, L.E. Preuss, R.C. Taylor, and R.J. Ference Refractive-index of some mammalian-tissues using a fiber optic cladding method Appl. Opt. 28 1989 2297 2303
    • (1989) Appl. Opt. , vol.28 , pp. 2297-2303
    • Bolin, F.P.1    Preuss, L.E.2    Taylor, R.C.3    Ference, R.J.4
  • 21
    • 84869870968 scopus 로고    scopus 로고
    • TeraStitcher - A tool for fast automatic 3D-stitching of teravoxel-sized microscopy images
    • A. Bria, and G. Iannello TeraStitcher - a tool for fast automatic 3D-stitching of teravoxel-sized microscopy images BMC Bioinformatics 13 2012 316
    • (2012) BMC Bioinformatics , vol.13 , pp. 316
    • Bria, A.1    Iannello, G.2
  • 22
    • 34247552261 scopus 로고    scopus 로고
    • Design and quantitative resolution measurements of an optical virtual sectioning three-dimensional imaging technique for biomedical specimens, featuring two-micrometer slicing resolution
    • J.A. Buytaert, and J.J. Dirckx Design and quantitative resolution measurements of an optical virtual sectioning three-dimensional imaging technique for biomedical specimens, featuring two-micrometer slicing resolution J. Biomed. Opt. 12 2007 014039
    • (2007) J. Biomed. Opt. , vol.12
    • Buytaert, J.A.1    Dirckx, J.J.2
  • 24
    • 0031942569 scopus 로고    scopus 로고
    • Decalcification of bone: Literature review and practical study of various decalcifying agents, methods, and their effects on bone histology
    • G. Callis, and D. Sterchi Decalcification of bone: literature review and practical study of various decalcifying agents, methods, and their effects on bone histology J. Histotechnol. 21 1998 49 58
    • (1998) J. Histotechnol. , vol.21 , pp. 49-58
    • Callis, G.1    Sterchi, D.2
  • 25
    • 84920829434 scopus 로고    scopus 로고
    • Optical clearing in dense connective tissues to visualize cellular connectivity in situ
    • S. Calve, A. Ready, C. Huppenbauer, R. Main, and C.P. Neu Optical clearing in dense connective tissues to visualize cellular connectivity in situ PLoS One 10 2015 e0116662
    • (2015) PLoS One , vol.10
    • Calve, S.1    Ready, A.2    Huppenbauer, C.3    Main, R.4    Neu, C.P.5
  • 26
    • 0043127470 scopus 로고    scopus 로고
    • Patterned vision causes CRE-mediated gene expression in the visual cortex through PKA and ERK
    • L. Cancedda, E. Putignano, S. Impey, L. Maffei, G.M. Ratto, and T. Pizzorusso Patterned vision causes CRE-mediated gene expression in the visual cortex through PKA and ERK J. Neurosci. 23 2003 7012 7020
    • (2003) J. Neurosci. , vol.23 , pp. 7012-7020
    • Cancedda, L.1    Putignano, E.2    Impey, S.3    Maffei, L.4    Ratto, G.M.5    Pizzorusso, T.6
  • 28
    • 0029065706 scopus 로고
    • Effects of solutes on optical properties of biological materials: Models, cells, and tissues
    • B. Chance, H. Liu, T. Kitai, and Y. Zhang Effects of solutes on optical properties of biological materials: models, cells, and tissues Anal. Biochem. 227 1995 351 362
    • (1995) Anal. Biochem. , vol.227 , pp. 351-362
    • Chance, B.1    Liu, H.2    Kitai, T.3    Zhang, Y.4
  • 31
    • 0025551790 scopus 로고
    • A review of the optical-properties of biological tissues
    • W.F. Cheong, S.A. Prahl, and A.J. Welch A review of the optical-properties of biological tissues IEEE J. Quant. Electro. 26 1990 2166 2185
    • (1990) IEEE J. Quant. Electro. , vol.26 , pp. 2166-2185
    • Cheong, W.F.1    Prahl, S.A.2    Welch, A.J.3
  • 32
    • 84949094402 scopus 로고    scopus 로고
    • Whole-animal functional and developmental imaging with isotropic spatial resolution
    • R.K. Chhetri, F. Amat, Y. Wan, B. Hockendorf, W.C. Lemon, and P.J. Keller Whole-animal functional and developmental imaging with isotropic spatial resolution Nat. Methods 12 2015 1171 1178
    • (2015) Nat. Methods , vol.12 , pp. 1171-1178
    • Chhetri, R.K.1    Amat, F.2    Wan, Y.3    Hockendorf, B.4    Lemon, W.C.5    Keller, P.J.6
  • 33
    • 80055063323 scopus 로고    scopus 로고
    • Aqueous Tissue Clearing Solution
    • October U.S. patent
    • A.-S. Chiang Aqueous Tissue Clearing Solution October 2002 U.S. patent 6472216 B1
    • (2002)
    • Chiang, A.-S.1
  • 35
    • 84879753759 scopus 로고    scopus 로고
    • CLARITY for mapping the nervous system
    • K. Chung, and K. Deisseroth CLARITY for mapping the nervous system Nat. Methods 10 2013 508 513
    • (2013) Nat. Methods , vol.10 , pp. 508-513
    • Chung, K.1    Deisseroth, K.2
  • 37
    • 21244441043 scopus 로고    scopus 로고
    • Contrast and depth enhancement in two-photon microscopy of human skin ex vivo by use of optical clearing agents
    • R. Cicchi, D. Sampson, D. Massi, and F. Pavone Contrast and depth enhancement in two-photon microscopy of human skin ex vivo by use of optical clearing agents Opt. Express 13 2005 2337 2344
    • (2005) Opt. Express , vol.13 , pp. 2337-2344
    • Cicchi, R.1    Sampson, D.2    Massi, D.3    Pavone, F.4
  • 38
    • 84862869784 scopus 로고    scopus 로고
    • Medial prefrontal cortex neuronal activation and synaptic alterations after stress-induced reinstatement of palatable food seeking: A study using c-fos-GFP transgenic female rats
    • C. Cifani, E. Koya, B.M. Navarre, D.J. Calu, M.H. Baumann, N.J. Marchant, Q.R. Liu, T. Khuc, J. Pickel, C.R. Lupica, and et al. Medial prefrontal cortex neuronal activation and synaptic alterations after stress-induced reinstatement of palatable food seeking: a study using c-fos-GFP transgenic female rats J. Neurosci. 32 2012 8480 8490
    • (2012) J. Neurosci. , vol.32 , pp. 8480-8490
    • Cifani, C.1    Koya, E.2    Navarre, B.M.3    Calu, D.J.4    Baumann, M.H.5    Marchant, N.J.6    Liu, Q.R.7    Khuc, T.8    Pickel, J.9    Lupica, C.R.10
  • 41
    • 0026101890 scopus 로고
    • Examining pattern formation in mouse, chicken and frog embryos with an En-specific antiserum
    • C.A. Davis, D.P. Holmyard, K.J. Millen, and A.L. Joyner Examining pattern formation in mouse, chicken and frog embryos with an En-specific antiserum Development 111 1991 287 298
    • (1991) Development , vol.111 , pp. 287-298
    • Davis, C.A.1    Holmyard, D.P.2    Millen, K.J.3    Joyner, A.L.4
  • 43
    • 84908192141 scopus 로고    scopus 로고
    • Uniform and scalable light-sheets generated by extended focusing
    • K.M. Dean, and R. Fiolka Uniform and scalable light-sheets generated by extended focusing Opt. Express 22 2014 26141 26152
    • (2014) Opt. Express , vol.22 , pp. 26141-26152
    • Dean, K.M.1    Fiolka, R.2
  • 45
    • 0024579759 scopus 로고
    • A whole-mount immunocytochemical analysis of the expression of the intermediate filament protein vimentin in Xenopus
    • J.A. Dent, A.G. Polson, and M.W. Klymkowsky A whole-mount immunocytochemical analysis of the expression of the intermediate filament protein vimentin in Xenopus Development 105 1989 61 74
    • (1989) Development , vol.105 , pp. 61-74
    • Dent, J.A.1    Polson, A.G.2    Klymkowsky, M.W.3
  • 46
    • 84965013906 scopus 로고    scopus 로고
    • Selective Recovery
    • March U.S. patent
    • B.E. Deverman, and P.H. Patterson Selective Recovery March 2015 U.S. patent 20150079038 A1
    • (2015)
    • Deverman, B.E.1    Patterson, P.H.2
  • 48
    • 58149279268 scopus 로고    scopus 로고
    • In vivo and in vitro visualization of gene expression dynamics over extensive areas of the brain
    • M. Eguchi, and S. Yamaguchi In vivo and in vitro visualization of gene expression dynamics over extensive areas of the brain Neuroimage 44 2009 1274 1283
    • (2009) Neuroimage , vol.44 , pp. 1274-1283
    • Eguchi, M.1    Yamaguchi, S.2
  • 53
    • 84910056830 scopus 로고    scopus 로고
    • Imaging cleared intact biological systems at a cellular level by 3DISCO
    • A. Ertürk, D. Lafkas, and C. Chalouni Imaging cleared intact biological systems at a cellular level by 3DISCO J. Vis. Exp. 89 2014 e51382
    • (2014) J. Vis. Exp. , vol.89
    • Ertürk, A.1    Lafkas, D.2    Chalouni, C.3
  • 55
    • 84856747244 scopus 로고    scopus 로고
    • Propagation stability of self-reconstructing Bessel beams enables contrast-enhanced imaging in thick media
    • F.O. Fahrbach, and A. Rohrbach Propagation stability of self-reconstructing Bessel beams enables contrast-enhanced imaging in thick media Nat. Commun. 3 2012 632
    • (2012) Nat. Commun. , vol.3 , pp. 632
    • Fahrbach, F.O.1    Rohrbach, A.2
  • 56
    • 78049469717 scopus 로고    scopus 로고
    • Microscopy with self-reconstructing beams
    • F.O. Fahrbach, P. Simon, and A. Rohrbach Microscopy with self-reconstructing beams Nat. Photon. 4 2010 780 785
    • (2010) Nat. Photon. , vol.4 , pp. 780-785
    • Fahrbach, F.O.1    Simon, P.2    Rohrbach, A.3
  • 57
    • 84906322330 scopus 로고    scopus 로고
    • Large-scale automated identification of mouse brain cells in confocal light sheet microscopy images
    • P. Frasconi, L. Silvestri, P. Soda, R. Cortini, F.S. Pavone, and G. Iannello Large-scale automated identification of mouse brain cells in confocal light sheet microscopy images Bioinformatics 30 2014 i587 593
    • (2014) Bioinformatics , vol.30 , pp. i587-i593
    • Frasconi, P.1    Silvestri, L.2    Soda, P.3    Cortini, R.4    Pavone, F.S.5    Iannello, G.6
  • 59
    • 79959704485 scopus 로고    scopus 로고
    • STED-SPIM: Stimulated emission depletion improves sheet illumination microscopy resolution
    • M. Friedrich, Q. Gan, V. Ermolayev, and G.S. Harms STED-SPIM: stimulated emission depletion improves sheet illumination microscopy resolution Biophys. J. 100 2011 L43 L45
    • (2011) Biophys. J. , vol.100 , pp. L43-L45
    • Friedrich, M.1    Gan, Q.2    Ermolayev, V.3    Harms, G.S.4
  • 61
    • 84887008084 scopus 로고    scopus 로고
    • GENSAT BAC Cre-recombinase driver lines to study the functional organization of cerebral cortical and basal ganglia circuits
    • C.R. Gerfen, R. Paletzki, and N. Heintz GENSAT BAC Cre-recombinase driver lines to study the functional organization of cerebral cortical and basal ganglia circuits Neuron 80 2013 1368 1383
    • (2013) Neuron , vol.80 , pp. 1368-1383
    • Gerfen, C.R.1    Paletzki, R.2    Heintz, N.3
  • 63
    • 84881127837 scopus 로고    scopus 로고
    • A method for 3D immunostaining and optical imaging of the mouse brain demonstrated in neural progenitor cells
    • J.A. Gleave, J.P. Lerch, R.M. Henkelman, and B.J. Nieman A method for 3D immunostaining and optical imaging of the mouse brain demonstrated in neural progenitor cells PLoS One 8 2013 e72039
    • (2013) PLoS One , vol.8
    • Gleave, J.A.1    Lerch, J.P.2    Henkelman, R.M.3    Nieman, B.J.4
  • 64
    • 37349121061 scopus 로고    scopus 로고
    • Usefulness of a quick decalcification of bone sections embedded in methyl metacrylate: An improved method for immunohistochemistry
    • S.A. Gomes, L.M. dos Reis, I.B. de Oliveira, I.D.L. Noronha, V. Jorgetti, and I.P. Heilberg Usefulness of a quick decalcification of bone sections embedded in methyl metacrylate: an improved method for immunohistochemistry J. Bone Miner. Metab. 26 2008 110 113
    • (2008) J. Bone Miner. Metab. , vol.26 , pp. 110-113
    • Gomes, S.A.1    Dos Reis, L.M.2    De Oliveira, I.B.3    Noronha, I.D.L.4    Jorgetti, V.5    Heilberg, I.P.6
  • 65
    • 34548651693 scopus 로고    scopus 로고
    • Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs
    • S.C. Gong, M. Doughty, C.R. Harbaugh, A. Cummins, M.E. Hatten, N. Heintz, and C.R. Gerfen Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs J. Neurosci. 27 2007 9817 9823
    • (2007) J. Neurosci. , vol.27 , pp. 9817-9823
    • Gong, S.C.1    Doughty, M.2    Harbaugh, C.R.3    Cummins, A.4    Hatten, M.E.5    Heintz, N.6    Gerfen, C.R.7
  • 66
    • 84874990870 scopus 로고    scopus 로고
    • Continuously tracing brain-wide long-distance axonal projections in mice at a one-micron voxel resolution
    • H. Gong, S.Q. Zeng, C. Yan, X.H. Lv, Z.Q. Yang, T.H. Xu, Z. Feng, W.X. Ding, X.L. Qi, A.A. Li, and et al. Continuously tracing brain-wide long-distance axonal projections in mice at a one-micron voxel resolution Neuroimage 74 2013 87 98
    • (2013) Neuroimage , vol.74 , pp. 87-98
    • Gong, H.1    Zeng, S.Q.2    Yan, C.3    Lv, X.H.4    Yang, Z.Q.5    Xu, T.H.6    Feng, Z.7    Ding, W.X.8    Qi, X.L.9    Li, A.A.10
  • 68
    • 84878844344 scopus 로고    scopus 로고
    • Permanent genetic access to transiently active neurons via TRAP: Targeted recombination in active populations
    • C.J. Guenthner, K. Miyamichi, H.H. Yang, H.C. Heller, and L. Luo Permanent genetic access to transiently active neurons via TRAP: targeted recombination in active populations Neuron 78 2013 773 784
    • (2013) Neuron , vol.78 , pp. 773-784
    • Guenthner, C.J.1    Miyamichi, K.2    Yang, H.H.3    Heller, H.C.4    Luo, L.5
  • 71
    • 0032506222 scopus 로고    scopus 로고
    • Dynamics of fluorescence fluctuations in green fluorescent protein observed by fluorescence correlation spectroscopy
    • U. Haupts, S. Maiti, P. Schwille, and W.W. Webb Dynamics of fluorescence fluctuations in green fluorescent protein observed by fluorescence correlation spectroscopy Proc. Natl. Acad. Sci. USA 95 1998 13573 13578
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 13573-13578
    • Haupts, U.1    Maiti, S.2    Schwille, P.3    Webb, W.W.4
  • 72
    • 30944450665 scopus 로고    scopus 로고
    • Deep tissue two-photon microscopy
    • F. Helmchen, and W. Denk Deep tissue two-photon microscopy Nat. Methods 2 2005 932 940
    • (2005) Nat. Methods , vol.2 , pp. 932-940
    • Helmchen, F.1    Denk, W.2
  • 73
    • 84857688652 scopus 로고    scopus 로고
    • Computational methods and challenges for large-scale circuit mapping
    • M. Helmstaedter, and P.P. Mitra Computational methods and challenges for large-scale circuit mapping Curr. Opin. Neurobiol. 22 2012 162 169
    • (2012) Curr. Opin. Neurobiol. , vol.22 , pp. 162-169
    • Helmstaedter, M.1    Mitra, P.P.2
  • 74
    • 79960844955 scopus 로고    scopus 로고
    • High-accuracy neurite reconstruction for high-throughput neuroanatomy
    • M. Helmstaedter, K.L. Briggman, and W. Denk High-accuracy neurite reconstruction for high-throughput neuroanatomy Nat. Neurosci. 14 2011 1081 1088
    • (2011) Nat. Neurosci. , vol.14 , pp. 1081-1088
    • Helmstaedter, M.1    Briggman, K.L.2    Denk, W.3
  • 75
    • 84954231489 scopus 로고    scopus 로고
    • Anatomy of the murine hepatobiliary system: A whole-organ-level analysis using a transparency method
    • Hoboken
    • H. Higashiyama, H. Sumitomo, A. Ozawa, H. Igarashi, N. Tsunekawa, M. Kurohmaru, and Y. Kanai Anatomy of the murine hepatobiliary system: a whole-organ-level analysis using a transparency method Anat. Rec. (Hoboken) 2015 10.1002/ar.23287
    • (2015) Anat. Rec.
    • Higashiyama, H.1    Sumitomo, H.2    Ozawa, A.3    Igarashi, H.4    Tsunekawa, N.5    Kurohmaru, M.6    Kanai, Y.7
  • 76
    • 84942474510 scopus 로고    scopus 로고
    • Procedures for the quantification of whole-tissue immunofluorescence images obtained at single-cell resolution during murine tubular organ development
    • T. Hirashima, and T. Adachi Procedures for the quantification of whole-tissue immunofluorescence images obtained at single-cell resolution during murine tubular organ development PLoS One 10 2015 e0135343
    • (2015) PLoS One , vol.10
    • Hirashima, T.1    Adachi, T.2
  • 77
    • 0000754869 scopus 로고
    • The absorption spectra of hemoglobin and its derivatives in the visible and near infra-red regions
    • B.L. Horecker The absorption spectra of hemoglobin and its derivatives in the visible and near infra-red regions J. Biol. Chem. 148 1943 173 183
    • (1943) J. Biol. Chem. , vol.148 , pp. 173-183
    • Horecker, B.L.1
  • 79
    • 84880270170 scopus 로고    scopus 로고
    • Genetic approaches to neural circuits in the mouse
    • Z.J. Huang, and H. Zeng Genetic approaches to neural circuits in the mouse Annu. Rev. Neurosci. 36 2013 183 215
    • (2013) Annu. Rev. Neurosci. , vol.36 , pp. 183-215
    • Huang, Z.J.1    Zeng, H.2
  • 82
    • 11044221108 scopus 로고    scopus 로고
    • Comparing the synergistic effects of oleic acid and dimethyl sulfoxide as vehicles for optical clearing of skin tissue in vitro
    • J. Jiang, and R.K. Wang Comparing the synergistic effects of oleic acid and dimethyl sulfoxide as vehicles for optical clearing of skin tissue in vitro Phys. Med. Biol. 49 2004 5283 5294
    • (2004) Phys. Med. Biol. , vol.49 , pp. 5283-5294
    • Jiang, J.1    Wang, R.K.2
  • 83
    • 0033591848 scopus 로고    scopus 로고
    • The physical basis of transparency in biological tissue: Ultrastructure and the minimization of light scattering
    • S. Johnsen, and E.A. Widder The physical basis of transparency in biological tissue: ultrastructure and the minimization of light scattering J. Theor. Biol. 199 1999 181 198
    • (1999) J. Theor. Biol. , vol.199 , pp. 181-198
    • Johnsen, S.1    Widder, E.A.2
  • 84
    • 76149089151 scopus 로고    scopus 로고
    • Image contrast enhancement in confocal ultramicroscopy
    • S. Kalchmair, N. Jahrling, K. Becker, and H.U. Dodt Image contrast enhancement in confocal ultramicroscopy Opt. Lett. 35 2010 79 81
    • (2010) Opt. Lett. , vol.35 , pp. 79-81
    • Kalchmair, S.1    Jahrling, N.2    Becker, K.3    Dodt, H.U.4
  • 88
    • 84899141774 scopus 로고    scopus 로고
    • A new era for functional labeling of neurons: Activity-dependent promoters have come of age
    • T. Kawashima, H. Okuno, and H. Bito A new era for functional labeling of neurons: activity-dependent promoters have come of age Front. Neural Circuits 8 2014 37
    • (2014) Front. Neural Circuits , vol.8 , pp. 37
    • Kawashima, T.1    Okuno, H.2    Bito, H.3
  • 89
    • 84880920117 scopus 로고    scopus 로고
    • SeeDB: A simple and morphology-preserving optical clearing agent for neuronal circuit reconstruction
    • M.T. Ke, S. Fujimoto, and T. Imai SeeDB: a simple and morphology-preserving optical clearing agent for neuronal circuit reconstruction Nat. Neurosci. 16 2013 1154 1161
    • (2013) Nat. Neurosci. , vol.16 , pp. 1154-1161
    • Ke, M.T.1    Fujimoto, S.2    Imai, T.3
  • 90
    • 84922021732 scopus 로고    scopus 로고
    • Visualizing whole-brain activity and development at the single-cell level using light-sheet microscopy
    • P.J. Keller, and M.B. Ahrens Visualizing whole-brain activity and development at the single-cell level using light-sheet microscopy Neuron 85 2015 462 483
    • (2015) Neuron , vol.85 , pp. 462-483
    • Keller, P.J.1    Ahrens, M.B.2
  • 91
    • 84857687847 scopus 로고    scopus 로고
    • Light sheet microscopy of living or cleared specimens
    • P.J. Keller, and H.U. Dodt Light sheet microscopy of living or cleared specimens Curr. Opin. Neurobiol. 22 2012 138 143
    • (2012) Curr. Opin. Neurobiol. , vol.22 , pp. 138-143
    • Keller, P.J.1    Dodt, H.U.2
  • 92
    • 56449123775 scopus 로고    scopus 로고
    • Reconstruction of zebrafish early embryonic development by scanned light sheet microscopy
    • P.J. Keller, A.D. Schmidt, J. Wittbrodt, and E.H.K. Stelzer Reconstruction of zebrafish early embryonic development by scanned light sheet microscopy Science 322 2008 1065 1069
    • (2008) Science , vol.322 , pp. 1065-1069
    • Keller, P.J.1    Schmidt, A.D.2    Wittbrodt, J.3    Stelzer, E.H.K.4
  • 93
    • 77955172060 scopus 로고    scopus 로고
    • Fast, high-contrast imaging of animal development with scanned light sheet-based structured-illumination microscopy
    • P.J. Keller, A.D. Schmidt, A. Santella, K. Khairy, Z.R. Bao, J. Wittbrodt, and E.H.K. Stelzer Fast, high-contrast imaging of animal development with scanned light sheet-based structured-illumination microscopy Nat. Methods 7 2010 637 642
    • (2010) Nat. Methods , vol.7 , pp. 637-642
    • Keller, P.J.1    Schmidt, A.D.2    Santella, A.3    Khairy, K.4    Bao, Z.R.5    Wittbrodt, J.6    Stelzer, E.H.K.7
  • 94
    • 84856418376 scopus 로고    scopus 로고
    • MGRASP enables mapping mammalian synaptic connectivity with light microscopy
    • J. Kim, T. Zhao, R.S. Petralia, Y. Yu, H. Peng, E. Myers, and J.C. Magee mGRASP enables mapping mammalian synaptic connectivity with light microscopy Nat. Methods 9 2012 96 102
    • (2012) Nat. Methods , vol.9 , pp. 96-102
    • Kim, J.1    Zhao, T.2    Petralia, R.S.3    Yu, Y.4    Peng, H.5    Myers, E.6    Magee, J.C.7
  • 97
    • 0036500993 scopus 로고    scopus 로고
    • Systems biology: A brief overview
    • H. Kitano Systems biology: a brief overview Science 295 2002 1662 1664
    • (2002) Science , vol.295 , pp. 1662-1664
    • Kitano, H.1
  • 98
    • 77952031756 scopus 로고    scopus 로고
    • Three inhibitors of FGF receptor, ERK, and GSK3 establishes germline-competent embryonic stem cells of C57BL/6N mouse strain with high efficiency and stability
    • H. Kiyonari, M. Kaneko, S. Abe, and S. Aizawa Three inhibitors of FGF receptor, ERK, and GSK3 establishes germline-competent embryonic stem cells of C57BL/6N mouse strain with high efficiency and stability Genesis 48 2010 317 327
    • (2010) Genesis , vol.48 , pp. 317-327
    • Kiyonari, H.1    Kaneko, M.2    Abe, S.3    Aizawa, S.4
  • 100
    • 2542461592 scopus 로고    scopus 로고
    • Changes in trout hemoglobin conformations and solubility after exposure to acid and alkali pH
    • H.G. Kristinsson, and H.O. Hultin Changes in trout hemoglobin conformations and solubility after exposure to acid and alkali pH J. Agric. Food Chem. 52 2004 3633 3643
    • (2004) J. Agric. Food Chem. , vol.52 , pp. 3633-3643
    • Kristinsson, H.G.1    Hultin, H.O.2
  • 102
    • 84949445911 scopus 로고    scopus 로고
    • ClearSee: A rapid optical clearing reagent for whole-plant fluorescence imaging
    • D. Kurihara, Y. Mizuta, Y. Sato, and T. Higashiyama ClearSee: a rapid optical clearing reagent for whole-plant fluorescence imaging Development 142 2015 4168 4179
    • (2015) Development , vol.142 , pp. 4168-4179
    • Kurihara, D.1    Mizuta, Y.2    Sato, Y.3    Higashiyama, T.4
  • 106
    • 84964315043 scopus 로고    scopus 로고
    • Improved application of the electrophoretic tissue clearing technology, CLARITY, to intact solid organs including brain, pancreas, liver, kidney, lung, and intestine
    • H. Lee, J.H. Park, I. Seo, S.H. Park, and S. Kim Improved application of the electrophoretic tissue clearing technology, CLARITY, to intact solid organs including brain, pancreas, liver, kidney, lung, and intestine BMC Dev. Biol. 14 2014 48
    • (2014) BMC Dev. Biol. , vol.14 , pp. 48
    • Lee, H.1    Park, J.H.2    Seo, I.3    Park, S.H.4    Kim, S.5
  • 108
    • 66749184650 scopus 로고    scopus 로고
    • Resolution of ultramicroscopy and field of view analysis
    • U. Leischner, W. Zieglgansberger, and H.U. Dodt Resolution of ultramicroscopy and field of view analysis PLoS One 4 2009 e5785
    • (2009) PLoS One , vol.4
    • Leischner, U.1    Zieglgansberger, W.2    Dodt, H.U.3
  • 111
    • 78649694219 scopus 로고    scopus 로고
    • Micro-optical sectioning tomography to obtain a high-resolution atlas of the mouse brain
    • A.A. Li, H. Gong, B. Zhang, Q.D. Wang, C. Yan, J.P. Wu, Q.A. Liu, S.Q. Zeng, and Q.M. Luo Micro-optical sectioning tomography to obtain a high-resolution atlas of the mouse brain Science 330 2010 1404 1408
    • (2010) Science , vol.330 , pp. 1404-1408
    • Li, A.A.1    Gong, H.2    Zhang, B.3    Wang, Q.D.4    Yan, C.5    Wu, J.P.6    Liu, Q.A.7    Zeng, S.Q.8    Luo, Q.M.9
  • 112
    • 84930226026 scopus 로고    scopus 로고
    • Fast immuno-labeling by electrophoretically driven infiltration for intact tissue imaging
    • J. Li, D.M. Czajkowsky, X. Li, and Z. Shao Fast immuno-labeling by electrophoretically driven infiltration for intact tissue imaging Sci. Rep. 5 2015 10640
    • (2015) Sci. Rep. , vol.5
    • Li, J.1    Czajkowsky, D.M.2    Li, X.3    Shao, Z.4
  • 113
    • 0000299279 scopus 로고    scopus 로고
    • Dependence of tissue optical properties on solute-induced changes in refractive index and osmolarity
    • H. Liu, B. Beauvoit, M. Kimura, and B. Chance Dependence of tissue optical properties on solute-induced changes in refractive index and osmolarity J. Biomed. Opt. 1 1996 200 211
    • (1996) J. Biomed. Opt. , vol.1 , pp. 200-211
    • Liu, H.1    Beauvoit, B.2    Kimura, M.3    Chance, B.4
  • 114
  • 115
    • 40249084139 scopus 로고    scopus 로고
    • Genetic dissection of neural circuits
    • L. Luo, E.M. Callaway, and K. Svoboda Genetic dissection of neural circuits Neuron 57 2008 634 660
    • (2008) Neuron , vol.57 , pp. 634-660
    • Luo, L.1    Callaway, E.M.2    Svoboda, K.3
  • 116
    • 0031844426 scopus 로고    scopus 로고
    • Procedures for whole-mount immunohistochemistry and in situ hybridization of immature mammalian CNS
    • J.M. Luque, W.B. Adams, and J.G. Nicholls Procedures for whole-mount immunohistochemistry and in situ hybridization of immature mammalian CNS Brain Res. Brain Res. Protoc. 2 1998 165 173
    • (1998) Brain Res. Brain Res. Protoc. , vol.2 , pp. 165-173
    • Luque, J.M.1    Adams, W.B.2    Nicholls, J.G.3
  • 117
    • 0031982957 scopus 로고    scopus 로고
    • Three-dimensional visualization of the distribution, growth, and regeneration of monoaminergic neurons in whole mounts of immature mammalian CNS
    • J.M. Luque, V. Biou, and J.G. Nicholls Three-dimensional visualization of the distribution, growth, and regeneration of monoaminergic neurons in whole mounts of immature mammalian CNS J. Comp. Neurol. 390 1998 427 438
    • (1998) J. Comp. Neurol. , vol.390 , pp. 427-438
    • Luque, J.M.1    Biou, V.2    Nicholls, J.G.3
  • 119
    • 49649111688 scopus 로고    scopus 로고
    • Influence of alcohols on the optical clearing effect of skin in vitro
    • Z. Mao, D. Zhu, Y. Hu, X. Wen, and Z. Han Influence of alcohols on the optical clearing effect of skin in vitro J. Biomed. Opt. 13 2008 021104
    • (2008) J. Biomed. Opt. , vol.13
    • Mao, Z.1    Zhu, D.2    Hu, Y.3    Wen, X.4    Han, Z.5
  • 120
    • 84948578004 scopus 로고    scopus 로고
    • High-throughput fluorescence imaging approaches for drug discovery using in vitro and in vivo three-dimensional models
    • N.J. Martinez, S.A. Titus, A.K. Wagner, and A. Simeonov High-throughput fluorescence imaging approaches for drug discovery using in vitro and in vivo three-dimensional models Expert Opin. Drug Discov. 10 2015 1347 1361
    • (2015) Expert Opin. Drug Discov. , vol.10 , pp. 1347-1361
    • Martinez, N.J.1    Titus, S.A.2    Wagner, A.K.3    Simeonov, A.4
  • 122
    • 67649405197 scopus 로고    scopus 로고
    • In toto imaging of embryogenesis with confocal time-lapse microscopy
    • S.G. Megason In toto imaging of embryogenesis with confocal time-lapse microscopy Methods Mol. Biol. 546 2009 317 332
    • (2009) Methods Mol. Biol. , vol.546 , pp. 317-332
    • Megason, S.G.1
  • 124
    • 84975598439 scopus 로고
    • Light scattering from biological cells: Dependence of backscatter radiation on membrane thickness and refractive index
    • R.A. Meyer Light scattering from biological cells: dependence of backscatter radiation on membrane thickness and refractive index Appl. Opt. 18 1979 585 588
    • (1979) Appl. Opt. , vol.18 , pp. 585-588
    • Meyer, R.A.1
  • 125
    • 84930182225 scopus 로고    scopus 로고
    • High-resolution whole-brain staining for electron microscopic circuit reconstruction
    • S. Mikula, and W. Denk High-resolution whole-brain staining for electron microscopic circuit reconstruction Nat. Methods 12 2015 541 546
    • (2015) Nat. Methods , vol.12 , pp. 541-546
    • Mikula, S.1    Denk, W.2
  • 126
    • 84938535774 scopus 로고    scopus 로고
    • Brain clearing for connectomics
    • Oxf.
    • A. Miyawaki Brain clearing for connectomics Microscopy (Oxf.) 64 2015 5 8
    • (2015) Microscopy , vol.64 , pp. 5-8
    • Miyawaki, A.1
  • 127
    • 0000415614 scopus 로고    scopus 로고
    • Mechanisms of light scattering from biological cells relevant to noninvasive optical-tissue diagnostics
    • J.R. Mourant, J.P. Freyer, A.H. Hielscher, A.A. Eick, D. Shen, and T.M. Johnson Mechanisms of light scattering from biological cells relevant to noninvasive optical-tissue diagnostics Appl. Opt. 37 1998 3586 3593
    • (1998) Appl. Opt. , vol.37 , pp. 3586-3593
    • Mourant, J.R.1    Freyer, J.P.2    Hielscher, A.H.3    Eick, A.A.4    Shen, D.5    Johnson, T.M.6
  • 130
    • 84940551571 scopus 로고    scopus 로고
    • Seeing the forest and trees: Whole-body and whole-brain imaging for circadian biology
    • K.L. Ode, and H.R. Ueda Seeing the forest and trees: whole-body and whole-brain imaging for circadian biology Diabetes Obes. Metab. 17 Suppl 1 2015 47 54
    • (2015) Diabetes Obes. Metab. , vol.17 , pp. 47-54
    • Ode, K.L.1    Ueda, H.R.2
  • 132
    • 0034283507 scopus 로고    scopus 로고
    • In vitro simultaneous measurement of refractive index and thickness of biological tissue by the low coherence interferometry
    • M. Ohmi, Y. Ohnishi, K. Yoden, and M. Haruna In vitro simultaneous measurement of refractive index and thickness of biological tissue by the low coherence interferometry IEEE Trans. Biomed. Eng. 47 2000 1266 1270
    • (2000) IEEE Trans. Biomed. Eng. , vol.47 , pp. 1266-1270
    • Ohmi, M.1    Ohnishi, Y.2    Yoden, K.3    Haruna, M.4
  • 133
    • 49649114634 scopus 로고    scopus 로고
    • Optical clearing of unsectioned specimens for three-dimensional imaging via optical transmission and emission tomography
    • M. Oldham, H. Sakhalkar, T. Oliver, G. Allan Johnson, and M. Dewhirst Optical clearing of unsectioned specimens for three-dimensional imaging via optical transmission and emission tomography J. Biomed. Opt. 13 2008 021113
    • (2008) J. Biomed. Opt. , vol.13
    • Oldham, M.1    Sakhalkar, H.2    Oliver, T.3    Allan Johnson, G.4    Dewhirst, M.5
  • 135
    • 84888338781 scopus 로고    scopus 로고
    • Design and generation of recombinant rabies virus vectors
    • F. Osakada, and E.M. Callaway Design and generation of recombinant rabies virus vectors Nat. Protoc. 8 2013 1583 1601
    • (2013) Nat. Protoc. , vol.8 , pp. 1583-1601
    • Osakada, F.1    Callaway, E.M.2
  • 136
    • 84880800347 scopus 로고    scopus 로고
    • Mapping brain circuitry with a light microscope
    • P. Osten, and T.W. Margrie Mapping brain circuitry with a light microscope Nat. Methods 10 2013 515 523
    • (2013) Nat. Methods , vol.10 , pp. 515-523
    • Osten, P.1    Margrie, T.W.2
  • 137
    • 84875497075 scopus 로고    scopus 로고
    • Fast functional imaging of multiple brain regions in intact zebrafish larvae using selective plane illumination microscopy
    • T. Panier, S.A. Romano, R. Olive, T. Pietri, G. Sumbre, R. Candelier, and G. Debregeas Fast functional imaging of multiple brain regions in intact zebrafish larvae using selective plane illumination microscopy Front. Neural Circuits 7 2013 65
    • (2013) Front. Neural Circuits , vol.7 , pp. 65
    • Panier, T.1    Romano, S.A.2    Olive, R.3    Pietri, T.4    Sumbre, G.5    Candelier, R.6    Debregeas, G.7
  • 138
    • 77950679704 scopus 로고    scopus 로고
    • V3D enables real-time 3D visualization and quantitative analysis of large-scale biological image data sets
    • H. Peng, Z. Ruan, F. Long, J.H. Simpson, and E.W. Myers V3D enables real-time 3D visualization and quantitative analysis of large-scale biological image data sets Nat. Biotechnol. 28 2010 348 353
    • (2010) Nat. Biotechnol. , vol.28 , pp. 348-353
    • Peng, H.1    Ruan, Z.2    Long, F.3    Simpson, J.H.4    Myers, E.W.5
  • 139
    • 84930153987 scopus 로고    scopus 로고
    • BigDataViewer: Visualization and processing for large image data sets
    • T. Pietzsch, S. Saalfeld, S. Preibisch, and P. Tomancak BigDataViewer: visualization and processing for large image data sets Nat. Methods 12 2015 481 483
    • (2015) Nat. Methods , vol.12 , pp. 481-483
    • Pietzsch, T.1    Saalfeld, S.2    Preibisch, S.3    Tomancak, P.4
  • 142
    • 84896282038 scopus 로고    scopus 로고
    • Whole-brain activity maps reveal stereotyped, distributed networks for visuomotor behavior
    • R. Portugues, C.E. Feierstein, F. Engert, and M.B. Orger Whole-brain activity maps reveal stereotyped, distributed networks for visuomotor behavior Neuron 81 2014 1328 1343
    • (2014) Neuron , vol.81 , pp. 1328-1343
    • Portugues, R.1    Feierstein, C.E.2    Engert, F.3    Orger, M.B.4
  • 143
    • 0030612109 scopus 로고    scopus 로고
    • A comparison of 3H-cocaine binding on melanin granules and human hair in vitro
    • L. Potsch, G. Skopp, and G. Rippin A comparison of 3H-cocaine binding on melanin granules and human hair in vitro Int. J. Leg. Med. 110 1997 55 62
    • (1997) Int. J. Leg. Med. , vol.110 , pp. 55-62
    • Potsch, L.1    Skopp, G.2    Rippin, G.3
  • 145
    • 84876577065 scopus 로고    scopus 로고
    • NeuroGPS: Automated localization of neurons for brain circuits using L1 minimization model
    • T. Quan, T. Zheng, Z. Yang, W. Ding, S. Li, J. Li, H. Zhou, Q. Luo, H. Gong, and S. Zeng NeuroGPS: automated localization of neurons for brain circuits using L1 minimization model Sci. Rep. 3 2013 1414
    • (2013) Sci. Rep. , vol.3 , pp. 1414
    • Quan, T.1    Zheng, T.2    Yang, Z.3    Ding, W.4    Li, S.5    Li, J.6    Zhou, H.7    Luo, Q.8    Gong, H.9    Zeng, S.10
  • 146
    • 84901008067 scopus 로고    scopus 로고
    • Digital reconstruction of the cell body in dense neural circuits using a spherical-coordinated variational model
    • T. Quan, J. Li, H. Zhou, S. Li, T. Zheng, Z. Yang, Q. Luo, H. Gong, and S. Zeng Digital reconstruction of the cell body in dense neural circuits using a spherical-coordinated variational model Sci. Rep. 4 2014 4970
    • (2014) Sci. Rep. , vol.4 , pp. 4970
    • Quan, T.1    Li, J.2    Zhou, H.3    Li, S.4    Zheng, T.5    Yang, Z.6    Luo, Q.7    Gong, H.8    Zeng, S.9
  • 147
    • 84924595616 scopus 로고    scopus 로고
    • Three-dimensional reconstruction of corticospinal tract using one-photon confocal microscopy acquisition allows detection of axonal disruption in spinal cord injury
    • H.R. Quinta, L.A. Pasquini, and J.M. Pasquini Three-dimensional reconstruction of corticospinal tract using one-photon confocal microscopy acquisition allows detection of axonal disruption in spinal cord injury J. Neurochem. 133 2015 113 124
    • (2015) J. Neurochem. , vol.133 , pp. 113-124
    • Quinta, H.R.1    Pasquini, L.A.2    Pasquini, J.M.3
  • 150
    • 34548532346 scopus 로고    scopus 로고
    • Localization of a stable neural correlate of associative memory
    • L.G. Reijmers, B.L. Perkins, N. Matsuo, and M. Mayford Localization of a stable neural correlate of associative memory Science 317 2007 1230 1233
    • (2007) Science , vol.317 , pp. 1230-1233
    • Reijmers, L.G.1    Perkins, B.L.2    Matsuo, N.3    Mayford, M.4
  • 151
    • 84910092406 scopus 로고    scopus 로고
    • IDISCO: A simple, rapid method to immunolabel large tissue samples for volume imaging
    • N. Renier, Z. Wu, D.J. Simon, J. Yang, P. Ariel, and M. Tessier-Lavigne iDISCO: a simple, rapid method to immunolabel large tissue samples for volume imaging Cell 159 2014 896 910
    • (2014) Cell , vol.159 , pp. 896-910
    • Renier, N.1    Wu, Z.2    Simon, D.J.3    Yang, J.4    Ariel, P.5    Tessier-Lavigne, M.6
  • 152
    • 84937217747 scopus 로고    scopus 로고
    • Clarifying tissue clearing
    • D.S. Richardson, and J.W. Lichtman Clarifying tissue clearing Cell 162 2015 246 257
    • (2015) Cell , vol.162 , pp. 246-257
    • Richardson, D.S.1    Lichtman, J.W.2
  • 153
    • 0037332503 scopus 로고    scopus 로고
    • Nonrigid image registration in shared-memory multiprocessor environments with application to brains, breasts, and bees
    • T. Rohlfing, and C.R. Maurer Jr. Nonrigid image registration in shared-memory multiprocessor environments with application to brains, breasts, and bees IEEE Trans. Inf. Technol. Biomed. 7 2003 16 25
    • (2003) IEEE Trans. Inf. Technol. Biomed. , vol.7 , pp. 16-25
    • Rohlfing, T.1    Maurer, C.R.2
  • 155
    • 67650770056 scopus 로고    scopus 로고
    • CATMAID: Collaborative annotation toolkit for massive amounts of image data
    • S. Saalfeld, A. Cardona, V. Hartenstein, and P. Tomancak CATMAID: collaborative annotation toolkit for massive amounts of image data Bioinformatics 25 2009 1984 1986
    • (2009) Bioinformatics , vol.25 , pp. 1984-1986
    • Saalfeld, S.1    Cardona, A.2    Hartenstein, V.3    Tomancak, P.4
  • 156
    • 34147159275 scopus 로고    scopus 로고
    • Functional imaging in bulk tissue specimens using optical emission tomography: Fluorescence preservation during optical clearing
    • H.S. Sakhalkar, M. Dewhirst, T. Oliver, Y. Cao, and M. Oldham Functional imaging in bulk tissue specimens using optical emission tomography: fluorescence preservation during optical clearing Phys. Med. Biol. 52 2007 2035 2054
    • (2007) Phys. Med. Biol. , vol.52 , pp. 2035-2054
    • Sakhalkar, H.S.1    Dewhirst, M.2    Oliver, T.3    Cao, Y.4    Oldham, M.5
  • 158
    • 0026010287 scopus 로고
    • Regulation of a fos-lacZ fusion gene: A paradigm for quantitative analysis of stimulus-transcription coupling
    • K. Schilling, D. Luk, J.I. Morgan, and T. Curran Regulation of a fos-lacZ fusion gene: a paradigm for quantitative analysis of stimulus-transcription coupling Proc. Natl. Acad. Sci. USA 88 1991 5665 5669
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 5665-5669
    • Schilling, K.1    Luk, D.2    Morgan, J.I.3    Curran, T.4
  • 160
    • 84930679663 scopus 로고    scopus 로고
    • Fluorescent-protein stabilization and high-resolution imaging of cleared, intact mouse brains
    • M.K. Schwarz, A. Scherbarth, R. Sprengel, J. Engelhardt, P. Theer, and G. Giese Fluorescent-protein stabilization and high-resolution imaging of cleared, intact mouse brains PLoS One 10 2015 e0124650
    • (2015) PLoS One , vol.10
    • Schwarz, M.K.1    Scherbarth, A.2    Sprengel, R.3    Engelhardt, J.4    Theer, P.5    Giese, G.6
  • 162
    • 14744268418 scopus 로고    scopus 로고
    • Analysis of the distribution of the brain cells of the fruit fly by an automatic cell counting algorithm
    • T. Shimada, K. Kato, A. Kamikouchi, and K. Ito Analysis of the distribution of the brain cells of the fruit fly by an automatic cell counting algorithm Physica A Stat. Mech. Appl. 350 2005 144 149
    • (2005) Physica A Stat. Mech. Appl. , vol.350 , pp. 144-149
    • Shimada, T.1    Kato, K.2    Kamikouchi, A.3    Ito, K.4
  • 163
    • 84976279576 scopus 로고
    • Über Sichtbarmachung und Größenbestimmung ultramikroskopischer Teilchen, mit besonderer Anwendung auf Goldrubingläser
    • H. Siedentopf, and R. Zsigmondy Über Sichtbarmachung und Größenbestimmung ultramikroskopischer Teilchen, mit besonderer Anwendung auf Goldrubingläser Ann. Phys. 315 1903 1 39
    • (1903) Ann. Phys. , vol.315 , pp. 1-39
    • Siedentopf, H.1    Zsigmondy, R.2
  • 164
    • 0036148747 scopus 로고    scopus 로고
    • Whole-mount immunohistochemistry: A high-throughput screen for patterning defects in the mouse cerebellum
    • R.V. Sillitoe, and R. Hawkes Whole-mount immunohistochemistry: a high-throughput screen for patterning defects in the mouse cerebellum J. Histochem. Cytochem. 50 2002 235 244
    • (2002) J. Histochem. Cytochem. , vol.50 , pp. 235-244
    • Sillitoe, R.V.1    Hawkes, R.2
  • 165
    • 84865734764 scopus 로고    scopus 로고
    • Confocal light sheet microscopy: Micron-scale neuroanatomy of the entire mouse brain
    • L. Silvestri, A. Bria, L. Sacconi, G. Iannello, and F.S. Pavone Confocal light sheet microscopy: micron-scale neuroanatomy of the entire mouse brain Opt. Express 20 2012 20582 20598
    • (2012) Opt. Express , vol.20 , pp. 20582-20598
    • Silvestri, L.1    Bria, A.2    Sacconi, L.3    Iannello, G.4    Pavone, F.S.5
  • 171
    • 33846108375 scopus 로고    scopus 로고
    • 2,2'-Thiodiethanol: A new water soluble mounting medium for high resolution optical microscopy
    • T. Staudt, M.C. Lang, R. Medda, J. Engelhardt, and S.W. Hell 2,2'-Thiodiethanol: a new water soluble mounting medium for high resolution optical microscopy Microsc. Res. Tech. 70 2007 1 9
    • (2007) Microsc. Res. Tech. , vol.70 , pp. 1-9
    • Staudt, T.1    Lang, M.C.2    Medda, R.3    Engelhardt, J.4    Hell, S.W.5
  • 172
    • 0001398396 scopus 로고
    • Comparison of Mie theory and the light scattering of red blood cells
    • J.M. Steinke, and A.P. Shepherd Comparison of Mie theory and the light scattering of red blood cells Appl. Opt. 27 1988 4027 4033
    • (1988) Appl. Opt. , vol.27 , pp. 4027-4033
    • Steinke, J.M.1    Shepherd, A.P.2
  • 173
    • 0035132802 scopus 로고    scopus 로고
    • A modified Spalteholz technique with preservation of the histology
    • H. Steinke, and W. Wolff A modified Spalteholz technique with preservation of the histology Ann. Anat. 183 2001 91 95
    • (2001) Ann. Anat. , vol.183 , pp. 91-95
    • Steinke, H.1    Wolff, W.2
  • 175
    • 84944397824 scopus 로고    scopus 로고
    • Advanced CUBIC protocols for whole-brain and whole-body clearing and imaging
    • E.A. Susaki, K. Tainaka, D. Perrin, H. Yukinaga, A. Kuno, and H.R. Ueda Advanced CUBIC protocols for whole-brain and whole-body clearing and imaging Nat. Protoc. 10 2015 1709 1727
    • (2015) Nat. Protoc. , vol.10 , pp. 1709-1727
    • Susaki, E.A.1    Tainaka, K.2    Perrin, D.3    Yukinaga, H.4    Kuno, A.5    Ueda, H.R.6
  • 177
    • 84863195203 scopus 로고    scopus 로고
    • Quantitative high-speed imaging of entire developing embryos with simultaneous multiview light-sheet microscopy
    • R. Tomer, K. Khairy, F. Amat, and P.J. Keller Quantitative high-speed imaging of entire developing embryos with simultaneous multiview light-sheet microscopy Nat. Methods 9 2012 755 763
    • (2012) Nat. Methods , vol.9 , pp. 755-763
    • Tomer, R.1    Khairy, K.2    Amat, F.3    Keller, P.J.4
  • 178
    • 84964313635 scopus 로고    scopus 로고
    • Advanced CLARITY for rapid and high-resolution imaging of intact tissues
    • R. Tomer, L. Ye, B. Hsueh, and K. Deisseroth Advanced CLARITY for rapid and high-resolution imaging of intact tissues Nat. Protoc. 9 2014 1682 1697
    • (2014) Nat. Protoc. , vol.9 , pp. 1682-1697
    • Tomer, R.1    Ye, L.2    Hsueh, B.3    Deisseroth, K.4
  • 179
    • 84965191403 scopus 로고    scopus 로고
    • Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high-resolution intact circuit mapping and phenotyping
    • J.B. Treweek, K.Y. Chan, N.C. Flytzanis, B. Yang, B.E. Deverman, A. Greenbaum, A. Lignell, C. Xiao, L. Cai, M.S. Ladinsky, and et al. Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high-resolution intact circuit mapping and phenotyping Nat. Protoc. 10 2015 1860 1896
    • (2015) Nat. Protoc. , vol.10 , pp. 1860-1896
    • Treweek, J.B.1    Chan, K.Y.2    Flytzanis, N.C.3    Yang, B.4    Deverman, B.E.5    Greenbaum, A.6    Lignell, A.7    Xiao, C.8    Cai, L.9    Ladinsky, M.S.10
  • 180
    • 80052298394 scopus 로고    scopus 로고
    • Deep and fast live imaging with two-photon scanned light-sheet microscopy
    • T.V. Truong, W. Supatto, D.S. Koos, J.M. Choi, and S.E. Fraser Deep and fast live imaging with two-photon scanned light-sheet microscopy Nat. Methods 8 2011 757 760
    • (2011) Nat. Methods , vol.8 , pp. 757-760
    • Truong, T.V.1    Supatto, W.2    Koos, D.S.3    Choi, J.M.4    Fraser, S.E.5
  • 181
    • 70949083465 scopus 로고    scopus 로고
    • Correlations of neuronal and microvascular densities in murine cortex revealed by direct counting and colocalization of nuclei and vessels
    • P.S. Tsai, J.P. Kaufhold, P. Blinder, B. Friedman, P.J. Drew, H.J. Karten, P.D. Lyden, and D. Kleinfeld Correlations of neuronal and microvascular densities in murine cortex revealed by direct counting and colocalization of nuclei and vessels J. Neurosci. 29 2009 14553 14570
    • (2009) J. Neurosci. , vol.29 , pp. 14553-14570
    • Tsai, P.S.1    Kaufhold, J.P.2    Blinder, P.3    Friedman, B.4    Drew, P.J.5    Karten, H.J.6    Lyden, P.D.7    Kleinfeld, D.8
  • 182
    • 84965007707 scopus 로고    scopus 로고
    • Tissue optics and photonics: Light-tissue interaction
    • V.V. Tuchin Tissue optics and photonics: light-tissue interaction J. Biomed. Photon. Eng. 1 2015 98 134
    • (2015) J. Biomed. Photon. Eng. , vol.1 , pp. 98-134
    • Tuchin, V.V.1
  • 184
    • 77954729598 scopus 로고    scopus 로고
    • Image-based calibration of a deformable mirror in wide-field microscopy
    • D. Turaga, and T.E. Holy Image-based calibration of a deformable mirror in wide-field microscopy Appl. Opt. 49 2010 2030 2040
    • (2010) Appl. Opt. , vol.49 , pp. 2030-2040
    • Turaga, D.1    Holy, T.E.2
  • 185
    • 84943311622 scopus 로고    scopus 로고
    • Super-resolution stimulated emission depletion imaging of slit diaphragm proteins in optically cleared kidney tissue
    • D. Unnersjö-Jess, L. Scott, H. Blom, and H. Brismar Super-resolution stimulated emission depletion imaging of slit diaphragm proteins in optically cleared kidney tissue Kidney Int. 2015 10.1038/ki.2015.308
    • (2015) Kidney Int.
    • Unnersjö-Jess, D.1    Scott, L.2    Blom, H.3    Brismar, H.4
  • 188
    • 0034789744 scopus 로고    scopus 로고
    • Use of osmotically active agents to alter optical properties of tissue: Effects on the detected fluorescence signal measured through skin
    • G. Vargas, K.F. Chan, S.L. Thomsen, and A.J. Welch Use of osmotically active agents to alter optical properties of tissue: effects on the detected fluorescence signal measured through skin Lasers Surg. Med. 29 2001 213 220
    • (2001) Lasers Surg. Med. , vol.29 , pp. 213-220
    • Vargas, G.1    Chan, K.F.2    Thomsen, S.L.3    Welch, A.J.4
  • 189
    • 84922018753 scopus 로고    scopus 로고
    • The stimulus selectivity and connectivity of layer six principal cells reveals cortical microcircuits underlying visual processing
    • M. Velez-Fort, C.V. Rousseau, C.J. Niedworok, I.R. Wickersham, E.A. Rancz, A.P. Brown, M. Strom, and T.W. Margrie The stimulus selectivity and connectivity of layer six principal cells reveals cortical microcircuits underlying visual processing Neuron 83 2014 1431 1443
    • (2014) Neuron , vol.83 , pp. 1431-1443
    • Velez-Fort, M.1    Rousseau, C.V.2    Niedworok, C.J.3    Wickersham, I.R.4    Rancz, E.A.5    Brown, A.P.6    Strom, M.7    Margrie, T.W.8
  • 192
    • 0027270794 scopus 로고
    • Orthogonal-plane fluorescence optical sectioning: Three-dimensional imaging of macroscopic biological specimens
    • A.H. Voie, D.H. Burns, and F.A. Spelman Orthogonal-plane fluorescence optical sectioning: three-dimensional imaging of macroscopic biological specimens J. Microsc. 170 1993 229 236
    • (1993) J. Microsc. , vol.170 , pp. 229-236
    • Voie, A.H.1    Burns, D.H.2    Spelman, F.A.3
  • 195
    • 51349110512 scopus 로고    scopus 로고
    • Three-dimensional analysis of vascular development in the mouse embryo
    • J.R. Walls, L. Coultas, J. Rossant, and R.M. Henkelman Three-dimensional analysis of vascular development in the mouse embryo PLoS One 3 2008 e2853
    • (2008) PLoS One , vol.3
    • Walls, J.R.1    Coultas, L.2    Rossant, J.3    Henkelman, R.M.4
  • 196
    • 33746228125 scopus 로고    scopus 로고
    • In vivo two-photon imaging reveals a role of Arc in enhancing orientation specificity in visual cortex
    • K.H. Wang, A. Majewska, J. Schummers, B. Farley, C.C. Hu, M. Sur, and S. Tonegawa In vivo two-photon imaging reveals a role of Arc in enhancing orientation specificity in visual cortex Cell 126 2006 389 402
    • (2006) Cell , vol.126 , pp. 389-402
    • Wang, K.H.1    Majewska, A.2    Schummers, J.3    Farley, B.4    Hu, C.C.5    Sur, M.6    Tonegawa, S.7
  • 197
    • 0035318612 scopus 로고    scopus 로고
    • A clearer vision for in vivo imaging
    • R. Weissleder A clearer vision for in vivo imaging Nat. Biotechnol. 19 2001 316 317
    • (2001) Nat. Biotechnol. , vol.19 , pp. 316-317
    • Weissleder, R.1
  • 198
    • 72149099602 scopus 로고    scopus 로고
    • Controling the scattering of intralipid by using optical clearing agents
    • X. Wen, V.V. Tuchin, Q.M. Luo, and D. Zhu Controling the scattering of intralipid by using optical clearing agents Phys. Med. Biol. 54 2009 6917 6930
    • (2009) Phys. Med. Biol. , vol.54 , pp. 6917-6930
    • Wen, X.1    Tuchin, V.V.2    Luo, Q.M.3    Zhu, D.4
  • 201
    • 0025541528 scopus 로고
    • Optical reflectance and transmittance of tissues: Principles and applications
    • B.C.J. Wilson, and L. Steven Optical reflectance and transmittance of tissues: principles and applications Quant. Electro. IEEE J. 26 1990 2186 2199
    • (1990) Quant. Electro. IEEE J. , vol.26 , pp. 2186-2199
    • Wilson, B.C.J.1    Steven, L.2
  • 202
    • 84883426931 scopus 로고    scopus 로고
    • Design and implementation of a custom built optical projection tomography system
    • M.D. Wong, J. Dazai, J.R. Walls, N.W. Gale, and R.M. Henkelman Design and implementation of a custom built optical projection tomography system PLoS One 8 2013 e73491
    • (2013) PLoS One , vol.8
    • Wong, M.D.1    Dazai, J.2    Walls, J.R.3    Gale, N.W.4    Henkelman, R.M.5
  • 203
    • 80055070317 scopus 로고    scopus 로고
    • Inverted selective plane illumination microscopy (iSPIM) enables coupled cell identity lineaging and neurodevelopmental imaging in Caenorhabditis elegans
    • Y.C. Wu, A. Ghitani, R. Christensen, A. Santella, Z. Du, G. Rondeau, Z.R. Bao, D. Colon-Ramos, and H. Shroff Inverted selective plane illumination microscopy (iSPIM) enables coupled cell identity lineaging and neurodevelopmental imaging in Caenorhabditis elegans Proc. Natl. Acad. Sci. USA 108 2011 17708 17713
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 17708-17713
    • Wu, Y.C.1    Ghitani, A.2    Christensen, R.3    Santella, A.4    Du, Z.5    Rondeau, G.6    Bao, Z.R.7    Colon-Ramos, D.8    Shroff, H.9
  • 205
    • 84890953471 scopus 로고    scopus 로고
    • 3D BrainCV: Simultaneous visualization and analysis of cells and capillaries in a whole mouse brain with one-micron voxel resolution
    • J.P. Wu, Y. He, Z.Q. Yang, C.D. Guo, Q.M. Luo, W. Zhou, S.B. Chen, A.A. Li, B.Y. Xiong, T. Jiang, and et al. 3D BrainCV: simultaneous visualization and analysis of cells and capillaries in a whole mouse brain with one-micron voxel resolution Neuroimage 87 2014 199 208
    • (2014) Neuroimage , vol.87 , pp. 199-208
    • Wu, J.P.1    He, Y.2    Yang, Z.Q.3    Guo, C.D.4    Luo, Q.M.5    Zhou, W.6    Chen, S.B.7    Li, A.A.8    Xiong, B.Y.9    Jiang, T.10
  • 206
    • 84884289608 scopus 로고    scopus 로고
    • One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering
    • H. Yang, H.Y. Wang, C.S. Shivalila, A.W. Cheng, L.Y. Shi, and R. Jaenisch One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering Cell 154 2013 1370 1379
    • (2013) Cell , vol.154 , pp. 1370-1379
    • Yang, H.1    Wang, H.Y.2    Shivalila, C.S.3    Cheng, A.W.4    Shi, L.Y.5    Jaenisch, R.6
  • 208
    • 33744469104 scopus 로고    scopus 로고
    • Molecular interactions of exogenous chemical agents with collagen - Implications for tissue optical clearing
    • A.T. Yeh, and J. Hirshburg Molecular interactions of exogenous chemical agents with collagen - implications for tissue optical clearing J. Biomed. Opt. 11 2006 014003
    • (2006) J. Biomed. Opt. , vol.11
    • Yeh, A.T.1    Hirshburg, J.2
  • 210
    • 80052542897 scopus 로고    scopus 로고
    • Quantitative analysis of dehydration in porcine skin for assessing mechanism of optical clearing
    • T.T. Yu, X. Wen, V.V. Tuchin, Q.M. Luo, and D. Zhu Quantitative analysis of dehydration in porcine skin for assessing mechanism of optical clearing J. Biomed. Opt. 16 2011 095002
    • (2011) J. Biomed. Opt. , vol.16
    • Yu, T.T.1    Wen, X.2    Tuchin, V.V.3    Luo, Q.M.4    Zhu, D.5
  • 211
    • 33744930583 scopus 로고    scopus 로고
    • User-guided 3D active contour segmentation of anatomical structures: Significantly improved efficiency and reliability
    • P.A. Yushkevich, J. Piven, H.C. Hazlett, R.G. Smith, S. Ho, J.C. Gee, and G. Gerig User-guided 3D active contour segmentation of anatomical structures: significantly improved efficiency and reliability Neuroimage 31 2006 1116 1128
    • (2006) Neuroimage , vol.31 , pp. 1116-1128
    • Yushkevich, P.A.1    Piven, J.2    Hazlett, H.C.3    Smith, R.G.4    Ho, S.5    Gee, J.C.6    Gerig, G.7
  • 213
    • 79953044014 scopus 로고    scopus 로고
    • Modified Golgi-Cox method for micrometer scale sectioning of the whole mouse brain
    • B. Zhang, A. Li, Z. Yang, J. Wu, Q. Luo, and H. Gong Modified Golgi-Cox method for micrometer scale sectioning of the whole mouse brain J. Neurosci. Methods 197 2011 1 5
    • (2011) J. Neurosci. Methods , vol.197 , pp. 1-5
    • Zhang, B.1    Li, A.2    Yang, Z.3    Wu, J.4    Luo, Q.5    Gong, H.6
  • 216
    • 65249126962 scopus 로고    scopus 로고
    • Following dimethyl sulfoxide skin optical clearing dynamics with quantitative nonlinear multimodal microscopy
    • M. Zimmerley, R.A. McClure, B. Choi, and E.O. Potma Following dimethyl sulfoxide skin optical clearing dynamics with quantitative nonlinear multimodal microscopy Appl. Opt. 48 2009 D79 D87
    • (2009) Appl. Opt. , vol.48 , pp. D79-D87
    • Zimmerley, M.1    McClure, R.A.2    Choi, B.3    Potma, E.O.4


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