Synaptic activity-responsive element in the Arc/Arg3.1 promoter essential for synapse-to-nucleus signaling in activated neurons

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 1, 2009, Pages 316-321

  Kawashima, Takashi ^a   Okuno, Hiroyuki ^a   Nonaka, Mio ^a   Adachi Morishima, Aki ^a   Kyo, Nan ^a   Okamura, Michiko ^a   Takemoto Kimura, Sayaka ^a   Worley, Paul F ^b   Bito, Haruhiko ^a,c  

^a UNIVERSITY OF TOKYO   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Calcium; CREB; Immediate early genes; MEF2; SRF

Indexed keywords

CIS ACTING ELEMENT; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; LUCIFERASE; MOLECULAR MARKER; PROTEIN; PROTEIN MEF2; PROTEIN SRF; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARC/ARG3.1 GENE; ARTICLE; BINDING SITE; BRAIN CELL; BRAIN CORTEX; CELL ACTIVATION; CELL ACTIVITY; CELL NUCLEUS; CONTROLLED STUDY; EMBRYO; ENZYME ASSAY; GENE; GENE ACTIVITY; GENE EXPRESSION; GENE IDENTIFICATION; GENE LOCATION; GENE MAPPING; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RAT; SIGNAL TRANSDUCTION; SYNAPSE; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION REGULATION;

ANIMALS; BINDING SITES; CELL NUCLEUS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYTOSKELETAL PROTEINS; GENE EXPRESSION REGULATION; GENOMICS; MICE; MYOGENIC REGULATORY FACTORS; NERVE TISSUE PROTEINS; NEURONS; PROMOTER REGIONS, GENETIC; REGULATORY SEQUENCES, NUCLEIC ACID; SERUM RESPONSE FACTOR; SIGNAL TRANSDUCTION; SYNAPSES;

EID: 58549092132     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0806518106     Document Type: Article

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