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Volumn 17, Issue S1, 2015, Pages 47-54

Seeing the forest and trees: Whole-body and whole-brain imaging for circadian biology

Author keywords

Light sheet microscope; Single cell resolution; Tissue clearing

Indexed keywords

HEMOGLOBIN; LIPID;

EID: 84940551571     PISSN: 14628902     EISSN: 14631326     Source Type: Journal    
DOI: 10.1111/dom.12511     Document Type: Review
Times cited : (5)

References (58)
  • 1
    • 78649687209 scopus 로고    scopus 로고
    • Circadian integration of metabolism and energetics
    • Bass J, Takahashi JS. Circadian integration of metabolism and energetics. Science 2010; 330: 1349-1354.
    • (2010) Science , vol.330 , pp. 1349-1354
    • Bass, J.1    Takahashi, J.S.2
  • 2
    • 0015353260 scopus 로고
    • Circadian rhythms in drinking behavior and locomotor activity of rats are eliminated by hypothalamic lesions
    • Stephan FK, Zucker I. Circadian rhythms in drinking behavior and locomotor activity of rats are eliminated by hypothalamic lesions. Proc Natl Acad Sci U S A 1972; 69: 1583-1586.
    • (1972) Proc Natl Acad Sci U S A , vol.69 , pp. 1583-1586
    • Stephan, F.K.1    Zucker, I.2
  • 3
    • 0015504847 scopus 로고
    • Loss of a circadian adrenal corticosterone rhythm following suprachiasmatic lesions in the rat
    • Moore RY, Eichler VB. Loss of a circadian adrenal corticosterone rhythm following suprachiasmatic lesions in the rat. Brain Res 1972; 42: 201-206.
    • (1972) Brain Res , vol.42 , pp. 201-206
    • Moore, R.Y.1    Eichler, V.B.2
  • 4
    • 0025021084 scopus 로고
    • Transplanted suprachiasmatic nucleus determines circadian period
    • Ralph MR, Foster RG, Davis FC, Menaker M. Transplanted suprachiasmatic nucleus determines circadian period. Science 1990; 247: 975-978.
    • (1990) Science , vol.247 , pp. 975-978
    • Ralph, M.R.1    Foster, R.G.2    Davis, F.C.3    Menaker, M.4
  • 5
    • 0020465202 scopus 로고
    • Circadian rhythms in electrical discharge of rat suprachiasmatic neurones recorded in vitro
    • Groos G, Hendriks J. Circadian rhythms in electrical discharge of rat suprachiasmatic neurones recorded in vitro. Neurosci Lett 1982; 34: 283-288.
    • (1982) Neurosci Lett , vol.34 , pp. 283-288
    • Groos, G.1    Hendriks, J.2
  • 6
    • 0020029696 scopus 로고
    • Circadian rhythm of firing rate recorded from single cells in the rat suprachiasmatic brain slice
    • Green DJ, Gillette R. Circadian rhythm of firing rate recorded from single cells in the rat suprachiasmatic brain slice. Brain Res 1982; 245: 198-200.
    • (1982) Brain Res , vol.245 , pp. 198-200
    • Green, D.J.1    Gillette, R.2
  • 7
    • 0028904194 scopus 로고
    • Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms
    • Welsh DK, Logothetis DE, Meister M, Reppert SM. Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms. Neuron 1995; 14: 697-706.
    • (1995) Neuron , vol.14 , pp. 697-706
    • Welsh, D.K.1    Logothetis, D.E.2    Meister, M.3    Reppert, S.M.4
  • 8
    • 0021680955 scopus 로고
    • Molecular analysis of the period locus in Drosophila melanogaster and identification of a transcript involved in biological rhythms
    • Reddy P, Zehring WA, Wheeler DA et al. Molecular analysis of the period locus in Drosophila melanogaster and identification of a transcript involved in biological rhythms. Cell 1984; 38: 701-710.
    • (1984) Cell , vol.38 , pp. 701-710
    • Reddy, P.1    Zehring, W.A.2    Wheeler, D.A.3
  • 9
    • 0015119210 scopus 로고
    • Clock mutants of Drosophila melanogaster
    • Konopka RJ, Benzer S. Clock mutants of Drosophila melanogaster. Proc Natl Acad Sci U S A 1971; 68: 2112-2116.
    • (1971) Proc Natl Acad Sci U S A , vol.68 , pp. 2112-2116
    • Konopka, R.J.1    Benzer, S.2
  • 10
    • 0028241271 scopus 로고
    • Mutagenesis and mapping of a mouse gene, Clock, essential for circadian behavior
    • Vitaterna MH, King DP, Chang AM et al. Mutagenesis and mapping of a mouse gene, Clock, essential for circadian behavior. Science 1994; 264: 719-725.
    • (1994) Science , vol.264 , pp. 719-725
    • Vitaterna, M.H.1    King, D.P.2    Chang, A.M.3
  • 11
    • 77951897767 scopus 로고    scopus 로고
    • Systems biology of mammalian circadian clocks
    • Ukai H, Ueda HR. Systems biology of mammalian circadian clocks. Annu Rev Physiol 2010; 72: 579-603.
    • (2010) Annu Rev Physiol , vol.72 , pp. 579-603
    • Ukai, H.1    Ueda, H.R.2
  • 12
    • 0034724728 scopus 로고    scopus 로고
    • Resetting central and peripheral circadian oscillators in transgenic rats
    • Yamazaki S, Numano R, Abe M et al. Resetting central and peripheral circadian oscillators in transgenic rats. Science 2000; 288: 682-685.
    • (2000) Science , vol.288 , pp. 682-685
    • Yamazaki, S.1    Numano, R.2    Abe, M.3
  • 13
    • 0032511229 scopus 로고    scopus 로고
    • A serum shock induces circadian gene expression in mammalian tissue culture cells
    • Balsalobre A, Damiola F, Schibler U. A serum shock induces circadian gene expression in mammalian tissue culture cells. Cell 1998; 93: 929-937.
    • (1998) Cell , vol.93 , pp. 929-937
    • Balsalobre, A.1    Damiola, F.2    Schibler, U.3
  • 14
    • 0042566193 scopus 로고    scopus 로고
    • Temperature compensation and temperature resetting of circadian rhythms in mammalian cultured fibroblasts
    • Tsuchiya Y, Akashi M, Nishida E. Temperature compensation and temperature resetting of circadian rhythms in mammalian cultured fibroblasts. Genes Cells 2003; 8: 713-720.
    • (2003) Genes Cells , vol.8 , pp. 713-720
    • Tsuchiya, Y.1    Akashi, M.2    Nishida, E.3
  • 15
    • 55149112074 scopus 로고    scopus 로고
    • A high-throughput assay for siRNA-based circadian screens in human U2OS cells
    • Vollmers C, Panda S, DiTacchio L. A high-throughput assay for siRNA-based circadian screens in human U2OS cells. PLoS One 2008; 3: e3457.
    • (2008) PLoS One , vol.3 , pp. e3457
    • Vollmers, C.1    Panda, S.2    DiTacchio, L.3
  • 16
    • 11144353910 scopus 로고    scopus 로고
    • PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues
    • Yoo SH, Yamazaki S, Lowrey PL et al. PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues. Proc Natl Acad Sci U S A 2004; 101: 5339-5346.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 5339-5346
    • Yoo, S.H.1    Yamazaki, S.2    Lowrey, P.L.3
  • 17
    • 34247899223 scopus 로고    scopus 로고
    • Ultramicroscopy: three-dimensional visualization of neuronal networks in the whole mouse brain
    • Dodt HU, Leischner U, Schierloh A et al. Ultramicroscopy: three-dimensional visualization of neuronal networks in the whole mouse brain. Nat Methods 2007; 4: 331-336.
    • (2007) Nat Methods , vol.4 , pp. 331-336
    • Dodt, H.U.1    Leischner, U.2    Schierloh, A.3
  • 18
    • 84859132261 scopus 로고    scopus 로고
    • Chemical clearing and dehydration of GFP expressing mouse brains
    • Becker K, Jahrling N, Saghafi S, Weiler R, Dodt HU. Chemical clearing and dehydration of GFP expressing mouse brains. PLoS One 2012; 7: e33916.
    • (2012) PLoS One , vol.7 , pp. e33916
    • Becker, K.1    Jahrling, N.2    Saghafi, S.3    Weiler, R.4    Dodt, H.U.5
  • 19
    • 84868135888 scopus 로고    scopus 로고
    • Three-dimensional imaging of solvent-cleared organs using 3DISCO
    • Erturk A, Becker K, Jahrling N et al. Three-dimensional imaging of solvent-cleared organs using 3DISCO. Nat Protoc 2012; 7: 1983-1995.
    • (2012) Nat Protoc , vol.7 , pp. 1983-1995
    • Erturk, A.1    Becker, K.2    Jahrling, N.3
  • 20
    • 84910092406 scopus 로고    scopus 로고
    • iDISCO: a simple, rapid method to immunolabel large tissue samples for volume imaging
    • Renier N, Wu Z, Simon DJ, Yang J, Ariel P, Tessier-Lavigne M. iDISCO: a simple, rapid method to immunolabel large tissue samples for volume imaging. Cell 2014; 159: 896-910.
    • (2014) Cell , vol.159 , pp. 896-910
    • Renier, N.1    Wu, Z.2    Simon, D.J.3    Yang, J.4    Ariel, P.5    Tessier-Lavigne, M.6
  • 21
    • 80054995024 scopus 로고    scopus 로고
    • Scale: a chemical approach for fluorescence imaging and reconstruction of transparent mouse brain
    • Hama H, Kurokawa H, Kawano H et al. Scale: a chemical approach for fluorescence imaging and reconstruction of transparent mouse brain. Nat Neurosci 2011; 14: 1481-1488.
    • (2011) Nat Neurosci , vol.14 , pp. 1481-1488
    • Hama, H.1    Kurokawa, H.2    Kawano, H.3
  • 22
    • 84880920117 scopus 로고    scopus 로고
    • SeeDB: a simple and morphology-preserving optical clearing agent for neuronal circuit reconstruction
    • Ke MT, Fujimoto S, Imai T. SeeDB: a simple and morphology-preserving optical clearing agent for neuronal circuit reconstruction. Nat Neurosci 2013; 16: 1154-1161.
    • (2013) Nat Neurosci , vol.16 , pp. 1154-1161
    • Ke, M.T.1    Fujimoto, S.2    Imai, T.3
  • 23
    • 84899620303 scopus 로고    scopus 로고
    • Whole-brain imaging with single-cell resolution using chemical cocktails and computational analysis
    • Susaki EA, Tainaka K, Perrin D et al. Whole-brain imaging with single-cell resolution using chemical cocktails and computational analysis. Cell 2014; 157: 726-739.
    • (2014) Cell , vol.157 , pp. 726-739
    • Susaki, E.A.1    Tainaka, K.2    Perrin, D.3
  • 24
    • 84874536260 scopus 로고    scopus 로고
    • ClearT: a detergent- and solvent-free clearing method for neuronal and non-neuronal tissue
    • Kuwajima T, Sitko AA, Bhansali P, Jurgens C, Guido W, Mason C. ClearT: a detergent- and solvent-free clearing method for neuronal and non-neuronal tissue. Development 2013; 140: 1364-1368.
    • (2013) Development , vol.140 , pp. 1364-1368
    • Kuwajima, T.1    Sitko, A.A.2    Bhansali, P.3    Jurgens, C.4    Guido, W.5    Mason, C.6
  • 25
    • 84961288329 scopus 로고    scopus 로고
    • A rapid optical clearing protocol using 2,2'-thiodiethanol for microscopic observation of fixed mouse brain
    • Aoyagi Y, Kawakami R, Osanai H, Hibi T, Nemoto T. A rapid optical clearing protocol using 2, 2'-thiodiethanol for microscopic observation of fixed mouse brain. PLoS One 2015; 10: e0116280.
    • (2015) PLoS One , vol.10 , pp. e0116280
    • Aoyagi, Y.1    Kawakami, R.2    Osanai, H.3    Hibi, T.4    Nemoto, T.5
  • 26
    • 84878115127 scopus 로고    scopus 로고
    • Structural and molecular interrogation of intact biological systems
    • Chung K, Wallace J, Kim SY et al. Structural and molecular interrogation of intact biological systems. Nature 2013; 497: 332-337.
    • (2013) Nature , vol.497 , pp. 332-337
    • Chung, K.1    Wallace, J.2    Kim, S.Y.3
  • 27
    • 84964313635 scopus 로고    scopus 로고
    • Advanced CLARITY for rapid and high-resolution imaging of intact tissues
    • Tomer R, Ye L, Hsueh B, Deisseroth K. Advanced CLARITY for rapid and high-resolution imaging of intact tissues. Nat Protoc 2014; 9: 1682-1697.
    • (2014) Nat Protoc , vol.9 , pp. 1682-1697
    • Tomer, R.1    Ye, L.2    Hsueh, B.3    Deisseroth, K.4
  • 28
    • 84908404143 scopus 로고    scopus 로고
    • Single-cell phenotyping within transparent intact tissue through whole-body clearing
    • Yang B, Treweek JB, Kulkarni RP et al. Single-cell phenotyping within transparent intact tissue through whole-body clearing. Cell 2014; 158: 945-958.
    • (2014) Cell , vol.158 , pp. 945-958
    • Yang, B.1    Treweek, J.B.2    Kulkarni, R.P.3
  • 29
    • 84910025752 scopus 로고    scopus 로고
    • Whole-body imaging with single-cell resolution by tissue decolorization
    • Tainaka K, Kubota SI, Suyama TQ et al. Whole-body imaging with single-cell resolution by tissue decolorization. Cell 2014; 159: 911-924.
    • (2014) Cell , vol.159 , pp. 911-924
    • Tainaka, K.1    Kubota, S.I.2    Suyama, T.Q.3
  • 30
    • 84922021732 scopus 로고    scopus 로고
    • Visualizing whole-brain activity and development at the single-cell level using light-sheet microscopy
    • Keller PJ, Ahrens MB. Visualizing whole-brain activity and development at the single-cell level using light-sheet microscopy. Neuron 2015; 85: 462-483.
    • (2015) Neuron , vol.85 , pp. 462-483
    • Keller, P.J.1    Ahrens, M.B.2
  • 31
    • 0029781519 scopus 로고    scopus 로고
    • A diffusible coupling signal from the transplanted suprachiasmatic nucleus controlling circadian locomotor rhythms
    • Silver R, LeSauter J, Tresco PA, Lehman MN. A diffusible coupling signal from the transplanted suprachiasmatic nucleus controlling circadian locomotor rhythms. Nature 1996; 382: 810-813.
    • (1996) Nature , vol.382 , pp. 810-813
    • Silver, R.1    LeSauter, J.2    Tresco, P.A.3    Lehman, M.N.4
  • 32
    • 84875379260 scopus 로고    scopus 로고
    • Neuroanatomy of the extended circadian rhythm system
    • Morin LP. Neuroanatomy of the extended circadian rhythm system. Exp Neurol 2013; 243: 4-20.
    • (2013) Exp Neurol , vol.243 , pp. 4-20
    • Morin, L.P.1
  • 33
    • 84892679362 scopus 로고    scopus 로고
    • Dual regulation of clock gene Per2 expression in discrete brain areas by the circadian pacemaker and methamphetamine-induced oscillator in rats
    • Natsubori A, Honma K, Honma S. Dual regulation of clock gene Per2 expression in discrete brain areas by the circadian pacemaker and methamphetamine-induced oscillator in rats. Eur J Neurosci 2014; 39: 229-240.
    • (2014) Eur J Neurosci , vol.39 , pp. 229-240
    • Natsubori, A.1    Honma, K.2    Honma, S.3
  • 34
    • 0035057450 scopus 로고    scopus 로고
    • Restricted-feeding-induced anticipatory activity rhythm is associated with a phase-shift of the expression of mPer1 and mPer2 mRNA in the cerebral cortex and hippocampus but not in the suprachiasmatic nucleus of mice
    • Wakamatsu H, Yoshinobu Y, Aida R, Moriya T, Akiyama M, Shibata S. Restricted-feeding-induced anticipatory activity rhythm is associated with a phase-shift of the expression of mPer1 and mPer2 mRNA in the cerebral cortex and hippocampus but not in the suprachiasmatic nucleus of mice. Eur J Neurosci 2001; 13: 1190-1196.
    • (2001) Eur J Neurosci , vol.13 , pp. 1190-1196
    • Wakamatsu, H.1    Yoshinobu, Y.2    Aida, R.3    Moriya, T.4    Akiyama, M.5    Shibata, S.6
  • 35
    • 84930247091 scopus 로고    scopus 로고
    • Clock genes control cortical critical period timing
    • Kobayashi Y, Ye Z, Hensch TK. Clock genes control cortical critical period timing. Neuron 2015; 86: 264-275.
    • (2015) Neuron , vol.86 , pp. 264-275
    • Kobayashi, Y.1    Ye, Z.2    Hensch, T.K.3
  • 36
    • 3843091540 scopus 로고    scopus 로고
    • Molecular-timetable methods for detection of body time and rhythm disorders from single-time-point genome-wide expression profiles
    • Ueda HR, Chen W, Minami Y et al. Molecular-timetable methods for detection of body time and rhythm disorders from single-time-point genome-wide expression profiles. Proc Natl Acad Sci U S A 2004; 101: 11227-11232.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 11227-11232
    • Ueda, H.R.1    Chen, W.2    Minami, Y.3
  • 37
    • 67649875655 scopus 로고    scopus 로고
    • Measurement of internal body time by blood metabolomics
    • Minami Y, Kasukawa T, Kakazu Y et al. Measurement of internal body time by blood metabolomics. Proc Natl Acad Sci U S A 2009; 106: 9890-9895.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 9890-9895
    • Minami, Y.1    Kasukawa, T.2    Kakazu, Y.3
  • 38
    • 84871917034 scopus 로고    scopus 로고
    • Human blood metabolite timetable indicates internal body time
    • Kasukawa T, Sugimoto M, Hida A et al. Human blood metabolite timetable indicates internal body time. Proc Natl Acad Sci U S A 2012; 109: 15036-15041.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 15036-15041
    • Kasukawa, T.1    Sugimoto, M.2    Hida, A.3
  • 39
    • 84885623978 scopus 로고    scopus 로고
    • Mice genetically deficient in vasopressin V1a and V1b receptors are resistant to jet lag
    • Yamaguchi Y, Suzuki T, Mizoro Y et al. Mice genetically deficient in vasopressin V1a and V1b receptors are resistant to jet lag. Science 2013; 342: 85-90.
    • (2013) Science , vol.342 , pp. 85-90
    • Yamaguchi, Y.1    Suzuki, T.2    Mizoro, Y.3
  • 40
    • 84887481024 scopus 로고    scopus 로고
    • A neuropeptide speeds circadian entrainment by reducing intercellular synchrony
    • An S, Harang R, Meeker K et al. A neuropeptide speeds circadian entrainment by reducing intercellular synchrony. Proc Natl Acad Sci U S A 2013; 110: E4355-E4361.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. E4355-E4361
    • An, S.1    Harang, R.2    Meeker, K.3
  • 41
    • 84924257556 scopus 로고    scopus 로고
    • Neuromedin s-producing neurons act as essential pacemakers in the suprachiasmatic nucleus to couple clock neurons and dictate circadian rhythms
    • Lee IT, Chang AS, Manandhar M et al. Neuromedin s-producing neurons act as essential pacemakers in the suprachiasmatic nucleus to couple clock neurons and dictate circadian rhythms. Neuron 2015; 85: 1086-1102.
    • (2015) Neuron , vol.85 , pp. 1086-1102
    • Lee, I.T.1    Chang, A.S.2    Manandhar, M.3
  • 42
    • 13444303901 scopus 로고    scopus 로고
    • Identification of neuromedin S and its possible role in the mammalian circadian oscillator system
    • Mori K, Miyazato M, Ida T et al. Identification of neuromedin S and its possible role in the mammalian circadian oscillator system. EMBO J 2005; 24: 325-335.
    • (2005) EMBO J , vol.24 , pp. 325-335
    • Mori, K.1    Miyazato, M.2    Ida, T.3
  • 43
    • 84899141774 scopus 로고    scopus 로고
    • A new era for functional labeling of neurons: activity-dependent promoters have come of age
    • Kawashima T, Okuno H, Bito H. A new era for functional labeling of neurons: activity-dependent promoters have come of age. Front Neural Circuits 2014; 8: 37.
    • (2014) Front Neural Circuits , vol.8 , pp. 37
    • Kawashima, T.1    Okuno, H.2    Bito, H.3
  • 44
    • 58549112040 scopus 로고    scopus 로고
    • Astrocytic modulation of sleep homeostasis and cognitive consequences of sleep loss
    • Halassa MM, Florian C, Fellin T et al. Astrocytic modulation of sleep homeostasis and cognitive consequences of sleep loss. Neuron 2009; 61: 213-219.
    • (2009) Neuron , vol.61 , pp. 213-219
    • Halassa, M.M.1    Florian, C.2    Fellin, T.3
  • 45
    • 84882747260 scopus 로고    scopus 로고
    • Astrocyte-derived adenosine modulates increased sleep pressure during inflammatory response
    • Nadjar A, Blutstein T, Aubert A, Laye S, Haydon PG. Astrocyte-derived adenosine modulates increased sleep pressure during inflammatory response. Glia 2013; 61: 724-731.
    • (2013) Glia , vol.61 , pp. 724-731
    • Nadjar, A.1    Blutstein, T.2    Aubert, A.3    Laye, S.4    Haydon, P.G.5
  • 46
    • 84925823910 scopus 로고    scopus 로고
    • Neuronal ensembles sufficient for recovery sleep and the sedative actions of alpha adrenergic agonists
    • Zhang Z, Ferretti V, Guntan I et al. Neuronal ensembles sufficient for recovery sleep and the sedative actions of alpha adrenergic agonists. Nat Neurosci 2015; 18: 553-561.
    • (2015) Nat Neurosci , vol.18 , pp. 553-561
    • Zhang, Z.1    Ferretti, V.2    Guntan, I.3
  • 47
    • 0022970390 scopus 로고
    • Disorganization of the rat activity rhythm by chronic treatment with methamphetamine
    • Honma K, Honma S, Hiroshige T. Disorganization of the rat activity rhythm by chronic treatment with methamphetamine. Physiol Behav 1986; 38: 687-695.
    • (1986) Physiol Behav , vol.38 , pp. 687-695
    • Honma, K.1    Honma, S.2    Hiroshige, T.3
  • 48
    • 0023203621 scopus 로고
    • Activity rhythms in the circadian domain appear in suprachiasmatic nuclei lesioned rats given methamphetamine
    • Honma K, Honma S, Hiroshige T. Activity rhythms in the circadian domain appear in suprachiasmatic nuclei lesioned rats given methamphetamine. Physiol Behav 1987; 40: 767-774.
    • (1987) Physiol Behav , vol.40 , pp. 767-774
    • Honma, K.1    Honma, S.2    Hiroshige, T.3
  • 49
    • 0018742875 scopus 로고
    • Anticipation of 24-hr feeding schedules in rats with lesions of the suprachiasmatic nucleus
    • Stephan FK, Swann JM, Sisk CL. Anticipation of 24-hr feeding schedules in rats with lesions of the suprachiasmatic nucleus. Behav Neural Biol 1979; 25: 346-363.
    • (1979) Behav Neural Biol , vol.25 , pp. 346-363
    • Stephan, F.K.1    Swann, J.M.2    Sisk, C.L.3
  • 50
    • 69849094896 scopus 로고    scopus 로고
    • Food-anticipatory circadian rhythms: concepts and methods
    • Mistlberger RE. Food-anticipatory circadian rhythms: concepts and methods. Eur J Neurosci 2009; 30: 1718-1729.
    • (2009) Eur J Neurosci , vol.30 , pp. 1718-1729
    • Mistlberger, R.E.1
  • 51
    • 0037067652 scopus 로고    scopus 로고
    • Phenotypic rescue of a peripheral clock genetic defect via SCN hierarchical dominance
    • Pando MP, Morse D, Cermakian N, Sassone-Corsi P. Phenotypic rescue of a peripheral clock genetic defect via SCN hierarchical dominance. Cell 2002; 110: 107-117.
    • (2002) Cell , vol.110 , pp. 107-117
    • Pando, M.P.1    Morse, D.2    Cermakian, N.3    Sassone-Corsi, P.4
  • 52
    • 84864584460 scopus 로고    scopus 로고
    • Brain-specific rescue of Clock reveals system-driven transcriptional rhythms in peripheral tissue
    • Hughes ME, Hong HK, Chong JL et al. Brain-specific rescue of Clock reveals system-driven transcriptional rhythms in peripheral tissue. PLoS Genet 2012; 8: e1002835.
    • (2012) PLoS Genet , vol.8 , pp. e1002835
    • Hughes, M.E.1    Hong, H.K.2    Chong, J.L.3
  • 55
    • 75849128795 scopus 로고    scopus 로고
    • A circadian clock in macrophages controls inflammatory immune responses
    • Keller M, Mazuch J, Abraham U et al. A circadian clock in macrophages controls inflammatory immune responses. Proc Natl Acad Sci U S A 2009; 106: 21407-21412.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 21407-21412
    • Keller, M.1    Mazuch, J.2    Abraham, U.3
  • 56
    • 84905727517 scopus 로고    scopus 로고
    • An epithelial circadian clock controls pulmonary inflammation and glucocorticoid action
    • Gibbs J, Ince L, Matthews L et al. An epithelial circadian clock controls pulmonary inflammation and glucocorticoid action. Nat Med 2014; 20: 919-926.
    • (2014) Nat Med , vol.20 , pp. 919-926
    • Gibbs, J.1    Ince, L.2    Matthews, L.3
  • 57
    • 84920724791 scopus 로고    scopus 로고
    • Tissue-resident macrophage enhancer landscapes are shaped by the local microenvironment
    • Lavin Y, Winter D, Blecher-Gonen R et al. Tissue-resident macrophage enhancer landscapes are shaped by the local microenvironment. Cell 2014; 159: 1312-1326.
    • (2014) Cell , vol.159 , pp. 1312-1326
    • Lavin, Y.1    Winter, D.2    Blecher-Gonen, R.3
  • 58
    • 84907479665 scopus 로고    scopus 로고
    • T cell memory. A local macrophage chemokine network sustains protective tissue-resident memory CD4 T cells
    • Iijima N, Iwasaki A. T cell memory. A local macrophage chemokine network sustains protective tissue-resident memory CD4 T cells. Science 2014; 346: 93-98.
    • (2014) Science , vol.346 , pp. 93-98
    • Iijima, N.1    Iwasaki, A.2


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