Sympathetic Neuro-adipose Connections Mediate Leptin-Driven Lipolysis

Cell

Volumn 163, Issue 1, 2015, Pages 84-94

  Zeng, Wenwen ^b   Pirzgalska, Roksana M ^a   Pereira, Mafalda M A ^a   Kubasova, Nadiya ^a   Barateiro, Andreia ^a,d   Seixas, Elsa ^a   Lu, Yi Hsueh ^b   Kozlova, Albina ^b   Voss, Henning ^c   Martins, Gabriel G ^a   Friedman, Jeffrey M ^b   Domingos, Ana I ^a  

^a INSTITUTO GULBENKIAN DE CIÊNCIA   (Portugal)

^b ROCKEFELLER UNIVERSITY   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

^d RESEARCH INSTITUTE FOR MEDICINES IMED ULISBOA   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE BETA MONOOXYGENASE; HORMONE SENSITIVE LIPASE; LEPTIN; BETA ADRENERGIC RECEPTOR;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CATECHOLAMINE SYNTHESIS; CELL JUNCTION; CELL STIMULATION; CONTROLLED STUDY; DRUG MECHANISM; LIPOLYSIS; MOUSE; MULTIPHOTON MICROSCOPY; NONHUMAN; OPTOGENETICS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SYMPATHETIC INNERVATION; SYMPATHETIC NERVE CELL; WHITE ADIPOSE TISSUE; ADRENERGIC SYSTEM; ANIMAL; HUMAN; INNERVATION; METABOLISM; PHOSPHORYLATION;

ADIPOSE TISSUE, WHITE; ANIMALS; HUMANS; LEPTIN; LIPOLYSIS; MICE; PHOSPHORYLATION; RECEPTORS, ADRENERGIC, BETA; SYMPATHETIC NERVOUS SYSTEM;

EID: 84944733460     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2015.08.055     Document Type: Article

References (40)

1. K. Arvaniti, Y. Deshaies, and D. Richard Effect of leptin on energy balance does not require the presence of intact adrenals Am. J. Physiol. 275 1998 R105 R111
2. S. Awad, D. Constantin-Teodosiu, I.A. Macdonald, and D.N. Lobo Short-term starvation and mitochondrial dysfunction - a possible mechanism leading to postoperative insulin resistance Clin. Nutr. 28 2009 497 509
3. E.S. Bachman, H. Dhillon, C.Y. Zhang, S. Cinti, A.C. Bianco, B.K. Kobilka, and B.B. Lowell betaAR signaling required for diet-induced thermogenesis and obesity resistance Science 297 2002 843 845
4. T.J. Bartness, and C.K. Song Thematic review series: adipocyte biology. Sympathetic and sensory innervation of white adipose tissue J. Lipid Res. 48 2007 1655 1672
5. T.J. Bartness, C. Kay Song, H. Shi, R.R. Bowers, and M.T. Foster Brain-adipose tissue cross talk Proc. Nutr. Soc. 64 2005 53 64
6. D.L. Brasaemle Thematic review series: adipocyte biology. The perilipin family of structural lipid droplet proteins: stabilization of lipid droplets and control of lipolysis J. Lipid Res. 48 2007 2547 2559
7. T. Buch, F.L. Heppner, C. Tertilt, T.J. Heinen, M. Kremer, F.T. Wunderlich, S. Jung, and A. Waisman A Cre-inducible diphtheria toxin receptor mediates cell lineage ablation after toxin administration Nat. Methods 2 2005 419 426
8. J.W. Correll Adipose tissue: ability to respond to nerve stimulation in vitro Science 140 1963 387 388
9. I. Daou, A.H. Tuttle, G. Longo, J.S. Wieskopf, R.P. Bonin, A.R. Ase, J.N. Wood, Y. De Koninck, A. Ribeiro-da-Silva, J.S. Mogil, and P. Séguéla Remote optogenetic activation and sensitization of pain pathways in freely moving mice J. Neurosci. 33 2013 18631 18640
10. J. Dempersmier, A. Sambeat, O. Gulyaeva, S.M. Paul, C.S. Hudak, H.F. Raposo, H.Y. Kwan, C. Kang, R.H. Wong, and H.S. Sul Cold-inducible Zfp516 activates UCP1 transcription to promote browning of white fat and development of brown fat Mol. Cell 57 2015 235 246
11. Y.M. Ding, J.D. Jaumotte, A.P. Signore, and M.J. Zigmond Effects of 6-hydroxydopamine on primary cultures of substantia nigra: specific damage to dopamine neurons and the impact of glial cell line-derived neurotrophic factor J. Neurochem. 89 2004 776 787
12. G.T. Dodd, S. Decherf, K. Loh, S.E. Simonds, F. Wiede, E. Balland, T.L. Merry, H. Münzberg, Z.Y. Zhang, B.B. Kahn, and et al. Leptin and insulin act on POMC neurons to promote the browning of white fat Cell 160 2015 88 104
13. A.I. Domingos, J. Vaynshteyn, H.U. Voss, X. Ren, V. Gradinaru, F. Zang, K. Deisseroth, I.E. de Araujo, and J. Friedman Leptin regulates the reward value of nutrient Nat. Neurosci. 14 2011 1562 1568
14. A.I. Domingos, A. Sordillo, M.O. Dietrich, Z.W. Liu, L.A. Tellez, J. Vaynshteyn, J.G. Ferreira, M.I. Ekstrand, T.L. Horvath, I.E. de Araujo, and J.M. Friedman Hypothalamic melanin concentrating hormone neurons communicate the nutrient value of sugar eLife 2 2013 e01462
15. M. Elia, R.J. Stubbs, and C.J. Henry Differences in fat, carbohydrate, and protein metabolism between lean and obese subjects undergoing total starvation Obes. Res. 7 1999 597 604
16. J.M. Friedman, and J.L. Halaas Leptin and the regulation of body weight in mammals Nature 395 1998 763 770
17. A. Giordano, M. Morroni, G. Santone, G.F. Marchesi, and S. Cinti Tyrosine hydroxylase, neuropeptide Y, substance P, calcitonin gene-related peptide and vasoactive intestinal peptide in nerves of rat periovarian adipose tissue: an immunohistochemical and ultrastructural investigation J. Neurocytol. 25 1996 125 136
18. A. Giordano, A. Frontini, I. Murano, C. Tonello, M.A. Marino, M.O. Carruba, E. Nisoli, and S. Cinti Regional-dependent increase of sympathetic innervation in rat white adipose tissue during prolonged fasting J. Histochem. Cytochem. 53 2005 679 687
19. M. Giralt, and F. Villarroya White, brown, beige/brite: different adipose cells for different functions? Endocrinology 154 2013 2992 3000
20. E.J. Gualda, T. Vale, P. Almada, J.A. Feijó, G.G. Martins, and N. Moreno OpenSpinMicroscopy: an open-source integrated microscopy platform Nat. Methods 10 2013 599 600
21. J.L. Halaas, K.S. Gajiwala, M. Maffei, S.L. Cohen, B.T. Chait, D. Rabinowitz, R.L. Lallone, S.K. Burley, and J.M. Friedman Weight-reducing effects of the plasma protein encoded by the obese gene Science 269 1995 543 546
22. J.L. Halaas, C. Boozer, J. Blair-West, N. Fidahusein, D.A. Denton, and J.M. Friedman Physiological response to long-term peripheral and central leptin infusion in lean and obese mice Proc. Natl. Acad. Sci. USA 94 1997 8878 8883
23. F. Helmchen, and W. Denk Deep tissue two-photon microscopy Nat. Methods 2 2005 932 940
24. P. Holzer Capsaicin: cellular targets, mechanisms of action, and selectivity for thin sensory neurons Pharmacol. Rev. 43 1991 143 201
25. M. Koffler, and E.S. Kisch Starvation diet and very-low-calorie diets may induce insulin resistance and overt diabetes mellitus J. Diabetes Complications 10 1996 109 112
26. L. Landsberg, M.E. Saville, and J.B. Young Sympathoadrenal system and regulation of thermogenesis Am. J. Physiol. 247 1984 E181 E189
27. J.M. Montez, A. Soukas, E. Asilmaz, G. Fayzikhodjaeva, G. Fantuzzi, and J.M. Friedman Acute leptin deficiency, leptin resistance, and the physiologic response to leptin withdrawal Proc. Natl. Acad. Sci. USA 102 2005 2537 2542
28. W.P. Newman, and R.G. Brodows Insulin action during acute starvation: evidence for selective insulin resistance in normal man Metabolism 32 1983 590 596
29. K.D. Nguyen, Y. Qiu, X. Cui, Y.P. Goh, J. Mwangi, T. David, L. Mukundan, F. Brombacher, R.M. Locksley, and A. Chawla Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis Nature 480 2011 104 108
30. L. Petreanu, D. Huber, A. Sobczyk, and K. Svoboda Channelrhodopsin-2-assisted circuit mapping of long-range callosal projections Nat. Neurosci. 10 2007 663 668
31. L. Quintana, and J. Sharpe Optical projection tomography of vertebrate embryo development Cold Spring Harb. Protoc. 2011 2011 586 594
32. J. Rafael, and A.W. Herling Leptin effect in ob/ob mice under thermoneutral conditions depends not necessarily on central satiation Am. J. Physiol. Regul. Integr. Comp. Physiol. 278 2000 R790 R795
33. K. Rezai-Zadeh, and H. Münzberg Integration of sensory information via central thermoregulatory leptin targets Physiol. Behav. 121 2013 49 55
34. P.J. Scarpace, and M. Matheny Leptin induction of UCP1 gene expression is dependent on sympathetic innervation Am. J. Physiol. 275 1998 E259 E264
35. J. Schindelin, I. Arganda-Carreras, E. Frise, V. Kaynig, M. Longair, T. Pietzsch, S. Preibisch, C. Rueden, S. Saalfeld, B. Schmid, and et al. Fiji: an open-source platform for biological-image analysis Nat. Methods 9 2012 676 682
36. G. Tavernier, M. Jimenez, J.P. Giacobino, N. Hulo, M. Lafontan, P. Muzzin, and D. Langin Norepinephrine induces lipolysis in beta1/beta2/beta3-adrenoceptor knockout mice Mol. Pharmacol. 68 2005 793 799
37. G.E. Thompson Vascular and lipolytic responses of the inguinal fat pad of the sheep to adrenergic stimulation, and the effects of denervation and autotransplantation Q. J. Exp. Physiol. 71 1986 559 567
38. S. Vrontou, A.M. Wong, K.K. Rau, H.R. Koerber, and D.J. Anderson Genetic identification of C fibres that detect massage-like stroking of hairy skin in vivo Nature 493 2013 669 673
39. S.P. Weisberg, D. McCann, M. Desai, M. Rosenbaum, R.L. Leibel, and A.W. Ferrante Jr. Obesity is associated with macrophage accumulation in adipose tissue J. Clin. Invest. 112 2003 1796 1808
40. T.G. Youngstrom, and T.J. Bartness Catecholaminergic innervation of white adipose tissue in Siberian hamsters Am. J. Physiol. 268 1995 R744 R751