Loss of Aβ43 Production Caused by Presenilin-1 Mutations in the Knockin Mouse Brain

Neuron

Volumn 90, Issue 2, 2016, Pages 417-422

  Xia, Dan ^a   Kelleher, Raymond J ^a,b   Shen, Jie ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; AMYLOID BETA PROTEIN[1-43]; GAMMA SECRETASE; PRESENILIN 1; UNCLASSIFIED DRUG; AMYLOID BETA-PROTEIN (1-43); PEPTIDE FRAGMENT; PRESENILIN 1, MOUSE; SECRETASE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN NERVE CELL; CELL SURVIVAL; CONTROLLED STUDY; EMBRYO; GENE MUTATION; GENE SILENCING; HOMOZYGOTE; LEARNING DISORDER; MEMORY DISORDER; MOUSE; NONHUMAN; PHENOTYPE; PRESENILIN 1 GENE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SYNTHESIS; STEADY STATE; SYNAPSE; ANIMAL; BIOSYNTHESIS; GENE TARGETING; GENETICS; METABOLISM; MUTATION;

AMYLOID BETA-PEPTIDES; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; BRAIN; GENE KNOCK-IN TECHNIQUES; HOMOZYGOTE; MICE; MUTATION; PEPTIDE FRAGMENTS; PRESENILIN-1;

EID: 84963768320     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2016.03.009     Document Type: Article

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