-
1
-
-
79151478555
-
Type 2 diabetes as an inflammatory disease
-
M.Y.Donath, S.E.Shoelson Type 2 diabetes as an inflammatory disease. Nat Rev Immunol. 2011;11:98–107.•• This study provides an excellent overview of inflammatory mechanisms associated to T2D.
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 98-107
-
-
Donath, M.Y.1
Shoelson, S.E.2
-
3
-
-
84983132688
-
Treating rheumatological diseases and co-morbidities with interleukin-1 blocking therapies
-
G.Cavalli, C.A.Dinarello. Treating rheumatological diseases and co-morbidities with interleukin-1 blocking therapies. Rheumatology (Oxford). 2015;54:2134–2144.• An Interesting review of efficacy of interleukin-1 blocking therapies in the treatment of rheumatological diseases and co-morbidities.
-
(2015)
Rheumatology (Oxford)
, vol.54
, pp. 2134-2144
-
-
Cavalli, G.1
Dinarello, C.A.2
-
4
-
-
84871147265
-
Traditional cardiovascular risk factors, inflammation and cardiovascular risk in rheumatoid arthritis
-
K.P.Liao, D.H.Solomon. Traditional cardiovascular risk factors, inflammation and cardiovascular risk in rheumatoid arthritis. Rheumatology (Oxford). 2013;52:45–52.
-
(2013)
Rheumatology (Oxford)
, vol.52
, pp. 45-52
-
-
Liao, K.P.1
Solomon, D.H.2
-
5
-
-
27744603002
-
Hypoxia regulates macrophage functions in inflammation
-
C.Murdoch, M.Muthana, C.E.Lewis. Hypoxia regulates macrophage functions in inflammation. J Immunol. 2005;175:6257–6263.
-
(2005)
J Immunol
, vol.175
, pp. 6257-6263
-
-
Murdoch, C.1
Muthana, M.2
Lewis, C.E.3
-
6
-
-
0141425768
-
Hypoxia-induced gene expression in human macrophages: implications for ischemic tissues and hypoxia-regulated gene therapy
-
B.Burke, A.Giannoudis, K.P.Corke, et al. Hypoxia-induced gene expression in human macrophages: implications for ischemic tissues and hypoxia-regulated gene therapy. Am J Pathol. 2003;163:1233–1243.
-
(2003)
Am J Pathol
, vol.163
, pp. 1233-1243
-
-
Burke, B.1
Giannoudis, A.2
Corke, K.P.3
-
7
-
-
84883530920
-
Macrophages and islet inflammation in type 2 diabetes
-
K.Eguchi, I.Manabe. Macrophages and islet inflammation in type 2 diabetes. Diabetes Obes Metab. 2013;15:152–158.• An interesting review of role of macrophages in T2D.
-
(2013)
Diabetes Obes Metab
, vol.15
, pp. 152-158
-
-
Eguchi, K.1
Manabe, I.2
-
8
-
-
0023201153
-
Interleukin 1 induces interleukin 1. I. Induction of circulating interleukin 1in rabbits in vivo and in human mononuclear cells in vitro
-
C.A.Dinarello, T.Ikejima, S.J.Warner, et al. Interleukin 1 induces interleukin 1. I. Induction of circulating interleukin 1in rabbits in vivo and in human mononuclear cells in vitro. J Immunol. 1987;139:1902–1910.
-
(1987)
J Immunol
, vol.139
, pp. 1902-1910
-
-
Dinarello, C.A.1
Ikejima, T.2
Warner, S.J.3
-
10
-
-
84890235827
-
The interleukin-1 family: back to the future
-
C.Garlanda, C.A.Dinarello, A.Mantovani. The interleukin-1 family: back to the future. Immunity. 2013;39:1003–1018.
-
(2013)
Immunity
, vol.39
, pp. 1003-1018
-
-
Garlanda, C.1
Dinarello, C.A.2
Mantovani, A.3
-
11
-
-
84892869580
-
Overview of the interleukin-1 family of ligands and receptors
-
C.A.Dinarello. Overview of the interleukin-1 family of ligands and receptors. Semin Immunol. 2013;25:389–393.
-
(2013)
Semin Immunol
, vol.25
, pp. 389-393
-
-
Dinarello, C.A.1
-
12
-
-
84928822514
-
The role of IL-1β in the bone loss during rheumatic diseases
-
P.Ruscitti, P.Cipriani, F.Carubbi, et al. The role of IL-1β in the bone loss during rheumatic diseases. Mediators Inflamm. 2015;2015:782382.
-
(2015)
Mediators Inflamm
, vol.2015
, pp. 782382
-
-
Ruscitti, P.1
Cipriani, P.2
Carubbi, F.3
-
13
-
-
7044277863
-
The role of interleukin-1 in bone resorption in rheumatoid arthritis
-
V.Strand, A.F.Kavanaugh. The role of interleukin-1 in bone resorption in rheumatoid arthritis. Rheumatology (Oxford). 2004;43:iii10–iii16.
-
(2004)
Rheumatology (Oxford)
, vol.43
, pp. iii10-iii16
-
-
Strand, V.1
Kavanaugh, A.F.2
-
14
-
-
0035304643
-
Cytokine imbalance in the pathogenesis of rheumatoid arthritis: the role of interleukin-1 receptor antagonist
-
W.P.Arend. Cytokine imbalance in the pathogenesis of rheumatoid arthritis: the role of interleukin-1 receptor antagonist. Semin Arthritis Rheum. 2001;30:1–6.
-
(2001)
Semin Arthritis Rheum
, vol.30
, pp. 1-6
-
-
Arend, W.P.1
-
15
-
-
0033391920
-
Pathogenesis of joint damage in rheumatoid arthritis: evidence of a dominant role for interleukin-I
-
W.B.van den Berg, B.Bresnihan. Pathogenesis of joint damage in rheumatoid arthritis: evidence of a dominant role for interleukin-I. Baillieres Best Pract Res Clin Rheumatol. 1999;13:577–597.
-
(1999)
Baillieres Best Pract Res Clin Rheumatol
, vol.13
, pp. 577-597
-
-
van den Berg, W.B.1
Bresnihan, B.2
-
17
-
-
0036735138
-
Blocking the effects of IL-1 in rheumatoid arthritis protects bone and cartilage
-
S.B.Abramson, A.Amin. Blocking the effects of IL-1 in rheumatoid arthritis protects bone and cartilage. Rheumatology. 2002;41:972–980.
-
(2002)
Rheumatology
, vol.41
, pp. 972-980
-
-
Abramson, S.B.1
Amin, A.2
-
18
-
-
0036839553
-
Bone destruction in arthritis
-
E.M.Gravallese. Bone destruction in arthritis. Ann Rheum Dis. 2002;61:ii84–86.
-
(2002)
Ann Rheum Dis
, vol.61
, pp. ii84-ii86
-
-
Gravallese, E.M.1
-
19
-
-
0031253812
-
Constitutive intra-articular expression of human IL-1 beta following gene transfer to rabbit synovium produces all major pathologies of human rheumatoid arthritis
-
S.C.Ghivizzani, R.Kang, H.I.Georgescu, et al. Constitutive intra-articular expression of human IL-1 beta following gene transfer to rabbit synovium produces all major pathologies of human rheumatoid arthritis. J Immunol. 1997;1:3604–3612.
-
(1997)
J Immunol
, vol.1
, pp. 3604-3612
-
-
Ghivizzani, S.C.1
Kang, R.2
Georgescu, H.I.3
-
20
-
-
0034677123
-
Development of chronic inflammatory arthropathy resembling rheumatoid arthritis in interleukin 1 receptor antagonist-deficient mice
-
R.Horai, S.Saijo, H.Tanioka, et al. Development of chronic inflammatory arthropathy resembling rheumatoid arthritis in interleukin 1 receptor antagonist-deficient mice. J Exp Med. 2000;191:313–320.
-
(2000)
J Exp Med
, vol.191
, pp. 313-320
-
-
Horai, R.1
Saijo, S.2
Tanioka, H.3
-
21
-
-
0034122050
-
Synovial tissue in rheumatoid arthritis is a source of osteoclast differentiation factor
-
E.M.Gravallese, C.Manning, A.Tsay, et al. Synovial tissue in rheumatoid arthritis is a source of osteoclast differentiation factor. Arthritis Rheum. 2000;43:250–258.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 250-258
-
-
Gravallese, E.M.1
Manning, C.2
Tsay, A.3
-
22
-
-
0034121039
-
Involvement of receptor activator of nuclear factor kappaB ligand/osteoclast differentiation factor in osteoclastogenesis from synoviocytes in rheumatoid arthritis
-
H.Takayanagi, H.Iizuka, T.Juji, et al. Involvement of receptor activator of nuclear factor kappaB ligand/osteoclast differentiation factor in osteoclastogenesis from synoviocytes in rheumatoid arthritis. Arthritis Rheum. 2000;43:259–269.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 259-269
-
-
Takayanagi, H.1
Iizuka, H.2
Juji, T.3
-
23
-
-
42949175161
-
Anticytokine treatment of established type II collagen-induced arthritis in DBA/1 mice: a comparative study using anti-TNFalpha, anti-IL-1alpha/beta and IL-1Ra
-
L.A.Joosten, M.M.Helsen, F.A.van de Loo, et al. Anticytokine treatment of established type II collagen-induced arthritis in DBA/1 mice: a comparative study using anti-TNFalpha, anti-IL-1alpha/beta and IL-1Ra. Arthritis Rheum. 2008;58:S110–S122.
-
(2008)
Arthritis Rheum
, vol.58
, pp. S110-S122
-
-
Joosten, L.A.1
Helsen, M.M.2
van de Loo, F.A.3
-
24
-
-
0032752705
-
IL-1 alpha beta blockade prevents cartilage and bone destruction in murine type II collagen-induced arthritis, whereas TNF-alpha blockade only ameliorates joint inflammation
-
L.A.Joosten, M.M.Helsen, T.Saxne, et al. IL-1 alpha beta blockade prevents cartilage and bone destruction in murine type II collagen-induced arthritis, whereas TNF-alpha blockade only ameliorates joint inflammation. J Immunol. 1999;163:5049–5055.
-
(1999)
J Immunol
, vol.163
, pp. 5049-5055
-
-
Joosten, L.A.1
Helsen, M.M.2
Saxne, T.3
-
25
-
-
0030071084
-
Suppression of experimental arthritis by gene transfer of interleukin 1 receptor antagonist cDNA
-
S.S.Makarov, J.C.Olsen, W.N.Johnston, et al. Suppression of experimental arthritis by gene transfer of interleukin 1 receptor antagonist cDNA. Proc Natl Acad Sci U S A. 1996;93:402–406.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 402-406
-
-
Makarov, S.S.1
Olsen, J.C.2
Johnston, W.N.3
-
26
-
-
0029967052
-
Suppression of antigen-induced arthritis in rabbits by ex vivo gene therapy
-
K.Otani, I.Nita, W.Macaulay, et al. Suppression of antigen-induced arthritis in rabbits by ex vivo gene therapy. J Immunol. 1996;156:3558–3562.
-
(1996)
J Immunol
, vol.156
, pp. 3558-3562
-
-
Otani, K.1
Nita, I.2
Macaulay, W.3
-
27
-
-
0031112232
-
Human IL-1Ra gene transfer into human synovial fibroblasts is chondroprotective
-
U.Müller-Ladner, C.R.Roberts, B.N.Franklin, et al. Human IL-1Ra gene transfer into human synovial fibroblasts is chondroprotective. J Immunol. 1997;158:3492–3498.
-
(1997)
J Immunol
, vol.158
, pp. 3492-3498
-
-
Müller-Ladner, U.1
Roberts, C.R.2
Franklin, B.N.3
-
28
-
-
84869210018
-
Managing macrophages in rheumatoid arthritis by reform or removal
-
J.Li, H.C.Hsu, J.D.Mountz. Managing macrophages in rheumatoid arthritis by reform or removal. Curr Rheumatol Rep. 2012;14:445–454.
-
(2012)
Curr Rheumatol Rep
, vol.14
, pp. 445-454
-
-
Li, J.1
Hsu, H.C.2
Mountz, J.D.3
-
29
-
-
7644231561
-
The chemokine system in diverse forms of macrophage activation and polarization
-
A.Mantovani, A.Sica, S.Sozzani, et al. The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol. 2004;25:677–686.
-
(2004)
Trends Immunol
, vol.25
, pp. 677-686
-
-
Mantovani, A.1
Sica, A.2
Sozzani, S.3
-
30
-
-
56749174940
-
Exploring the full spectrum of macrophage activation
-
D.M.Mosser, J.P.Edwards. Exploring the full spectrum of macrophage activation. Nat Rev Immunol. 2008;8:958–969.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 958-969
-
-
Mosser, D.M.1
Edwards, J.P.2
-
31
-
-
84885415450
-
MHC class II polymorphisms, autoreactive T-cells, and autoimmunity
-
S.Tsai, P.Santamaria. MHC class II polymorphisms, autoreactive T-cells, and autoimmunity. Front Immunol. 2013;4:321.
-
(2013)
Front Immunol
, vol.4
, pp. 321
-
-
Tsai, S.1
Santamaria, P.2
-
32
-
-
76649105764
-
Immunotherapy of rheumatoid arthritis targeting inflammatory cytokines and autoreactive T cells
-
G.Chen. Immunotherapy of rheumatoid arthritis targeting inflammatory cytokines and autoreactive T cells. Arch Immunol Ther Exp (Warsz). 2010;58:27–36.
-
(2010)
Arch Immunol Ther Exp (Warsz)
, vol.58
, pp. 27-36
-
-
Chen, G.1
-
33
-
-
44949118517
-
Anakinra for rheumatoid arthritis
-
M.Mertens, J.A.Singh. Anakinra for rheumatoid arthritis. Cochrane Database Syst Rev. 2009;1:CD005121.• A systematic review of anakinra efficacy in RA patients.
-
(2009)
Cochrane Database Syst Rev
, vol.1
, pp. CD005121
-
-
Mertens, M.1
Singh, J.A.2
-
34
-
-
66649102432
-
Canakinumab in CAPS study group: use of canakinumab in the cryopyrin-associated periodic syndrome
-
H.J.Lachmann, I.Kone-Paut, J.B.Kuemmerle-Deschner, et al. Canakinumab in CAPS study group: use of canakinumab in the cryopyrin-associated periodic syndrome. N Engl J Med. 2009;360:2416–2425.
-
(2009)
N Engl J Med
, vol.360
, pp. 2416-2425
-
-
Lachmann, H.J.1
Kone-Paut, I.2
Kuemmerle-Deschner, J.B.3
-
35
-
-
46149100545
-
The human anti-IL-1beta monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis
-
R.Alten, H.Gram, L.A.Joosten, et al. The human anti-IL-1beta monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis. Arthritis Res Ther. 2008;10:R67.
-
(2008)
Arthritis Res Ther
, vol.10
, pp. R67
-
-
Alten, R.1
Gram, H.2
Joosten, L.A.3
-
36
-
-
80052189130
-
Efficacy and safety of the human anti-IL-1β monoclonal antibody canakinumab in rheumatoid arthritis: results of a 12-week, Phase II, dose-finding study
-
R.Alten, J.Gomez-Reino, P.Durez, et al. Efficacy and safety of the human anti-IL-1β monoclonal antibody canakinumab in rheumatoid arthritis: results of a 12-week, Phase II, dose-finding study. BMC Musculoskelet Disord. 2011;12:153.
-
(2011)
BMC Musculoskelet Disord
, vol.12
, pp. 153
-
-
Alten, R.1
Gomez-Reino, J.2
Durez, P.3
-
37
-
-
0036738398
-
Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets
-
K.Maedler, P.Sergeev, F.Ris, et al. Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets. J Clin Invest. 2002;110:851–860.•• This study provides the first description of the role of IL-1β in T2D.
-
(2002)
J Clin Invest
, vol.110
, pp. 851-860
-
-
Maedler, K.1
Sergeev, P.2
Ris, F.3
-
38
-
-
33644669584
-
Is there a role for locally produced interleukin-1 in the deleterious effects of high glucose or the type 2 diabetes milieu to human pancreatic islets?
-
N.Welsh, M.Cnop, I.Kharroubi, et al. Is there a role for locally produced interleukin-1 in the deleterious effects of high glucose or the type 2 diabetes milieu to human pancreatic islets? Diabetes. 2005;54::3238–3244.
-
(2005)
Diabetes
, vol.54
, pp. 3238-3244
-
-
Welsh, N.1
Cnop, M.2
Kharroubi, I.3
-
39
-
-
75649096002
-
Thioredoxin-interacting protein links oxidative stress to inflammasome activation
-
Epub, Dec
-
R.Zhou, A.Tardivel, B.Thorens. et al. Thioredoxin-interacting protein links oxidative stress to inflammasome activation. Nat Immunol. 2010 Feb;11(2):136–140. doi:10.1038/ni.1831. Epub 2009 Dec20.
-
(2010)
Nat Immunol
, vol.11
, Issue.2
, pp. 136-140
-
-
Zhou, R.1
Tardivel, A.2
Thorens, B.3
-
40
-
-
77956958947
-
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1beta in type 2 diabetes
-
S.L.Masters, A.Dunne, S.L.Subramanian, et al. Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1beta in type 2 diabetes. Nat Immunol. 2010;11:897–904.
-
(2010)
Nat Immunol
, vol.11
, pp. 897-904
-
-
Masters, S.L.1
Dunne, A.2
Subramanian, S.L.3
-
41
-
-
84948798570
-
Islet amyloid polypeptide: structure, function, and pathophysiology
-
R.Akter, P.Cao, H.Noor, et al. Islet amyloid polypeptide: structure, function, and pathophysiology. J Diabetes Res. 2016;2016:2798269.
-
(2016)
J Diabetes Res
, vol.2016
, pp. 2798269
-
-
Akter, R.1
Cao, P.2
Noor, H.3
-
42
-
-
84904730993
-
Understanding and modulating the toll like receptors (TLRs) and NOD like receptors (NLRs) cross talk in type 2 diabetes
-
B.Prajapati, P.K.Jena, P.Rajput, et al. Understanding and modulating the toll like receptors (TLRs) and NOD like receptors (NLRs) cross talk in type 2 diabetes. Curr Diabetes Rev. 2014;10:190–200.
-
(2014)
Curr Diabetes Rev
, vol.10
, pp. 190-200
-
-
Prajapati, B.1
Jena, P.K.2
Rajput, P.3
-
43
-
-
74549184092
-
The NLRP3 inflammasome: a sensor for metabolic danger?
-
K.Schroder, R.Zhou, J.Tschopp. The NLRP3 inflammasome: a sensor for metabolic danger? Science. 2010;327:296–300.
-
(2010)
Science
, vol.327
, pp. 296-300
-
-
Schroder, K.1
Zhou, R.2
Tschopp, J.3
-
44
-
-
53749100698
-
Increased interleukin (IL)-1beta messenger ribonucleic acid expression in beta -cells of individuals with type 2 diabetes and regulation of IL-1beta in human islets by glucose and autostimulation
-
M.Böni-Schnetzler, J.Thorne, G.Parnaud, et al. Increased interleukin (IL)-1beta messenger ribonucleic acid expression in beta -cells of individuals with type 2 diabetes and regulation of IL-1beta in human islets by glucose and autostimulation. J Clin Endocrinol Metab. 2008;93:4065–4074.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, pp. 4065-4074
-
-
Böni-Schnetzler, M.1
Thorne, J.2
Parnaud, G.3
-
45
-
-
71949118923
-
Free fatty acids induce a proinflammatory response in islets via the abundantly expressed interleukin-1 receptor I
-
M.Boni-Schnetzler, S.Boller, S.Debray, et al. Free fatty acids induce a proinflammatory response in islets via the abundantly expressed interleukin-1 receptor I. Endocrinology. 2009;150:5218–5229.
-
(2009)
Endocrinology
, vol.150
, pp. 5218-5229
-
-
Boni-Schnetzler, M.1
Boller, S.2
Debray, S.3
-
46
-
-
2542541353
-
Leptin modulates β cell expression of IL-1 receptor antagonist and release of IL-1β in human islets
-
K.Maedler, P.Sergeev, J.A.Ehses, et al. Leptin modulates β cell expression of IL-1 receptor antagonist and release of IL-1β in human islets. Proc Natl Acad Sci USA. 2004;101:8138–8143.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 8138-8143
-
-
Maedler, K.1
Sergeev, P.2
Ehses, J.A.3
-
47
-
-
0033034807
-
Hyperglycemia-induced β-cell apoptosis in pancreatic islets of Psammomys obesus during development of diabetes
-
M.Y.Donath, D.J.Gross, E.Cerasi, et al. Hyperglycemia-induced β-cell apoptosis in pancreatic islets of Psammomys obesus during development of diabetes. Diabetes. 1999;48:738–744.
-
(1999)
Diabetes
, vol.48
, pp. 738-744
-
-
Donath, M.Y.1
Gross, D.J.2
Cerasi, E.3
-
48
-
-
84883546693
-
Role of pancreatic β-cell death and inflammation in diabetes
-
W.Quan, E.K.Jo, M.S.Lee. Role of pancreatic β-cell death and inflammation in diabetes. Diabetes Obes Metab. 2013;15:141–151.
-
(2013)
Diabetes Obes Metab
, vol.15
, pp. 141-151
-
-
Quan, W.1
Jo, E.K.2
Lee, M.S.3
-
50
-
-
33645211764
-
A transient microenvironment loaded mainly with macrophages in the early developing human pancreas
-
L.Banaei-Bouchareb, M.Peuchmaur, P.Czernichow, et al. A transient microenvironment loaded mainly with macrophages in the early developing human pancreas. J Endocrinol. 2006;188:467–480.
-
(2006)
J Endocrinol
, vol.188
, pp. 467-480
-
-
Banaei-Bouchareb, L.1
Peuchmaur, M.2
Czernichow, P.3
-
51
-
-
84937738268
-
Macrophages are essential for CTGF-mediated adult β-cell proliferation after injury
-
K.G.Riley, R.C.Pasek, M.F.Maulis, et al. Macrophages are essential for CTGF-mediated adult β-cell proliferation after injury. Mol Metab. 2015;4:584–591.
-
(2015)
Mol Metab
, vol.4
, pp. 584-591
-
-
Riley, K.G.1
Pasek, R.C.2
Maulis, M.F.3
-
52
-
-
0007882598
-
The mononuclear phagocyte system of the mouse defined by immunohistochemical localization of antigen F4/80. Macrophages of endocrine organs
-
D.A.Hume, D.Halpin, S.Charlton, et al. The mononuclear phagocyte system of the mouse defined by immunohistochemical localization of antigen F4/80. Macrophages of endocrine organs. Proc Natl Acad Sci USA. 1984;81:4174–4177.
-
(1984)
Proc Natl Acad Sci USA
, vol.81
, pp. 4174-4177
-
-
Hume, D.A.1
Halpin, D.2
Charlton, S.3
-
53
-
-
84859449180
-
Saturated fatty acid and TLR signaling link β cell dysfunction and islet inflammation
-
K.Eguchi, I.Manabe, Y.Oishi-Tanaka, et al. Saturated fatty acid and TLR signaling link β cell dysfunction and islet inflammation. Cell Metab. 2012;15:518–533.
-
(2012)
Cell Metab
, vol.15
, pp. 518-533
-
-
Eguchi, K.1
Manabe, I.2
Oishi-Tanaka, Y.3
-
54
-
-
34547119919
-
High glucose induces IL-1beta expression in human monocytes: mechanistic insights
-
M.R.Dasu, S.Devaraj, I.Jialal. High glucose induces IL-1beta expression in human monocytes: mechanistic insights. Am J Physiol Endocrinol Metab. 2007;293:E337–E346.
-
(2007)
Am J Physiol Endocrinol Metab
, vol.293
, pp. E337-E346
-
-
Dasu, M.R.1
Devaraj, S.2
Jialal, I.3
-
55
-
-
84872018875
-
Upregulated NLRP3 inflammasome activation in patients with type 2 diabetes
-
Jan
-
H.M.Lee, J.J.Kim, H.J.Kim, et al. Upregulated NLRP3 inflammasome activation in patients with type 2 diabetes. Diabetes. 2013 Jan;62(1):194–204.
-
(2013)
Diabetes
, vol.62
, Issue.1
, pp. 194-204
-
-
Lee, H.M.1
Kim, J.J.2
Kim, H.J.3
-
56
-
-
77955069213
-
Acute cytokine-mediated downregulation of the zinc transporter ZnT8 alters pancreatic beta-cell function
-
M.El Muayed, L.K.Billings, M.R.Raja, et al. Acute cytokine-mediated downregulation of the zinc transporter ZnT8 alters pancreatic beta-cell function. J Endocrinol. 2010;206:159–169.
-
(2010)
J Endocrinol
, vol.206
, pp. 159-169
-
-
El Muayed, M.1
Billings, L.K.2
Raja, M.R.3
-
57
-
-
33750846939
-
Low concentration of interleukin-1beta induces FLICE-inhibitory protein-mediated beta-cell proliferation in human pancreatic islets
-
K.Maedler, D.M.Schumann, N.Sauter, et al. Low concentration of interleukin-1beta induces FLICE-inhibitory protein-mediated beta-cell proliferation in human pancreatic islets. Diabetes. 2006;55:2713–2722.
-
(2006)
Diabetes
, vol.55
, pp. 2713-2722
-
-
Maedler, K.1
Schumann, D.M.2
Sauter, N.3
-
58
-
-
33847250987
-
The Fas pathway is involved in pancreatic beta cell secretory function
-
D.M.Schumann, K.Maedler, I.Franklin, et al. The Fas pathway is involved in pancreatic beta cell secretory function. Proc Natl Acad Sci USA. 2007;104:2861–2866.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 2861-2866
-
-
Schumann, D.M.1
Maedler, K.2
Franklin, I.3
-
59
-
-
0032932324
-
Beta-cell destruction in NOD mice correlates with Fas (CD95) expression on beta-cells and proinflammatory cytokine expression in islets
-
W.Suarez-Pinzon, O.Sorensen, R.C.Bleackley, et al. Beta-cell destruction in NOD mice correlates with Fas (CD95) expression on beta-cells and proinflammatory cytokine expression in islets. Diabetes. 1999;48:21–28.
-
(1999)
Diabetes
, vol.48
, pp. 21-28
-
-
Suarez-Pinzon, W.1
Sorensen, O.2
Bleackley, R.C.3
-
60
-
-
0028979944
-
Interleukin-1 beta-induced stimulation of insulin release in mouse pancreatic islets is related to diacylglycerol production and protein kinase C activation
-
D.L.Eizirik, S.Sandler, N.Welsh, et al. Interleukin-1 beta-induced stimulation of insulin release in mouse pancreatic islets is related to diacylglycerol production and protein kinase C activation. Mol Cell Endocrinol. 1995;111:159–165.
-
(1995)
Mol Cell Endocrinol
, vol.111
, pp. 159-165
-
-
Eizirik, D.L.1
Sandler, S.2
Welsh, N.3
-
61
-
-
81255157471
-
Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells
-
H.Ellingsgaard, I.Hauselmann, B.Schuler, et al. Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells. Nat Med. 2011;17:1481–1489.
-
(2011)
Nat Med
, vol.17
, pp. 1481-1489
-
-
Ellingsgaard, H.1
Hauselmann, I.2
Schuler, B.3
-
62
-
-
84899414605
-
Caspases and inflammasomes in metabolic inflammation
-
A.M.Skeldon, M.Faraj, M.Saleh. Caspases and inflammasomes in metabolic inflammation. Immunol Cell Biol. 2014;92:304–313.• An interesting review of role of caspases and inflammasomes in metabolic inflammation.
-
(2014)
Immunol Cell Biol
, vol.92
, pp. 304-313
-
-
Skeldon, A.M.1
Faraj, M.2
Saleh, M.3
-
63
-
-
84901920026
-
Targeting inflammation in the treatment of type 2 diabetes: time to start
-
M.Y.Donath. Targeting inflammation in the treatment of type 2 diabetes: time to start. Nat Rev Drug Discov. 2014;13:465–476.• An interesting review of immunomodulatory therapies for T2D.
-
(2014)
Nat Rev Drug Discov
, vol.13
, pp. 465-476
-
-
Donath, M.Y.1
-
64
-
-
84878300647
-
AIDA Study Group: interleukin-1 antagonism in type 1 diabetes of recent onset: two multicentre, randomised, double-blind, placebo-controlled trials
-
A.Moran, B.Bundy, D.J.Becker, et al. AIDA Study Group: interleukin-1 antagonism in type 1 diabetes of recent onset: two multicentre, randomised, double-blind, placebo-controlled trials. Lancet. 2013;381:1905–1915.
-
(2013)
Lancet
, vol.381
, pp. 1905-1915
-
-
Moran, A.1
Bundy, B.2
Becker, D.J.3
-
65
-
-
84942194980
-
Current treatment recommendations and considerations for cryopyrin-associated periodic syndrome
-
I.Koné-Paut, C.Galeotti. Current treatment recommendations and considerations for cryopyrin-associated periodic syndrome. Expert Rev Clin Immunol. 2015;11:1083–1092.
-
(2015)
Expert Rev Clin Immunol
, vol.11
, pp. 1083-1092
-
-
Koné-Paut, I.1
Galeotti, C.2
-
66
-
-
84893149037
-
Anakinra for cryopyrin-associated periodic syndrome
-
I.Koné-Paut, C.Galeotti. Anakinra for cryopyrin-associated periodic syndrome. Expert Rev Clin Immunol. 2014;10:7–18.
-
(2014)
Expert Rev Clin Immunol
, vol.10
, pp. 7-18
-
-
Koné-Paut, I.1
Galeotti, C.2
-
67
-
-
34247170807
-
Interleukin-1-receptor antagonist in type 2 diabetes mellitus
-
C.M.Larsen, M.Faulenbach, A.Vaag, et al. Interleukin-1-receptor antagonist in type 2 diabetes mellitus. N Engl J Med. 2007;356:1517–1526.•• A clinical study showed the efficacy of treatment with an IL-1 antagonist in T2D patients.
-
(2007)
N Engl J Med
, vol.356
, pp. 1517-1526
-
-
Larsen, C.M.1
Faulenbach, M.2
Vaag, A.3
-
68
-
-
69549105888
-
Sustained effects of interleukin-1 receptor antagonist treatment in type 2 diabetes
-
C.M.Larsen, M.Faulenbach, A.Vaag, et al. Sustained effects of interleukin-1 receptor antagonist treatment in type 2 diabetes. Diabetes Care. 2009;32:1663–1668.
-
(2009)
Diabetes Care
, vol.32
, pp. 1663-1668
-
-
Larsen, C.M.1
Faulenbach, M.2
Vaag, A.3
-
69
-
-
69549098032
-
IL-1 antagonism reduces hyperglycemia and tissue inflammation in the type 2 diabetic GK rat
-
J.A.Ehses, G.Lacraz, M.H.Giroix, et al. IL-1 antagonism reduces hyperglycemia and tissue inflammation in the type 2 diabetic GK rat. Proc Natl Acad Sci USA. 2009;106:13998–14003.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 13998-14003
-
-
Ehses, J.A.1
Lacraz, G.2
Giroix, M.H.3
-
70
-
-
42449091550
-
The antiinflammatory cytokine interleukin-1 receptor antagonist protects from high-fat diet-induced hyperglycemia
-
N.S.Sauter, F.T.Schulthess, R.Galasso, et al. The antiinflammatory cytokine interleukin-1 receptor antagonist protects from high-fat diet-induced hyperglycemia. Endocrinology. 2008;149:2208–2218.
-
(2008)
Endocrinology
, vol.149
, pp. 2208-2218
-
-
Sauter, N.S.1
Schulthess, F.T.2
Galasso, R.3
-
71
-
-
79960086288
-
Treatment with anakinra improves disposition index but not insulin sensitivity in nondiabetic subjects with the metabolic syndrome: a randomized, double-blind, placebo-controlled study
-
E.J.P.van Asseldonk, R.Stienstra, T.B.Koenen, et al. Treatment with anakinra improves disposition index but not insulin sensitivity in nondiabetic subjects with the metabolic syndrome: a randomized, double-blind, placebo-controlled study. J Clin Endocrinol Metab. 2011;96:2119–2126.
-
(2011)
J Clin Endocrinol Metab
, vol.96
, pp. 2119-2126
-
-
van Asseldonk, E.J.P.1
Stienstra, R.2
Koenen, T.B.3
-
72
-
-
84920420168
-
The interleukin-1 receptor antagonist anakinra improves first-phase insulin secretion and insulinogenic index in subjects with impaired glucose tolerance
-
P.C.van Poppel, E.J.van Asseldonk, et al. The interleukin-1 receptor antagonist anakinra improves first-phase insulin secretion and insulinogenic index in subjects with impaired glucose tolerance. Diabetes Obes Metab. 2014;16:1269–1273.
-
(2014)
Diabetes Obes Metab
, vol.16
, pp. 1269-1273
-
-
van Poppel, P.C.1
van Asseldonk, E.J.2
-
73
-
-
77954224428
-
Kinetic approach to pathway attenuation using XOMA 052, a regulatory therapeutic antibody that modulates interleukin-1beta activity
-
M.K.Roell, H.Issafras, R.J.Bauer, et al. Kinetic approach to pathway attenuation using XOMA 052, a regulatory therapeutic antibody that modulates interleukin-1beta activity. J Biol Chem. 2010;285:20607–20614.
-
(2010)
J Biol Chem
, vol.285
, pp. 20607-20614
-
-
Roell, M.K.1
Issafras, H.2
Bauer, R.J.3
-
74
-
-
84864386088
-
Effects of gevokizumab on glycemia and inflammatory markers in type 2 diabetes
-
C.Cavelti-Weder, A.Babians-Brunner, C.Keller, et al. Effects of gevokizumab on glycemia and inflammatory markers in type 2 diabetes. Diabetes Care. 2012;35:1654–1662.
-
(2012)
Diabetes Care
, vol.35
, pp. 1654-1662
-
-
Cavelti-Weder, C.1
Babians-Brunner, A.2
Keller, C.3
-
75
-
-
84873271227
-
Effect of anti-IL-1β antibody (canakinumab) on insulin secretion rates in impaired glucose tolerance or type 2 diabetes: results of a randomized, placebo-controlled trial
-
A.Rissanen, C.P.Howard, J.Botha, et al. Effect of anti-IL-1β antibody (canakinumab) on insulin secretion rates in impaired glucose tolerance or type 2 diabetes: results of a randomized, placebo-controlled trial. Diabetes Obes Metab. 2012;14:1088–1096.
-
(2012)
Diabetes Obes Metab
, vol.14
, pp. 1088-1096
-
-
Rissanen, A.1
Howard, C.P.2
Botha, J.3
-
76
-
-
84870619337
-
Effects of interleukin-1β inhibition with canakinumab on hemoglobin A1c, lipids, C-reactive protein, interleukin-6, and fibrinogen: a phase IIb randomized, placebo-controlled trial
-
P.M.Ridker, C.P.Howard, V.Walter, et al. Effects of interleukin-1β inhibition with canakinumab on hemoglobin A1c, lipids, C-reactive protein, interleukin-6, and fibrinogen: a phase IIb randomized, placebo-controlled trial. Circulation. 2012;126:2739–2748.
-
(2012)
Circulation
, vol.126
, pp. 2739-2748
-
-
Ridker, P.M.1
Howard, C.P.2
Walter, V.3
-
77
-
-
84888440734
-
Prevalence and out-patient medical costs of comorbid conditions in patients with rheumatoid arthritis
-
M.Osiri, Y.Sattayasomboon. Prevalence and out-patient medical costs of comorbid conditions in patients with rheumatoid arthritis. Joint Bone Spine. 2013;80:608–612.
-
(2013)
Joint Bone Spine
, vol.80
, pp. 608-612
-
-
Osiri, M.1
Sattayasomboon, Y.2
-
78
-
-
84941260856
-
Monocytes from patients with rheumatoid arthritis and type 2 diabetes mellitus display an increased production of interleukin (IL)-1β via the nucleotide-binding domain and leucine-rich repeat containing family pyrin 3 (NLRP3)-inflammasome activation: a possible implication for therapeutic decision in these patients
-
P.Ruscitti, P.Cipriani, P.Di Benedetto, et al. Monocytes from patients with rheumatoid arthritis and type 2 diabetes mellitus display an increased production of interleukin (IL)-1β via the nucleotide-binding domain and leucine-rich repeat containing family pyrin 3 (NLRP3)-inflammasome activation: a possible implication for therapeutic decision in these patients. Clin Exp Immunol. 2015;182:35–44.
-
(2015)
Clin Exp Immunol
, vol.182
, pp. 35-44
-
-
Ruscitti, P.1
Cipriani, P.2
Di Benedetto, P.3
-
79
-
-
84934915803
-
Efficacy of inhibition of IL-1 in patients with rheumatoid arthritis and type 2 diabetes mellitus: two case reports and review of the literature
-
P.Ruscitti, P.Cipriani, L.Cantarini, et al. Efficacy of inhibition of IL-1 in patients with rheumatoid arthritis and type 2 diabetes mellitus: two case reports and review of the literature. J Med Case Rep. 2015;9:123.
-
(2015)
J Med Case Rep
, vol.9
, pp. 123
-
-
Ruscitti, P.1
Cipriani, P.2
Cantarini, L.3
-
80
-
-
84963900593
-
FRI0219 Disease severity, no steroid use and type ii diabetes predict response to anakinra (kineret(R)) in patients with rheumatoid arthritis
-
B.Missler-Karger, M.Leu, M.A.Raboisson, et al. FRI0219 Disease severity, no steroid use and type ii diabetes predict response to anakinra (kineret(R)) in patients with rheumatoid arthritis. Ann Rheum Dis. 2013;72:447.
-
(2013)
Ann Rheum Dis
, vol.72
, pp. 447
-
-
Missler-Karger, B.1
Leu, M.2
Raboisson, M.A.3
|