IL-1αβ blockade prevents cartilage and bone destruction in murine type II collagen-induced arthritis, whereas TNF-α blockade only ameliorates joint inflammation

Journal of Immunology

Volumn 163, Issue 9, 1999, Pages 5049-5055

  Joosten, Leo A B ^a,b   Helsen, Monique M A ^b   Saxne, Tore ^c   Van De Loo, Fons A J ^b   Heinegård, Dick ^c   Van Den Berg, Wim B ^b  

^a RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR BINDING PROTEIN;

ANIMAL TISSUE; ARTICLE; BONE DESTRUCTION; CARTILAGE DEGENERATION; DISEASE ACTIVITY; DRUG EFFECT; ENZYME ACTIVITY; HISTOPATHOLOGY; JOINT RADIOGRAPHY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BLOCKING; RHEUMATOID ARTHRITIS;

ANIMALS; ANTIGENS, CD; ARTHRITIS, EXPERIMENTAL; BONE AND BONES; CARTILAGE, ARTICULAR; CATTLE; COLLAGEN; EPITOPES; EXTRACELLULAR MATRIX PROTEINS; GLYCOPROTEINS; IMMUNE SERA; INJECTIONS, INTRAPERITONEAL; INTERLEUKIN-1; JOINTS; MALE; MICE; MICE, INBRED DBA; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; RECEPTORS, TUMOR NECROSIS FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; TARSUS, ANIMAL; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0032752705     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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