Toll like receptor 9 antagonism modulates spinal cord neuronal function and survival: Direct versus astrocyte-mediated mechanisms

Brain, Behavior, and Immunity

Volumn 56, Issue , 2016, Pages 310-324

  Acioglu, Cigdem ^a,b   Mirabelli, Ersilia ^a,c   Baykal, Ahmet Tarik ^d   Ni, Li ^a   Ratnayake, Ayomi ^a   Heary, Robert F ^a   Elkabes, Stella ^a  

^a RUTGERS UNIVERSITY   (United States)

^b KILIS 7 ARALIK UNIVERSITY   (Turkey)

^c RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^d ACIBADEM UNIVERSITY   (Turkey)

Author keywords

Chemokine; CpG ODN; Cytokine; DAMP; Endoplasmic reticulum stress; Excitotoxicity; Injury; Innate immunity; Neurodegeneration; Neuroprotection; Pattern recognition receptors

Indexed keywords

CHEMOKINE; CPG OLIGODEOXYNUCLEOTIDE; CXCL1 CHEMOKINE; INTERLEUKIN 6; KAINIC ACID; MONOCYTE CHEMOTACTIC PROTEIN 1; TOLL LIKE RECEPTOR 9; TOLL LIKE RECEPTOR AFFECTING AGENT; GUANOSINE; NEUROPROTECTIVE AGENT; OLIGODEOXYRIBONUCLEOTIDE; PYRIMIDINE NUCLEOTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL FUNCTION; CELL INTERACTION; CELL SURVIVAL; CELL VIABILITY; COCULTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; EMBRYO; ENDOPLASMIC RETICULUM STRESS; EXCITOTOXICITY; FEMALE; IN VITRO STUDY; MACROGLIA; MOUSE; NERVE CELL DEGENERATION; NERVE CELL GROWTH; NERVE CELL NECROSIS; NERVOUS SYSTEM INFLAMMATION; NEUROMODULATION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RECEPTOR BLOCKING; SPINAL CORD NERVE CELL; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL CULTURE; DRUG EFFECTS; KNOCKOUT MOUSE; NERVE CELL; PREGNANCY; SPINAL CORD;

ANIMALS; ASTROCYTES; CELLS, CULTURED; CYTOSINE NUCLEOTIDES; ENDOPLASMIC RETICULUM STRESS; FEMALE; GUANOSINE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURONS; NEUROPROTECTIVE AGENTS; OLIGODEOXYRIBONUCLEOTIDES; PREGNANCY; SPINAL CORD; TOLL-LIKE RECEPTOR 9;

EID: 84963571382     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2016.03.027     Document Type: Article

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